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23 results on '"Janssen, Wilbert M.T."'

1. Discontinuation of Antihypertensive Medications on the Outcome of Hospitalized Patients With Severe Acute Respiratory Syndrome-Coronavirus 2

Author

Singh, Sandeep, primary, Offringa-Hup, Annette K., additional, Logtenberg, Susan J.J., additional, Van der Linden, Paul D., additional, Janssen, Wilbert M.T., additional, Klein, Hubertina, additional, Waanders, Femke, additional, Simsek, Suat, additional, de Jager, Cornelis P.C., additional, Smits, Paul, additional, van der Feltz, Machteld, additional, Jan Beumer, Gerrit, additional, Widrich, Christine, additional, Nap, Martijn, additional, and Pinto-Sietsma, Sara-Joan, additional

Published
2021
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2. Effects of Short-Term Potassium Chloride Supplementation in Patients with CKD

Author

Gritter, Martin, Wouda, Rosa D., Yeung, Stanley M.H., Wie?rs, Michiel L.A., Geurts, Frank, de Ridder, Maria A.J., Ramakers, Christian R.B., Vogt, Liffert, de Borst, Martin H., Rotmans, Joris I., Hoorn, Ewout J., Boom, Henk, de Graaf Gasthuis, Reinier, Gabre?ls, Bas Ah.T.F., Groeneveld, Marc, Janssen, Wilbert M.T., Korte, Mario R., Laverman, Goos D., van der Lubbe, Nils, van der Net, Jeroen B., Soonawala, Darius, Swart, Reinout M., and Verhoeven, Martine A.M.

Abstract

Observational studies show health benefits from a higher potassium intake, but it is unknown if this is tolerated by patients with CKD. This 2-week study indicates that 40 mmol/day potassium chloride supplementation (the estimated gap between actual and adequate intake) increased plasma potassium by 0.4 mmol/L in 191 patients with CKD (eGFR 31 ml/min per 1.73 m2, 83% on renin-angiotensin inhibitors). The majority of patients (89%) remained normokalemic. Higher baseline plasma potassium and older age were risk factors for developing hyperkalemia after supplementation. Potassium chloride supplementation did not lower office BP, but did cause a tendency toward hyperchloremic metabolic acidosis. Longer-term studies should determine whether the cardiorenal benefits of adequate dietary potassium intake outweigh the risk of hyperkalemia in patients with CKD.

Published
2022
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10. Inadequate management of blood pressure in a hypertensive population

Author

Sechi, Leonardo A., Zingaro, Laura, Bartoli, Ettore, Ward, Harry J., Pinto-Sietsma, Sara-Joan, Hillege, Hans L., Janssen, Wilbert M.T., Berlowitz, Dan R., Ash, Arlene S., and Moskowitz, Mark A.

Subjects
Hypertension -- Care and treatment, Aged men -- Care and treatment
Published
1999

11. Rationale, design, and baseline characteristics of a trial of prevention of cardiovascular and renal disease with fosinopril and pravastatin in nonhypertensive, nonhypercholesterolemic subjects with microalbuminuria (the prevention of REnal and vascular ENdstage disease intervention trial [PREVEND IT])

Author

Diercks, Gilles F.H., Janssen, Wilbert M.T., van Boven, Ad J., Bak, Annette A.A., de Jong, Paul E., Crijns, Harry J.G.M., and van Gilst, Wiek H.

Published
2000
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20. Oral Contraceptive Use and Hormone Replacement Therapy Are Associated With Microalbuminuria.

Author

Monster, Taco B., Janssen, Wilbert M.T., de Jong, Paul E., and de Jong-van der Berg, Lolkje T.W.

Subjects
*ALBUMINURIA, *ORAL contraceptives, *HORMONE therapy for menopause, *PHYSIOLOGY
Abstract

Examines the association between oral contraceptive use or hormone replacement therapy (HRT) and microalbuminuria. Characteristics of women with microalbuminuria based on their menopausal status; Potential effects of HRT on cardiovascular morbidity and mortality.

Published
2001
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21. Psychosocial consequences of screening for albuminuria and certain other risk factors.

Author

Tymstra, Tjeerd, Spijkers, Edwin W., Broer, Jan, Janssen, Wilbert M.T., and de Jong, Paul E.

Subjects
DIAGNOSIS, ALBUMINURIA, HEALTH risk assessment
Abstract

Objective: To gain insight into the psychosocial consequences of a screening programme on the progression of heart, vascular and kidney damage. Design: Over 85,000 people aged 28–75 were invited to participate in a screening for albuminuria. Nearly half of them sent in their morning urine of which almost 10,000 had a (slightly) elevated urinary albumin level. This latter group was invited to participate in a follow-up screening (24-hour urine samples, blood pressure, glucose, cholesterol) together with ±3,000 randomly selected subjects with a normal urinary albumin concentration. A questionnaire on the psychosocial consequences of the screening was sent to 335 participants of the screening programme each of whom had received their (positive or negative) screening results two weeks previously. Results: The response rate was 75%. A minority of the respondents, diagnosed for risk factors, expressed some concern. No influence on the well-being of this group of participants could be established. Almost one third of the respondents claimed to follow a healthier lifestyle as a result of the screening. There are, however, also indications for a certain ‘certificate of health effect’: about half of the smokers and the physically inactive considered that the favourable screening results legitimated their unhealthy lifestyle. An unfavourable screening result led to additional medical consumption in almost half of the respondents. The respondents appreciated the screening and especially the less educated had a very positive attitude towards early diagnosis in general. Conclusions: Those screened positive showed no diminished well-being; their health behaviour improved because of the screening and their medical consumption increased. Many of those screened negative considered the test result a reason to continue their unhealthy lifestyle. [ABSTRACT FROM AUTHOR]

Published
2001

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