185 results on '"Jinwal, Umesh K."'
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2. Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy
3. Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement*
4. Synthesis, Stereochemical Analysis, and Derivatization of Myricanol Provide New Probes That Promote Autophagic Tau Clearance
5. Allosteric Heat Shock Protein 70 Inhibitors Rapidly Rescue Synaptic Plasticity Deficits by Reducing Aberrant Tau
6. Synthesis and Initial Evaluation of YM-08, a Blood-Brain Barrier Permeable Derivative of the Heat Shock Protein 70 (Hsp70) Inhibitor MKT-077, Which Reduces Tau Levels
7. Cysteine Reactivity Distinguishes Redox Sensing by the Heat-Inducible and Constitutive Forms of Heat Shock Protein 70
8. Analysis of the Tau-Associated Proteome Reveals That Exchange of Hsp70 for Hsp90 Is Involved in Tau Degradation
9. Cdc37/Hsp90 Protein Complex Disruption Triggers an Autophagic Clearance Cascade for TDP-43 Protein
10. Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance.
11. Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden
12. Cdc37
13. Contributors
14. Akt and CHIP Coregulate Tau Degradation through Coordinated Interactions
15. Bending Tau into Shape: The Emerging Role of Peptidyl-Prolyl Isomerases in Tauopathies
16. Hsp90-interacting Co-chaperones and their Family Proteins in Tau Regulation: Introducing a Novel Role for Cdc37L1
17. A commentary on: Modulating molecular chaperones improves sensory fiber recovery and mitochondrial function in diabetic peripheral neuropathy
18. Natural products as a rich source of tau-targeting drugs for Alzheimerʼs disease
19. Cell-Based Assays for Regulators of Tau Biology
20. Exploiting the Diversity of the Heat-Shock Protein Family for Primary and Secondary Tauopathy Therapeutics
21. Therapeutic Potential of the Hsp90/Cdc37 Interaction in Neurodegenerative Diseases
22. Chaperone signalling complexes in Alzheimerʼs disease
23. Cloning, sequencing and structural features of a novel Streptococcus lipase
24. Purification and characterization of an alkaline lipase from a newly isolated Pseudomonas mendocina PK-12CS and chemoselective hydrolysis of fatty acid ester
25. Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden
26. The Diarylheptanoid (+)-aR,11S-Myricanol and Two Flavones from Bayberry (Myrica cerifera) Destabilize the Microtubule-Associated Protein Tau
27. An optimized InCell Western screening technique identifies hexachlorophene as a novel potent TDP43 targeting drug
28. Data from SILAC-based quantitative analysis of lysates from mouse microglial cells treated with Withaferin A (WA)
29. Identification of Apo B48 and other novel biomarkers in amyotrophic lateral sclerosis patient fibroblasts
30. Identification and quantitative analysis of cellular proteins affected by treatment with withaferin a using a SILAC-based proteomics approach
31. Hsp70 ATPase Modulators as Therapeutics for Alzheimer’s and other Neurodegenerative Diseases
32. Imbalance of Hsp70 family variants fosters tau accumulation
33. Glucose-regulated Protein 94 Triage of Mutant Myocilin through Endoplasmic Reticulum-associated Degradation Subverts a More Efficient Autophagic Clearance Mechanism
34. Cysteine Reactivity Distinguishes Redox Sensing by the Heat-Inducible and Constitutive Forms of Heat Shock Protein 70
35. DnaJA1 Antagonizes Constitutive Hsp70-Mediated Stabilization of Tau
36. Correction: Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance
37. ApoER2 Function in the Establishment and Maintenance of Retinal Synaptic Connectivity
38. A New Anti-Depressive Strategy for the Elderly: Ablation of FKBP5/FKBP51
39. Allosteric Drugs: The Interaction of Antitumor Compound MKT-077 with Human Hsp70 Chaperones
40. The Hsp90 Kinase Co-chaperone Cdc37 Regulates Tau Stability and Phosphorylation Dynamics
41. ChemInform Abstract: Identification of Dihydropyridines that Reduce Cellular Tau Levels.
42. Identification of dihydropyridines that reduce cellular tau levels
43. The Diarylheptanoid (+)-aR,11S-Myricanol and Two Flavones from Bayberry (Myrica cerifera) Destabilize the Microtubule-Associated Protein Tau
44. P3-425: Chaperone-mediated modulation of tau aggregation correlates with modifications in tau pathology and synaptic plasticity
45. P1-370: The early involvement of chaperones in tau pathogenesis
46. Hsc70 Rapidly Engages Tau after Microtubule Destabilization
47. The Hsp90 Cochaperone, FKBP51, Increases Tau Stability and Polymerizes Microtubules
48. Facilitating Akt Clearance via Manipulation of Hsp70 Activity and Levels
49. P2‐198: Chemical manipulation of Hsp70 activity regulates tau processing
50. Identification of two mariner-like elements in the genome of the mosquito Ochlerotatus atropalpus
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