311 results on '"Johnson, F. Brad"'
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2. SLC25A51 is a mammalian mitochondrial NAD+ transporter
3. TERRA G-quadruplex RNA interaction with TRF2 GAR domain is required for telomere integrity
4. Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere damage repair
5. Computational assessment of miRNA binding to low and high expression HLA-DPB1 allelic sequences
6. APC and P53 mutations synergise to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer.
7. APCandP53mutations synergise to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer
8. Fundamentals of G-quadruplex biology
9. What have we learned so far on the molecular pathogenesis of Werner syndrome using mutant mouse models of this human progeroid disorder?
10. Understanding the evolving phenotype of vascular complications in telomere biology disorders
11. Data from Identification of Chimeric Antigen Receptors That Mediate Constitutive or Inducible Proliferation of T Cells
12. Supplemental Methods, Tables 1 - 3, Figures 1 - 16 from Identification of Chimeric Antigen Receptors That Mediate Constitutive or Inducible Proliferation of T Cells
13. Supplementary Data from Functional Unresponsiveness and Replicative Senescence of Myeloid Leukemia Antigen–specific CD8+ T Cells After Allogeneic Stem Cell Transplantation
14. Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
15. Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease
16. Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere length maintenance
17. Author Correction: Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
18. Correction to: HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression
19. APC and P53 mutations synergize to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer
20. Inactivation of Yeast Isw2 Chromatin Remodeling Enzyme Mimics Longevity Effect of Calorie Restriction via Induction of Genotoxic Stress Response
21. GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells
22. The methyltransferase enzymes KMT2D, SETD1B, and ASH1L are key mediators of both metabolic and epigenetic changes during cellular senescence
23. Author response: GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells
24. Contributions of Telomere Biology to Human Age-Related Disease
25. List of Contributors
26. Patient induced pluripotent stem cell-derived hepatostellate organoids establish a basis for liver pathologies in telomeropathies
27. Do the telomere ends justify the physical means?
28. APCand P53mutations synergise to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer
29. Publisher Correction: Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease
30. Comparisons of telomere lengths in peripheral blood and cerebellum in Alzheimer's disease
31. Extradenticle Protein is a Selective Cofactor for the Drosophila Homeotics: Role of the Homeodomain and YPWM Amino Acid Motif in the Interaction
32. Telomere stability and carcinogenesis: an off-again, on-again relationship
33. Histone H4 lysine 16 acetylation regulates cellular lifespan
34. GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells
35. Isolation of G-Quadruplex DNA Using NMM-Sepharose Affinity Chromatography
36. Computational Approaches to the Detection and Analysis of Sequences with Intramolecular G-Quadruplex Forming Potential
37. PinX1 the tail on the chromosome
38. Orthotopic Transplantation and Engraftment of Human Induced Pluripotent Stem Cell-Derived Alveolar Progenitor Cells into Murine Lungs
39. G‐quadruplexes in fibrotic scars may open new therapeutic avenues for wound healing
40. Rap1‐mediated nucleosome displacement can regulate gene expression in senescent cells without impacting the pace of senescence
41. P010 NGS variant allele interpretation and family haplotypes
42. P009 HLA haplotype dropout with onset of acute myeloid leukemia
43. Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential
44. Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis
45. Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae
46. Werner syndrome protein prevents DNA breaks upon chromatin structure alteration
47. Evidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence
48. Potential Roles for G-Quadruplexes in Mitochondria
49. Deletion of ULS1 confers damage tolerance in sgs1 mutants through a Top3-dependent D-loop mediated fork restart pathway
50. Chapter 7 - Contributions of Telomere Biology to Human Age-Related Disease
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