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Diabetes mellitus is one of the most common chronic diseases in children, and more than 90% of all diabetes cases in childhood is type 1 diabetes mellitus (T1DM). Several complications, including retinopathy, diabetic kidney disease, hypertension, cardiovascular autonomic, and peripheral sensory neuropathy, are associated with the onset of diabetes in childhood and represent a significant burden for the health care system. Diabetic autonomic neuropathy was defined as an autonomic nervous system disorder in diabetes or prediabetes after the exclusion of other causes, while diabetic peripheral neuropathy as a “symmetrical, lengthdependent sensorimotor polyneuropathy attributable to metabolic and microvessel alterations as a result of chronic hyperglycemia exposure (diabetes) and cardiovascular risk covariates. [ABSTRACT FROM AUTHOR]

The article talks about the consequences of an investigation of the actual properties of fluid and hydro alcoholic concentrations of dark currant during the interaction of focus in the evaporator, the rotating type. Relapse conditions of the impact of system boundaries of evaporator for fixation changes of dissolvable solids in the concentrates, it was uncovered that with expanding grouping of solvent solids in the concentrates of their thickness and consistency increment. The consistency of the concentrates is in direct extent to the liquor focus in the extracting and input from the cycle temperature, which is identified with the substance in the concentrated polyphenolic substances containing ionized gatherings causes the sub-atomic collaboration power is appalling. It is uncovered that because of cautious preparing mode extricates the concentration is portrayed by a high content of organically dynamic substances. Suggestions on the sane upsides of innovative boundaries and working states of the dissipation interaction in a slight film under vacuum, determined observational connections prescribed to utilize while ascertaining the evaporators rotational. [ABSTRACT FROM AUTHOR]

The study was conducted under plastic houses of the Department of Horticulture and Landscape Gardening at the College of Agriculture, Al-Qasim Green University, for the season (2017-2018) to study the effect of spraying with gibberellin, naphthalene, acetic acid and chelated zinc for three cultivars for Strawberry: RUBY GEM, Festival and Albion. The Randomized Complete Block Design (RCBD) was conducted with a Factorial Experiment (3×7) with three replicates and the experimental unit included one pot, for a total of 63 seedlings and the averages were compared to according to the test of less significant difference (L.S.D) under 5% probability level. The results showed that the spraying with gibberellin, Naphthalene acetic acid (NAA) and chelated zinc was significantly and gave the highest values for all studied traits. The (B2, K2, K1, B1) treatments were significantly was excelled in the rest of the treatments by giving it the highest average of this trait amounted to (22.97, 19.47, 19.45 and 18.15 leaf.plant-1), respectively. As for the trait of plant height, the treatments (B1, B2) were excelled by giving them an average amounted to (32.81, 30.80 cm), respectively. As for the trait of plant area, the treatment B2 was excelled by giving them an average amounted to 134.81 cm2. While the treatment of A2 was excelled by giving them an average of length of flower stalk amounted to 18.96 cm. The results showed that Albion cultivar (S3) was significantly excelled in traits the number of leaves, plant height and leaves area. The RUBY GEM cultivar was significantly excelled in the length of flower stalk. The results showed that Bi-interaction treatment (B2S3) was significantly excelled in traits the number of leaves, plant height and leaves area by giving them an average amounted to (24.48 leaf.pant-1, 37.12 cm, 138.12cm2), respectively. [ABSTRACT FROM AUTHOR]

Renal ischemia reperfusion injury promotes tissue damage through inducing uncontrolled inflammation, oxidative stress and excessive renal tubular epithelial cell death. Nrf2 pathway is essential in protecting the kidney against renal IRI. Canagliflozin is a sodium glucose co-transporter 2 (SGLT2) inhibitor, Canagliflozin attenuated nephrotoxicity possibly through its anti-inflammatory and antioxidant effects and may confer renoprotective effects independently of its glycemic effects. To study the Nephroprotective potential effect of Canagliflozin renal ischemia reperfusion injury in rats model via modulation of Nrf2 pathway. In this study, adult male rats of Westar Albino type with 18-28 weeks in age and weighing 300-350 g were randomized into equal four groups (6 rats each group) as following: Sham group, Control group, Vehicle (DMSO) group, Canagliflozin treated group. Rats were subject to bilateral renal ischemia for 30 min by clamping and reperfusion for 2 hr. We conclude that Canagliflozin significantly decrease renal ischemia reperfusion injury in rat model through Nrf2 pathway via it is pleiotropic effects as anti-oxidant, anti-inflammatory and anti-apoptotic. [ABSTRACT FROM AUTHOR]

The article looks at a study regarding cancer chemoprevention and the evidence of nonlinear dose response for the protective effects of resveratrol in humans and mice. It mentions efficacy correlated with activation of adenosine monophosphate–activated protein kinase (AMPK) and increased expression of the senescence marker. It also mentions expression of the cytoprotective NAD(P)H dehydrogenase, quinone 1 (NQO1) enzyme increased in tissues from cancer patients.