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36 results on '"Jenckel, Maria"'

2. First Detection of Benign Rabbit Caliciviruses in Chile

Author

Smertina, Elena, primary, Keller, Luca M., additional, Huang, Nina, additional, Flores-Benner, Gabriela, additional, Correa-Cuadros, Jennifer Paola, additional, Duclos, Melanie, additional, Jaksic, Fabian M., additional, Briceño, Cristóbal, additional, Ramirez, Victor Neira, additional, Díaz-Gacitúa, Miguel, additional, Carrasco-Fernández, Sebastián, additional, Smith, Ina L., additional, Strive, Tanja, additional, and Jenckel, Maria, additional

Published
2024
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3. Utilizing Molecular Epidemiology and Citizen Science for the Surveillance of Lagoviruses in Australia

Author

Peng, Nias Y. G., primary, Hall, Robyn N., additional, Huang, Nina, additional, West, Peter, additional, Cox, Tarnya E., additional, Mahar, Jackie E., additional, Mason, Hugh, additional, Campbell, Susan, additional, O’Connor, Tiffany, additional, Read, Andrew J., additional, Patel, Kandarp K., additional, Taggart, Patrick L., additional, Smith, Ina L., additional, Strive, Tanja, additional, and Jenckel, Maria, additional

Published
2023
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6. Variegated squirrel bornavirus 1 in squirrels, Germany and the Netherlands

Author

Schlottau, Kore, Jenckel, Maria, van den Brand, Judith, Fast, Christine, Herden, Christiane, Hoper, Dirk, Homeier-Bachmann, Timo, Thielebein, Jens, Mensing, Niels, Diender, Bert, Hoffmann, Donata, Ulrich, Rainer G., Mettenleiter, Thomas C., Koopmans, Marion, Tappe, Dennis, Schmidt-Chanasit, Jonas, Reusken, Chantal B.E.M., Beer, Martin, and Hoffmann, Bernd

Subjects
RNA viruses -- Distribution, Human-animal relationships, Zoonoses -- Risk factors, Squirrels -- Health aspects, Company distribution practices, Health
Abstract

The family Bornaviridae comprises the classical mammalian bornaviruses (Mammalian 1 bornavirus with borna disease virus; BoDV-1 and -2); avian bornaviruses (Passeriform 1/2 bornavirus, Psittaciform 1/2 bornavirus, Waterbird 1 bornavirus); and [...]

Published
2017
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9. Lagovirus Non-structural Protein p23: A Putative Viroporin That Interacts With Heat Shock Proteins and Uses a Disulfide Bond for Dimerization

Author

Smertina, Elena, primary, Carroll, Adam J., additional, Boileau, Joseph, additional, Emmott, Edward, additional, Jenckel, Maria, additional, Vohra, Harpreet, additional, Rolland, Vivien, additional, Hands, Philip, additional, Hayashi, Junna, additional, Neave, Matthew J., additional, Liu, Jian-Wei, additional, Hall, Robyn N., additional, Strive, Tanja, additional, and Frese, Michael, additional

Published
2022
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11. Comparison of porcine epidemic diarrhea viruses from Germany and the United States, 2014

Author

Hanke, Dennis, Jenckel, Maria, Petrov, Anja, Ritzmann, Mathias, Stadler, Julia, Akimkin, Valerij, Blome, Sandra, Pohlmann, Anne, Schirrmeier, Horst, Beer, Martin, and Hoper, Dirk

Subjects
Epidemics -- Germany -- Analysis, Virulence (Microbiology) -- Analysis, Genomics -- Analysis, Swine -- Analysis, Diarrhea -- Analysis, Pork industry -- Analysis, Livestock farms -- Analysis, Health
Abstract

Porcine epidemic diarrhea (PED) is an acute and highly contagious enteric disease of swine that results in severe enteritis, diarrhea, vomiting, and dehydration (1). Porcine epidemic diarrhea virus (PEDV), the [...]

Published
2015
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15. Novel bluetongue virus in goats, Corsica, France, 2014

Author

Zientara, Stephan, Sailleau, Corinne, Viarouge, Cyril, Hoper, Dirck, Beer, Martin, Jenckel, Maria, Hoffmann, Bernd, Romey, Aurore, Bakkali-Kassimi, Labib, Fablet, Aurore, Vitour, Damien, and Breard, Emmanuel

Subjects
Animals -- Diseases, Medical research, Medicine, Experimental, Genotype -- Identification and classification, RNA virus infections -- Genetic aspects, Health
Abstract

Bluetongue is an infectious, noncontagious, arthropodborne viral disease of domestic and wild ruminants (1). Twenty-six distinct bluetongue virus (BTV) serotypes have been identified (2). The first detection of bluetongue virus [...]

Published
2014
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16. MOESM1 of Investigations into the presence of nidoviruses in pythons

Author

Blahak, Silvia, Jenckel, Maria, HöPer, Dirk, Beer, Martin, Hoffmann, Bernd, and Kore Schlottau

Abstract

Additional file 1: Table S1. Comparison of the newly developed real-time RT-PCRs with the one published by Dervas et al. (positive samples). Table S2. Sequence identity between all in this study generated partial sequences. Figure S1. Genome organization of snake nidoviruses. Sequences marked in red were generated within this study.

Published
2020
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19. Camelids and Cattle Are Dead-End Hosts for Peste-des-Petits-Ruminants Virus

Author

Schulz, Claudia, primary, Fast, Christine, additional, Wernery, Ulrich, additional, Kinne, Jörg, additional, Joseph, Sunitha, additional, Schlottau, Kore, additional, Jenckel, Maria, additional, Höper, Dirk, additional, Patteril, Nissy Annie Georgy, additional, Syriac, Ginu, additional, Hoffmann, Bernd, additional, and Beer, Martin, additional

Published
2019
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20. Characterization of bluetongue virus serotype 28

Author

Bumbarov, Velizar, primary, Golender, Natalia, additional, Jenckel, Maria, additional, Wernike, Kerstin, additional, Beer, Martin, additional, Khinich, Evgeny, additional, Zalesky, Olga, additional, and Erster, Oran, additional

Published
2019
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21. Epidemiological Investigations of Four Cowpox Virus Outbreaks in Alpaca Herds, Germany

Author

Prkno, Almut, Hoffmann, Donata, Goerigk, Daniela, Kaiser, Matthias, van Maanen, Anne Catherine Franscisca, Jeske, Kathrin, Jenckel, Maria, Pfaff, Florian, Vahlenkamp, Thomas W., Beer, Martin, Ulrich, Rainer G., Starke, Alexander, and Pfeffer, Martin

Subjects
spill-over infection, common vole (Microtus arvalis), Arvicolinae, South American camelids, lcsh:QR1-502, Cowpox, cowpox virus, Orthopoxvirus, zoonosis, Antibodies, Viral, Polymerase Chain Reaction, Article, lcsh:Microbiology, Disease Outbreaks, Seroepidemiologic Studies, Germany, Zoonoses, Animals, reservoir host, Camelids, New World, Phylogeny, Disease Reservoirs
Abstract

Four cowpox virus (CPXV) outbreaks occurred in unrelated alpaca herds in Eastern Germany during 2012–2017. All incidents were initially noticed due to severe, generalized, and finally lethal CPXV infections, which were confirmed by testing of tissue and serum samples. As CPXV-infection has been described in South American camelids (SACs) only three times, all four herds were investigated to gain a deeper understanding of CPXV epidemiology in alpacas. The different herds were investigated twice, and various samples (serum, swab samples, and crusts of suspicious pox lesions, feces) were taken to identify additionally infected animals. Serum was used to detect CPXV-specific antibodies by performing an indirect immunofluorescence assay (iIFA); swab samples, crusts, and feces were used for detection of CPXV-specific DNA in a real-time PCR. In total, 28 out of 107 animals could be identified as affected by CPXV, by iIFA and/or PCR. Herd seroprevalence ranged from 16.1% to 81.2%. To investigate the potential source of infection, wild small mammals were trapped around all alpaca herds. In two herds, CPXV-specific antibodies were found in the local rodent population. In the third herd, CPXV could be isolated from a common vole (Microtus arvalis) found drowned in a water bucket used to water the alpacas. Full genome sequencing and comparison with the genome of a CPXV from an alpaca from the same herd reveal 99.997% identity, providing further evidence that the common vole is a reservoir host and infection source of CPXV. Only in the remaining fourth herd, none of the trapped rodents were found to be CPXV-infected. Rodents, as ubiquitous reservoir hosts, in combination with increasingly popular alpacas, as susceptible species, suggest an enhanced risk of future zoonotic infections.

Published
2017

22. New chimeric porcine coronavirus in swine feces, Germany, 2012

Author

Akimkin, Valerij, Beer, Martin, Blome, Sandra, Hanke, Dennis, Hoper, Dirk, Jenckel, Maria, and Pohlmann, Anne

Subjects
Gastroenteritis -- Health aspects -- Analysis, Diarrhea -- Health aspects -- Analysis, Pork industry -- Health aspects -- Analysis, Health
Abstract

To the Editor: Porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV) can cause severe enteritis in pigs accompanied by diarrhea, vomiting, and dehydration. Clinical signs are most prominent [...]

Published
2016

23. Characterization of bluetongue virus serotype 28.

Author

Bumbarov, Velizar, Golender, Natalia, Jenckel, Maria, Wernike, Kerstin, Beer, Martin, Khinich, Evgeny, Zalesky, Olga, and Erster, Oran

Subjects
BLUETONGUE virus, RHINITIS, SYMPTOMS, CERATOPOGONIDAE, NUCLEOTIDE sequence, ACUTE diseases, BODY temperature
Abstract

Bluetongue virus (Reoviridae; Orbivirus, BTV), which is usually transmitted by biting midges, affects wild and domestic ruminants worldwide, thereby causing an economically important disease. Recently, a putative new BTV strain was isolated from contaminated vaccine batches. In this study, we investigated the genomic and clinical characteristics of this isolate, provisionally designated BTV‐28. Phylogenetic analysis of BTV‐28 segment 2 (Seg‐2) showed that it is related to Seg‐2 from BTV serotypes 4, 10, 11, 17, 20 and 24, sharing 64%–66% identity in nucleotide sequences (nt) and 59%–62% in amino acid (aa) sequences of BTV VP2. BTV‐28 Seg‐6 is related to the newly reported XJ1407 BTV isolate, sharing 76.70% nt and 90.87% aa sequence identity. Seg‐5 was most closely related to a South African BTV‐4 strain, and all other segments showed close similarity to BTV‐26. Experimental infection by injection of 6‐month‐old ewes caused clinical signs in all injected animals, lasting from 2 to 3 days to several weeks post‐infection, including high body temperature, conjunctivitis, nasal discharge and rhinitis, facial oedema, oral hyperaemia, coronitis, cough, depression and tongue cyanosis. Naïve control animals, placed together with the infected sheep, displayed clinical signs and were positive for viral RNA, but their acute disease phase was shorter than that of BTV‐injected ewes. Control animals that were kept in a separated pen did not display any clinical signs and were negative for viral RNA presence throughout the experiment. Seroconversion was observed in the injected and in one of the two contact‐infected animals. These findings demonstrate that BTV‐28 infection of sheep can result in clinical manifestation, and the clinical signs detected in the contact animals suggest that it might be directly transmitted between the mammalian hosts. [ABSTRACT FROM AUTHOR]

Published
2020
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27. Bluetongue virus serotype 27: detection and characterization of two novel variants in Corsica, France

Author

Schulz, Claudia, primary, Bréard, Emmanuel, additional, Sailleau, Corinne, additional, Jenckel, Maria, additional, Viarouge, Cyril, additional, Vitour, Damien, additional, Palmarini, Massimo, additional, Gallois, Mélanie, additional, Höper, Dirk, additional, Hoffmann, Bernd, additional, Beer, Martin, additional, and Zientara, Stéphan, additional

Published
2016
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29. Out of the Reservoir: Phenotypic and Genotypic Characterization of a Novel Cowpox Virus Isolated from a Common Vole

Author

Hoffmann, Donata, primary, Franke, Annika, additional, Jenckel, Maria, additional, Tamošiūnaitė, Aistė, additional, Schluckebier, Julia, additional, Granzow, Harald, additional, Hoffmann, Bernd, additional, Fischer, Stefan, additional, Ulrich, Rainer G., additional, Höper, Dirk, additional, Goller, Katja, additional, Osterrieder, Nikolaus, additional, and Beer, Martin, additional

Published
2015
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30. Complete Genome Sequence of Avian Paramyxovirus Strain APMV-6/red-crested pochard/Balkhash/5842/2013 from Kazakhstan

Author

Karamendin, Kobey, primary, Kydyrmanov, Aidyn, additional, Seidalina, Aigerim, additional, Jenckel, Maria, additional, Starick, Elke, additional, Grund, Christian, additional, Asanova, Saule, additional, Khan, Elizaveta, additional, Daulbayeva, Klara, additional, Kasymbekov, Yermukhammet, additional, Zhumatov, Kainar, additional, Sayatov, Marat, additional, Beer, Martin, additional, and Fereidouni, Sasan, additional

Published
2015
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35. Preparation of modified long-mer RNAs and analysis of FMN binding to the ypaAaptamer from B. subtilis

Author

Frommer, Jennifer, Hieronymus, Robert, Selvi Arunachalam, Tamil, Heeren, Sabine, Jenckel, Maria, Strahl, Anne, Appel, Bettina, and Müller, Sabine

Abstract

In recent years, RNA has been shown to fulfil a number of cellular functions. This has led to much interest in elucidation of the structure of functional RNA molecules, and thus, in the preparation of suitably functionalized RNAs. The chemical synthesis of RNAs allows for the site-specific modification; however, is limited to sequences of about 60–70 nucleotides in length. At the example of the flavine mononucleotide (FMN) responsive aptamer of the ypaAriboswitch from B. subtilis, we demonstrate the highly efficient preparation of site-specifically modified long-mer RNAs. Our strategy consists of the chemical synthesis of fragments followed by enzymatic or chemical ligation. Splint ligation with T4 RNA ligase turned out to be most successful among the enyzymatic protocols. Highly efficient chemical ligation was performed by azide–alkyne cycloaddition of suitably modified RNA fragments. Wild-type and 2-aminopurine (2-AP)-modified variants of the ypaAaptamer were prepared. FMN binding to all synthesized ypaAaptamer variants is demonstrated. However, dissociation of FMN from its binding site by reduction of the isoalloxazin unit as demonstrated before for a small-hairpin-derived aptazyme could not be shown. This implies that either FMN is less accessible to reduction when it is bound to its natural aptamer; that reduced FMN remains bound to the aptamer; or that FMN upon reduction indeed is released from its binding site, without the aptamer folding back in the natural ligand-free state. The results of this study are of general interest to the preparation of site-specifically modified RNAs for investigation into structure and function.

Published
2014
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36. Fatal Cowpox Virus Infection in an Aborted Foal.

Author

Franke A, Kershaw O, Jenckel M, König L, Beer M, Hoffmann B, and Hoffmann D

Subjects
Animals, Cowpox pathology, Cowpox virology, Cowpox virus genetics, Fatal Outcome, Genome, Viral, Horse Diseases pathology, Horses, Phylogeny, Abortion, Veterinary, Cowpox veterinary, Cowpox virus isolation & purification, Fetus virology, Horse Diseases virology
Abstract

The article describes the isolation of a cowpox virus (CPXV) isolate originating from a horse. The skin of a foal, aborted in the third trimester, displayed numerous cutaneous papules. The histological examination showed A-type inclusion bodies within the lesion, typical for CPXV infections. This suspicion was confirmed by real-time PCR where various organs were analyzed. From skin samples, virus isolation was successfully performed. Afterwards, the whole genome of this new isolate "CPXV Amadeus" was sequenced by next-generation technology. Phylogenetic analysis clearly showed that "CPXV Amadeus" belongs to the "CPXV-like 1" clade. To our opinion, the study provides important additional information on rare accidental CPXV infections. From the natural hosts, the voles, species such as rats, cats, or different zoo animals are occasionally infected, but until now only two horse cases are described. In addition, there are new insights toward congenital CPXV infections.

Published
2016
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