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14. Additional file 1 of Associations of reproductive factors with incidence of myocardial infarction and ischemic stroke in postmenopausal women: a cohort study

Author

Jeong, Su-Min, Yoo, Jung Eun, Jeon, Keun Hye, Han, Kyungdo, Lee, Heesun, Lee, Dong-Yun, and Shin, Dong Wook

Abstract

Additional file 1: Supplementary Tables. Table S1. A summary of previous studies (selected) on the relationship between reproductive factors and cardiovascular disease incidence. Table S2. Information on missing data. Table S3. Hazard ratios and 95% confidence intervals of myocardial infarction, ischemic stroke, and cardiovascular disease according to reproductive factors (age at menarche, age at menopause, and reproductive span) without lag periods. Table S4. Hazard ratios and 95% confidence intervals of myocardial infarction, ischemic stroke, and cardiovascular disease according to reproductive factors (age at menarche, age at menopause, and reproductive span) adjustment for confounders based on directed acyclic graph. Table S5. Age at menarche in combination with age at menopause and reproductive span and the risk of cardiovascular events. Table S6. Hazard ratios and 95% confidence intervals of cardiovascular disease by reproductive factors according to age group.

Published
2023
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15. Additional file 4 of Associations of reproductive factors with incidence of myocardial infarction and ischemic stroke in postmenopausal women: a cohort study

Author

Jeong, Su-Min, Yoo, Jung Eun, Jeon, Keun Hye, Han, Kyungdo, Lee, Heesun, Lee, Dong-Yun, and Shin, Dong Wook

Abstract

Additional file 4: Fig. S3. Directed acyclic graph illustrating the assumptions about the causal relationship between age at menopause and cardiovascular disease. Red circles indicate confounders, blue circles represent mediators/colliders. The grey circle refers to an unmeasured variable. BMI, body mass index; HRT, hormone replacement therapy; CVD, cardiovascular disease.

Published
2023
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16. Additional file 3 of Associations of reproductive factors with incidence of myocardial infarction and ischemic stroke in postmenopausal women: a cohort study

Author

Jeong, Su-Min, Yoo, Jung Eun, Jeon, Keun Hye, Han, Kyungdo, Lee, Heesun, Lee, Dong-Yun, and Shin, Dong Wook

Abstract

Additional file 3: Fig. S2. Directed acyclic graph illustrating the assumptions about the causal relationship between age at menarche and cardiovascular disease. Red circles indicate confounders, blue circles represent mediators/colliders. The grey circle refers to an unmeasured variable. BMI, body mass index; HRT, hormone replacement therapy; CVD, cardiovascular disease

Published
2023
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19. The Association between the Use of Dietary Supplement and Psychological Status of Cancer Survivors in Korea: A Cross-Sectional Study

Author

Lee, Han Rim, Song, Yun-Mi, Jeon, Keun Hye, and Cho, In Young

Subjects
medicine.medical_specialty, Cross-sectional study, Health Behavior, Anxiety, Hospital Anxiety and Depression Scale, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Cancer Survivors, Internal medicine, medicine, 030212 general & internal medicine, Family history, Stomach cancer, Cancer survivor, Depression, business.industry, Cancer, medicine.disease, humanities, 030220 oncology & carcinogenesis, Dietary Supplements, Original Article, medicine.symptom, Family Practice, business
Abstract

Background: Dietary supplements (DS) use is known to be common among cancer survivors. However, detailed information on the factors influencing DS use seems insufficient, including cancer-related and psychological factors.Methods: Study subjects were 1,852 Korean adult cancer survivors recruited from cancer survivor clinic of two university-affiliated hospitals. Data were collected retrospectively through review of medical records and self-administered questionnaires. Psychological factors were assessed using Hospital Anxiety and Depression Scale (HADS) and Fear of Cancer Recurrence Inventory-Short Form. Factors associated the DS use were evaluated by multiple logistic regression analysis after adjusting for covariates.Results: The prevalence of long-term DS use was 15.7% in overall (17.5% in female and 11.6% in male). Female survivors were 3.14 times (95% confidence interval [CI], 1.89–5.22) more likely to use DS than male. In male cancer survivors, ever-smoking and previous radiotherapy were positively associated with DS use. In females, breast cancer survivors were 0.32 times less likely to use DS compared with stomach cancer survivors, and survivors with family history of cancer were 1.39 times more likely to use DS than those without. After adjusting for sociodemographic, clinical, and lifestyle factors, survivors with anxiety (HADS ≥8) used DS 1.38 times (95% CI, 1.01–1.91) more frequently, compared with those without anxiety.Conclusion: Diverse factors such as female sex, cancer treatment modality, smoking history, family history and anxiety status were associated with DS use in Korean cancer survivors. Targeted strategies with consideration of these factors are needed for counseling DS use for cancer survivors.

Published
2021

21. Association Between Changes in Alcohol Consumption and Cancer Risk

Author

Yoo, Jung Eun, primary, Han, Kyungdo, additional, Shin, Dong Wook, additional, Kim, Dahye, additional, Kim, Bong-seong, additional, Chun, Sohyun, additional, Jeon, Keun Hye, additional, Jung, Wonyoung, additional, Park, Jinsung, additional, Park, Jin Ho, additional, Choi, Kui Son, additional, and Kim, Joo Sung, additional

Published
2022
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37. Golgi Outpost Synthesis Impaired by Toxic Polyglutamine Proteins Contributes to Dendritic Pathology in Neurons

Author

Chung, Chang Geon, primary, Kwon, Min Jee, additional, Jeon, Keun Hye, additional, Hyeon, Do Young, additional, Han, Myeong Hoon, additional, Park, Jeong Hyang, additional, Cha, In Jun, additional, Cho, Jae Ho, additional, Kim, Kunhyung, additional, Rho, Sangchul, additional, Kim, Gyu Ree, additional, Jeong, Hyobin, additional, Lee, Jae Won, additional, Kim, TaeSoo, additional, Kim, Keetae, additional, Kim, Kwang Pyo, additional, Ehlers, Michael D., additional, Hwang, Daehee, additional, and Lee, Sung Bae, additional

Published
2017
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39. Personalized 5-Year Prostate Cancer Risk Prediction Model in Korea Based on Nationwide Representative Data.

Author

Yeo, Yohwan, Shin, Dong Wook, Lee, Jungkwon, Han, Kyungdo, Park, Sang Hyun, Jeon, Keun Hye, Shin, Jungeun, Shin, Aesun, and Park, Jinsung

Subjects
PROPORTIONAL hazards models, PROSTATE cancer, DISEASE risk factors, PREDICTION models, TYPE 2 diabetes, ANDROGEN receptors, NATIONAL health insurance
Abstract

Prostate cancer is the fourth most common cause of cancer in men in Korea, and there has been a rapid increase in cases. In the present study, we constructed a risk prediction model for prostate cancer using representative data from Korea. Participants who completed health examinations in 2009, based on the Korean National Health Insurance database, were eligible for the present study. The crude and adjusted risks were explored with backward selection using the Cox proportional hazards model to identify possible risk variables. Risk scores were assigned based on the adjusted hazard ratios, and the standardized points for each risk factor were proportional to the β-coefficient. Model discrimination was assessed using the concordance statistic (c-statistic), and calibration ability was assessed by plotting the mean predicted probability against the mean observed probability of prostate cancer. Among the candidate predictors, age, smoking intensity, body mass index, regular exercise, presence of type 2 diabetes mellitus, and hypertension were included. Our risk prediction model showed good discrimination (c-statistic: 0.826, 95% confidence interval: 0.821–0.832). The relationship between model predictions and actual prostate cancer development showed good correlation in the calibration plot. Our prediction model for individualized prostate cancer risk in Korean men showed good performance. Using easily accessible and modifiable risk factors, this model can help individuals make decisions regarding prostate cancer screening. [ABSTRACT FROM AUTHOR]

Published
2022
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40. Associations between Alcohol Consumption Patterns and Risk of Multiple Myeloma: A Nationwide Cohort Study in South Korea.

Author

Jeon KH, Jeong SM, Shin DW, Han K, Kim D, Yoo JE, and Choi T

Subjects
Alcohol Drinking adverse effects, Alcohol Drinking epidemiology, Cohort Studies, Female, Humans, Male, Republic of Korea epidemiology, Risk Factors, Multiple Myeloma epidemiology, Multiple Myeloma etiology
Abstract

Background: Among the potential modifiable risk factors, the association between alcohol consumption and the risk of multiple myeloma remains controversial. We investigated the effects of weekly average alcohol consumption and drinking pattern on the risk of multiple myeloma using a nationwide representative database., Methods: We identified 11,737,467 subjects who participated in the Korean National Health Screening Program in 2009 and 2010. Cox regression analyses were performed to calculate the risk of multiple myeloma according to weekly alcohol consumption, drinking frequency, and amount per session., Results: During a mean follow-up period of 6.8 years after a one-year time lag, 6,981 subjects (3,921 men and 3,060 women) were diagnosed with multiple myeloma. Compared with nondrinkers, all drinkers were at a significantly lower risk for multiple myeloma. The risk of multiple myeloma was reduced in a dose-dependent manner: mild drinkers [adjusted HR (aHR), 0.89; 95% confidence interval (CI), 0.84-0.95], moderate drinkers (aHR, 0.83; 95% CI, 0.76-0.91), and heavy drinkers (aHR, 0.76; 95% CI, 0.69-0.85). Furthermore, both drinking frequency and amount per drinking session showed inverse association with the risk of multiple myeloma., Conclusions: Our large population-based study suggested an inverse dose-dependent association between total average alcohol consumption and the risk of multiple myeloma, and drinking frequency and amount per drinking session seemed to not differ in their relative contribution to the risk of multiple myeloma., Impact: On the basis of the unprecedentedly large number of study population analyzed in this study, our study provides solid epidemiologic evidence of alcohol consumption on multiple myeloma risk., (©2021 American Association for Cancer Research.)

Published
2022
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