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2 results on '"Jie-mei Yang"'

1. Latent profile analysis and influencing factors of quality of life in pregnant women with gestational diabetes mellitus

Author

Xin-yi Zhou, Yan-feng Wang, Jie-mei Yang, Li-yuan Yang, Wei-jia Zhao, Yan-ling Chen, and Qiao-hong Yang

Subjects
Gestational Diabetes Mellitus, Pregnant woman, Quality of life, Latent profile analysis, Gynecology and obstetrics, RG1-991
Abstract

Abstract Purpose Gestational diabetes mellitus (GDM) negatively affects the quality of life of pregnant women and is influenced by several factors. Research to date treats pregnant women with gestational diabetes as a homogeneous group based on their quality of life. We attempted to identify subgroups based on self-reported quality of life and explored variables associated with subgroups. Methods From September 1, 2020 to November 29, 2020, pregnant women with GDM from two hospitals in Guangdong Province were selected as subjects by convenience sampling method. Medical records provided sociodemographic data, duration of GDM, pregnancy status, and family history of diabetes. Participants completed validated questionnaires for quality of life, anxiety and depression. Latent profile analysis was used to identify profiles of quality of life in pregnant women with GDM, and then a mixed regression method was used to analyze the influencing factors of different profiles. Results A total of 279 valid questionnaires were collected. The results of the latent profile analysis showed that the quality of life of pregnant women with GDM could be divided into two profiles: C1 “high worry-high support” group (75.6%) and C2 “low worry-low support” group (24.4%). Daily exercise duration and depression degree are negative influencing factors, making it easier to enter the C1 group (p

Published
2023
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2. Maternal serum uric acid concentration is associated with the expression of tumour necrosis factor-α and intercellular adhesion molecule-1 in patients with preeclampsia

Author

Zheng Dy, Juan Zhao, Yun Xg, Miao Wang, Jie-Mei Yang, Sun L, and Xing-Tong Zhang

Subjects
0301 basic medicine, Gestational hypertension, Adult, medicine.medical_specialty, Pathology, Necrosis, Subcutaneous Fat, Inflammation, Blood Pressure, Urine, 030204 cardiovascular system & hematology, Preeclampsia, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pre-Eclampsia, Pregnancy, Internal medicine, Internal Medicine, medicine, Humans, business.industry, Tumor Necrosis Factor-alpha, medicine.disease, Intercellular Adhesion Molecule-1, Up-Regulation, Uric Acid, 030104 developmental biology, Endocrinology, Blood pressure, chemistry, Case-Control Studies, Uric acid, Female, medicine.symptom, Inflammation Mediators, business, Biomarkers
Abstract

We aimed to investigate whether there is a correlation between elevated serum uric acid (SUA) concentration and endothelial inflammatory response in women with preeclampsia (PE). On the basis of clinical and laboratory findings, patients were assigned to three groups: normal blood pressure (Control (Con)), gestational hypertension (GH) and PE (n=50 in each group). SUA concentration was measured by spectrophotometry, and serum tumour necrosis factor-α (TNF-α) and intercellular adhesion molecule-1 (ICAM-1) levels were measured by enzyme-linked immunosorbent assay. Western blotting and immunohistochemical staining were also used to detect the changes in TNF-α and ICAM-1 expression in subcutaneous fat tissue. PE patients showed significantly higher systolic and diastolic blood pressures compared with Con and GH pregnant women (P=0.02 and P=0.02, respectively). The changes of body mass index (ΔBMI) before and after pregnancy and 24-h urine protein were significantly different among the three groups (P

Published
2015

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