1. Post-discharge health status and symptoms in patients with severe COVID-19
- Author
-
Hannah C. Karpel, Kanan Shah, Tamara Kahan, Himali Weerahandi, Caroline Blaum, Katherine Hochman, Leora I. Horwitz, Joshua Chodosh, Sneha Sharma, Emma Simon, Ana Z. Stirniman, Emily Duan, Felicia Mendoza, Jennifer Rutishauser, Kira Garry, Lindsey Quintana, Elias Simon, Savannah Karmen-Tuohy, Alexander M Prete, and Leticia Santos Martinez
- Subjects
Male ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Post discharge ,Population ,Aftercare ,Discharged alive ,Disease ,01 natural sciences ,Article ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,COVID-19 Testing ,Interquartile range ,Internal medicine ,Internal Medicine ,Humans ,Medicine ,In patient ,030212 general & internal medicine ,Prospective Studies ,0101 mathematics ,Statistics & numerical data ,education ,Prospective cohort study ,Original Research ,Aged ,education.field_of_study ,business.industry ,010102 general mathematics ,COVID-19 ,Middle Aged ,Respiration, Artificial ,Mental health ,Patient Discharge ,Mental Health ,Disease Progression ,Observational study ,Female ,business ,Cohort study - Abstract
BackgroundLittle is known about long-term recovery from severe COVID-19 disease. Here, we characterize overall health, physical health and mental health of patients one month after discharge for severe COVID-19.MethodsThis was a prospective single health system observational cohort study of patients ≥18 years hospitalized with laboratory-confirmed COVID-19 disease who required at least 6 liters of oxygen during admission, had intact baseline cognitive and functional status and were discharged alive. Participants were enrolled between 30 and 40 days after discharge. Outcomes were elicited through validated survey instruments: the PROMIS® Dyspnea Characteristics and PROMIS® Global Health-10.ResultsA total of 161 patients (40.6% of eligible) were enrolled; 152 (38.3%) completed the survey. Median age was 62 years (interquartile range [IQR], 50-67); 57 (37%) were female. Overall, 113/152 (74%) participants reported shortness of breath within the prior week (median score 3 out of 10 [IQR 0-5]), vs. 47/152 (31%) pre-COVID-19 infection (0, IQR 0-1), pConclusionsPatients with severe COVID-19 disease typically experience sequelae affecting their respiratory status, physical health and mental health for at least several weeks after hospital discharge.
- Published
- 2020
- Full Text
- View/download PDF