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Lipoprotein(a) [Lp(a)] contributes to cardiovascular disease risk. A genetically determined size polymorphism in apolipoprotein(a) [apo(a)], determined by the number of Kringle (K) repeats, inversely regulates Lp(a) levels. Nongenetic factors including dietary saturated fat influence Lp(a) levels. However, less is known about the effects of carbohydrates including dietary sugars. In this double-blind, parallel arm study among 32 overweight/obese adults, we investigated the effect of consuming glucose- or fructose-sweetened beverages providing 25% of energy requirements for 10 weeks on Lp(a) level and assessed the role of the apo(a) size polymorphism. The mean (±SD) age of participants was 54 ± 8 years, 50% were women, and 75% were of European descent. Following the 10-week intervention, Lp(a) level was reduced by an average (±SEM) of -13.2% ± 4.3% in all participants (P = 0.005); -15.3% ± 7.8% in the 15 participants who consumed glucose (P = 0.07); and -11.3% ± 4.5% in the 17 participants who consumed fructose (P = 0.02), without any significant difference in the effect between the two sugar groups. Relative changes in Lp(a) levels were similar across subgroups of lower versus higher baseline Lp(a) level or carrier versus noncarrier of an atherogenic small (≤22K) apo(a) size. In contrast, LDL-C increased. In conclusion, in older, overweight/obese adults, consuming sugar-sweetened beverages reduced Lp(a) levels by ∼13% independently of apo(a) size variability and the type of sugar consumed. The Lp(a) response was opposite to that of LDL-C and triglyceride concentrations. These findings suggest that metabolic pathways might impact Lp(a) levels.

In this work, the Marangoni convective flow of magnetohydrodynamic tangent hyperbolic (Fe3O4−Cu/{{\rm{F}}{{\rm{e}}}_{3}{\rm{O}}}_{4}-{\rm{Cu}}/ethylene glycol) hybrid nanofluids over a plate dipped in a permeable material with heat absorption/generation, heat radiation, elastic deformation and viscous dissipation is discussed. The impact of activation energy is also examined. Hybrid nanofluids are regarded as advanced nanofluids due to the thermal characteristics and emerging advantages that support the desire to augment the rate of heat transmission. The generalized Cattaneo–Christov theory, which takes into account the significance of relaxation times, is modified for the phenomena of mass and heat transfer. The fundamental governing partial differential equations are converted to ordinary differential equations (ODEs) by adopting similarity variables. The Runge–Kutta–Fehlberg-45 technique is utilized to solve nonlinear ODEs. Regarding the non-dimensional embedded parameters, a graphic investigation of the thermal field, concentration distribution, and velocity profile is performed. The results show that the increasing Marangoni ratio parameter enhances velocity and concentration distributions while decreases the temperature distribution. The velocity profile is decreased and the efficiency of heat transfer is improved as the porosity parameter is increased. Nusselt number is diminished with the rising values of the porosity variable.

This research endeavors to conduct an examination of the thermal characteristics within the duct filled with the copper nanoparticles and water as base fluid. In exhaust systems, like car exhausts, chimneys, and kitchen hoods, duct flows are crucial. These systems safely discharge odors, smoke, and contaminants into the atmosphere after removing them from enclosed places. The study focuses on a laminar flow regime that is both hydrodynamically and thermally developed, with a specified constraints at any cross-sectional plane. To address this, we employ the finite volume method as it stands as a judicious choice, offering a balance between computational efficiency and solution accuracy. Notably, we have observed that the deceleration of flow induced by elevated Rayleigh numbers can be effectively regulated by the application of an appropriately calibrated external magnetic field. The prime parameters of the problem with ranges are: pressure gradient (1≤p0≤100)(1\le {p}_{0}\le 100), Hartmann number (0≤Ha≤50)(0\le \text{Ha}\le 50), Rayleigh number (1,000≤Ra≤40,000)(1,000\le \text{Ra}\le 40,000), and magnetic parameter (0≤M≤50)(0\le M\le 50). Furthermore, our analysis reveals that the Nusselt number exhibits a nearly linear correlation with the nanoparticle volume fraction parameter, a trend observed across a range of Rayleigh numbers and magnetic parameter values. We have noted that a mere 20% nanoparticle volume fraction can result in up to 62% rise in the Nusselt number while causing an almost 50% decrease in the factor f Re. This research framework serves as a robust foundation for understanding the intricate interplay between magnetic influences and thermal-hydraulic behavior within the delineated system.

Abstract The detection and characterisation of electromagnetic signals within a specific frequency range, known as spectrum sensing, plays a crucial role in Cognitive Radio Networks (CRNs). The CRNs aim to adapt their communication parameters to the surrounding radio environment, thereby improving the efficiency and utilisation of the available radio spectrum. Spectrum sensing is particularly important in device‐to‐device (D2D) communication when operating independently of the cellular network infrastructure. The Medium Access Control (MAC) protocol coordinates device communication and ensures interference‐free operation of the CRN coexisting with the primary cellular network. A spectrum sensing strategy at the MAC layer for cognitive D2D communication. The strategy focuses on reducing the overall sensing period allocated at the MAC layer by having each Cognitive D2D User (cD2DU) sense a smaller subset of available channels while maintaining the same sensing time for cellular user detection at the physical layer. To achieve this, the concept of concurrent groups of D2D devices is introduced in proximity, which are formed by using unique IDs of cD2DUs during the device discovery stage. Each concurrent group senses a specific portion of the cellular user band in a shorter time, resulting in a reduced overall sensing period. In addition to mitigating traffic congestion through data diversion from the cellular network, the proposed strategy facilitates the concurrent sensing of multiple channels by cD2DUs within the underutilised cellular user band. This leads to extended data transmission periods, increased network throughput, and effective offloading of the cellular network. The effectiveness of the proposed work is evaluated by considering factors, such as network throughput and transmission time. Simulation results confirm the effectiveness of the approach in improving spectrum utilisation and communication efficiency in multi‐channel Cognitive D2D Networks (cD2DNs).

Abstract Solar cells are increasingly being utilised for both energy harvesting and reception in free‐space optical (FSO) communication networks. The authors focus on the implementation of a mid‐band p‐In0.01Ga0.99 N/p‐In0.5Ga0.5 N/n‐In0.5Ga0.5 N (PPN) solar cell, boasting an impressive 26.36% conversion efficiency (under 1.5AM conditions) as a receiver within an indoor FSO communication network. Employing a solar cell with dimensions of 1 mm in length and width, the FSO system underwent simulation using Optisystm software, while the solar cell's behaviour was simulated using SCAPS‐1D. The received power from the solar cell was then compared to that of four commercially available avalanche photodiode (APD) receivers. Exploring incident wavelengths spanning 400–700 nm within the visible spectrum, across transmission distances of 5, 10, 15, and 20 m, the study presented current‐voltage (IV) and power‐voltage curves. Notably, the InGaN solar cell exhibited superior electrical power output compared to all commercial APDs. In conclusion, the findings underscore that augmenting received power has the potential to enhance FSO network quality and support extended transmission distances.

Abstract Heterogeneous networks (HetNets) refer to the communication network, consisting of different types of nodes connected through communication networks deploying diverse radio access technologies like LTE, Wi‐Fi, Zigbee, and Z‐wave, and using different communication protocols and operating frequencies. Vertical handover, is the process of switching a mobile device from one network type to another, such as from a cellular network to a Wi‐Fi network, and is critical for ensuring a seamless user experience and optimal network performance, within the handover process handover triggering estimation is one of the crucial step affecting the overall performance. A mathematical analysis is presented for the handover triggering estimation. The performance evaluation shows significant improvement in the probability of successful handover using the proposed handover triggering condition based on speed, distance, and different mobility models. The handover triggering condition is optimised based on the speed of the mobile node, handover completion time, and the coverage range of the current and the target networks of the HetNet node, with due consideration of the mobility model.

Introduction: Full outline of unresponsiveness (FOUR) score has advantages over Glasgow Coma Scale (GCS); as it can be used in intubated patients and provides greater neurological details. It has been studied mainly in the trauma and neuroscience setting. Our primary objective was to compare the FOUR versus GCS score as predictors of mortality at 30 days and poor functional outcome at 3 months among nontrauma patients in the emergency department (ED). Methods: This prospective observational study was conducted on adult patients presenting with altered mental status (duration

The purpose of the current research is to inspect the free convection of the nanofluid (Cu–water) within a hexagonal cavity containing a square obstacle with isothermal vertical walls at Th{T}_{{\rm{h}}} and Tc{T}_{{\rm{c}}}, and insulated horizontal walls. The aim of this study is to analyze the interaction between the Rayleigh number (103

Ternary hybrid nanofluids possess improved thermal characteristics, enhanced stability, better physical strength, and multi-functionality as compared to hybrid or usual nanofluids. The aim of the ongoing study is to explore the novel thermal attributes of hybrid and trihybrid nanofluids through a porous medium. Whereas the nano-composition of cobalt (Co), gold (Au), and zirconium oxide (ZrO2) make amalgamation in the paraffin (Pfin) which is a base fluid. This nano-composition of the proposed nanoparticles, specifically, subject to the base fluid Pfin has not been interpreted before. The analysis not only covers the features of trihybrid nanofluids (Co–Au–ZrO2–Pfin) but it also describes the characteristics of hybrid (Co–Au–Pfin) as well as pure nanofluids (Co–Pfin). An efficient numerical algorithm is developed for which the numerical simulations are carried out. The approximations are performed in MATLAB software using “Successive under Relaxation (SUR)” technique. A comparison, under certain limiting conditions, with the established results appraises the efficiency of the numerical code. The outcomes evidently designate that temperature raises with the change in thermal radiation and volume fraction of gold and zirconium oxide in either case of pure, hybrid, or ternary nanofluids. The concentration ϕ3{\phi }_{3} of ZrO2 has a significant impact on Nusselt number rather than the concentration ϕ1{\phi }_{1} of cobalt and ϕ2{\phi }_{2} of gold. It has been comparatively noticed that the ternary nanofluids (Co–Au–ZrO2–Pfin) portray embellished and improvised thermal characteristics as compared to the other two cases.