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5. Capacity for the management of kidney failure in the International Society of Nephrology South Asia region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA).

Author

Wijewickrama, Eranga, Alam, Muhammad, Bajpai, Divya, Divyaveer, Smita, Iyengar, Arpana, Kumar, Vivek, Qayyum, Ahad, Yadav, Shankar, Yadla, Manjusha, Arruebo, Silvia, Bello, Aminu, Caskey, Fergus, Damster, Sandrine, Donner, Jo-Ann, Jha, Vivekanand, Johnson, David, Levin, Adeera, Malik, Charu, Nangaku, Masaomi, Okpechi, Ikechi, Tonelli, Marcello, Ye, Feng, Singh Shah, Dibya, and Prasad, Narayan

Subjects
Global Kidney Health Atlas, International Society of Nephrology, South Asia, epidemiology, kidney failure, kidney replacement therapy
Abstract

The South Asia region is facing a high burden of chronic kidney disease (CKD) with limited health resources and low expenditure on health care. In addition to the burden of CKD and kidney failure from traditional risk factors, CKD of unknown etiologies from India and Sri Lanka compounds the challenges of optimal management of CKD in the region. From the third edition of the International Society of Nephrology Global Kidney Health Atlas (ISN-GKHA), we present the status of CKD burden, infrastructure, funding, resources, and health care personnel using the World Health Organizations building blocks for health systems in the ISN South Asia region. The poor status of the public health care system and low health care expenditure resulted in high out-of-pocket expenditures for people with kidney disease, which further compounded the situation. There is insufficient country capacity across the region to provide kidney replacement therapies to cover the burden. The infrastructure was also not uniformly distributed among the countries in the region. There were no chronic hemodialysis centers in Afghanistan, and peritoneal dialysis services were only available in Bangladesh, India, Nepal, Pakistan, and Sri Lanka. Kidney transplantation was not available in Afghanistan, Bhutan, and Maldives. Conservative kidney management was reported as available in 63% (n = 5) of the countries, yet no country reported availability of the core CKM care components. There was a high hospitalization rate and early mortality because of inadequate kidney care. The lack of national registries and actual disease burden estimates reported in the region prevent policymakers attention to CKD as an important cause of morbidity and mortality. Data from the 2023 ISN-GKHA, although with some limitations, may be used for advocacy and improving CKD care in the region.

Published
2024

6. Capacity for the management of kidney failure in the International Society of Nephrology North America and the Caribbean region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA).

Author

Lowe-Jones, Racquel, Ethier, Isabelle, Fisher, Lori-Ann, Wong, Michelle, Thompson, Stephanie, Nakhoul, Georges, Sandal, Shaifali, Chanchlani, Rahul, Davison, Sara, Ghimire, Anukul, Jindal, Kailash, Osman, Mohamed, Riaz, Parnian, Saad, Syed, Sozio, Stephen, Tungsanga, Somkanya, Cambier, Alexandra, Arruebo, Silvia, Bello, Aminu, Caskey, Fergus, Damster, Sandrine, Donner, Jo-Ann, Jha, Vivekanand, Johnson, David, Levin, Adeera, Malik, Charu, Nangaku, Masaomi, Okpechi, Ikechi, Tonelli, Marcello, Ye, Feng, Parekh, Rulan, and Anand, Shuchi

Subjects
chronic kidney disease, dialysis nurses, hemodialysis, kidney care funding, kidney transplantation, peritoneal dialysis
Abstract

The International Society of Nephrology Global Kidney Health Atlas charts the availability and capacity of kidney care globally. In the North America and the Caribbean region, the Atlas can identify opportunities for kidney care improvement, particularly in Caribbean countries where structures for systematic data collection are lacking. In this third iteration, respondents from 12 of 18 countries from the region reported a 2-fold higher than global median prevalence of dialysis and transplantation, and a 3-fold higher than global median prevalence of dialysis centers. The peritoneal dialysis prevalence was lower than the global median, and transplantation data were missing from 6 of the 10 Caribbean countries. Government-funded payments predominated for dialysis modalities, with greater heterogeneity in transplantation payor mix. Services for chronic kidney disease, such as monitoring of anemia and blood pressure, and diagnostic capability relying on serum creatinine and urinalyses were universally available. Notable exceptions in Caribbean countries included non-calcium-based phosphate binders and kidney biopsy services. Personnel shortages were reported across the region. Kidney failure was identified as a governmental priority more commonly than was chronic kidney disease or acute kidney injury. In this generally affluent region, patients have better access to kidney replacement therapy and chronic kidney disease-related services than in much of the world. Yet clear heterogeneity exists, especially among the Caribbean countries struggling with dialysis and personnel capacity. Important steps to improve kidney care in the region include increased emphasis on preventive care, a focus on home-based modalities and transplantation, and solutions to train and retain specialized allied health professionals.

Published
2024

9. Global variations in funding and use of hemodialysis accesses: an international report using the ISN Global Kidney Health Atlas

Author

Ghimire, Anukul, Shah, Samveg, Chauhan, Utkarsh, Ibrahim, Kwaifa Salihu, Jindal, Kailash, Kazancioglu, Rumeyza, Luyckx, Valerie A., MacRae, Jennifer M., Olanrewaju, Timothy O., Quinn, Robert R., Ravani, Pietro, Shah, Nikhil, Thompson, Stephanie, Tungsanga, Somkanya, Vachharanjani, Tushar, Arruebo, Silvia, Caskey, Fergus J., Damster, Sandrine, Donner, Jo-Ann, Jha, Vivekanand, Levin, Adeera, Malik, Charu, Nangaku, Masaomi, Saad, Syed, Tonelli, Marcello, Ye, Feng, Okpechi, Ikechi G., Bello, Aminu K., and Johnson, David W.

Published
2024
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10. Current Status and Future Directions of mHealth Interventions for Health System Strengthening in India: Systematic Review

Author

Bassi, Abhinav, John, Oommen, Praveen, Devarsetty, Maulik, Pallab K, Panda, Rajmohan, and Jha, Vivekanand

Subjects
Information technology, T58.5-58.64, Public aspects of medicine, RA1-1270
Abstract

BackgroundWith the exponential increase in mobile phone users in India, a large number of public health initiatives are leveraging information technology and mobile devices for health care delivery. Given the considerable financial and human resources being invested in these initiatives, it is important to ascertain their role in strengthening health care systems. ObjectiveWe undertook this review to identify the published mobile health (mHealth) or telemedicine initiatives in India in terms of their current role in health systems strengthening. The review classifies these initiatives based on the disease areas, geographical distribution, and target users and assesses the quality of the available literature. MethodsA search of the literature was done to identify mHealth or telemedicine articles published between January 1997 and June 2017 from India. The electronic bibliographic databases and registries searched included MEDLINE, EMBASE, Joanna Briggs Institute Database, and Clinical Trial Registry of India. The World Health Organization health system building block framework was used to categorize the published initiatives as per their role in the health system. Quality assessment of the selected articles was done using the Cochrane risk of bias assessment and National Institutes of Health, US tools. ResultsThe combined search strategies yielded 2150 citations out of which 318 articles were included (primary research articles=125; reviews and system architectural, case studies, and opinion articles=193). A sharp increase was seen after 2012, driven primarily by noncommunicable disease–focused articles. Majority of the primary studies had their sites in the south Indian states, with no published articles from Jammu and Kashmir and north-eastern parts of India. Service delivery was the primary focus of 57.6% (72/125) of the selected articles. A majority of these articles had their focus on 1 (36.0%, 45/125) or 2 (45.6%, 57/125) domains of health system, most frequently service delivery and health workforce. Initiatives commonly used client education as a tool for improving the health system. More than 91.2% (114/125) of the studies, which lacked a sample size justification, had used convenience sampling. Methodological rigor of the selected trials (n=11) was assessed to be poor as majority of the studies had a high risk for bias in at least 2 categories. ConclusionsIn conclusion, mHealth initiatives are being increasingly tested to improve health care delivery in India. Our review highlights the poor quality of the current evidence base and an urgent need for focused research aimed at generating high-quality evidence on the efficacy, user acceptability, and cost-effectiveness of mHealth interventions aimed toward health systems strengthening. A pragmatic approach would be to include an implementation research component into the existing and proposed digital health initiatives to support the generation of evidence for health systems strengthening on strategically important outcomes.

Published
2018
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14. Clinical Characteristics and Outcomes of Drug-Induced Acute Kidney Injury Cases

Author

Yousif, Zaid K, Koola, Jejo D, Macedo, Etienne, Cerda, Jorge, Goldstein, Stuart L, Chakravarthi, Rajasekara, Lewington, Andrew, Selewski, David, Zappitelli, Michael, Cruz, Dinna, Tolwani, Ashita, Joy, Melanie S, Jha, Vivekanand, Ramachandran, Raja, Ostermann, Marlies, Yang, Li, Pandya, Bhavna, Acharya, Anjali, Brophy, Patrick, Ponce, Daniela, Steinke, Julia, Bouchard, Josee, Irarrazabal, Carlos E, Irarrazabal, Romina, Boltansky, Andrés, Askenazi, David, Kolhe, Nitin, Granado, Rolando Claure-Del, Benador, Nadine, Castledine, Clare, Davenport, Andrew, Barratt, Jonathan, Bhandari, Sunil, Riley, Alyssa A, Akcan-Arikan, Ayse, Davis, TK, Farmer, Christopher, Hogarth, Michael, Thomas, Mark, Murray, Patrick T, Robinson-Cohen, Cassianne, Nicoletti, Paola, Vaingankar, Sucheta, Mehta, Ravindra, and Awdishu, Linda

Subjects
Kidney Disease, Patient Safety, Renal and urogenital, Good Health and Well Being
Published
2023

15. Transplantation: A Priority in the Healthcare Agenda

Author

Muller, Elmi, Dominguez-Gil, Beatriz, Ahn, Curie, Berenguer, Marina, Cardillo, Massimo, Chatzixiros, Efstratios, Cortesi, Paolo, Herson, Marisa, Ilbawi, Andre, Jha, Vivekanand, Mahillo, Beatriz, Manas, Derek M., Nino-Murcia, Alejandro, Shaheen, Faissal A.M., Stock, Peter, and Potena, Luciano

Published
2025
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16. Santander Statement: Towards Global Convergence in Transplantation: Sufficiency, Transparency, and Oversight

Author

Adamec, Milos, Ahn, Curie, Albreht, Katarina, Almén, Helena, Al Obaidli, Ali Abdul Kareem, Anušić Juričić, Martina, Arrabal, Samuel, Ascher, Nancy, Ashkenazi, Tamar, Avendaño-Solá, Cristina, Avsec, Danica, Badenes, Rafael, Bal, Omer, Ballesté, Chloë, Barquero, Teresita, Be, Alicia, Beltrán, Mauricio, Bengochea, Milka, Beqo, Flutra, Berenguer, Marina, Berishvili, Ekaterina, Bokhorst, Arlinke, Boletis, Ioannis, Bolocan, Vladimir, Koh, Mickey BC, Börgel, Martin, Briceño, Javier, Brix-Zuleger, Martina, Busic, Mirela, Buziuviene, Audrone, Caballero, Xavier, Caamaño, Aimée, Carmona, Mar, Capron, Alexander, Cardillo, Massimo, Carella, Claudia, Castillo, María Esther, Cervantes, Lilia, Chandrasekar, Akila, Chaouali, Mafaten, Chatzixiros, Efstratios, Ciccocioppo, Rachele, Cillo, Umberto, Cloherty, Jenny, Colenbie, Luc, Coll, Elisabeth, Cooper, Matthew, Correa-Rocha, Rafael, Cortesi, Paolo Angelo, Cozzi, Emanuele, Cuende, Natividad, Cuero, César, Antonio Da Silva, Juan, Daga, Domingo, Danielyan, Samvel, Danovitch, Gabriel, de Andrade, Joel, de Angelis, Vincenzo, Dedinska, Ivana, del Río, Francisco J., Delmonico, Francis L., Di Ciaccio, Paola, Doerr, Petra, Domínguez-Gil, Beatriz, Emery, Marie-Pierre, Espinel, Mauricio, Fadhil, Riadh, Foeken, Lydia, Forsberg, Anna, Forsythe, John L. R., Friend, Peter, Gadžijev, Andrej, Gallego, Daniel, Gardiner, Dale, Gatt, Sandra, Gjerek, Jernej, Gondolesi, Gabriel, Haraldsson, Börje, Hasal, Antonín, Hennerbichler, Simone, Hernández-Maraver, Dolores, Herson, Marisa, Hickey, Laura, Humar, Simona, Ilbawi, Andre, Immer, Franz, Izeta, Ander, Hawthorne, Wayne J., Jha, Vivekanand, Joyce, Ruth, Jusinskis, Janis, Kaminski, Artur, Kazancıoğlu, Rümeyza, Kim, Joe, Lentine, Krista L., Fraga, Marta López, Lundin, Kersti, Mahillo, Beatriz, Maier, Philip, Mallet, Laurent, Manas, Derek, Manyalich, Marti, Marco, Jaime, Martin, Dominique E., Martínez-Donate, María Dolores, Martjak, Marge, McGee, Andrew, McPhaden, Marcelle, Menjívar, Ana, Mey, Devi, Mihály, Sándor, Mihelčič, Petra, Miñambres, Eduardo, Mirabet, Sonia, Mojsova Mijovska, Maja, Montrasio, Lorenzo, María Moraleda, Jose, Morales, Fernando, Mueller, Thomas, Muller, Elmi, Musquera, Mireia, Nagral, Sanjay, Nathan, Naomi, Nikolac, Vanja, Niño Murcia, Alejandro, Noel, Luc, O’Sullivan, Siobhan, Oniscu, Gabriel C., Opdam, Helen, Orlando, Giuseppe, Ortega, Noelia, Padilla, Benita, Papatheodoridis, George, Pérez Bech, Eva, Pérez Blanco, Alicia, Pérez Martínez, Antonio, Perojo, Dolores, Pires Silva, Ana, Plattner, Verena, Porte, Robert, Potashnik, Anna, Potena, Luciano, Gilberto Prasca, Tomás, Premužić, Marina, Procaccio, Francesco, Rahmel, Axel, Randazzo, Enrico, Raptis, Dimitri A, Rela, Mohamed, Resanović, Vladimir, Rizzolo, Katherine, Adina Rugescu, Iona, Ruiz-Pérez, Blanca, Sainte-Marie, Isabelle, Angelica Salinas, Maria, Sánchez Ibáñez, Jacinto, Serrano, Roselyn, Shaheen, Faissal A., Shemie, Sam, Snyder, Jon, Marie Sørensen, Ragnhild, Spiro, Michael, Stock, Peter, Subotić-Popović, Andreja, Gracious, Noble, Sureda, Ana, Tassot, Johanna, ten Ham, Renske, Thomson, David, Timbalari, Tatiana, Torres, Martín, Tort, Jaume, Trias, Esteve, Trojan, Diletta, Tsimaratos, Mitchel, Tullius, Stefan G., Van Assche, Kristof, Van der Spiegel, Stefaan, Vatachki, Guenadiy, Velasco, Belén, Villatoro, Matías, Walsh, John, Wang, Haibo, and Waterman, Amy

Published
2025
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17. Santander Global Summit in Transplantation: Supporting Global Convergence in the Shared Goals of Sufficiency, Transparency, and Oversight

Author

Domínguez-Gil, Beatriz, López-Fraga, Marta, Muller, Elmi, Potena, Luciano, Martin, Dominique E., Pérez Blanco, Alicia, Van Assche, Kristof, Oniscu, Gabriel C., Chatzixiros, Efstratios, Jha, Vivekanand, Miñambres, Eduardo, Cuende, Natividad, Forsythe, John L. R., Gardiner, Dale, Nagral, Sanjay, Tullius, Stefan G., Cooper, Matthew, and Delmonico, Francis L.

Published
2025
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19. Long-Term Results from an Open-Label Extension Study of Atacicept for the Treatment of IgA Nephropathy

Author

Barratt, Jonathan, Barbour, Sean, Brenner, Robert, Cooper, Kerry, Wei, Xuelian, Eren, Necmi, Floege, Jürgen, Jha, Vivekanand, Kim, Sung Gyun, Maes, Bart, Phoon, Richard K.S., Singh, Harmeet, Tesař, Vladimír, Lafayette, Richard, Umanath, Kausik, Kopyt, Nelson, Lafayette, Richard, Singh, Harmeet, Yalavarthy, Rajesh, Campbell, Kirk, Gohh, Reginald, Shah, Ankur, Zhang, Jingjing, Kumar, Jayant, Barbour, Sean, Bouquegneau, Antoine, Maes, Bart, Speeckaert, Marijn, Vielhauer, Volker, Hugo, Christian, Nitschke, Martin, Tokgoz, Bulent, Eren, Necmi, Rydzewski, Andrzej, Doulton, Timothy, Power, Albert, Hall, Matthew, Willcocks, Lisa, Tesar, Vladimir, Rychlik, Ivan, Goumenos, Dimitrios, Papagianni, Aikaterini, Stangou, Maria, Boletis, Ioannis, Marinaki, Smaragdi, Stylianou, Konstantinos, Zermpala, Synodi, Ntounousi, Evangelia, Gang, Sishir, Alexander, Suceena, Pandey, Rajendra, Dalal, Sonal, Sunil, R, Khetan, Prakash, Jain, Alok, Park, Hyeong Cheon, Kim, Dong Ki, Kim, Sung Gyun, Kim, Beom Seok, Levidiotis, Vicki, Pedagogos, Eugenia, Francis, Ross, Ryan, Jessica, Phoon, Richard, Yahya, Rosnawati, Nor, Bin Mohd, Safhan, Fariz, Lim, Soo Kun, and Teng, Kok Seng

Published
2024
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20. Enhancing Patterns Accessibility for Visually Impaired Programmers

Author

Kajal, Km, Jha, Vivekanand, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Hassanien, Aboul Ella, editor, Anand, Sameer, editor, Jaiswal, Ajay, editor, and Kumar, Prabhat, editor

Published
2024
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21. Combination of the chemokine receptor type 2 (CCR2) antagonist DMX-200 and candesartan for COVID-19: a randomised controlled trial

Author

Mark Jones, Gagandeep Kang, Thomas L Snelling, Vivekanand Jha, Vinay Rathore, Stephane Heritier, Meg Jardine, Kapil Soni, James Totterdell, Sradha Kotwal, Guy Thwaites, Cheryl Jones, Carol Pollock, Richard Haynes, Katrina Diamante, Abhinav Bassi, Nikita Bathla, Natalie Staplin, Arlen Wilcox, Ashpak Bangi, Gregory Fox, Atul Jindal, Rui Xie, Daniel Vincent O'Hara, Sanjay D'Cruz, Manish Kumar Jain, Louise Burrell, Sharifah Faridah Syed Omar, Gerard Estivill Mercade, Aishwarya Nair, Annelise Decaria, Nicola Abignano, Sabah Siddiqui, Suprava Patel, Anjulata Sahu, Yasmeen Shaikh, Madhavender Jain, Shivam R Kanje, Sanjeev Kumar Vimal, K. Kalyan Chakravarthy, P. Sathish Babu, Yuvraj Singh Cheema, Merlin Moni, and Sivapriya G Nair

Subjects
Medicine
Abstract

Objective To determine whether a chemokine receptor type 2 antagonist, DMX-200 (repagermanium), in combination with an angiotensin receptor blocker, candesartan, improves clinical outcomes in people with COVID-19.Design Prospective, multicentre, double-blind, placebo-controlled trial.Setting Ten acute care hospitals in India.Participants Adults

Published
2024
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22. National health policies and strategies for addressing chronic kidney disease: Data from the International Society of Nephrology Global Kidney Health Atlas.

Author

Neuen, Brendon, Bello, Aminu, Levin, Adeera, Lunney, Meaghan, Osman, Mohamed, Ye, Feng, Ashuntantang, Gloria, Bellorin-Font, Ezequiel, Gharbi, Mohammed, Davison, Sara, Ghnaimat, Mohammad, Harden, Paul, Jha, Vivekanand, Kalantar-Zadeh, Kamyar, Kerr, Peter, Klarenbach, Scott, Kovesdy, Csaba, Luyckx, Valerie, Ossareh, Shahrzad, Perl, Jeffrey, Rashid, Harun, Rondeau, Eric, See, Emily, Saad, Syed, Sola, Laura, Tchokhonelidze, Irma, Tesar, Vladimir, Tungsanga, Kriang, Kazancioglu, Rumeyza, Wang, Angela, Yang, Chih-Wei, Zemchenkov, Alexander, Zhao, Ming-Hui, Jager, Kitty, Caskey, Fergus, Perkovic, Vlado, Jindal, Kailash, Okpechi, Ikechi, Tonelli, Marcello, Feehally, John, Harris, David, and Johnson, David

Abstract

National strategies for addressing chronic kidney disease (CKD) are crucial to improving kidney health. We sought to describe country-level variations in non-communicable disease (NCD) strategies and CKD-specific policies across different regions and income levels worldwide. The International Society of Nephrology Global Kidney Health Atlas (GKHA) was a multinational cross-sectional survey conducted between July and October 2018. Responses from key opinion leaders in each country regarding national NCD strategies, the presence and scope of CKD-specific policies, and government recognition of CKD as a health priority were described overall and according to region and income level. 160 countries participated in the GKHA survey, comprising 97.8% of the worlds population. Seventy-four (47%) countries had an established national NCD strategy, and 53 (34%) countries reported the existence of CKD-specific policies, with substantial variation across regions and income levels. Where CKD-specific policies existed, non-dialysis CKD care was variably addressed. 79 (51%) countries identified government recognition of CKD as a health priority. Low- and low-middle income countries were less likely to have strategies and policies for addressing CKD and have governments which recognise it as a health priority. The existence of CKD-specific policies, and a national NCD strategy more broadly, varied substantially across different regions around the world but was overall suboptimal, with major discrepancies between the burden of CKD in many countries and governmental recognition of CKD as a health priority. Greater recognition of CKD within national health policy is critical to improving kidney healthcare globally.

Published
2023

25. International prevalence patterns of low eGFR in adults aged 18-60 without traditional risk factors from a population-based cross-sectional disadvantaged populations eGFR epidemiology (DEGREE) study

Author

Aekplakorn, Wichai, Anand, Shuchi, Aragón, Aurora, Bernabe-Ortiz, Antonio, Biggeri, Annibale, Burdmann, Emmanuel, Caplin, Ben, Catelan, Dolores, Chulasiri, Pubudu, Cooper, Philip J., Correa-Rotter, Ricardo, Cortés, Sandra, Crampin, Amelia C., de Santiago, Melissa, Dhimal, Meghnath, Doccioli, Chiara, Dorevitch, Samuel, Ferreccio, Catterina, Glaser, Jason, Gonzalez-Quiroz, Marvin, Granadillo, Emily, Gualan, Monsermin, Gummidi, Balaji, Gunawardena, Nalika, Hamilton, Sophie, Hathaway, Michelle, Jakobsson, Kristina, Jarhyan, Prashant, Jha, Vivekanand, John, Oomen, Johnson, Richard J., Kaur, Prabhdeep, Kitiyakara, Chagriya, Kongtip, Pornpimol, Kromhout, Hans, Levin, Adeera, Madero, Magdalena, McLean, Estelle, Miranda, J. Jaime, Mkandawire, Joseph, Mohan, Sailesh, Murali, Sharan, Nair, Devaki, Nakanga, Wisdom, Nitsch, Dorothea, Njoroge, Mary, Nyirenda, Moffat, O'Callaghan-Gordo, Cristina, Pearce, Neil, Poudyal, Anil, Prabhakaran, Dorairaj, Prasad, Narayan, Quirós-Alcalá, Lesliam, Remuzzi, Giuseppe, Robertson, Steven, Rohloff, Peter, Romero-Sandoval, Natalia, Ruiz-Alejos, Andrea, Rutter, Charlotte E., Ruwanpathirana, Thilanga, Sakthivel, Manikandanesan, Saran, Rajiv, Senanayake, Sameera, Shaw, Leah, Singh, Ajay, Smeeth, Liam, Sotomayor, Camilo, Tatapudi, Ravi Raju, Tuiz, Eva, Venkateshmurthy, Nikhil Srinivasapura, Venugopal, Vidhya, Wickramasinghe, S.C., Hathaway, Michelle H., and O’Callaghan-Gordo, Cristina

Published
2025
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28. Correlation of Urinary Soluble CD163 Levels With Disease Activity and Treatment Response in IgA Nephropathy

Author

Zhang, Hong, Perkovic, Vlado, Agarwal, Rajiv, Barbour, Sean, Cattran, Daniel, Cass, Alan, Chan, Tak Mao, Feehally, John, Glassock, Richard, Hladunewich, Michelle A., Hooi, Lai Seong, Jardine, Meg J., Jha, Vivekanand, Johnson, David W., Levin, Adeera, Liu, Zhi-Hong, Lv, Jicheng, Monaghan, Helen, Reich, Heather, Remuzzi, Giuseppe, Wheeler, David C., Wong, Muh Geot, Woodward, Mark, Wu, Yangfeng, Zhao, Minghui, Li, Jingyi, Wong, Muh Goet, Shi, Sufang, and Zan, Jincan

Published
2024
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29. Organization and Structures for Detection and Monitoring of CKD Across World Countries and Regions: Observational Data From a Global Survey

Author

Tungsanga, Somkanya, Fung, Winston, Okpechi, Ikechi G., Ye, Feng, Ghimire, Anukul, Li, Philip Kam-Tao, Shlipak, Michael G., Tummalapalli, Sri Lekha, Arruebo, Silvia, Caskey, Fergus J., Damster, Sandrine, Donner, Jo-Ann, Jha, Vivekanand, Levin, Adeera, Saad, Syed, Tonelli, Marcello, Bello, Aminu K., and Johnson, David W.

Published
2024
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30. The role of complement in kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Alberici, Federico, Antonucci, Luca, Avcin, Tadej, Bagga, Arvind, Bajema, Ingeborg M., Blasco, Miquel, Chauvet, Sophie, Cook, H. Terence, Cravedi, Paolo, Dragon-Durey, Marie-Agnès, Fischer, Lauren, Fogo, Agnes B., Frazer-Abel, Ashley, Frémeaux-Bacchi, Véronique, Görlich, Nina, Haas, Mark, Humphreys, Alister, Jha, Vivekanand, Jauhal, Arenn, Kavanagh, David, Kronbichler, Andreas, Lafayette, Richard A., Lanning, Lynne D., Lemaire, Mathieu, Le Quintrec, Moglie, Licht, Christoph, Liew, Adrian, McAdoo, Steve, Medjeral-Thomas, Nicholas R., Meroni, Pier Luigi, Morelle, Johann, Nester, Carla M., Praga, Manuel, Ramachandran, Raja, Reich, Heather N., Remuzzi, Giuseppe, Rodríguez de Córdoba, Santiago, Robinson, Gary, Ronco, Pierre, Rossing, Peter, Salant, David J., Sethi, Sanjeev, Silkjaer, Marianne, Song, Wen-chao, Spoleti, Fabrizio, Taylor, Ronald P., van de Kar, Nicole C.A.J., van Kooten, Cees, Woodward, Len, Zhang, Yuzhou, Zipfel, Peter F., Zuccato, Marco, Vivarelli, Marina, Barratt, Jonathan, Beck, Laurence H., Jr., Fakhouri, Fadi, Gale, Daniel P., Goicoechea de Jorge, Elena, Mosca, Marta, Noris, Marina, Pickering, Matthew C., Susztak, Katalin, Thurman, Joshua M., Cheung, Michael, King, Jennifer M., Jadoul, Michel, Winkelmayer, Wolfgang C., and Smith, Richard J.H.

Published
2024
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31. Rationale, Design, and Intervention Development of a Mobile Health–Led Primary Care Program for Management of Type 2 Diabetes in Rural Thailand: Protocol for a SMARThealth Diabetes Study

Author

Methee Chanpitakkul, Devarsetty Praveen, Renu John, Arpita Ghosh, Salyaveth Lekagul, Malulee Kaewhiran, Kriang Tungsanga, and Vivekanand Jha

Subjects
Medicine, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

BackgroundNoncommunicable diseases (NCDs), particularly diabetes and chronic kidney diseases, pose a significant health burden in Thailand, especially among socioeconomically disadvantaged populations. The existing primary health care system faces challenges in providing optimal care for NCDs due to inadequate primary care workforce. The SMARThealth program offers a technology-based solution to enhance NCD management through task-sharing among nonphysician health care workers. ObjectiveThis study aims to adapt and implement the SMARThealth Diabetes program in rural Thailand to improve diabetes management. The main objectives are to (1) adapt, validate, and integrate the SMARThealth Diabetes program for improving the management of type 2 diabetes mellitus at the primary health care level; and (2) to determine the feasibility and acceptability of the SMARThealth Diabetes program in rural communities of Thailand. MethodsA pragmatic, type 2 hybrid effectiveness or implementation, parallel-group cluster randomized controlled trial of 12 months duration and involving 51 subdistrict health offices in rural communities of Kamphaeng Phet province, Thailand, will be conducted. The intervention arm will receive the SMARThealth Diabetes program, including workforce restructuring, clinical decision support system, and continuous performance monitoring, while the control arm will continue with usual practice. Data will be collected using the SMARThealth platform and will be stored on a server in Thailand. The primary outcome measure will be the change in mean hemoglobin A1c (HbA1c) measured at randomization and 12 months from randomization between the intervention and control clusters. Secondary outcomes will include the difference in change in albuminuria status, estimated glomerular filtration rate, systolic blood pressure, and low-density lipoprotein cholesterol level. The analysis for change in HbA1c between baseline and end of study will be performed using linear mixed models. Any imbalances between the 2 arms will be addressed by sensitivity analyses. Additionally, a mixed methods process evaluation will be conducted to assess the implementation process, that will include in-depth interviews and focus group discussions, in addition to the quantitative data collected during the implementation process. The qualitative data will be thematically analyzed to explore factors that promote or inhibit the implementation and maintenance of the program. ResultsThe data collection commenced in November 2022, and the results will be ready for publication by the first quarter of 2025. Effectiveness of the intervention package will be assessed by change in mean HbA1c measures, and detailed feasibility, barriers, and enablers for the implementation of the intervention will be documented through a detailed process evaluation. ConclusionsThe study protocol outlines a novel approach to enhancing diabetes management in rural Thailand through digital technology–based interventions that will facilitate task-sharing among health care workers. This can help inform future strategies for improving NCD care in low-resource settings globally. Trial RegistrationThai Clinical Trials Registry TCTR20200322006; https://www.thaiclinicaltrials.org/show/TCTR20200322006 International Registered Report Identifier (IRRID)DERR1-10.2196/59266

Published
2024
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32. Investigating Kidney Disease

Author

Srikantharajah, Mukunthan, Doshi, Rukma, Banerjee, Debasish, Jha, Vivekanand, Annear, Nicholas M. P., Banerjee, Debasish, editor, Jha, Vivekanand, editor, and Annear, Nicholas M.P., editor

Published
2023
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34. Diabetes and CKD

Author

Murphy, Daniel, Jha, Vivekanand, Banerjee, Debasish, Banerjee, Debasish, editor, Jha, Vivekanand, editor, and Annear, Nicholas M.P., editor

Published
2023
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38. The Efficacy and Safety of Reduced-Dose Oral Methylprednisolone in High-Risk Immunoglobulin A Nephropathy

Author

Levin, Adeera, Cattran, Daniel, Johnson, David W., Wheeler, David, Flöge, Jürgen, Woodward, Mark, Jardine, Meg, Zhao, Ming-hui, Agarwal, Rajiv, Glassock, Richard, Chan, Tak Mao, Wu, Yangfeng, Liu, Zhihong, Kim, Dana, Lv, Jicheng, Hladunewich, Michelle, Jha, Vivekanand, Hooi, Lai Seong, Monaghan, Helen, Shan, Sana, Reich, Heather N., Barbour, Sean, Billot, Laurent, Zhang, Hong, Perkovic, Vlado, and Wong, Muh Geot

Published
2024
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39. Systematic Review of Kidney Injury Biomarkers for the Evaluation of CKD of Uncertain Etiology

Author

Amador, Juan José, Bhalla, Vivek, Brooks, Daniel, Claudel, Sophie E., Crowe, Jennifer, Arias-Hidalgo, Mariela, Engel, Lawrence S., Franceschini, Nora, Friedman, David, García-Trabanino, Ramón, González-Quiroz, Marvin, Jarquín, Emmanuel, Jha, Vivekanand, Joubert, Bonnie, Kesler, Karen, Lebov, Jill, Levin, Adeera, Mendley, Susan, Mohan, Sumit, Navas-Acien, Ana, Parsa, Afshin, Scammell, Madeleine K., and Waikar, Sushrut S.

Published
2024
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41. Availability, coverage, and scope of health information systems for kidney care across world countries and regions.

Author

See, Emily J, Bello, Aminu K, Levin, Adeera, Lunney, Meaghan, Osman, Mohamed A, Ye, Feng, Ashuntantang, Gloria E, Bellorin-Font, Ezequiel, Benghanem Gharbi, Mohammed, Davison, Sara, Ghnaimat, Mohammad, Harden, Paul, Htay, Htay, Jha, Vivekanand, Kalantar-Zadeh, Kamyar, Kerr, Peter G, Klarenbach, Scott, Kovesdy, Csaba P, Luyckx, Valerie, Neuen, Brendon, O'Donoghue, Donal, Ossareh, Shahrzad, Perl, Jeffrey, Rashid, Harun Ur, Rondeau, Eric, Syed, Saad, Sola, Laura, Tchokhonelidze, Irma, Tesar, Vladimir, Tungsanga, Kriang, Kazancioglu, Rumeyza Turan, Wang, Angela Yee-Moon, Yang, Chih-Wei, Zemchenkov, Alexander, Zhao, Ming-Hui, Jager, Kitty J, Caskey, Fergus, Perkovic, Vlado, Jindal, Kailash K, Okpechi, Ikechi G, Tonelli, Marcello, Feehally, John, Harris, David C, and Johnson, David W

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Health Services, Clinical Research, Patient Safety, Prevention, Kidney Disease, Health and social care services research, 8.1 Organisation and delivery of services, Renal and urogenital, Good Health and Well Being, Cross-Sectional Studies, Developing Countries, Health Information Systems, Humans, Kidney, Renal Insufficiency, Chronic, chronic kidney disease, end-stage kidney disease, health information systems, kidney replacement therapy, registries, Urology & Nephrology, Clinical sciences
Abstract

BackgroundHealth information systems (HIS) are fundamental tools for the surveillance of health services, estimation of disease burden and prioritization of health resources. Several gaps in the availability of HIS for kidney disease were highlighted by the first iteration of the Global Kidney Health Atlas.MethodsAs part of its second iteration, the International Society of Nephrology conducted a cross-sectional global survey between July and October 2018 to explore the coverage and scope of HIS for kidney disease, with a focus on kidney replacement therapy (KRT).ResultsOut of a total of 182 invited countries, 154 countries responded to questions on HIS (85% response rate). KRT registries were available in almost all high-income countries, but few low-income countries, while registries for non-dialysis chronic kidney disease (CKD) or acute kidney injury (AKI) were rare. Registries in high-income countries tended to be national, in contrast to registries in low-income countries, which often operated at local or regional levels. Although cause of end-stage kidney disease, modality of KRT and source of kidney transplant donors were frequently reported, few countries collected data on patient-reported outcome measures and only half of low-income countries recorded process-based measures. Almost no countries had programs to detect AKI and practices to identify CKD-targeted individuals with diabetes, hypertension and cardiovascular disease, rather than members of high-risk ethnic groups.ConclusionsThese findings confirm significant heterogeneity in the global availability of HIS for kidney disease and highlight important gaps in their coverage and scope, especially in low-income countries and across the domains of AKI, non-dialysis CKD, patient-reported outcomes, process-based measures and quality indicators for KRT service delivery.

Published
2021

44. An update on the global disparities in kidney disease burden and care across world countries and regions

Author

Abu-Alfa, Ali K., Amouzegar, Atefeh, Anand, Shuchi, Arogundade, Fatiu Abiola, Ashuntantang, Gloria E., Bavanandan, Sunita, Coppo, Rosanna, Diongole, Hassane M., Divyaveer, Smita, Ekrikpo, Udeme E., Ethier, Isabelle, Fung, Winston Wing-Shing, Gaipov, Abduzhappar, Ghimire, Anukul, Houston, Ghenette, Ibrahim, Kwaifa Salihu, Irish, Georgina, Jindal, Kailash, Kelly, Dearbhla M., Lightstone, Liz, Madero, Magdalena, Nalado, Aisha M., Neuen, Brendon L., Olanrewaju, Timothy O., Osman, Mohamed A., Parekh, Rulan S., Petrova, Anna, Prasad, Narayan, Prikhodina, Larisa, Racki, Sanjin, Riaz, Parnian, Saad, Syed, Sakajiki, Aminu Muhammad, Savaj, Shokoufeh, Singh Shah, Dibya, Suzuki, Yusuke, Tesar, Vladimir, Tiv, Sophanny, Tungsanga, Somkanya, Tzanno-Martins, Carmen, Viecelli, Andrea, Wang, Angela Yee-Moon, Wong, Muh Geot, Zaidi, Deenaz, Bello, Aminu K, Okpechi, Ikechi G, Levin, Adeera, Ye, Feng, Damster, Sandrine, Arruebo, Silvia, Donner, Jo-Ann, Caskey, Fergus J, Cho, Yeoungjee, Davids, M Razeen, Davison, Sara N, Htay, Htay, Jha, Vivekanand, Lalji, Rowena, Malik, Charu, Nangaku, Masaomi, See, Emily, Sozio, Stephen M, Tonelli, Marcello, Wainstein, Marina, Yeung, Emily K, and Johnson, David W

Published
2024
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45. Kidney biopsies among persons living in hotspots of CKDu: a position statement from the International Society of Nephrology’s Consortium of Collaborators on CKDu

Author

Anand, Shuchi, Avila-Casado, Carmen, Bavanandan, Sunita, Bajpai, Divya, Behera, Suman, Brown, Jared M., Caplin, Ben, Daniel, Christoph, de Broe, Marc, Enghard, Philipp, Fuentes, Alejandro Ferreiro, Fire, Andrew Z., Fischer, Rebecca S.B., Friedman, David, Garcia, Pablo, González-Quiroz, Marvin, Herath, Chula, Honsova, Eva, Jha, Vivekanand, Johnson, Richard J., Kanjanabuch, Talerngsak, Kambham, Neeraja, Bandi, Varun Kumar, Levin, Adeera, Madero, Magdalena, Mandayam, Sreedhar, Mikhailov, Alexei, Nanayakkara, Nishantha, Nishanthi, Nadeesha, Nlandu, Yannick M., Pippias, Maria, Prasad, Narayan, Alam, Muhammad Rafiqul, Polo, Vicente Sanchez, Seshan, Surya V., Sheikh-Hamad, David, Singh, Geetika, Strasma, Anna, Tzanno-Martins, Carmen, Ulasi, Ifeoma, Vervaet, Benjamin A., Waikar, Sushrut S., Wijewickrama, Eranga, Wijkström, Julia, Yang, Chih-Wei, Paolo, Vicente Sanchez, and Courville, Karen

Published
2024
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48. A community-based intervention to improve screening, referral and follow-up of non-communicable diseases and anaemia amongst pregnant and postpartum women in rural India: study protocol for a cluster randomised trial

Author

Hirst, Jane Elizabeth, Votruba, Nicole, Billot, Laurent, Arora, Varun, Rajan, Eldho, Thout, Sudhir Raj, Peiris, David, Patel, Anushka, Norton, Robyn, Mullins, Edward, Sharma, Ankita, Kennedy, Stephen, Jha, Vivekanand, and Praveen, Devarsetty

Published
2023
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