Search

Your search keyword '"Jin, Rong‐Rong"' showing total 16 results
Start Over Author "Jin, Rong‐Rong"
16 results on '"Jin, Rong‐Rong"'

5. Characteristics of H7N9 avian influenza pneumonia: a retrospective analysis of 17 cases

Author

Yu, Wen‐Qing, primary, Ji, Ning‐Fei, additional, Ding, Ming‐Dong, additional, Gu, Cheng‐Jing, additional, Ma, Yuan, additional, Wu, Zhen‐Zhen, additional, Wang, Yan‐Li, additional, Wu, Chao‐Jie, additional, Dai, Gui‐Hong, additional, Chen, Yan, additional, Jin, Rong‐Rong, additional, Tan, Yi‐Bin, additional, Yang, Zhu, additional, Zhou, Da‐Ming, additional, Xian, Jian‐Chun, additional, Xu, Hong‐Tao, additional, and Huang, Mao, additional

Published
2020
Full Text
View/download PDF

6. Downregulation of miR-4772-3p promotes enhanced regulatory T cell capacity in malignant pleural effusion by elevating Helios levels

Author

Yu, Wen-Qing, primary, Ji, Ning-Fei, additional, Gu, Cheng-Jing, additional, Sun, Zhi-Xiao, additional, Wang, Zheng-Xia, additional, Chen, Zhong-Qi, additional, Ma, Yuan, additional, Wu, Zhen-Zhen, additional, Wang, Yan-Li, additional, Wu, Chao-Jie, additional, Ding, Ming-Dong, additional, Dai, Gui-Hong, additional, Yao, Juan, additional, Jin, Rong-Rong, additional, Huang, Mao, additional, and Zhang, Ming-Shun, additional

Published
2019
Full Text
View/download PDF

13. Correction: Evaluation of a Novel Thermosensitive Heparin-Poloxamer Hydrogel for Improving Vascular Anastomosis Quality and Safety in a Rabbit Model

Author

Zhao, Ying-Zheng, primary, Lv, Hai-Feng, additional, Lu, Cui-Tao, additional, Chen, Li-Juan, additional, Lin, Min, additional, Zhang, Ming, additional, Jiang, Xi, additional, Shen, Xiao-Tong, additional, Jin, Rong-Rong, additional, Cai, Jun, additional, Tian, Xin-Qiao, additional, and Wong, Ho Lun, additional

Published
2013
Full Text
View/download PDF

16. Gelatin nanoparticle-mediated intranasal delivery of substance P protects against 6-hydroxydopamine-induced apoptosis: an in vitro and in vivo study.

Author

Lu CT, Jin RR, Jiang YN, Lin Q, Yu WZ, Mao KL, Tian FR, Zhao YP, and Zhao YZ

Subjects
Administration, Intranasal, Animals, Caspase 3 analysis, Caspase 3 metabolism, Cells, Cultured, Disease Models, Animal, Male, Molecular Structure, Oxidopamine administration & dosage, Oxidopamine pharmacology, PC12 Cells, Rats, Rats, Sprague-Dawley, Structure-Activity Relationship, Substance P chemistry, Substantia Nigra drug effects, Substantia Nigra metabolism, Substantia Nigra pathology, Apoptosis drug effects, Drug Delivery Systems, Gelatin chemistry, Nanoparticles chemistry, Oxidopamine antagonists & inhibitors, Substance P administration & dosage, Substance P pharmacology
Abstract

Background: The aim of this study was to investigate the protective role of intranasally administered substance P-loaded gelatin nanoparticles (SP-GNPs) against 6-hydroxydopamine (6-OHDA)-induced apoptosis in vitro and in vivo, and to provide a new strategy for treating brain pathology, such as Parkinson's disease., Methods: SP-GNPs were prepared by a water-in-water emulsion method, and their stability, encapsulating efficiency, and loading capacity were evaluated. PC-12 cells were used to examine the enhancement of growth and inhibition of apoptosis by SP-GNPs in vitro using MTT assays. In the in vivo study, hemiparkinsonian rats were created by intracerebroventricular injection of 6-OHDA. The rats then received intranasal SP-GNPs daily for 2 weeks. Functional improvement was assessed by quantifying rotational behavior, and the degree of apoptosis was assessed by immunohistochemical staining for caspase-3 in the substantia nigra region., Results: PC-12 cells with 6-OHDA-induced disease treated with SP-GNPs showed higher cell viability than their untreated counterparts, and cell viability increased as the concentration of substance P (SP) increased, indicating that SP could enhance cell growth and inhibit the cell apoptosis induced by 6-OHDA. Rats with 6-OHDA-induced hemiparkinsonism treated with SP-GNPs made fewer rotations and showed less staining for caspase-3 than their counterparts not treated with SP, indicating that SP protects rats with 6-OHDA-induced hemiparkinsonism from apoptosis and therefore demonstrates their functional improvement., Conclusion: Intranasal delivery of SP-GNPs protects against 6-OHDA-induced apoptosis both in vitro and in vivo.

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results