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1. First Steps towards a Mental Health and Neurodevelopmental Screening of Secondary School Children Following Two Fixed-Term School Exclusions in the UK

Author

Lawson, Caron, Prentice, Kate, Jennings, Janine, and Johnston, Kate

Abstract

Children excluded from school often have a range of unidentified needs that may directly contribute to their behaviour. Research and policy highlight the absence of screening for difficulties in children at risk of exclusion. This study aimed to assess and explore the feasibility and acceptability of neurodevelopmental and mental health screening of secondary school children with two or more fixed-term exclusions, as well as compare differences in rates to matched controls. Mental health and neurodevelopmental measures were collected from 40 children aged 11-16, 13 parents and 9 teachers. The screening process was feasible and acceptable for the children, however there was limited informant response. Case participants showed elevated levels across all screening measures compared to matched control participants. This study highlights the range of difficulties experienced by children at risk of exclusion from school and suggests a screening process may help to identify underlying neurodevelopmental and mental health difficulties.

Published
2022
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2. Association of Accelerometry‐Measured Physical Activity and Cardiovascular Events in Mobility‐Limited Older Adults: The LIFE (Lifestyle Interventions and Independence for Elders) Study

Author

Cochrane, Shannon K, Chen, Shyh‐Huei, Fitzgerald, Jodi D, Dodson, John A, Fielding, Roger A, King, Abby C, McDermott, Mary M, Manini, Todd M, Marsh, Anthony P, Newman, Anne B, Pahor, Marco, Tudor‐Locke, Catrine, Ambrosius, Walter T, Buford, Thomas W, Espeland, Mark A, Applegate, William, Beavers, Daniel P, Byington, Robert P, Cook, Delilah, Furberg, Curt D, Harvin, Lea N, Henkin, Leora, Hepler, John, Hsu, Fang‐Chi, Lovato, Laura, Roberson, Wesley, Rushing, Julia, Rushing, Scott, Stowe, Cynthia L, Walkup, Michael P, Hire, Don, Rejeski, W Jack, Katula, Jeffrey A, Brubaker, Peter H, Mihalko, Shannon L, Jennings, Janine M, Pierce, June J, Romashkan, Sergei, Patel, Kushang V, Bonds, Denise, Spring, Bonnie, Hauser, Joshua, Kerwin, Diana, Domanchuk, Kathryn, Graff, Rex, Rego, Alvito, Blair, Steven N, Myers, Valerie H, Monce, Ron, Britt, Nathan E, Harris, Melissa Nauta, McGucken, Ami Parks, Rodarte, Ruben, Millet, Heidi K, Butitta, Ben P, Donatto, Sheletta G, Cocreham, Shannon H, Castro, Cynthia M, Haskell, William L, Stafford, Randall S, Pruitt, Leslie A, Berra, Kathy, Yank, Veronica, Anton, Stephen D, Nayfield, Susan, Marsiske, Michael, Sandesara, Bhanuprasad D, Knaggs, Jeffrey D, Lorow, Megan S, Marena, William C, Korytov, Irina, Morris, Holly L, Fitch, Margo, Singletary, Floris F, Causer, Jackie, Radcliff, Katie A, Studenski, Stephanie A, Goodpaster, Bret H, Glynn, Nancy W, Lopez, Oscar, Nadkarni, Neelesh K, Williams, Kathy, Newman, Mark A, Grove, George, Bonk, Janet T, Rush, Jennifer, Kost, Piera, Ives, Diane G, Brinkley, Tina E, Demons, Jamehl S, Sink, Kaycee M, Kennedy, Kimberly, Shertzer‐Skinner, Rachel, Wrights, Abbie, Fries, Rose, Barr, Deborah, Axtell, Robert S, Kashaf, Susan S, de Rekeneire, Nathalie, and McGloin, Joanne M

Subjects
Aging, Cardiovascular, Prevention, Clinical Research, 3.1 Primary prevention interventions to modify behaviours or promote wellbeing, Prevention of disease and conditions, and promotion of well-being, Actigraphy, Age Factors, Aged, Aged, 80 and over, Cardiovascular Diseases, Exercise, Exercise Therapy, Female, Fitness Trackers, Geriatric Assessment, Health Knowledge, Attitudes, Practice, Humans, Incidence, Male, Mobility Limitation, Patient Education as Topic, Predictive Value of Tests, Prognosis, Protective Factors, Risk Factors, Risk Reduction Behavior, Time Factors, United States, LIFE Study Research Group, accelerometry, aging, cardiovascular, physical activity, Cardiorespiratory Medicine and Haematology
Abstract

BACKGROUND:Data are sparse regarding the value of physical activity (PA) surveillance among older adults-particularly among those with mobility limitations. The objective of this study was to examine longitudinal associations between objectively measured daily PA and the incidence of cardiovascular events among older adults in the LIFE (Lifestyle Interventions and Independence for Elders) study. METHODS AND RESULTS:Cardiovascular events were adjudicated based on medical records review, and cardiovascular risk factors were controlled for in the analysis. Home-based activity data were collected by hip-worn accelerometers at baseline and at 6, 12, and 24 months postrandomization to either a physical activity or health education intervention. LIFE study participants (n=1590; age 78.9±5.2 [SD] years; 67.2% women) at baseline had an 11% lower incidence of experiencing a subsequent cardiovascular event per 500 steps taken per day based on activity data (hazard ratio, 0.89; 95% confidence interval, 0.84-0.96; P=0.001). At baseline, every 30 minutes spent performing activities ≥500 counts per minute (hazard ratio, 0.75; confidence interval, 0.65-0.89 [P=0.001]) were also associated with a lower incidence of cardiovascular events. Throughout follow-up (6, 12, and 24 months), both the number of steps per day (per 500 steps; hazard ratio, 0.90, confidence interval, 0.85-0.96 [P=0.001]) and duration of activity ≥500 counts per minute (per 30 minutes; hazard ratio, 0.76; confidence interval, 0.63-0.90 [P=0.002]) were significantly associated with lower cardiovascular event rates. CONCLUSIONS:Objective measurements of physical activity via accelerometry were associated with cardiovascular events among older adults with limited mobility (summary score >10 on the Short Physical Performance Battery) both using baseline and longitudinal data. CLINICAL TRIAL REGISTRATION:URL: http://www.clinicaltrials.gov. Unique identifier: NCT01072500.

Published
2017

3. Dynapenia and Metabolic Health in Obese and Nonobese Adults Aged 70 Years and Older: The LIFE Study

Author

Gill, Thomas, Fragoso, Carlos, Fielding, Roger, Hauser, Michelle E., Pahor, Marco, Guralnik, Jack M., Leeuwenburgh, Christiaan, Caudle, Connie, Crump, Lauren, Holmes, Latonia, Lee, Jocelyn, Lu, Ching-ju, Miller, Michael E., Espeland, Mark A., Ambrosius, Walter T., Applegate, William, Beavers, Daniel P., Byington, Robert P., Cook, Delilah, Furberg, Curt D., Harvin, Lea N., Henkin, Leora, Hepler, Med John, Hsu, Fang-Chi, Lovato, Laura, Roberson, Wesley, Rushing, Julia, Rushing, Scott, Stowe, Cynthia L., Walkup, Michael P., Hire, Don, Rejeski, W. Jack, Katula, Jeffrey A., Brubaker, Peter H., Mihalko, Shannon L., Jennings, Janine M., Hadley, Evan C., Romashkan, Sergei, Patel, Kushang V., Bonds, Denise, McDermott, Mary M., Spring, Bonnie, Hauser, Joshua, Kerwin, Diana, Domanchuk, Kathryn, Graff, Rex, Rego, Alvito, Church, Timothy S., Blair, Steven N., Myers, Valerie H., Monce, Ron, Britt, Nathan E., Harris, Melissa Nauta, McGucken, Ami Parks, Rodarte, Ruben, Millet, Heidi K., Tudor-Locke, Catrine, Butitta, Ben P., Donatto, Sheletta G., Cocreham, Shannon H., King, Abby C., Castro, Cynthia M., Haskell, William L., Stafford, Randall S., Pruitt, Leslie A., Berra, Kathy, Yank, Veronica, Fielding, Roger A., Nelson, Miriam E., Folta, Sara C., Phillips, Edward M., Liu, Christine K., McDavitt, Erica C., Reid, Kieran F., Kirn, Dylan R., Pasha, Evan P., Kim, Won S., Beard, Vince E., Tsiroyannis, Eleni X., Hau, Cynthia, Manini, Todd M., Anton, Stephen D., Nayfield, Susan, Buford, Thomas W., Marsiske, Michael, Sandesara, Bhanuprasad D., Knaggs, Jeffrey D., Lorow, Megan S., Marena, William C., Korytov, Irina, Morris, Holly L., Fitch, Margo, Singletary, Floris F., Causer, Jackie, Radcliff, Katie A., Newman, Anne B., Studenski, Stephanie A., Goodpaster, Bret H., Glynn, Nancy W., Lopez, Oscar, Nadkarni, Neelesh K., Williams, Kathy, Newman, Mark A., Grove, George, Bonk, Janet T., Rush, Jennifer, Kost, Piera, Ives, Diane G., Kritchevsky, Stephen B., Marsh, Anthony P., Brinkley, Tina E., Demons, Jamehl S., Sink, Kaycee M., Kennedy, Kimberly, Shertzer-Skinner, Rachel, Wrights, Abbie, Fries, Rose, Barr, Deborah, Gill, Thomas M., Axtell, Robert S., Kashaf, Susan S., de Rekeneire, Nathalie, McGloin, Joanne M., Wu, Karen C., Shepard, Denise M., Fennelly, Barbara, Iannone, Lynne P., Mautner, Raeleen, Barnett, Theresa Sweeney, Halpin, Sean N., Brennan, Matthew J., Bugaj, Julie A., Zenoni, Maria A., Mignosa, Bridget M., Williamson, Jeff, Hendrie, Hugh C., Rapp, Stephen R., Verghese, Joe, Woolard, Nancy, Espeland, Mark, Jennings, Janine, Wilson, Valerie K., Pepine, Carl J., Ariet, Mario, Handberg, Eileen, Deluca, Daniel, Hill, James, Szady, Anita, Chupp, Geoffrey L., Flynn, Gail M., Hankinson, John L., Vaz Fragoso, Carlos A., Groessl, Erik J., Kaplan, Robert M., Aubertin-Leheudre, Mylène, Anton, Stephen, Newman, Ann, Church, Tim, Conroy, David, and Botoseneanu, Anda

Published
2017
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4. Predictors of Change in Physical Function in Older Adults in Response to Long-Term, Structured Physical Activity: The LIFE Study

Author

Pahor, Marco, Guralnik, Jack M., Leeuwenburgh, Christiaan, Caudle, Connie, Crump, Lauren, Holmes, Latonia, Lee, Jocelyn, Lu, Ching-ju, Miller, Michael E., Espeland, Mark A., Ambrosius, Walter T., Applegate, William, Beavers, Daniel P., Byington, Robert P., Cook, Delilah, Furberg, Curt D., Harvin, Lea N., Henkin, Leora, Hepler, John, Hsu, Fang-Chi, Lovato, Laura, Roberson, Wesley, Rushing, Julia, Rushing, Scott, Stowe, Cynthia L., Walkup, Michael P., Hire, Don, Rejeski, W. Jack, Katula, Jeffrey A., Brubaker, Peter H., Mihalko, Shannon L., Jennings, Janine M., Hadley, Evan C., Romashkan, Sergei, Patel, Kushang V., Bonds, Denise, McDermott, Mary M., Spring, Bonnie, Hauser, Joshua, Kerwin, Diana, Domanchuk, Kathryn, Graff, Rex, Rego, Alvito, Church, Timothy S., Blair, Steven N., Myers, Valerie H., Monce, Ron, Britt, Nathan E., Harris, Melissa Nauta, McGucken, Ami Parks, Rodarte, Ruben, Millet, Heidi K., Tudor-Locke, Catrine, Butitta, Ben P., Donatto, Sheletta G., Cocreham, Shannon H., King, Abby C., Castro, Cynthia M., Haskell, William L., Stafford, Randall S., Pruitt, Leslie A., Berra, Kathy, Yank, Veronica, Fielding, Roger A., Nelson, Miriam E., Folta, Sara C., Phillips, Edward M., Liu, Christine K., McDavitt, Erica C., Reid, Kieran F., Kim, Won S., Beard, Vince E., Manini, Todd M., Anton, Stephen D., Nayfield, Susan, Buford, Thomas W., Marsiske, Michael, Sandesara, Bhanuprasad D., Knaggs, Jeffrey D., Lorow, Megan S., Marena, William C., Korytov, Irina, Morris, Holly L., Fitch, Margo, Singletary, Floris F., Causer, Jackie, Radcliff, Katie A., Newman, Anne B., Studenski, Stephanie A., Goodpaster, Bret H., Glynn, Nancy W., Lopez, Oscar, Nadkarni, Neelesh K., Williams, Kathy, Newman, Mark A., Grove, George, Bonk, Janet T., Rush, Jennifer, Kost, Piera, Ives, Diane G., Kritchevsky, Stephen B., Marsh, Anthony P., Brinkley, Tina E., Demons, Jamehl S., Sink, Kaycee M., Kennedy, Kimberly, Shertzer-Skinner, Rachel, Wrights, Abbie, Fries, Rose, Barr, Deborah, Gill, Thomas M., Axtell, Robert S., Kashaf, Susan S., de Rekeneire, Nathalie, McGloin, Joanne M., Wu, Karen C., Shepard, Denise M., Fennelly, Barbara, Iannone, Lynne P., Mautner, Raeleen, Barnett, Theresa Sweeney, Halpin, Sean N., Brennan, Matthew J., Bugaj, Julie A., Zenoni, Maria A., Mignosa, Bridget M., Williamson, Jeff, Hendrie, Hugh C., Rapp, Stephen R., Verghese, Joe, Woolard, Nancy, Espeland, Mark, Jennings, Janine, Pepine, Carl J., Ariet, Mario, Handberg, Eileen, Deluca, Daniel, Hill, James, Szady, Anita, Chupp, Geoffrey L., Flynn, Gail M., Hankinson, John L., Vaz Fragoso, Carlos A., Groessl, Erik J., Kaplan, Robert M., Layne, Andrew S., Chen, Shyh-Huei, Dungan, Jennifer, Hajduk, Alexandra M., and Pellegrini, Christine A.

Published
2017
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5. Recollection Training and Transfer Effects in Alzheimer's Disease: Effectiveness of the Repetition-Lag Procedure

Author

Boller, Benjamin, Jennings, Janine M., and Dieudonne, Benedicte

Abstract

Objective: This study was designed to extend the use of a memory training technique, known as the repetition-lag procedure, to Alzheimer patients. The specificity of this procedure is to target the process of recollection for improvement. Method: A group of 12 patients were trained individually for 6 h. The training procedure consisted of a series of yes/no recognition tasks in which some words were repeated throughout the test list across gradually increasing delays. Their performance was evaluated on pre-and-post tests and compared with a recognition practice group and a no contact control group. Results: Initially, recollection training patients only performed accurately when the delay between repetitions consisted of one intervening word, but by the end of training their performance increased up to four-word intervals. Interestingly, these benefits generalized to other measures of memory, such as working memory, visual memory and source recognition. Conclusions: Effectiveness of the repetition-lag procedure in Alzheimer's disease is discussed. (Contains 2 figures and 4 tables.)

Published
2012
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8. Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial

Author

Sink, Kaycee M., Espeland, Mark A., Castro, Cynthia M., Church, Timothy, Cohen, Ron, Dodson, John A., Guralnik, Jack, Hendrie, Hugh C., Jennings, Janine, Katula, Jeffery, Lopez, Oscar L., McDermott, Mary M., Pahor, Marco, Reid, Kieran F., Rushing, Julia, Verghese, Joe, Rapp, Stephen, and Williamson, Jeff D.

Published
2015
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14. An opposition procedure for detecting age-related deficits in recollection: telling effects of repetition

Author

Jennings, Janine M. and Jacoby, Larry L.

Subjects
Aged -- Psychological aspects, Memory in old age -- Research, Psychology and mental health, Seniors
Abstract

Older adults tend to repeat themselves due to problems with recollection. Stories tend to be repeated unless there is a conscious memory of having told them. Age-related recollection deficits can be measured by assessing the time it takes for repetition errors to arise. Older adults showed a marked difference in their performance on this test. This research backs previous findings where older adults were less able to classify test items in terms of how often they had been presented.

Published
1997

17. Designing clinical trials for assessing the effects of cognitive training and physical activity interventions on cognitive outcomes: The Seniors Health and Activity Research Program Pilot (SHARP-P) Study, a randomized controlled trial

Author

Rejeski W Jack, Rapp Stephen R, Sink Kaycee M, Dagenbach Dale, Gaussoin Sarah A, Katula Jeffrey A, Jennings Janine M, Legault Claudine, Shumaker Sally A, and Espeland Mark A

Subjects
Geriatrics, RC952-954.6
Abstract

Abstract Background The efficacy of non-pharmacological intervention approaches such as physical activity, strength, and cognitive training for improving brain health has not been established. Before definitive trials are mounted, important design questions on participation/adherence, training and interventions effects must be answered to more fully inform a full-scale trial. Methods SHARP-P was a single-blinded randomized controlled pilot trial of a 4-month physical activity training intervention (PA) and/or cognitive training intervention (CT) in a 2 × 2 factorial design with a health education control condition in 73 community-dwelling persons, aged 70-85 years, who were at risk for cognitive decline but did not have mild cognitive impairment. Results Intervention attendance rates were higher in the CT and PACT groups: CT: 96%, PA: 76%, PACT: 90% (p=0.004), the interventions produced marked changes in cognitive and physical performance measures (p≤0.05), and retention rates exceeded 90%. There were no statistically significant differences in 4-month changes in composite scores of cognitive, executive, and episodic memory function among arms. Four-month improvements in the composite measure increased with age among participants assigned to physical activity training but decreased with age for other participants (intervention*age interaction p = 0.01). Depending on the choice of outcome, two-armed full-scale trials may require fewer than 1,000 participants (continuous outcome) or 2,000 participants (categorical outcome). Conclusions Good levels of participation, adherence, and retention appear to be achievable for participants through age 85 years. Care should be taken to ensure that an attention control condition does not attenuate intervention effects. Depending on the choice of outcome measures, the necessary sample sizes to conduct four-year trials appear to be feasible. Trial Registration Clinicaltrials.gov Identifier: NCT00688155

Published
2011
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18. Do preparatory behaviours predict alcohol consumption among UK university students?

Author

Cooke, Richard, Bailey, Olivia, Jennings, Janine, Yuen, Chun, and Gardner, Benjamin

Subjects
ALCOHOL drinking, COLLEGE students, REGRESSION analysis, HABIT
Abstract

Objective: This study explored whether the frequency and habitual nature of engagement in three behaviours that may serve as preparation for alcohol consumption on a night out with friends – that is, contacting friends to arrange a night out, buying alcohol, drinking alone at home before going out – predicted consumption on such nights. Design: Prospective correlational design. Methods: One hundred and twenty UK university students (68 female, 50 male, two non‐binary, mean age = 20.78 years, SD = 1.52) completed a survey comprising intentions, habits, and frequency and habit for the three preparatory behaviours. One week later, a second survey measured the number of nights out with friends on which alcohol was drunk (i.e., drinking frequency) and the number on which four or more alcoholic drinks were consumed (i.e, excessive drinking). Regression models were run to predict drinking frequency and excessive drinking. Results: Drinking frequency was predicted only by frequency of contacting friends (B =.28, SE =.12, p =.02), and habitually drinking alone before going out (B =.20, SE =.09, p =.03). Excessive drinking was only predicted by alcohol consumption habit (B =.67, SE =.23, p =.003). Conclusions: Preceding actions may influence the frequency of alcohol consumption on nights out, independently of intentions and habits relating to alcohol consumption. While interventions to reduce consumption quantity in a single session might focus on disrupting the habits that sustain drinking episodes, efforts to reduce alcohol consumption frequency on nights out might focus on disrupting behaviours that precede alcohol consumption. [ABSTRACT FROM AUTHOR]

Published
2021
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20. Dynapenia and Metabolic Health in Obese and Nonobese Adults Aged 70 Years and Older: The LIFE Study

Author

Aubertin-Leheudre, Mylène, primary, Anton, Stephen, additional, Beavers, Daniel P., additional, Manini, Todd M., additional, Fielding, Roger, additional, Newman, Ann, additional, Church, Tim, additional, Kritchevsky, Stephen B., additional, Conroy, David, additional, McDermott, Mary M., additional, Botoseneanu, Anda, additional, Hauser, Michelle E., additional, Pahor, Marco, additional, Gill, Thomas, additional, Fragoso, Carlos, additional, Guralnik, Jack M., additional, Leeuwenburgh, Christiaan, additional, Caudle, Connie, additional, Crump, Lauren, additional, Holmes, Latonia, additional, Lee, Jocelyn, additional, Lu, Ching-ju, additional, Miller, Michael E., additional, Espeland, Mark A., additional, Ambrosius, Walter T., additional, Applegate, William, additional, Byington, Robert P., additional, Cook, Delilah, additional, Furberg, Curt D., additional, Harvin, Lea N., additional, Henkin, Leora, additional, Hepler, Med John, additional, Hsu, Fang-Chi, additional, Lovato, Laura, additional, Roberson, Wesley, additional, Rushing, Julia, additional, Rushing, Scott, additional, Stowe, Cynthia L., additional, Walkup, Michael P., additional, Hire, Don, additional, Rejeski, W. Jack, additional, Katula, Jeffrey A., additional, Brubaker, Peter H., additional, Mihalko, Shannon L., additional, Jennings, Janine M., additional, Hadley, Evan C., additional, Romashkan, Sergei, additional, Patel, Kushang V., additional, Bonds, Denise, additional, Spring, Bonnie, additional, Hauser, Joshua, additional, Kerwin, Diana, additional, Domanchuk, Kathryn, additional, Graff, Rex, additional, Rego, Alvito, additional, Church, Timothy S., additional, Blair, Steven N., additional, Myers, Valerie H., additional, Monce, Ron, additional, Britt, Nathan E., additional, Harris, Melissa Nauta, additional, McGucken, Ami Parks, additional, Rodarte, Ruben, additional, Millet, Heidi K., additional, Tudor-Locke, Catrine, additional, Butitta, Ben P., additional, Donatto, Sheletta G., additional, Cocreham, Shannon H., additional, King, Abby C., additional, Castro, Cynthia M., additional, Haskell, William L., additional, Stafford, Randall S., additional, Pruitt, Leslie A., additional, Berra, Kathy, additional, Yank, Veronica, additional, Fielding, Roger A., additional, Nelson, Miriam E., additional, Folta, Sara C., additional, Phillips, Edward M., additional, Liu, Christine K., additional, McDavitt, Erica C., additional, Reid, Kieran F., additional, Kirn, Dylan R., additional, Pasha, Evan P., additional, Kim, Won S., additional, Beard, Vince E., additional, Tsiroyannis, Eleni X., additional, Hau, Cynthia, additional, Anton, Stephen D., additional, Nayfield, Susan, additional, Buford, Thomas W., additional, Marsiske, Michael, additional, Sandesara, Bhanuprasad D., additional, Knaggs, Jeffrey D., additional, Lorow, Megan S., additional, Marena, William C., additional, Korytov, Irina, additional, Morris, Holly L., additional, Fitch, Margo, additional, Singletary, Floris F., additional, Causer, Jackie, additional, Radcliff, Katie A., additional, Newman, Anne B., additional, Studenski, Stephanie A., additional, Goodpaster, Bret H., additional, Glynn, Nancy W., additional, Lopez, Oscar, additional, Nadkarni, Neelesh K., additional, Williams, Kathy, additional, Newman, Mark A., additional, Grove, George, additional, Bonk, Janet T., additional, Rush, Jennifer, additional, Kost, Piera, additional, Ives, Diane G., additional, Marsh, Anthony P., additional, Brinkley, Tina E., additional, Demons, Jamehl S., additional, Sink, Kaycee M., additional, Kennedy, Kimberly, additional, Shertzer-Skinner, Rachel, additional, Wrights, Abbie, additional, Fries, Rose, additional, Barr, Deborah, additional, Gill, Thomas M., additional, Axtell, Robert S., additional, Kashaf, Susan S., additional, de Rekeneire, Nathalie, additional, McGloin, Joanne M., additional, Wu, Karen C., additional, Shepard, Denise M., additional, Fennelly, Barbara, additional, Iannone, Lynne P., additional, Mautner, Raeleen, additional, Barnett, Theresa Sweeney, additional, Halpin, Sean N., additional, Brennan, Matthew J., additional, Bugaj, Julie A., additional, Zenoni, Maria A., additional, Mignosa, Bridget M., additional, Williamson, Jeff, additional, Hendrie, Hugh C., additional, Rapp, Stephen R., additional, Verghese, Joe, additional, Woolard, Nancy, additional, Espeland, Mark, additional, Jennings, Janine, additional, Wilson, Valerie K., additional, Pepine, Carl J., additional, Ariet, Mario, additional, Handberg, Eileen, additional, Deluca, Daniel, additional, Hill, James, additional, Szady, Anita, additional, Chupp, Geoffrey L., additional, Flynn, Gail M., additional, Hankinson, John L., additional, Vaz Fragoso, Carlos A., additional, Groessl, Erik J., additional, and Kaplan, Robert M., additional

Published
2017
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21. Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults

Author

Wanigatunga, Amal A., primary, Manini, Todd M., additional, Cook, Delilah R., additional, Katula, Jeffrey, additional, Fielding, Roger A., additional, Kramer, Arthur F., additional, Verghese, Joe, additional, Rapp, Stephen R., additional, Sink, Kaycee M., additional, King, Abby C., additional, Buford, Thomas W., additional, Anton, Steve, additional, Nadkarni, Neelesh, additional, Jennings, Janine M., additional, Reid, Kieran, additional, Espeland, Mark A., additional, Gill, Thomas M., additional, Pahor, Marco, additional, and Nocera, Joe R., additional

Published
2018
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22. Predictors of Change in Physical Function in Older Adults in Response to Long-Term, Structured Physical Activity: The LIFE Study

Author

Layne, Andrew S., primary, Hsu, Fang-Chi, additional, Blair, Steven N., additional, Chen, Shyh-Huei, additional, Dungan, Jennifer, additional, Fielding, Roger A., additional, Glynn, Nancy W., additional, Hajduk, Alexandra M., additional, King, Abby C., additional, Manini, Todd M., additional, Marsh, Anthony P., additional, Pahor, Marco, additional, Pellegrini, Christine A., additional, Buford, Thomas W., additional, Guralnik, Jack M., additional, Leeuwenburgh, Christiaan, additional, Caudle, Connie, additional, Crump, Lauren, additional, Holmes, Latonia, additional, Lee, Jocelyn, additional, Lu, Ching-ju, additional, Miller, Michael E., additional, Espeland, Mark A., additional, Ambrosius, Walter T., additional, Applegate, William, additional, Beavers, Daniel P., additional, Byington, Robert P., additional, Cook, Delilah, additional, Furberg, Curt D., additional, Harvin, Lea N., additional, Henkin, Leora, additional, Hepler, John, additional, Lovato, Laura, additional, Roberson, Wesley, additional, Rushing, Julia, additional, Rushing, Scott, additional, Stowe, Cynthia L., additional, Walkup, Michael P., additional, Hire, Don, additional, Rejeski, W. Jack, additional, Katula, Jeffrey A., additional, Brubaker, Peter H., additional, Mihalko, Shannon L., additional, Jennings, Janine M., additional, Hadley, Evan C., additional, Romashkan, Sergei, additional, Patel, Kushang V., additional, Bonds, Denise, additional, McDermott, Mary M., additional, Spring, Bonnie, additional, Hauser, Joshua, additional, Kerwin, Diana, additional, Domanchuk, Kathryn, additional, Graff, Rex, additional, Rego, Alvito, additional, Church, Timothy S., additional, Myers, Valerie H., additional, Monce, Ron, additional, Britt, Nathan E., additional, Harris, Melissa Nauta, additional, McGucken, Ami Parks, additional, Rodarte, Ruben, additional, Millet, Heidi K., additional, Tudor-Locke, Catrine, additional, Butitta, Ben P., additional, Donatto, Sheletta G., additional, Cocreham, Shannon H., additional, Castro, Cynthia M., additional, Haskell, William L., additional, Stafford, Randall S., additional, Pruitt, Leslie A., additional, Berra, Kathy, additional, Yank, Veronica, additional, Nelson, Miriam E., additional, Folta, Sara C., additional, Phillips, Edward M., additional, Liu, Christine K., additional, McDavitt, Erica C., additional, Reid, Kieran F., additional, Kim, Won S., additional, Beard, Vince E., additional, Anton, Stephen D., additional, Nayfield, Susan, additional, Marsiske, Michael, additional, Sandesara, Bhanuprasad D., additional, Knaggs, Jeffrey D., additional, Lorow, Megan S., additional, Marena, William C., additional, Korytov, Irina, additional, Morris, Holly L., additional, Fitch, Margo, additional, Singletary, Floris F., additional, Causer, Jackie, additional, Radcliff, Katie A., additional, Newman, Anne B., additional, Studenski, Stephanie A., additional, Goodpaster, Bret H., additional, Lopez, Oscar, additional, Nadkarni, Neelesh K., additional, Williams, Kathy, additional, Newman, Mark A., additional, Grove, George, additional, Bonk, Janet T., additional, Rush, Jennifer, additional, Kost, Piera, additional, Ives, Diane G., additional, Kritchevsky, Stephen B., additional, Brinkley, Tina E., additional, Demons, Jamehl S., additional, Sink, Kaycee M., additional, Kennedy, Kimberly, additional, Shertzer-Skinner, Rachel, additional, Wrights, Abbie, additional, Fries, Rose, additional, Barr, Deborah, additional, Gill, Thomas M., additional, Axtell, Robert S., additional, Kashaf, Susan S., additional, de Rekeneire, Nathalie, additional, McGloin, Joanne M., additional, Wu, Karen C., additional, Shepard, Denise M., additional, Fennelly, Barbara, additional, Iannone, Lynne P., additional, Mautner, Raeleen, additional, Barnett, Theresa Sweeney, additional, Halpin, Sean N., additional, Brennan, Matthew J., additional, Bugaj, Julie A., additional, Zenoni, Maria A., additional, Mignosa, Bridget M., additional, Williamson, Jeff, additional, Hendrie, Hugh C., additional, Rapp, Stephen R., additional, Verghese, Joe, additional, Woolard, Nancy, additional, Espeland, Mark, additional, Jennings, Janine, additional, Pepine, Carl J., additional, Ariet, Mario, additional, Handberg, Eileen, additional, Deluca, Daniel, additional, Hill, James, additional, Szady, Anita, additional, Chupp, Geoffrey L., additional, Flynn, Gail M., additional, Hankinson, John L., additional, Vaz Fragoso, Carlos A., additional, Groessl, Erik J., additional, and Kaplan, Robert M., additional

Published
2017
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25. The LIFE Cognition Study: design and baseline characteristics

Author

Sink,Kaycee M, Espeland,Mark A, Rushing,Julia, Castro,Cynthia M, Church,Timothy S, Cohen,Ronald, Gill,Thomas M, Henkin,Leora, Jennings,Janine M, Kerwin,Diana R, Manini,Todd M, Myers,Valerie, Pahor,Marco, Ried,Kieran F, Woolard,Nancy, Rapp,Stephen R, Williamson,Jeff D, Sink,Kaycee M, Espeland,Mark A, Rushing,Julia, Castro,Cynthia M, Church,Timothy S, Cohen,Ronald, Gill,Thomas M, Henkin,Leora, Jennings,Janine M, Kerwin,Diana R, Manini,Todd M, Myers,Valerie, Pahor,Marco, Ried,Kieran F, Woolard,Nancy, Rapp,Stephen R, and Williamson,Jeff D

Abstract

Kaycee M Sink,1 Mark A Espeland,2 Julia Rushing,2 Cynthia M Castro,3 Timothy S Church,4 Ronald Cohen,5 Thomas M Gill,6 Leora Henkin,2 Janine M Jennings,7 Diana R Kerwin,8 Todd M Manini,5 Valerie Myers,9 Marco Pahor,5 Kieran F Reid,10 Nancy Woolard,1 Stephen R Rapp,11 Jeff D Williamson1 On behalf of LIFE Investigators 1Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, NC, USA; 2Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA; 3Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA, USA; 4Pennington Biomedical, Louisiana State University, Baton Rouge, LA, USA; 5Institute on Aging and Department of Aging and Geriatric Research, University of Florida, Gainesville, FL, USA; 6Yale School of Medicine, Department of Internal Medicine, New Haven, CT, USA; 7Department of Psychology, Wake Forest University, Winston-Salem, NC, USA; 8Texas Alzheimer’s and Memory Disorders, Texas Health Presbyterian Hospital Dallas, TX, USA; 9Klein Buendel, Inc., Golden, CO, USA; 10Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA; 11Department of Psychiatry and Behavioral Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA Abstract: Observational studies have shown beneficial relationships between exercise and cognitive function. Some clinical trials have also demonstrated improvements in cognitive function in response to moderate–high intensity aerobic exercise; however, these have been limited by relatively small sample sizes and short durations. The Lifestyle Interventions and Independence for Elders (LIFE) Study is the largest and longest randomized controlled clinical trial of physical activity with cognitive outcomes, in older sedentary adults at

Published
2014

28. The LIFE Cognition Study: design and baseline characteristics

Author

Sink, Kaycee, primary, Williamson, Jeff, additional, Espeland, Mark, additional, Rushing, Julia, additional, Castro, Cynthia, additional, Church, Timothy, additional, Cohen, Ronald, additional, Gill, Thomas, additional, Henkin, Leora, additional, Jennings, Janine, additional, Kerwin, Diana, additional, Manini, Todd, additional, Pahor, Marco, additional, Ried, Kieran, additional, Woolard, Nancy, additional, Rapp, Stephen, additional, and Myers, Valerie, additional

Published
2014
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32. Repetition-lag memory training is feasible in patients with chronic stroke, including those with memory problems.

Author

Stamenova, Vessela, Jennings, Janine M., Cook, Shaun P., Gao, Fuqiang, Walker, Lisa A. S., Smith, Andra M., and Davidson, Patrick S. R.

Subjects
*STROKE treatment, *CHRONIC diseases, *MEDICAL care, *MEMORY, *PATIENTS, *REHABILITATION, *RESEARCH funding, *PILOT projects, *CONTROL groups, *DATA analysis software, *DESCRIPTIVE statistics
Abstract

Primary objective: Repetition-lag memory training was developed to increase individuals' use of recollection as opposed to familiarity in recognition memory. The goals of this study were to examine the feasibility of repetition-lag training in patients with chronic stroke and to explore whether the training might show suggestions of transfer to non-trained tasks. Research design: Quasi-experimental. Methods and procedures: Patients (n = 17) took part in six repetition-lag training sessions and their gains on the training and non-trained tasks were compared to those of age-matched healthy controls (n = 30). Main outcomes and results: All but two patients completed the training, indicating that the method is feasible with a wide range of patients with stroke. The amount patients gained on the training task was similar to that of healthy controls (that is, the Group x Time interactions were by-and-large not significant), suggesting that patients with stroke might benefit to the same degree as healthy adults from this training. Both groups showed some indication of transfer to the non-trained backward digit span task and visuospatial memory. Conclusions: These findings show that repetition-lag memory training is a possible approach with patients with stroke to enhance recollection. Further research on the method's efficacy and effectiveness is warranted. [ABSTRACT FROM AUTHOR]

Published
2017
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33. Intraindividual Variability in Domain-Specific Cognition and Risk of Mild Cognitive Impairment and Dementia

Author

Vaughan, Leslie, primary, Leng, Iris, additional, Dagenbach, Dale, additional, Resnick, Susan M., additional, Rapp, Stephen R., additional, Jennings, Janine M., additional, Brunner, Robert L., additional, Simpson, Sean L., additional, Beavers, Daniel P., additional, Coker, Laura H., additional, Gaussoin, Sarah A., additional, Sink, Kaycee M., additional, and Espeland, Mark A., additional

Published
2013
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42. Direct Effects of Smoking Scale

Author

Kleykamp, Bethea A., primary, Jennings, Janine M., additional, Sams, Cynthia, additional, Weaver, Michael F., additional, and Eissenberg, Thomas, additional

Published
2008
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