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3. The 'Korean Wave' and television drama exports, 1995-2005

Author

Jeon, Won Kyung

Subjects
302.23, H Social Sciences (General)
Abstract

Evidently, Korean dramas have become, within just a decade, one of the types of broadcasting content most in demand in many Asian countries, but this popularity, frequently called the Korean Wave, seems to have been obtained rather unexpectedly. This thesis examines how the Korean broadcasting industry succeeded in breaking into neighbouring markets over a relatively short period of time, and whether the Korean government played a certain role in supporting the fast acquisition of Korean dramas of Asian audiences. Through the analysis, using a combined research method, the thesis uncovers how the government’s support policies have not provided meaningful help for drama exports. Rather, the subordinate relationship of Korean broadcasters to the government and the relatively early marketisation of the Korean broadcasting industry have more efficiently stimulated Korean dramas’ entrance into neighbouring broadcasting markets.

Published
2013

5. Mumefural Improves Recognition Memory and Alters ERK-CREB-BDNF Signaling in a Mouse Model of Chronic Cerebral Hypoperfusion.

Author

Kim, Min-Soo, Kim, Bu-Yeo, Kim, Jung Im, Lee, Joungbok, and Jeon, Won Kyung

Abstract

Cognitive impairment resulting from chronic cerebral hypoperfusion (CCH) is known as vascular dementia (VaD) and is associated with cerebral atrophy and cholinergic deficiencies. Mumefural (MF), a bioactive compound found in a heated fruit of Prunus mume Sieb. et Zucc, was recently found to improve cognitive impairment in a rat CCH model. However, additional evidence is necessary to validate the efficacy of MF administration for treating VaD. Therefore, we evaluated MF effects in a mouse CCH model using unilateral common carotid artery occlusion (UCCAO). Mice were subjected to UCCAO or sham surgery and orally treated with MF daily for 8 weeks. Behavioral tests were used to investigate cognitive function and locomotor activity. Changes in body and brain weights were measured, and levels of hippocampal proteins (brain-derived neurotrophic factor (BDNF), extracellular signal-regulated kinase (ERK), cyclic AMP-response element-binding protein (CREB), and acetylcholinesterase (AChE)) were assessed. Additionally, proteomic analysis was conducted to examine the alterations in protein profiles induced by MF treatment. Our study showed that MF administration significantly improved cognitive deficits. Brain atrophy was attenuated and MF treatment reversed the increase in AChE levels. Furthermore, MF significantly upregulated p-ERK/ERK, p-CREB/CREB, and BDNF levels after UCCAO. Thus, MF treatment ameliorates CCH-induced cognitive impairment by regulating ERK/CREB/BDNF signaling, suggesting that MF is a therapeutic candidate for treating CCH. [ABSTRACT FROM AUTHOR]

Published
2023
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6. Ginkgo biloba L. extract protects against chronic cerebral hypoperfusion by modulating neuroinflammation and the cholinergic system

Author

Kim, Min-Soo, Bang, Ji Hye, Lee, Jun, Han, Jung-Soo, Baik, Tae Gon, and Jeon, Won Kyung

Subjects
Materia medica, Vegetable -- Usage -- Health aspects, Shock -- Development and progression -- Care and treatment, Cholinergic mechanisms -- Health aspects, Ginkgo -- Usage -- Health aspects, Plant extracts -- Usage -- Health aspects, Biological sciences, Health, Science and technology
Abstract

ABSTRACT Background: Cinkgo biloba extract (CBE)--a widely used nutraceutical--is reported to have diverse functions, including positive effects on memory and vasodilatory properties. Although numerous studies have assessed the neuroprotective properties [...]

Published
2016
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22. Combined MS/MS-NMR Annotation Guided Discovery of Iris lactea var. chinensis Seed as a Source of Viral Neuraminidase Inhibitory Polyphenols

Author

Kim, Hyun Woo, primary, Kim, Soo Sung, additional, Kang, Kyo Bin, additional, Ryu, Byeol, additional, Park, Eunjin, additional, Huh, Jungmoo, additional, Jeon, Won Kyung, additional, Chae, Hee-Sung, additional, Oh, Won Keun, additional, Kim, Jinwoong, additional, Sung, Sang Hyun, additional, and Chin, Young-Won, additional

Published
2020
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26. Glia produces endogenous excitotoxin via abnormal metabolism and leads to neuronal damage in Alzheimer's disease

Author

Ryu, Hoon, primary, Shim, Hyun Soo, additional, Choi, Mi Hyun, additional, Ko, Hae Young, additional, Yoon, Mijin, additional, Kim, Jong-Heon, additional, Suk, Kyoungho, additional, Oh, Soo-Jin, additional, Nam, Min-Ho, additional, Im, Hyeonjoo, additional, Hyeon, Seung Jae, additional, Nguyen, Phuong, additional, Lee, Junghee, additional, Lee, Jeongae, additional, Kowall, Neil, additional, and Jeon, Won Kyung, additional

Published
2019
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32. A Study on the System of Collaborative Practice between Korean Traditional Medicine and Western Medicine for Dementia based on a Case Study

Author

Lee Go-Eun, Yang Hyun Duk, Jeon Won Kyung, and Kang Hyung-Won

Subjects
medicine.medical_specialty, Activities of daily living, Traditional medicine, medicine.diagnostic_test, business.industry, medicine.medical_treatment, Alternative medicine, Moxibustion, Neuropsychological test, medicine.disease, Test (assessment), Family medicine, Intervention (counseling), medicine, Acupuncture, Dementia, business
Abstract

Objectives : This report describes the diagnostic and therapeutic procedures of Collaborative Practice between Korean Traditional Medicine and Western Medicine for two dementia patients. Furthermore, through these cases, we suggest a model of collaborative practice between Korean traditional medicine and western medicine for the treatment of dementia. Methods : Two patients suffering from several symptoms related to dementia received collaborative practice between Korean traditional medicine and western medicine. Physicians of deparment which paient first visit interviewed patient and patient's guardians, discussed the symptoms and the status of the patient. Since then, the medical team made a differential diagnosis based on the results of brain imaging, hematology, urine test. and apprehended the status of dementia by the neuropsychological test. Korean traditional physicians examined the physical symptoms and identified the pattern of dementia in Korean traditional medicine. Following this, they decided on the method of acupuncture, moxibustion, cupping and herbal treatment. Western physicians decided on the type of medication after consideration of the patient 's other medical conditions. Every intervention was decided by both Korean traditional physicians and western physicians after discussion. The medical team provided education on dementia and counseled the guardians. They also wrote the paper for using the long-term care insurance for the aged. Results : Two patients showed no improvement on the neuropsychologic and activity of daily living tests. However, the patients' subjective physical symptoms were improved. The collaborative practice between Korean traditional medicine and western medicine improved the patients' and guardians' satisfaction. Conclusions : Through these cases, we propose a model of collaborative practice between Korean traditional medicine and western medicine for dementia categorized diagnosis-test, treatment, prevention, management. More specifically, we supplement qigong and psychotherapy which was inadequate in these cases.

Published
2013

39. <italic>Terminalia chebula</italic> extract prevents scopolamine-induced amnesia via cholinergic modulation and anti-oxidative effects in mice.

Author

Kim, Min-Soo, Lee, Dong Young, Lee, Jun, Kim, Hyun Woo, Sung, Sang Hyun, Han, Jung-Soo, and Jeon, Won Kyung

Subjects
ACETYLCHOLINE, ACETYLCHOLINESTERASE, ACETYLTRANSFERASES, REACTIVE oxygen species, AMNESIA, ANIMAL experimentation, COGNITION, HIPPOCAMPUS (Brain), INTRAPERITONEAL injections, LEARNING, MEDICINAL plants, MEMORY, MEMORY disorders, MICE, NEURAL transmission, NITRIC oxide, ORAL drug administration, SCOPOLAMINE, MALONDIALDEHYDE, PLANT extracts, OXIDATIVE stress, PHARMACODYNAMICS
Abstract

Background: Terminalia chebula Retz. (Combretaceae) is a traditional herbal medicine that is widely used in the treatment of diabetes, immunodeficiency diseases, and stomach ulcer in Asia. However, the anti-amnesic effect of T. chebula has not yet been investigated. The present study was designed to determine whether T. chebula extract (TCE) alleviates amnesia induced by scopolamine in mice. We also investigated possible mechanisms associated with cholinergic system and anti-oxidant effects. Methods: TCE (100 or 200 mg/kg) was orally administered to mice for fourteen days (days 1–14), and scopolamine was intraperitoneally injected to induce memory impairment for seven days (days 8–14). Learning and memory status were evaluated using the Morris water maze. Hippocampal levels of acetylcholine (ACh), acetylcholinesterase (AChE) and choline acetyltransferase (ChAT) were measured ex vivo. Levels of reactive oxygen species (ROS), nitric oxide (NO), and malondialdehyde (MDA) in the hippocampus were also examined. Results: In the Morris water maze task, TCE treatment reversed scopolamine-induced learning and memory deficits in acquisition and retention. TCE reduced hippocampal AChE activities and increased ChAT and ACh levels in the scopolamine-induced model. Moreover, TCE treatment suppressed scopolamine-induced oxidative damage by ameliorating the increased levels of ROS, NO, and MDA. Conclusion: These findings suggest that TCE exerts potent anti-amnesic effects via cholinergic modulation and anti-oxidant activity, thus providing evidence for its potential as a cognitive enhancer for amnesia. [ABSTRACT FROM AUTHOR]

Published
2018
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42. Recurrence-associated pathways in hepatitis B virus-positive hepatocellular carcinoma

Author

Kim, Bu-Yeo, primary, Choi, Dong Wook, additional, Woo, Seon Rang, additional, Park, Eun-Ran, additional, Lee, Je-Geun, additional, Kim, Su-Hyeon, additional, Koo, Imhoi, additional, Park, Sun-Hoo, additional, Han, Chul Ju, additional, Kim, Sang Bum, additional, Yeom, Young Il, additional, Yang, Suk-Jin, additional, Yu, Ami, additional, Lee, Jae Won, additional, Jang, Ja June, additional, Cho, Myung-Haing, additional, Jeon, Won Kyung, additional, Park, Young Nyun, additional, Suh, Kyung-Suk, additional, and Lee, Kee-Ho, additional

Published
2015
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