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1. Occult Uveitis-Glaucoma-Hyphema Syndrome Caused by PCIOL with Peripheral Capsular Tear

Author

Jason Dossantos, Yusuf Bade, Omar Halawa, Jasdeep Sabharwal, and Jella An

Subjects
cataract surgery, uveitis-glaucoma-hyphema syndrome, uveitis/inflammation, glaucoma, Ophthalmology, RE1-994
Abstract

Introduction: Uveitis-glaucoma-hyphema (UGH) syndrome is an infrequent but severe complication following intraocular lens implantation, characterized by anterior chamber inflammation and elevated intraocular pressure (IOP). This report presents a rare case of late-onset UGH syndrome induced by a well-positioned 1-piece posterior capsular intraocular lens (PCIOL) with a bulb of the haptics extruding through a peripheral capsular tear in a 90-year-old female, 17 years post-cataract surgery. Case Presentation: The patient presented with persistent blurred vision, recurrent anterior uveitis, and uncontrolled IOP despite medical therapy. Extensive evaluation, including ultrasound biomicroscopy, failed to identify the underlying cause, necessitating surgical intervention to control IOP. During concurrent goniotomy and canaloplasty, a PCIOL haptics was discovered protruding through a peripheral capsular tear, establishing the diagnosis. Following PCIOL-haptic amputation and goniotomy and canaloplasty, the patient experienced significant improvement in symptoms and IOP control, with complete resolution of UGH syndrome. Conclusion: This case highlights the necessity of considering atypical causes in persistent postoperative uveitis and IOP elevation and emphasizes the role of surgical intervention in managing complex cases.

Published
2024
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2. Outcomes of initial and repeat micro-pulse transscleral cyclophotocoagulation in adult glaucoma patients

Author

Sara Hooshmand, Jackson Voss, Matthew Hirabayashi, Lindsey McDaniel, and Jella An

Subjects
Ophthalmology, RE1-994
Abstract

Background: Micro-pulse transscleral cyclophotocoagulation (MP-TSCPC) has continued to gain popularity as a treatment in adult glaucoma patients. Thus far there is limited evidence reporting the efficaciousness and safety of retreatment. Objective: To evaluate safety and efficacy of primary and repeat MP-TSCPC procedures. Methods: Thirty-four of 67 eyes who failed to achieve target IOP from initial MP-TSCPC underwent repeat MP-TSCPC and followed for a minimum of 6 months. All treatments were performed using the laser power of 2000 or 2250 mW, duration of 100–200 s, and a velocity 16–20 s per hemisphere swipe. Success criteria were defined as intraocular pressure (IOP) reduction of greater than 20% from baseline or any medication reduction without additional glaucoma procedures at 6 months after repeat MP-TSCPC. The 6-month success rate after repeat MP-TSCPC was also compared to that of initial MP-TSCPC in the same group of eyes. Results: Mean baseline IOP before the repeat MP-TSCPC was 23.0 + /- 5.3 on 3.0 + /- 1.4 medications. At 6 months, mean post-op IOP was 18.2 + /- 5.4 (21.9% reduction, p

Published
2022
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3. An FBG-based Stiffness Estimation Sensor for In-vivo Diagnostics

Author

Moradkhani, Behnam, Kheradmand, Pejman, Jella, Harshith, Yamamoto, Kent K., Tofangchi, Alireza, Codd, Patrick J., and Chitalia, Yash

Subjects
Computer Science - Robotics
Abstract

In-vivo tissue stiffness identification can be useful in pulmonary fibrosis diagnostics and minimally invasive tumor identification, among many other applications. In this work, we propose a palpation-based method for tissue stiffness estimation that uses a sensorized beam buckled onto the surface of a tissue. Fiber Bragg Gratings (FBGs) are used in our sensor as a shape-estimation modality to get real-time beam shape, even while the device is not visually monitored. A mechanical model is developed to predict the behavior of a buckling beam and is validated using finite element analysis and bench-top testing with phantom tissue samples (made of PDMS and PA-Gel). Bench-top estimations were conducted and the results were compared with the actual stiffness values. Mean RMSE and standard deviation (from the actual stiffnesses) values of 413.86 KPa and 313.82 KPa were obtained. Estimations for softer samples were relatively closer to the actual values. Ultimately, we used the stiffness sensor within a mock concentric tube robot as a demonstration of \textit{in-vivo} sensor feasibility. Bench-top trials with and without the robot demonstrate the effectiveness of this unique sensing modality in \textit{in-vivo} applications., Comment: 6 pages (excluding the references), 5 figures

Published
2024

8. Hybrid Adaptive Systems

Author

Benke, Ivo, Knierim, Michael, Adam, Marc, Beigl, Michael, Dorner, Verena, Ebner-Priemer, Ulrich, Herrmann, Manfred, Klarmann, Martin, Maedche, Alexander, Nafziger, Julia, Nieken, Petra, Pfeiffer, Jella, Puppe, Clemens, Putze, Felix, Scheibehenne, Benjamin, Schultz, Tanja, and Weinhardt, Christof

Published
2024
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9. International Consensus Statement on Obstructive Sleep Apnea

Author

Chang, Jolie L, Goldberg, Andrew N, Alt, Jeremiah A, Mohammed, Alzoubaidi, Ashbrook, Liza, Auckley, Dennis, Ayappa, Indu, Bakhtiar, Hira, Barrera, José E, Bartley, Bethany L, Billings, Martha E, Boon, Maurits S, Bosschieter, Pien, Braverman, Itzhak, Brodie, Kara, Cabrera‐Muffly, Cristina, Caesar, Ray, Cahali, Michel B, Cai, Yi, Cao, Michelle, Capasso, Robson, Caples, Sean M, Chahine, Lana M, Chang, Corissa P, Chang, Katherine W, Chaudhary, Nilika, Cheong, Crystal SJ, Chowdhuri, Susmita, Cistulli, Peter A, Claman, David, Collen, Jacob, Coughlin, Kevin C, Creamer, Jennifer, Davis, Eric M, Dupuy‐McCauley, Kara L, Durr, Megan L, Dutt, Mohan, Ali, Mazen El, Elkassabany, Nabil M, Epstein, Lawrence J, Fiala, Justin A, Freedman, Neil, Gill, Kirat, Gillespie, M Boyd, Golisch, Lea, Gooneratne, Nalaka, Gottlieb, Daniel J, Green, Katherine K, Gulati, Arushi, Gurubhagavatula, Indira, Hayward, Nathan, Hoff, Paul T, Hoffmann, Oliver MG, Holfinger, Steven J, Hsia, Jennifer, Huntley, Colin, Huoh, Kevin C, Huyett, Phillip, Inala, Sanjana, Ishman, Stacey L, Jella, Tarun K, Jobanputra, Aesha M, Johnson, Andrew P, Junna, Mithri R, Kado, Jenna T, Kaffenberger, Thomas M, Kapur, Vishesh K, Kezirian, Eric J, Khan, Meena, Kirsch, Douglas B, Kominsky, Alan, Kryger, Meir, Krystal, Andrew D, Kushida, Clete A, Kuzniar, Thomas J, Lam, Derek J, Lettieri, Christopher J, Lim, Diane C, Lin, Hsin‐Ching, Liu, Stanley YC, MacKay, Stuart G, Magalang, Ulysses J, Malhotra, Atul, Mansukhani, Meghna P, Maurer, Joachim T, May, Anna M, Mitchell, Ron B, Mokhlesi, Babak, Mullins, Anna E, Nada, Eman M, Naik, Sreelatha, Nokes, Brandon, Olson, Michael D, Pack, Allan I, Pang, Edward B, Pang, Kenny P, Patil, Susheel P, Van de Perck, Eli, Piccirillo, Jay F, and Pien, Grace W

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Health Services, Lung, Sleep Research, Clinical Research, Prevention, Respiratory, Good Health and Well Being, Adult, Humans, Sleep Apnea, Obstructive, Continuous Positive Airway Pressure, Polysomnography, Risk Factors, atrial fibrillation, cardiovascular event, cerebrovascular disease, consensus, dementia, evidence-based medicine, home sleep apnea testing, hypertension, hypoglossal nerve stimulation, mortality, motor vehicle accidents, neurocognitive function, obstructive sleep apnea, outcomes, PAP adherence, perioperative management, polysomnography, positive airway pressure, screening, sleep, sleep disordered breathing, sleepiness, sleep surgery, surgical outcomes, systematic review, treatment outcomes, uvulopalatopharyngoplasty, Immunology, Clinical sciences
Abstract

BackgroundEvaluation and interpretation of the literature on obstructive sleep apnea (OSA) allows for consolidation and determination of the key factors important for clinical management of the adult OSA patient. Toward this goal, an international collaborative of multidisciplinary experts in sleep apnea evaluation and treatment have produced the International Consensus statement on Obstructive Sleep Apnea (ICS:OSA).MethodsUsing previously defined methodology, focal topics in OSA were assigned as literature review (LR), evidence-based review (EBR), or evidence-based review with recommendations (EBR-R) formats. Each topic incorporated the available and relevant evidence which was summarized and graded on study quality. Each topic and section underwent iterative review and the ICS:OSA was created and reviewed by all authors for consensus.ResultsThe ICS:OSA addresses OSA syndrome definitions, pathophysiology, epidemiology, risk factors for disease, screening methods, diagnostic testing types, multiple treatment modalities, and effects of OSA treatment on multiple OSA-associated comorbidities. Specific focus on outcomes with positive airway pressure (PAP) and surgical treatments were evaluated.ConclusionThis review of the literature consolidates the available knowledge and identifies the limitations of the current evidence on OSA. This effort aims to create a resource for OSA evidence-based practice and identify future research needs. Knowledge gaps and research opportunities include improving the metrics of OSA disease, determining the optimal OSA screening paradigms, developing strategies for PAP adherence and longitudinal care, enhancing selection of PAP alternatives and surgery, understanding health risk outcomes, and translating evidence into individualized approaches to therapy.

Published
2023

11. Customer Decision-Making Processes Revisited: Insights from an Eye Tracking and ECG Study Using a Hidden Markov Model

Author

Weiß, Tobias, Merkl, Lukas, Pfeiffer, Jella, Spagnoletti, Paolo, Series Editor, De Marco, Marco, Series Editor, Pouloudi, Nancy, Series Editor, Te'eni, Dov, Series Editor, vom Brocke, Jan, Series Editor, Winter, Robert, Series Editor, Baskerville, Richard, Series Editor, Za, Stefano, Series Editor, Braccini, Alessio Maria, Series Editor, Davis, Fred D., editor, Riedl, René, editor, Brocke, Jan vom, editor, Léger, Pierre-Majorique, editor, Randolph, Adriane B., editor, and Müller-Putz, Gernot R., editor

Published
2024
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13. Hybrid Adaptive Systems.

Author

Ivo Benke, Michael T. Knierim, Marc T. P. Adam, Michael Beigl, Verena Dorner, Ulrich Ebner-Priemer, Manfred Herrmann, Martin Klarmann, Alexander Maedche, Julia Nafziger, Petra Nieken, Jella Pfeiffer, Clemens Puppe, Felix Putze, Benjamin Scheibehenne, Tanja Schultz, and Christof Weinhardt

Published
2024
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39. Exosomes as Radiation Biomarkers

Author

Jella, Kishore Kumar, Wood, Michael D., editor, Mothersill, Carmel E., editor, Tsakanova, Gohar, editor, Cresswell, Tom, editor, and Woloschak, Gayle E., editor

Published
2022
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46. Pregnancy length and health in giant pandas: What can metabolic and urinary endocrine markers unveil?

Author

Wauters, Jella, Wilson, Kirsten S., Cools, Tom, Vancsok, Catherine, Bouts, Tim, Mulot, Baptiste, Leclerc, Antoine, Haapakoski, Marko, Kok, José, Kühne, Ragnar, Ochs, Andreas, Duncan, W. Colin, Girling, Simon J., Hildebrandt, Thomas B., Zhou, Qiang, Li, Rengui, Zhou, Yingmin, Cai, Kailai, Liu, Yuliang, Hou, Rong, Rae, Mick, Valentine, Iain, Vanhaecke, Lynn, and Li, Desheng

Published
2023
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