1. Risk Factors for Mortality and Circulatory Outcome Among Neonates Prenatally Diagnosed With Ebstein Anomaly or Tricuspid Valve Dysplasia: A Multicenter Study
- Author
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Freud, Lindsay R, McElhinney, Doff B, Kalish, Brian T, Escobar‐Diaz, Maria C, Komarlu, Rukmini, Puchalski, Michael D, Jaeggi, Edgar T, Szwast, Anita L, Freire, Grace, Levasseur, Stéphanie M, Kavanaugh‐McHugh, Ann, Michelfelder, Erik C, Moon‐Grady, Anita J, Donofrio, Mary T, Howley, Lisa W, Tierney, Elif Seda Selamet, Cuneo, Bettina F, Morris, Shaine A, Pruetz, Jay D, van der Velde, Mary E, Kovalchin, John P, Ikemba, Catherine M, Vernon, Margaret M, Samai, Cyrus, Satou, Gary M, Gotteiner, Nina L, Phoon, Colin K, Silverman, Norman H, and Tworetzky, Wayne
- Subjects
Pediatric ,Perinatal Period - Conditions Originating in Perinatal Period ,Lung ,Cardiovascular ,Heart Disease ,Infant Mortality ,Clinical Research ,Good Health and Well Being ,Blood Flow Velocity ,Ebstein Anomaly ,Echocardiography ,Female ,Heart Valve Diseases ,Hospital Mortality ,Humans ,Infant ,Newborn ,Logistic Models ,Male ,Perinatal Mortality ,Prenatal Diagnosis ,Retrospective Studies ,Risk Factors ,Tricuspid Valve ,congenital heart disease ,Ebstein anomaly ,mortality ,neonate ,outcome ,palliation ,right ventricle ,tricuspid regurgitation ,Cardiorespiratory Medicine and Haematology - Abstract
Background In a recent multicenter study of perinatal outcome in fetuses with Ebstein anomaly or tricuspid valve dysplasia, we found that one third of live-born patients died before hospital discharge. We sought to further describe postnatal management strategies and to define risk factors for neonatal mortality and circulatory outcome at discharge. Methods and Results This 23-center, retrospective study from 2005 to 2011 included 243 fetuses with Ebstein anomaly or tricuspid valve dysplasia. Among live-born patients, clinical and echocardiographic factors were evaluated for association with neonatal mortality and palliated versus biventricular circulation at discharge. Of 176 live-born patients, 7 received comfort care, 11 died
- Published
- 2020