159 results on '"Jacob, X."'
Search Results
2. Infrared light elicits endothelium-dependent vasodilation in isolated occipital arteries of the rat via soluble guanylyl cyclase-dependent mechanisms
- Author
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Tristan H. J. Lewis, Junqi Zhuo, Jacob X. McClellan, Paulina M. Getsy, Rita M. Ryan, Michael. J. Jenkins, and Stephen J. Lewis
- Subjects
infrared light ,occipital arteries ,endothelium-dependent vasodilation ,nitric oxide ,soluble guanylate cyclase ,Physiology ,QP1-981 - Abstract
The left and right occipital arteries provide blood supply to afferent cell bodies in the ipsilateral nodose and petrosal ganglia. This supply is free of an effective blood-ganglion barrier, so changes in occipital artery blood flow directly affect the access of circulating factors to the afferent cell bodies. The application of infrared (IR) light to modulate neural and other cell processes has yielded information about basic biological processes within tissues and is gaining traction as a potential therapy for a variety of disease processes. To address whether IR can directly modulate vascular function, we performed wire myography studies to determine the actions of IR on occipital arteries isolated from male Sprague-Dawley rats. Based on our previous research that functionally-important differences exist between occipital artery segments close to their origin at the external carotid artery (ECA) and those closer to the nodose ganglion, the occipital arteries were dissected into two segments, one closer to the ECA and the other closer to the nodose ganglion. Segments were constricted with 5-hydroxytryptamine to a level equal to 50% of the maximal response generated by the application of a high (80 mM) concentration of K+ ions. The direct application of pulsed IR (1,460 nm) for 5 s produced a rapid vasodilation in occipital arteries that was significantly more pronounced in segments closest to the ECA, although the ECA itself was minimally responsive. The vasodilation remained for a substantial time (at least 120 s) after cessation of IR application. The vasodilation during and following cessation of the IR application was markedly diminished in occipital arteries denuded of the endothelium. In addition, the vasodilation elicited by IR in endothelium-intact occipital arteries was substantially reduced in the presence of a selective inhibitor of the nitric oxide-sensitive guanylate cyclase, 1H-[1,2,4]oxadiazolo [4,3-a]quinoxalin-1-one (ODQ). It appears that IR causes endothelium-dependent, nitric-oxide-mediated vasodilation in the occipital arteries of the rat. The ability of IR to generate rapid and sustained vasodilation may provide new therapeutic approaches for restoring or improving blood flow to targeted tissues.
- Published
- 2023
- Full Text
- View/download PDF
3. In situ recording of Mars soundscape
- Author
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Maurice, S., Chide, B., Murdoch, N., Lorenz, R. D., Mimoun, D., Wiens, R. C., Stott, A., Jacob, X., Bertrand, T., Montmessin, F., Lanza, N. L., Alvarez-Llamas, C., Angel, S. M., Aung, M., Balaram, J., Beyssac, O., Cousin, A., Delory, G., Forni, O., Fouchet, T., Gasnault, O., Grip, H., Hecht, M., Hoffman, J., Laserna, J., Lasue, J., Maki, J., McClean, J., Meslin, P.-Y., Le Mouélic, S., Munguira, A., Newman, C. E., Rodríguez Manfredi, J. A., Moros, J., Ollila, A., Pilleri, P., Schröder, S., de la Torre Juárez, M., Tzanetos, T., Stack, K. M., Farley, K., and Williford, K.
- Published
- 2022
- Full Text
- View/download PDF
4. The sound of a Martian dust devil
- Author
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Murdoch, N., Stott, A. E., Gillier, M., Hueso, R., Lemmon, M., Martinez, G., Apéstigue, V., Toledo, D., Lorenz, R. D., Chide, B., Munguira, A., Sánchez-Lavega, A., Vicente-Retortillo, A., Newman, C. E., Maurice, S., de la Torre Juárez, M., Bertrand, T., Banfield, D., Navarro, S., Marin, M., Torres, J., Gomez-Elvira, J., Jacob, X., Cadu, A., Sournac, A., Rodriguez-Manfredi, J. A., Wiens, R. C., and Mimoun, D.
- Published
- 2022
- Full Text
- View/download PDF
5. Multi-instrumentation monitoring for the curing process of a composite structure
- Author
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Collombet, F., Torres, M., Douchin, B., Crouzeix, L., Grunevald, Y.-H., Lubin, J., Camps, T., Jacob, X., Luyckx, G., and Wu, K.-T.
- Published
- 2020
- Full Text
- View/download PDF
6. Origin of a Non-Clarke's Column Division of the Dorsal Spinocerebellar Tract and the Role of Caudal Proprioceptive Neurons in Motor Function.
- Author
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Yuengert, Rachel, Hori, Kei, Kibodeaux, Erin E, McClellan, Jacob X, Morales, Justin E, Huang, Teng-Wei P, Neul, Jeffrey L, and Lai, Helen C
- Subjects
Medulla Oblongata ,Cerebellum ,Afferent Pathways ,Neurons ,Afferent ,Animals ,Mice ,Inbred C57BL ,Mice ,Proprioception ,Cell Lineage ,Movement ,Female ,Male ,Basic Helix-Loop-Helix Transcription Factors ,Neurogenesis ,Neural Stem Cells ,Spinal Cord Dorsal Horn ,Biochemistry and Cell Biology - Abstract
Proprioception, the sense of limb and body position, is essential for generating proper movement. Unconscious proprioceptive information travels through cerebellar-projecting neurons in the spinal cord and medulla. The progenitor domain defined by the basic-helix-loop-helix (bHLH) transcription factor, ATOH1, has been implicated in forming these cerebellar-projecting neurons; however, their precise contribution to proprioceptive tracts and motor behavior is unknown. Significantly, we demonstrate that Atoh1-lineage neurons in the spinal cord reside outside Clarke's column (CC), a main contributor of neurons relaying hindlimb proprioception, despite giving rise to the anatomical and functional correlate of CC in the medulla, the external cuneate nucleus (ECu), which mediates forelimb proprioception. Elimination of caudal Atoh1-lineages results in mice with relatively normal locomotion but unable to perform coordinated motor tasks. Altogether, we reveal that proprioceptive nuclei in the spinal cord and medulla develop from more than one progenitor source, suggesting an avenue to uncover distinct proprioceptive functions.
- Published
- 2015
7. Author Correction: In situ recording of Mars soundscape
- Author
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Maurice, S., Chide, B., Murdoch, N., Lorenz, R. D., Mimoun, D., Wiens, R. C., Stott, A., Jacob, X., Bertrand, T., Montmessin, F., Lanza, N. L., Alvarez-Llamas, C., Angel, S. M., Aung, M., Balaram, J., Beyssac, O., Cousin, A., Delory, G., Forni, O., Fouchet, T., Gasnault, O., Grip, H., Hecht, M., Hoffman, J., Laserna, J., Lasue, J., Maki, J., McClean, J., Meslin, P.-Y., Le Mouélic, S., Munguira, A., Newman, C. E., Rodríguez Manfredi, J. A., Moros, J., Ollila, A., Pilleri, P., Schröder, S., de la Torre Juárez, M., Tzanetos, T., Stack, K. M., Farley, K., and Williford, K.
- Published
- 2022
- Full Text
- View/download PDF
8. Laser-induced breakdown spectroscopy acoustic testing of the Mars 2020 microphone
- Author
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Murdoch, N., Chide, B., Lasue, J., Cadu, A., Sournac, A., Bassas-Portús, M., Jacob, X., Merrison, J., Iversen, J.J., Moretto, C., Velasco, C., Parès, L., Hynes, A., Godiver, V., Lorenz, R.D., Cais, P., Bernadi, P., Maurice, S., Wiens, R.C., and Mimoun, D.
- Published
- 2019
- Full Text
- View/download PDF
9. Impact des recommandations Afssaps 2009 sur la prise en charge de la maladie thromboembolique veineuse aux urgences : étude avant/après
- Author
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De Massari, L., Jamilloux, Y., Lega, J.-C., Sigal, A., Jacob, X., Tazarourte, K., Mensah, K., and Sève, P.
- Published
- 2018
- Full Text
- View/download PDF
10. The importance of aspirin, catheterization accuracy, and catheter design in external ventricular drainage-related hemorrhage: a multicenter study of 1002 procedures
- Author
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Woo, Peter Y. M., Ng, Ben C. F., Xiao, Jacob X., Wong, Daniel, Seto, Andrew, Lam, Sandy, Yim, Carmen, Lo, Hong-Yip, Po, Yin-Chung, Wong, Larry Y. W., Lee, Michael W. Y., Yam, Kwong-Yui, Pu, Jenny K. S., Chan, Kwong-Yau, and Poon, Wai-Sang
- Published
- 2019
- Full Text
- View/download PDF
11. The SuperCam Instrument Suite on the Mars 2020 Rover: Science Objectives and Mast-Unit Description
- Author
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Maurice, S., Wiens, R. C., Bernardi, P., Caïs, P., Robinson, S., Nelson, T., Gasnault, O., Reess, J.-M., Deleuze, M., Rull, F., Manrique, J.-A., Abbaki, S., Anderson, R. B., André, Y., Angel, S. M., Arana, G., Battault, T., Beck, P., Benzerara, K., Bernard, S., Berthias, J.-P., Beyssac, O., Bonafous, M., Bousquet, B., Boutillier, M., Cadu, A., Castro, K., Chapron, F., Chide, B., Clark, K., Clavé, E., Clegg, S., Cloutis, E., Collin, C., Cordoba, E. C., Cousin, A., Dameury, J.-C., D’Anna, W., Daydou, Y., Debus, A., Deflores, L., Dehouck, E., Delapp, D., De Los Santos, G., Donny, C., Doressoundiram, A., Dromart, G., Dubois, B., Dufour, A., Dupieux, M., Egan, M., Ervin, J., Fabre, C., Fau, A., Fischer, W., Forni, O., Fouchet, T., Frydenvang, J., Gauffre, S., Gauthier, M., Gharakanian, V., Gilard, O., Gontijo, I., Gonzalez, R., Granena, D., Grotzinger, J., Hassen-Khodja, R., Heim, M., Hello, Y., Hervet, G., Humeau, O., Jacob, X., Jacquinod, S., Johnson, J. R., Kouach, D., Lacombe, G., Lanza, N., Lapauw, L., Laserna, J., Lasue, J., Le Deit, L., Le Mouélic, S., Le Comte, E., Lee, Q.-M., Legett, IV, C., Leveille, R., Lewin, E., Leyrat, C., Lopez-Reyes, G., Lorenz, R., Lucero, B., Madariaga, J. M., Madsen, S., Madsen, M., Mangold, N., Manni, F., Mariscal, J.-F., Martinez-Frias, J., Mathieu, K., Mathon, R., McCabe, K. P., McConnochie, T., McLennan, S. M., Mekki, J., Melikechi, N., Meslin, P.-Y., Micheau, Y., Michel, Y., Michel, J. M., Mimoun, D., Misra, A., Montagnac, G., Montaron, C., Montmessin, F., Moros, J., Mousset, V., Morizet, Y., Murdoch, N., Newell, R. T., Newsom, H., Nguyen Tuong, N., Ollila, A. M., Orttner, G., Oudda, L., Pares, L., Parisot, J., Parot, Y., Pérez, R., Pheav, D., Picot, L., Pilleri, P., Pilorget, C., Pinet, P., Pont, G., Poulet, F., Quantin-Nataf, C., Quertier, B., Rambaud, D., Rapin, W., Romano, P., Roucayrol, L., Royer, C., Ruellan, M., Sandoval, B. F., Sautter, V., Schoppers, M. J., Schröder, S., Seran, H.-C., Sharma, S. K., Sobron, P., Sodki, M., Sournac, A., Sridhar, V., Standarovsky, D., Storms, S., Striebig, N., Tatat, M., Toplis, M., Torre-Fdez, I., Toulemont, N., Velasco, C., Veneranda, M., Venhaus, D., Virmontois, C., Viso, M., Willis, P., and Wong, K. W.
- Published
- 2021
- Full Text
- View/download PDF
12. Selective focusing through target identification and experimental acoustic signature extraction: Numerical experiments
- Author
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Rodriguez, S., Jacob, X., and Gibiat, V.
- Published
- 2016
- Full Text
- View/download PDF
13. Species separation of a binary mixture under acoustic streaming
- Author
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Charrier-Mojtabi, M. C., Jacob, X., Dochy, T., and Mojtabi, A.
- Published
- 2019
- Full Text
- View/download PDF
14. The sound of geological targets on Mars from the absolute intensity of laser-induced sparks shock waves
- Author
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Alvarez-Llamas, C., primary, Laserna, J., additional, Moros, J., additional, Purohit, P., additional, García-Gómez, L., additional, Angel, S.M., additional, Bernardi, P., additional, Bousquet, B., additional, Cadu, A., additional, Dauson, E., additional, Forni, O., additional, Fouchet, T., additional, Gasnault, O., additional, Jacob, X., additional, Lacombe, G., additional, Lanza, N.L., additional, Larmat, C., additional, Lasue, J., additional, Lorenz, R.D., additional, Meslin, P.-Y., additional, Mimoun, D., additional, Montmessin, F., additional, Murdoch, N., additional, Ollila, A.M., additional, Pilleri, P., additional, Randazzo, N., additional, Reyes-Newell, A.L., additional, Schröder, S., additional, Stott, A., additional, Ten Cate, J., additional, Udry, A., additional, Vogt, D., additional, Clegg, S., additional, Cousin, A., additional, Maurice, S., additional, and Wiens, R.C., additional
- Published
- 2023
- Full Text
- View/download PDF
15. Examiners' perceptions of forensic mental health assessments conducted via videoconferencing
- Author
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Skala, Josie, primary, Chavez, Jacob X., additional, Anderson, Katelin, additional, and Gulrajani, Chinmoy, additional
- Published
- 2023
- Full Text
- View/download PDF
16. Examiners' perceptions of forensic mental health assessments conducted via videoconferencing
- Author
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Josie Skala, Jacob X. Chavez, Katelin Anderson, and Chinmoy Gulrajani
- Subjects
Psychiatry and Mental health ,Clinical Psychology ,Law - Published
- 2023
- Full Text
- View/download PDF
17. Origin of a Non-Clarke’s Column Division of the Dorsal Spinocerebellar Tract and the Role of Caudal Proprioceptive Neurons in Motor Function
- Author
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Rachel Yuengert, Kei Hori, Erin E. Kibodeaux, Jacob X. McClellan, Justin E. Morales, Teng-Wei P. Huang, Jeffrey L. Neul, and Helen C. Lai
- Subjects
Biology (General) ,QH301-705.5 - Abstract
Proprioception, the sense of limb and body position, is essential for generating proper movement. Unconscious proprioceptive information travels through cerebellar-projecting neurons in the spinal cord and medulla. The progenitor domain defined by the basic-helix-loop-helix (bHLH) transcription factor, ATOH1, has been implicated in forming these cerebellar-projecting neurons; however, their precise contribution to proprioceptive tracts and motor behavior is unknown. Significantly, we demonstrate that Atoh1-lineage neurons in the spinal cord reside outside Clarke’s column (CC), a main contributor of neurons relaying hindlimb proprioception, despite giving rise to the anatomical and functional correlate of CC in the medulla, the external cuneate nucleus (ECu), which mediates forelimb proprioception. Elimination of caudal Atoh1-lineages results in mice with relatively normal locomotion but unable to perform coordinated motor tasks. Altogether, we reveal that proprioceptive nuclei in the spinal cord and medulla develop from more than one progenitor source, suggesting an avenue to uncover distinct proprioceptive functions.
- Published
- 2015
- Full Text
- View/download PDF
18. Standard for Deliberate Indifference to Inmate Safety and Medical Needs: Prison Employees Are Protected by Qualified Immunity When Making Minimal but Good-Faith Efforts to Protect Inmate Safety and Medical Needs.
- Author
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Cannoy, Ciara N., Pileggi, Brie, and Chavez, Jacob X.
- Subjects
QUALIFIED immunity of public officers ,PRISON personnel ,APATHY ,LEGAL judgments - Abstract
The article discusses two separate legal cases. In the first case, the court ruled that an inmate's waiver of counsel was intelligent, knowing, and voluntary, affirming the district court's ruling. This case highlights the tension between the right to counsel and the right to self-representation. In the second case, the court determined that prison officials were protected by qualified immunity in a deliberate indifference claim regarding inmate safety and medical needs. The court ruled that there was no constitutional right for security checks or the delivery of medical services in an emergency. The article provides a dissenting opinion and discusses the standard for deliberate indifference in correctional settings. [Extracted from the article]
- Published
- 2024
- Full Text
- View/download PDF
19. Élaboration et validation d’une fiche d’aide à la décision de limitation ou d’arrêt des traitements aux urgences
- Author
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Chirac, A., David, G., Rieg, N., Schott-Pethelaz, A.-M., Bohe, J., Carpentier, F., Jacob, X., Rhondali, W., and Filbet, M.
- Published
- 2014
- Full Text
- View/download PDF
20. Infrared light elicits endothelium-dependent vasodilation in isolated occipital arteries of the rat via soluble guanylyl cyclase-dependent mechanisms.
- Author
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Lewis, Tristan H. J., Junqi Zhuo, McClellan, Jacob X., Getsy, Paulina M., Ryan, Rita M., Jenkins, Michael. J., and Lewis, Stephen J.
- Subjects
VASODILATION ,ARTERIES ,CAROTID artery ,GUANYLATE cyclase ,BLOOD flow ,PENILE erection - Abstract
The left and right occipital arteries provide blood supply to afferent cell bodies in the ipsilateral nodose and petrosal ganglia. This supply is free of an effective blood-ganglion barrier, so changes in occipital artery blood flow directly affect the access of circulating factors to the afferent cell bodies. The application of infrared (IR) light to modulate neural and other cell processes has yielded information about basic biological processes within tissues and is gaining traction as a potential therapy for a variety of disease processes. To address whether IR can directly modulate vascular function, we performed wire myography studies to determine the actions of IR on occipital arteries isolated from male Sprague-Dawley rats. Based on our previous research that functionally-important differences exist between occipital artery segments close to their origin at the external carotid artery (ECA) and those closer to the nodose ganglion, the occipital arteries were dissected into two segments, one closer to the ECA and the other closer to the nodose ganglion. Segments were constricted with 5-hydroxytryptamine to a level equal to 50% of the maximal response generated by the application of a high (80 mM) concentration of K+ ions. The direct application of pulsed IR (1,460 nm) for 5 s produced a rapid vasodilation in occipital arteries that was significantly more pronounced in segments closest to the ECA, although the ECA itself was minimally responsive. The vasodilation remained for a substantial time (at least 120 s) after cessation of IR application. The vasodilation during and following cessation of the IR application was markedly diminished in occipital arteries denuded of the endothelium. In addition, the vasodilation elicited by IR in endothelium-intact occipital arteries was substantially reduced in the presence of a selective inhibitor of the nitric oxide-sensitive guanylate cyclase, 1H-[1,2,4] oxadiazolo [4,3-a]quinoxalin-1-one (ODQ). It appears that IR causes endotheliumdependent, nitric-oxide-mediated vasodilation in the occipital arteries of the rat. The ability of IR to generate rapid and sustained vasodilation may provide new therapeutic approaches for restoring or improving blood flow to targeted tissues. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
21. Removal of optimal cutting temperature (O.C.T.) compound from embedded tissue for MALDI imaging of lipids
- Author
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Lisa M. Butler, Xander Spotbeen, Jacob X M Truong, Jake White, Marten F. Snel, Paul J. Trim, and Johannes V. Swinnen
- Subjects
MALDI imaging ,Analyte ,010401 analytical chemistry ,Analytical chemistry ,Protonation ,02 engineering and technology ,Polyethylene glycol ,021001 nanoscience & nanotechnology ,Mass spectrometry ,01 natural sciences ,Biochemistry ,Mass spectrometry imaging ,0104 chemical sciences ,Analytical Chemistry ,Adduct ,chemistry.chemical_compound ,chemistry ,Mass spectrum ,0210 nano-technology - Abstract
Matrix-assisted laser desorption/ionisation mass spectrometry imaging (MALDI-MSI) is a common molecular imaging modality used to characterise the abundance and spatial distribution of lipids in situ. There are several technical challenges predominantly involving sample pre-treatment and preparation which have complicated the analysis of clinical tissues by MALDI-MSI. Firstly, the common embedding of samples in optimal cutting temperature (O.C.T.), which contains high concentrations of polyethylene glycol (PEG) polymers, causes analyte signal suppression during mass spectrometry (MS) by competing for available ions during ionisation. This suppressive effect has constrained the application of MALDI-MSI for the molecular mapping of clinical tissues. Secondly, the complexity of the mass spectra is obtained by the formation of multiple adduct ions. The process of analyte ion formation during MALDI can generate multiple m/z peaks from a single lipid species due to the presence of alkali salts in tissues, resulting in the suppression of protonated adduct formation and the generation of multiple near isobaric ions which produce overlapping spatial distributions. Presented is a method to simultaneously remove O.C.T. and endogenous salts. This approach was applied to lipid imaging in order to prevent analyte suppression, simplify data interpretation, and improve sensitivity by promoting lipid protonation and reducing the formation of alkali adducts.
- Published
- 2021
- Full Text
- View/download PDF
22. LIBS and Acoustic Measurements of Rocks and Regolith Found in the Traverse of the Perseverance Rover Across the Jezero Crater, Mars
- Author
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Laserna-Vázquez, José Javier, Moros, Javier, Álvarez, César, Purohit, Pablo, Ángel, S. M., Bernardi, P., Bousquet, O., Cadú, A., Chide, B., Clavé, E., Clegg, S., Dauson, E., Forni, O., Fouchet, T., Gasnault, O., Jacob, X., Lacombe, G., Lanza, N. L., Larmat, C., Lasue, J., Lorenz, R. D., Meslin, P. - Y., Montmessin, F., Murdoch, N., Ollila, A. M., Pilleri, P., Reyes-Newell, A. L., Schroder, S., Stott, A., Cate, J Ten, Vogt, D., Maurice, S., Wiens, R.C., and Mimoun, D.
- Subjects
Rocks ,Minerals ,LIBS ,Imágenes ultrasónicas ,Marte (Planeta) - Superficie ,Mars ,Rocas ,Acoustic - Abstract
The SuperCam instrument of the NASA MARS 2020 Perseverance rover combines a suite of atomic and molecular spectroscopies intended for an extensive description of rocks, soils and minerals in the surroundings of the landing site of the mission – the Jezero crater. The microphone installed on the SuperCam instrument allows the acquisition of acoustic signals resulting from the expansion of laser-induced plasmas towards the atmosphere. Apart from being affected by the propagation characteristics of the Mars atmosphere, the acoustic signal has an additional component related to the properties of the target including surface morphology, hardness, deformation parameters, and elasticity, among others. This information is currently being investigated as a complementary resource for characterization of the ablated material and may well supplement the LIBS data gathered from coincident laser shots. This talk will present SuperCam acoustic data of rocks and minerals found in the traverse of the Perseverance rover and will discuss its correlation with LIBS spectra. Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
- Published
- 2022
23. Understanding The Correlation Of Libs And Acoustic Measurements Of Rocks And Soils Found In The Traverse Of The Perseverance Rover Across The Jezero Crater, Mars
- Author
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Laserna-Vázquez, José Javier, Álvarez, C., Moros, J., Purohit, P., Ángel, S.M., Bernardi, P., Beyssac, O., Bousquet, B., Cadu, A., Chide, B., Clavé, E, Clegg, S., Dauson, E., Forni, O., Fouchet, T., Gasnault, O., Jacob, X., Lacombe, G., Lanza, N.L., Larmat, C., Lasue, J., Lorenz, R.D., Meslin, P. -Y., Montmessin, F., Murdoch, N., Ollila, A.M., Pilleri, P., Reyes-Newell, A.L., Schröder, S., Stott, A., Cate, J. Ten, Vogh, D., Maurice, S., Wiens, R.C., and Mimoun, D.
- Subjects
Rocks ,Minerals ,LIBS ,Marte (Planeta) ,Sonido ultrasónico ,Mars ,Rocas ,Acoustic - Abstract
The SuperCam instrument of the NASA MARS 2020 Perseverance rover combines a suite of atomic and molecular spectroscopies intended for an extensive description of rocks, soils and minerals in the surroundings of the landing site of the mission – the Jezero crater. The microphone installed on the SuperCam instrument allows the acquisition of acoustic signals resulting from the expansion of laser-induced plasmas towards the atmosphere. Apart from being affected by the propagation characteristics of the Mars atmosphere, the acoustic signal has an additional component related to the properties of the target including surface morphology, hardness, deformation parameters, and elasticity, among others. This information is currently being investigated as a complementary resource for characterization of the ablated material and may well supplement the LIBS data gathered from coincident laser shots. This talk will present SuperCam acoustic data of rocks and minerals found in the traverse of the Perseverance rover and will discuss its correlation with LIBS spectra. Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
- Published
- 2022
24. A rare case of Streptococcus agalactiae mycotic aneurysm and review of the literature
- Author
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Ledochowski, S., Jacob, X., and Friggeri, A.
- Published
- 2014
- Full Text
- View/download PDF
25. The Supercam Microphone to support LIBS investigation on Mars: review of the first laser-spark recordings
- Author
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Chide, B., Lanza, Nina, Alvarez, Cesar, Angel, Stanley M., Bernardi, Pernelle, Beyssac, Olivier, Bousquet, Bruno, Cadu, A., Clavé, E., Dehouck, E., Fouchet, Thierry, Gasnault, Olivier, Jacob, X., Laserna, J., Lorenz, Ralph D., Murdoch, Naomi, Stott, A. E., Maurice, Sylestre, Wiens, Roger, Mimoun, David, Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Los Alamos National Laboratory (LANL), Universidad de Málaga [Málaga] = University of Málaga [Málaga], University of South Carolina, Laboratoire d'études spatiales et d'instrumentation en astrophysique = Laboratory of Space Studies and Instrumentation in Astrophysics (LESIA), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Pôle Planétologie du LESIA, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO), Laboratoire de Géologie de Lyon - Terre, Planètes, Environnement (LGL-TPE), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut national des sciences de l'Univers (INSU - CNRS)-Université Jean Monnet - Saint-Étienne (UJM)-Centre National de la Recherche Scientifique (CNRS), Centre National d'Études Spatiales [Toulouse] (CNES), Apl, MD, USA, and Europlanet
- Subjects
[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph] - Abstract
The Mars 2020 Perseverance rover, which landed in February 2021, is carrying the SuperCam remote sensing suite [1,2]. It is a multifunctional spectroscopy instrument to analyze Martian rocks and soils with Laser-Induced Breakdown Spectroscopy (LIBS), time resolved Raman and luminescence, Visible and Infrared Reflectance Spectroscopy, and color context imaging. It also includes a microphone (see Fig. 1) that records acoustic pressure fluctuations in the 100 Hz to 10 kHz frequency bandwidth. In particular, it supports LIBS investigation by listening to laser-induced sparks caused by the supersonic expansion of the plasma plume [3, 4]. The microphone also contributes to atmospheric science by recording the ambient noise [wind, turbulence, 5, 6] and it already listened to unique sounds from the Ingenuity Mars Helicopter flights. This abstract focuses on the first analysis of the LIBS acoustic signal recorded on Martian targets near the Octavia E. Butler landing site of Perseverance. Figure 1 - WATSON image of the upper part of the Perseverance Remote Sensing Mast. The microphone is seen in the red rectangle. Credits: NASA/JPL-Caltech/MSSS/ASU Listening to laser-induced sparks on Mars: The LIBS experiment of Supercam uses a pulsed laser in the infrared (1064nm) to ablate rock or soil targets at the Mars surface at distance up to 7 meters. A standard LIBS burst consists of 30 laser shots repeated at the same location on a target. It creates an ablation pit up to hundreds of µm deep, depending on the target hardness (see LIBS pits in Fig. 2) [4, 7]. Longer bursts of 150 shots, called depth profiles, can also be performed to look for any chemical stratification with depth. Figure 2 - Hedgehog target (sol 37) sampled by LIBS (10 points of 30 shots each). (a) Mastcam-Z documentation image. (b) RMI context mosaic highlighting the LIBS pits.Credits: NASA/JPL-Caltech/ASU/MSSS and NASA/JPL-Caltech/LANL/CNES/IRAP It has been shown in lab studies [3, 4] that recording of the LIBS acoustic signal helps to determine the target physical properties (hardness) and also the laser pit volume by looking at the decrease of the signal amplitude with the number of laser shots performed at the same location. In addition, laser sparks may also be used to study rock coatings. In particular, it will help to determine the depth of the transition between a coating and its underlying host rock [8]. Moreover, as the start of the microphone recording is triggered on the laser pulse, the propagation time of the sound wave from the ground up to the microphone height is precisely measured. Therefore, it gives the sound speed along the sound propagation path. This parameter is used to estimate the ‘acoustic temperature’, an average of the air temperature over the two first meters from the ground [9]. First results on Martian targets: Up to sol 78 of the mission, the Supercam microphone has recorded the LIBS acoustic signal from 12 targets, including 3 soil targets and 2 depth profiles. The LIBS acoustic signal recorded on the float rock Hedgehog (sol 37) is represented in Fig. 3. The time series (Fig. 3a) shows a shot-to-shot decrease of the acoustic amplitude over the 30 shots fired in this target. The comparison with the hardness calibration curve presented in [4] suggests a soft target with a Vickers hardness lower than 10 and an ablated volume of about 200 µm. The frequency spectrum (Fig. 3b) is showing an acoustic bandwidth between 2 kHz and 10 kHz (see Fig. 3a), consistent with pre-flight calibrations [10]. Some gaps in the spectrum (5700 Hz, 10900 Hz, 14800 Hz) are indicative of destructive interferences induced by the reflection of the sound wave over the structure of the mast. Some wind-induced signal are also noticed in the time series (see red circles in Fig. 3a). They can be easily filtered, as their frequency content is lower than 500 Hz [6]. However, the influence of the turbulent atmosphere on the LIBS acoustic signal, needs to be assessed, as it was not tested in the laboratory. Figure 3 - Time series (a) and power spectral density (b) of the LIBS acoustic signal recorded on point #5 of the Hedgehog target (sol 37) As for the soil targets, the LIBS acoustic data show a clear decrease with increasing shot number due to shielding within the self-induced hole and also helps to determine whether the laser hit a coarse grain (louder sound) or fine-grained soil. Perspectives: The Supercam microphone has the unique capability to record the acoustic signal induced by the laser-induced plasma. The microphone will help to document the target hardness along the rover traverse and complement the chemical information provided by LIBS by adding an estimation of the ablated depth. This presentation will review results from all the microphone targets observed at the time of the conference. References [1] Wiens R. C et al., SSR 2021 https://doi.org/10.1007/s11214-020-00777-5 [2] Maurice S. et al., SSR 2021, https://doi.org/10.1007/s11214-021-00807-w [3] Chide B. et al, SAB 2019, https://doi.org/10.1016/j.sab.2019.01.008, [4] Chide B et al., SAB 2020 https://doi.org/10.1016/j.sab.2020.106000, 20, [5] Murdoch N. et al, this issue, [6] Stott et al., this issue, [7] Maurice S et al., JAAS 2016, doi:10.1039/c5ja00417a [8] Lanza N.L., LPSC 2020, 2807 [9] Chide B. et al., LPSC 2020 1366, [10] Murdoch N. 2019 PSS doi:10.1016/j.pss.2018.09.009.
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- 2021
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26. The importance of aspirin, catheterization accuracy, and catheter design in external ventricular drainage-related hemorrhage: a multicenter study of 1002 procedures
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Larry Y.W. Wong, Michael W.Y. Lee, Andrew Seto, Daniel Wong, Yin Chung Po, Wai Sang Poon, Kwong Yau Chan, Ben C.F. Ng, Sandy W. Lam, H. Y. Lo, Peter Y.M. Woo, Kwong Yui Yam, Carmen Yim, Jacob X. Xiao, and Jenny K.S. Pu
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Adult ,Male ,medicine.medical_specialty ,Catheters ,Subarachnoid hemorrhage ,Traumatic brain injury ,Neurosurgical Procedures ,Catheterization ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Hematoma ,medicine ,Humans ,Aged ,Third Ventricle ,Neuroradiology ,Intracerebral hemorrhage ,Aspirin ,medicine.diagnostic_test ,business.industry ,Interventional radiology ,Middle Aged ,medicine.disease ,Surgery ,Catheter ,Drainage ,Female ,Neurology (clinical) ,business ,Intracranial Hemorrhages ,030217 neurology & neurosurgery ,medicine.drug - Abstract
External ventricular drainage (EVD) is the commonest neurosurgical procedure performed in daily neurosurgical practice, but relatively few studies have investigated the incidence and risk factors of its related hemorrhagic complications. This was a multicenter retrospective review of consecutive EVD procedures. Patients 18 years or older who underwent EVD and had a routine postoperative computed tomography (CT) scan performed within 24 hours were included. EVD-related hemorrhage was defined as new intracranial hemorrhage immediately adjacent or within the ventricular catheter trajectory. The volume of hemorrhage and the position of the catheter tip were assessed. A review of patient-, disease-, and surgery-related factors including the ventricular catheter design utilized was conducted. The Bonferroni correction was applied to the alpha level of significance (0.05) for multivariable analysis. Nine hundred sixty-two patients underwent 1002 EVD performed by neurosurgeons in the operating theater. Sixteen percent (154) of patients were on aspirin before the procedure. Thirty-four percent (333) of patients had intracerebral hemorrhage, 25% (251) had aneurysmal subarachnoid hemorrhage and 16% (158) had traumatic brain injury. The mean duration from EVD to the first postoperative CT scan was 20 ± 4 h. EVD-related hematomas were detected after 81 procedures with a per-catheter risk of 8.1%. Mean hematoma volume was 1.2 ± 3.3 ml. Most were less than 1 ml (grade I, 79%, 64), 1 to 15 ml (grade II) in 20% (16) and a single clot larger than 15 ml (grade III, 1%) were detected. Clinically significant hemorrhage that resulted in catheter occlusion occurred in 1.7% (17) of procedures. Most catheters (62%, 625) were optimally placed, i.e., its tip being within the ipsilateral frontal horn or third ventricle. Three non-antibiotic-impregnated ventricular catheter designs were used with 55% (550) being the 2.2-mm Integra™ catheter, 14% (137) being the 2.8-mm Medtronic™ catheter, and 31% (315) being the 3.1-mm Codman™ catheter. Independent significant predictors for EVD-related hemorrhage were the preoperative prescription of aspirin (adjusted OR 1.94; 95% CI 1.10–3.44), catheter malposition (aOR 1.99; 95% CI 1.22–3.23), and use of the 2.8-mm Medtronic™ catheter (aOR 4.22; 95% CI 2.39–7.41). The per-catheter risk of hemorrhage was 8.1%, but the incidence of symptomatic hemorrhage was low. The only patient risk factor was aspirin intake. This is the first study to evaluate and establish an association between catheter malposition and catheter design with EVD-related hemorrhage.
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- 2019
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27. The SuperCam Microphone and Expected First Sounds at Jezero Crater, Mars
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Chide, Baptiste, Lanza, N. L., Alvarez, C., Angel, Stanley M., Bernardi, Pernelle, Beyssac, Olivier, Bousquet, Bruno, Cadu, A., Clavé, E., Forni, Olivier, Fouchet, Thierry, Gasnault, Olivier, Jacob, X., Lacombes, G., Laserna, J., Lasue, Jérémie, Lorenz, Ralph D., Meslin, Pierre-Yves, Montmessin, Franck, Moros, J., Murdoch, N., Ollila, Ann, Pilleri, Paolo, Puhorit, P., Reyes-Newell, A. L., Schroder, S., Stott, A., Vogt, D., Maurice, Sylestre, Wiens, Roger, Mimoun, David, Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO), Los Alamos National Laboratory (LANL), Universidad de Málaga [Málaga] = University of Málaga [Málaga], University of South Carolina [Columbia], Laboratoire d'études spatiales et d'instrumentation en astrophysique = Laboratory of Space Studies and Instrumentation in Astrophysics (LESIA), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Pôle Planétologie du LESIA, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Institut de mécanique des fluides de Toulouse (IMFT), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), Johns Hopkins University Applied Physics Laboratory [Laurel, MD] (APL), PLANETO - LATMOS, Laboratoire Atmosphères, Milieux, Observations Spatiales (LATMOS), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), DLR Institut für Planetenforschung, and Deutsches Zentrum für Luft- und Raumfahrt [Berlin] (DLR)
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[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph] - Abstract
International audience; This presentation aims to show the expected first results from the SuperCam microphone onboard the NASA Perseverance rover.
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- 2021
28. Combined LIBS and Acoustics for Differentiating Minerals with Similar LIBS Spectra
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Laserna, J., Alvarez-Llamas, C., Purohit, P., Moros, J., Luna, S., Jurado, A., Lopez, F. J., Wiens, Roger, Maurice, Sylestre, Gasnault, Olivier, Beyssac, Olivier, Lanza, Nina, Ollila, Ann, Lasue, Jérémie, Gibbons, E., Fouchet, Thierry, Lorenz, Ralph D., Mimoun, David, Delory, G., Jacob, X., Murdoch, N., Chide, B., Legett, C., Delapp, D., Pilleri, Paolo, Perez, R., Bernardi, Pernelle, Lacombe, Gaétan, Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'études spatiales et d'instrumentation en astrophysique = Laboratory of Space Studies and Instrumentation in Astrophysics (LESIA), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Pôle Planétologie du LESIA, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, and Technique
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[SDU]Sciences of the Universe [physics] ,[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph] - Abstract
International audience; The use of the plasma related spectroscopic and acoustic signals combined provide an innovative approach to characterize minerals with similar composition. This approach can help in the interpretation of the future data collected by M2020 mission.
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- 2021
29. Removal of optimal cutting temperature (O.C.T.) compound from embedded tissue for MALDI imaging of lipids
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Jacob X M, Truong, Xander, Spotbeen, Jake, White, Johannes V, Swinnen, Lisa M, Butler, Marten F, Snel, and Paul J, Trim
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Male ,Mice ,Tissue Embedding ,Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ,Prostate ,Temperature ,Animals ,Humans ,Prostatic Neoplasms ,Lipids ,Polyethylene Glycols - Abstract
Matrix-assisted laser desorption/ionisation mass spectrometry imaging (MALDI-MSI) is a common molecular imaging modality used to characterise the abundance and spatial distribution of lipids in situ. There are several technical challenges predominantly involving sample pre-treatment and preparation which have complicated the analysis of clinical tissues by MALDI-MSI. Firstly, the common embedding of samples in optimal cutting temperature (O.C.T.), which contains high concentrations of polyethylene glycol (PEG) polymers, causes analyte signal suppression during mass spectrometry (MS) by competing for available ions during ionisation. This suppressive effect has constrained the application of MALDI-MSI for the molecular mapping of clinical tissues. Secondly, the complexity of the mass spectra is obtained by the formation of multiple adduct ions. The process of analyte ion formation during MALDI can generate multiple m/z peaks from a single lipid species due to the presence of alkali salts in tissues, resulting in the suppression of protonated adduct formation and the generation of multiple near isobaric ions which produce overlapping spatial distributions. Presented is a method to simultaneously remove O.C.T. and endogenous salts. This approach was applied to lipid imaging in order to prevent analyte suppression, simplify data interpretation, and improve sensitivity by promoting lipid protonation and reducing the formation of alkali adducts.
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- 2020
30. The SuperCam Instrument Suite on the Mars 2020 Rover:Science Objectives and Mast-Unit Description
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Maurice, S., Wiens, R. C., Bernardi, P., Caïs, P., Robinson, S., Nelson, T., Gasnault, O., Reess, J. M., Deleuze, M., Rull, F., Manrique, J. A., Abbaki, S., Anderson, R. B., André, Y., Angel, S. M., Arana, G., Battault, T., Beck, P., Benzerara, K., Bernard, S., Berthias, J. P., Beyssac, O., Bonafous, M., Bousquet, B., Boutillier, M., Cadu, A., Castro, K., Chapron, F., Chide, B., Clark, K., Clavé, E., Clegg, S., Cloutis, E., Collin, C., Cordoba, E. C., Cousin, A., Dameury, J. C., D’Anna, W., Daydou, Y., Debus, A., Deflores, L., Dehouck, E., Delapp, D., De Los Santos, G., Donny, C., Doressoundiram, A., Dromart, G., Dubois, B., Dufour, A., Dupieux, M., Egan, M., Ervin, J., Fabre, C., Fau, A., Fischer, W., Forni, O., Fouchet, T., Frydenvang, J., Gauffre, S., Gauthier, M., Gharakanian, V., Gilard, O., Gontijo, I., Gonzalez, R., Granena, D., Grotzinger, J., Hassen-Khodja, R., Heim, M., Hello, Y., Hervet, G., Humeau, O., Jacob, X., Jacquinod, S., Johnson, J. R., Kouach, D., Lacombe, G., Lanza, N., Lapauw, L., Laserna, J., Lasue, J., Le Deit, L., Le Mouélic, S., Le Comte, E., Lee, Q. M., Legett, C., Leveille, R., Lewin, E., Leyrat, C., Lopez-Reyes, G., Lorenz, R., Lucero, B., Madariaga, J. M., Madsen, S., Madsen, M., Mangold, N., Manni, F., Mariscal, J. F., Martinez-Frias, J., Mathieu, K., Mathon, R., McCabe, K. P., McConnochie, T., McLennan, S. M., Mekki, J., Melikechi, N., Meslin, P.-Y., Micheau, Y., Michel, Y., Michel, J. M., Mimoun, D., Misra, A., Montagnac, G., Montaron, C., Montmessin, F., Moros, J., Mousset, V., Morizet, Y., Murdoch, N., Newell, R. T., Newsom, H., Nguyen Tuong, N., Ollila, A. M., Orttner, G., Oudda, L., Pares, L., Parisot, J., Parot, Y., Pérez, R., Pheav, D., Picot, L., Pilleri, P., Pilorget, C., Pinet, P., Pont, G., Poulet, F., Quantin-Nataf, C., Quertier, B., Rambaud, D., Rapin, W., Romano, P., Roucayrol, L., Royer, C., Ruellan, M., Sandoval, B. F., Sautter, V., Schoppers, M. J., Schröder, S., Seran, H. C., Sharma, S. K., Sobron, P., Sodki, M., Sournac, A., Sridhar, V., Standarovsky, D., Storms, S., Striebig, N., Tatat, M., Toplis, M., Torre-Fdez, I., Toulemont, N., Velasco, C., Veneranda, M., Venhaus, D., Virmontois, C., Viso, M., Willis, P., Wong, K. W., Maurice, S., Wiens, R. C., Bernardi, P., Caïs, P., Robinson, S., Nelson, T., Gasnault, O., Reess, J. M., Deleuze, M., Rull, F., Manrique, J. A., Abbaki, S., Anderson, R. B., André, Y., Angel, S. M., Arana, G., Battault, T., Beck, P., Benzerara, K., Bernard, S., Berthias, J. P., Beyssac, O., Bonafous, M., Bousquet, B., Boutillier, M., Cadu, A., Castro, K., Chapron, F., Chide, B., Clark, K., Clavé, E., Clegg, S., Cloutis, E., Collin, C., Cordoba, E. C., Cousin, A., Dameury, J. C., D’Anna, W., Daydou, Y., Debus, A., Deflores, L., Dehouck, E., Delapp, D., De Los Santos, G., Donny, C., Doressoundiram, A., Dromart, G., Dubois, B., Dufour, A., Dupieux, M., Egan, M., Ervin, J., Fabre, C., Fau, A., Fischer, W., Forni, O., Fouchet, T., Frydenvang, J., Gauffre, S., Gauthier, M., Gharakanian, V., Gilard, O., Gontijo, I., Gonzalez, R., Granena, D., Grotzinger, J., Hassen-Khodja, R., Heim, M., Hello, Y., Hervet, G., Humeau, O., Jacob, X., Jacquinod, S., Johnson, J. R., Kouach, D., Lacombe, G., Lanza, N., Lapauw, L., Laserna, J., Lasue, J., Le Deit, L., Le Mouélic, S., Le Comte, E., Lee, Q. M., Legett, C., Leveille, R., Lewin, E., Leyrat, C., Lopez-Reyes, G., Lorenz, R., Lucero, B., Madariaga, J. M., Madsen, S., Madsen, M., Mangold, N., Manni, F., Mariscal, J. F., Martinez-Frias, J., Mathieu, K., Mathon, R., McCabe, K. P., McConnochie, T., McLennan, S. M., Mekki, J., Melikechi, N., Meslin, P.-Y., Micheau, Y., Michel, Y., Michel, J. M., Mimoun, D., Misra, A., Montagnac, G., Montaron, C., Montmessin, F., Moros, J., Mousset, V., Morizet, Y., Murdoch, N., Newell, R. T., Newsom, H., Nguyen Tuong, N., Ollila, A. M., Orttner, G., Oudda, L., Pares, L., Parisot, J., Parot, Y., Pérez, R., Pheav, D., Picot, L., Pilleri, P., Pilorget, C., Pinet, P., Pont, G., Poulet, F., Quantin-Nataf, C., Quertier, B., Rambaud, D., Rapin, W., Romano, P., Roucayrol, L., Royer, C., Ruellan, M., Sandoval, B. F., Sautter, V., Schoppers, M. J., Schröder, S., Seran, H. C., Sharma, S. K., Sobron, P., Sodki, M., Sournac, A., Sridhar, V., Standarovsky, D., Storms, S., Striebig, N., Tatat, M., Toplis, M., Torre-Fdez, I., Toulemont, N., Velasco, C., Veneranda, M., Venhaus, D., Virmontois, C., Viso, M., Willis, P., and Wong, K. W.
- Abstract
On the NASA 2020 rover mission to Jezero crater, the remote determination of the texture, mineralogy and chemistry of rocks is essential to quickly and thoroughly characterize an area and to optimize the selection of samples for return to Earth. As part of the Perseverance payload, SuperCam is a suite of five techniques that provide critical and complementary observations via Laser-Induced Breakdown Spectroscopy (LIBS), Time-Resolved Raman and Luminescence (TRR/L), visible and near-infrared spectroscopy (VISIR), high-resolution color imaging (RMI), and acoustic recording (MIC). SuperCam operates at remote distances, primarily 2–7 m, while providing data at sub-mm to mm scales. We report on SuperCam’s science objectives in the context of the Mars 2020 mission goals and ways the different techniques can address these questions. The instrument is made up of three separate subsystems: the Mast Unit is designed and built in France; the Body Unit is provided by the United States; the calibration target holder is contributed by Spain, and the targets themselves by the entire science team. This publication focuses on the design, development, and tests of the Mast Unit; companion papers describe the other units. The goal of this work is to provide an understanding of the technical choices made, the constraints that were imposed, and ultimately the validated performance of the flight model as it leaves Earth, and it will serve as the foundation for Mars operations and future processing of the data.
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- 2021
31. Removal of optimal cutting temperature (O.C.T.) compound from embedded tissue for MALDI imaging of lipids
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Truong, Jacob X. M., primary, Spotbeen, Xander, additional, White, Jake, additional, Swinnen, Johannes V., additional, Butler, Lisa M., additional, Snel, Marten F., additional, and Trim, Paul J., additional
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- 2021
- Full Text
- View/download PDF
32. Authority to Determine Competence to Proceed.
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Korevec, Joseph C., McKenna, Meagan, and Chavez, Jacob X.
- Abstract
The article focuses on the case of State v. Surber, where the Nebraska Supreme Court ruled that the finder of fact holds the ultimate authority in determining competency to proceed and is responsible for weighing all evidence, regardless of expert opinions.
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- 2023
- Full Text
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33. Moisture Content Monitoring in Glulam by Electrical Methods
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Li, H., Perrin, Marianne, Eyma, Florent, Jacob, X., Gibiat, Vincent, Institut de recherches sur la catalyse et l'environnement de Lyon (IRCELYON), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Institut Clément Ader (ICA), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO), Laboratoire de Mécanique et d'Acoustique [Marseille] (LMA ), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), and Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)
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[PHYS.MECA.MEMA]Physics [physics]/Mechanics [physics]/Mechanics of materials [physics.class-ph] ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience; no abstract
- Published
- 2017
34. Reconstruction de la Carte de Vitesse d'un Milieu Inconnu par Inversion de la Forme d'Onde Complète
- Author
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Bachmann, E., Jacob, X., Komatitsch, Dimitri, Gibiat, V., Tromp, J., Laboratoire de Mécanique et d'Acoustique [Marseille] (LMA ), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Equipe Acoustique instrumentale, Sciences et Technologies de la Musique et du Son (STMS), Institut de Recherche et Coordination Acoustique/Musique (IRCAM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche et Coordination Acoustique/Musique (IRCAM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Department of Geosciences [Princeton], Princeton University, and Komatitsch, Dimitri
- Subjects
[SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph] ,[SPI.ACOU] Engineering Sciences [physics]/Acoustics [physics.class-ph] ,[SDU.STU.GP]Sciences of the Universe [physics]/Earth Sciences/Geophysics [physics.geo-ph] ,[INFO.INFO-DC] Computer Science [cs]/Distributed, Parallel, and Cluster Computing [cs.DC] ,[SDU.STU.GP] Sciences of the Universe [physics]/Earth Sciences/Geophysics [physics.geo-ph] ,[INFO.INFO-DC]Computer Science [cs]/Distributed, Parallel, and Cluster Computing [cs.DC] ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2016
35. Évaluation de la prise en charge thérapeutique de la maladie thromboembolique veineuse aux urgences : étude avant-après
- Author
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De Massari, L., primary, Gerfaud-valentin, M., additional, Mensah, K., additional, Tazarourte, K., additional, Jacob, X., additional, Jamilloux, Y., additional, Broussolle, C., additional, Sigal, A., additional, Lega, J.C., additional, and Sève, P., additional
- Published
- 2017
- Full Text
- View/download PDF
36. Origin of a Non-Clarke's Column Division of the Dorsal Spinocerebellar Tract and the Role of Caudal Proprioceptive Neurons in Motor Function
- Author
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Teng Wei P Huang, Justin E. Morales, Jeffrey L. Neul, Rachel Yuengert, Helen C. Lai, Kei Hori, Jacob X. McClellan, and Erin E. Kibodeaux
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Male ,Cerebellum ,Spinal Cord Dorsal Horn ,Movement ,Neurogenesis ,Biology ,Inbred C57BL ,Article ,General Biochemistry, Genetics and Molecular Biology ,03 medical and health sciences ,Mice ,0302 clinical medicine ,Neural Stem Cells ,medicine ,Basic Helix-Loop-Helix Transcription Factors ,Animals ,Cell Lineage ,Neurons, Afferent ,lcsh:QH301-705.5 ,Medulla ,030304 developmental biology ,Neurons ,0303 health sciences ,Medulla Oblongata ,Afferent Pathways ,Proprioception ,Dorsal spinocerebellar tract ,Anatomy ,Afferent ,Spinal cord ,Mice, Inbred C57BL ,medicine.anatomical_structure ,lcsh:Biology (General) ,Medulla oblongata ,Female ,Biochemistry and Cell Biology ,Forelimb ,030217 neurology & neurosurgery - Abstract
© 2015 The Authors. Proprioception, the sense of limb and body position, is essential for generating proper movement. Unconscious proprioceptive information travels through cerebellar-projecting neurons in the spinal cord and medulla. The progenitor domain defined by the basic-helix-loop-helix (bHLH) transcription factor, ATOH1, has been implicated in forming these cerebellar-projecting neurons; however, their precise contribution to proprioceptive tracts and motor behavior is unknown. Significantly, we demonstrate that Atoh1-lineage neurons in the spinal cord reside outside Clarke's column (CC), a main contributor of neurons relaying hindlimb proprioception, despite giving rise to the anatomical and functional correlate of CC in the medulla, the external cuneate nucleus (ECu), which mediates forelimb proprioception. Elimination of caudal Atoh1-lineages results in mice with relatively normal locomotion but unable to perform coordinated motor tasks. Altogether, we reveal that proprioceptive nuclei in the spinal cord and medulla develop from more than one progenitor source, suggesting an avenue to uncover distinct proprioceptive functions.
- Published
- 2015
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- View/download PDF
37. Alcohol Consumption for People Admitted in French Emergency Departments: A Protocol for a Multi-Center Cluster Trial
- Author
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Chalmeton M, Viallon A, Georges Brousse, Maurice Dematteis, Guelon T, Lesage P, Farès Moustafa, Pierre-Michel Llorca, Genty A, J. Geneste, Delphine Ragonnet, Françoise Carpentier, Laurent Malet, Jacob X, De Chazeron I, CHU Clermont-Ferrand, Service d'accueil des urgences médicales, CHU Grenoble, Département des Urgences, Kereden, Hypoxie : Physiopathologie Respiratoire et Cardiovasculaire (HP2), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Neuro-Psycho Pharmacologie des Systèmes Dopimanégiques sous-corticaux (NPsy-Sydo), CHU Clermont-Ferrand-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), and Ingrid, de Chazeron
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medicine.medical_specialty ,Pediatrics ,Epidemiology ,[SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health ,Population ,Disease cluster ,03 medical and health sciences ,0302 clinical medicine ,Self-questionnaire ,Environmental health ,Medicine ,030212 general & internal medicine ,education ,Substance misuse ,Accident and emergency medicine ,France Lander ,education.field_of_study ,Alcohol Use Disorders Identification Test ,business.industry ,Public health ,Alcohol dependence ,Emergency department ,3. Good health ,[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie ,[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health ,Observational study ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,Public Health ,business ,Developed country ,030217 neurology & neurosurgery - Abstract
International audience; Background: According to a 2014 report by the World Health Organization, the highest alcohol consumption levels per capita continue to be found in the developed world, particularly in the European region. Drinking alcohol does not only lead to alcohol dependence; it also be linked to a higher risk for acute medical and surgical events. In France, recent data show that alcohol consumption levels in the general population are important and have remained relatively stable since 2010. In the Emergency Department population, few French data are available, while studies conducted across the Atlantic show that patients admitted into emergency rooms are reported to have high levels of alcohol consumption. Emergency Departments are an important location for the identification and early intervention of issues related to alcohol consumption. Therefore, the aim of this study is to carry out an epidemiological picture of alcohol consumption and search for indicators of harmful alcohol use in patients in the French emergency rooms of the Rhône-Alpes-Auvergne interregion. Methods and Analysis: This observational, and descriptive and randomized clinical study on human beings will consists of a collection of clinical variables on all patients that will be admitted to the Emergency Departments of the RAA Rhône-Alpes-Auvergne interregion aged of (16 years or older) and who will be agree to participate to the study. It will include one visit where the patient will respond to three auto-administrating screening tests on his or her alcohol consumption: Alcohol Use Disorders Identification Test – C (AUDIT C), Cut-down, Annoyed, Guilty, Eye-opener test (CAGE) and the Rapid Alcohol Problems Screen – Quantity Frequency test (RAPS4 – QF). Similarly, they will answer two self-administering questionnaires on socio-demographic and emergency data.
- Published
- 2015
- Full Text
- View/download PDF
38. Elastic-wave transmission through self-similar anisotropic Cantor-like multilayers
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Ponge, M.-F., primary, Jacob, X., additional, and Gibiat, V., additional
- Published
- 2016
- Full Text
- View/download PDF
39. Monitoring of the curing process of an industrial composite structure by TJS and FUT
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Torres, M., Collombet, Francis, Douchin, Bernard, Crouzeix, Laurent, Bazer-Bachi, R., Grunevald, Y.-H., Lubin, J., Camps, T., Jacob, X., Rodriguez, S., Wu, K.-T., Institut Clément Ader (ICA), Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), and Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO)
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[PHYS.MECA.MSMECA]Physics [physics]/Mechanics [physics]/Materials and structures in mechanics [physics.class-ph] - Abstract
International audience; In this work, a multi-instrumentation setup is conceived in order to have a better understanding of composites curing by using different devices: tunnelling junction sensor (TJS), flexible ultrasonic transducers (FUT) and thermocouples. The sensors are simultaneously embedded or placed on the surface of a thick carbon-epoxy plate for monitoring its autoclave cycle. By means of their signals, the evolution of temperature related with the polymerization state is described. A qualitative statement is provided to have a first approach of the initial state of the composite plate in order to improve its mechanical properties.
- Published
- 2013
40. Des avancées dans le suivi de cuisson des pièces composites
- Author
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Collombet, Francis, Luyckx, G., Sonnenfeld, C., Grunevald, Y.-H., Davila, Yves, Torres, M., Jacob, X., Wu, K.-T., Douchin, Bernard, Crouzeix, Laurent, Bazer-Bachi, R., Geernaert, T., Degrieck, J., Berghmans, F., Institut Clément Ader (ICA), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO), Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), and Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)
- Subjects
[PHYS.MECA.MSMECA]Physics [physics]/Mechanics [physics]/Materials and structures in mechanics [physics.class-ph] - Abstract
International audience; Ce papier présente une partie des résultats obtenus dans le cadre du projet appelé "Instrumentation Multi-capteur des Matériaux et structures composites (I2MC)" soutenu par la fondation RTRA STAE de Toulouse. L’objectif principal du papier est de montrer la complémentarité de différents capteurs comme les capteurs ultrasons flexibles (FUT) et les fibres optiques micro-structurées (MOF) et DTG®, afin d’identifier l'état initial de la structure composite par la mesure des déformations résiduelles. Avec les FUTs, si aucune déformation ne peut être évaluée, l’instant où le transfert entre le matériau composite et la fibre optique est effectif est établi. On peut déterminer le début du temps de gel et les déformations résiduelles transversales correspondantes mesurées par les fibres optiques à réseaux de Bragg (FORBGs) de type MOF. Couplées avec les mesures des FORBGs de type DTGS®, incorporées dans des capillaires pour éviter l'influence des déformations résiduelles transversales, on obtient une information d'ensemble complète des déformations résiduelles induites.
- Published
- 2013
41. Law School Applicants Disability Discrimination Claim Rejected.
- Author
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Baz, Asli and ChÃvez, Jacob X.
- Subjects
DISCRIMINATION against people with disabilities ,DISABILITY laws ,LAW schools ,EDUCATIONAL law & legislation ,PSYCHOTHERAPY ,AMERICANS with Disabilities Act of 1990 - Published
- 2021
- Full Text
- View/download PDF
42. Exploiting the temperature insensitivity of the modal birefringence of micro-structured fibre Bragg gratings for cure cycle monitoring
- Author
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Collombet, Francis, Luyckx, G., Sonnenfeld, C., Grunevald, Y.-H., Lammens, N., DAVILA, Yves, Torres, M., Jacob, X., Wu, K.-T., Douchin, Bernard, Crouzeix, Laurent, Bazer-Bachi, R., Geernaert, T., Degrieck, J., Berghmans, F., Institut Clément Ader (ICA), Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), and Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO)
- Subjects
[PHYS.MECA.MSMECA]Physics [physics]/Mechanics [physics]/Materials and structures in mechanics [physics.class-ph] ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience; no abstract
- Published
- 2012
43. Assessing the incidence rates of substance use disorders among those with antisocial and borderline personality disorders in rural settings
- Author
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Chávez, Jacob X, Dinsmore, Julie A, and Hof, David D.
- Subjects
Asmenybės sutrikimai ,Narkomanai ,Personality disorders ,Drug addicts - Abstract
Dauguma tyrimų, kuriuose nagrinėjamos asocialaus tipo asmenybės sutrikimo (ATAS), ribinio tipo asmenybės sutrikimo (RTAS) ir probleminio narkotinių medžiagų vartojimo sąsajos, didžiausią dėmesį kreipia į tai, kokios medžiagos vartojamos (Chapman, Cellucci, 2007; Skodol, Oldham, Gallaher, 1999; Trull, Waudby, Sher, 2004; Sher, Trull, 2002), arba siekia atskleisti elgesį, kuris numato narkotinių medžiagų vartojimą. Tačiau tik keliuose tyrimuose plačiau buvo nagrinėjamas piktnaudžiavimas kanapėmis ir amfetaminu (Skodol et al. 1999; Regier, et al. 1990), įtraukiami psichiatrijos stacionaruose besigydantys asmenys (Trull, et al. 2004; Rounsaville, et al., 1998), ar susitelkiama į kaimo vietovę. Tyrimo tikslas. Atskleisti asocialaus ir ribinio tipo asmenų, gyvenančių kaimo vietovėse, asmenybės sutrikimų sąsajas su probleminiu narkotinių medžiagų vartojimu, įskaitant ir kanapių produktus bei amfetaminą. Metodika. Tyrime analizuojami vieno JAV kaimo bendruomenės psichiatrinių paslaugų stacionaro archyviniai duomenys apie asmenybės sutrikimų diagnozes ir probleminio narkotinių medžiagų vartojimą. Rezultatai. Asmenų, kuriems buvo diagnozuotas ATAS, grupėje probleminio narkotinių medžiagų vartojimo paplitimas buvo reikšmingai didesnis, nei RTAS asmenų grupėje. ATAS asmenų grupėje piktnaudžiauta kanapėmis dvigubai daugiau (54,76 %), palyginti su RTAS grupe (19,77 %). Maždaug trečdalis ATAS grupės asmenų piktnaudžiavo amfetaminu (30,95 %), RTAS grupėje tokių asmenų buvo 13,56 %... [toliau žr. visą tekstą] Studies regarding the correlation between Antisocial Personality Disorder (ASPD) and Borderline Personality Disorder (BPD) diagnoses and Substance Use Disorders (SUDs) have focused on substances used (Chapman, Cellucci, 2007; Skodol, Oldham, Gallaher, 1999; Trull, Waudby, Sher, 2004; Sher, Trull, 2002), or behaviors that predict a SUD. Few studies have addressed the rates of cannabis and amphetamine abuse (Skodol, et al. 1999; Regier, et al. 1990), involved inpatient psychiatric populations (Trull, et al. 2004; Rounsaville, et al., 1998), or focused on rural populations. Purpose. This study compares ASPD and BPD diagnoses and abuse rates, including amphetamine and cannabis use, in a rural setting. Methods and Results. Archival data on diagnosis and abuse rates were compared for patients in an R an inpatient psychiatric facility in a rural community in the United States diagnosed with BPD or ASPD. Use rates were significantly higher for the ASPD group than the BPD group for all substances, with over half with ASPD (54.76 %) abusing cannabis compared with about 20 % (19.77 %) of those with BPD. Almost one third (30.95 %) with ASPD abused amphetamines compared to 13.56 % of those with BPD. The incidence of alcohol use in the ASPD group was three times higher than in previous studies on non-rural populations. Conclusions. Practitioners in rural settings should assess for both cannabis and amphetamine use as they often accompany alcohol use. A psycho-educational focus on... [to full text]
- Published
- 2010
44. Elasticity profile of an unconsolidated granular medium inferred from guided waves: Toward acoustic monitoring of analogue models
- Author
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Bodet, L., Jacob, X., Tournat, V., Mourgues, R., and Gusev, V.
- Published
- 2010
- Full Text
- View/download PDF
45. De l’intérêt des hémocultures dans les pyélonéphrites aux urgences
- Author
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Ledochowski, S., primary, Abraham, P., additional, Jacob, X., additional, Lepape, A., additional, Wallet, F., additional, and Friggeri, A., additional
- Published
- 2014
- Full Text
- View/download PDF
46. Pliocene warmth, polar amplification and stepped Pleistocene cooling recorded in NE Arctic Russia
- Author
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Brigham-Grette, Julie, Melles, M., Minyuk, P., Andreev, Andreev, Tarasov, P. E., DeConto, R., DeConto, S., Nowaczyk, Norbert R., Wennrich, V, Rosén, P, Haltia, E, Cook, T., Gebhardt, Catalina, Meyer-Jacob, X, Snyder, Jeff, Herzschuh, Ulrike, Brigham-Grette, Julie, Melles, M., Minyuk, P., Andreev, Andreev, Tarasov, P. E., DeConto, R., DeConto, S., Nowaczyk, Norbert R., Wennrich, V, Rosén, P, Haltia, E, Cook, T., Gebhardt, Catalina, Meyer-Jacob, X, Snyder, Jeff, and Herzschuh, Ulrike
- Published
- 2013
47. Prévalence des urgences cardiovasculaires dans le réseau Rescue : deux types d’enquêtes apportent des résultats concordants et complémentaires
- Author
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Douheret, F., primary, Jacob, X., additional, Eydoux, N., additional, Champagnac, D., additional, Lablanche, C., additional, and El houry, C., additional
- Published
- 2009
- Full Text
- View/download PDF
48. Surface-wave dispersion inversion in an unconsolidated granular medium
- Author
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Bodet, L., primary, Jacob, X., additional, Tournat, V., additional, Mourgues, R., additional, and Gusev, V., additional
- Published
- 2009
- Full Text
- View/download PDF
49. Acoustic Probing of the Jamming Transition in an Unconsolidated Granular Medium
- Author
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Jacob, X., primary, Aleshin, V., additional, Tournat, V., additional, Leclaire, P., additional, Lauriks, W., additional, and Gusev, V. E., additional
- Published
- 2008
- Full Text
- View/download PDF
50. Mise en place d'un réseau médecine d'urgence–cardiologie de ville pour la prise en charge des syndromes coronaires aigus à bas risque
- Author
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El Khoury, C., primary, Jacob, X., additional, Matas, O., additional, and Jules, J.-M., additional
- Published
- 2007
- Full Text
- View/download PDF
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