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Additional file 1: Figure S1. Rapid causes of cancer mortality worldwide for females and males, 1990–2019. Figure S2. Tracheal, bronchus, and lung cancer age-standardized mortality rates in 2019 (A) and percent change (%) in age-standardized rates during 1990–2019 (B) for 204 countries and territories by sociodemographic index. Figure S3. The colon and rectal cancer age-standardized mortality rates in 2019 (A) and percent change (%) in the age-standardized rate during 1990–2019 (B) for 204 countries and territories by sociodemographic index. Figure S4. Breast cancer age-standardized mortality rates in 2019 (A) and percent change (%) in age-standardized rates during 1990–2019 (B) for 204 countries and territories by sociodemographic index. Figure S5. Pancreatic cancer age-standardized mortality rates in 2019 (A) and percent change (%) in age-standardized rates during 1990–2019 (B) for 204 countries and territories by sociodemographic index. Figure S6. Local drifts of tracheal, bronchus, and lung cancer mortality attributable to HFPG by SDI quintiles, 1990–2019. Figure S7. Local drifts of colon and rectal cancer mortality attributable to HFPG by SDI quintiles, 1990–2019. Figure S8. Local drifts of breast cancer mortality attributable to HFPG by SDI quintiles, 1990–2019. Figure S9. Local drifts of pancreatic cancer mortality attributable to HFPG by SDI quintiles, 1990–2019. Figure S10. Age distribution of tracheal, bronchus, and lung cancer mortality attributable to HFPG by SDI quintiles, 1990–2019. Figure S11. Age distribution of colon and rectal cancer mortality attributable to HFPG by SDI quintiles, 1990–2019. Figure S12. Age distribution of breast cancer mortality attributable to HFPG by SDI quintiles, 1990–2019. Figure S13. Age distribution of pancreatic cancer mortality attributable to HFPG by SDI quintiles, 1990–2019. Figure S14. Age, period and cohort effects on tracheal, bronchus, and lung cancer mortality attributable to HFPG by SDI quintiles. Figure S15. Age, period and cohort effects on colon and rectal cancer mortality attributable to HFPG by SDI quintiles. Figure S16. Age, period and cohort effects on breast cancer mortality attributable to HFPG by SDI quintiles. Figure S17. Age, period and cohort effects on pancreatic cancer mortality attributable to HFPG by SDI quintiles. Figure S18. Age, period and cohort effects on tracheal, bronchus, and lung cancer mortality attributable to HFPG for representative countries. Figure S19. Age, period and cohort effects on colon and rectal cancer mortality attributable to HFPG for representative countries. Figure S20. Age, period and cohort effects on breast cancer mortality attributable to HFPG for representative countries. Figure S21. Age, period and cohort effects on pancreatic cancer mortality attributable to HFPG for representative countries. Table S1. Percent changes (%) in the age-standardized mortality rate 1990–2019 for all risk factors. Table S2. Trends in cancer mortality attributable to HPFG for females and males across SDI quintiles, 1990 − 2019. Table S3. Trends in tracheal, bronchus, and lung cancer mortality attributable to HPFG for both females and males across SDI quintiles, 1990 − 2019. Table S4. Trends in colon and rectal cancer mortality attributable to HPFG for both females and males across SDI quintiles, 1990 − 2019. Table S5. Trends in breast cancer mortality attributable to HPFG for female across SDI quintiles, 1990 − 2019. Table S6. Trends in pancreatic cancer mortality attributable to HPFG for both females and males across SDI quintiles, 1990 − 2019. Table S7. Trends in cancer mortality attributable to HPFG for both genders in 204 countries and regions, 1990–2019. Table S8. Trends in cancer mortality attributable to HPFG for both females and males in representative countries, 1990–2019. Table S9. Trends in tracheal, bronchus, and lung cancer mortality attributable to HPFG for both females and males in representative countries, 1990–2019. Table S10. Trends in colon and rectal cancer mortality attributable to HPFG for both females and males in representative countries, 1990–2019. Table S11. Trends in breast cancer mortality attributable to HPFG for both females in representative countries, 1990–2019. Table S12. Trends in pancreatic cancer mortality attributable to HPFG for both females and males in representative countries, 1990–2019.

Additional file 1: Table S1. AHA definitions of cardiovascular health by each metric. Table S2. The formula for United States Steatosis Index (USFLI) , fibrosis-4 (FIB-4) and the NAFLD fibrosis score (NFS). Table S3. Stratified analysis of the associations (ORs) between different T2D subgroups. Table S4. Stratified analysis of the associations (HRs) between different T2D subgroups. Table S5. HRs of all-cause, CVD and cancer-related mortality among different T2D subgroups after excluding participants who died within two years of follow-up.

Analysis of the related risks of disease provides a scientific basis for disease prevention and treatment, hospital management, and policy formulation by the changes in disease spectrum of patients in hospital. Retrospective analysis was made to the first diagnosis, age, gender, daily average cost of hospitalized patients, and other factors in the First Affiliated Hospital of Nanjing Medical University during 2006–2013. The top 4 cases were as follows: cardiovascular disease, malignant tumors, lung infections, and noninsulin dependent diabetes mellitus. By the age of disease analysis, we found a younger age trend of cardiovascular disease, and the age of onset of cancer or diabetes was somewhat postponed. The average daily cost of hospitalization and the average daily cost of the main noncommunicable diseases were both on the rise. Noncommunicable diseases occupy an increasingly important position in the constitution of the disease, and they caused an increasing medical burden. People should pay attention to health from the aspects of lifestyle changing. Hospitals should focus on building the appropriate discipline. On the other hand, an integrated government response is required to tackle key risks. Multiple interventions are needed to lower the burden of these diseases and to improve national health.