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BACKGROUND Information and communications technologies are transforming our social interactions and life-styles. One of the most promising applications of information technology is healthcare and wellness management that characterized by early detection of conditions, prevention, and long-term healthcare management. OBJECTIVE The main purpose of this document is to do a study, first about the actual literature about mobile phone applications to measure and control heart-rate and second a study about these applications themselves, analyzing the different app stores more popular nowadays, Google Play Store and iTunes (for Android and iOS devices respectively). METHODS The Web portals and databases that were used to perform the searches are IEEE Explorer, National Center for Biotechnology Information, Springer, ResearchGate, Science Direct and Scopus, taking into account the date of publication from 2010 to 2018, publications in English and Spanish. RESULTS 40 relevant papers have been found related to mobile phone apps to measure and control the heart rate. The results show that of a total of 400 applications found 245 of them are in the Play Store (Android systems) and the remaining 155 were found in the iTunes Store (iOS systems). CONCLUSIONS From the review of the research articles analyzed, it can be said that the most applications found are for Android devices. They occupy 76.53% of the world mobile phone market, while iOS only owns 18.97%.

In the last years, handheld devices have experienced an incredible boost and expansion and that expansion has propitiated the creation of a new software industry of mobile apps. These devices and apps are used in every aspect of life, including one of the most important, like is health care. This paper presents the development and QoE evaluation of an application called “Take care your Heart”, designed to work on devices with iOS operative system embedded. This app is aimed to help people with heart problems, giving them some advice about some aspects of their disease, monitoring the doses of their medicines, saving different activities related to it and calculating their risk of suffering a cardiovascular accident. Knowing the level of satisfaction of our patients through this study will allow us to channel the efforts towards more friendly and accepted application by people with heart diseases.

La terapia celular en la reparacion miocardica se vislumbra como una de las estrategias terapeuticas con mayor futuro en el tratamiento de la insuficiencia cardiaca. Numerosos estudios in vitro recientes apoyan la potencialidad de distintos tipos de celulas madre de diferenciarse hacia los tejidos necesarios para regenerar el tejido miocardico danado, mientras que estudios en animales de experimentacion sugieren que celulas madre de musculo (mioblastos), medula osea (progenitores mesenquimales, endoteliales o hematopoyeticos) e incluso del propio corazon pueden contribuir in vivo a mejorar la contractilidad cardiaca. Estos trabajos han conducido a que diversos grupos hayan iniciado estudios en pacientes con infarto de miocardio. Sin embargo, la utilizacion de la terapia celular en ensayos clinicos no esta desprovista de controversia, fundamentalmente relacionada con la necesidad de aumentar nuestro conocimiento antes de pasar a la aplicacion clinica de estas estrategias terapeuticas. Aunque es fundamental aumentar significativamente el conocimiento de los procesos, no consideramos irrazonable iniciar ensayos clinicos en los que se identifiquen preguntas concretas cuya respuesta nos permita avanzar en esta direccion. Palabras clave: Insuficiencia cardiaca. Celulas madre. Mioblastos. Regeneracion cardiaca. Transdiferenciacion.

BackgroundCardiovascular diseases are the deadliest diseases worldwide, with 17.3 million deaths in 2008 alone. Among them, heart-related deaths are of the utmost relevance; a fact easily proven by the 7.25 million deaths caused by ischemic heart disease alone in that year. The latest advances in smartphones and mHealth have been used in the creation of thousands of medical apps related to cardiology, which can help to reduce these mortality rates. ObjectiveThe aim of this paper is to study the literature on mobile systems and applications currently available, as well as the existing apps related to cardiology from the leading app stores and to then classify the results to see what is available and what is missing, focusing particularly on commercial apps. MethodsTwo reviews have been developed. One is a literature review of mobile systems and applications, retrieved from several databases and systems such as Scopus, PubMed, IEEE Xplore, and Web of Knowledge. The other is a review of mobile apps in the leading app stores, Google play for Android and Apple’s App Store for iOS. ResultsSearch queries up to May 2013 located 406 papers and 710 apps related to cardiology and heart disease. The most researched section in the literature associated with cardiology is related to mobile heart (and vital signs) monitoring systems and the methods involved in the classification of heart signs in order to detect abnormal functions. Other systems with a significant number of papers are mobile cardiac rehabilitation systems, blood pressure measurement, and systems for the detection of heart failure. The majority of apps for cardiology are heart monitors and medical calculators. Other categories with a high number of apps are those for ECG education and interpretation, cardiology news and journals, blood pressure tracking, heart rate monitoring using an external device, and CPR instruction. There are very few guides on cardiac rehabilitation and apps for the management of the cardiac condition, and there were no apps that assist people who have undergone a heart transplant. ConclusionsThe distribution of work in the field of cardiology apps is considerably disproportionate. Whereas some systems have significant research and apps are available, other important systems lack such research and lack apps, even though the contribution they could provide is significant.

J Thorac Cardiovasc Surg Jesus Herreros Gonzalez Palazuelos Molinero, Jose Daniel Saenz de Buruaga, Alejandro Martin Trenor and Diego Martin Raymondi, Sergio Mejia Viana, Alejandro Berenguel Senen, Jorge anomalous coronary origin Supravalvular pulmonary stenosis as a late complication of surgery for http://jtcs.ctsnetjournals.org/cgi/content/full/123/6/1218 located on the World Wide Web at: The online version of this article, along with updated information and services, is

Myocardial regeneration is one of the most promising therapeutic strategies for heart failure patients. Many experimental studies have demonstrated that different types of stem cell can differentiate into myocardial cells and tissues necessary for regeneration of the damaged myocardium, while studies in experimental animals suggest that muscle (myoblast), bone marrow (mesenchymal, endothelial or hematopoietic progenitors) and even heart cells can help to improve heart contractility in vivo. These findings have led several groups to undertake studies in patients with myocardial infarction. However, the use of cellular therapy in clinical trials is not without controversy, mainly related with the need for better knowledge before these therapeutic strategies are used in clinical practice. Although significant enhancement of our knowledge of the processes involved is fundamental, we do not consider it unreasonable to initiate clinical trials in which specific questions are posed, whose answers will allow us to make further progress.

We report a patient with a mitral insufficiency due to myxomatous valve change, with a regurgitation murmur heard principally at aortic area and radiating to the neck base. Even though the topography of the murmur seemed to suggest aortic stenosis, the other auscultation findings and the initial clinical tests clearly supported its source in a mitral insufficiency. The echocardiography allowed us not only to confirm our suspicion, but also to explain this auscultation finding mechanism, to show a severe mitral insufficiency with a anterior and medial jet, which struck the aorta and atrial septum. The surgery found a clear aortic vibration, which disappeared after implanting the mitral protheses. Our case illustrates the value of new diagnostic image techniques to complement the semiologic findings.