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429 results on '"Jeong, S-Y"'

1. Value of 68Ga-PSMA PET/CT compared to mpMRI for primary tumor characterization based on radical prostatectomy histopathology

Author

Lim, J.S., primary, Yun, O.J., additional, Kang, J.H., additional, Lee, S.H., additional, Kang, J-K., additional, Jo, I., additional, Chung, J-W., additional, Ha, Y-S., additional, Choi, S.H., additional, Lee, J.N., additional, Kim, B.S., additional, Jeong, S-Y., additional, Kim, H.T., additional, Kim, T-H., additional, Yoo, E.S., additional, and Kwon, T.G., additional

Published
2024
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13. Minimally invasive surgical staging for early stage ovarian cancer: A long-term follow up

Author

Gallotta, V., Jeong, S. Y., Conte, C., Trozzi, R., Cappuccio, S., Moroni, R., Ferrandina, G., Scambia, G., Kim, T. -J., Fagotti, A., Gallotta V., Conte C., Trozzi R., Ferrandina G. (ORCID:0000-0003-4672-4197), Scambia G. (ORCID:0000-0003-2758-1063), Fagotti A. (ORCID:0000-0001-5579-335X), Gallotta, V., Jeong, S. Y., Conte, C., Trozzi, R., Cappuccio, S., Moroni, R., Ferrandina, G., Scambia, G., Kim, T. -J., Fagotti, A., Gallotta V., Conte C., Trozzi R., Ferrandina G. (ORCID:0000-0003-4672-4197), Scambia G. (ORCID:0000-0003-2758-1063), and Fagotti A. (ORCID:0000-0001-5579-335X)

Abstract

Introduction: The standard treatment for epithelial early stage ovarian cancer (eEOC) includes laparotomic surgical staging, according to ESGO-ESMO guidelines. In the last decade, many investigators have assessed the safety and feasibility of minimally invasive surgery (MIS) staging in properly selected patients. However, survival data related to different surgical approaches (open versus MIS) are extremely limited. The aim of this study is to analyze the long-term oncological outcomes in eEOC patients treated with MIS. Materials and methods: This is a multicenter observational retrospective study conducted in two tertiary oncological centers. We selected all consecutive women who underwent a laparoscopic or robotic staging for eEOC. Results: From January 2008 to December 2016, 254 eEOC patients underwent a MIS staging (188 laparoscopic staging and 66 robotic staging). Overall, 18.1% of patients were upstaged due to pathological findings. A total of 203 (79.9%) patients received platinum-based adjuvant chemotherapy. After a median follow-up of 61 months (range 13–118), 39 (15.3%) patients experienced recurrence. The 5-years progression free survival (PFS) and overall survival rates were 84.0% and 93.8%, respectively. In the univariate analysis, favorable variables influencing PFS were young age (≤45 years), non-serous histotype, tumor grade 1-2, and FIGO stage IA/IB. In the multivariate analysis, only grade 3 was shown to keep its negative independent prognostic value (HR = 3.47; p = 0.004), whereas FIGO stage ≥ IC showed a trend toward significance (HR = 1.75; p = 0.099). Conclusion: This retrospective study represents the longest follow-up of eEOC patients managed by MIS. The MIS is a valuable therapeutic option in appropriately selected patients, although a randomized controlled trial is needed.

Published
2021

21. Poster display II clinical general

Author

Gurgenyan, S. V. Svetlana, Vatinyan, S. K. H., Nikogosyan, K. G., Edilyan, L. B., Chobanyan, B. G., Lacourcière, Y., Marcel Dumont, M., Lefebvre, J., Poirier, L., Côté, C., Peix, A. Amalia, Alonso, O., Chae, I. H., Chung, J. K., Gutierrez, C., Kropp, J., Onsel, C., Silvasi, I., Llerena, L., Padhy, A. K., Garcia-Barreto, D., Trapaga, A., Asen, L., Infante, O., Ponce, F., Cabrera, L. O., Valiente, J., Tornes, F., Guerrero, I., Zayas, R., ones, M. A. Quin, Castro, J., Fayad, Y., Carrillo, R., Paz, A. De, Mehlsen, J. Jesper, Hædersdal, C., Daou, D. Doumit, Benada, A., Lebtahi, R., Idy-Peretti, I., Guludec, D. Le, Coaguila, C., Vilain, D., Leenhardt, A., Heinicke, N. Norbert, Benesch, B., Kaiser, T., Seegmüller, M., Schönberger, J., Eilles, C., Riegger, G. A. J., Holmer, S., Luchner, A., Kouris, N. T. Nikos, Kontogianni, D. D., Goranitou, G. S., Sifaki, M. D., Kalkandi, E. M., Grassos, H. E., Papoulia, E., Babalis, D. K., Moralidis, E. Efstratios, Spyridonidis, T., Arsos, G., Karakatsanis, K., Karatzas, N., Parameswaran, R. V. Ramanathapuram, Sundaram, P. S. Palaniswamy Shanmuga, Padma, S., Haridas, K. K., Zachariah, M., Kumar, S., Feola, M. Mauro, Leonardi, G., Peano, S., Bianchi, A., Dutto, P., Guala, E., Biggi, A., Uslenghi, E., Filardi, P. Pasquale Perrone, Pace, L., Dellegrottaglie, S., Corrado, L., Cafiero, M., Camerino, R., Maglione, A., Polimeno, M., Zarrilli, A., Chiariello, M., Giorgetti, A. Assuero, Gimelli, A., Marini, C., Schluter, M., Kusch, A., D’Aragona, I., Marzullo, P., Gimelli, A. Alessia, Stanislao, M., Zanco, P., Inglese, E., Bertelli, P., Valle, G., Tassone, F., Pepino, R., Francini, A., Garrone, O., Occelli, M., Merlano, M., Florimonte, L. Luigia, Pagani, L., Piatti, L., Butti, I., Maffioli, L. S., Casorelli, E., Dottore, F. Del, Gentili, G., Agostini, M., Pieri, P. L. Pierluigi, Milan, E., Giubbini, R. Raffaele, Mazzanti, M. Marco, Serenelli, M., Perna, G. P., Ferro, A., Duilio, C., Santomauro, M., Salvatore, M., Cuocolo, A. Alberto, Bertagna, F., Bosio, G., Terzi, A., Paghera, B., Kaneta, T. Tomohiro, Otani, H., Hakamatsuka, T., Fukuda, H., Nakazato, R. Ryo, Moroi, M., Kunimasa, T., Furuhashi, T., Sugi, K., Yasuhi, W. Watanabe, Akihiro, S., Yukawa, A., Ryu, K., Kimio, T., Yasuhiko, T., Nariaki, E., Yasunori, W., Akashi, Y. J. Yoshihiro, Musha, H., Kida, K., Itoh, K., Inoue, K., Kawasaki, K., Hashimoto, N., Nakazawa, K., Miyake, F., Fukuzawa, S. Shigeru, Ozawa, S., Inagaki, M., Sugioka, J., Okino, S., Matsuo, S. Shinro, Matsumoto, T., Nakae, I., Masuda, D., Horie, M., Mori, Y. Yoshitomo, Takahashi, K., Masai, M., Kawasaki, D., Kanemori, T., Okuda, S., Tanabe, K., Ohyanagi, M., Takahashi, K. Keiko, Masai, M., Mori, Y., Tanabe, K., OKuda, S., Toyama, T. Takuji, Hoshizaki, H., Seki, R., Isobe, N., Kawaguchi, R., Oshima, S., Taniguchi, K., Nakagawa, K. Keiichi, Sekine, T., Yamazaki, M., Komuro, I., Kim, K. M. Kyeong Min, Teramoto, N., Jino, H., Ohta, Y., Watabe, H., Hayashi, T., Iida, H., Nishimura, T. Tohru, Nagae, A., Morishima, K., Shigeyama, T., Shimoyama, K., Yoshino, H., Kawai, Y. Yuko, Jeong, S. Y., Lee, J. Jae-Tae, Seo, J. H., Bae, J. H., Ahn, B. C., Chae, S. C., Lee, K. B., Cho, I. Ihnho, Chun, K., Won, K., Lee, H., Hong, G., Park, J., Shin, D., Kim, Y., Shim, B., Pavlovic, J. Maksimovic, Peovska, I. Irena, Vavlukis, M., Gorceva, D. Pop, Majstorov, V., Alexanderson, E. Erick, Meave, A., Ricalde, A., Teresinska, A. Anna, Sliwinski, M., Konieczna, S., Szymanska, M., Hendzel, P., Juraszynski, Z., Debski, A., Szumilak, B., Kostkiewicz, M. Magdalena, Wilkolek, P., Pasowicz, M., Klimeczek, P., Pieniazek, P., Przewlocki, T., Pieculewicz, M., Tracz, W., Szot, W., Trebacz, J., Zmudka, K., Podolec, P., Dziuk, M. Miroslaw, Kazmierczak, A., Kot, E., Pietrzykowski, J., Cholewa, M., Coutinho, M. C. Maria Azevedo, Correia, M. J., Cantinho, G., Conceição, I., Bernardes, A., Silva, A., Gaspar, F., Cunha, J. A. Correia da, Lourenço, C. Cândida, Roque, C., Ferrer-Antunes, A., Ferreira, M., Providência, L. A., Lima, J., Abreu, A. Ana, Castillejos, L., Henriksson, I., Oliveira, L., Rosário, L., Geão, A., Pereira, E., Colarinha, P., Romero-Farina, G., Candell-Riera, J., Aguadé-Bruix, S. Santiago, Leon, G. De, Caresia, A. P., Mila-Lopez, M., Garcia-Alonso, C., Pifarre-Montaner, P., Negre-Buso, M., Castell-Conesa, J., Mestre-Fusco, A., Porta-Biosca, F., Aguadé-Bruix, S. Santiago, Muxi, A. Africa, Paredes, P., Ortin, J., Duch, J., Diaz-Infante, E., Fuertes, S., Orus, J., Mont, L. L., Pons, F., Pollack, C., Hellermann, J. P., Namdar, M., Siegrist, P. T. Patrick, Koepfli, P., Bartenstein, N., Schurr, U., Jenni, R., Kaufmann, P. A., Hassad, R. Rim, Hamami, H., Sellem, A., Brahim, H. Ben, Caglar, M. Meltem, Mahmoudian, B., Aytemir, K., Kahraman, S., Arýcý, M., Kabakcý, G., Karabulut, E., Akincioglu, C. Cigdem, Berman, D. S., Nishina, H., Hayes, S. W., Kavanagh, P. B., Friedman, J. D., Slomka, P. J., Germano, G., Entok, E. Emre, Cavusoglu, Y., Vardareli, E., Timuralp, B., Cheetham, A., Naylor, V., Ghiotto, F., McGhie, J., Al-Housni, M. B., Kelion, A. D. Andrew, Hutchings, F., Hinton-Taylor, S., Birkbeck, P., Thatikonda, S., Feldkamp, M., Rosamond, T. Thomas, Raza, M., Panjrath, G. S. Gurusher, Haider, A., Jain, D., Yang, A., Schumacher, R., Reynolds, J., Clark, E., Speiser, D., Schindel, M., Hackney, T., Vacek, J., Jindal, V. Vikas, Dim, U. Uzodinma, Hamburg, L. M., Mouradian, V., Nichols, K. J., Akinboboye, O. O., Snyder, K., Polepalle, D., DePuey, G. Gordon, Khattak, H., Friedman, M., Thompson, L., Thompson, R. C. Randall, McGhie, A. I., Moser, K., O’Keefe, J. H., Fritsch, N., Bateman, T. M., Mut, F., Vidal, I., Rener, A., Nuñez, M., Alvarez, B., and Beretta, M. Mario

Published
2005
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22. Posters display III clinical outcome and PET

Author

Baliño, N. Nestor Perez, Masoli, O., Traverso, S., Grynberg, L., Rappallo, C., Redruello, M., Rosa, D., Cragnolino, D., Meretta, A., Vidal, L., Graf, S., Khorsand, A. Aliasghar, Gyongyosi, M., Karanikas, G., Eidherr, H., Kletter, K., Porenta, G., Glogar, D., Sochor, H., Beheshti, M., Poetzi, C., Wadsak, W., Porenta, G., Maurer, G., Wolfram, J., Winter, O. Olivier De, Velghe, A., Veire, N. Van de, Bondt, P. De, Buyzere, M. De, Wiele, C. Van de, Backer, G. De, Gillebert, T. C., Dierckx, R. A., Sutter, J. De, Bernard, D., Langlois, M., Duarte, P. S. Paulo, Mastrocolla, L. E., Sampaio, C. R. E., Rossi, J. M., Smanio, P. E., Lima, E. V., Oliveira, C. A. R., Pereira, J. C. R., Smanio, P. Paola, Beraldo, P., Rodrigues, F., Thom, A., Yoshinaga, K. Keiichiro, Ukkonen, H., Burwash, I., DeKemp, R., Dafoe, W., Davies, R., Haddad, H., Ruddy, T., DaSilva, J., Beanlands, R., Chow, B., Williams, K., Garrard, L., Szeto, A., Aung, M., Sondergaard, H. Hanne, Bottcher, M., Madsen, M. M., Schmitz, O., Nielsen, T. T., Botker, H. E., Høilund-Carlsen, P. F. Poul F., Johansen, A., Christensen, H. W., Vach, W., Møldrup, M., Haghfelt, T., Johansen, A. Allan, Høilund-Carlsen, P. F., Christensen, H. W., Møldrup, M., Kristensen, J. Jens Hedega, Maeng, M., Mortensen, U. M., Berg, J. S., Rehling, M., Nielsen, T. T., Elsaban, K. Khaled, El-Kady, T., El-Gabaly, M., Yehia, A., El-Sayed, M., Naum, A. Alexandru, Laaksonen, M. S., Tuunanen, H., Oikonen, V., Kemppainen, J., Järvisalo, M. J., Nuutila, P., Knuuti, J., Vanzetto, G. Gerald, Jacon, P., Fagret, D., Machecourt, J., Lindner, O. Oliver, Vogt, J., Kammeier, A., Fricke, E., Wielepp, P., Baller, D., Lamp, B., Holzinger, J., Horstkotte, D., Burchert, W., Nekolla, S. G. Stephan, Souvatzoglou, M., Hausleiter, J., Henke, N., Kruschke, K., Bengel, F., Schwaiger, M., Sundaram, P. S. Palaniswamy Shanmuga, Padma, S., Haridas, K. K., Kumar, S., Zachariah, M., Livschitz, S. Shay, Zornitzki, T., Vered, S., Oettinger, M., Levy, R., Caspi, A., Faraggi, D., Knobler, H., Mats, I., Solodky, A., Ben-Gal, T., Battler, A., Zafrir, N. Nili, Varani, E. Elisabetta, Balducelli, M., Severi, S., Patroncini, A. L., Vecchi, G., Gatti, C., Corbelli, C., Casanova, R., Maresta, A., Cittanti, C. Corrado, Valgimigli, M., Giganti, M., Malagutti, P., Percoco, G., Bagatin, E., Panareo, S., Avigni, N., Ferrari, R., Feggi, L., Filardi, P. Pasquale Perrone, Cuocolo, A., Storto, G., Brevetti, G., Dellegrottaglie, S., Corrado, L., Cafiero, M., Polimeno, M., Zarrilli, A., Chiariello, M., Marcassa, C. Claudio, Campini, R., Calza, P., Giannuzzi, P., Galassi, A. R. Alfredo, Grasso, C., Azzarelli, S., Leotta, E., Moshiri, S., Tamburino, C., Acampa, W., Ferro, A., Petretta, M., Salvatore, M., Cuocolo, A. Alberto, Pieri, P. L. Pierluigi, Berta, R., Moscatelli, G., Buccoliero, F., Inglese, E., Marcassa, C. Claudio, Medolago, G., Imperiale, A., Rimini, M. L. De, Bertagna, F., Sullo, P., Lupo, M., Cappagli, M., Fukuda, H. Hiroshi, Kunimasa, T., Furuhashi, T., Moroi, M., Yasuhi, W. Watanabe, Akihiro, S., Akio, Y., Ryou, K., Kimio, T., Yasunori, W., Yasuhiko, T., Nariaki, E., Watabe, H. Hiroshi, Teramoto, N., Ohta, Y., Kou, Y., Hayashi, T., Iida, H., Bom, H. S. Hee-Seung, Song, H. C., Min, J. J., Heo, Y. J., Seo, J. H., Lee, J. Jae-Tae, Bae, J. H., Jeong, S. Y., Ahn, B. C., Chae, S. C., Lee, K. B., Popiel, M. Malgorzata, Grajek, S., Czepczynski, R., Breborowicz, P., Lesiak, M., Czyz, A., Sawinski, K., Komarnicki, M., Cieslinski, A., Sowinski, J., Ferreira, A. António, Ventosa, A., Gil, V., Calqueiro, J., Lima, S., Aguiar, C., Couto, R., Raposo, L., Seabra-Gomes, R., Vasconcelos, M. Mariana, Martins, E., Faria, T., Oliveira, A., Garcia, M., Pereira, J., Rocha-Gonçalves, F., Lourenço, C. Cândida, Roque, C., Ferrer-Antunes, A., Ferreira, M., Providência, L. A., Lima, J., Medrea, C. Claudia, Bogdan, R., Lazar, A., Mot, S., Capilneanu, R., Kozulin, V. Vickenty, Berkovich, O., Ivashchenko, T., Larionova, V., Esipovich, I., Gordeev, M., Panov, A., Shlyakhto, E., Burova, N., Baranov, D., Timoshin, V., Chuprova, S., Shkolnikova, M., Zaklyazminskaya, E., Poliakov, A., Sazonova, S. Svetlana, Romero-Farina, G., Arenillas, J. F., Candell-Riera, J., Aguadè-Bruix, S. Santiago, Leon, G. De, Molina, C. A., Chacon, P., Montaner, J., Rovira, A., Alvarez-Sabin, J., Namdar, M. Mehdi, Siegrist, P. T., Grathwohl, R., Delaloye, R., Koepfli, P., Wyss, C. A., Kaufmann, P. A., Bartenstein, N., Hellermann, J., Siegrist, P. T. Patrick, Namdar, M., Pollack, C., Schurr, U., Kaufmann, P. A., Zellweger, M. J. Michael, Burger, P. C., Mueller-Brand, J., Pfisterer, M. E., Gordon, L. Leonie, Epps, A., Chiarameda, S., Navare, S. Sachin, Ahlberg, A., Cyr, G., Katten, D., Ausef, A., Heller, G., Darrow, B. Bruce, Thomas, G. S. Gregory, Ip, T. K., Thompson, R. C., Kramer, D. B., Rice, D. L., Thomas, J. J., Miyamoto, M. I., Druz, R. S. Regina, Nichols, K. J., Akinboboye, O. O., Reichek, N., Podrasky, E. Ernest, Tuttle, R. T. Robert, Shaw, L. S. Linda, Hanson, M. W. H. Michael, Borges-Neto, S. Salvador, Lundbye, J. Justin, Werden, S., Kazi, F., Whalen, A., Noble, G. L., O’Sullivan, D., Boden, W. E., Heller, G. V., Ausef, A. Amir, Ahlberg, A. W., Danias, P. G., Papaioannou, G. I., Leka, I. A., Boden, W. E., Heller, G. V., Beretta, M. Mario, Viňas, S., Gonzalez, A., Vidal, I., and Rener, A.

Published
2005
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44. Comparison of five membrane filters to collect bioaerosols for airborne microbiome analysis.

Author

Jeong, S.‐Y. and Kim, T.G.

Subjects
*MEMBRANE filters, *MICROBIOLOGICAL aerosols, *FUNGAL DNA, *POLYVINYLIDENE fluoride, *CELLULOSE esters, *POLYAMIDES, *POLYETHERSULFONE
Abstract

Aims: Recovering DNA of airborne micro‐organisms (AM) from air is a challenging task. We compared five membrane filters for bioaerosol sampling—mixed cellulose ester (MCE), polyethersulfone (PES), polyamide (PA), polytetrafluorethylene (PTFE) and polyvinylidene fluoride (PVDF)—based on their bacterial, fungal and eukaryotic DNA recoveries. Methods and results: Bacterial, fungal and eukaryotic populations were quantified using quantitative PCR. With a bacterial consortium, PTFE exhibited the best recovery efficiency (113%), followed by PA (92%), PES (86%), MCE (48%) and PVDF (1%). When filters were compared with air, PA was used as a control to normalize results from the others. The bacterial, fungal and eukaryotic DNA recovery ratios were markedly greater in PES (9·3, 11·5 and 10·3 respectively) than in the remaining. Eukaryotic MiSeq sequencing revealed that PES recovered a more diverse and considerably richer assemblage (richness ratios, 4·97 vs ≤ 1·16 for PES vs the others). Rank abundance distribution analysis showed that distribution tails were longer (>4 times) in PES, but these did not differ between the remaining and PA. Community comparison showed that PES exhibited a lower variation across trials than the PA, while the remaining did not. Conclusions: PES filter markedly outperformed the other filters in quantitative and qualitative recovery of AM. Significance and Impact of the Study: Our findings demonstrated the importance of filter selection for sampling AM. [ABSTRACT FROM AUTHOR]

Published
2021
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45. Anterior resection syndrome: a randomized clinical trial of a 5-HT3 receptor antagonist (ramosetron) in male patients with rectal cancer.

Author

Ryoo, S.-B., Park, J. W., Lee, D. W., Lee, M. A., Kwon, Y.-H., Kim, M. J., Moon, S. H., Jeong, S.-Y., and Park, K. J.

Subjects
RECTAL cancer, CLINICAL trials, RECTAL surgery, ILEOSTOMY, ONCOLOGIC surgery, CANCER patients, CONSERVATIVE treatment
Abstract

Background: No effective treatment exists for anterior resection syndrome (ARS) following sphincter-saving surgery for rectal cancer. This RCT assessed the safety and efficacy of a 5-HT3 receptor antagonist, ramosetron, for ARS. Methods: A single-centre, randomized, controlled, open-label, parallel group trial was conducted. Male patients with ARS 1 month after rectal cancer surgery or ileostomy reversal were enrolled and randomly assigned (1:1) to 5 µg of ramosetron (Irribow#&174;) daily or conservative treatment for 4 weeks. Low ARS (LARS) score was calculated after randomization and 4 weeks after treatment. The study was designed as a superiority test with a primary endpoint of the proportion of patients with major LARS between the groups. Primary outcome analysis was based on the modified intention-to-treat population. Safety was assessed by monitoring adverse events during the study. Results: A total of 100 patients were randomized to the ramosetron (49 patients) or conservative treatment group (51 patients). Two patients were excluded, and 48 and 50 patients were analysed in the ramosetron and control groups, respectively. The proportion of major LARS after 4 weeks was 58 per cent (28 of 48 patients) in the ramosetron group versus 82 per cent (41 of 50 patients) in the control group, with a difference of 23.7 per cent (95 per cent c.i. 5.58 to 39.98, P=0.011). There were minor adverse events in five patients, which were hard stool, frequent stool or anal pain. These were not different between the two groups. There were no serious adverse events. Conclusion: Ramosetron could be safe and feasible for male patients with ARS. [ABSTRACT FROM AUTHOR]

Published
2021
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49. Predictors of permanent stoma creation in patients with mid or low rectal cancer: results of a multicentre cohort study with preoperative evaluation of anal function.

Author

Kim, S., Kim, M. H., Oh, J. H., Jeong, S.‐Y., Park, K. J., Oh, H.‐K., Kim, D.‐W., and Kang, S.‐B.

Subjects
RECTAL cancer, ILEOSTOMY, ABDOMINOPERINEAL resection, COHORT analysis, CANCER patients
Abstract

Aim: Preoperative factors predictive of permanent stoma creation were investigated in a long‐term follow‐up of patients with mid or low rectal cancer. Method: We included patients who underwent radical resection for mid or low rectal cancer with available data for preoperative anal function measured by manometry and Faecal Incontinence Severity Index questionnaire between January 2005 and December 2015 in three tertiary referral hospitals. A permanent stoma was defined as a stoma present until the patient's last follow‐up visit or death. Preoperative factors that predicted permanent stoma creation were analysed. Results: Over a median follow‐up of 57.4 months (range 12–143 months), a permanent stoma was created in 144/577 (25.0%) patients, including 89 (15.4%) who underwent abdominoperineal resection, one (0.2%) who underwent Hartmann's operation without reversal, 15 (2.6%) with a diverting ileostomy at the time of initial sphincter‐preserving surgery without undergoing stoma reversal, and 39 (6.8%) who underwent permanent ileostomy formation after sphincter‐preserving surgery. Patients with permanent stoma creation had a shorter tumour distance from the anal verge (P < 0.001), larger tumour size (P = 0.020) and higher preoperative Faecal Incontinence Severity Index score (P = 0.020). On multivariable analysis, tumour distance from the anal verge predicted permanent stoma formation (relative risk 0.53 per centimetre increase; 95% confidence interval 0.46–0.60; P < 0.001) but preoperative anal function did not. Conclusion: Tumour distance from the anal verge was the only preoperative determinant of permanent stoma creation in rectal cancer patients. These data may help mid and low rectal cancer patients understand the need for permanent stoma. [ABSTRACT FROM AUTHOR]

Published
2020
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50. Effects of quorum quenching on temporal succession of activated sludge microbial community in a membrane bioreactor.

Author

Jo, S.J., Jeong, S.‐Y., Kwon, H., Lee, S.H., Oh, H.‐S., Yi, T., Park, P.‐K., Lee, C.‐H., and Kim, T.G.

Subjects
*BACTERIAL communities, *BACTERIAL diversity, *COMMUNITY organization, *COMMUNITY change, *FOULING, *MICROBIAL communities
Abstract

Aims: Quorum quenching (QQ) is an attractive strategy for mitigating biofouling in membrane bioreactors (MBRs). However, the effects of QQ on the activated sludge (AS) process have not been adequately evaluated. This study investigated the long‐term effects of QQ on a laboratory‐scale anoxic–oxic MBR, focusing on AS performance and microbial community. Methods and Results: Anoxic–oxic MBRs with and without QQ were operated for 91 days. QQ did not affect COD and TN removal efficiencies over the experimental period, during which its activity remained >90%. QQ reduced floc size by approximately 8% but had no effect on biomass concentration. AS microbial communities were regularly analysed using massively parallel sequencing. AS bacterial communities were temporally dynamic irrespective of QQ presence, for example, a temporal increase in bacterial diversity and a temporal decay of community similarity. QQ counteracted the temporal change in diversity and the temporal distance–community decay. Community comparison revealed that QQ changed the successional trajectory of the AS community at a late period, because it decelerated temporal changes of specific members, such as Thiothrix and Sphingomonadaceae*. Correlation networks revealed that QQ increased network clustering, complexity and density. The combined results suggest that the tighter microbial association by QQ increased the community resistance. Conclusions: QQ can enhance the diversity and stability of the AS community in MBR by counteracting the innate temporal change in community structure. Significance and Impact of the Study: Our findings are useful for the further advancement of QQ‐based strategies in engineered microbial environments. [ABSTRACT FROM AUTHOR]

Published
2020
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