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In this article, we have reported the synthesis and structural characterization of complexes containing Co(III), Cu(II), Zn(II), and Hg(II) metal cations. The ligand potassium azepane-1-carbodithioate (acdt) behaves as a monodentate and bidentate and forms complexes with the metals mentioned above. We investigated the electronic and emission spectra of the ligand potassium azepane-1-carbodithioate (acdt) and its metal complexes [Co(acdt)3]·CHCl3 (1), [Cu(acdt)2] (2), [Zn2(μ2-acdt)2(acdt)2] (3), and [PhHg(acdt)] (4). A photoluminescence study was also carried out and the results revealed that all compounds are fluorescent. Furthermore, this synthesized ligand and its complexes are passed through to examine their cytotoxic activity against human breast cancer cell line MDA-MB-231 and results suggested that complex [Co(acdt)3]·CHCl3 has sufficiently better activity than others. Furthermore, we have explored the impact of the synthesized ligand and its transition metal complexes on glucose metabolism within the human breast cancer cell line MDA-MB-231. Inhibiting glucose uptake can induce starvation in cancer cells, potentially resulting in cell death due to energy deprivation. Our results indicate that the Co(III) complex-treated group exhibited a greater inhibition of glucose uptake compared to groups treated with ligands and other metal complexes such as Cu, Zn, and Hg. Furthermore, we also measured the extracellular NO level in the ligand and its metal complexes of Co(III), Cu(II), Zn(II), and Hg(II) treated MDA-MB-231 cells and results indicated that the free ligand and its metal complexes induced the production of nitric oxide in MDA-MB-231 cells. Among the four metal complexes, Co-complex 1 elevated the nitric oxide level in MDA-MB-231 cells to 75.91 μM. In contrast, the groups treated with the complexes of Cu(II) (2), Zn(III) (3), and Hg(II) (4) induced NO levels of 62.91, 49.24, and 33.10 μM, respectively. This suggests that complex 1 induces nitric oxide production and enhances oxidative stress in MDA-MB-231 cells more significantly compared to the groups treated with the free ligand as well as with metal complexes 2–4. Overall, the data strongly suggest that complex 1 exhibits significant anticancer activity against the human breast cancer cell line MDA-MB-231, making it a promising candidate for combating breast cancer progression. [ABSTRACT FROM AUTHOR]

This study conducts a literature review to analyse the incorporation of Industry 4.0 in the construction sector, known as Construction 4.0, in developing countries. This study utilises an effective technique, encompassing academic databases, journals, and conference proceedings, to carefully examine relevant studies published with respect to developing countries. The primary areas of emphasis involve the definition of Construction 4.0. The technologies of execution include six cutting-edge technologies such as Building Information Modelling (BIM), Internet of Things (IoT), robotics, 3D printing, UAVs, and artificial intelligence in construction procedures. This analysis also explores the awareness and understanding of Industry 4.0 in the construction sector (Construction 4.0) in developing countries before identifying where it is being applied therein. Furthermore, obstacles that impede the mainstream adoption in developing countries are identified, including but not limited to such things as insufficient technological infrastructure, skill deficiencies, and budgetary limitations. This review consolidates various studies to provide a thorough comprehension of the present condition of Construction 4.0 in developing nations. As such, this paper aims to provide a guide for future research, policy making, and industry practices in order to promote sustainable and technologically advanced construction methods in these settings. [ABSTRACT FROM AUTHOR]

Poa sachensis, a new species from the Sach Pass, Western Himalaya, is described and illustrated. It is a member of P. subg. Ochlopoa sect. Alpinae, and closely allied to P. alpina, but differs from the latter by its lower glume one‐nerved, callus scantly hairy, lemma (3.87–) 4.18–4.54 (–4.65) mm long, purplish, surface between nerves glabrous, palea proliferate and keels ciliate 1/2nd to 1/3rd part, and two stamens in fertile floret with anther (2.42–) 2.67–3.08 (–3.21) mm long. Further, we have added P. diaphora var. alpina for the first time to the flora of India based on specimens collected from the semiarid habitats of Spiti Valley. Information on the distribution, habitat, flowering, and fruiting cycles is provided along with a distribution map for each taxon. Keywords: alpine grasses, Poa alpina, P. subg. Pseudopoa, P. subg. Ochlopoa, Western Himalaya [ABSTRACT FROM AUTHOR]