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5 results on '"Jeremy, Mock"'

2. Excision of a sclerosing polycystic adenosis of the deep parotid gland

Author

Erik Moyer, Mohammed Amer Swid, Robert Tuliszewski, James Barrese, Jeremy Mock, and Renee Frank

Subjects
Male, Histology, Adolescent, Cysts, Biopsy, Fine-Needle, Humans, Parotid Gland, Female, General Medicine, Fibrocystic Breast Disease, Salivary Glands, Parotid Neoplasms, Pathology and Forensic Medicine
Abstract

A 15-year-old male presented to the hospital with a 2-month history of a right parotid mass. Magnetic resonance imaging revealed an encapsulated 3.7 cm mass. Fine-needle aspiration suggested a monomorphic adenoma (prior to utilization of the Milan Classification system). Total parotidectomy was performed with dissection and preservation of the facial nerve. Surgical pathology identified the lesion as sclerosing polycystic adenosis (SPA) after examining the histopathological and immunohistochemistry findings. SPA is a rare lesion which leads to inflammatory changes in the salivary gland. The most common site impacted is the parotid gland but also can affect other major or minor salivary glands. The fibrocystic changes are morphologically like the histological developments of sclerosing adenosis of breast tissue. Those changes consist of fibrosis, apocrine metaplasia, and different degrees of proliferation of ducts, acini, and myoepithelial cells. The pathogenesis of SPA is unknown but recent studies suggest that it could be a neoplasm. Treatment with surgical excision is effective and its' recurrence is rare. This case report details the cytomorphology, histology, and immunohistochemical profile of SPA.

Published
2021
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3. A Global Analysis of Light and Charge Yields in Liquid Xenon

Author

Jeremy Mock, B. G. Lenardo, Mani Tripathi, Matthew Szydagis, Kareem Kazkaz, and A. Manalaysay

Subjects
Physics, Nuclear and High Energy Physics, Physics - Instrumentation and Detectors, Photon, Dark matter, Monte Carlo method, FOS: Physical sciences, chemistry.chemical_element, Markov chain Monte Carlo, Instrumentation and Detectors (physics.ins-det), Particle detector, Computational physics, symbols.namesake, Xenon, Nuclear Energy and Engineering, chemistry, Simulated annealing, symbols, Electrical and Electronic Engineering, Astrophysics - Instrumentation and Methods for Astrophysics, Instrumentation and Methods for Astrophysics (astro-ph.IM), Free parameter
Abstract

We present an updated model of light and charge yields from nuclear recoils in liquid xenon with a simultaneously constrained parameter set. A global analysis is performed using measurements of electron and photon yields compiled from all available historical data, as well as measurements of the ratio of the two. These data sweep over energies from 1 - 300 keV and external applied electric fields from 0 - 4060 V/cm. The model is constrained by constructing global cost functions and using a gradient descent minimizer, a simulated annealing algorithm, and a Markov Chain Monte Carlo approach to optimize and find confidence intervals on all free parameters in the model. This analysis contrasts with previous work in that we do not unnecessarily exclude data sets nor impose artificially conservative assumptions, do not use spline functions, and reduce the number of parameters used in NEST v0.98. We report our results and the calculated best-fit charge and light yields. These quantities are crucial to understanding the response of liquid xenon detectors in the energy regime important for rare event searches such as the direct detection of dark matter particles., 9 pages, 11 figures

Published
2015
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4. N-(5-Chloro-2-(hydroxymethyl)-N-alkyl-arylsulfonamides as γ-secretase inhibitors

Author

Kevin M. Felsenstein, Joanne J. Bronson, C.V.C. Prasad, Graham Johnson, Donna M. Barten, Michael F. Parker, Jason A. Corsa, Jeremy Mock, Valerie Guss, David W. Smith, Charles P. Sloan, Williams Andrew, Owen Brendan Wallace, Steven Hansel, Craig Polson, Keavy Daniel J, Milind Deshpande, Bergstrom Carl P, Henry H. Wang, Wai Y. Lau, and Ming Zheng

Subjects
Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Mice, Transgenic, Biochemistry, Chemical synthesis, Mice, chemistry.chemical_compound, In vivo, Drug Discovery, Animals, Hydroxymethyl, Molecular Biology, Alkyl, chemistry.chemical_classification, Sulfonamides, Amyloid beta-Peptides, Molecular Structure, biology, Chemistry, Organic Chemistry, Brain, Biological activity, Sulfonamide, Enzyme inhibitor, biology.protein, Molecular Medicine, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase, Protein Binding
Abstract

A series of N-alkylbenzenesulfonamides were developed from a high throughput screening hit. Classic and parallel synthesis strategies were employed to produce compounds with good in vitro and in vivo gamma-secretase activity.

Published
2007
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5. Dark Sectors 2016 Workshop: Community Report

Author

Jim Alexander, Jim, Alexander, Marco, Battaglieri, Bertrand, Echenard, Rouven, Essig, Matthew, Graham, Eder, Izaguirre, John, Jaros, Gordan, Krnjaic, Jeremy, Mardon, David, Morrissey, Tim, Nelson, Maxim, Perelstein, Matt, Pyle, Adam, Ritz, Philip, Schuster, Brian, Shuve, Natalia, Toro, Richard, G. Water, Daniel, Akerib, Haipeng, An, Konrad, Aniol, Arnquist, Isaac J., Asner, David M., Back, Henning O., Keith, Baker, Nathan, Baltzell, Dipanwita, Banerjee, Brian, Batell, Daniel, Bauer, James, Beacham, Jay, Benesch, James, Bjorken, Nikita, Blinov, Celine, Boehm, Mariangela, Bondí, Walter, Bonivento, Fabio, Bossi, Brodsky, Stanley J., Ran, Budnik, Stephen, Bueltmann, Bukhari, Masroor H., Raymond, Bunker, Massimo, Carpinelli, Concetta, Cartaro, David, Cassel, Gianluca Cavoto, Andrea, Celentano, Animesh, Chaterjee, Saptarshi, Chaudhuri, Gabriele, Chiodini, Hsiao-Mei Sherry Cho, Church, Eric D., Cooke, D. A., Jodi, Cooley, Robert, Cooper, Ross, Corliss, Paolo, Crivelli, Francesca, Curciarello, Annalisa, D. Angelo, Hooman, Davoudiasl, Marzio De Napoli, Vita, Raffaella, Achim, Denig, Patrick, Deniverville, Abhay, Deshpande, Ranjan, Dharmapalan, Bogdan, Dobrescu, Sergey, Donskov, Raphael, Dupre, Juan, Estrada, Stuart, Fegan, Torben, Ferber, Clive, Field, Enectali, Figueroa-Feliciano, Alessandra, Filippi, Bartosz, Fornal, Arne, Freyberger, Alexander, Friedland, Iftach, Galon, Susan, Gardner, Francois-Xavier, Girod, Sergei, Gninenko, Andrey, Golutvin, Stefania, Gori, Christoph, Grab, Enrico, Graziani, Keith, Griffioen, Andrew, Haas, Keisuke, Harigaya, Christopher, Hearty, Scott, Hertel, Joanne, Hewett, Andrew, Hime, David, Hitlin, Yonit, Hochberg, Holt, Roy J., Maurik, Holtrop, Hoppe, Eric W., Hossbach, Todd W., Lauren, Hsu, Phil, Ilten, Joe, Incandela, Gianluca, Inguglia, Kent, Irwin, Igal, Jaegle, Johnson, Robert P., Yonatan, Kahn, Grzegorz, Kalicy, Zhong-Bo, Kang, Vardan, Khachatryan, Venelin, Kozhuharov, Krasnikov, N. V., Valery, Kubarovsky, Eric, Kuflik, Noah, Kurinsky, Ranjan, Laha, Gaia, Lanfranchi, Dale, Li, Tongyan, Lin, Mariangela, Lisanti, Kun, Liu, Ming, Liu, Ben, Loer, Dinesh, Loomba, Lyubovitskij, Valery E., Aaron, Manalaysay, Giuseppe, Mandaglio, Jeremiah, Mans, Marciano, W. J., Thomas, Markiewicz, Luca, Marsicano, Takashi, Maruyama, Matveev, Victor A., David, Mckeen, Bryan, Mckinnon, Dan, Mckinsey, Harald, Merkel, Jeremy, Mock, Maria Elena Monzani, Omar, Moreno, Corina, Nantais, Sebouh, Paul, Peskin, Michael Edward, Vladimir, Poliakov, Antonio Davide Polosa, Maxim, Pospelov, Igor, Rachek, Balint, Radics, Mauro Raggi, Nunzio, Randazzo, Blair, Ratcliff, Alessandro, Rizzo, Thomas, Rizzo, Alan, Robinson, Andre, Rubbia, David, Rubin, Dylan, Rueter, Tarek, Saab, Elena, Santopinto, Richard, Schnee, Jessie, Shelton, Gabriele, Simi, Ani, Simonyan, Valeria, Sipala, Oren, Slone, Elton, Smith, Daniel, Snowden-Ifft, Matthew, Solt, Peter, Sorensen, Yotam, Soreq, Stefania, Spagnolo, James, Spencer, Stepan, Stepanyan, Jan, Strube, Michael, Sullivan, Tadepalli, Arun S., Tim, Tait, Mauro, Taiuti, Philip, Tanedo, Rex, Tayloe, Jesse, Thaler, Tran, Nhan V., Sean, Tulin, Tully, Christopher G., Sho, Uemura, Maurizio, Ungaro, Paolo, Valente, Holly, Vance, Jerry, Vavra, Tomer, Volansky, Belina von Krosigk, Andrew, Whitbeck, Mike, Williams, Peter, Wittich, Bogdan, Wojtsekhowski, Wei, Xue, Jong Min Yoon, Hai-Bo, Yu, Jaehoon, Yu, Tien-Tien, Yu, Yue, Zhang, Yue, Zhao, Yiming, Zhong, and Kathryn, Zurek

Subjects
Cosmology and Nongalactic Astrophysics (astro-ph.CO), High Energy Physics - Phenomenology, astro-ph.CO, High Energy Physics - Experiment, Nuclear Experiment, hep-ex, FOS: Physical sciences, hep-ph, nucl-ex, High Energy Physics - Experiment (hep-ex), High Energy Physics - Phenomenology (hep-ph), Nuclear Experiment (nucl-ex), Astrophysics - Cosmology and Nongalactic Astrophysics, Particle Physics - Phenomenology
Abstract

This report, based on the Dark Sectors workshop at SLAC in April 2016, summarizes the scientific importance of searches for dark sector dark matter and forces at masses beneath the weak-scale, the status of this broad international field, the important milestones motivating future exploration, and promising experimental opportunities to reach these milestones over the next 5-10 years., 66 pages, 15 figures, 3 tables. Workshop website and agenda: http://www-conf.slac.stanford.edu/darksectors2016/ https://indico.cern.ch/event/507783/ Editors: J. Alexander, M. Battaglieri, B. Echenard, R. Essig, M. Graham, E. Izaguirre, J. Jaros, G. Krnjaic, J. Mardon, D. Morrissey, T. Nelson, M. Perelstein, M. Pyle, A. Ritz, P. Schuster, B. Shuve, N. Toro, R. Van De Water

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