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21 results on '"Ji, Hongmiao"'

1. Chewing ability and its associated factors among community‐dwelling older adults in Chengdu, China: A cross‐sectional study.

Author

Ji, Hongmiao, Tang, Sikai, and Liu, Xing

Subjects
*RISK assessment, *CROSS-sectional method, *INDEPENDENT living, *T-test (Statistics), *RESEARCH funding, *LOGISTIC regression analysis, *QUESTIONNAIRES, *INTERVIEWING, *MULTIVARIATE analysis, *DESCRIPTIVE statistics, *CHI-squared test, *CHEWING gum, *CEREBELLAR ataxia, *ODDS ratio, *MASTICATION, *CONFIDENCE intervals, *DATA analysis software, *EDUCATIONAL attainment
Abstract

Aim: To investigate the current status of chewing ability and analyze the risk factors among Chinese community‐dwelling older adults. Methods: In this cross‐sectional study, color‐changeable gum and a color difference meter were used to assess chewing ability in the population. The statistical analysis employed multivariate logistic regression models to identify and quantify the factors influencing chewing ability. Results: A total of 373 community‐dwelling adults aged 65 and older in Chengdu, in the west of China, were included in this study; 64 individuals (17.2%) exhibited signs of poor chewing ability. Female (odds ratio [OR]: 0.124, 95% CI: 0.057–0.268, p <.001), education level with college degree and above (OR: 0.114, 95% CI: 0.030–0.434, p =.001), number of teeth less than 20 (OR: 5.401, 95% CI: 2.509–11.626, p <.001), and decreased oral diadochokinesis (OR: 4.445, 95% CI: 1.775–11.132, p =.001) were significant factors in chewing ability in this study, after adjustment for potential variables. Conclusions: The prevalence of decreased chewing ability among Chinese community‐dwelling older adults was 17.2% and decreased chewing ability was associated with men, lower education level, less than 20 teeth and decreased oral diadochokinesis. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Ultra-localized single cell electroporation using silicon nanowires

Author

Jokilaakso, Nima, Salm, Eric, Chen, Aaron, Millet, Larry, Guevara, Carlos Duarte, Dorvel, Brian, Reddy, Bobby, Jr., Eriksson Karlström, Amelie, Chen, Yu, Ji, Hongmiao, Sooryakumar, Ratnasingham, Bashir, Rashid, Jokilaakso, Nima, Salm, Eric, Chen, Aaron, Millet, Larry, Guevara, Carlos Duarte, Dorvel, Brian, Reddy, Bobby, Jr., Eriksson Karlström, Amelie, Chen, Yu, Ji, Hongmiao, Sooryakumar, Ratnasingham, and Bashir, Rashid

Abstract

Analysis of cell-to-cell variation can further the understanding of intracellular processes and the role of individual cell function within a larger cell population. The ability to precisely lyse single cells can be used to release cellular components to resolve cellular heterogeneity that might be obscured when whole populations are examined. We report a method to position and lyse individual cells on silicon nanowire and nanoribbon biological field effect transistors. In this study, HT-29 cancer cells were positioned on top of transistors by manipulating magnetic beads using external magnetic fields. Ultra-rapid cell lysis was subsequently performed by applying 600-900 mV(pp) at 10 MHz for as little as 2 ms across the transistor channel and the bulk substrate. We show that the fringing electric field at the device surface disrupts the cell membrane, leading to lysis from irreversible electroporation. This methodology allows rapid and simple single cell lysis and analysis with potential applications in medical diagnostics, proteome analysis and developmental biology studies., QC 20130204

Published
2013
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15. Ultra-localized single cell electroporation using silicon nanowires

Author

Jokilaakso, Nima, primary, Salm, Eric, additional, Chen, Aaron, additional, Millet, Larry, additional, Guevara, Carlos Duarte, additional, Dorvel, Brian, additional, Reddy, Bobby, additional, Karlstrom, Amelie Eriksson, additional, Chen, Yu, additional, Ji, Hongmiao, additional, Sooryakumar, Ratnasingham, additional, and Bashir, Rashid, additional

Published
2013
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20. PREDICTION OF FLOW AND HEAT TRANSFER CHARACTERISTICS IN MICRO-COUETTE FLOW

Author

Xue, Hong and Ji, Hongmiao

Abstract

In this study, direct simulation Monte Carlo (DSMC) method, the Navier-Stokes equations, and the Burnett equations are applied to micro-Couette flow to investigate flow and heat transfer characteristics in the slip and transition flow regimes. The unique solutions of the Burnett equations are obtained through determination of additional boundary condition for pressure using the results of DSMC. The effect of rarefaction on velocity, temperature, and pressure distributions is analyzed. The nondimensional parameter PrE characterizing convective heat transfer in Coutte flow increases as flow becomes more rarefied. The prediction of shear stress and heat flux at wall shows that the solution of the Burnett equations is superior than that of the Navier-Stokes equations at relatively high Kn number in the slip flow regime, but the Burnett equations with the slip boundary condition, which is proportional to Kn number, cannot be extended to the transition flow regime.

Published
2003
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21. Electrochemical detection of oligonucleotide by attaching redox probes onto its backbone

Author

Siti Rafeah Mohamed Rafei, Hongmiao Ji, Wang Yanping Karen, Cheng Fang, Fang, Cheng, Ji, Hongmiao, Karen, WY, and Rafei, SRM

Subjects
Conductometry, Biomedical Engineering, Biophysics, Oligonucleotides, Biosensing Techniques, Redox, chemistry.chemical_compound, backbone, Electrochemistry, Organic chemistry, Peptide nucleic acid, Chemistry, Oligonucleotide, Hybridization probe, DNA, General Medicine, Equipment Design, Phosphate, linker, Combinatorial chemistry, Equipment Failure Analysis, electrochemical biosensor, Ferrocene, DNA Probes, Linker, Oxidation-Reduction, PNA, Biotechnology
Abstract

An approach was demonstrated to detect oligonucleotide by attaching redox probes onto its backbone. First, peptide nucleic acid (PNA) with a neutral backbone was immobilized onto a gold (Au) electrode surface as a capture. Second,whenthePNAcapture hybridized with a target oligonucleotide (a short DNA), an assembly ofAu–PNA–DNAformed and phosphate groups were thus brought into the assembly from the DNA’s backbone. The linker ion of Zr4+ exhibits a strong coordination interaction with the phosphate group and the carboxylic group. The hybridized target DNA provides the phosphate group while a derivatized redox probe of ferrocene (Fc) carboxyl acid offers the carboxylic group. Therefore, the redox probe can be attached to the phosphate group by the linker to form an assembly of Au–PNA–DNA–Zr–Fc. Its redox process was studied and the detection conditions of oligonucleotide were optimized. A limit of detection of 1.0×10−12Mor ∼2 attomol was reached. Refereed/Peer-reviewed

Published
2010

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