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1. Global surveillance of trends in cancer survival 2000-14 (concord-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries

Author

Claudia Allemani, Tomohiro Matsuda, Veronica Di Carlo, Rhea Harewood, Melissa Matz, Maja Nikšić, Audrey Bonaventure, Mikhail Valkov, Christopher J Johnson, Jacques Estève, Olufemi J Ogunbiyi, Gulnar Azevedo e Silva, Wan-Qing Chen, Sultan Eser, Gerda Engholm, Charles A Stiller, Alain Monnereau, Ryan R Woods, Otto Visser, Gek Hsiang Lim, Joanne Aitken, Hannah K Weir, Michel P Coleman, S Bouzbid, M Hamdi-Chérif, Z Zaidi, K Meguenni, D Regagba, S Bayo, T Cheick Bougadari, S S Manraj, A Fabowale, O J Ogunbiyi, D Bradshaw, N I M Somdyala, I Kumcher, F Moreno, G H Calabrano, S B Espinola, B Carballo Quintero, R Fita, M C Diumenjo, W D Laspada, S G Ibañez, C A Lima, P C F De Souza, K Del Pino, C Laporte, M P Curado, J C de Oliveira, C L A Veneziano, D B Veneziano, M R D O Latorre, L F Tanaka, M S Rebelo, M O Santos, G Azevedo e Silva, J C Galaz, M Aparicio Aravena, J Sanhueza Monsalve, D A Herrmann, S Vargas, V M Herrera, C J Uribe, L E Bravo, L S Garcia, N E Arias-Ortiz, D Morantes, D M Jurado, M C Yépez Chamorro, S Delgado, M Ramirez, Y H Galán Alvarez, P Torres, F Martínez-Reyes, L Jaramillo, R Quinto, J, M Mendoza, P Cueva, J G Yépez, B Bhakkan, J Deloumeaux, C Joachim, J Macni, R Carrillo, J Shalkow Klincovstein, R Rivera Gomez, E Poquioma, G Tortolero-Luna, D Zavala, R Alonso, E Barrios, A Eckstrand, C Nikiforuk, R R Woods, G Noonan, D Turner, E Kumar, B Zhang, F R McCrate, S Ryan, M MacIntyre, N Saint-Jacques, D E Nishri, C A McClure, K A Vriends, S Kozie, H Stuart-Panko, T Freeman, J T George, J T Brockhouse, D K O'Brien, A Holt, L Almon, S Kwong, C Morris, R Rycroft, L Mueller, C E Phillips, H Brown, B Cromartie, A G Schwartz, F Vigneau, G M Levin, B Wohler, R Bayakly, K C Ward, S L Gomez, M McKinley, R Cress, M D Green, K Miyagi, C J Johnson, L P Ruppert, C F Lynch, B Huang, T C Tucker, D Deapen, L Liu, M C Hsieh, X C Wu, M Schwenn, S T Gershman, R C Knowlton, G Alverson, G E Copeland, S Bushhouse, D B Rogers, J Jackson-Thompson, D Lemons, H J Zimmerman, M Hood, J Roberts-Johnson, J R Rees, B Riddle, K S Pawlish, A Stroup, C Key, C Wiggins, A R Kahn, M J Schymura, S Radhakrishnan, C Rao, L K Giljahn, R M Slocumb, R E Espinoza, F Khan, K G Aird, T Beran, J J Rubertone, S J Slack, L Garcia, D L Rousseau, T A Janes, S M Schwartz, S W Bolick, D M Hurley, M A Whiteside, P Miller-Gianturco, M A Williams, K Herget, C Sweeney, A T Johnson, M B Keitheri Cheteri, P Migliore Santiago, S E Blankenship, S Farley, R Borchers, R Malicki, J R Espinoza, J Grandpre, H K Weir, R Wilson, B K Edwards, A Mariotto. Y Lei, N Wang, J S Chen, Y Zhou, Y T He, G H Song, X P Gu, D Mei, H J Mu, H M Ge, T H Wu, Y Y Li, D L Zhao, F Jin, J H Zhang, F D Zhu, Q Junhua, Y L Yang, C X Jiang, W Biao, J Wang, Q L Li, H Yi, X Zhou, J Dong, W Li, F X Fu, S Z Liu, J G Chen, J Zhu, Y H Li, Y Q Lu, M Fan, S Q Huang, G P Guo, H Zhaolai, K Wei, W Q Chen, H Zeng, A V Demetriou, W K Mang, K C Ngan, A C Kataki, M Krishnatreya, P A Jayalekshmi, P Sebastian, A Nandakumar, R Malekzadeh, G Roshandel, L Keinan-Boker, B G Silverman, H Ito, H Nakagawa, M Sato, F Tobori, I Nakata, N Teramoto, M Hattori, Y Kaizaki, F Moki, H Sugiyama, M Utada, M Nishimura, K Yoshida, K Kurosawa, Y Nemoto, H Narimatsu, M Sakaguchi, S Kanemura, M Naito, R Narisawa, I Miyashiro, K Nakata, S Sato, M Yoshii, I Oki, N Fukushima, A Shibata, K Iwasa, C Ono, T Matsuda, O Nimri, K W Jung, Y J Won, E Alawadhi, A Elbasmi, A Ab Manan, F Adam, E Sanjaajmats, U Tudev, C Ochir, A M Al Khater, M M El Mistiri, G H Lim, Y Y Teo, C J Chiang, W C Lee, R Buasom, S Sangrajrang, S Kamsaard, S Wiangnon, K Daoprasert, D Pongnikorn, A Leklob, S Sangkitipaiboon, S L Geater, H Sriplung, O Ceylan, I Kög, O Dirican, T Köse, T Gurbuz, F E Karaşahin, D Turhan, U Aktaş, Y Halat, S Eser, C I Yakut, M Altinisik, Y Cavusoglu, A Türkköylü, N Üçüncü, M Hackl, A A Zborovskaya, O V Aleinikova, K Henau, L Van Eycken, Z Valerianova, M R Yordanova, M Šekerija, L Dušek, M Zvolský, G Engholm, H Storm, K Innos, M Mägi, N Malila, K Seppä, J Jégu, M Velten, E Cornet, X Troussard, A M Bouvier, A V Guizard, V Bouvier, G Launoy, P Arveux, M Maynadié, M Mounier, A S Worono, M Daoulas, M Robaszkiewicz, J Clavel, S Goujon, B Lacour, I Baldi, C Pouchieu, B Amadeo, G Coureau, A Monnereau, S Orazio, P M Preux, F Rharbaoui, E Marrer, B Trétarre, M Colonna, P Delafosse, K Ligier, S Plouvier, A Cowppli-Bony, F Molinié, S Bara, O Ganry, B Lapôtre- Ledoux, P Grosclaude, N Bossard, Z Uhry, F Bray, M Piñeros, J Estève, R Stabenow, H Wilsdorf-Köhler, A Eberle, S Luttmann, I Löhden, A L Nennecke, J Kieschke, E Sirri, K Emrich, S R Zeissig, B Holleczek, N Eisemann, A Katalinic, R A Asquez, V Kumar, E Petridou, E J Ólafsdóttir, L Tryggvadóttir, K Clough-Gorr, P M Walsh, H Sundseth, G Mazzoleni, F Vittadello, E Coviello, F Cuccaro, R Galasso, G Sampietro, A Giacomin, M Magoni, A Ardizzone, A D'Argenzio, M Castaing, G Grosso, A M Lavecchia, A Sutera Sardo, G Gola, L Gatti, P Ricci, S Ferretti, D Serraino, A Zucchetto, M V Celesia, R A Filiberti, F Pannozzo, A Melcarne, F Quarta, A G Russo, G Carrozzi, C Cirilli, L Cavalieri d'Oro, M Rognoni, M Fusco, M F Vitale, M Usala, R Cusimano, W Mazzucco, M Michiara, P Sgargi, L Boschetti, E Borciani, P Seghini, M M Maule, F Merletti, R Tumino, P Mancuso, M Vicentini, T Cassetti, R Sassatelli, F Falcini, S Giorgetti, A L Caiazzo, R Cavallo, R Cesaraccio, D R Pirino, M L Contrino, F Tisano, A C Fanetti, S Maspero, S Carone, A Mincuzzi, G Candela, T Scuderi, M A Gentilini, S Pier, S Rosso, A Barchielli, A Caldarella, F Bianconi, F Stracci, P Contiero, G Tagliabue, M Rugge, M Zorzi, S Beggiato, A Brustolin, F Berrino, G Gatta, M Sant, C Buzzoni, L Mangone, R Capocaccia, R De Angelis, R Zanetti, A Maurina, S Pildava, N Lipunova, I Vincerževskienė, D Agius, N Calleja, S Siesling, O Visser, Larønningen, B Møller, A Dyzmann-Sroka, M Trojanowski, S Góźdź, R Mężyk, T Mierzwa, L Molong, J Rachtan, S Szewczyk, J Błaszczyk, K Kępska, B Kościańska, K Tarocińska, M Zwierko, K Drosik, K M Maksimowicz, E Purwin-Porowska, E Reca, J Wójcik-Tomaszewska, A Tukiendorf, M Grądalska-Lampart, A U Radziszewska, A Gos, M Talerczyk, M Wyborska, J A Didkowska, U Wojciechowska, M Bielska-Lasota, G Forjaz de Lacerda, R A Rego, J Bastos, M A Silva, L Antunes, J Laranja Pontes, A Mayer-da-Silva, A Miranda, L M Blaga, D Coza, Russia: M Y Valkov, L Gusenkova, O Lazarevich, O Prudnikova, D M Vjushkov, A G Egorova, A E Orlov, L A Kudyakov, L V Pikalova, J Adamcik, C Safaei Diba, M Primic-Žakelj, V Zadnik, N Larrañaga, A Lopez de Munain, A A Herrera, R Redondas, R Marcos-Gragera, M L Vilardell Gil, E Molina, M J Sánchez Perez, P Franch Sureda, M Ramos Montserrat, M D Chirlaque, C Navarro, E E Ardanaz, M M Guevara, R Fernández-Delgado, R Peris-Bonet, M Carulla, J Galceran, C Alberich, M Vicente-Raneda, S Khan, D Pettersson, P Dickman, I Avelina, K Staehelin, B Camey, C Bouchardy, R Schaar, H Frick, C Herrmann, J L Bulliard, M Maspoli-Conconi, C E Kuehni, S M Redmond, A Bordoni, L Ortelli, A Chiolero, I Konzelmann, K L Matthes, S Rohrmann, Broggio, J Rashbass, D Fitzpatrick, A Gavin, D I Clark, A J Deas, D W Huws, C White, C Allemani, A Bonaventure, M P Coleman, V Di Carlo, R Harewood, M Matz, L Montel, M Nikšić, B Rachet, A D Turculeț, R Stephens, C A Stiller, E Chalker, H Phung, R Walton, H You, S Guthridge, F Johnson, J Aitken, P Gordon, K D'Onise, K Priest, B C Stokes, A Venn, H Farrugia, V Thurs eld, J Dowlin, D Currow, J Hendrix, C Lewis, Tıp Fakültesi, Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), and Claudia Allemani, Tomohiro Matsuda, Veronica Di Carlo, Rhea Harewood, Melissa Matz, Maja Nikšić, Audrey Bonaventure, Mikhail Valkov, Christopher J Johnson, Jacques Estève, Olufemi J Ogunbiyi, Gulnar Azevedo e Silva, Wan-Qing Chen, Sultan Eser, Gerda Engholm, Charles A Stiller, Alain Monnereau, Ryan R Woods, Otto Visser, Gek Hsiang Lim, Joanne Aitken, Hannah K Weir, Michel P Coleman, S Bouzbid, M Hamdi-Chérif, Z Zaidi, K Meguenni, D Regagba, S Bayo, T Cheick Bougadari, S S Manraj, A Fabowale, O J Ogunbiyi, D Bradshaw, N I M Somdyala, I Kumcher, F Moreno, G H Calabrano, S B Espinola, B Carballo Quintero, R Fita, M C Diumenjo, W D Laspada, S G Ibañez, C A Lima, P C F De Souza, K Del Pino, C Laporte, M P Curado, J C de Oliveira, C L A Veneziano, D B Veneziano, M R D O Latorre, L F Tanaka, M S Rebelo, M O Santos, G Azevedo e Silva, J C Galaz, M Aparicio Aravena, J Sanhueza Monsalve, D A Herrmann, S Vargas, V M Herrera, C J Uribe, L E Bravo, L S Garcia, N E Arias-Ortiz, D Morantes, D M Jurado, M C Yépez Chamorro, S Delgado, M Ramirez, Y H Galán Alvarez, P Torres, F Martínez-Reyes, L Jaramillo, R Quinto, J, M Mendoza, P Cueva, J G Yépez, B Bhakkan, J Deloumeaux, C Joachim, J Macni, R Carrillo, J Shalkow Klincovstein, R Rivera Gomez, E Poquioma, G Tortolero-Luna, D Zavala, R Alonso, E Barrios, A Eckstrand, C Nikiforuk, R R Woods, G Noonan, D Turner, E Kumar, B Zhang, F R McCrate, S Ryan, M MacIntyre, N Saint-Jacques, D E Nishri, C A McClure, K A Vriends, S Kozie, H Stuart-Panko, T Freeman, J T George, J T Brockhouse, D K O'Brien, A Holt, L Almon, S Kwong, C Morris, R Rycroft, L Mueller, C E Phillips, H Brown, B Cromartie, A G Schwartz, F Vigneau, G M Levin, B Wohler, R Bayakly, K C Ward, S L Gomez, M McKinley, R Cress, M D Green, K Miyagi, C J Johnson, L P Ruppert, C F Lynch, B Huang, T C Tucker, D Deapen, L Liu, M C Hsieh, X C Wu, M Schwenn, S T Gershman, R C Knowlton, G Alverson, G E Copeland, S Bushhouse, D B Rogers, J Jackson-Thompson, D Lemons, H J Zimmerman, M Hood, J Roberts-Johnson, J R Rees, B Riddle, K S Pawlish, A Stroup, C Key, C Wiggins, A R Kahn, M J Schymura, S Radhakrishnan, C Rao, L K Giljahn, R M Slocumb, R E Espinoza, F Khan, K G Aird, T Beran, J J Rubertone, S J Slack, L Garcia, D L Rousseau, T A Janes, S M Schwartz, S W Bolick, D M Hurley, M A Whiteside, P Miller-Gianturco, M A Williams, K Herget, C Sweeney, A T Johnson, M B Keitheri Cheteri, P Migliore Santiago, S E Blankenship, S Farley, R Borchers, R Malicki, J R Espinoza, J Grandpre, H K Weir, R Wilson, B K Edwards, A Mariotto. Y Lei, N Wang, J S Chen, Y Zhou, Y T He, G H Song, X P Gu, D Mei, H J Mu, H M Ge, T H Wu, Y Y Li, D L Zhao, F Jin, J H Zhang, F D Zhu, Q Junhua, Y L Yang, C X Jiang, W Biao, J Wang, Q L Li, H Yi, X Zhou, J Dong, W Li, F X Fu, S Z Liu, J G Chen, J Zhu, Y H Li, Y Q Lu, M Fan, S Q Huang, G P Guo, H Zhaolai, K Wei, W Q Chen, H Zeng, A V Demetriou, W K Mang, K C Ngan, A C Kataki, M Krishnatreya, P A Jayalekshmi, P Sebastian, A Nandakumar, R Malekzadeh, G Roshandel, L Keinan-Boker, B G Silverman, H Ito, H Nakagawa, M Sato, F Tobori, I Nakata, N Teramoto, M Hattori, Y Kaizaki, F Moki, H Sugiyama, M Utada, M Nishimura, K Yoshida, K Kurosawa, Y Nemoto, H Narimatsu, M Sakaguchi, S Kanemura, M Naito, R Narisawa, I Miyashiro, K Nakata, S Sato, M Yoshii, I Oki, N Fukushima, A Shibata, K Iwasa, C Ono, T Matsuda, O Nimri, K W Jung, Y J Won, E Alawadhi, A Elbasmi, A Ab Manan, F Adam, E Sanjaajmats, U Tudev, C Ochir, A M Al Khater, M M El Mistiri, G H Lim, Y Y Teo, C J Chiang, W C Lee, R Buasom, S Sangrajrang, S Kamsaard, S Wiangnon, K Daoprasert, D Pongnikorn, A Leklob, S Sangkitipaiboon, S L Geater, H Sriplung, O Ceylan, I Kög, O Dirican, T Köse, T Gurbuz, F E Karaşahin, D Turhan, U Aktaş, Y Halat, S Eser, C I Yakut, M Altinisik, Y Cavusoglu, A Türkköylü, N Üçüncü, M Hackl, A A Zborovskaya, O V Aleinikova, K Henau, L Van Eycken, Z Valerianova, M R Yordanova, M Šekerija, L Dušek, M Zvolský, G Engholm, H Storm, K Innos, M Mägi, N Malila, K Seppä, J Jégu, M Velten, E Cornet, X Troussard, A M Bouvier, A V Guizard, V Bouvier, G Launoy, P Arveux, M Maynadié, M Mounier, A S Worono, M Daoulas, M Robaszkiewicz, J Clavel, S Goujon, B Lacour, I Baldi, C Pouchieu, B Amadeo, G Coureau, A Monnereau, S Orazio, P M Preux, F Rharbaoui, E Marrer, B Trétarre, M Colonna, P Delafosse, K Ligier, S Plouvier, A Cowppli-Bony, F Molinié, S Bara, O Ganry, B Lapôtre- Ledoux, P Grosclaude, N Bossard, Z Uhry, F Bray, M Piñeros, J Estève, R Stabenow, H Wilsdorf-Köhler, A Eberle, S Luttmann, I Löhden, A L Nennecke, J Kieschke, E Sirri, K Emrich, S R Zeissig, B Holleczek, N Eisemann, A Katalinic, R A Asquez, V Kumar, E Petridou, E J Ólafsdóttir, L Tryggvadóttir, K Clough-Gorr, P M Walsh, H Sundseth, G Mazzoleni, F Vittadello, E Coviello, F Cuccaro, R Galasso, G Sampietro, A Giacomin, M Magoni, A Ardizzone, A D'Argenzio, M Castaing, G Grosso, A M Lavecchia, A Sutera Sardo, G Gola, L Gatti, P Ricci, S Ferretti, D Serraino, A Zucchetto, M V Celesia, R A Filiberti, F Pannozzo, A Melcarne, F Quarta, A G Russo, G Carrozzi, C Cirilli, L Cavalieri d'Oro, M Rognoni, M Fusco, M F Vitale, M Usala, R Cusimano, W Mazzucco, M Michiara, P Sgargi, L Boschetti, E Borciani, P Seghini, M M Maule, F Merletti, R Tumino, P Mancuso, M Vicentini, T Cassetti, R Sassatelli, F Falcini, S Giorgetti, A L Caiazzo, R Cavallo, R Cesaraccio, D R Pirino, M L Contrino, F Tisano, A C Fanetti, S Maspero, S Carone, A Mincuzzi, G Candela, T Scuderi, M A Gentilini, S Pier, S Rosso, A Barchielli, A Caldarella, F Bianconi, F Stracci, P Contiero, G Tagliabue, M Rugge, M Zorzi, S Beggiato, A Brustolin, F Berrino, G Gatta, M Sant, C Buzzoni, L Mangone, R Capocaccia, R De Angelis, R Zanetti, A Maurina, S Pildava, N Lipunova, I Vincerževskienė, D Agius, N Calleja, S Siesling, O Visser, Larønningen, B Møller, A Dyzmann-Sroka, M Trojanowski, S Góźdź, R Mężyk, T Mierzwa, L Molong, J Rachtan, S Szewczyk, J Błaszczyk, K Kępska, B Kościańska, K Tarocińska, M Zwierko, K Drosik, K M Maksimowicz, E Purwin-Porowska, E Reca, J Wójcik-Tomaszewska, A Tukiendorf, M Grądalska-Lampart, A U Radziszewska, A Gos, M Talerczyk, M Wyborska, J A Didkowska, U Wojciechowska, M Bielska-Lasota, G Forjaz de Lacerda, R A Rego, J Bastos, M A Silva, L Antunes, J Laranja Pontes, A Mayer-da-Silva, A Miranda, L M Blaga, D Coza, Russia: M Y Valkov, L Gusenkova, O Lazarevich, O Prudnikova, D M Vjushkov, A G Egorova, A E Orlov, L A Kudyakov, L V Pikalova, J Adamcik, C Safaei Diba, M Primic-Žakelj, V Zadnik, N Larrañaga, A Lopez de Munain, A A Herrera, R Redondas, R Marcos-Gragera, M L Vilardell Gil, E Molina, M J Sánchez Perez, P Franch Sureda, M Ramos Montserrat, M D Chirlaque, C Navarro, E E Ardanaz, M M Guevara, R Fernández-Delgado, R Peris-Bonet, M Carulla, J Galceran, C Alberich, M Vicente-Raneda, S Khan, D Pettersson, P Dickman, I Avelina, K Staehelin, B Camey, C Bouchardy, R Schaar, H Frick, C Herrmann, J L Bulliard, M Maspoli-Conconi, C E Kuehni, S M Redmond, A Bordoni, L Ortelli, A Chiolero, I Konzelmann, K L Matthes, S Rohrmann, Broggio, J Rashbass, D Fitzpatrick, A Gavin, D I Clark, A J Deas, D W Huws, C White, C Allemani, A Bonaventure, M P Coleman, V Di Carlo, R Harewood, M Matz, L Montel, M Nikšić, B Rachet, A D Turculeț, R Stephens, C A Stiller, E Chalker, H Phung, R Walton, H You, S Guthridge, F Johnson, J Aitken, P Gordon, K D'Onise, K Priest, B C Stokes, A Venn, H Farrugia, V Thurs eld, J Dowlin, D Currow, J Hendrix, C Lewis

Subjects
0301 basic medicine, Universal Health Coverage, population-based registries, Relative Survival, Settore MED/42 - Igiene Generale E Applicata, Cancer -- Treatment, Humans, Neoplasms, Population Surveillance, Registries, Survival Rate, Medicine (all), 0302 clinical medicine, cancer survival, education.field_of_study, Relative survival, EPICENE, General Medicine, 3. Good health, trend, 030220 oncology & carcinogenesis, Public-Health, cancer surveillance, Liver cancer, survival, cancer registry, CONCORD-3, Cure, Childhood-Cancer, medicine.medical_specialty, population-based cancer registries, Womens Cancers, Population, Medicine (all),cancer survival, population-based cancer registries, Socio-culturale, United-States, Article, 03 medical and health sciences, Breast cancer, Cancer epidemiology, medicine, Nordic-Countries, Cancer -- Mortality, education, Survival rate, Cancer prevention, Alternative Approach, business.industry, Public health, Cancer, Cancer -- Patients -- Long-term care, medicine.disease, 030104 developmental biology, High-Income Countries, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, business, Demography
Abstract

Eser, Sultan (Balikesir Author), Background In 2015, the second cycle of the CONCORD programme established global surveillance of cancer survival as a metric of the effectiveness of health systems and to inform global policy on cancer control. CONCORD-3 updates the worldwide surveillance of cancer survival to 2014. Methods CONCORD-3 includes individual records for 37.5 million patients diagnosed with cancer during the 15-year period 2000-14. Data were provided by 322 population-based cancer registries in 71 countries and territories, 47 of which provided data with 100% population coverage. The study includes 18 cancers or groups of cancers: oesophagus, stomach, colon, rectum, liver, pancreas, lung, breast (women), cervix, ovary, prostate, and melanoma of the skin in adults, and brain tumours, leukaemias, and lymphomas in both adults and children. Standardised quality control procedures were applied; errors were rectified by the registry concerned. We estimated 5-year net survival. Estimates were age-standardised with the International Cancer Survival Standard weights.Findings For most cancers, 5-year net survival remains among the highest in the world in the USA and Canada, in Australia and New Zealand, and in Finland, Iceland, Norway, and Sweden. For many cancers, Denmark is closing the survival gap with the other Nordic countries. Survival trends are generally increasing, even for some of the more lethal cancers: in some countries, survival has increased by up to 5% for cancers of the liver, pancreas, and lung. For women diagnosed during 2010-14, 5-year survival for breast cancer is now 89.5% in Australia and 90.2% in the USA, but international differences remain very wide, with levels as low as 66.1% in India. For gastrointestinal cancers, the highest levels of 5-year survival are seen in southeast Asia: in South Korea for cancers of the stomach (68.9%), colon (71.8%), and rectum (71.1%); in Japan for oesophageal cancer (36.0%); and in Taiwan for liver cancer (27.9%). By contrast, in the same world region, survival is generally lower than elsewhere for melanoma of the skin (59.9% in South Korea, 52.1% in Taiwan, and 49.6% in China), and for both lymphoid malignancies (52.5%, 50.5%, and 38.3%) and myeloid malignancies (45.9%, 33.4%, and 24.8%). For children diagnosed during 2010-14, 5-year survival for acute lymphoblastic leukaemia ranged from 49.8% in Ecuador to 95.2% in Finland. 5-year survival from brain tumours in children is higher than for adults but the global range is very wide (from 28.9% in Brazil to nearly 80% in Sweden and Denmark). Interpretation The CONCORD programme enables timely comparisons of the overall effectiveness of health systems in providing care for 18 cancers that collectively represent 75% of all cancers diagnosed worldwide every year. It contributes to the evidence base for global policy on cancer control. Since 2017, the Organisation for Economic Co-operation and Development has used findings from the CONCORD programme as the official benchmark of cancer survival, among their indicators of the quality of health care in 48 countries worldwide. Governments must recognise population-based cancer registries as key policy tools that can be used to evaluate both the impact of cancer prevention strategies and the effectiveness of health systems for all patients diagnosed with cancer., American Cancer Society Centers for Disease Control and Prevention Swiss Re Swiss Cancer Research foundation Swiss Cancer League Institut National du Cancer La Ligue Contre le Cancer Rossy Family Foundation US National Cancer Institute Susan G Komen Foundation

Published
2018

4. Beta-adrenoceptor blockers in atrial fibrillation: the importance of partial agonist activity [see comments]

Author

J. R. Rees, Michael A. James, K.S. Channer, and T MacConnell

Subjects
Pharmacology, Tachycardia, Bradycardia, Digoxin, Heart disease, business.industry, Atrial fibrillation, Atenolol, medicine.disease, Anesthesia, Heart rate, medicine, Pharmacology (medical), cardiovascular diseases, medicine.symptom, Pindolol, business, medicine.drug
Abstract

1. The ideal drug treatment for atrial fibrillation will control resting heart rate, blunt exercise induced tachycardia whilst not exacerbating nocturnal bradycardia. Monotherapy with digoxin may not be ideal. We have compared the effect of combining digoxin (0.25 mg daily) with atenolol 50 mg and 100 mg or pindolol 5 mg twice daily and 15 mg twice daily in a cross-over randomised single-blind trial in eight symptomatic patients (six male; mean age 62 years) with poorly controlled atrial fibrillation. 2. Heart rate control was measured by 24 h ECG at baseline on digoxin therapy and after 2 weeks with each treatment. Symptom scores for breathlessness and palpitation were measured using visual analogue scales. 3. The addition of both beta-adrenoceptor blockers significantly reduced mean diurnal maximum heart rate from baseline (all P 1.5 s (P = 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

Published
1994

8. The epidemiological features of invasive mycotic infections in the San Francisco Bay area, 1992-1993: results of population-based laboratory active surveillance

Author

J R, Rees, R W, Pinner, R A, Hajjeh, M E, Brandt, and A L, Reingold

Subjects
Age Distribution, Mycoses, Data Collection, Incidence, Population Surveillance, Fungi, Humans, San Francisco, Opportunistic Infections, California
Abstract

Population-based active laboratory surveillance for invasive mycotic infections was conducted during 1992 and 1993 in three California counties: Alameda, Contra Costa, and San Francisco (population, 2.94 million). The cumulative incidence of invasive mycotic infections was 178.3 per million per year. Invasive mycoses were most commonly caused by Candida (72.8 per million per year), Cryptococcus (65.5), Coccidioides (15.3), Aspergillus (12.4), and Histoplasma (7.1). The clinical significance of other, less common fungi was determined by detailed chart review. The cumulative incidence was determined for zygomycosis (1.7 per million per year), hyalohyphomycosis (1.2), and phaeohyphomycosis (1.0). The most common underlying conditions were human immunodeficiency virus infection (47.4%), nonhematologic malignancy (14.7%), diabetes mellitus (9.9%), and chronic lung disease (9.3%). This represents the first population-based epidemiological assessment of invasive mycoses in the United States.

Published
1998

9. PTU-140 Neutrophil lymphocyte ratio in outcome prediction after emergency abdominal surgery in the elderly

Author

P G Vaughan-Shaw, J R Rees, and A T King

Subjects
Univariate analysis, Multivariate statistics, medicine.medical_specialty, Multivariate analysis, biology, business.industry, Lymphocyte, C-reactive protein, Gastroenterology, Univariate, Surgery, medicine.anatomical_structure, Internal medicine, medicine, biology.protein, Time point, business, Abdominal surgery
Abstract

Introduction Accurate prediction of outcome after emergency surgery in the elderly patient may assist decision making. However, certain scoring systems require post-operative data (eg, P-POSSUM) while others have failed to gain widespread use (eg, Surgical risk score). Recent reports have suggested that C reactive protein (CRP) and the neutrophil lymphocyte (N/L ratio) ratio may predict surgical outcome. Methods A retrospective review of consecutive unselected patients aged 80 years or over undergoing emergency abdominal surgery over a 22-month period was performed. Univariate, multivariate and recursive analyses were performed and findings validated using an independent data-set. Results 88 patients were identified, median age 84 years. 30-day mortality was 31%, 6-month mortality 43% and 12-month mortality 50%. Univariate analysis revealed age, N/L ratio, CRP, midline laparotomy, ASA and surgical risk score to predict outcome at set time points. Using a recursive approach N/L ratio>22 (p=0.0018) best predicted 30-day outcome. On multivariate analysis, N/L ratio was an independent predictor of 30-day outcome (p=0.004, df=1, χ 2 =8.144) while CRP failed to predict outcome at any time point. In an independent dataset (n=84), N/L ratio was an independent prognostic factor at 30 days (p=0.001, df=2, χ 2 =15.071), 6 months (p 2 =12.536) and 12 months (p=0.001, df=1 χ 2 =10.27). Conclusion We suggest that N/L is an easily calculable pre-operative measure that may have utility in the prediction of outcome after emergency abdominal surgery in the elderly. Further work to validate this measure in a larger, prospective setting and determine why N/L ratio predicts outcome is necessary. Competing interests None declared.

Published
2012

10. Transient cortical blindness after coronary angiography

Author

Peter Wilde, J R Rees, and R Parry

Subjects
Male, Coronary angiography, medicine.medical_specialty, medicine.diagnostic_test, Cortical blindness, business.industry, Brain, Infarction, Computed tomography, Middle Aged, Blindness, Coronary Angiography, medicine.disease, Iopamidol, Contrast medium, Transient visual loss, medicine, Humans, Radiology, Tomography, X-Ray Computed, Cardiology and Cardiovascular Medicine, business, Extravasation of Diagnostic and Therapeutic Materials, Research Article
Abstract

Transient visual loss lasting three days developed after transfemoral coronary angiography in a 62 year old man. Computed tomography (CT) showed bilateral leakage of contrast medium into the occipital cortex. A repeat CT scan after his sight recovered showed clearance of contrast with no underlying infarction. A breakdown of the blood-brain barrier with direct neurotoxicity of the contrast media seemed to be the cause of these neurological changes after coronary angiography which apparently have not been reported before.

Published
1993

12. Management of Transmural Peptic Strictures of the Esophagus

Author

J R Rees, B Thorbjarnarson, and W A Barnes

Subjects
Adult, Male, medicine.medical_specialty, Peptic, Postoperative Complications, Methods, Humans, Medicine, Anemia, Macrocytic, Esophagus, Aged, Retrospective Studies, Hernia, Diaphragmatic, business.industry, General surgery, Body Weight, Middle Aged, Jejunum, medicine.anatomical_structure, Evaluation Studies as Topic, Esophageal Stenosis, Gastroesophageal Reflux, Female, Surgery, Esophagogastric Junction, Gastrointestinal Hemorrhage, business, Research Article
Published
1974

13. Myocardial ultrastructure and the development of atrioventricular block in Kearns-Sayre syndrome

Author

J R Rees, R. G. Charles, J M Kay, E J Epstein, and S Holt

Subjects
Adult, Male, Pathology, medicine.medical_specialty, Mitochondria, Heart, Kearns–Sayre syndrome, Myofibrils, Myocardial ultrastructure, Physiology (medical), Humans, Medicine, Pigment Epithelium of Eye, Ophthalmoplegia, Sarcolemma, business.industry, Myocardium, External ophthalmoplegia, Syndrome, medicine.disease, Heart Block, cardiovascular system, Retinal pigmentation, Ultrastructure, Female, Cardiology and Cardiovascular Medicine, business, Myofibril, Pigmentation Disorders, Atrioventricular block
Abstract

A right ventricular endomyocardial biopsy specimen from a 30-year-old male with chromic progressive external ophthalmoplegia, retinal pigmentation and complete atrioventricular block (Kearns-Sayre syndrome) was examined in the electron microscope. There was a proliferation of mitochondria between the myofibrils and beneath the sarcolemma. Many of the mitochondria showed morphologic abnormalities not previously described in this condition. There were associated accumulations of glycogen. A similarly affected female with left anterior hemiblock developed complete atrioventricular block at age 26 years, Despite the ultrastructural changes, clinically detectable myocardial disease is not a feature of Kearns-Sayre syndrome. However, intraventricular conduction defects show an unusually rapid progression to potentially fatal complete atrioventricular block and are an indication for prophylactic cardiac pacing.

Published
1981

14. The Positron-Electron Project-PEP

Author

J. R. Rees

Subjects
Physics, Nuclear and High Energy Physics, medicine.medical_specialty, Nuclear Energy and Engineering, Systems engineering, medicine, Physics::Accelerator Physics, High Energy Physics::Experiment, Medical physics, Electrical and Electronic Engineering, Rf system
Abstract

PEP, an 18-GeV electron-positron colliding-beam storage ring facility at SLAC, is being built by a team from LBL and SLAC. Construction is under way and completion is scheduled for Fall of 1979. This report summarizes the design of the facility and reports on the status of the project.

Published
1977

15. Spear II Performance

Author

M. J. Lee, N. Dean, J. M. Paterson, R. Melen, R. A. McConnell, T. Taylor, J.-L. Pellegrin, M. A. Allen, R. Helm, W. Davies-White, L. G. Karvonen, G. E. Fischer, E. Keil, P. Morton, J. Harris, H. Wiedemann, J. R. Rees, Perry B. Wilson, Alex Chao, Burton Richter, B. E. Humphrey, R. Bennett, and A. P. Sabersky

Subjects
Physics, Nuclear and High Energy Physics, Resonance, Synchrotron radiation, Instability, Linear particle accelerator, Nuclear physics, Nuclear Energy and Engineering, Physics::Accelerator Physics, Harmonic number, Electrical and Electronic Engineering, Spear, Atomic physics, Beam (structure), Storage ring
Abstract

The single beam and colliding beam performance of the SLAC electron-positron storage ring SPEAR II is described. The sevenfold increase in harmonic number in SPEAR II in comparison to SPEAR I has made significant changes in single beam behavior. Strong synchrobetatron resonances and a new transverse instability are observed and our first studies of these phenomena are described, Measurements on current dependent bunch lengthening are presented.

Published
1975

16. The Pep Storage Ring - Current Status

Author

J. R. Rees

Subjects
Physics, Magnetic circuit, Nuclear and High Energy Physics, Nuclear Energy and Engineering, business.industry, Feedback circuits, Detector, Electrical engineering, Electrical and Electronic Engineering, Current (fluid), business, Engineering physics, Storage ring
Published
1981

17. Beam Energy Loss to Parasitic Modes in Spear II

Author

M. A. Allen, J. R. Rees, J. M. Paterson, and Perry B. Wilson

Subjects
Physics, Nuclear and High Energy Physics, Phase angle, Particle accelerator, law.invention, Acceleration, Nuclear Energy and Engineering, law, Physics::Accelerator Physics, Vacuum chamber, Electric potential, Electrical and Electronic Engineering, Atomic physics, Excitation, Beam (structure), Voltage
Abstract

The energy loss due to the excitation of parasitic modes in the SPEAR II rf cavities and vacuum chamber components has been measured by observing the shift in synchronous phase angle as a function of circulating beam current and accelerating cavity voltage. The resulting parasitic mode loss resistance is 5 M? at a bunch length of 6.5 cm. The loss resistance varies with bunch length ?z approximately as exp(-0.3 ?z). If the measured result is compared with reasonable theoretical predictions, we infer that the major portion of the parasitic loss takes place in ring vacuum components rather than in the rf cavities.

Published
1975

18. Initial measurements ofZ-boson resonance parameters ine+e−annihilation

Author

G. S. Abrams, C. E. Adolphsen, R. Aleksan, J. P. Alexander, M. A. Allen, W. B. Atwood, D. Averill, J. Ballam, P. Bambade, B. C. Barish, T. Barklow, B. A. Barnett, J. Bartelt, S. Bethke, D. Blockus, W. de Boer, G. Bonvicini, A. Boyarski, B. Brabson, A. Breakstone, M. Breidenbach, J. M. Brom, J. L. Brown, K. L. Brown, F. Bulos, P. R. Burchat, D. L. Burke, R. J. Cence, J. Chapman, M. Chmeissani, J. Clendenin, D. Cords, D. P. Coupal, P. Dauncey, N. R. Dean, H. C. DeStaebler, D. E. Dorfan, J. M. Dorfan, P. S. Drell, D. C. Drewer, F. Dydak, S. Ecklund, R. Elia, R. A. Erickson, J. Fay, G. J. Feldman, D. Fernandes, R. C. Field, T. H. Fieguth, G. E. Fischer, W. T. Ford, C. Fordham, R. Frey, D. Fujino, K. K. Gan, C. Gatto, E. Gero, G. Gidal, T. Glanzman, G. Goldhaber, J. J. Gomez Cadenas, G. Gratta, G. Grindhammer, P. Grosse-Wiesmann, G. Hanson, R. Harr, B. Harral, F. A. Harris, C. M. Hawkes, K. Hayes, C. Hearty, D. Herrup, C. A. Heusch, M. D. Hildreth, T. Himel, D. A. Hinshaw, S.-O. Holmgren, S. J. Hong, D. Hutchinson, A. Hutton, J. Hylen, W. R. Innes, R. G. Jacobsen, M. Jaffre, J. A. Jaros, R. K. Jobe, C. K. Jung, J. A. Kadyk, D. Karlen, J. Kent, M. King, S. R. Klein, D. S. Koetke, S. Komamiya, W. Koska, L. A. Kowalski, W. Kozanecki, J. F. Kral, M. Kuhlen, A. V. Kulikov, L. Labarga, A. J. Lankford, R. R. Larsen, F. Le Diberder, M. E. Levi, A. M. Litke, T. Lohse, V. Lüth, G. R. Lynch, J. A. McKenna, J. A. J. Matthews, T. Mattison, B. D. Milliken, K. C. Moffeit, C. T. Munger, J. J. Murray, W. N. Murray, J. Nash, H. Ogren, R. A. Ong, K. F. O’Shaughnessy, S. I. Parker, C. Peck, M. L. Perl, F. Perrier, A. Petersen, M. Petradza, N. Phinney, R. Pitthan, F. C. Porter, P. Rankin, J. R. Rees, J. D. Richman, K. Riles, L. Rivkin, M. C. Ross, F. R. Rouse, D. R. Rust, H. F. W. Sadrozinski, M. W. Schaad, T. L. Schalk, B. A. Schumm, A. S. Schwarz, J. T. Seeman, A. Seiden, J. C. Sheppard, J. G. Smith, A. Snyder, E. Soderstrom, R. Stiening, D. P. Stoker, R. Stroynowski, M. Swartz, R. Thun, N. Toge, G. H. Trilling, R. Van Kooten, P. Voruganti, S. R. Wagner, S. Watson, P. Weber, A. Weigend, A. J. Weinstein, A. J. Weir, S. L. White, E. Wicklund, R. C. Wolf, D. R. Wood, M. Woods, G. Wormser, R. Wright, D. Y. Wu, M. Yurko, C. Zaccardelli, and C. von Zanthier

Subjects
Physics, Particle physics, Partial width, Annihilation, Electron–positron annihilation, General Physics and Astronomy, Weinberg angle, Astrophysics::Cosmology and Extragalactic Astrophysics, Resonance (particle physics), Nuclear physics, High Energy Physics::Experiment, Astrophysics::Earth and Planetary Astrophysics, Neutrino, Nuclear Experiment, Astrophysics::Galaxy Astrophysics
Abstract

We have measured the mass of the Z boson to be 91.11±0.23 GeV/c^2, and its width to be 1.61-0.43+0.60 GeV. If we constrain the visible width to its standard-model value, we find the partial width to invisible decay modes to be 0.62±0.23 GeV, corresponding to 3.8±1.4 neutrino species.

Published
1989

19. Automatic Control Program for Spear

Author

N. Spencer, J. R. Rees, A. S. King, M. J. Lee, and A. M. Boyarski

Subjects
Nuclear and High Energy Physics, Engineering, Automatic control, business.industry, Electrical engineering, Electronic equipment, Linear particle accelerator, Power (physics), Set (abstract data type), Unison, Nuclear Energy and Engineering, Control system, Electrical and Electronic Engineering, Spear, business
Abstract

LO dr.i\ t’

Published
1973

21. The Design of Low-Beta Insertions for Storage Rings

Author

P. Morton and J. R. Rees

Subjects
Physics, Nuclear and High Energy Physics, Nuclear Energy and Engineering, Beta (plasma physics), Synchrotron radiation, Electron, Radio frequency, Electrical and Electronic Engineering, Atomic physics, Current density, Linear particle accelerator
Published
1967

22. Electron-Proton Elastic Scattering at 1 and 4 BeV

Author

John R. Dunning, W. Shlaer, Norman F. Ramsey, K. W. Chen, and J. R. Rees

Subjects
Nuclear physics, Physics, Elastic scattering, Photon, Proton, Scattering, Form factor (quantum field theory), General Physics and Astronomy, Elementary particle, Electron, Atomic physics, Electric charge
Abstract

The cross section was measured at forward electron angles to detect possible deviations from the Rosenbluth formula. Data were obtained at 4-Bev incident electron energy with q/sup 2/ = 6, 10, 14, and 18 F/sup -2/, and at 1 Bev with q/sup 2/ = 6, 10, and 14 F/sup -2/. The results are consistent with a photon Regge trajectory of zero slope. A core term is indicated in the values of the proton's charge form factor extracted from the 4-Bev data. (auth)

Published
1963

24. The Tasks of Psychiatry

Author

J. R. Rees

Subjects
medicine.medical_specialty, medicine, General Medicine, Psychology, Psychiatry
Abstract

It is perhaps of some small interest that the President of the Section of Neurology delivered last week in this building an address on “The Borders of Neurology,” and that for to-night I had chosen to speak on what is obviously a related topic, the “Tasks of Psychiatry.” It is, of course, possible that behind this choice of our titles there may simply be a geriatric problem, for the President of the Section of Neurology and I worked together as members of the same Field Ambulance in the Battle of the Somme, just over 32 years ago. On the other hand, there may be more than this in it, and perhaps we really do need to define our fields rather more clearly and to make sure what our tasks are, and how we are best to meet them. In fact, I think that the question of the actual borders of psychiatry, as apart from its tasks, was dealt with quite convincingly in the Joint Report of the Royal College of Physicians, the B. M. A. Psychological Medicine Group and the Royal Medico-Psychological Association.

Published
1949

25. The Thirty-First Maudsley Lecture: Psychiatry and Public Health

Author

J. R. Rees

Subjects
Psychiatry, medicine.medical_specialty, business.industry, Public health, 05 social sciences, General Medicine, 050108 psychoanalysis, 050105 experimental psychology, Humans, Medicine, 0501 psychology and cognitive sciences, Public Health, business
Abstract

When the Council greatly honoured me by their invitation to be the Maudsley Lecturer for 1956, my first concern was as to what subject I could choose for my remarks.

Published
1957

26. ACCIDENTAL HYPOTHERMIA

Author

J R, REES

Subjects
Anesthesiology and Pain Medicine, Hypothermia, General Medicine, Body Temperature
Published
1958

27. Electroproduction of Protons at 1 and 4 BeV

Author

K. W. Chen, J. K. Walker, John R. Dunning, Richard Wilson, W. Shlaer, and J. R. Rees

Subjects
Physics, Nuclear physics, Particle physics, Angular distribution, Particle model, General Physics and Astronomy
Published
1964

29. Myocardial blood flow measurement with 133-Xenon effect of glyceryl trinitrate in dogs

Author

J R Rees, C J Gavey, D Gibson, R Ashfield, and V J Redding

Subjects
medicine.medical_specialty, Xenon, business.industry, Myocardium, chemistry.chemical_element, Blood flow, Coronary Vessels, Nitroglycerin, Blood, Dogs, chemistry, Internal medicine, Anesthesia, medicine, Cardiology, Animals, Oximetry, Cardiology and Cardiovascular Medicine, business, Blood Flow Velocity, Research Article, medicine.drug
Published
1966

30. Operating Results from SPEAR

Author

M. A. Allen, R. R. Larsen, W. Davies-White, A. P. Sabersky, J. R. Rees, J. Harris, G. E. Fischer, H. Wiedemann, P. Morton, R. Scholl, M. J. Lee, R. A. McConnell, A. M. Boyarski, J. Voss, J. E. Augustin, J. M. Paterson, Burton Richter, L. G. Karvonen, and N. Dean

Subjects
Physics, Nuclear and High Energy Physics, Luminosity (scattering theory), business.industry, Instability, Linear particle accelerator, Optics, Nuclear Energy and Engineering, Physics::Accelerator Physics, Electrical and Electronic Engineering, Chromaticity, Spear, Charged particle beam, business, Beam (structure), Storage ring
Abstract

Initial operating experience with the SLAC electron-positron storage ring SPEAR is described. A luminosity of 1.2 × 1031 cm-2 sec-1 has been achieved and two-beam interaction effects are described. A single-beam coherent instability, which can be suppressed either by control of the ring chromaticity or by feedback, has been observed. Current-dependent bunch lengthening and widening have been observed, and experiments indicate that these phenomena may be associated with an increase in the energy spread of the beam. Procedures to increase the luminosity to the design value are discussed. Plans to increase the maximum beam energy of SPEAR to 4.5 GeV are described.

Published
1973

33. Case of Conn's Syndrome

Author

J. R. Rees, D. Marrack, and P. K. M. Barrett

Subjects
medicine.medical_specialty, Pediatrics, Aldosterone, business.industry, General Engineering, Articles, General Medicine, Conn's syndrome, chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, Hyperaldosteronism, medicine, Humans, General Earth and Planetary Sciences, business, General Environmental Science
Published
1959

34. 5- to 16-GeV Single-π+Photoproduction from Hydrogen

Author

J. R. Rees, G. E. Fischer, Burton Richter, S. D. Ecklund, F. Bulos, A. M. Boyarski, R. Diebold, and W. Busza

Subjects
Scattering cross-section, Physics, Momentum, Photon, Pion, Hydrogen, chemistry, Momentum transfer, General Physics and Astronomy, chemistry.chemical_element, Neutron, Atomic physics
Abstract

The differential cross sections for single-${\ensuremath{\pi}}^{+}$ photoproduction from hydrogen have been measured over a range of momentum transfers from -2\ifmmode\times\else\texttimes\fi{}${10}^{\ensuremath{-}4}$ to -2 ${(\mathrm{G}\mathrm{e}\mathrm{V}/\mathit{c})}^{2}$, and photon energies from 5 to 16 GeV. The differential cross section increases by roughly a factor of 2 as the magnitude of the square of the momentum transfer decreases from 0.02 ${(\mathrm{G}\mathrm{e}\mathrm{V}/\mathit{c})}^{2}$. The cross section falls approximately as $\mathrm{exp}(\ensuremath{-}3|t|)$ at large momentum transfers, with a similar momentum-transfer dependence of the cross section at all photon energies studied.

Published
1968

35. Fatal fungal infection following open-heart surgery

Author

W. R. Lee, J. R. Rees, and S. W. B. Newsom

Subjects
Adult, Extracorporeal Circulation, medicine.medical_specialty, Heart Diseases, business.industry, Extracorporeal circulation, Candidiasis, MEDLINE, Aortic Valve Stenosis, Aortic Aneurysm, Culture Media, Surgery, Postoperative Complications, Thromboembolism, Humans, Medicine, Female, Serologic Tests, Cardiac Surgical Procedures, Cardiology and Cardiovascular Medicine, business, Research Article
Published
1967

36. The warm ischaemic time of the canine heart

Author

J. R. Rees, A. C. Branfoot, M. J. Pemberton, J. S. Bailey, P. A. Cullum, and V. J. Redding

Subjects
Extracorporeal Circulation, medicine.medical_specialty, Time Factors, Physiology, Ischemia, Blood Pressure, Coronary Disease, Coronary disease, Canine heart, Electrocardiography, Dogs, Oxygen Consumption, Physiology (medical), Internal medicine, medicine, Animals, cardiovascular diseases, medicine.diagnostic_test, business.industry, Myocardium, Extracorporeal circulation, Temperature, medicine.disease, Left ventricular end-diastolic pressure level, Blood pressure, Anesthesia, Heart Arrest, Induced, Hemoglobinometry, Potassium, Cardiology, Cardiology and Cardiovascular Medicine, business
Abstract

The safe limit of normothermic arrest of the canine heart, after which marked deterioration in function occurs, is investigated in the intact animal, using restricted bypass support. The results show a distinct difference between two groups of dogs with 30 and 60 min warm ischaemia respectively, which is primarily reflected in the ability to sustain the circulation, and also in the electrocardiogram, left ventricular end-diastolic pressure, and the rate of oxygen consumption.

Published
1970

37. PEP Lattice Design

Author

Lloyd H. Smith, A. Garren, J. R. Rees, P. Morton, and R. Bangerter

Subjects
Superconductivity, Physics, Nuclear and High Energy Physics, Proton, Astrophysics::High Energy Astrophysical Phenomena, Electron, Linear particle accelerator, Nuclear physics, Positron, Nuclear Energy and Engineering, Lattice (order), Physics::Accelerator Physics, High Energy Physics::Experiment, Radio frequency, Electrical and Electronic Engineering, Atomic physics, Nuclear Experiment, Storage ring
Abstract

Details of the current lattice design for PEP, the proton-electron-positron colliding beam system will be described. This system allows collisions of protons up to 150 GeV with electrons or positrons up to 15 GeV, by storing the proton beams in a superconducting storage ring and the electrons or positrons in a concentric conventional ring, and allows collisions between electrons and positrons in the same ring up to 15 GeV.

Published
1973

38. Recent Ideas on Upgrading the SLAC Accelerator

Author

R. Helm, G. A. Loew, Roger H. Miller, W. B. Herrmannsfeldt, J. R. Rees, R. B. Neal, C. W. Olson, and J. V. Lebacqz

Subjects
Physics, Nuclear and High Energy Physics, Klystron, business.industry, RF power amplifier, Electrical engineering, Particle accelerator, Linear particle accelerator, law.invention, Nuclear Energy and Engineering, law, Duty cycle, Radio frequency, Electrical and Electronic Engineering, business, Storage ring, Beam (structure)
Abstract

In June 1971, the SLAC accelerator will have completed its first five years of operation. The machine has recently achieved records of energy (22.1 GeV), peak beam current (82 mA at a 1.6 ..mu..s pulse length) and average beam power (880 kW). The demand for major accelerator innovations and improvements is becoming increasingly strong. Some of the recent ideas on this subject are summarized. There are a variety of options, and these can be divided into three categories: (a) improvements and upgrading of the existing linac; (b) energy and duty cycle increases by means of beam storage in a recirculation scheme, and (c) various colliding beam devices. The first category includes increasing beam energy by addition of rf power or increasing duty cycle by modifying the modulators; it also includes an rf monochromatizer which could sharpen energy spectrum by a factor of 30. The second category involves a scheme which would increase beam energy by ''storing'' the electrons in a recirculator until they can be re-injected and reaccelerated by the accelerator a second time. The third category comprises the possibility of colliding the linac beam with the beams stored in the SLAC storage ring (SPEAR) or of colliding the linacmore » beam with itself.« less

Published
1971

40. HAeMODYNAMIC EFFECTS OF SEVERE AORTIC REGURGITATION

Author

E. J. Epstein, R. S. Ross, J. M. Criley, and J. R. Rees

Subjects
medicine.medical_specialty, Aortic Valve Insufficiency, Hemodynamics, Blood Pressure, Cardiomegaly, Regurgitation (circulation), Aortic Coarctation, Angina Pectoris, Electrocardiography, Internal medicine, Humans, Medicine, medicine.diagnostic_test, business.industry, Angiography, Articles, Dyspnea, Blood pressure, Hypertension, Cardiology, Heart enlargement, Cardiology and Cardiovascular Medicine, business
Published
1964

41. Psychology and Massage

Author

J. R. Rees

Subjects
Massage, Psychotherapist, Physical Therapy, Sports Therapy and Rehabilitation, Psychology
Published
1930

42. Proton-Electron-Positron Design Study

Author

H. Weidemann, E.C. Hartwig, Lloyd H. Smith, R. Bangerter, L. Stevenson, J. E. Augustin, P. Morton, A. Garren, M. J. Lee, V. K. Neil, T. Elioff, Burton Richter, Tom Elioff, S. Berman, William A. Wenzel, R. Sah, E. Close, Robert T. Avery, M. A. Allen, Andrew M. Sessler, W. Gilbert, and J. R. Rees

Subjects
Accelerator physics, Physics, Nuclear and High Energy Physics, Proton, Authorization, Particle accelerator, Electron, law.invention, Nuclear physics, Positron, Nuclear Energy and Engineering, law, Design study, Electrical and Electronic Engineering, Collider
Published
1973

43. Components of weight loss in obese patients subjected to prolonged starvation

Author

W T Stubenbord, B Thorbjarnarson, R Macfarlane, J W Asaph, G M Watkins, W R Grafe, G N Cornell, H Gilder, and J R Rees

Subjects
Male, medicine.medical_specialty, Nitrogen balance, Diet, Reducing, Nitrogen, Physiology, Body water, Calorimetry, Oxygen Consumption, Weight loss, Physiology (medical), Internal medicine, medicine, Humans, Obesity, Starvation, business.industry, Metabolism, Carbon Dioxide, medicine.disease, Oxygen, Endocrinology, Adipose Tissue, Female, medicine.symptom, business, Blood Chemical Analysis
Published
1967

44. Operation of the PEP Transverse Beam Feedback

Author

J. R. Rees, C. W. Olson, J.-L. Pellegrin, and J. M. Paterson

Subjects
Physics, Nuclear and High Energy Physics, business.industry, Amplifier, Feedback loop, Signal, Optics, Bunches, Nuclear Energy and Engineering, Control theory, Harmonic, Physics::Accelerator Physics, Electrical and Electronic Engineering, business, Frequency modulation, Storage ring, Beam (structure)
Abstract

The PEP Storage Ring has been equipped with a wide band beam feedback system capable of damping the vertical and horizontal motion of six bunches. The oscillation detection is done at a symmetry point on the Storage Ring and feedback is applied at the same location one orbital period later. The signal is synchronously gated and the system appears as twelve independent feedback loops, operating on the two coordinates of each of the six bunches. Two beam deflection electrodes are driven each by a low-Q push-pull amplifier which is tuned at the 72nd harmonic of the revolution frequency and suppressed-carrier modulation is generated by a sequence of the detected bunch oscillations. The design parameters are reviewed as well as the salient features of the hardware, and the impact of this system on the machine operation is evaluated in the light of experimental results.

Published
1981

45. Single Feedback Systems for Simultaneous Damping of Horizontal and Longitudinal Coherent Oscillations

Author

P. Morton, Alex Chao, and J. R. Rees

Subjects
Physics, Nuclear and High Energy Physics, Mathematical model, Equations of motion, Measure (mathematics), Power (physics), Nuclear Energy and Engineering, Position (vector), Control theory, Trajectory, Physics::Accelerator Physics, Radio frequency, Electrical and Electronic Engineering, Matrix method
Abstract

To describe the horizontal motion of the bunch, we need four coordinates, x and z are the horizontal and longitudinal displacements of the bunch center relative to the ideal trajectory; x' is the angle between the bunch's direction of motion and the ideal trajectory; and delta=..delta..E/E is relative energy error of the bunch. Among the four variables, x and z are easy to measure by position monitors, while x' and delta are easy to change by electromagnetic devices. In combination, this suggests four possible types of feedback systems. In the following, we will present a complete analysis of the Type (x, delta) feedback system, using a matrix method. The analyses of other types are similar to that of Type (x, delta) and only the results are included. We then include some comparisons of these types of feedback schemes in terms of power consumptions and the effectiveness in damping the horizontal-betatron and synchrotron oscillations. We will also discuss some effects of position measuring errors on the performance of the feedback system. 2 refs., 3 tabs.

Published
1979

46. Recent Improvements in Luminosity at PEP

Author

J. R. Rees, Burton Richter, Perry B. Wilson, Alex Chao, T. W. Martin, James E. Spencer, M. A. Allen, J.T. Seeman, Robert J. Miller, P. Morton, M. Donald, S. Kheifets, H. Shoaee, H. Wiedemann, R. Helm, J. M. Paterson, and L. Rivkin

Subjects
Physics, Nuclear and High Energy Physics, Optics, Nuclear Energy and Engineering, business.industry, Physics::Accelerator Physics, Optical noise, High Energy Physics::Experiment, Astrophysics, Electrical and Electronic Engineering, business
Abstract

We will describe improvements which have led to new records for peak and average luminosity at PEP. Comparison of recent results with several earlier lattice and optical modifications shows rather good correlation with the predictions of a beam-beam simulation program.

Published
1983

47. Enalapril for Congestive Heart Failure

Author

K. L. Swedberg Wilhelmsen, M. Packer, J. Zatuchni, J. R. Rees, T. Rogers, Al Hallstrom, K. S. Channer, C. S. Maskin, J. H. Meyer, J. Kjekshus, M. J. Gillespie, L. G. Dennick, C. J C Roberts, W. E. Schotz, E. R. Squibb, and B. W. Brown

Subjects
medicine.medical_specialty, business.industry, Heart failure, Internal medicine, Cardiology, Medicine, General Medicine, Enalapril, business, medicine.disease, medicine.drug
Published
1987

48. PSYCHIATRY IN THE BRITISH ARMY

Author

Brigadier J. R. Rees

Subjects
Psychiatry and Mental health, medicine.medical_specialty, business.industry, Medicine, business, Psychiatry
Published
1944

50. THE GENERAL PRACTITIONER AND MENTAL CONDITIONS

Author

J. R. Rees

Subjects
Text mining, business.industry, General Engineering, General Earth and Planetary Sciences, Medicine, Articles, General Medicine, business, Data science, General Environmental Science
Published
1935

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