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Introduction COVID-19 associated severe acute respiratory syndrome rapidly progress to irreversible lung injury, multiple organ failure and death. Lung transplantation is considered as the rescue therapy for these patients. Herein, we reported a case series of two successful life-saving bilateral lung transplantations for COVID-19-associated respiratory failure. Case Report Case 1: A 69-year-old male was admitted for hypoxia and altered mental status. He was diagnosed with COVID-19 pneumonia by abnormal CT findings and positive PCR result. After receiving a course of dexamethasone, convalescent plasma, remdesivir and broad-spectrum antibiotics, he remained to be profoundly hypoxic, requiring non-invasive ventilation. Following two negative PCR results, he underwent bilateral lung transplantation on day 57. He was discharged to rehab unit on postoperative day 26. No desaturation was observed with the 6-min walk test on 30-day follow-up. Case 2: A 63-year-old male was presented with cough, and dyspnea. He was hemodynamically stable, SpO2 was 94%, chest x-ray was normal and tested positive for COVID-19. He was discharged home with dexamethasone and bronchodilators. However, he presented back on day 6 with worsening dyspnea. He was admitted and received a course of dexamethasone, remdesivir, convalescent plasma and broad-spectrum antibiotics. Due to persistent hypoxic respiratory failure, the patient underwent bilateral orthotopic lung transplantation on day 68. His postoperative course was complicated by primary graft dysfunction stage 3 and required open tracheostomy. His condition gradually improved and decannulated. He is currently on room air and able to walk 30 ft using a roller walker. Summary SARS-CoV-2 recovery is characterized by post inflammatory fibrosis and multi organ dysfunction. Lung transplantation can be successfully performed in patients with final stage respiratory failure of COVID-19 related pulmonary fibrosis.

The study was undertaken on 11 Surti male kids of identical age and birth weight from 14 weeks of age till puberty and sexual maturity up to 47 weeks (12 months) of age. The scrotal biometry, i.e., length, width, circumference (cm) and volume (cm3) were recorded using standard procedures at 3 weeks intervals. The mean weight of animals at birth, 14 and 35 weeks of age was 1.53±0.05, 9.86±0.61 kg and 17.84±1.09 kg, respectively and thereafter it did not change much till 47 weeks of age. Similarly, the mean values of scrotal length, width, circumference (cm) and scrotal volume (cm3) at 14 weeks of age were 2.89±0.22, 2.05±0.17, 8.82±0.72 and 21.36±0.93, respectively, which then gradually increased with an advancing age till 35 weeks of age reaching 10.65±0.30, 7.55±0.24, 19.45±0.65 and 200.45±16.67, respectively, which later became almost stable. At puberty, the average age and body weight were 27.00±0.75 weeks and 15.16±0.56 kg, and at sexual maturity 38.18±0.90 weeks and 19.61±0.93 kg, respectively. Great individual variation was noted in all the biometric traits among bucks studied. The blood plasma profile studied at bimonthly intervals revealed significant increase in total protein and ALT, and decrease in cholesterol and cobalt concentrations with advancing age. However, the AST and macro-micro minerals did not vary, suggestive of acquiring adult profile by 6 months of age. Based on the age, scrotal biometry, semen quality and blood biochemistry, it could be inferred that the Surti bucks attained full reproductive potential at around 9- 10 months of age with stable blood plasma profile.

Geomagnetically induced current (GIC) is harmful to the power system mainly on the transformer. Also, it causes serious problems to the transformers. It is DC bias current produced due to the effect of solar storm on earth. As GIC enter in the transformer through neutral wire it will lead to saturation of the transformer core. It produces harmonics in the power system. Due to saturation and harmonics, heating of transformer cores, burning of windings and miss operation of protective devices may occur. This paper presents the analysis of GIC effects in transformer's performance.

The Geomagnetically induced current (GIC) produces unwanted adverse consequences in the power system. It causes problems in the power system like transformer core saturation, really miss operation, blackout of system, voltage instability and heating of transformers, disturbance in communication systems, corrosion of pipelines, railway tracks etc. This paper provides information about GIC and its different effects in various technological systems. Also present the possible solution to reduce GIC.

Lymph node status remains the most important prognostic indicator for breast cancer. Recent reports have established that the accuracy of assessing lymph node status is proportional to the number of nodes dissected. The accuracy of axillary staging following neoadjuvant chemotherapy has been cited as a technical concern due to limited node retrieval. The current study attempts to evaluate the ability to perform sentinel node biopsy (SNB) and formal axillary node dissection (AND) following neoadjuvant chemotherapy and to compare these results with non-neoadjuvant patients. One hundred sixteen consecutive patients undergoing SNB with simultaneous AND were retrospectively reviewed. Forty-two of these patients were treated with neoadjuvant chemotherapy prior to AND. Overall success rate in performing SNB in the neoadjuvant group was 95 per cent, and no false negatives have been noted to date. The overall SNB success rate in the non-neoadjuvant group was also 95 per cent with a false negative rate of 3 per cent. After AND in each group, a mean of 21 nodes were retrieved in the neoadjuvant group and 17.9 nodes in the non-neoadjuvant group ( P = 0.018). In the neoadjuvant group, there were 19 node positive patients (42%) and 21 patients (28%) in the non-neoadjuvant group ( P = 0.16). The mean number of positive nodes per patient was also similar between the two groups (2.9 in the neoadjuvant group vs 1.67 in the non-neoadjuvant group, P = 0.10). Following neoadjuvant therapy, accurate evaluation of the axilla is feasible. In this study, the mean number of nodes is significantly different in favor of the neoadjuvant group, but there is no significant difference in the number of node positive patients identified or in the mean number of positive nodes identified per patient. SNB is technically feasible with accuracy similar to that seen in patients with no history of neoadjuvant therapy. Neoadjuvant chemotherapy extends the use of breast-conserving therapy without sacrificing the ability to accurately stage the axilla either by use of standard axillary dissection or SNB.

A subjective assessment of fork-lift truck seats has been carried out to assess the range of preferred seat dimensions and the acceptability of different seat adjustments to fork-lift truck drivers. Twelve fork-lift truck seats fitted to a fixed bench were assessed by twelve fork-lift truck drivers. For each seat, each driver completed a questionnaire that covered the following areas: eleven seat dimensions, four seat adjustments and other features (arm rests, safety belts and safety wings). The drivers assessed the dimensions of a seat chosen at random, before moving to the adjacent seat in either a clockwise or anticlockwise direction. Before each assessment, they were asked to look forward and backward in the seat as though they were driving a fork-lift truck. In general, significant correlations were obtained between the subjective assessments and objective measurements of the seat dimensions. This enabled preferred seat dimension ranges to be defined. Fork-lift truck drivers ranked the forward-backward and the backrest inclination adjustments as most important. The results showed that although the drivers had previous experience in the use of suspension seats, they did not understand the purpose of the weight adjustment. All adjustments should be easy to find, accessible, easy to move and they should enable a range of adjustments. In addition, clear and simple information on the seat is needed, especially for the weight adjustment. The most recently designed seats generally had dimensions within the preferred ranges compared with the older generation seats, mainly because they had more adjustments. However, the results show that adjustments on fork-lift truck seats could be improved further. Some tentative conclusions are made for the preferred fork-lift truck seat dimensions and adjustment ranges which are based on the evidence from this restricted sample of fork-lift truck drivers. They may be useful for seat and truck designers in the preparation of a standard on fork-lift truck seat dimensions.