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Your search keyword '"J.P. Le Floch"' showing total 2 results
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2 results on '"J.P. Le Floch"'

1. Predicting factors of hypoglycaemia in elderly type 2 diabetes patients: Contributions of the GERODIAB study

Author

L. Bordier, M. Buysschaert, B. Bauduceau, J. Doucet, C. Verny, V. Lassmann Vague, J.P. Le Floch, B Bauduceau, J-F Blicklé, I Bourdel-Marchasson, T Constans, J Doucet, A Fagot-Campagna, E Kaloustian, V Lassmann-Vague, P Lecomte, D Tessier, C Verny, U Vischer, H Affres, M Alix, F Archambeaud, Z Barrou, P Beau, S Beltran, C Benoit, J-P Beressi, F Bernachon, C Berne, G Berrut, A Blaimont, J-F Blickle, M Boda-Buccino, J Bohatier, P Böhme, L Bordier, K Bouchou, B Bouillet, F Bouilloud, R Bouix, E Boulanger, C Bourgon, E Bourrinet, P Brocker, I Bruckert, C Capet, C Carette, B Cariou, A Carreau, C Chaillou Vaurie, S Chamouni, C Ciangura, C Collet-Gaudillat, M-E Combes-Moukhovsky, M Cordonnier, A Cuperlier, D Dambre, J D'Avigneau, P De Botton, V Degros, F Delamarre-Damier, S Denat, F Desbiez, B Deumier, F Dorey, E Dresco, A Drutel, E Du Rosel De Saint Germain, D Dubois-Laforgue, B Duly-Bouhanick, O Dupuy, L Dusselier, S Faucher-Kareche, S Fendri, P Fontaine, S Galinat, A Gentric, H Gin, F Glaise, T Godeau, B Gonzales, I Got, B Guerci, P-J Guillausseau, S Hadjadj, Y Hadjali, M Halbron, S Halimi, C Halter, H Hanaire, V Hardy, A Hartemann-Heurtier, J-P Haulot, F Hequet, M Issa-Sayegh, P Jan, N Jeandidier, H Joseph-Henri, I Julier, V Kerlan, T Kharitonnoff, M Ladsous, L Lahaxe, M-P Lamaraud, E Lassenne, J-M Lecerf, I Leroux, S Lesven, M Levy, S Lopez, F Makiza, P Manckoundia, C Marquis Pomeau, H Mayaudon, S Micheli, R Mira, F Monnier, H Mosnier-Pudar, N Neri, I Normand, M Paccalin, C Pagu, D Paris, A Penfornis, J-L Perie, J-M Petit, G Petit-Aubert, B Pichot-Duclos, L Pivois, M Popelier, G Poulingue, M Priner, V Quipourt, M Rasamisoa, J-L Richard, V Rigalleau, N Roudat, C Sanz, J-M Serot, D Sifi, S Sirvain, A Slimani, E Sonnet, C Sosset, A Soualah, A Stroea, I Tauveron, J Timsit, M Tschudnowsky, A Vambergue, O Verier-Mine, and M Virally

Subjects
Pediatrics, medicine.medical_specialty, endocrine system diseases, Depression scale, Endocrinology, Diabetes and Metabolism, Population, Type 2 diabetes, Severity of Illness Index, Endocrinology, Risk Factors, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Multicenter Studies as Topic, education, Geriatric Assessment, Aged, Aged, 80 and over, Ldl cholesterol, education.field_of_study, Depression, business.industry, nutritional and metabolic diseases, General Medicine, Prognosis, medicine.disease, Survival Analysis, Hypoglycemia, Surgery, Diabetes Mellitus, Type 2, Ageing, Observational study, Morbidity, business, Retinopathy
Abstract

The burden of hypoglycaemia is important, particularly in elderly type 2 diabetes (T2D) patients. Unfortunately, however, few studies are available concerning this population. GERODIAB is a prospective, multicentre, observational study that aims to describe the 5-year morbidity and mortality of 987 T2D patients aged 70 years and older. After analyzing the frequency of and factors associated with hypoglycaemia in the 6 months prior to study inclusion, it was found that hypoglycaemia was associated with retinopathy, lower levels of LDL cholesterol and altered mini-Geriatric Depression Scale (GDS) scores.

Published
2015
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2. Handedness, immune disorders and information bias

Author

A. Kahan, Georges Dellatolas, M.F. Kahn, Michel Chavance, M.G. Bousser, J.P. Le Floch, G. Tchobroutsky, B. Amor, and B. Grardel

Subjects
Adult, Male, Cognitive Neuroscience, Migraine Disorders, Population, Experimental and Cognitive Psychology, Disease, Functional Laterality, Developmental psychology, Autoimmune Diseases, Behavioral Neuroscience, Bias, Risk Factors, Immunopathology, medicine, Humans, Lupus Erythematosus, Systemic, Information bias, education, education.field_of_study, Case-control study, Middle Aged, medicine.disease, Graves Disease, Diabetes Mellitus, Type 1, Migraine, Case-Control Studies, Laterality, Conviction, Female, Psychology, Clinical psychology
Abstract

In order to investigate the relations between handedness and migraine or immune disorders, we performed a case control study comparing the handedness of patients suffering from systemic lupus erythematosus (SLE), type I diabetes, Graves' disease, or migraine to that of a random sample of controls from the general population. A handedness index was measured from a 10-item questionnaire. No significant difference was observed. But when the controls who denied having ever suffered from migraine or any allergic disease were set apart from those who gave at least one positive answer to the same questions, the former were found more right-handed, i.e. with a lower handedness index than the latter (P less than 0.05) and than the SLE patients (P less than 0.05). More generally, the mean observed handedness index of controls giving a positive answer to any question about their health was found repeatedly higher than that of controls giving a negative answer: this was observed for 27 of the 32 questions. These results are highly suggestive of an information bias, the subjects saying they use the right hand for each of the 10 activities considered in the questionnaire being more likely to deny having suffered from a given disease or used, more or less recently, some drug or medical service. Our conviction is that previous observations dealing with the same topic are also more easily explained by the presence of an information bias than by Geschwind's theory. The implications for the design of further epidemiologic studies are discussed.

Published
1990

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