This study aimed to evaluate the influence of organomineral fertilizer on the growth and mineral composition of Moringa oleifera organs. The experiment included three doses of cow dung, three doses of mineral fertilizers and two doses combining mineral fertilizers and cow dung. Soil samples and samples of M. oleifera organs were analyzed. Results revealed the contribution of fertilizer to improve soil chemical properties, except pH. The best vegetative development was obtained with the dose of 125 kg of mineral fertilizers per hectare. However, the mineral composition of Moringa oleifera has been improved by the application of organic matter compared to mineral fertilizers. In the second year of harvest, the results showed that the young leaves of Moringa are rich in moisture and ash, whereas mature leaf, have high levels of lipid, cellulose and proteins compared to young leaves. In the context of poor nutrition, Moringa oleifera L. is a sustainable solution when grown organically.