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1. Corrigendum to 'Predictors of ASDAS-CRP inactive disease in axial spondyloarthritis during treatment with TNF-inhibitors: data from the EuroSpA collaboration' [Seminars in Arthritis and Rheumatism 56 (2022) 1-13/152081]

Author: Ørnbjerg, L.M., Linde, L., Georgiadis, S., Rasmussen, S.H., Lindström, U., Askling, J., Michelsen, B., Giuseppe, D.D., Wallman, J.K., Pavelka, K., Závada, J., Nissen, M.J., Jones, G.T., Relas, H., Pirilä, L., Tomšič, M., Rotar, Z., Geirsson, A.J., Gudbjornsson, B., Kristianslund, E.K., Horst-Bruinsma, I.E. van der, Loft, A.G., Laas, K., Iannone, F., Corrado, A., Ciurea, A., Santos, M.J., Santos, H. Dos, Codreanu, C., Akkoc, N., Gunduz, O.S., Glintborg, B., Østergaard, M., Hetland, M.L., Ørnbjerg, L.M., Linde, L., Georgiadis, S., Rasmussen, S.H., Lindström, U., Askling, J., Michelsen, B., Giuseppe, D.D., Wallman, J.K., Pavelka, K., Závada, J., Nissen, M.J., Jones, G.T., Relas, H., Pirilä, L., Tomšič, M., Rotar, Z., Geirsson, A.J., Gudbjornsson, B., Kristianslund, E.K., Horst-Bruinsma, I.E. van der, Loft, A.G., Laas, K., Iannone, F., Corrado, A., Ciurea, A., Santos, M.J., Santos, H. Dos, Codreanu, C., Akkoc, N., Gunduz, O.S., Glintborg, B., Østergaard, M., and Hetland, M.L.
Abstract: Item does not contain fulltext
Published: 2023

2. One-Third of European Patients With Axial Spondyloarthritis Reach Pain Remission With Routine Care Tumor Necrosis Factor Inhibitor Treatment.

Author: Ørnbjerg, L.M., Rugbjerg, K., Georgiadis, S., Rasmussen, S.H., Lindström, U., Pavelka, K., Yilmaz, N., Favalli, E.G., Nissen, M.J., Michelsen, B., Vieira-Sousa, E., Jones, G.T., Ionescu, R., Relas, H., Sanchez-Piedra, C., Tomšič, M., Geirsson, A.J., Horst-Bruinsma, I.E. van der, Askling, J., Loft, A.G., Nekvindova, L., Direskeneli, H., Iannone, F., Ciurea, A., Fagerli, K.M., Santos, M.J., Macfarlane, G.J., Codreanu, C., Eklund, K., Pombo-Suarez, M., Rotar, Z., Gudbjornsson, B., Rusman, T., Østergaard, M., Hetland, M.L., Ørnbjerg, L.M., Rugbjerg, K., Georgiadis, S., Rasmussen, S.H., Lindström, U., Pavelka, K., Yilmaz, N., Favalli, E.G., Nissen, M.J., Michelsen, B., Vieira-Sousa, E., Jones, G.T., Ionescu, R., Relas, H., Sanchez-Piedra, C., Tomšič, M., Geirsson, A.J., Horst-Bruinsma, I.E. van der, Askling, J., Loft, A.G., Nekvindova, L., Direskeneli, H., Iannone, F., Ciurea, A., Fagerli, K.M., Santos, M.J., Macfarlane, G.J., Codreanu, C., Eklund, K., Pombo-Suarez, M., Rotar, Z., Gudbjornsson, B., Rusman, T., Østergaard, M., and Hetland, M.L.
Abstract: 01 augustus 2023, Contains fulltext : 295991.pdf (Publisher’s version ) (Closed access), OBJECTIVE: To investigate the distribution of patient-reported outcomes (PROs) in patients with axial spondyloarthritis (axSpA) initiating a tumor necrosis factor inhibitor (TNFi), to assess the proportion reaching PRO "remission" across registries and treatment series, and to compare patients registered to fulfill the modified New York (mNY) criteria for ankylosing spondylitis (AS) vs patients with nonradiographic axSpA (nr-axSpA). METHODS: Fifteen European registries contributed PRO scores for pain, fatigue, patient global assessment (PtGA), Bath Ankylosing Spondylitis (AS) Disease Activity Index (BASDAI), Bath AS Functional Index (BASFI), and Health Assessment Questionnaire (HAQ) from 19,498 patients with axSpA. Changes in PROs and PRO remission rates (definitions: ≤ 20 mm for pain, fatigue, PtGA, BASDAI, and BASFI; ≤ 0.5 for HAQ) were calculated at 6, 12, and 24 months of treatment. RESULTS: Heterogeneity in baseline characteristics and outcomes between registries were observed. In pooled data, 6 months after the start of a first TNFi, pain score was reduced by approximately 60% (median at baseline/6/12/24 months: 65/25/20/20 mm) in patients on treatment. Similar patterns were observed for fatigue (68/32/30/25 mm), PtGA (66/29/21/20 mm), BASDAI (58/26/21/19 mm), BASFI (46/20/16/16 mm), and HAQ (0.8/0.4/0.2/0.2). Patients with AS (n = 3281) had a slightly better response than patients with nr-axSpA (n = 993). The Lund Efficacy Index (LUNDEX)-adjusted remission rates at 6 months for pain/fatigue/PtGA/BASDAI/BASFI/HAQ were 39%/30%/38%/34%/35%/48% for the AS cohort and 30%/21%/26%/24%/33%/47% for the nr-axSpA cohort. Better PRO responses were seen with a first TNFi compared to a second and third TNFi. CONCLUSION: Patients with axSpA starting a TNFi achieved high PRO remission rates, most pronounced in those fulfilling the mNY criteria and for the first TNFi.
Published: 2023

3. Systematic Review and Meta-analysis of Factors Influencing Survival Following Abdominal Aortic Aneurysm Repair

Author: Khashram, M., Williman, J.A., Hider, P.N., Jones, G.T., and Roake, J.A.
Published: 2016
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4. Prevalence of Abdominal Aortic Aneurysm (AAA) in a Population Undergoing Computed Tomography Colonography in Canterbury, New Zealand

Author: Khashram, M., Jones, G.T., and Roake, J.A.
Published: 2015
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5. Real-World Six- and Twelve-Month Drug Retention, Remission, and Response Rates of Secukinumab in 2,017 Patients With Psoriatic Arthritis in Thirteen European Countries

Author: Michelsen, B., Georgiadis, S., Giuseppe, D. Di, Loft, A.G., Nissen, M.J., Iannone, F., Pombo-Suarez, M., Mann, H., Rotar, Z., Eklund, K.K., Kvien, T.K., Santos, M.J., Gudbjornsson, B., Codreanu, C., Yilmaz, S., Wallman, J.K., Brahe, C.H., Möller, B., Favalli, E.G., Sánchez-Piedra, C., Nekvindova, L., Tomsic, M., Trokovic, N., Kristianslund, E.K., Santos, H. Dos, Löve, T.J., Ionescu, R., Pehlivan, Y., Jones, G.T., Horst-Bruinsma, I.E. van der, Ørnbjerg, L.M., Østergaard, M., Hetland, M.L., Michelsen, B., Georgiadis, S., Giuseppe, D. Di, Loft, A.G., Nissen, M.J., Iannone, F., Pombo-Suarez, M., Mann, H., Rotar, Z., Eklund, K.K., Kvien, T.K., Santos, M.J., Gudbjornsson, B., Codreanu, C., Yilmaz, S., Wallman, J.K., Brahe, C.H., Möller, B., Favalli, E.G., Sánchez-Piedra, C., Nekvindova, L., Tomsic, M., Trokovic, N., Kristianslund, E.K., Santos, H. Dos, Löve, T.J., Ionescu, R., Pehlivan, Y., Jones, G.T., Horst-Bruinsma, I.E. van der, Ørnbjerg, L.M., Østergaard, M., and Hetland, M.L.
Abstract: Item does not contain fulltext, OBJECTIVE: There is a lack of real-life studies on interleukin-17 (IL-17) inhibition in psoriatic arthritis (PsA). We assessed real-life 6- and 12-month effectiveness (i.e., retention, remission, low disease activity [LDA], and response rates) of the IL-17 inhibitor secukinumab in PsA patients overall and across 1) number of prior biologic/targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs), 2) years since diagnosis, and 3) European registries. METHODS: Thirteen quality registries in rheumatology participating in the European Spondyloarthritis Research Collaboration Network provided longitudinal, observational data collected as part of routine care for secondary use. Data were pooled and analyzed with Kaplan-Meier plots, log rank tests, Cox regression, and multiple linear and logistic regression analyses. RESULTS: A total of 2,017 PsA patients started treatment with secukinumab between 2015 and 2018. Overall secukinumab retention rates were 86% and 76% after 6 and 12 months, respectively. Crude (LUNDEX adjusted) 6-month remission/LDA (LDA including remission) rates for the 28-joint Disease Activity Index for Psoriatic Arthritis, the Disease Activity Score in 28 joints using the C-reactive protein level, and the Simplified Disease Activity Index (SDAI) were 13%/46% (11%/39%), 36%/55% (30%/46%), and 13%/56% (11%/47%), and 12-month rates were 11%/46% (7%/31%), 39%/56% (26%/38%), and 16%/62% (10%/41%), respectively. Clinical Disease Activity Index remission/LDA rates were similar to the SDAI rates. Six-month American College of Rheumatology 20%/50%/70% improvement criteria responses were 34%/19%/11% (29%/16%/9%); 12-month rates were 37%/21%/11% (24%/14%/7%). Secukinumab effectiveness was significantly better for b/tsDMARD-naive patients, similar across time since diagnosis (<2/2-4/>4 years), and varied significantly across the European registries. CONCLUSION: In this large real-world study on secukinumab treatment in PsA, 6- and 12-month effectiveness
Published: 2022

6. European bio-naïve spondyloarthritis patients initiating TNF inhibitor: time trends in baseline characteristics, treatment retention and response

Author: Christiansen, S.N., Ørnbjerg, L.M., Rasmussen, S.H., Loft, A.G., Askling, J., Iannone, F., Zavada, J., Michelsen, B., Nissen, M., Onen, F., Santos, M.J., Pombo-Suarez, M., Relas, H., Macfarlane, G.J., Tomsic, M., Codreanu, C., Gudbjornsson, B., Horst-Bruinsma, I.E. van der, Giuseppe, D. Di, Glintborg, B., Gremese, E., Pavelka, K., Kristianslund, E.K., Ciurea, A., Akkoc, N., Barcelos, A., Sánchez-Piedra, C., Peltomaa, R., Jones, G.T., Rotar, Z., Ionescu, R., Grondal, G., Sande, M.G. van de, Laas, K., Østergaard, M., Hetland, M.L., Christiansen, S.N., Ørnbjerg, L.M., Rasmussen, S.H., Loft, A.G., Askling, J., Iannone, F., Zavada, J., Michelsen, B., Nissen, M., Onen, F., Santos, M.J., Pombo-Suarez, M., Relas, H., Macfarlane, G.J., Tomsic, M., Codreanu, C., Gudbjornsson, B., Horst-Bruinsma, I.E. van der, Giuseppe, D. Di, Glintborg, B., Gremese, E., Pavelka, K., Kristianslund, E.K., Ciurea, A., Akkoc, N., Barcelos, A., Sánchez-Piedra, C., Peltomaa, R., Jones, G.T., Rotar, Z., Ionescu, R., Grondal, G., Sande, M.G. van de, Laas, K., Østergaard, M., and Hetland, M.L.
Abstract: Item does not contain fulltext, OBJECTIVES: To investigate time trends in baseline characteristics and retention, remission and response rates in bio-naïve axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) patients initiating TNF inhibitor (TNFi) treatment. METHODS: Prospectively collected data on bio-naïve axSpA and PsA patients from routine care in 15 European countries were pooled. Three cohorts were defined according to year of TNFi initiation: A (1999-2008), B (2009-2014) and C (2015-2018). Retention, remission and response rates were assessed at 6, 12 and 24 months. RESULTS: In total, 27 149 axSpA and 17 446 PsA patients were included. Cohort A patients had longer disease duration compared with B and C. In axSpA, cohort A had the largest proportion of male and HLA-B27 positive patients. In PsA, baseline disease activity was highest in cohort A. Retention rates in axSpA/PsA were highest in cohort A and differed only slightly between B and C. For all cohorts, disease activity decreased markedly from 0 to 6 months. In axSpA, disease activity at 24 months was highest in cohort A, where also remission and response rates were lowest. In PsA, remission rates at 6 and 12 months tended to be lowest in cohort A. Response rates were at all time points comparable across cohorts, and less between-cohort disease activity differences were seen at 24 months. CONCLUSION: Our findings indicate that over the past decades, clinicians have implemented more aggressive treatment strategies in spondyloarthritis. This was illustrated by shorter disease duration at treatment initiation, decreased retention rates and higher remission rates during recent years.
Published: 2022

7. Chronic pelvic pain in women of reproductive and post‐reproductive age: a population‐based study

Author: Ayorinde, A.A., Bhattacharya, S., Druce, K.L., Jones, G.T., and Macfarlane, G.J.
Published: 2017
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8. Predictors of abdominal pain in schoolchildren: a 4-year population-based prospective study

Author: El-Metwally, A., Halder, S., Thompson, D., Macfarlane, G.J., and Jones, G.T.
Subjects: Abdominal pain in children -- Diagnosis, Abdominal pain in children -- Psychological aspects, Abdominal pain in children -- Research, Elementary school students -- Health aspects, Elementary school students -- Surveys, Risk factors (Health) -- Research, Stature, Tall -- Health aspects
Published: 2007

9. Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors

Author: Bakker, M.K., Spek, R.A.A. van der, Rheenen, W. van, Morel, S., Bourcier, R., Hostettler, I.C., Alg, V.S., Eijk, Kristel R. van, Koido, M., Akiyama, M., Terao, C., Matsuda, K., Walters, R.G., Lin, K., Li, L, Millwood, I.Y., Chen, Z., Rouleau, G.A., et al., Zhou, S., Rannikmäe, K., Sudlow, C.L., Houlden, H., Berg, L.H. van den, Dina, C., Naggara, O., Gentric, J.C., Shotar, E., Eugène, F., Desal, H., Winsvold, B.S., Børte, S., Johnsen, M.B., Brumpton, B.M., Sandvei, M.S., Willer, C.J., Hveem, K., Zwart, Jacob A., Verschuren, W.M., Friedrich, C.M., Hirsch, S., Schilling, S., Dauvillier, J., Martin, O., Jones, G.T., Bown, M.J., Ko, N.U., Kim, H., Coleman, J.R.I., Breen, G., Zaroff, J.G., Klijn, C.J.M., Malik, R., Dichgans, M., Sargurupremraj, M., Tatlisumak, T., Amouyel, P., Debette, S., Rinkel, G.J., Worrall, B.B., Pera, J., Slowik, A., Gaál-Paavola, E.I., Niemelä, M., Jääskeläinen, J.E., Fraunberg, M. von Und Zu, Lindgren, A., Broderick, J.P., Werring, D.J., Woo, D., Redon, R., Bijlenga, P., Kamatani, Y., Veldink, J.H., Ruigrok, Y.M., Bakker, M.K., Spek, R.A.A. van der, Rheenen, W. van, Morel, S., Bourcier, R., Hostettler, I.C., Alg, V.S., Eijk, Kristel R. van, Koido, M., Akiyama, M., Terao, C., Matsuda, K., Walters, R.G., Lin, K., Li, L, Millwood, I.Y., Chen, Z., Rouleau, G.A., et al., Zhou, S., Rannikmäe, K., Sudlow, C.L., Houlden, H., Berg, L.H. van den, Dina, C., Naggara, O., Gentric, J.C., Shotar, E., Eugène, F., Desal, H., Winsvold, B.S., Børte, S., Johnsen, M.B., Brumpton, B.M., Sandvei, M.S., Willer, C.J., Hveem, K., Zwart, Jacob A., Verschuren, W.M., Friedrich, C.M., Hirsch, S., Schilling, S., Dauvillier, J., Martin, O., Jones, G.T., Bown, M.J., Ko, N.U., Kim, H., Coleman, J.R.I., Breen, G., Zaroff, J.G., Klijn, C.J.M., Malik, R., Dichgans, M., Sargurupremraj, M., Tatlisumak, T., Amouyel, P., Debette, S., Rinkel, G.J., Worrall, B.B., Pera, J., Slowik, A., Gaál-Paavola, E.I., Niemelä, M., Jääskeläinen, J.E., Fraunberg, M. von Und Zu, Lindgren, A., Broderick, J.P., Werring, D.J., Woo, D., Redon, R., Bijlenga, P., Kamatani, Y., Veldink, J.H., and Ruigrok, Y.M.
Abstract: Contains fulltext : 229738.pdf (Publisher’s version ) (Closed access), Rupture of an intracranial aneurysm leads to subarachnoid hemorrhage, a severe type of stroke. To discover new risk loci and the genetic architecture of intracranial aneurysms, we performed a cross-ancestry, genome-wide association study in 10,754 cases and 306,882 controls of European and East Asian ancestry. We discovered 17 risk loci, 11 of which are new. We reveal a polygenic architecture and explain over half of the disease heritability. We show a high genetic correlation between ruptured and unruptured intracranial aneurysms. We also find a suggestive role for endothelial cells by using gene mapping and heritability enrichment. Drug-target enrichment shows pleiotropy between intracranial aneurysms and antiepileptic and sex hormone drugs, providing insights into intracranial aneurysm pathophysiology. Finally, genetic risks for smoking and high blood pressure, the two main clinical risk factors, play important roles in intracranial aneurysm risk, and drive most of the genetic correlation between intracranial aneurysms and other cerebrovascular traits.
Published: 2020

10. Epidemiology of low back pain in children and adolescents

Author: Jones, G.T. and Macfarlane, G.J.
Subjects: Low back pain -- Development and progression, Low back pain -- Causes of, Lifting and carrying -- Complications and side effects, Emotional problems of children -- Complications and side effects
Published: 2005

11. Low back pain in schoolchildren: the role of mechanical and psychosocial factors. (Original Article)

Author: Watson, K.D., Papageorgiou, A.C., Jones, G.T., Taylor, S., Symmons, D.P.M., Silman, A.J., and Macfarlane, G.J.
Subjects: Children -- Health aspects, Backache -- Risk factors, Family and marriage, Health, Risk factors, Health aspects
Abstract: Background: Low back pain (LBP) in schoolchildren with no apparent clinical cause is known to be a common problem, but considerably less is understood regarding the aetiology of such pain. [...]
Published: 2003

12. The Methylenetetrahydrofolate Reductase C677T Polymorphism Does Not Associate with Susceptibility to Abdominal Aortic Aneurysm

Author: Jones, G.T., Harris, E.L., Phillips, L.V., and van Rij, A.M.
Published: 2005
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13. The influence of socioeconomic status on the reporting of regional and widespread musculoskeletal pain: results from the 1958 British Birth Cohort Study

Author: Macfarlane, G.J., Norrie, G., Atherton, K., Power, C., and Jones, G.T.
Subjects: Low back pain -- Distribution, Low back pain -- Demographic aspects, Low back pain -- Research, Social classes -- Influence, Social classes -- Health aspects, Social classes -- Research, Arthralgia -- Influence, Arthralgia -- Health aspects, Arthralgia -- Research, Company distribution practices, Health
Published: 2009

14. Hyperon yields in Pb-Pb collisions from the NA57 experiment

Author: Antinori, F., primary, Badalà, A., additional, Barbera, R., additional, Belogianni, A., additional, Bhasin, A., additional, Bloodworth, I.J., additional, Bruno, G.E., additional, Bull, S.A., additional, Caliandro, R., additional, Campbell, M., additional, Carena, W., additional, Carrer, N., additional, Clarke, R.F., additional, Dainese, A., additional, de Haas, A.R., additional, de Rijke, RC., additional, Di Bari, D., additional, Di Liberto, S., additional, Divia, R., additional, Elia, D., additional, Evans, D., additional, Fanebust, K., additional, Fayazzadeh, F., additional, Fedoriŝin, J., additional, Feofilov, G.A., additional, Fini, R.A., additional, Ganoti, P., additional, Ghidini, B., additional, Grella, G., additional, Helstrup, H., additional, Henriquez, M., additional, Holme, A.K., additional, Jacholkowski, A., additional, Jones, G.T., additional, Jovanović, P., additional, Jusko, A., additional, Kammermans, R., additional, Kinson, J.B., additional, Knudson, K., additional, Kolozhvari, A.A., additional, Kondratiev, V., additional, Králik, I., additional, Kravĉáková, A., additional, Kuijer, P., additional, Lenti, V., additional, Lietava, R., additional, Løvhøiden, G., additional, Manzari, V., additional, Martinská, G., additional, Mazzoni, M.A., additional, Meddi, F., additional, Michalon, A., additional, Morando, M., additional, Nappi, E., additional, Navach, F., additional, Norman, P.I., additional, Palmeri, A., additional, Pappalardo, G.S., additional, Pastirĉák, B., additional, Pišút, J., additional, Pišútová, N., additional, Posa, F., additional, Quercigh, E., additional, Riggi, F., additional, Röhrich, D., additional, Romano, G., additional, Šafařík, K., additional, Šándor, L., additional, Schillings, E., additional, Segato, G., additional, Senè, R., additional, Senè, M., additional, Snoeyes, W., additional, Soramel, F., additional, Spyropoulou-Stassinaki, M., additional, Staroba, P., additional, Toulina, T.A., additional, Turrisi, R., additional, Tveter, T.S., additional, Urbán, J., additional, Valiev, F.F., additional, van den Brink, A., additional, van den Ven, P., additional, Vande Vyvre, P., additional, van Eijndhoven, N., additional, van Hunen, J., additional, Vascotto, A., additional, Vik, T., additional, Villalobos-Baillie, O., additional, Vinogradov, L., additional, Virgili, T., additional, Votruba, M.F., additional, Vrláková, J., additional, and Závada, P., additional
Published: 2003
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15. Hyperon production in lead-lead interactions at 40 and 160 A GeV/c

Author: Antinori, F., Bacon, P.A., Badalà, A., Barbera, R., Belogianni, A., Bhasin, A., Bloodworth, I.J., Bombara, M., Bruno, G.E., Bull, S.A., Caliandro, R., Campbell, M., Carena, W., Carrer, N., Clarke, R.F., Dainese, A., de Haas, A.P., de Rijke, P.C., Bari, D. Di, Liberto, S. Di, Divià, R., Elia, D., Evans, D., Fanebust, K., Feofilov, G.A., Fini, R.A., Ganoti, P., Ghidini, B., Grella, G., Helstrup, H., Holme, A.K., Jacholkowski, A., Jones, G.T., Jovanovic, P., Jusko, A., Kamermans, R., Kinson, J.B., Knudson, K., Kolozhvari, A.A., Kondratiev, V., Králik, I., Kravčáková, A., Kuijer, P., Lenti, V., Lietava, R., Løvhøiden, G., Manzari, V., Martinská, G., Mazzoni, M.A., Meddi, F., Michalon, A., Morando, M., Nappi, E., Navach, F., Norman, P.I., Palmeri, A., Pappalardo, G.S., Pastirčák, B., Pišút, J., Pišútova, N., Posa, F., Quercigh, E., Riggi, F., Röhrich, D., Romano, G., Šafařík, K., Šándor, L., Schillings, E., Segato, G., Sené, M., Sené, R., Snoeys, W., Soramel, F., Spyropoulou-Stassinaki, M., Staroba, P., Toulina, T.A., Turrisi, R., Tveter, T.S., Urbán, J., Valiev, F., van den Brink, A., van de Ven, P., Vyvre, P. Vande, van Eijndhoven, N., van Hunen, J., Vascotto, A., Vik, T., Baillie, O. Villalobos, Vinogradov, L., Virgili, T., Votruba, M.F., Vrláková, J., and Závada, P.
Published: 2004
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16. Predictors of persistent neck pain after whiplash injury

Author: Atherton, K., Wiles, N.J., Lecky, F.E., Hawes, S.J., Silman, A.J., Macfarlane, G.J., and Jones, G.T.
Subjects: Whiplash injuries -- Complications and side effects, Neck pain -- Risk factors, Neck pain -- Research, Traffic accidents -- Physiological aspects, Traffic accidents -- Research, Health
Published: 2006

17. Hyperon production in 158 and 40 A GeV/ c Pb [sbnd]Pb and p-Be collisions from the NA57 experiment

Author: Antinori, F., Bacon, P.A., Badala`, A., Barbera, R., Belogianni, A., Bhasin, A., Bloodworth, I.J., Bombara, M., Bruno, G.E., Bull, S.A., Caliandro, R., Campbell, M., Carena, W., Carrer, N., Clarke, R.F., Dainese, A., de Haas, A.P., de Rijke, P.C., Di Bari, D., Di Liberto, S., Divia`, R., Elia, D., Evans, D., Fanebust, K., Feofilov, G.A., Fini, R.A., Ganoti, P., Ghidini, B., Grella, G., Helstrup, H., Holme, A.K., Jacholkowski, A., Jones, G.T., Jovanovic, P., Jusko, A., Kamermans, R., Kinson, J.B., Knudson, K., Kolozhvari, A.A., Kondratiev, V., Kra´lik, I., Kravcˇa´kova´, A., Kuijer, P., Lenti, V., Lietava, R., Løvhøiden, G., Manzari, V., Martinska´, G., Mazzoni, M.A., Meddi, F., Michalon, A., Morando, M., Nappi, E., Navach, F., Norman, P.I., Palmeri, A., Pappalardo, G.S., Pastircˇa´k, B., Pisˇu´t, J., Posa, F., Quercigh, E., Riggi, F., Ro¨hrich, D., Romano, G., Sˇafarˇi´k, K., Sˇandor, L., Schillings, E., Segato, G., Sene´, M., Sene´, R., Snoeys, W., Soramel, F., Spyropoulou-Stassinaki, M., Staroba, P., Toulina, T.A., Turrisi, R., Tveter, T.S., Urba´n, J., Valiev, F., van den Brink, A., van de Ven, P., Vande Vyvre, P., van Eijndhoven, N., van Hunen, J., Vascotto, A., Vik, T., Villalobos-Baillie, O., Vinogradov, L., Virgili, T., Votruba, M.F., Vrla´kova´, J., and Za´vada, P.
Published: 2004
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18. A variant of the castor zinc finger 1 (CASZ1) gene is differentially associated with the clinical classification of chronic venous disease

Author: Jones, G.T. (Gregory), Marsman, J. (Judith), Pardo Cortes, L.M. (Luba), Nijsten, T.E.C. (Tamar), Maeseneer, M.G.R. (Marianne) de, Phillips, V. (Vicky), Lynch-Sutherland, C. (Chi), Horsfield, J. (Julia), Krysa, J. (Jolanda), Rij, A.M. (Andre) van, Jones, G.T. (Gregory), Marsman, J. (Judith), Pardo Cortes, L.M. (Luba), Nijsten, T.E.C. (Tamar), Maeseneer, M.G.R. (Marianne) de, Phillips, V. (Vicky), Lynch-Sutherland, C. (Chi), Horsfield, J. (Julia), Krysa, J. (Jolanda), and Rij, A.M. (Andre) van
Abstract: Recent reports have suggested a reproducible association between the rs11121615 SNP, located within an intron of the castor zinc finger 1 (CASZ1) gene, and varicose veins. This study aimed to determine if this variant is also differentially associated with the various clinical classifications of chronic venous disease (CVD). The rs11121615 SNP was genotyped in two independent cohorts from New Zealand (n = 1876 controls /1606 CVD cases) and the Netherlands (n = 1626/2966). Participants were clinically assessed using well-established CVD criteria. The association between the rs11121615 C-allele and varicose veins was validated in both cohorts. This was strongest in those with higher clinical severity classes and was not significant in those with non-varicose vein CVD. Functional analysis of the rs11121615 variant demonstrated that the risk allele was associated with increased enhancer activity. This study demonstrates that the CASZ1 gene associated C-allele of rs11121615 has a significant, reproducible, association with CVD (CEAP C ≥ 2 meta-odds ratio 1.31, 95% CI 1.27-1.34, P = 1 × 10-98, PHet = 0.25), but not with non-varicose vein (CEAP C1, telangiectasia or reticular veins) forms of venous disease. The effect size of this association therefore appears to be susceptible to influence by phenotypic heterogeneity, particularly if a cohort includes a large number of cases with lower severity CVD.
Published: 2019
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19. Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

Author: Jones, G.T., Tromp, G., Kuivaniemi, H., Gretarsdottir, S., Baas, A.F., Giusti, B., Strauss, E., Hof, F.N. van 't, Webb, T.R., Erdman, R., Ritchie, M.D., Elmore, J.R., Verma, A., Pendergrass, S., Kullo, I.J., Ye, Z., Peissig, P.L., Gottesman, O., Verma, S.S., Malinowski, J., Rasmussen-Torvik, L.J., Borthwick, K.M., Smelser, D.T., Crosslin, D.R., Andrade, M. de, Ryer, E.J., McCarty, C.A., Bottinger, E.P., Pacheco, J.A., Crawford, D.C., Carrell, D.S., Gerhard, G.S., Franklin, D.P., Carey, D.J., Phillips, V.L., Williams, M.J., Wei, W., Blair, R., Hill, A.A., Vasudevan, T.M., Lewis, D.R., Thomson, I.A., Krysa, J., Hill, G.B., Roake, J., Merriman, T.R., Oszkinis, G., Galora, S., Saracini, C., Abbate, R., Pulli, R., Pratesi, C., Saratzis, A., Verissimo, A.R., Bumpstead, S., Badger, S.A., Clough, R.E., Cockerill, G., Hafez, H., Scott, D.J., Futers, T.S., Romaine, S.P., Bridge, K., Griffin, K.J., Bailey, M.A., Smith, A., Thompson, M.M., Bockxmeer, F.M. van, Matthiasson, S.E., Thorleifsson, G., Thorsteinsdottir, U., Blankensteijn, J.D., Teijink, J.A., Wijmenga, C., Graaf, J. de, Kiemeney, L.A.L.M., Lindholt, J.S., Hughes, A., Bradley, D.T., Stirrups, K., Golledge, J., Norman, P.E., Powell, J.T., Humphries, S.E., Hamby, S.E., Goodall, A.H., Nelson, C.P., Sakalihasan, N., Courtois, A., Ferrell, R.E., Eriksson, P., Folkersen, L., Franco-Cereceda, A., Eicher, J.D., Johnson, A.D., Betsholtz, C., Ruusalepp, A., Franzen, O., Schadt, E.E., and Bjorkegren, J.L.
Subjects: Urological cancers Radboud Institute for Health Sciences [Radboudumc 15], Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], cardiovascular system, cardiovascular diseases
Abstract: Contains fulltext : 169744.pdf (Publisher’s version ) (Open Access) RATIONALE: Abdominal aortic aneurysm (AAA) is a complex disease with both genetic and environmental risk factors. Together, 6 previously identified risk loci only explain a small proportion of the heritability of AAA. OBJECTIVE: To identify additional AAA risk loci using data from all available genome-wide association studies. METHODS AND RESULTS: Through a meta-analysis of 6 genome-wide association study data sets and a validation study totaling 10 204 cases and 107 766 controls, we identified 4 new AAA risk loci: 1q32.3 (SMYD2), 13q12.11 (LINC00540), 20q13.12 (near PCIF1/MMP9/ZNF335), and 21q22.2 (ERG). In various database searches, we observed no new associations between the lead AAA single nucleotide polymorphisms and coronary artery disease, blood pressure, lipids, or diabetes mellitus. Network analyses identified ERG, IL6R, and LDLR as modifiers of MMP9, with a direct interaction between ERG and MMP9. CONCLUSIONS: The 4 new risk loci for AAA seem to be specific for AAA compared with other cardiovascular diseases and related traits suggesting that traditional cardiovascular risk factor management may only have limited value in preventing the progression of aneurysmal disease.
Published: 2017

20. Enhancement of strange and multi-strange baryons in central Pb−Pb interactions at 158 GeV/ c per nucleon

Author: Antinori, F., Bakke, H., Beusch, W., Bloodworth, I.J., Caliandro, R., Carrer, N., Di Bari, D., Di Liberto, S., Elia, D., Evans, D., Fanebust, K., Fini, R.A., Ftáčnik, J., Ghidini, B., Grella, G., Helstrup, H., Holme, A.K., Huss, D., Jacholkowski, A., Jones, G.T., Kinson, J.B., Knudson, K., Králik, I., Lenti, V., Lietava, R., Loconsole, R.A., Løvhøiden, G., Manzari, V., Mazzoni, M.A., Meddi, F., Michalon, A., Michalon-Mentzer, M.E., Morando, M., Norman, P.I., Pastirčák, B., Quercigh, E., Romano, G., Šafařík, K., Šándor, L., Segato, G., Staroba, P., Thompson, M., Thorsteinsen, T.F., Torrieri, G.D., Tveter, T.S., Urbán, J., Villalobos Baillie, O., Virgili, T., Votruba, M.F., and Závada, P.
Published: 2000
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21. Does physical trauma lead to an increase in the risk of new onset widespread pain?

Author: Wynne-Jones, G., Macfarlane, G.J., Silman, A.J., and Jones, G.T.
Subjects: Pain -- Risk factors, Crash injuries -- Physiological aspects, Crash injury research -- Reports, Health
Published: 2006

22. Silicon pixel detectors for tracking in NA57

Author: Manzari, V., Antinori, F., Badalà, A., Barbera, R., Beker, H., Bloodworth, I.J., Botje, M., Caliandro, R., Campbell, M., Cantatore, E., Carena, W., Carrer, N., de Haas, A.P., Di Bari, D., Di Liberto, S., Divia, R., Elia, D., Evans, D., Fanebust, K., Fedorisin, J., Feofilov, G.A., Fini, R.A., Ftáčnik, J., Ghidini, B., Grella, G., Gulino, M., Helstrup, H., Holme, A.K., Jacholkowski, A., Jones, G.T., Jovanovic, P., Jusko, A., Kamermans, R., Kinson, J.B., Klempt, W., Knudson, K., Kocper, B., Kolojvari, A.A., Králik, I., Kuijer, P., Lenti, V., Lietava, R., Løvhøiden, G., Lupták, M., Mazzoni, M.A., Martinska, G., Meddi, F., Michalon, A., Michalon-Mentzer, M.E., Morando, M., Nappi, E., Navach, F., Norman, P.I., Palmeri, A., Pappalardo, G.S., Pastirčák, B., Pellegrini, F., Píška, K., Pisut, J., Pisutova, N., Posa, F., Quercigh, E., Riggi, F., Romano, G., Šafařík, K., Šándor, L., schillings, E., Segato, G., Sené, M., Sené, R., Snoeys, W., Staroba, P., Stolyarov, O.I., Thompson, M., Thorsteinsen, T.F., Tomasicchio, G., Torrieri, G.D., Tsimbal, F.A., Tulina, T.A., Tveter, T.S., Urbán, J., Valiev, F.F., van den Brink, A., van de Ven, P., Vande Vyvre, P., van Eijndhoven, N., Vannucci, L., Vascotto, A., Villalobos Baillie, O., Vinogradov, I., Virgili, T., Votruba, M.F., Vrlakova, J., and Závada, P.
Published: 1999
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23. Transverse mass spectra of strange and multiply—strange particles in Pb—Pb collisions at 158 A GeV/ c

Author: Antinori, F., Bakke, H., Beusch, W., Bloodworth, I.J., Caliandro, R., Carrer, N., Di Bari, D., Di Liberto, S., Elia, D., Evans, D., Fanebust, K., Fini, R.A., Ftáčnik, J., Ghidini, B., Grella, G., Helstrup, H., Holme, A.K., Huss, D., Jacholkowski, A., Jones, G.T., Kinson, J.B., Knudson, K., Králik, I., Lenti, V., Lietava, R., Loconsole, R.A., Løvhøiden, G., Manzari, V., Mazzoni, M.A., Meddi, F., Michalon, A., Michalon-Mentzer, M.E., Morando, M., Norman, P.I., Pastirčak, B., Quercigh, E., Romano, G., Šafařík, K., Šándor, L., Segato, G., Staroba, P., Thompson, M., Thorsteinsen, T.F., Torrieri, G.D., Tveter, T.S., Urbán, J., Villalobos Baillie, O., Virgili, T., Votruba, M.F., and Závada, P.
Published: 1999
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24. Hyperon and negative particle production at central rapidity in proton-Beryllium interactions at 158 GeV/ c

Author: Antinori, F., Bakke, H., Beusch, W., Bloodworth, I.J., Caliandro, R., Carrer, N., Di Bari, D., Di Liberto, S., Elia, D., Evans, D., Fanebust, K., Fini, R.A., Ftáčnik, J., Ghidini, B., Grella, G., Helstrup, H., Holme, A.K., Huss, D., Jacholkowski, A., Jones, G.T., Kinson, J.B., Knudson, K., Králik, I., Lenti, V., Lietava, R., Loconsole, R.A., Løvhøiden, G., Manzari, V., Mazzoni, M.A., Meddi, F., Michalon, A., Michalon-Mentzer, M.E., Morando, M., Norman, P.I., Pastirčák, B., Quercigh, E., Romano, G., Šafařík, K., Šándor, L., Segato, G., Staroba, P., Thompson, M., Thorsteinsen, T.F., Torrieri, G.D., Tveter, T.S., Urbán, J., Villalobos Baillie, O., Virgili, T., Votruba, M.F., and Závada, P.
Published: 1999
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25. Determination of the number of wounded nucleons in Pb+Pb collisions at 158 A GeV/ c

Author: Antinori, F., Badalà, A., Bakke, H., Barbera, R., Beker, H., Beusch, W., Bloodworth, I.J., Botje, M., Caliandro, R., Campbell, M., Cantatore, E., Carena, W., Carrer, N., de Haas, A.P., Di Bari, D., Di Liberto, S., Divia, R., Elia, D., Evans, D., Fanebust, K., Fedorisin, J., Feofilov, G.A., Fini, R.A., Ftáčnik, J., Ghidini, B., Grella, G., Gulino, M., Helstrup, H., Holme, A.K., Huss, D., Jacholkowski, A., Jones, G.T., Jovanovic, P., Jusko, A., Kamermans, R., Kinson, J.B., Klempt, W., Knudson, K., Kocper, B., Kolojvari, A.A., Králik, I., Kuijer, P., Lenti, V., Lietava, R., Loconsole, R.A., Løvhøiden, G., Lupták, M., Manzari, V., Mazzoni, M.A., Martinska, G., Meddi, F., Michalon, A., Michalon-Mentzer, M.E., Morando, M., Nappi, E., Navach, F., Norman, P.I., Palmeri, A., Pappalardo, G.S., Pastirčák, B., Pellegrini, F., Píška, K., Pisut, J., Pisutova, N., Posa, F., Quercigh, E., Riggi, F., Romano, G., Šafařík, K., Šándor, L., Schillings, E., Segato, G., Sené, M., Sené, R., Snoeys, W., Staroba, P., Stolyarov, O.I., Thompson, M., Thorsteinsen, T.F., Tomasicchio, G., Torrieri, G.D., Tsimbal, F.A., Tulina, T.A., Tveter, T.S., Urbán, J., Valiev, F.F., van den Brink, A., van de Ven, P., Vande Vyvre, P., van Eijndhoven, N., Vannucci, L., Vascotto, A., Baillie, O.Villalobos, Vinogradov, I., Virgili, T., Votruba, M.F., Vrlakova, J., and Závada, P.
Published: 1999
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26. Production of strange and multistrange hadrons in nucleus—nucleus collisions at the SPS

Author: Antinori, F., Bakke, H., Beusch, W., Bloodworth, I.J., Caliandro, R., Carrer, N., Di Bari, D., Di Liberto, S., Elia, D., Evans, D., Fanebust, K., Fini, R.A., Ftáčnik, J., Ghidini, B., Grella, G., Helstrup, H., Holme, A.K., Huss, D., Jacholkowski, A., Jones, G.T., Kinson, J.B., Knudson, K., Králik, I., Lenti, V., Lietava, R., Loconsole, R.A., Løvhøiden, G., Manzari, V., Mazzoni, M.A., Meddi, F., Michalon, A., Michalon-Mentzer, M.E., Morando, M., Norman, P.I., Pastirčák, B., Quercigh, E., Romano, G., Šafařík, K., Šándor, L., Segato, G., Staroba, P., Thompson, M., Thorsteinsen, T.F., Torrieri, G.D., Tveter, T.S., Urbán, J., Villalobos Baillie, O., Virgili, T., Votruba, M.F., and Závada, P.
Published: 1999
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27. A partial wave analysis of the centrally produced π0π0 system in pp interactions at 450 GeV/c

Author: Barberis, D., Beusch, W., Binon, F.G., Blick, A.M., Close, F.E., Danielsen, K.M., Dolgopolov, A.V., Donskov, S.V., Earl, B.C., Evans, D., French, B.R., Hino, T., Inaba, S., Inyakin, A.V., Ishida, T., Jacholkowski, A., Jacobsen, T., Jones, G.T., Khaustov, G.V., Kinashi, T., Kinson, J.B., Kirk, A., Klempt, W., Kolosov, V., Kondashov, A.A., Lednev, A.A., Lenti, V., Maljukov, S., Martinengo, P., Minashvili, I., Nakagawa, T., Norman, K.L., Peigneux, J.P., Polovnikov, S.A., Polyakov, V.A., Romanovsky, V., Rotscheidt, H., Rumyantsev, V., Russakovich, N., Samoylenko, V.D., Semenov, A., Sené, M., Sené, R., Shagin, P.M., Shimizu, H., Singovsky, A.V., Sobol, A., Solovjev, A., Stassinaki, M., Stroot, J.P., Sugonyaev, V.P., Takamatsu, K., Tchlatchidze, G., Tsuru, T., Venables, M., Villalobos Baillie, O., Votruba, M.F., and Yasu, Y.
Published: 1999
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28. A partial wave analysis of the centrally produced K+K− and KS0KS0 systems in pp interactions at 450 GeV/c and new information on the spin of the fJ(1710)

Author: Barberis, D., Beusch, W., Binon, F.G., Blick, A.M., Close, F.E., Danielsen, K.M., Dolgopolov, A.V., Donskov, S.V., Earl, B.C., Evans, D., French, B.R., Hino, T., Inaba, S., Inyakin, A.V., Ishida, T., Jacholkowski, A., Jacobsen, T., Jones, G.T., Khaustov, G.V., Kinashi, T., Kinson, J.B., Kirk, A., Klempt, W., Kolosov, V., Kondashov, A.A., Lednev, A.A., Lenti, V., Maljukov, S., Martinengo, P., Minashvili, I., Nakagawa, T., Norman, K.L., Peigneux, J.P., Polovnikov, S.A., Polyakov, V.A., Romanovsky, V., Rotscheidt, H., Rumyantsev, V., Russakovich, N., Samoylenko, V.D., Semenov, A., Sené, M., Sené, R., Shagin, P.M., Shimizu, H., Singovsky, A.V., Sobol, A., Solovjev, A., Stassinaki, M., Stroot, J.P., Sugonyaev, V.P., Takamatsu, K., Tchlatchidze, G., Tsuru, T., Venables, M., Villalobos Baillie, O., Votruba, M.F., and Yasu, Y.
Published: 1999
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29. Strangeness enhancement at mid-rapidity in Pb–Pb collisions at 158 A GeV/ c

Author: Andersen, E., Antinori, F., Armenise, N., Bakke, H., Bán, J., Barberis, D., Beker, H., Beusch, W., Bloodworth, I.J., Böhm, J., Caliandro, R., Campbell, M., Cantatore, E., Carrer, N., Catanesi, M.G., Chesi, E., Dameri, M., Darbo, G., Diaczek, A., Di Bari, D., Di Liberto, S., Earl, B.C., Elia, D., Evans, D., Fanebust, K., Fini, R.A., Fontaine, J.C., Ftáčnik, J., Ghidini, B., Grella, G., Guida, M., Heijne, E.H.M., Helstrup, H., Holme, A.K., Huss, D., Jacholkowski, A., Jones, G.T., Jovanovic, P., Jusko, A., Kachelhoffer, T., Kinson, J.B., Kirk, A., Klempt, W., Knudsen, B.T.H., Knudson, K., Králik, I., Lenti, V., Lietava, R., Loconsole, R.A., Løvhøiden, G., Lupták, M., Mack, V., Manzari, V., Martinengo, P., Mazzoni, M.A., Meddi, F., Michalon, A., Michalon-Mentzer, M.E., Middelkamp, P., Morando, M., Muciaccia, M.T., Nappi, E., Navach, F., Norman, P.I., Osculati, B., Pastirčák, B., Pellegrini, F., Pı́ška, K., Posa, F., Quercigh, E., Ricci, R.A., Romano, G., Rosa, G., Rossi, L., Rotscheidt, H., Šafařı́k, K., Saladino, S., Salvo, C., Šándor, L., Segato, G., Sené, M., Sené, R., Simone, S., Snoeys, W., Staroba, P., Szafran, S., Thompson, M., Thorsteinsen, T.F., Tomasicchio, G., Torrieri, G.D., Tveter, T.S., Urbán, J., Venables, M., Villalobos Baillie, O., Virgili, T., Volte, A., Votruba, M.F., and Závada, P.
Published: 1999
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30. A study of the centrally produced baryon-antibaryon systems in pp interactions at 450 GeV/c

Author: Barberis, D, Beusch, W, Binon, F.G, Blick, A.M, Close, F.E, Danielsen, K.M, Dolgopolov, A.V, Donskov, S.V, Earl, B.C, Evans, D, French, B.R, Hino, T, Inaba, S, Inyakin, A.V, Ishida, T, Jacholkowski, A, Jacobsen, T, Jones, G.T, Khaustov, G.V, Kinashi, T, Kinson, J.B, Kirk, A, Klempt, W, Kolosov, V, Kondashov, A.A, Lednev, A.A, Lenti, V, Maljukov, S, Martinengo, P, Minashvili, I, Nakagawa, T, Norman, K.L, Peigneux, J.P, Polovnikov, S.A, Polyakov, V.A, Romanovsky, V, Rotscheidt, H, Rumyantsev, V, Russakovich, N, Samoylenko, V.D, Semenov, A, Sené, M, Sené, R, Shagin, P.M, Shimizu, H, Singovsky, A.V, Sobol, A, Solovjev, A, Stassinaki, M, Stroot, J.P, Sugonyaev, V.P, Takamatsu, K, Tchlatchidze, G, Tsuru, T, Venables, M, Villalobos Baillie, O, Votruba, M.F, and Yasu, Y
Published: 1999
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31. A measurement of the holographic minimum-observable beam branching ratio in the FERMILAB 15-ft bubble chamber

Author: Aderholz, M., Aggarwal, M.M., Akbari, H., Allport, P.P., Badyal, S.K., Ballagh, H.C., Barth, M., Baton, J.P., Bingham, H.H., Bjelkhagen, H., Brucker, E.B., Burnstein, R.A., Campbell, J.R., Cence, R.J., Chatterjee, T.K., Clayton, E.F., Corrigan, G., Coutures, C., DeProspo, D., Devanand, De Wolf, E.A., Faulkner, P.J.W., Foeth, H., Fretter, W.B., Geissler, K., Gupta, V.K., Hanlon, J., Harigel, G.G., Harris, F.A., Hawkins, J., Jabiol, M.A., Jacques, P., Jones, G.T., Jones, M.D., Kafka, T., Kalelkar, M., Kasper, P., Kohli, J.M., Koller, E.L., Krawiec, R.J., Lauko, M., Lys, J.E., Marage, P., Milburn, R.H., Miller, D.B., Mittra, I.S., Mobayyen, M.M., Moreels, J., Morrison, D.R.O., Myatt, G., Naon, R., Napier, A., Naylor, P., Neveu, M., Passmore, D., Peters, M.W., Peterson, V.Z., Plano, R., Rao, N.K., Rubin, H.A., Sacton, J., Sambyal, S.S., Schmitz, N., Schneps, J., Sekulin, R.L., Sewell, S., Singh, J.B., Smart, W., Stamer, P., Varvell, K.E., Verluyten, L., Voyvodic, L., Wachsmuth, H., Wainstein, S., Williams, W., Willocq, S., and Yost, G.P.
Published: 1999
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32. Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study

Author: Haycock, P.C., Burgess, S., Nounu, A., Zheng, J., Okoli, G.N., Bowden, J., Wade, K.H., Timpson, N.J., Evans, D.M., Willeit, P., Aviv, A., Gaunt, T.R., Hemani, G., Mangino, M., Ellis, H.P., Kurian, K.M., Pooley, K.A., Eeles, R.A., Lee, J.E., Fang, S., Chen, W.V., Law, M.H., Bowdler, L.M., Iles, M.M., Yang, Q., Worrall, B.B., Markus, H.S., Hung, R.J., Amos, C.I., Spurdle, A.B., Thompson, D.J., O'Mara, T.A., Wolpin, B., Amundadottir, L., Stolzenberg-Solomon, R., Trichopoulou, A., Onland-Moret, N.C., Lund, E., Duell, E.J., Canzian, F., Severi, G., Overvad, K., Gunter, M.J., Tumino, R., Svenson, U., Rij, A. van, Baas, A.F., Bown, M.J., Samani, N.J., t'Hof, F.N.G. van, Tromp, G., Jones, G.T., Kuivaniemi, H., Elmore, J.R., Johansson, M., McKay, J., Scelo, G., Carreras-Torres, R., Gaborieau, V., Brennan, P., Bracci, P.M., Neale, R.E., Olson, S.H., Gallinger, S., Li, D., Petersen, G.M., Risch, H.A., Klein, A.P., Han, J., Abnet, C.C., Freedman, N.D., Taylor, P.R., Maris, J.M., Aben, K.K.H., Kiemeney, L.A., Vermeulen, S.H., Wiencke, J.K., Walsh, K.M., Wrensch, M., Rice, T., Turnbull, C., Litchfield, K., Paternoster, L., Standl, M., Abecasis, G.R., SanGiovanni, J.P., Li, Y., Mijatovic, V., Sapkota, Y., Low, S.K., Zondervan, K.T., Montgomery, G.W., Nyholt, D.R., Heel, D.A. van, Hunt, K., Arking, D.E., Ashar, F.N., Sotoodehnia, N., Woo, D., et al., Haycock, P.C., Burgess, S., Nounu, A., Zheng, J., Okoli, G.N., Bowden, J., Wade, K.H., Timpson, N.J., Evans, D.M., Willeit, P., Aviv, A., Gaunt, T.R., Hemani, G., Mangino, M., Ellis, H.P., Kurian, K.M., Pooley, K.A., Eeles, R.A., Lee, J.E., Fang, S., Chen, W.V., Law, M.H., Bowdler, L.M., Iles, M.M., Yang, Q., Worrall, B.B., Markus, H.S., Hung, R.J., Amos, C.I., Spurdle, A.B., Thompson, D.J., O'Mara, T.A., Wolpin, B., Amundadottir, L., Stolzenberg-Solomon, R., Trichopoulou, A., Onland-Moret, N.C., Lund, E., Duell, E.J., Canzian, F., Severi, G., Overvad, K., Gunter, M.J., Tumino, R., Svenson, U., Rij, A. van, Baas, A.F., Bown, M.J., Samani, N.J., t'Hof, F.N.G. van, Tromp, G., Jones, G.T., Kuivaniemi, H., Elmore, J.R., Johansson, M., McKay, J., Scelo, G., Carreras-Torres, R., Gaborieau, V., Brennan, P., Bracci, P.M., Neale, R.E., Olson, S.H., Gallinger, S., Li, D., Petersen, G.M., Risch, H.A., Klein, A.P., Han, J., Abnet, C.C., Freedman, N.D., Taylor, P.R., Maris, J.M., Aben, K.K.H., Kiemeney, L.A., Vermeulen, S.H., Wiencke, J.K., Walsh, K.M., Wrensch, M., Rice, T., Turnbull, C., Litchfield, K., Paternoster, L., Standl, M., Abecasis, G.R., SanGiovanni, J.P., Li, Y., Mijatovic, V., Sapkota, Y., Low, S.K., Zondervan, K.T., Montgomery, G.W., Nyholt, D.R., Heel, D.A. van, Hunt, K., Arking, D.E., Ashar, F.N., Sotoodehnia, N., Woo, D., and et al.
Abstract: Contains fulltext : 174181.pdf (publisher's version ) (Closed access), Importance: The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation. Objective: To conduct a Mendelian randomization study, using germline genetic variants as instrumental variables, to appraise the causal relevance of telomere length for risk of cancer and non-neoplastic diseases. Data Sources: Genomewide association studies (GWAS) published up to January 15, 2015. Study Selection: GWAS of noncommunicable diseases that assayed germline genetic variation and did not select cohort or control participants on the basis of preexisting diseases. Of 163 GWAS of noncommunicable diseases identified, summary data from 103 were available. Data Extraction and Synthesis: Summary association statistics for single nucleotide polymorphisms (SNPs) that are strongly associated with telomere length in the general population. Main Outcomes and Measures: Odds ratios (ORs) and 95% confidence intervals (CIs) for disease per standard deviation (SD) higher telomere length due to germline genetic variation. Results: Summary data were available for 35 cancers and 48 non-neoplastic diseases, corresponding to 420081 cases (median cases, 2526 per disease) and 1093105 controls (median, 6789 per disease). Increased telomere length due to germline genetic variation was generally associated with increased risk for site-specific cancers. The strongest associations (ORs [95% CIs] per 1-SD change in genetically increased telomere length) were observed for glioma, 5.27 (3.15-8.81); serous low-malignant-potential ovarian cancer, 4.35 (2.39-7.94); lung adenocarcinoma, 3.19 (2.40-4.22); neuroblastoma, 2.98 (1.92-4.62); bladder cancer, 2.19 (1.32-3.66); melanoma, 1.87 (1.55-2.26); testicular cancer, 1.76 (1.02-3.04); kidney cancer, 1.55 (1.08-2.23); and endometrial cancer, 1.31 (1.07-1.61). Associations were stronger for rarer cance
Published: 2017

33. Association between telomere length and risk of cancer and non-neoplastic diseases a mendelian randomization study

Author: Haycock, P. (Philip), Burgess, S. (Stephen), Nounu, A. (Aayah), Zheng, J. (Jie), Okoli, G.N. (George N.), Bowden, J., Wade, K.H. (Kaitlin Hazel), Timpson, N.J. (Nicholas J.), Evans, D.M. (David M.), Willeit, P. (Peter), Aviv, A. (Abraham), Gaunt, T.R. (Tom), Hemani, G., Mangino, M. (Massimo), Ellis, H.P. (Hayley Patricia), Kurian, K.M. (Kathreena M.), Pooley, K.A. (Karen A.), Eeles, R. (Rosalind), Lee, J.E. (Jeffrey E.), Fang, S. (Shenying), Chen, W.V. (Wei V.), Law, M.H. (Matthew H.), Bowdler, L.M. (Lisa M.), Iles, M.M. (Mark M.), Yang, Q. (Qiong Fang), Worrall, B.B. (Bradford B.), Markus, H.S. (Hugh), Hung, R.J. (Rayjean J.), Amos, W., Spurdle, A.B. (Amanda), Thompson, D. (Deborah), O'Mara, T.A. (Tracy A.), Wolpin, B. (Brian), Amundadottir, L. (Laufey), Stolzenberg-Solomon, R. (Rachael), Trichopoulou, A. (Antonia), Onland-Moret, N.C. (Charlotte), Lund, E. (Eiliv), Duell, E.J. (Eric), Canzian, F. (Federico), Severi, G. (Gianluca), Overvad, K. (Kim), Gunter, M.J. (Marc J.), Tumino, R. (Rosario), Svenson, U. (Ulrika), Rij, A.M. (Andre) van, Baas, A.F. (Annette), Bown, N., Samani, N.J. (Nilesh), Van t'Hof, F.N.G. (Femke N.G.), Tromp, G. (Gerard), Jones, G.T. (Gregory T.), Kuivaniemi, H. (Helena), Elmore, J.R. (James R.), Johansson, M. (Mattias), Mckay, J. (James), Scelo, G. (Ghislaine), Carreras-Torres, R. (Robert), Gaborieau, V. (Valerie), Brennan, P. (Paul), Bracci, P.M. (Paige M.), Neale, R.E. (Rachel E.), Olson, S.H. (Sara H.), Gallinger, S. (Steve), Li, D. (Donghui), Olson, S.H. (Sara), Risch, H. (Harvey), Klein, A.P. (Alison P.), Han, J., Abnet, C.C. (Christian C.), Freedman, N.D. (Neal D.), Taylor, P.R. (Phil R.), Maris, J.M. (John), Aben, K.K.H. (Katja), Kiemeney, L.A.L.M. (Bart), Vermeulen, S.H.H.M. (Sita), Wiencke, J.K. (John K.), Walsh, K.M. (Kyle M.), Wrensch, M. (Margaret), Rice, T. (Terri), Turnbull, C. (Clare), Litchfield, K. (Kevin), Paternoster, L. (Lavinia), Standl, M. (Marie), Abecasis, G.R. (Gonçalo), SanGiovanni, J.P. (John Paul), Li, Y. (Yong), Mijatovic, V. (Vladan), Sapkota, Y. (Yadav), Low, S.-K. (Siew-Kee), Zondervan, K.T. (Krina), Montgomery, G.W. (Grant W.), Nyholt, D.R. (Dale), Heel, D.A. (David) van, Hunt, K. (Karen), Arking, D.E. (Dan), Ashar, F.N. (Foram N.), Sotoodehnia, N. (Nona), Woo, D. (Daniel), Rosand, J. (Jonathan), Comeau, M.E. (Mary E.), Brown, W.M. (W. Mark), Silverman, E. (Edwin), Hokanson, J.E. (John E.), Cho, M.H. (Michael), Hui, J. (Jennie), Ferreira, M.A. (Manuel A.), Thompson, P.J. (Philip J.), Morrison, A.C. (Alanna), Felix, J.F. (Janine F.), Smith, N.L. (Nicholas L.), Christiano, A.M. (Angela), Petukhova, L. (Lynn), Betz, R.C. (Regina), Fan, X. (Xing), Zhang, X. (Xuejun), Zhu, C. (Caihong), Langefeld, C.D. (Carl), Thompson, S.D. (Susan D.), Wang, F. (Feijie), Lin, X. (Xu), Schwartz, D.A. (David A.), Fingerlin, T.E. (Tasha E.), Rotter, J.I. (Jerome I.), Cotch, M.F. (Mary Frances), Jensen, R.A. (Richard A.), Munz, M. (Matthias), Dommisch, H. (Henrik), Schaefer, A. (Antje), Han, F. (Fang), Ollila, H.M., Hillary, R.P. (Ryan P.), Albagha, O.M.E. (Omar M.), Ralston, S.H. (Stuart), Zeng, C. (Chenjie), Zheng, W. (Wei), Shu, X.-O. (Xiao-Ou), Reis, A. (André), Uebe, S. (Steffen), Hüffmeier, U. (Ulrike), Kawamura, Y. (Yoshiya), Otowa, T. (Takeshi), Sasaki, T. (Tsukasa), Hibberd, M.L. (Martin), Davila, S. (Sonia), Xie, G. (Gang), Siminovitch, K.A. (Katherine), Bei, J.-X. (Jin-Xin), Zeng, Y.X., Försti, A. (Asta), Chen, B. (Bowang), Landi, S. (Stefano), Franke, A. (Andre), Fischer, A. (Annegret), Ellinghaus, D. (David), Flores, C. (Carlos), Noth, I. (Imre), Ma, S.-F. (Shwu-Fan), Foo, J.-N. (Jia-Nee), Liu, J. (Jianjun), Kim, J.-W. (Jong-Won), Cox, D.G. (David), Delattre, O. (Olivier), Mirabeau, O. (Olivier), Skibola, C.F. (Christine F.), Tang, C.S. (Clara S.), Garcia-Barcelo, M., Chang, K.-P. (Kai-Ping), Su, W.-H. (Wen-Hui), Chang, Y.-S. (Yu-Sun), Martin, N.G. (Nicholas G.), Gordon, S.D. (Scott D.), Wade, T.D. (Tracey D.), Lee, C. (Chaeyoung), Kubo, M. (Michiaki), Cha, P.-C. (Pei-Chieng), Nakamura, Y. (Yusuke), Levy, D. (Daniel), Kimura, M. (Masayuki), Hwang, S.-J. (Shih-Jen), Hunt, S.C. (Steven), Spector, T.D. (Timothy), Soranzo, N. (Nicole), Manichaikul, A.W. (Ani W.), Barr, R.G. (Graham), Kahali, B. (Bratati), Speliotes, E.K. (Elizabeth), Yerges-Armstrong, L.M. (Laura), Cheng, C-Y. (Ching-Yu), Jonas, J.B. (Jost B.), Wong, T.Y. (Tien Yin), Fogh, I. (Isabella), Lin, K. (Kuang), Powell, J. (John), Rice, K. (Kenneth), Relton, C.L. (Caroline), Martin, R.M. (Richard M.), Smith, A.V. (Davey), Haycock, P. (Philip), Burgess, S. (Stephen), Nounu, A. (Aayah), Zheng, J. (Jie), Okoli, G.N. (George N.), Bowden, J., Wade, K.H. (Kaitlin Hazel), Timpson, N.J. (Nicholas J.), Evans, D.M. (David M.), Willeit, P. (Peter), Aviv, A. (Abraham), Gaunt, T.R. (Tom), Hemani, G., Mangino, M. (Massimo), Ellis, H.P. (Hayley Patricia), Kurian, K.M. (Kathreena M.), Pooley, K.A. (Karen A.), Eeles, R. (Rosalind), Lee, J.E. (Jeffrey E.), Fang, S. (Shenying), Chen, W.V. (Wei V.), Law, M.H. (Matthew H.), Bowdler, L.M. (Lisa M.), Iles, M.M. (Mark M.), Yang, Q. (Qiong Fang), Worrall, B.B. (Bradford B.), Markus, H.S. (Hugh), Hung, R.J. (Rayjean J.), Amos, W., Spurdle, A.B. (Amanda), Thompson, D. (Deborah), O'Mara, T.A. (Tracy A.), Wolpin, B. (Brian), Amundadottir, L. (Laufey), Stolzenberg-Solomon, R. (Rachael), Trichopoulou, A. (Antonia), Onland-Moret, N.C. (Charlotte), Lund, E. (Eiliv), Duell, E.J. (Eric), Canzian, F. (Federico), Severi, G. (Gianluca), Overvad, K. (Kim), Gunter, M.J. (Marc J.), Tumino, R. (Rosario), Svenson, U. (Ulrika), Rij, A.M. (Andre) van, Baas, A.F. (Annette), Bown, N., Samani, N.J. (Nilesh), Van t'Hof, F.N.G. (Femke N.G.), Tromp, G. (Gerard), Jones, G.T. (Gregory T.), Kuivaniemi, H. (Helena), Elmore, J.R. (James R.), Johansson, M. (Mattias), Mckay, J. (James), Scelo, G. (Ghislaine), Carreras-Torres, R. (Robert), Gaborieau, V. (Valerie), Brennan, P. (Paul), Bracci, P.M. (Paige M.), Neale, R.E. (Rachel E.), Olson, S.H. (Sara H.), Gallinger, S. (Steve), Li, D. (Donghui), Olson, S.H. (Sara), Risch, H. (Harvey), Klein, A.P. (Alison P.), Han, J., Abnet, C.C. (Christian C.), Freedman, N.D. (Neal D.), Taylor, P.R. (Phil R.), Maris, J.M. (John), Aben, K.K.H. (Katja), Kiemeney, L.A.L.M. (Bart), Vermeulen, S.H.H.M. (Sita), Wiencke, J.K. (John K.), Walsh, K.M. (Kyle M.), Wrensch, M. (Margaret), Rice, T. (Terri), Turnbull, C. (Clare), Litchfield, K. (Kevin), Paternoster, L. (Lavinia), Standl, M. (Marie), Abecasis, G.R. (Gonçalo), SanGiovanni, J.P. (John Paul), Li, Y. (Yong), Mijatovic, V. (Vladan), Sapkota, Y. (Yadav), Low, S.-K. (Siew-Kee), Zondervan, K.T. (Krina), Montgomery, G.W. (Grant W.), Nyholt, D.R. (Dale), Heel, D.A. (David) van, Hunt, K. (Karen), Arking, D.E. (Dan), Ashar, F.N. (Foram N.), Sotoodehnia, N. (Nona), Woo, D. (Daniel), Rosand, J. (Jonathan), Comeau, M.E. (Mary E.), Brown, W.M. (W. Mark), Silverman, E. (Edwin), Hokanson, J.E. (John E.), Cho, M.H. (Michael), Hui, J. (Jennie), Ferreira, M.A. (Manuel A.), Thompson, P.J. (Philip J.), Morrison, A.C. (Alanna), Felix, J.F. (Janine F.), Smith, N.L. (Nicholas L.), Christiano, A.M. (Angela), Petukhova, L. (Lynn), Betz, R.C. (Regina), Fan, X. (Xing), Zhang, X. (Xuejun), Zhu, C. (Caihong), Langefeld, C.D. (Carl), Thompson, S.D. (Susan D.), Wang, F. (Feijie), Lin, X. (Xu), Schwartz, D.A. (David A.), Fingerlin, T.E. (Tasha E.), Rotter, J.I. (Jerome I.), Cotch, M.F. (Mary Frances), Jensen, R.A. (Richard A.), Munz, M. (Matthias), Dommisch, H. (Henrik), Schaefer, A. (Antje), Han, F. (Fang), Ollila, H.M., Hillary, R.P. (Ryan P.), Albagha, O.M.E. (Omar M.), Ralston, S.H. (Stuart), Zeng, C. (Chenjie), Zheng, W. (Wei), Shu, X.-O. (Xiao-Ou), Reis, A. (André), Uebe, S. (Steffen), Hüffmeier, U. (Ulrike), Kawamura, Y. (Yoshiya), Otowa, T. (Takeshi), Sasaki, T. (Tsukasa), Hibberd, M.L. (Martin), Davila, S. (Sonia), Xie, G. (Gang), Siminovitch, K.A. (Katherine), Bei, J.-X. (Jin-Xin), Zeng, Y.X., Försti, A. (Asta), Chen, B. (Bowang), Landi, S. (Stefano), Franke, A. (Andre), Fischer, A. (Annegret), Ellinghaus, D. (David), Flores, C. (Carlos), Noth, I. (Imre), Ma, S.-F. (Shwu-Fan), Foo, J.-N. (Jia-Nee), Liu, J. (Jianjun), Kim, J.-W. (Jong-Won), Cox, D.G. (David), Delattre, O. (Olivier), Mirabeau, O. (Olivier), Skibola, C.F. (Christine F.), Tang, C.S. (Clara S.), Garcia-Barcelo, M., Chang, K.-P. (Kai-Ping), Su, W.-H. (Wen-Hui), Chang, Y.-S. (Yu-Sun), Martin, N.G. (Nicholas G.), Gordon, S.D. (Scott D.), Wade, T.D. (Tracey D.), Lee, C. (Chaeyoung), Kubo, M. (Michiaki), Cha, P.-C. (Pei-Chieng), Nakamura, Y. (Yusuke), Levy, D. (Daniel), Kimura, M. (Masayuki), Hwang, S.-J. (Shih-Jen), Hunt, S.C. (Steven), Spector, T.D. (Timothy), Soranzo, N. (Nicole), Manichaikul, A.W. (Ani W.), Barr, R.G. (Graham), Kahali, B. (Bratati), Speliotes, E.K. (Elizabeth), Yerges-Armstrong, L.M. (Laura), Cheng, C-Y. (Ching-Yu), Jonas, J.B. (Jost B.), Wong, T.Y. (Tien Yin), Fogh, I. (Isabella), Lin, K. (Kuang), Powell, J. (John), Rice, K. (Kenneth), Relton, C.L. (Caroline), Martin, R.M. (Richard M.), and Smith, A.V. (Davey)
Abstract: IMPORTANCE: The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation. OBJECTIVE: To conduct a Mendelian randomization study, using germline genetic variants as instrumental variables, to appraise the causal relevance of telomere length for risk of cancer and non-neoplastic diseases. DATA SOURCES: Genomewide association studies (GWAS) published up to January 15, 2015. STUDY SELECTION: GWAS of noncommunicable diseases that assayed germline genetic variation and did not select cohort or control participants on the basis of preexisting diseases. Of 163 GWAS of noncommunicable diseases identified, summary data from 103 were available. DATA EXTRACTION AND SYNTHESIS: Summary association statistics for single nucleotide polymorphisms (SNPs) that are strongly associated with telomere length in the general population. MAIN OUTCOMES AND MEASURES: Odds ratios (ORs) and 95% confidence intervals (CIs) for disease per standard deviation (SD) higher telomere length due to germline genetic variation. RESULTS: Summary data were available for 35 cancers and 48 non-neoplastic diseases, corresponding to 420 081 cases (median cases, 2526 per disease) and 1 093 105 controls (median, 6789 per disease). Increased telomere length due to germline genetic variation was generally associated with increased risk for site-specific cancers. The strongest associations (ORs [95% CIs] per 1-SD change in genetically increased telomere length) were observed for glioma, 5.27 (3.15-8.81); serous low-malignant-potential ovarian cancer, 4.35 (2.39-7.94); lung adenocarcinoma, 3.19 (2.40-4.22); neuroblastoma, 2.98 (1.92-4.62); bladder cancer, 2.19 (1.32-3.66); melanoma, 1.87 (1.55-2.26); testicular cancer, 1.76 (1.02-3.04); kidney cancer, 1.55 (1.08-2.23); and endometrial cancer, 1.31 (1.07-1.61). Associations were stronger for rarer ca
Published: 2017
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34. Comparison of Three Targeted Approaches to Screening for Abdominal Aortic Aneurysm Based on Cardiovascular Risk

Author: Jones, G.T., primary, Hill, B.G., additional, and Curtis, N., additional
Published: 2016
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35. The relationship between back pain and mortality in older adults varies with disability and gender: Results from the Cambridge City over-75s Cohort (CC75C) study

Author: Docking, R.E., Fleming, J., Brayne, C., Zhao, J., Macfarlane, G.J., and Jones, G.T.
Subjects: RZ, R1
Abstract: Background: \ud This study aims to determine whether older adults reporting back pain (BP) are at increased risk of premature mortality, specifically, to examine the association with disabling/non-disabling pain separately.\ud \ud Methods:\ud Participants aged ≥75 years were recruited to the Cambridge City over-75s Cohort (CC75C) study. Participants answered interviewer-administered questions on BP and were followed up until death. The relationship between BP and mortality was examined using Cox regression, adjusted for potential confounding factors. Separate models were computed for men and women.\ud \ud Results:\ud From 1174 individuals with BP data, the date of death was known for 1158 (99%). A significant association was found between disabling BP and mortality (hazard ratio: 1.4; 95% confidence interval: 1.1–1.8) and this remained, albeit of borderline significance, following adjustment for socio-demographic variables and potential disease markers (1.3; 0.99–1.7). Further, this association was found to vary with sex: women experienced a 40% increase in the risk of mortality associated with disabling BP (1.4; 1.1–1.9), whereas no such increase was observed for men (1.0; 0.5–1.9). Participants with non-disabling BP were not at increased risk of mortality.\ud \ud Conclusions:\ud This study confirmed previous findings regarding the relationship between pain and excess mortality. Further, we have shown that, among older adults, this association is specific to disabling pain and to women. Clinicians should be aware not only of the short-term implications of disabling BP but also the longer-term effects. Future research should attempt to understand the mechanisms underpinning this relationship to avoid excess mortality and should aim to determine why the relationship differs in men and women.
Published: 2015

36. Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

Author: Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A.B., Norddahl, G.L., Helgadottir, A., Magnusdottir, A., Jonasdottir, A., Gretarsdottir, S., Jonsdottir, I., Steinthorsdottir, V., Rafnar, T., Swinkels, D.W., Galesloot, T.E., Grarup, N., Jorgensen, T., Vestergaard, H., Hansen, T., Lauritzen, T., Linneberg, A., Friedrich, N., Krarup, N.T., Fenger, M., Abildgaard, U., Hansen, P.R., Galloe, A.M., Braund, P.S., Nelson, C.P., Hall, A.S., Williams, M.J., Rij, A.M. van, Jones, G.T., Patel, R.S., Levey, A.I., Hayek, S., Shah, S.H., Reilly, M., Eyjolfsson, G.I., Sigurdardottir, O., Olafsson, I., Kiemeney, L.A.L.M., Quyyumi, A.A., Rader, D.J., Kraus, W.E., Samani, N.J., Pedersen, O., Thorgeirsson, G., Masson, G., Holm, H., Gudbjartsson, D., Sulem, P., Thorsteinsdottir, U., Stefansson, K., Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A.B., Norddahl, G.L., Helgadottir, A., Magnusdottir, A., Jonasdottir, A., Gretarsdottir, S., Jonsdottir, I., Steinthorsdottir, V., Rafnar, T., Swinkels, D.W., Galesloot, T.E., Grarup, N., Jorgensen, T., Vestergaard, H., Hansen, T., Lauritzen, T., Linneberg, A., Friedrich, N., Krarup, N.T., Fenger, M., Abildgaard, U., Hansen, P.R., Galloe, A.M., Braund, P.S., Nelson, C.P., Hall, A.S., Williams, M.J., Rij, A.M. van, Jones, G.T., Patel, R.S., Levey, A.I., Hayek, S., Shah, S.H., Reilly, M., Eyjolfsson, G.I., Sigurdardottir, O., Olafsson, I., Kiemeney, L.A.L.M., Quyyumi, A.A., Rader, D.J., Kraus, W.E., Samani, N.J., Pedersen, O., Thorgeirsson, G., Masson, G., Holm, H., Gudbjartsson, D., Sulem, P., Thorsteinsdottir, U., and Stefansson, K.
Abstract: Item does not contain fulltext, BACKGROUND: Several sequence variants are known to have effects on serum levels of non-high-density lipoprotein (HDL) cholesterol that alter the risk of coronary artery disease. METHODS: We sequenced the genomes of 2636 Icelanders and found variants that we then imputed into the genomes of approximately 398,000 Icelanders. We tested for association between these imputed variants and non-HDL cholesterol levels in 119,146 samples. We then performed replication testing in two populations of European descent. We assessed the effects of an implicated loss-of-function variant on the risk of coronary artery disease in 42,524 case patients and 249,414 controls from five European ancestry populations. An augmented set of genomes was screened for additional loss-of-function variants in a target gene. We evaluated the effect of an implicated variant on protein stability. RESULTS: We found a rare noncoding 12-base-pair (bp) deletion (del12) in intron 4 of ASGR1, which encodes a subunit of the asialoglycoprotein receptor, a lectin that plays a role in the homeostasis of circulating glycoproteins. The del12 mutation activates a cryptic splice site, leading to a frameshift mutation and a premature stop codon that renders a truncated protein prone to degradation. Heterozygous carriers of the mutation (1 in 120 persons in our study population) had a lower level of non-HDL cholesterol than noncarriers, a difference of 15.3 mg per deciliter (0.40 mmol per liter) (P=1.0x10(-16)), and a lower risk of coronary artery disease (by 34%; 95% confidence interval, 21 to 45; P=4.0x10(-6)). In a larger set of sequenced samples from Icelanders, we found another loss-of-function ASGR1 variant (p.W158X, carried by 1 in 1850 persons) that was also associated with lower levels of non-HDL cholesterol (P=1.8x10(-3)). CONCLUSIONS: ASGR1 haploinsufficiency was associated with reduced levels of non-HDL cholesterol and a reduced risk of coronary artery disease. (Funded by the National Institutes of Health
Published: 2016

37. Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout

Author: Rasheed, H., Phipps-Green, A.J., Topless, R., Smith, M.D., Hill, C., Lester, S., Rischmueller, M., Janssen, M., Jansen, T.L.Th.A., Joosten, L.A.B., Radstake, T.R., Riches, P.L., Tausche, A.K., Liote, F., So, A., Rij, A. van, Jones, G.T., McCormick, S.P., Harrison, A.A., Stamp, L.K., Dalbeth, N., Merriman, T.R., Rasheed, H., Phipps-Green, A.J., Topless, R., Smith, M.D., Hill, C., Lester, S., Rischmueller, M., Janssen, M., Jansen, T.L.Th.A., Joosten, L.A.B., Radstake, T.R., Riches, P.L., Tausche, A.K., Liote, F., So, A., Rij, A. van, Jones, G.T., McCormick, S.P., Harrison, A.A., Stamp, L.K., Dalbeth, N., and Merriman, T.R.
Abstract: Contains fulltext : 171388.pdf (publisher's version ) (Closed access), OBJECTIVE: Gout is associated with dyslipidaemia. Association of the apolipoprotein A1-C3-A4 gene cluster with gout has previously been reported in a small study. To investigate a possible causal role for this locus in gout, we tested the association of genetic variants from APOA1 (rs670) and APOC3 (rs5128) with gout. METHODS: We studied data for 2452 controls and 2690 clinically ascertained gout cases of European and New Zealand Polynesian (Maori and Pacific) ancestry. Data were also used from the publicly available Atherosclerosis Risk in Communities study (n = 5367) and the Framingham Heart Study (n = 2984). Multivariate adjusted logistic and linear regression was used to test the association of single-nucleotide polymorphisms with gout risk, serum urate, triglyceride and high-density lipoprotein cholesterol (HDL-C). RESULTS: In Polynesians, the T-allele of rs670 (APOA1) increased (odds ratio, OR = 1.53, P = 4.9 x 10(-6)) and the G-allele of rs5128 (APOC3) decreased the risk of gout (OR = 0.86, P = 0.026). In Europeans, there was a strong trend to a risk effect of the T-allele for rs670 (OR = 1.11, P = 0.055), with a significant protective effect of the G-allele for rs5128 being observed after adjustment for triglycerides and HDL-C (OR = 0.81, P = 0.039). The effect at rs5128 was specific to males in both Europeans and Polynesians. Association in Polynesians was independent of any effect of rs670 and rs5128 on triglyceride and HDL-C levels. There was no evidence for association of either single-nucleotide polymorphism with serum urate levels (P 0.10). CONCLUSION: Our data, replicating a previous study, supports the hypothesis that the apolipoprotein A1-C3-A4 gene cluster plays a causal role in gout.
Published: 2016

38. Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms

Author: Hof, F.N. van 't, Ruigrok, Y.M., Lee, C.H., Ripke, S., Anderson, G., Baas, A.F., Blankensteijn, J.D., Bottinger, E.P., Bown, M.J., Broderick, J., Bijlenga, P., Carrell, D.S., Crawford, D.C., Crosslin, D.R., Ebeling, C., Eriksson, J.G., Fornage, M., Foroud, T., von Und Zu Fraunberg, M., Friedrich, C.M., Gaal, E.I., Gottesman, O., Guo, D.C., Harrison, S.C., Hernesniemi, J., Hofman, A., Inoue, I., Jaaskelainen, J.E., Jones, G.T., Kiemeney, L.A., Kivisaari, R., Ko, N., Koskinen, S., Kubo, M., Kullo, I.J., Kuivaniemi, H., Kurki, M.I., Laakso, A., Lai, D., Leal, S.M., Lehto, H., Lemaire, S.A., Low, S.K., Malinowski, J., McCarty, C.A., Milewicz, D.M., Mosley, T.H., Nakamura, Y., Nakaoka, H., Niemela, M., Pacheco, J., Peissig, P.L., Pera, J., Rasmussen-Torvik, L., Ritchie, M.D., Rivadeneira, F., Rij, A.M. van, Santos-Cortez, R.L., Saratzis, A., Slowik, A., Takahashi, A., Tromp, G., Uitterlinden, A.G., Verma, S.S., Vermeulen, S.H., Wang, G.T., Han, B., Rinkel, G.J., Bakker, P.I. de, Graaf, J. de, et al., Hof, F.N. van 't, Ruigrok, Y.M., Lee, C.H., Ripke, S., Anderson, G., Baas, A.F., Blankensteijn, J.D., Bottinger, E.P., Bown, M.J., Broderick, J., Bijlenga, P., Carrell, D.S., Crawford, D.C., Crosslin, D.R., Ebeling, C., Eriksson, J.G., Fornage, M., Foroud, T., von Und Zu Fraunberg, M., Friedrich, C.M., Gaal, E.I., Gottesman, O., Guo, D.C., Harrison, S.C., Hernesniemi, J., Hofman, A., Inoue, I., Jaaskelainen, J.E., Jones, G.T., Kiemeney, L.A., Kivisaari, R., Ko, N., Koskinen, S., Kubo, M., Kullo, I.J., Kuivaniemi, H., Kurki, M.I., Laakso, A., Lai, D., Leal, S.M., Lehto, H., Lemaire, S.A., Low, S.K., Malinowski, J., McCarty, C.A., Milewicz, D.M., Mosley, T.H., Nakamura, Y., Nakaoka, H., Niemela, M., Pacheco, J., Peissig, P.L., Pera, J., Rasmussen-Torvik, L., Ritchie, M.D., Rivadeneira, F., Rij, A.M. van, Santos-Cortez, R.L., Saratzis, A., Slowik, A., Takahashi, A., Tromp, G., Uitterlinden, A.G., Verma, S.S., Vermeulen, S.H., Wang, G.T., Han, B., Rinkel, G.J., Bakker, P.I. de, Graaf, J. de, and et al.
Abstract: Contains fulltext : 171496.pdf (publisher's version ) (Open Access), BACKGROUND: Intracranial aneurysms (IAs), abdominal aortic aneurysms (AAAs), and thoracic aortic aneurysms (TAAs) all have a familial predisposition. Given that aneurysm types are known to co-occur, we hypothesized that there may be shared genetic risk factors for IAs, AAAs, and TAAs. METHODS AND RESULTS: We performed a mega-analysis of 1000 Genomes Project-imputed genome-wide association study (GWAS) data of 4 previously published aneurysm cohorts: 2 IA cohorts (in total 1516 cases, 4305 controls), 1 AAA cohort (818 cases, 3004 controls), and 1 TAA cohort (760 cases, 2212 controls), and observed associations of 4 known IA, AAA, and/or TAA risk loci (9p21, 18q11, 15q21, and 2q33) with consistent effect directions in all 4 cohorts. We calculated polygenic scores based on IA-, AAA-, and TAA-associated SNPs and tested these scores for association to case-control status in the other aneurysm cohorts; this revealed no shared polygenic effects. Similarly, linkage disequilibrium-score regression analyses did not show significant correlations between any pair of aneurysm subtypes. Last, we evaluated the evidence for 14 previously published aneurysm risk single-nucleotide polymorphisms through collaboration in extended aneurysm cohorts, with a total of 6548 cases and 16 843 controls (IA) and 4391 cases and 37 904 controls (AAA), and found nominally significant associations for IA risk locus 18q11 near RBBP8 to AAA (odds ratio [OR]=1.11; P=4.1x10(-5)) and for TAA risk locus 15q21 near FBN1 to AAA (OR=1.07; P=1.1x10(-3)). CONCLUSIONS: Although there was no evidence for polygenic overlap between IAs, AAAs, and TAAs, we found nominally significant effects of two established risk loci for IAs and TAAs in AAAs. These two loci will require further replication.
Published: 2016

39. Chronic pelvic pain in women of reproductive and post-reproductive age: a population-based study

Author: Ayorinde, A.A., primary, Bhattacharya, S., additional, Druce, K.L., additional, Jones, G.T., additional, and Macfarlane, G.J., additional
Published: 2016
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40. Re: ‘Self-referral to the NHS Abdominal Aortic Screening Programme’

Author: Khashram, M., primary, Jones, G.T., additional, and Roake, J.A., additional
Published: 2016
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41. A study of the centrally produced K(892)(892)and φω systems in pp interactions at 450 GeV/c

Author: D. Barberis, W. Beusch, F.G. Binon, A.M. Blick, F.E. Close, K.M. Danielsen, A.V. Dolgopolov, S.V. Donskov, B.C. Earl, D. Evans, B.R. French, T. Hino, S. Inaba, A.V. Inyakin, T. Ishida, A. Jacholkowski, T. Jacobsen, Jones G.T, G.V. Khaustov, T. Kinashi, J.B. Kinson, A. Kirk, W. Klempt, V. Kolosov, A.A. Kondashov, A.A. Lednev, V. Lenti, S. Maljukov, P. Martinengo, I. Minashvili, T. Nakagawa, K.L. Norman, J.P. Peigneux, S.A. Polovnikov, V.A. Polyakov, V. Romanovsky, H. Rotscheidt, V. Rumyantsev, N. Russakovich, V.D. Samoylenko, A. Semenov, M. Sené, R. Sené, P.M. Shagin, H. Shimizu, A.V. Singovsky, A. Sobol, A. Solovjev, M. Stassinaki, J.P. Stroot, V.P. Sugonyaev, K. Takamatsu, G. Tchlatchidze, T. Tsuru, M. Venables, O. Villalobos Baillie, M.F. Votruba, and Y. Yasu
Subjects: Physics, Nuclear physics, Nuclear and High Energy Physics, Pomeron, Near threshold, Particle physics, Glueball, Mass spectrum, State (functional analysis), Omega
Abstract: A study of the reactions pp -> pfps(K+K-pi+pi-) and pp -> pfps(K+K-pi+pi-pi0) shows evidence for the K*K* and phi omega channels respectively. The K*K* mass spectrum shows a broad distribution with a maximum near threshold and an angular analysis shows that it is compatible with having JP = 2+. The behaviour of the cross-section as a function of centre of mass energy, and the four momentum transfer dependence, are compatible with what would be expected if the K*K* system was produced via double Pomeron exchange. The dPT behaviour of the phi omega channel is similar to what has been observed for all the undisputed qqbar states. In contrast, the dPT behaviour of the K*K* final state is similar to what has been observed for the phi phi final state and for previously observed glueball candidates.
Published: 1998
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42. Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

Author: Peters, M.J., Broer, L., Willemen, H.L.D.M., Eiriksdottir, G., Hocking, L.J., Holliday, K.L., Horan, M.A., Meulenbelt, I., Neogi, T., Popham, M., Schmidt, C.O., Soni, A., Valdes, A.M., Amin, N., Dennison, E.M., Eijkelkamp, N., Harris, T.B., Hart, D.J., Hofman, A., Huygen, F.J.P.M., Jameson, K.A., Jones, G.T., Launer, L.J., Kerkhof, H.J.M., Kruijf, M. de, McBeth, J., Kloppenburg, M., Ollier, W.E., Oostra, B., Payton, A., Rivadeneira, F., Smith, B.H., Smith, A.V., Stolk, L., Teumer, A., Thomson, W., Uitterlinden, A.G., Wang, K., Wingerden, S.H. van, Arden, N.K., Cooper, C., Felson, D., Gudnason, V., Macfarlane, G.J., Pendleton, N., Slagboom, P.E., Spector, T.D., Volzke, H., Kavelaars, A., Duijn, C.M. van, Williams, F.M.K., and Meurs, J.B.J. van
Published: 2013

43. Erratum to “Rapidity and transverse momentum dependence of inclusive [formula omitted] production in pp collisions at [formula omitted]” [Phys. Lett. B 704 (5) (2011) 442]

Author: Aamodt, K., Abrahantes Quintana, A., Adamová, D., Adare, A.M., Aggarwal, M.M., Aglieri Rinella, G., Agocs, A.G., Agostinelli, A., Aguilar Salazar, S., Ahammed, Z., Ahmad, N., Ahmad Masoodi, A., Ahn, S.U., Akindinov, A., Aleksandrov, D., Alessandro, B., Alfaro Molina, R., Alici, A., Alkin, A., Almaráz Aviña, E., Alme, J., Alt, T., Altini, V., Altsybeev, I., Andrei, C., Andronic, A., Anguelov, V., Anson, C., Antičić, T., Antinori, F., Antonioli, P., Aphecetche, L., Appelshäuser, H., Arbor, N., Arcelli, S., Arend, A., Armesto, N., Arnaldi, R., Aronsson, T., Arsene, I.C., Asryan, A., Augustinus, A., Averbeck, R., Awes, T.C., Äystö, J., Azmi, M.D., Bach, M., Badalà, A., Baek, Y.W., Bailhache, R., Bala, R., Baldini Ferroli, R., Baldisseri, A., Baldit, A., Bán, J., Barbera, R., Barile, F., Barnaföldi, G.G., Barnby, L.S., Barret, V., Bartke, J., Basile, M., Bastid, N., Bathen, B., Batigne, G., Batyunya, B., Baumann, C., Bearden, I.G., Beck, H., Belikov, I., Bellini, F., Bellwied, R., Belmont-Moreno, E., Beole, S., Berceanu, I., Bercuci, A., Berdermann, E., Berdnikov, Y., Bergmann, C., Betev, L., Bhasin, A., Bhati, A.K., Bianchi, L., Bianchi, N., Bianchin, C., Bielčík, J., Bielčíková, J., Bilandzic, A., Biolcati, E., Blanc, A., Blanco, F., Blau, D., Blume, C., Bock, N., Bogdanov, A., Bøggild, H., Bogolyubsky, M., Boldizsár, L., Bombara, M., Bombonati, C., Book, J., Borel, H., Borissov, A., Bortolin, C., Bose, S., Bossú, F., Botje, M., Böttger, S., Boyer, B., Braun-Munzinger, P., Bravina, L., Bregant, M., Breitner, T., Broz, M., Brun, R., Bruna, E., Bruno, G.E., Budnikov, D., Buesching, H., Bufalino, S., Busch, O., Buthelezi, Z., Caffarri, D., Cai, X., Caines, H., Calvo Villar, E., Camerini, P., Canoa Roman, V., Cara Romeo, G., Carena, F., Carena, W., Carminati, F., Casanova Díaz, A., Caselle, M., Castillo Castellanos, J., Catanescu, V., Cavicchioli, C., Cepila, J., Cerello, P., Chang, B., Chapeland, S., Charvet, J.L., Chattopadhyay, S., Cherney, M., Cheshkov, C., Cheynis, B., Chiavassa, E., Chibante Barroso, V., Chinellato, D.D., Chochula, P., Chojnacki, M., Christakoglou, P., Christensen, C.H., Christiansen, P., Chujo, T., Cicalo, C., Cifarelli, L., Cindolo, F., Cleymans, J., Coccetti, F., Coffin, J.-P., Conesa Balbastre, G., Conesa del Valle, Z., Constantin, P., Contin, G., Contreras, J.G., Cormier, T.M., Corrales Morales, Y., Cortés Maldonado, I., Cortese, P., Cosentino, M.R., Costa, F., Cotallo, M.E., Crescio, E., Crochet, P., Cuautle, E., Cunqueiro, L., D Erasmo, G., Dainese, A., Dalsgaard, H.H., Danu, A., Das, D., Das, I., Dash, A., Dash, S., De, S., De Azevedo Moregula, A., de Barros, G.O.V., De Caro, A., de Cataldo, G., de Cuveland, J., De Falco, A., De Gruttola, D., De Marco, N., De Pasquale, S., de Rooij, R., Del Castillo Sanchez, E., Delagrange, H., Delgado Mercado, Y., Dellacasa, G., Deloff, A., Demanov, V., Dénes, E., Deppman, A., Di Bari, D., Di Giglio, C., Di Liberto, S., Di Mauro, A., Di Nezza, P., Dietel, T., Divià, R., Djuvsland, Ø., Dobrin, A., Dobrowolski, T., Domínguez, I., Dönigus, B., Dordic, O., Driga, O., Dubey, A.K., Ducroux, L., Dupieux, P., Dutta Majumdar, A.K., Dutta Majumdar, M.R., Elia, D., Emschermann, D., Engel, H., Erdal, H.A., Espagnon, B., Estienne, M., Esumi, S., Evans, D., Evrard, S., Eyyubova, G., Fabris, D., Faivre, J., Falchieri, D., Fantoni, A., Fasel, M., Fearick, R., Fedunov, A., Fehlker, D., Fekete, V., Felea, D., Feofilov, G., Fernández Téllez, A., Ferreiro, E.G., Ferretti, A., Ferretti, R., Figueredo, M.A.S., Filchagin, S., Fini, R., Finogeev, D., Fionda, F.M., Fiore, E.M., Floris, M., Foertsch, S., Foka, P., Fokin, S., Fragiacomo, E., Fragkiadakis, M., Frankenfeld, U., Fuchs, U., Furano, F., Furget, C., Fusco Girard, M., Gaardhøje, J.J., Gadrat, S., Gagliardi, M., Gago, A., Gallio, M., Ganoti, P., Garabatos, C., Garcia-Solis, E., Gemme, R., Gerhard, J., Germain, M., Geuna, C., Gheata, A., Gheata, M., Ghidini, B., Ghosh, P., Gianotti, P., Girard, M.R., Giubellino, P., Gladysz-Dziadus, E., Glässel, P., Gomez, R., González-Trueba, L.H., González-Zamora, P., Gorbunov, S., Gotovac, S., Grabski, V., Graczykowski, L.K., Grajcarek, R., Grelli, A., Grigoras, A., Grigoras, C., Grigoriev, V., Grigoryan, A., Grigoryan, S., Grinyov, B., Grion, N., Gros, P., Grosse-Oetringhaus, J.F., Grossiord, J.-Y., Guber, F., Guernane, R., Guerra Gutierrez, C., Guerzoni, B., Gulbrandsen, K., Gulkanyan, H., Gunji, T., Gupta, A., Gupta, R., Gutbrod, H., Haaland, Ø., Hadjidakis, C., Haiduc, M., Hamagaki, H., Hamar, G., Hanratty, L.D., Harmanova, Z., Harris, J.W., Hartig, M., Hasegan, D., Hatzifotiadou, D., Hayrapetyan, A., Heide, M., Heinz, M., Helstrup, H., Herghelegiu, A., Herrera Corral, G., Herrmann, N., Hetland, K.F., Hicks, B., Hille, P.T., Hippolyte, B., Horaguchi, T., Hori, Y., Hristov, P., Hřivnáčová, I., Huang, M., Huber, S., Humanic, T.J., Hwang, D.S., Ilkaev, R., Ilkiv, I., Inaba, M., Incani, E., Innocenti, G.M., Ippolitov, M., Irfan, M., Ivan, C., Ivanov, A., Ivanov, M., Ivanov, V., Jachołkowski, A., Jacobs, P.M., Jancurová, L., Jangal, S., Janik, M.A., Janik, R., Jayarathna, P.H.S.Y., Jena, S., Jirden, L., Jones, G.T., Jones, P.G., Jovanović, P., Jung, H., Jung, W., Jusko, A., Kalcher, S., Kaliňák, P., Kalisky, M., Kalliokoski, T., Kalweit, A., Kamermans, R., Kanaki, K., Kang, E., Kang, J.H., Kaplin, V., Karasu Uysal, A., Karavichev, O., Karavicheva, T., Karpechev, E., Kazantsev, A., Kebschull, U., Keidel, R., Khan, M.M., Khan, P., Khanzadeev, A., Kharlov, Y., Kileng, B., Kim, D.J., Kim, D.S., Kim, D.W., Kim, J.H., Kim, J.S., Kim, M., Kim, S., Kim, S.H., Kirsch, S., Kisel, I., Kiselev, S., Kisiel, A., Klay, J.L., Klein, J., Klein-Bösing, C., Kliemant, M., Kluge, A., Knichel, M.L., Koch, K., Köhler, M.K., Kolojvari, A., Kondratiev, V., Kondratyeva, N., Konevskih, A., Kornaś, E., Kottachchi Kankanamge Don, C., Kour, R., Kowalski, M., Kox, S., Koyithatta Meethaleveedu, G., Kozlov, K., Kral, J., Králik, I., Kramer, F., Kraus, I., Krawutschke, T., Kretz, M., Krivda, M., Krizek, F., Krus, M., Kryshen, E., Krzewicki, M., Kucheriaev, Y., Kuhn, C., Kuijer, P.G., Kurashvili, P., Kurepin, A., Kurepin, A.B., Kuryakin, A., Kushpil, S., Kushpil, V., Kweon, M.J., Kwon, Y., La Rocca, P., Ladrón de Guevara, P., Lafage, V., Lakomov, I., Lara, C., Larsen, D.T., Lazzeroni, C., Le Bornec, Y., Lea, R., Lechman, M., Lee, K.S., Lee, S.C., Lefèvre, F., Lehnert, J., Leistam, L., Lenhardt, M., Lenti, V., León Monzón, I., León Vargas, H., Lévai, P., Li, X., Lietava, R., Lindal, S., Lindenstruth, V., Lippmann, C., Lisa, M.A., Liu, L., Loggins, V.R., Loginov, V., Lohn, S., Lohner, D., Loizides, C., Loo, K.K., Lopez, X., López Noriega, M., López Torres, E., Løvhøiden, G., Lu, X.-G., Luettig, P., Lunardon, M., Luparello, G., Luquin, L., Luzzi, C., Ma, K., Ma, R., Madagodahettige-Don, D.M., Maevskaya, A., Mager, M., Mahapatra, D.P., Maire, A., Malaev, M., Maldonado Cervantes, I., MalʼKevich, D., Malzacher, P., Mamonov, A., Manceau, L., Manko, V., 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Published: 2012
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44. Erratum to 'Rapidity and transverse momentum dependence of inclusive J/ψ production in pp collisions at √s=7 TeV' [Phys. Lett. B 704 (5) (2011) 442]

Author: Aamodt, K., Abrahantes Quintana, A., Adamová, D., Adare, A.M., Aggarwal, M.M., Aglieri Rinella, G., Agocs, A.G., Agostinelli, A., Aguilar Salazar, S., Ahammed, Z., Ahmad, N., Ahmad Masoodi, A., Ahn, S.U., Akindinov, A., Aleksandrov, D., Alessandro, B., Alfaro Molina, R., Alici, A., Alkin, A., Almaráz Aviña, E., Alme, J., Alt, T., Altini, V., Altsybeev, I., Andrei, C., Andronic, A., Anguelov, V., Anson, C., Antičić, T., Antinori, F., Antonioli, P., Aphecetche, L., Appelshäuser, H., Arbor, N., Arcelli, S., Arend, A., Armesto, N., Arnaldi, R., Aronsson, T., Arsene, I.C., Asryan, A., Augustinus, A., Averbeck, R., Awes, T.C., Äystö, J., Azmi, M.D., Bach, M., Badalà, A., Baek, Y.W., Bailhache, R., Bala, R., Baldini Ferroli, R., Baldisseri, A., Baldit, A., Bán, J., Barbera, R., Barile, F., Barnaföldi, G.G., Barnby, L.S., Barret, V., Bartke, J., Basile, M., Bastid, N., Bathen, B., Batigne, G., Batyunya, B., Baumann, C., Bearden, I.G., Beck, H., Belikov, I., Bellini, F., Bellwied, R., Belmont-Moreno, E., Beole, S., Berceanu, I., Bercuci, A., Berdermann, E., Berdnikov, Y., Bergmann, C., Betev, L., Bhasin, A., Bhati, A.K., Bianchi, L., Bianchi, N., Bianchin, C., Bielčík, J., Bielčíková, J., Bilandzic, A., Biolcati, E., Blanc, A., Blanco, F., Blau, D., Blume, C., Bock, N., Bogdanov, A., Bøggild, H., Bogolyubsky, M., Boldizsár, L., Bombara, M., Bombonati, C., Book, J., Borel, H., Borissov, A., Bortolin, C., Bose, S., Bossú, F., Botje, M., Böttger, S., Boyer, B., Braun-Munzinger, P., Bravina, L., Bregant, M., Breitner, T., Broz, M., Brun, R., Bruna, E., Bruno, G.E., Budnikov, D., Buesching, H., Bufalino, S., Busch, O., Buthelezi, Z., Caffarri, D., Cai, X., Caines, H., Calvo Villar, E., Camerini, P., Canoa Roman, V., Cara Romeo, G., Carena, F., Carena, W., Carminati, F., Casanova Díaz, A., Caselle, M., Castillo Castellanos, J., Catanescu, V., Cavicchioli, C., Cepila, J., Cerello, P., Chang, B., Chapeland, S., Charvet, J.L., Chattopadhyay, S., Cherney, M., Cheshkov, C., 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Nilsen, B.S., Nilsson, M.S., Noferini, F., Nooren, G., Novitzky, N., Nyanin, A., Nyatha, A., Nygaard, C., Nystrand, J., Obayashi, H., Ochirov, A., Oeschler, H., Oh, S.K., Oleniacz, J., Oppedisano, C., Ortiz Velasquez, A., Ortona, G., Oskarsson, A., Ostrowski, P., Otterlund, I., Otwinowski, J., Øvrebekk, G., Oyama, K., Ozawa, K., Pachmayer, Y., Pachr, M., Padilla, F., Pagano, P., Paić, G., Painke, F., Pajares, C., Pal, S., Pal, S.K., Palaha, A., Palmeri, A., Pappalardo, G.S., Park, W.J., Paticchio, V., Pavlinov, A., Pawlak, T., Peitzmann, T., Peresunko, D., Pérez Lara, C.E., Perini, D., Perrino, D., Peryt, W., Pesci, A., Peskov, V., Pestov, Y., Peters, A.J., Petráček, V., Petran, M., Petris, M., Petrov, P., Petrovici, M., Petta, C., Piano, S., Piccotti, A., Pikna, M., Pillot, P., Pinazza, O., Pinsky, L., Pitz, N., Piuz, F., Piyarathna, D.B., Platt, R., Płoskoń, M., Pluta, J., Pocheptsov, T., Pochybova, S., Podesta-Lerma, P.L.M., Poghosyan, M.G., Polichtchouk, B., Pop, A., Pospíšil, V., Potukuchi, B., Prasad, S.K., Preghenella, R., Prino, F., Pruneau, C.A., Pshenichnov, I., Puddu, G., Pulvirenti, A., Punin, V., Putiš, M., Putschke, J., Quercigh, E., Qvigstad, H., Rachevski, A., Rademakers, A., Radomski, S., Räihä, T.S., Rak, J., Rakotozafindrabe, A., Ramello, L., Ramírez Reyes, A., Rammler, M., Raniwala, R., Raniwala, S., Räsänen, S.S., Rathee, D., Read, K.F., Real, J.S., Redlich, K., Renfordt, R., Reolon, A.R., Reshetin, A., Rettig, F., Revol, J.-P., Reygers, K., Ricaud, H., Riccati, L., Ricci, R.A., Richter, M., Riedler, P., Riegler, W., Riggi, F., Rodríguez Cahuantzi, M., Rohr, D., Röhrich, D., Romita, R., Ronchetti, F., Rosinský, P., Rosnet, P., Rossegger, S., Rossi, A., Roukoutakis, F., Rousseau, S., Roy, C., Roy, P., Rubio Montero, A.J., Rui, R., Ryabinkin, E., Rybicki, A., Sadovsky, S., Šafařík, K., Sahoo, R., Sahu, P.K., Saiz, P., Sakai, S., Sakata, D., Salgado, C.A., Sambyal, S., Samsonov, V., Šándor, L., Sandoval, A., Sano, M., Sano, S., Santo, R., Santoro, R., Sarkamo, J., Saturnini, P., Scapparone, E., Scarlassara, F., Scharenberg, R.P., Schiaua, C., Schicker, R., Schmidt, C., Schmidt, H.R., Schreiner, S., Schuchmann, S., Schukraft, J., Schutz, Y., Schwarz, K., Schweda, K., Scioli, G., Scomparin, E., Scott, P.A., Scott, R., Segato, G., Senyukov, S., Seo, J., Serci, S., Serradilla, E., Sevcenco, A., Sgura, I., Shabratova, G., Shahoyan, R., Sharma, N., Sharma, S., Shigaki, K., Shimomura, M., Shtejer, K., Sibiriak, Y., Siciliano, M., Sicking, E., Siemiarczuk, T., Silvermyr, D., Simonetti, G., Singaraju, R., Singh, R., Singha, S., Sinha, B.C., Sinha, T., Sitar, B., Sitta, M., Skaali, T.B., Skjerdal, K., Smakal, R., Smirnov, N., Snellings, R., Søgaard, C., Soltz, R., Son, H., Song, J., Song, M., Soos, C., Soramel, F., Spyropoulou-Stassinaki, M., Srivastava, B.K., Stachel, J., Stan, I., Stefanek, G., Stefanini, G., Steinbeck, T., Steinpreis, M., Stenlund, E., Steyn, G., Stocco, D., Stock, R., Stokkevag, C.H., Stolpovskiy, M., Strmen, P., Suaide, A.A.P., Subieta Vásquez, M.A., Sugitate, T., Suire, C., Sukhorukov, M., Šumbera, M., Susa, T., Swoboda, D., Symons, T.J.M., Szanto de Toledo, A., Szarka, I., Szostak, A., Tagridis, C., Takahashi, J., Tapia Takaki, J.D., Tauro, A., Tejeda Muñoz, G., Telesca, A., Terrevoli, C., Thäder, J., Thomas, D., Thomas, J.H., Tieulent, R., Timmins, A.R., Tlusty, D., Toia, A., Torii, H., Tosello, F., Traczyk, T., Truesdale, D., Trzaska, W.H., Tumkin, A., Turrisi, R., Turvey, A.J., Tveter, T.S., Ulery, J., Ullaland, K., Uras, A., Urbán, J., Urciuoli, G.M., Usai, G.L., Vajzer, M., Vala, M., Valencia Palomo, L., Vallero, S., van der Kolk, N., van Leeuwen, M., Vande Vyvre, P., Vannucci, L., Vargas, A., Varma, R., Vasileiou, M., Vasiliev, A., Vechernin, V., Veldhoen, M., Venaruzzo, M., Vercellin, E., Vergara, S., Vernekohl, D.C., Vernet, R., Verweij, M., Vickovic, L., Viesti, G., Vikhlyantsev, O., Vilakazi, Z., Villalobos Baillie, O., Vinogradov, A., Vinogradov, L., Vinogradov, Y., Virgili, T., Viyogi, Y.P., Vodopyanov, A., Voloshin, K., Voloshin, S., Volpe, G., von Haller, B., Vranic, D., Vrláková, J., Vulpescu, B., Vyushin, A., Wagner, B., Wagner, V., Wan, R., Wang, D., Wang, M., Wang, Y., Watanabe, K., Wessels, J.P., Westerhoff, U., Wiechula, J., Wikne, J., Wilde, M., Wilk, A., Wilk, G., Williams, M.C.S., Windelband, B., Yang, H., Yasnopolskiy, S., Yi, J., Yin, Z., Yokoyama, H., Yoo, I.-K., Yuan, X., Yushmanov, I., Zabrodin, E., Zach, C., Zampolli, C., Zaporozhets, S., Zarochentsev, A., Závada, P., Zaviyalov, N., Zbroszczyk, H., Zelnicek, P., Zenin, A., Zgura, I., Zhalov, M., Zhang, X., Zhou, D., Zhou, F., Zhou, Y., Zhu, X., Zichichi, A., Zinovjev, G., Zoccarato, Y., and Zynovyev, M.
Subjects: Nuclear and High Energy Physics
Published: 2012

45. Femtoscopy of pp collisions at $\sqrt{s}$=0.9 and 7 TeV at the LHC with two-pion Bose-Einstein correlations

Author: Aamodt, K., Abrahantes Quintana, A., Adamova, D., Adare, A.M., Aggarwal, M.M., Aglieri Rinella, G., Agocs, A.G., Aguilar Salazar, S., Ahammed, Z., Ahmad, N., Masoodi, A.Ahmad, Ahn, S.U., Akindinov, A., Aleksandrov, D., Alessandro, B., Molina, R.Alfaro, Alici, A., Alkin, A., Almaraz Avina, E., Alt, T., Altini, V., Altinpinar, S., Altsybeev, I., Andrei, C., Andronic, A., Anguelov, V., Anson, C., Anticic, T., Antinori, F., Antonioli, P., Aphecetche, L., Appelshauser, H., Arbor, N., Arcelli, S., Arend, A., Armesto, N., Arnaldi, R., Aronsson, T., Arsene, I.C., Asryan, A., Augustinus, A., Averbeck, R., Awes, T.C., Aysto, J., Azmi, M.D., Bach, M., Badala, A., Baek, Y.W., Bagnasco, S., Bailhache, R., Bala, R., Ferroli, R.Baldini, Baldisseri, A., Baldit, A., Ban, J., Barbera, R., Barile, F., Barnafoldi, G.G., Barnby, L.S., Barret, V., Bartke, J., Basile, M., Bastid, N., Bathen, B., Batigne, G., Batyunya, B., Baumann, C., Bearden, I.G., Beck, H., Belikov, I., Bellini, F., Bellwied, R., Belmont-Moreno, E., Beole, S., Berceanu, I., Bercuci, A., Berdermann, E., Berdnikov, Y., Betev, L., Bhasin, A., Bhati, A.K., Bianchi, L., Bianchi, N., Bianchin, C., Bielcik, J., Bielcikova, J., Bilandzic, A., Biolcati, E., Blanc, A., Blanco, F., Blau, D., Blume, C., Boccioli, M., Bock, N., Bogdanov, A., Boggild, H., Bogolyubsky, M., Boldizsar, L., Bombara, M., Bombonati, C., Book, J., Borel, H., Bortolin, C., Bose, S., Bossu, F., Botje, M., Bottger, S., Boyer, B., Braun-Munzinger, P., Bravina, L., Bregant, M., Breitner, T., Broz, M., Brun, R., Bruna, E., Bruno, G.E., Budnikov, D., Buesching, H., Busch, O., Buthelezi, Z., Caffarri, D., Cai, X., Caines, H., Calvo Villar, E., Camerini, P., Canoa Roman, V., Cara Romeo, G., Carena, F., Carena, W., Carminati, F., Casanova Diaz, A., Caselle, M., Castillo Castellanos, J., Catanescu, V., Cavicchioli, C., Cerello, P., Chang, B., Chapeland, S., Charvet, J.L., Chattopadhyay, S., Cherney, M., Cheshkov, C., Cheynis, B., Chiavassa, E., Chibante Barroso, V., Chinellato, D.D., Chochula, P., Chojnacki, M., Christakoglou, P., Christensen, C.H., Christiansen, P., Chujo, T., Cicalo, C., Cifarelli, L., Cindolo, F., Cleymans, J., Coccetti, F., Coffin, J.P., Coli, S., Conesa Balbastre, G., Conesa del Valle, Z., Constantin, P., Contin, G., Contreras, J.G., Cormier, T.M., Corrales Morales, Y., Cortes Maldonado, I., Cortese, P., Cosentino, M.R., Costa, F., Cotallo, M.E., Crescio, E., Crochet, P., Cuautle, E., Cunqueiro, L., Erasmo, G.D., Dainese, A., Dalsgaard, H.H., Danu, A., Das, D., Das, I., Dash, A., Dash, S., De, S., De Azevedo Moregula, A., de Barros, G.O.V., De Caro, A., De Cataldo, G., de Cuveland, J., De Falco, A., De Gruttola, D., De Marco, N., De Pasquale, S., De Remigis, R., de Rooij, R., Delagrange, H., Delgado Mercado, Y., Dellacasa, G., Deloff, A., Demanov, V., Denes, E., Deppman, A., Di Bari, D., Di Giglio, C., Di Liberto, S., Di Mauro, A., Di Nezza, P., Dietel, T., Divia, R., Djuvsland, O., Dobrin, A., Dobrowolski, T., Dominguez, I., Donigus, B., Dordic, O., Driga, O., Dubey, A.K., Ducroux, L., Dupieux, P., Dutta Majumdar, A.K., Dutta Majumdar, M.R., Elia, D., Emschermann, D., Engel, H., Erdal, H.A., Espagnon, B., Estienne, M., Esumi, S., Evans, D., Evrard, S., Eyyubova, G., Fabjan, C.W., Fabris, D., Faivre, J., Falchieri, D., Fantoni, A., Fasel, M., Fearick, R., Fedunov, A., Fehlker, D., Fekete, V., Felea, D., Feofilov, G., Fernandez Tellez, A., Ferretti, A., Ferretti, R., Figueredo, M.A.S., Filchagin, S., Fini, R., Finogeev, D., Fionda, F.M., Fiore, E.M., Floris, M., Foertsch, S., Foka, P., Fokin, S., Fragiacomo, E., Fragkiadakis, M., Frankenfeld, U., Fuchs, U., Furano, F., Furget, C., Fusco Girard, M., Gaardhoje, J.J., Gadrat, S., Gagliardi, M., Gago, A., Gallio, M., Ganoti, P., Garabatos, C., Gemme, R., Gerhard, J., Germain, M., Geuna, C., Gheata, A., Gheata, M., Ghidini, B., Ghosh, P., Girard, M.R., Giraudo, G., Giubellino, P., Gladysz-Dziadus, E., Glassel, P., Gomez, R., Gonzalez-Trueba, L.H., Gonzalez-Zamora, P., Gonzalez Santos, H., Gorbunov, S., Gotovac, S., Grabski, V., Graczykowski, L.K., Grajcarek, R., Grelli, A., Grigoras, A., Grigoras, C., Grigoriev, V., Grigoryan, A., Grigoryan, S., Grinyov, B., Grion, N., Gros, P., Grosse-Oetringhaus, J.F., Grossiord, J.Y., Grosso, R., Guber, F., Guernane, R., Guerra Gutierrez, C., Guerzoni, B., Gulbrandsen, K., Gulkanyan, H., Gunji, T., Gupta, A., Gupta, R., Gutbrod, H., Haaland, O., Hadjidakis, C., Haiduc, M., Hamagaki, H., Hamar, G., Harris, J.W., Hartig, M., Hasch, D., Hasegan, D., Hatzifotiadou, D., Hayrapetyan, A., Heide, M., Heinz, M., Helstrup, H., Herghelegiu, A., Hernandez, C., Herrera Corral, G., Herrmann, N., Hetland, K.F., Hicks, B., Hille, P.T., Hippolyte, B., Horaguchi, T., Hori, Y., Hristov, P., Hrivnacova, I., Huang, M., Huber, S., Humanic, T.J., Hwang, D.S., Ichou, R., Ilkaev, R., Ilkiv, I., Inaba, M., Incani, E., Innocenti, G.M., Innocenti, P.G., Ippolitov, M., Irfan, M., Ivan, C., Ivanov, A., Ivanov, M., Ivanov, V., Jacholkowski, A., Jacobs, P.M., Jancurova, L., Jangal, S., Janik, M.A., Janik, R., Jayarathna, S.P., Jena, S., Jirden, L., Jones, G.T., Jones, P.G., Jovanovic, P., Jung, H., Jung, W., Jusko, A., Kalcher, S., Kalinak, P., Kalisky, M., Kalliokoski, T., Kalweit, A., Kamermans, R., Kanaki, K., Kang, E., Kang, J.H., Kaplin, V., Karavichev, O., Karavicheva, T., Karpechev, E., Kazantsev, A., Kebschull, U., Keidel, R., Khan, M.M., Khanzadeev, A., Kharlov, Y., Kileng, B., Kim, D.J., Kim, D.S., Kim, D.W., Kim, H.N., Kim, J.H., Kim, J.S., Kim, M., Kim, S., Kim, S.H., Kirsch, S., Kisel, I., Kiselev, S., Kisiel, A., Klay, J.L., Klein, J., Klein-Bosing, C., Kliemant, M., Klovning, A., Kluge, A., Knichel, M.L., Koch, K., Kohler, M.K., Kolevatov, R., Kolojvari, A., Kondratiev, V., Kondratyeva, N., Konevskih, A., Kornas, E., Kottachchi Kankanamge Don, C., Kour, R., Kowalski, M., Kox, S., Koyithatta Meethaleveedu, G., Kozlov, K., Kral, J., Kralik, I., Kramer, F., Kraus, I., Krawutschke, T., Kretz, M., Krivda, M., Krumbhorn, D., Krus, M., Kryshen, E., Krzewicki, M., Kucheriaev, Y., Kuhn, C., Kuijer, P.G., Kurashvili, P., Kurepin, A., Kurepin, A.B., Kuryakin, A., Kushpil, S., Kushpil, V., Kweon, M.J., Kwon, Y., La Rocca, P., Ladron de Guevara, P., Lafage, V., Lara, C., Larsen, D.T., Lazzeroni, C., Le Bornec, Y., Lea, R., Lee, K.S., Lee, S.C., Lefevre, F., Lehnert, J., Leistam, L., Lenhardt, M., Lenti, V., Leon Monzon, I., Leon Vargas, H., Levai, P., Li, X., Lietava, R., Lindal, S., Lindenstruth, V., Lippmann, C., Lisa, M.A., Liu, L., Loggins, V.R., Loginov, V., Lohn, S., Lohner, D., Loizides, C., Lopez, X., Lopez Noriega, M., Lopez Torres, E., Lovhoiden, G., Lu, X.G., Luettig, P., Lunardon, M., Luparello, G., Luquin, L., Luzzi, C., Ma, K., Ma, R., Madagodahettige-Don, D.M., Maevskaya, A., Mager, M., Mahapatra, D.P., Maire, A., Malaev, M., Maldonado Cervantes, I., Malinina, L., Mal'Kevich, D., Malzacher, P., Mamonov, A., Manceau, L., Mangotra, L., Manko, V., Manso, F., Manzari, V., Mao, Y., Mares, J., Margagliotti, G.V., Margotti, A., Marin, A., Martashvili, I., Martinengo, P., Martinez, M.I., Martinez Davalos, A., Martinez Garcia, G., Martynov, Y., Mas, A., Masciocchi, S., Masera, M., Masoni, A., Massacrier, L., Mastromarco, M., Mastroserio, A., Matthews, Z.L., Matyja, A., Mayani, D., Mazza, G., Mazzoni, M.A., Meddi, F., Menchaca-Rocha, A., Mendez Lorenzo, P., Mercado Perez, J., Mereu, P., Miake, Y., Midori, J., Milano, L., Milosevic, J., Mischke, A., Miskowiec, D., Mitu, C., Mlynarz, J., Mohanty, B., Molnar, L., Montano Zetina, L., Monteno, M., Montes, E., Morando, M., Moreira De Godoy, D.A., Moretto, S., Morsch, A., Muccifora, V., Mudnic, E., Muller, H., Muhuri, S., Munhoz, M.G., Munoz, J., Musa, L., Musso, A., Nandi, B.K., Nania, R., Nappi, E., Nattrass, C., Navach, F., Navin, S., Nayak, T.K., Nazarenko, S., Nazarov, G., Nedosekin, A., Nendaz, F., Newby, J., Nicassio, M., Nielsen, B.S., Nikolaev, S., Nikolic, V., Nikulin, S., Nikulin, V., Nilsen, B.S., Nilsson, M.S., Noferini, F., Nooren, G., Novitzky, N., Nyanin, A., Nyatha, A., Nygaard, C., Nystrand, J., Obayashi, H., Ochirov, A., Oeschler, H., Oh, S.K., Oleniacz, J., Oppedisano, C., Ortiz Velasquez, A., Ortona, G., Oskarsson, A., Ostrowski, P., Otterlund, I., Otwinowski, J., Ovrebekk, G., Oyama, K., Ozawa, K., Pachmayer, Y., Pachr, M., Padilla, F., Pagano, P., Paic, G., Painke, F., Pajares, C., Pal, S., Pal, S.K., Palaha, A., Palmeri, A., Pappalardo, G.S., Park, W.J., Paticchio, V., Pavlinov, A., Pawlak, T., Peitzmann, T., Peresunko, D., Perez Lara, C.E., Perini, D., Perrino, D., Peryt, W., Pesci, A., Peskov, V., Pestov, Y., Peters, A.J., Petracek, V., Petris, M., Petrov, P., Petrovici, M., Petta, C., Piano, S., Piccotti, A., Pikna, M., Pillot, P., Pinazza, O., Pinsky, L., Pitz, N., Piuz, F., Piyarathna, D.B., Platt, R., Ploskon, M., Pluta, J., Pocheptsov, T., Pochybova, S., Podesta-Lerma, P.L.M., Poghosyan, M.G., Polak, K., Polichtchouk, B., Pop, A., Pospisil, V., Potukuchi, B., Prasad, S.K., Preghenella, R., Prino, F., Pruneau, C.A., Pshenichnov, I., Puddu, G., Pulvirenti, A., Punin, V., Putis, M., Putschke, J., Quercigh, E., Qvigstad, H., Rachevski, A., Rademakers, A., Rademakers, O., Radomski, S., Raiha, T.S., Rak, J., Rakotozafindrabe, A., Ramello, L., Ramirez Reyes, A., Rammler, M., Raniwala, R., Raniwala, S., Rasanen, S.S., Read, K.F., Real, J.S., Redlich, K., Renfordt, R., Reolon, A.R., Reshetin, A., Rettig, F., Revol, J.P., Reygers, K., Ricaud, H., Riccati, L., Ricci, R.A., Richter, M., Riedler, P., Riegler, W., Riggi, F., Rivetti, A., Rodriguez Cahuantzi, M., Rohr, D., Rohrich, D., Romita, R., Ronchetti, F., Rosinsky, P., Rosnet, P., Rossegger, S., Rossi, A., Roukoutakis, F., Rousseau, S., Roy, C., Roy, P., Rubio Montero, A.J., Rui, R., Rusanov, I., Ryabinkin, E., Rybicki, A., Sadovsky, S., Safarik, K., Sahoo, R., Sahu, P.K., Saiz, P., Sakai, S., Sakata, D., Salgado, C.A., Samanta, T., Sambyal, S., Samsonov, V., Sandor, L., Sandoval, A., Sano, M., Sano, S., Santo, R., Santoro, R., Sarkamo, J., Saturnini, P., Scapparone, E., Scarlassara, F., Scharenberg, R.P., Schiaua, C., Schicker, R., Schmidt, C., Schmidt, H.R., Schreiner, S., Schuchmann, S., Schukraft, J., Schutz, Y., Schwarz, K., Schweda, K., Scioli, G., Scomparin, E., Scott, P.A., Scott, R., Segato, G., Senyukov, S., Seo, J., Serci, S., Serradilla, E., Sevcenco, A., Shabratova, G., Shahoyan, R., Sharma, N., Sharma, S., Shigaki, K., Shimomura, M., Shtejer, K., Sibiriak, Y., Siciliano, M., Sicking, E., Siemiarczuk, T., Silenzi, A., Silvermyr, D., Simonetti, G., Singaraju, R., Singh, R., Sinha, B.C., Sinha, T., Sitar, B., Sitta, M., Skaali, T.B., Skjerdal, K., Smakal, R., Smirnov, N., Snellings, R., Sogaard, C., Soloviev, A., Soltz, R., Son, H., Song, M., Soos, C., Soramel, F., Spyropoulou-Stassinaki, M., Srivastava, B.K., Stachel, J., Stan, I., Stefanek, G., Stefanini, G., Steinbeck, T., Stenlund, E., Steyn, G., Stocco, D., Stock, R., Stolpovskiy, M., Strmen, P., Suaide, A.A.P., Subieta Vasquez, M.A., Sugitate, T., Suire, C., Sumbera, M., Susa, T., Swoboda, D., Symons, T.J.M., Szanto de Toledo, A., Szarka, I., Szostak, A., Tagridis, C., Takahashi, J., J.Tapia Takaki, D., Tauro, A., Tavlet, M., Tejeda Munoz, G., Telesca, A., Terrevoli, C., Thader, J., Thomas, D., Thomas, J.H., Tieulent, R., Timmins, A.R., Tlusty, D., Toia, A., Torii, H., Toscano, L., Tosello, F., Traczyk, T., Truesdale, D., Trzaska, W.H., Tumkin, A., Turrisi, R., Turvey, A.J., Tveter, T.S., Ulery, J., Ullaland, K., Uras, A., Urban, J., Urciuoli, G.M., Usai, G.L., Vacchi, A., Vala, M., Valencia Palomo, L., Vallero, S., van der Kolk, N., van Leeuwen, M., Vande Vyvre, P., Vannucci, L., Vargas, A., Varma, R., Vasileiou, M., Vasiliev, A., Vechernin, V., Venaruzzo, M., Vercellin, E., Vergara, S., Vernet, R., Verweij, M., Vickovic, L., Viesti, G., Vikhlyantsev, O., Vilakazi, Z., Villalobos Baillie, O., Vinogradov, A., Vinogradov, L., Vinogradov, Y., Virgili, T., Viyogi, Y.P., Vodopyanov, A., Voloshin, K., Voloshin, S., Volpe, G., von Haller, B., Vranic, D., Vrlakova, J., Vulpescu, B., Wagner, B., Wagner, V., Wan, R., Wang, D., Wang, Y., Watanabe, K., Wessels, J.P., Westerhoff, U., Wiechula, J., Wikne, J., Wilde, M., Wilk, A., Wilk, G., Williams, M.C.S., Windelband, B., Yang, H., Yasnopolskiy, S., Yi, J., Yin, Z., Yokoyama, H., Yoo, I.K., Yuan, X., Yushmanov, I., Zabrodin, E., Zampolli, C., Zaporozhets, S., Zarochentsev, A., Zavada, P., Zbroszczyk, H., Zelnicek, P., Zenin, A., Zgura, I., Zhalov, M., Zhang, X., Zhou, D., Zhu, X., Zichichi, A., Zinovjev, G., Zoccarato, Y., Zynovyev, M., Universidade Estadual de Campinas, Laboratoire de Physique Corpusculaire, Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire SUBATECH Nantes (SUBATECH), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Nantes (UN)-Mines Nantes (Mines Nantes), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, ALICE, Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre de Calcul de l'IN2P3 (CC-IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Mines Nantes (Mines Nantes)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Pion Interferometry, High Energy Physics - Experiment (hep-ex), Heavy-ion Collisions, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], FOS: Physical sciences, Nuclear Experiment (nucl-ex), [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], Nuclear Experiment, Particle Physics - Experiment, Energies, High Energy Physics - Experiment
Abstract: We report on the high statistics two-pion correlation functions from pp collisions at $\sqrt{s}=0.9$ TeV and $\sqrt{s}$=7 TeV, measured by the ALICE experiment at the Large Hadron Collider. The correlation functions as well as the extracted source radii scale with event multiplicity and pair momentum. When analyzed in the same multiplicity and pair transverse momentum range, the correlation is similar at the two collision energies. A three-dimensional femtoscopic analysis shows an increase of the emission zone with increasing event multiplicity as well as decreasing homogeneity lengths with increasing transverse momentum. The latter trend gets more pronounced as multiplicity increases. This suggests the development of space-momentum correlations, at least for collisions producing a high multiplicity of particles. We consider these trends in the context of previous femtoscopic studies in high-energy hadron and heavy-ion collisions, and discuss possible underlying physics mechanisms. Detailed analysis of the correlation reveals an exponential shape in the outward and longitudinal directions, while the sideward remains a Gaussian. This is interpreted as a result of a significant contribution of strongly decaying resonances to the emission region shape. Significant non-femtoscopic correlations are observed, and are argued to be the consequence of "mini-jet"-like structures extending to low $p_{\rm T}$. They are well reproduced by the Monte-Carlo generators and seen also in $\pi^+\pi^-$ correlations., Comment: 21 pages, 18 captioned figures, 5 tables, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/3872
Published: 2011
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46. Rapidity and transverse momentum dependence of inclusive J/psi production in pp collisions at √s=7 TeV

Author: Aamodt, K., Abrahantes Quintana, A., Adamová, D., Adare, A.M., Aggarwal, M.M., Aglieri Rinella, G., Agocs, A.G., Agostinelli, A., Aguilar Salazar, S., Ahammed, Z., Ahmad, N., Ahmad Masoodi, A., Ahn, S.U., Akindinov, A., Aleksandrov, D., Alessandro, B., Alfaro Molina, R., Alici, A., Alkin, A., Almaráz Aviña, E., Alme, J., Alt, T., Altini, V., Altsybeev, I., Andrei, C., Andronic, A., Anguelov, V., Anson, C., Antičić, T., Antinori, F., Antonioli, P., Aphecetche, L., Appelshäuser, H., Arbor, N., Arcelli, S., Arend, A., Armesto, N., Arnaldi, R., Aronsson, T., Arsene, I.C., Asryan, A., Augustinus, A., Averbeck, R., Awes, T.C., Äystö, J., Azmi, M.D., Bach, M., Badalà, A., Baek, Y.W., Bailhache, R., Bala, R., Baldini Ferroli, R., Baldisseri, A., Baldit, A., Bán, J., Barbera, R., Barile, F., Barnaföldi, G.G., Barnby, L.S., Barret, V., Bartke, J., Basile, M., Bastid, N., Bathen, B., Batigne, G., Batyunya, B., Baumann, C., Bearden, I.G., Beck, H., Belikov, I., Bellini, F., Bellwied, R., Belmont-Moreno, E., Beole, S., Berceanu, I., Bercuci, A., Berdermann, E., Berdnikov, Y., Bergmann, C., Betev, L., Bhasin, A., Bhati, A.K., Bianchi, L., Bianchi, N., Bianchin, C., Bielčík, J., Bielčíková, J., Bilandzic, A., Biolcati, E., Blanc, A., Blanco, F., Blau, D., Blume, C., Bock, N., Bogdanov, A., Bøggild, H., Bogolyubsky, M., Boldizsár, L., Bombara, M., Bombonati, C., Book, J., Borel, H., Borissov, A., Bortolin, C., Bose, S., Bossú, F., Botje, M., Böttger, S., Boyer, B., Braun-Munzinger, P., Bravina, L., Bregant, M., Breitner, T., Broz, M., Brun, R., Bruna, E., Bruno, G.E., Budnikov, D., Buesching, H., Bufalino, S., Busch, O., Buthelezi, Z., Caffarri, D., Cai, X., Caines, H., Calvo Villar, E., Camerini, P., Canoa Roman, V., Cara Romeo, G., Carena, F., Carena, W., Carminati, F., Casanova Díaz, A., Caselle, M., Castillo Castellanos, J., Catanescu, V., Cavicchioli, C., Cepila, J., Cerello, P., Chang, B., Chapeland, S., Charvet, J.L., Chattopadhyay, S., Cherney, M., Cheshkov, C., Cheynis, B., Chiavassa, E., Chibante Barroso, V., Chinellato, D.D., Chochula, P., Chojnacki, M., Christakoglou, P., Christensen, C.H., Christiansen, P., Chujo, T., Cicalo, C., Cifarelli, L., Cindolo, F., Cleymans, J., Coccetti, F., Coffin, J.-P., Conesa Balbastre, G., Conesa del Valle, Z., Constantin, P., Contin, G., Contreras, J.G., Cormier, T.M., Corrales Morales, Y., Cortés Maldonado, I., Cortese, P., Cosentino, M.R., Costa, F., Cotallo, M.E., Crescio, E., Crochet, P., Cuautle, E., Cunqueiro, L., D Erasmo, G., Dainese, A., Dalsgaard, H.H., Danu, A., Das, D., Das, I., Dash, A., Dash, S., De, S., De Azevedo Moregula, A., de Barros, G.O.V., De Caro, A., de Cataldo, G., de Cuveland, J., De Falco, A., De Gruttola, D., De Marco, N., De Pasquale, S., de Rooij, R., Del Castillo Sanchez, E., Delagrange, H., Delgado Mercado, Y., Dellacasa, G., Deloff, A., Demanov, V., Dénes, E., Deppman, A., Di Bari, D., Di Giglio, C., Di Liberto, S., Di Mauro, A., Di Nezza, P., Dietel, T., Divià, R., Djuvsland, Ø., Dobrin, A., Dobrowolski, T., Domínguez, I., Dönigus, B., Dordic, O., Driga, O., Dubey, A.K., Ducroux, L., Dupieux, P., Dutta Majumdar, A.K., Dutta Majumdar, M.R., Elia, D., Emschermann, D., Engel, H., Erdal, H.A., Espagnon, B., Estienne, M., Esumi, S., Evans, D., Evrard, S., Eyyubova, G., Fabris, D., Faivre, J., Falchieri, D., Fantoni, A., Fasel, M., Fearick, R., Fedunov, A., Fehlker, D., Fekete, V., Felea, D., Feofilov, G., Fernández Téllez, A., Ferreiro, E.G., Ferretti, A., Ferretti, R., Figueredo, M.A.S., Filchagin, S., Fini, R., Finogeev, D., Fionda, F.M., Fiore, E.M., Floris, M., Foertsch, S., Foka, P., Fokin, S., Fragiacomo, E., Fragkiadakis, M., Frankenfeld, U., Fuchs, U., Furano, F., Furget, C., Fusco Girard, M., Gaardhøje, J.J., Gadrat, S., Gagliardi, M., Gago, A., Gallio, M., Ganoti, P., Garabatos, C., Garcia-Solis, E., Gemme, R., Gerhard, J., Germain, M., Geuna, C., Gheata, A., Gheata, M., Ghidini, B., Ghosh, P., Gianotti, P., Girard, M.R., Giubellino, P., Gladysz-Dziadus, E., Glässel, P., Gomez, R., González-Trueba, L.H., González-Zamora, P., Gorbunov, S., Gotovac, S., Grabski, V., Graczykowski, L.K., Grajcarek, R., Grelli, A., Grigoras, A., Grigoras, C., Grigoriev, V., Grigoryan, A., Grigoryan, S., Grinyov, B., Grion, N., Gros, P., Grosse-Oetringhaus, J.F., Grossiord, J.-Y., Guber, F., Guernane, R., Guerra Gutierrez, C., Guerzoni, B., Gulbrandsen, K., Gulkanyan, H., Gunji, T., Gupta, A., Gupta, R., Gutbrod, H., Haaland, Ø., Hadjidakis, C., Haiduc, M., Hamagaki, H., Hamar, G., Hanratty, L.D., Harmanova, Z., Harris, J.W., Hartig, M., Hasegan, D., Hatzifotiadou, D., Hayrapetyan, A., Heide, M., Heinz, M., Helstrup, H., Herghelegiu, A., Herrera Corral, G., Herrmann, N., Hetland, K.F., Hicks, B., Hille, P.T., Hippolyte, B., Horaguchi, T., Hori, Y., Hristov, P., Hřivnáčová, I., Huang, M., Huber, S., Humanic, T.J., Hwang, D.S., Ilkaev, R., Ilkiv, I., Inaba, M., Incani, E., Innocenti, G.M., Ippolitov, M., Irfan, M., Ivan, C., Ivanov, A., Ivanov, M., Ivanov, V., Jachołkowski, A., Jacobs, P.M., Jancurová, L., Jangal, S., Janik, M.A., Janik, R., Jayarathna, P.H.S.Y., Jena, S., Jirden, L., Jones, G.T., Jones, P.G., Jovanović, P., Jung, H., Jung, W., Jusko, A., Kalcher, S., Kaliňák, P., Kalisky, M., Kalliokoski, T., Kalweit, A., Kamermans, R., Kanaki, K., Kang, E., Kang, J.H., Kaplin, V., Karasu Uysal, A., Karavichev, O., Karavicheva, T., Karpechev, E., Kazantsev, A., Kebschull, U., Keidel, R., Khan, M.M., Khan, P., Khanzadeev, A., Kharlov, Y., Kileng, B., Kim, D.J., Kim, D.S., Kim, D.W., Kim, J.H., Kim, J.S., Kim, M., Kim, S., Kim, S.H., Kirsch, S., Kisel, I., Kiselev, S., Kisiel, A., Klay, J.L., Klein, J., Klein-Bösing, C., Kliemant, M., Kluge, A., Knichel, M.L., Koch, K., Köhler, M.K., Kolojvari, A., Kondratiev, V., Kondratyeva, N., Konevskih, A., Kornaś, E., Kottachchi Kankanamge Don, C., Kour, R., Kowalski, M., Kox, S., Koyithatta Meethaleveedu, G., Kozlov, K., Kral, J., Králik, I., Kramer, F., Kraus, I., Krawutschke, T., Kretz, M., Krivda, M., Krizek, F., Krus, M., Kryshen, E., Krzewicki, M., Kucheriaev, Y., Kuhn, C., Kuijer, P.G., Kurashvili, P., Kurepin, A., Kurepin, A.B., Kuryakin, A., Kushpil, S., Kushpil, V., Kweon, M.J., Kwon, Y., La Rocca, P., Ladrón de Guevara, P., Lafage, V., Lakomov, I., Lara, C., Larsen, D.T., Lazzeroni, C., Le Bornec, Y., Lea, R., Lechman, M., Lee, K.S., Lee, S.C., Lefèvre, F., Lehnert, J., Leistam, L., Lenhardt, M., Lenti, V., León Monzón, I., León Vargas, H., Lévai, P., Li, X., Lietava, R., Lindal, S., Lindenstruth, V., Lippmann, C., Lisa, M.A., Liu, L., Loggins, V.R., Loginov, V., Lohn, S., Lohner, D., Loizides, C., Loo, K.K., Lopez, X., López Noriega, M., López Torres, E., Løvhøiden, G., Lu, X.-G., Luettig, P., Lunardon, M., Luparello, G., Luquin, L., Luzzi, C., Ma, K., Ma, R., Madagodahettige-Don, D.M., Maevskaya, A., Mager, M., Mahapatra, D.P., Maire, A., Malaev, M., Maldonado Cervantes, I., MalʼKevich, D., Malzacher, P., Mamonov, A., Manceau, L., Manko, V., Manso, F., Manzari, V., Mao, Y., Marchisone, M., Mareš, J., Margagliotti, G.V., Margotti, A., Marín, A., Markert, C., Martashvili, I., Martinengo, P., Martínez, M.I., Martínez Davalos, A., Martínez García, G., Martynov, Y., Mas, A., Masciocchi, S., Masera, M., Masoni, A., Massacrier, L., Mastromarco, M., Mastroserio, A., Matthews, Z.L., Matyja, A., Mayani, D., Mazzoni, M.A., Meddi, F., Menchaca-Rocha, A., Mendez Lorenzo, P., Mercado Pérez, J., Meres, M., Miake, Y., Midori, J., Milano, L., Milosevic, J., Mischke, A., Miśkowiec, D., Mitu, C., Mlynarz, J., Mohanty, B., Molnar, L., Montaño Zetina, L., Monteno, M., Montes, E., Morando, M., Moreira De Godoy, D.A., Moretto, S., Morsch, A., Muccifora, V., Mudnic, E., Müller, H., Muhuri, S., Munhoz, M.G., Musa, L., Musso, A., Nandi, B.K., Nania, R., Nappi, E., Nattrass, C., Navach, F., Navin, S., Nayak, T.K., Nazarenko, S., Nazarov, G., Nedosekin, A., Nendaz, F., Nicassio, M., Nielsen, B.S., Nikolaev, S., Nikolic, V., Nikulin, S., Nikulin, V., Nilsen, B.S., Nilsson, M.S., Noferini, F., Nooren, G., Novitzky, N., Nyanin, A., Nyatha, A., Nygaard, C., Nystrand, J., Obayashi, H., Ochirov, A., Oeschler, H., Oh, S.K., Oleniacz, J., Oppedisano, C., Ortiz Velasquez, A., Ortona, G., Oskarsson, A., Ostrowski, P., Otterlund, I., Otwinowski, J., Øvrebekk, G., Oyama, K., Ozawa, K., Pachmayer, Y., Pachr, M., Padilla, F., Pagano, P., Paić, G., Painke, F., Pajares, C., Pal, S., Pal, S.K., Palaha, A., Palmeri, A., Pappalardo, G.S., Park, W.J., Paticchio, V., Pavlinov, A., Pawlak, T., Peitzmann, T., Peresunko, D., Pérez Lara, C.E., Perini, D., Perrino, D., Peryt, W., Pesci, A., Peskov, V., Pestov, Y., Peters, A.J., Petráček, V., Petran, M., Petris, M., Petrov, P., Petrovici, M., Petta, C., Piano, S., Piccotti, A., Pikna, M., Pillot, P., Pinazza, O., Pinsky, L., Pitz, N., Piuz, F., Piyarathna, D.B., Platt, R., Płoskoń, M., Pluta, J., Pocheptsov, T., Pochybova, S., Podesta-Lerma, P.L.M., Poghosyan, M.G., Polichtchouk, B., Pop, A., Pospíšil, V., Potukuchi, B., Prasad, S.K., Preghenella, R., Prino, F., Pruneau, C.A., Pshenichnov, I., Puddu, G., Pulvirenti, A., Punin, V., Putiš, M., Putschke, J., Quercigh, E., Qvigstad, H., Rachevski, A., Rademakers, A., Radomski, S., Räihä, T.S., Rak, J., Rakotozafindrabe, A., Ramello, L., Ramírez Reyes, A., Rammler, M., Raniwala, R., Raniwala, S., Räsänen, S.S., Rathee, D., Read, K.F., Real, J.S., Redlich, K., Renfordt, R., Reolon, A.R., Reshetin, A., Rettig, F., Revol, J.-P., Reygers, K., Ricaud, H., Riccati, L., Ricci, R.A., Richter, M., Riedler, P., Riegler, W., Riggi, F., Rodríguez Cahuantzi, M., Rohr, D., Röhrich, D., Romita, R., Ronchetti, F., Rosinský, P., Rosnet, P., Rossegger, S., Rossi, A., Roukoutakis, F., Rousseau, S., Roy, C., Roy, P., Rubio Montero, A.J., Rui, R., Ryabinkin, E., Rybicki, A., Sadovsky, S., Šafařík, K., Sahoo, R., Sahu, P.K., Saiz, P., Sakai, S., Sakata, D., Salgado, C.A., Sambyal, S., Samsonov, V., Šándor, L., Sandoval, A., Sano, M., Sano, S., Santo, R., Santoro, R., Sarkamo, J., Saturnini, P., Scapparone, E., Scarlassara, F., Scharenberg, R.P., Schiaua, C., Schicker, R., Schmidt, C., Schmidt, H.R., Schreiner, S., Schuchmann, S., Schukraft, J., Schutz, Y., Schwarz, K., Schweda, K., Scioli, G., Scomparin, E., Scott, P.A., Scott, R., Segato, G., Senyukov, S., Seo, J., Serci, S., Serradilla, E., Sevcenco, A., Sgura, I., Shabratova, G., Shahoyan, R., Sharma, N., Sharma, S., Shigaki, K., Shimomura, M., Shtejer, K., Sibiriak, Y., Siciliano, M., Sicking, E., Siemiarczuk, T., Silvermyr, D., Simonetti, G., Singaraju, R., Singh, R., Singha, S., Sinha, B.C., Sinha, T., Sitar, B., Sitta, M., Skaali, T.B., Skjerdal, K., Smakal, R., Smirnov, N., Snellings, R., Søgaard, C., Soltz, R., Son, H., Song, J., Song, M., Soos, C., Soramel, F., Spyropoulou-Stassinaki, M., Srivastava, B.K., Stachel, J., Stan, I., Stefanek, G., Stefanini, G., Steinbeck, T., Steinpreis, M., Stenlund, E., Steyn, G., Stocco, D., Stock, R., Stokkevag, C.H., Stolpovskiy, M., Strmen, P., Suaide, A.A.P., Subieta Vásquez, M.A., Sugitate, T., Suire, C., Sukhorukov, M., Šumbera, M., Susa, T., Swoboda, D., Symons, T.J.M., Szanto de Toledo, A., Szarka, I., Szostak, A., Tagridis, C., Takahashi, J., Tapia Takaki, J.D., Tauro, A., Tejeda Muñoz, G., Telesca, A., Terrevoli, C., Thäder, J., Thomas, D., Thomas, J.H., Tieulent, R., Timmins, A.R., Tlusty, D., Toia, A., Torii, H., Tosello, F., Traczyk, T., Truesdale, D., Trzaska, W.H., Tumkin, A., Turrisi, R., Turvey, A.J., Tveter, T.S., Ulery, J., Ullaland, K., Uras, A., Urbán, J., Urciuoli, G.M., Usai, G.L., Vajzer, M., Vala, M., Valencia Palomo, L., Vallero, S., van der Kolk, N., van Leeuwen, M., Vande Vyvre, P., Vannucci, L., Vargas, A., Varma, R., Vasileiou, M., Vasiliev, A., Vechernin, V., Veldhoen, M., Venaruzzo, M., Vercellin, E., Vergara, S., Vernekohl, D.C., Vernet, R., Verweij, M., Vickovic, L., Viesti, G., Vikhlyantsev, O., Vilakazi, Z., Villalobos Baillie, O., Vinogradov, A., Vinogradov, L., Vinogradov, Y., Virgili, T., Viyogi, Y.P., Vodopyanov, A., Voloshin, K., Voloshin, S., Volpe, G., von Haller, B., Vranic, D., Vrláková, J., Vulpescu, B., Vyushin, A., Wagner, B., Wagner, V., Wan, R., Wang, D., Wang, M., Wang, Y., Watanabe, K., Wessels, J.P., Westerhoff, U., Wiechula, J., Wikne, J., Wilde, M., Wilk, A., Wilk, G., Williams, M.C.S., Windelband, B., Yang, H., Yasnopolskiy, S., Yi, J., Yin, Z., Yokoyama, H., Yoo, I.-K., Yuan, X., Yushmanov, I., Zabrodin, E., Zach, C., Zampolli, C., Zaporozhets, S., Zarochentsev, A., Závada, P., Zaviyalov, N., Zbroszczyk, H., Zelnicek, P., Zenin, A., Zgura, I., Zhalov, M., Zhang, X., Zhou, D., Zhou, F., Zhou, Y., Zhu, X., Zichichi, A., Zinovjev, G., Zoccarato, Y., and Zynovyev, M.
Subjects: Proton-Proton Collisions, Alice, LHC
Abstract: The ALICE experiment at the LHC has studied inclusive J/ψ production at central and forward rapidities in pp collisions at s=7 TeV. In this Letter, we report on the first results obtained detecting the J/ψ through the dilepton decay into e+e− and μ+μ− pairs in the rapidity ranges |y
Published: 2011

47. Two-pion Bose-Einstein correlations in central Pb-Pb collisions at √s NN =2.76 TeV

Author: Aamodt, K. Abrahantes Quintana, A. Adamová, D. Adare, A.M. Aggarwal, M.M. Aglieri Rinella, G. Agocs, A.G. Aguilar Salazar, S. Ahammed, Z. Ahmad, N. Ahmad Masoodi, A. Ahn, S.U. Akindinov, A. Aleksandrov, D. Alessandro, B. Alfaro Molina, R. Alici, A. Alkin, A. Almaráz Aviña, E. Alt, T. Altini, V. Altinpinar, S. Altsybeev, I. Andrei, C. Andronic, A. Anguelov, V. Anson, C. Antičić, T. Antinori, F. Antonioli, P. Aphecetche, L. Appelshäuser, H. Arbor, N. Arcelli, S. Arend, A. Armesto, N. Arnaldi, R. Aronsson, T. Arsene, I.C. Asryan, A. Augustinus, A. Averbeck, R. Awes, T.C. Äystö, J. Azmi, M.D. Bach, M. Badalà, A. Baek, Y.W. Bagnasco, S. Bailhache, R. Bala, R. Baldini Ferroli, R. Baldisseri, A. Baldit, A. Bán, J. Barbera, R. Barile, F. Barnaföldi, G.G. Barnby, L.S. Barret, V. Bartke, J. Basile, M. Bastid, N. Bathen, B. Batigne, G. Batyunya, B. Baumann, C. Bearden, I.G. Beck, H. Belikov, I. Bellini, F. Bellwied, R. Belmont-Moreno, E. Beole, S. Berceanu, I. Bercuci, A. Berdermann, E. Berdnikov, Y. Betev, L. Bhasin, A. Bhati, A.K. Bianchi, L. Bianchi, N. Bianchin, C. Bielčík, J. Bielčík, ová, J. Bilandzic, A. Biolcati, E. Blanc, A. Blanco, F. Blanco, F. Blau, D. Blume, C. Boccioli, M. Bock, N. Bogdanov, A. Bøggild, H. Bogolyubsky, M. Boldizsár, L. Bombara, M. Bombonati, C. Book, J. Borel, H. Bortolin, C. Bose, S. Bossú, F. Botje, M. Böttger, S. Boyer, B. Braun-Munzinger, P. Bravina, L. Bregant, M. Breitner, T. Broz, M. Brun, R. Bruna, E. Bruno, G.E. Budnikov, D. Buesching, H. Busch, O. Buthelezi, Z. Caffarri, D. Cai, X. Caines, H. Calvo Villar, E. Camerini, P. Canoa Roman, V. Cara Romeo, G. Carena, F. Carena, W. Carminati, F. Casanova Díaz, A. Caselle, M. Castillo Castellanos, J. Catanescu, V. Cavicchioli, C. Cerello, P. Chang, B. Chapeland, S. Charvet, J.L. Chattopadhyay, S. Chattopadhyay, S. Cherney, M. Cheshkov, C. Cheynis, B. Chiavassa, E. Chibante Barroso, V. Chinellato, D.D. Chochula, P. Chojnacki, M. Christakoglou, P. Christensen, C.H. Christiansen, P. Chujo, T. Cicalo, C. Cifarelli, L. Cindolo, F. Cleymans, J. Coccetti, F. Coffin, J.-P. Coli, S. Conesa Balbastre, G. Conesa del Valle, Z. Constantin, P. Contin, G. Contreras, J.G. Cormier, T.M. Corrales Morales, Y. Cortés Maldonado, I. Cortese, P. Cosentino, M.R. Costa, F. Cotallo, M.E. Crescio, E. Crochet, P. Cuautle, E. Cunqueiro, L. D'Erasmo, G. Dainese, A. Dalsgaard, H.H. Danu, A. Das, D. Das, I. Dash, A. Dash, S. De, S. De Azevedo Moregula, A. de Barros, G.O.V. De Caro, A. de Cataldo, G. de Cuveland, J. De Falco, A. De Gruttola, D. De Marco, N. De Pasquale, S. De Remigis, R. de Rooij, R. Delagrange, H. Delgado Mercado, Y. Dellacasa, G. Deloff, A. Demanov, V. Dénes, E. Deppman, A. Di Bari, D. Di Giglio, C. Di Liberto, S. Di Mauro, A. Di Nezza, P. Dietel, T. Divià, R. Djuvsland, O. Dobrin, A. Dobrowolski, T. Domínguez, I. Dönigus, B. Dordic, O. Driga, O. Dubey, A.K. Ducroux, L. Dupieux, P. Dutta Majumdar, A.K. Dutta Majumdar, M.R. Elia, D. Emschermann, D. Engel, H. Erdal, H.A. Espagnon, B. Estienne, M. Esumi, S. Evans, D. Evrard, S. Eyyubova, G. Fabjan, C.W. Fabris, D. Faivre, J. Falchieri, D. Fantoni, A. Fasel, M. Fearick, R. Fedunov, A. Fehlker, D. Fekete, V. Felea, D. Feofilov, G. Fernández Téllez, A. Ferretti, A. Ferretti, R. Figueredo, M.A.S. Filchagin, S. Fini, R. Finogeev, D. Fionda, F.M. Fiore, E.M. Floris, M. Foertsch, S. Foka, P. Fokin, S. Fragiacomo, E. Fragkiadakis, M. Frankenfeld, U. Fuchs, U. Furano, F. Furget, C. Fusco Girard, M. Gaardhøje, J.J. Gadrat, S. Gagliardi, M. Gago, A. Gallio, M. Ganoti, P. Garabatos, C. Gemme, R. Gerhard, J. Germain, M. Geuna, C. Gheata, A. Gheata, M. Ghidini, B. Ghosh, P. Girard, M.R. Giraudo, G. Giubellino, P. Gladysz-Dziadus, E. Glässel, P. Gomez, R. González-Trueba, L.H. González-Zamora, P. González Santos, H. Gorbunov, S. Gotovac, S. Grabski, V. Grajcarek, R. Gramling, J.L. Grelli, A. Grigoras, A. Grigoras, C. Grigoriev, V. Grigoryan, A. Grigoryan, S. Grinyov, B. Grion, N. Gros, P. Grosse-Oetringhaus, J.F. Grossiord, J.-Y. Grosso, R. Guber, F. Guernane, R. Guerra Gutierrez, C. Guerzoni, B. Gulbrandsen, K. Gulkanyan, H. Gunji, T. Gupta, A. Gupta, R. Gutbrod, H. Haaland, O. Hadjidakis, C. Haiduc, M. Hamagaki, H. Hamar, G. Harris, J.W. Hartig, M. Hasch, D. Hasegan, D. Hatzifotiadou, D. Hayrapetyan, A. Heide, M. Heinz, M. Helstrup, H. Herghelegiu, A. Hernández, C. Herrera Corral, G. Herrmann, N. Hetland, K.F. Hicks, B. Hille, P.T. Hippolyte, B. Horaguchi, T. Hori, Y. Hristov, P. Hřivnáčová, I. Huang, M. Huber, S. Humanic, T.J. Hwang, D.S. Ichou, R. Ilkaev, R. Ilkiv, I. Inaba, M. Incani, E. Innocenti, G.M. Innocenti, P.G. Ippolitov, M. Irfan, M. Ivan, C. Ivanov, A. Ivanov, M. Ivanov, V. Jacholkowski, A. Jacobs, P.M. Jancurová, L. Jangal, S. Janik, R. Jayarathna, S.P. Jena, S. Jirden, L. Jones, G.T. Jones, P.G. Jovanović, P. Jung, H. Jung, W. Jusko, A. Kalcher, S. Kaliňák, P. Kalisky, M. Kalliokoski, T. Kalweit, A. Kamermans, R. Kanaki, K. Kang, E. Kang, J.H. Kaplin, V. Karavichev, O. Karavicheva, T. Karpechev, E. Kazantsev, A. Kebschull, U. Keidel, R. Khan, M.M. Khanzadeev, A. Kharlov, Y. Kileng, B. Kim, D.J. Kim, D.S. Kim, D.W. Kim, H.N. Kim, J.H. Kim, J.S. Kim, M. Kim, M. Kim, S. Kim, S.H. Kirsch, S. Kisel, I. Kiselev, S. Kisiel, A. Klay, J.L. Klein, J. Klein-Bösing, C. Kliemant, M. Klovning, A. Kluge, A. Knichel, M.L. Koch, K. Köhler, M.K. Kolevatov, R. Kolojvari, A. Kondratiev, V. Kondratyeva, N. Konevskih, A. Kornaś, E. Kottachchi Kankanamge Don, C. Kour, R. Kowalski, M. Kox, S. Koyithatta Meethaleveedu, G. Kozlov, K. Kral, J. Králik, I. Kramer, F. Kraus, I. Krawutschke, T. Kretz, M. Krivda, M. Krumbhorn, D. Krus, M. Kryshen, E. Krzewicki, M. Kucheriaev, Y. Kuhn, C. Kuijer, P.G. Kurashvili, P. Kurepin, A. Kurepin, A.B. Kuryakin, A. Kushpil, S. Kushpil, V. Kweon, M.J. Kwon, Y. La Rocca, P. Ladrón de Guevara, P. Lafage, V. Lara, C. Larsen, D.T. Lazzeroni, C. Le Bornec, Y. Lea, R. Lee, K.S. Lee, S.C. Lefèvre, F. Lehnert, J. Leistam, L. Lenhardt, M. Lenti, V. León Monzón, I. León Vargas, H. Lévai, P. Li, X. Lietava, R. Lindal, S. Lindenstruth, V. Lippmann, C. Lisa, M.A. Liu, L. Loggins, V.R. Loginov, V. Lohn, S. Lohner, D. Loizides, C. Lopez, X. López Noriega, M. López Torres, E. Løvhøiden, G. Lu, X.-G. Luettig, P. Lunardon, M. Luparello, G. Luquin, L. Luzzi, C. Ma, K. Ma, R. Madagodahettige-Don, D.M. Maevskaya, A. Mager, M. Mahapatra, D.P. Maire, A. Malaev, M. Maldonado Cervantes, I. Malinina, L. Mal'Kevich, D. Malzacher, P. Mamonov, A. Manceau, L. Mangotra, L. Manko, V. Manso, F. Manzari, V. Mao, Y. Mareš, J. Margagliotti, G.V. Margotti, A. Marín, A. Martashvili, I. Martinengo, P. Martínez, M.I. Martínez Davalos, A. Martínez García, G. Martynov, Y. Mas, A. Masciocchi, S. Masera, M. Masoni, A. Massacrier, L. Mastromarco, M. Mastroserio, A. Matthews, Z.L. Matyja, A. Mayani, D. Mazza, G. Mazzoni, M.A. Meddi, F. Menchaca-Rocha, A. Mendez Lorenzo, P. Mercado Pérez, J. Mereu, P. Miake, Y. Midori, J. Milano, L. Milosevic, J. Mischke, A. Miśkowiec, D. Mitu, C. Mlynarz, J. Mohanty, B. Molnar, L. Montaño Zetina, L. Monteno, M. Montes, E. Morando, M. Moreira De Godoy, D.A. Moretto, S. Morsch, A. Muccifora, V. Mudnic, E. Müller, H. Muhuri, S. Munhoz, M.G. Munoz, J. Musa, L. Musso, A. Nandi, B.K. Nania, R. Nappi, E. Nattrass, C. Navach, F. Navin, S. Nayak, T.K. Nazarenko, S. Nazarov, G. Nedosekin, A. Nendaz, F. Newby, J. Nicassio, M. Nielsen, B.S. Nikolaev, S. Nikolic, V. Nikulin, S. Nikulin, V. Nilsen, B.S. Nilsson, M.S. Noferini, F. Nooren, G. Novitzky, N. Nyanin, A. Nyatha, A. Nygaard, C. Nystrand, J. Obayashi, H. Ochirov, A. Oeschler, H. Oh, S.K. Oleniacz, J. Oppedisano, C. Ortiz Velasquez, A. Ortona, G. Oskarsson, A. Ostrowski, P. Otterlund, I. Otwinowski, J. Ø, G. Oyama, K. Ozawa, K. Pachmayer, Y. Pachr, M. Padilla, F. Pagano, P. Paiá, G. Painke, F. Pajares, C. Pal, S. Pal, S.K. Palaha, A. Palmeri, A. Pappalardo, G.S. Park, W.J. Paticchio, V. Pavlinov, A. Pawlak, T. Peitzmann, T. Peresunko, D. Pérez Lara, C.E. Perini, D. Perrino, D. Peryt, W. Pesci, A. Peskov, V. Pestov, Y. Peters, A.J. Petráček, V. Petris, M. Petrov, P. Petrovici, M. Petta, C. Piano, S. Piccotti, A. Pikna, M. Pillot, P. Pinazza, O. Pinsky, L. Pitz, N. Piuz, F. Piyarathna, D.B. Platt, R. Pylstoke, and oskoń, M. Pluta, J. Pocheptsov, T. Pochybova, S. Podesta-Lerma, P.L.M. Poghosyan, M.G. Polák, K. Polichtchouk, B. Pop, A. Pospíšil, V. Potukuchi, B. Prasad, S.K. Preghenella, R. Prino, F. Pruneau, C.A. Pshenichnov, I. Puddu, G. Pulvirenti, A. Punin, V. Putiš, M. Putschke, J. Quercigh, E. Qvigstad, H. Rachevski, A. Rademakers, A. Rademakers, O. Radomski, S. Räihä, T.S. Rak, J. Rakotozafindrabe, A. Ramello, L. Ramírez Reyes, A. Rammler, M. Raniwala, R. Raniwala, S. Räsänen, S.S. Read, K.F. Real, J.S. Redlich, K. Renfordt, R. Reolon, A.R. Reshetin, A. Rettig, F. Revol, J.-P. Reygers, K. Ricaud, H. Riccati, L. Ricci, R.A. Richter, M. Riedler, P. Riegler, W. Riggi, F. Rivetti, A. Rodríguez Cahuantzi, M. Rohr, D. Röhrich, D. Romita, R. Ronchetti, F. Rosinskỳ, P. Rosnet, P. Rossegger, S. Rossi, A. Roukoutakis, F. Rousseau, S. Roy, C. Roy, P. Rubio Montero, A.J. Rui, R. Rusanov, I. Ryabinkin, E. Rybicki, A. Sadovsky, S. Šafařík, K. Sahoo, R. Sahu, P.K. Saiz, P. Sakai, S. Sakata, D. Salgado, C.A. Samanta, T. Sambyal, S. Samsonov, V. Šándor, L. Sandoval, A. Sano, M. Sano, S. Santo, R. Santoro, R. Sarkamo, J. Saturnini, P. Scapparone, E. Scarlassara, F. Scharenberg, R.P. Schiaua, C. Schicker, R. Schmidt, C. Schmidt, H.R. Schreiner, S. Schuchmann, S. Schukraft, J. Schutz, Y. Schwarz, K. Schweda, K. Scioli, G. Scomparin, E. Scott, P.A. Scott, R. Segato, G. Senyukov, S. Seo, J. Serci, S. Serradilla, E. Sevcenco, A. Shabratova, G. Shahoyan, R. Sharma, N. Sharma, S. Shigaki, K. Shimomura, M. Shtejer, K. Sibiriak, Y. Siciliano, M. Sicking, E. Siemiarczuk, T. Silenzi, A. Silvermyr, D. Simonetti, G. Singaraju, R. Singh, R. Sinha, B.C. Sinha, T. Sitar, B. Sitta, M. Skaali, T.B. Skjerdal, K. Smakal, R. Smirnov, N. Snellings, R. Søgaard, C. Soloviev, A. Soltz, R. Son, H. Song, M. Soos, C. Soramel, F. Spyropoulou-Stassinaki, M. Srivastava, B.K. Stachel, J. Stan, I. Stefanek, G. Stefanini, G. Steinbeck, T. Stenlund, E. Steyn, G. Stocco, D. Stock, R. Stolpovskiy, M. Strmen, P. Suaide, A.A.P. Subieta Vásquez, M.A. Sugitate, T. Suire, C. Šumbera, M. Susa, T. Swoboda, D. Symons, T.J.M. Szanto de Toledo, A. Szarka, I. Szostak, A. Tagridis, C. Takahashi, J. Tapia Takaki, J.D. Tauro, A. Tavlet, M. Tejeda Muñoz, G. Telesca, A. Terrevoli, C. Thäder, J. Thomas, D. Thomas, J.H. Tieulent, R. Timmins, A.R. Tlusty, D. Toia, A. Torii, H. Toscano, L. Tosello, F. Traczyk, T. Truesdale, D. Trzaska, W.H. Tumkin, A. Turrisi, R. Turvey, A.J. Tveter, T.S. Ulery, J. Ullaland, K. Uras, A. Urbán, J. Urciuoli, G.M. Usai, G.L. Vacchi, A. Vala, M. Valencia Palomo, L. Vallero, S. van der Kolk, N. van Leeuwen, M. Vande Vyvre, P. Vannucci, L. Vargas, A. Varma, R. Vasileiou, M. Vasiliev, A. Vechernin, V. Venaruzzo, M. Vercellin, E. Vergara, S. Vernet, R. Verweij, M. Vickovic, L. Viesti, G. Vikhlyantsev, O. Vilakazi, Z. Villalobos Baillie, O. Vinogradov, A. Vinogradov, L. Vinogradov, Y. Virgili, T. Viyogi, Y.P. Vodopyanov, A. Voloshin, K. Voloshin, S. Volpe, G. von Haller, B. Vranic, D. Vrláková, J. Vulpescu, B. Wagner, B. Wagner, V. Wan, R. Wang, D. Wang, Y. Wang, Y. Watanabe, K. Wessels, J.P. Westerhoff, U. Wiechula, J. Wikne, J. Wilde, M. Wilk, A. Wilk, G. Williams, M.C.S. Windelband, B. Yang, H. Yasnopolskiy, S. Yi, J. Yin, Z. Yokoyama, H. Yoo, I.-K. Yuan, X. Yushmanov, I. Zabrodin, E. Zampolli, C. Zaporozhets, S. Zarochentsev, A. Závada, P. Zbroszczyk, H. Zelnicek, P. Zenin, A. Zgura, I. Zhalov, M. Zhang, X. Zhou, D. Zhu, X. Zichichi, A. Zinovjev, G. Zoccarato, Y. Zynovyev, M.
Subjects: Nuclear Theory, Physics::Accelerator Physics, High Energy Physics::Experiment, Nuclear Experiment
Abstract: The first measurement of two-pion Bose-Einstein correlations in central Pb-Pb collisions at √s NN =2.76 TeV at the Large Hadron Collider is presented. We observe a growing trend with energy now not only for the longitudinal and the outward but also for the sideward pion source radius. The pion homogeneity volume and the decoupling time are significantly larger than those measured at RHIC. © 2010 CERN.
Published: 2011

48. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

Author: Schunkert, H. König, I.R. Kathiresan, S. Reilly, M.P. Assimes, T.L. Holm, H. Preuss, M. Stewart, A.F.R. Barbalic, M. Gieger, C. Absher, D. Aherrahrou, Z. Allayee, H. Altshuler, D. Anand, S.S. Andersen, K. Anderson, J.L. Ardissino, D. Ball, S.G. Balmforth, A.J. Barnes, T.A. Becker, D.M. Becker, L.C. Berger, K. Bis, J.C. Boekholdt, S.M. Boerwinkle, E. Braund, P.S. Brown, M.J. Burnett, M.S. Buysschaert, I. Carlquist, J.F. Chen, L. Cichon, S. Codd, V. Davies, R.W. Dedoussis, G. Dehghan, A. Demissie, S. Devaney, J.M. Diemert, P. Do, R. Doering, A. Eifert, S. Mokhtari, N.E.E. Ellis, S.G. Elosua, R. Engert, J.C. Epstein, S.E. De Faire, U. Fischer, M. Folsom, A.R. Freyer, J. Gigante, B. Girelli, D. Gretarsdottir, S. Gudnason, V. Gulcher, J.R. Halperin, E. Hammond, N. Hazen, S.L. Hofman, A. Horne, B.D. Illig, T. Iribarren, C. Jones, G.T. Jukema, J.W. Kaiser, M.A. Kaplan, L.M. Kastelein, J.J.P. Khaw, K.-T. Knowles, J.W. Kolovou, G. Kong, A. Laaksonen, R. Lambrechts, D. Leander, K. Lettre, G. Li, M. Lieb, W. Loley, C. Lotery, A.J. Mannucci, P.M. Maouche, S. Martinelli, N. McKeown, P.P. Meisinger, C. Meitinger, T. Melander, O. Merlini, P.A. Mooser, V. Morgan, T. Mühleisen, T.W. Muhlestein, J.B. Münzel, T. Musunuru, K. Nahrstaedt, J. Nelson, C.P. Nöthen, M.M. Olivieri, O. Patel, R.S. Patterson, C.C. Peters, A. Peyvandi, F. Qu, L. Quyyumi, A.A. Rader, D.J. Rallidis, L.S. Rice, C. Rosendaal, F.R. Rubin, D. Salomaa, V. Sampietro, M.L. Sandhu, M.S. Schadt, E. Scḧsignfer, A. Schillert, A. Schreiber, S. Schrezenmeir, J. Schwartz, S.M. Siscovick, D.S. Sivananthan, M. Sivapalaratnam, S. Smith, A. Smith, T.B. Snoep, J.D. Soranzo, N. Spertus, J.A. Stark, K. Stirrups, K. Stoll, M. Tang, W.H.W. Tennstedt, S. Thorgeirsson, G. Thorleifsson, G. Tomaszewski, M. Uitterlinden, A.G. Van Rij, A.M. Voight, B.F. Wareham, N.J. Wells, G.A. Wichmann, H.-E. Wild, P.S. Willenborg, C. Witteman, J.C.M. Wright, B.J. Ye, S. Zeller, T. Ziegler, A. Cambien, F. Goodall, A.H. Cupples, L.A. Quertermous, T. Mäsignrz, W. Hengstenberg, C. Blankenberg, S. Ouwehand, W.H. Hall, A.S. Deloukas, P. Thompson, J.R. Stefansson, K. Roberts, R. Thorsteinsdottir, U. O'Donnell, C.J. McPherson, R. Erdmann, J. Samani, N.J.
Subjects: cardiovascular diseases
Abstract: We performed a meta-analysis of 14 genome-wide association studies of coronary artery disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of European descent followed by genotyping of top association signals in 56,682 additional individuals. This analysis identified 13 loci newly associated with CAD at P < 5 - 10'8 and confirmed the association of 10 of 12 previously reported CAD loci. The 13 new loci showed risk allele frequencies ranging from 0.13 to 0.91 and were associated with a 6% to 17% increase in the risk of CAD per allele. Notably, only three of the new loci showed significant association with traditional CAD risk factors and the majority lie in gene regions not previously implicated in the pathogenesis of CAD. Finally, five of the new CAD risk loci appear to have pleiotropic effects, showing strong association with various other human diseases or traits. © 2011 Nature America, Inc. All rights reserved.
Published: 2011

49. Strange particle production in proton–proton collisions at √s = 0.9 TeV with ALICE at the LHC

Author: Aamodt, K. Abrahantes Quintana, A. Adamová, D. Adare, A.M. Aggarwal, M.M. Aglieri Rinella, G. Agocs, A.G. Aguilar Salazar, S. Ahammed, Z. Ahmad, N. Ahmad Masoodi, A. Ahn, S.U. Akindinov, A. Aleksandrov, D. Alessandro, B. Alfaro Molina, R. Alici, A. Alkin, A. Almaráz Aviña, E. Alt, T. Altini, V. Altinpinar, S. Altsybeev, I. Andrei, C. Andronic, A. Anguelov, V. Anson, C. Antičić, T. Antinori, F. Antonioli, P. Aphecetche, L. Appelshäuser, H. Arbor, N. Arcelli, S. Arend, A. Armesto, N. Arnaldi, R. Aronsson, T. Arsene, I.C. Asryan, A. Augustinus, A. Averbeck, R. Awes, T.C. Äystö, J. Azmi, M.D. Bach, M. Badalà, A. Baek, Y.W. Bagnasco, S. Bailhache, R. Bala, R. Baldini Ferroli, R. Baldisseri, A. Baldit, A. Bán, J. Barbera, R. Barile, F. Barnaföldi, G.G. Barnby, L.S. Barret, V. Bartke, J. Basile, M. Bastid, N. Bathen, B. Batigne, G. Batyunya, B. Baumann, C. Bearden, I.G. Beck, H. Belikov, I. Bellini, F. Bellwied, R. Belmont-Moreno, E. Beole, S. Berceanu, I. Bercuci, A. Berdermann, E. Berdnikov, Y. Betev, L. Bhasin, A. Bhati, A.K. Bianchi, L. Bianchi, N. Bianchin, C. Bielčík, J. Bielčíková, J. Bilandzic, A. Biolcati, E. Blanc, A. Blanco, F. Blanco, F. Blau, D. Blume, C. Boccioli, M. Bock, N. Bogdanov, A. Bøggild, H. Bogolyubsky, M. Boldizsár, L. Bombara, M. Bombonati, C. Book, J. Borel, H. Bortolin, C. Bose, S. Bossú, F. Botje, M. Böttger, S. Boyer, B. Braun-Munzinger, P. Bravina, L. Bregant, M. Breitner, T. Broz, M. Brun, R. Bruna, E. Bruno, G.E. Budnikov, D. Buesching, H. Busch, O. Buthelezi, Z. Caffarri, D. Cai, X. Caines, H. Calvo Villar, E. Camerini, P. Canoa Roman, V. Cara Romeo, G. Carena, F. Carena, W. Carminati, F. Casanova Díaz, A. Caselle, M. Castillo Castellanos, J. Catanescu, V. Cavicchioli, C. Cerello, P. Chang, B. Chapeland, S. Charvet, J.L. Chattopadhyay, S. Chattopadhyay, S. Cherney, M. Cheshkov, C. Cheynis, B. Chiavassa, E. Chibante Barroso, V. Chinellato, D.D. Chochula, P. Chojnacki, M. Christakoglou, P. Christensen, C.H. Christiansen, P. Chujo, T. Cicalo, C. Cifarelli, L. Cindolo, F. Cleymans, J. Coccetti, F. Coffin, J.-P. Coli, S. Conesa Balbastre, G. Conesa del Valle, Z. Constantin, P. Contin, G. Contreras, J.G. Cormier, T.M. Corrales Morales, Y. Cortés Maldonado, I. Cortese, P. Cosentino, M.R. Costa, F. Cotallo, M.E. Crescio, E. Crochet, P. Cuautle, E. Cunqueiro, L. Erasmo, G.D. Dainese, A. Dalsgaard, H.H. Danu, A. Das, D. Das, I. Dash, A. Dash, S. De, S. De Azevedo Moregula, A. de Barros, G.O.V. De Caro, A. de Cataldo, G. de Cuveland, J. De Falco, A. De Gruttola, D. De Marco, N. De Pasquale, S. De Remigis, R. de Rooij, R. Delagrange, H. Delgado Mercado, Y. Dellacasa, G. Deloff, A. Demanov, V. Dénes, E. Deppman, A. Di Bari, D. Di Giglio, C. Di Liberto, S. Di Mauro, A. Di Nezza, P. Dietel, T. Divià, R. Djuvsland, Ø. Dobrin, A. Dobrowolski, T. Domínguez, I. Dönigus, B. Dordic, O. Driga, O. Dubey, A.K. Dubuisson, J. Ducroux, L. Dupieux, P. Dutta Majumdar, A.K. Dutta Majumdar, M.R. Elia, D. Emschermann, D. Engel, H. Erdal, H.A. Espagnon, B. Estienne, M. Esumi, S. Evans, D. Evrard, S. Eyyubova, G. Fabjan, C.W. Fabris, D. Faivre, J. Falchieri, D. Fantoni, A. Fasel, M. Fearick, R. Fedunov, A. Fehlker, D. Fekete, V. Felea, D. Feofilov, G. Fernández Téllez, A. Ferretti, A. Ferretti, R. Figueredo, M.A.S. Filchagin, S. Fini, R. Finogeev, D. Fionda, F.M. Fiore, E.M. Floris, M. Foertsch, S. Foka, P. Fokin, S. Fragiacomo, E. Fragkiadakis, M. Frankenfeld, U. Fuchs, U. Furano, F. Furget, C. Fusco Girard, M. Gaardhøje, J.J. Gadrat, S. Gagliardi, M. Gago, A. Gallio, M. Ganoti, P. Garabatos, C. Gemme, R. Gerhard, J. Germain, M. Geuna, C. Gheata, A. Gheata, M. Ghidini, B. Ghosh, P. Girard, M.R. Giraudo, G. Giubellino, P. Gladysz-Dziadus, E. Glässel, P. Gomez, R. González-Trueba, L.H. González-Zamora, P. González Santos, H. Gorbunov, S. Gotovac, S. Grabski, V. Grajcarek, R. Grelli, A. Grigoras, A. Grigoras, C. Grigoriev, V. Grigoryan, A. Grigoryan, S. Grinyov, B. Grion, N. Gros, P. Grosse-Oetringhaus, J.F. Grossiord, J.-Y. Grosso, R. Guber, F. Guernane, R. Guerra Gutierrez, C. Guerzoni, B. Gulbrandsen, K. Gunji, T. Gupta, A. Gupta, R. Gutbrod, H. Haaland, Ø. Hadjidakis, C. Haiduc, M. Hamagaki, H. Hamar, G. Harris, J.W. Hartig, M. Hasch, D. Hasegan, D. Hatzifotiadou, D. Hayrapetyan, A. Heide, M. Heinz, M. Helstrup, H. Herghelegiu, A. Hernández, C. Herrera Corral, G. Herrmann, N. Hetland, K.F. Hicks, B. Hille, P.T. Hippolyte, B. Horaguchi, T. Hori, Y. Hristov, P. Hřivnáčová, I. Huang, M. Huber, S. Humanic, T.J. Hwang, D.S. Ichou, R. Ilkaev, R. Ilkiv, I. Inaba, M. Incani, E. Innocenti, G.M. Innocenti, P.G. Ippolitov, M. Irfan, M. Ivan, C. Ivanov, A. Ivanov, M. Ivanov, V. Jacholkowski, A. Jacobs, P.M. Jancurová, L. Jangal, S. Janik, R. Jayarathna, S.P. Jena, S. Jirden, L. Jones, G.T. Jones, P.G. Jovanović, P. Jung, H. Jung, W. Jusko, A. Kalcher, S. Kaliňák, P. Kalisky, M. Kalliokoski, T. Kalweit, A. Kamermans, R. Kanaki, K. Kang, E. Kang, J.H. Kaplin, V. Karavichev, O. Karavicheva, T. Karpechev, E. Kazantsev, A. Kebschull, U. Keidel, R. Khan, M.M. Khanzadeev, A. Kharlov, Y. Kileng, B. Kim, D.J. Kim, D.S. Kim, D.W. Kim, H.N. Kim, J.H. Kim, J.S. Kim, M. Kim, M. Kim, S. Kim, S.H. Kirsch, S. Kisel, I. Kiselev, S. Kisiel, A. Klay, J.L. Klein, J. Klein-Bösing, C. Kliemant, M. Klovning, A. Kluge, A. Knichel, M.L. Koch, K. Köhler, M.K. Kolevatov, R. Kolojvari, A. Kondratiev, V. Kondratyeva, N. Konevskih, A. Kornaś, E. Kottachchi Kankanamge Don, C. Kour, R. Kowalski, M. Kox, S. Kozlov, K. Kral, J. Králik, I. Kramer, F. Kraus, I. Krawutschke, T. Kretz, M. Krivda, M. Krumbhorn, D. Krus, M. Kryshen, E. Krzewicki, M. Kucheriaev, Y. Kuhn, C. Kuijer, P.G. Kurashvili, P. Kurepin, A. Kurepin, A.B. Kuryakin, A. Kushpil, S. Kushpil, V. Kweon, M.J. Kwon, Y. La Rocca, P. Ladrón de Guevara, P. Lafage, V. Lara, C. Larsen, D.T. Lazzeroni, C. Le Bornec, Y. Lea, R. Lee, K.S. Lee, S.C. Lefèvre, F. Lehnert, J. Leistam, L. Lenhardt, M. Lenti, V. León Monzón, I. León Vargas, H. Lévai, P. Li, X. Lietava, R. Lindal, S. Lindenstruth, V. Lippmann, C. Lisa, M.A. Liu, L. Loggins, V.R. Loginov, V. Lohn, S. Lohner, D. Lopez, X. López Noriega, M. López Torres, E. Løvhøiden, G. Lu, X.-G. Luettig, P. Lunardon, M. Luparello, G. Luquin, L. Luzzi, C. Ma, K. Ma, R. Madagodahettige-Don, D.M. Maevskaya, A. Mager, M. Mahapatra, D.P. Maire, A. Malaev, M. Maldonado Cervantes, I. Mal'Kevich, D. Malzacher, P. Mamonov, A. Manceau, L. Mangotra, L. Manko, V. Manso, F. Manzari, V. Mao, Y. Mareš, J. Margagliotti, G.V. Margotti, A. Marín, A. Martashvili, I. Martinengo, P. Martínez, M.I. Martínez Davalos, A. Martínez García, G. Martynov, Y. Mas, A. Masciocchi, S. Masera, M. Masoni, A. Massacrier, L. Mastromarco, M. Mastroserio, A. Matthews, Z.L. Matyja, A. Mayani, D. Mazza, G. Mazzoni, M.A. Meddi, F. Menchaca-Rocha, A. Mendez Lorenzo, P. Mercado Pérez, J. Mereu, P. Miake, Y. Midori, J. Milano, L. Milosevic, J. Mischke, A. Miśkowiec, D. Mitu, C. Mlynarz, J. Mohanty, B. Molnar, L. Montaño Zetina, L. Monteno, M. Montes, E. Morando, M. Moreira De Godoy, D.A. Moretto, S. Morsch, A. Muccifora, V. Mudnic, E. Müller, H. Muhuri, S. Munhoz, M.G. Munoz, J. Musa, L. Musso, A. Nandi, B.K. Nania, R. Nappi, E. Nattrass, C. Navach, F. Navin, S. Nayak, T.K. Nazarenko, S. Nazarov, G. Nedosekin, A. Nendaz, F. Newby, J. Nicassio, M. Nielsen, B.S. Nikolaev, S. Nikolic, V. Nikulin, S. Nikulin, V. Nilsen, B.S. Nilsson, M.S. Noferini, F. Nooren, G. Novitzky, N. Nyanin, A. Nyatha, A. Nygaard, C. Nystrand, J. Obayashi, H. Ochirov, A. Oeschler, H. Oh, S.K. Oleniacz, J. Oppedisano, C. Ortiz Velasquez, A. Ortona, G. Oskarsson, A. Ostrowski, P. Otterlund, I. Otwinowski, J. Øvrebekk, G. Oyama, K. Ozawa, K. Pachmayer, Y. Pachr, M. Padilla, F. Pagano, P. Paić, G. Painke, F. Pajares, C. Pal, S. Pal, S.K. Palaha, A. Palmeri, A. Pappalardo, G.S. Park, W.J. Paticchio, V. Pavlinov, A. Pawlak, T. Peitzmann, T. Peresunko, D. Pérez Lara, C.E. Perini, D. Perrino, D. Peryt, W. Pesci, A. Peskov, V. Pestov, Y. Peters, A.J. Petráček, V. Petris, M. Petrov, P. Petrovici, M. Petta, C. Piano, S. Piccotti, A. Pikna, M. Pillot, P. Pinazza, O. Pinsky, L. Pitz, N. Piuz, F. Piyarathna, D.B. Platt, R. Płoskoń, M. Pluta, J. Pocheptsov, T. Pochybova, S. Podesta-Lerma, P.L.M. Poghosyan, M.G. Polák, K. Polichtchouk, B. Pop, A. Pospíšil, V. Potukuchi, B. Prasad, S.K. Preghenella, R. Prino, F. Pruneau, C.A. Pshenichnov, I. Puddu, G. Pulvirenti, A. Punin, V. Putiš, M. Putschke, J. Quercigh, E. Qvigstad, H. Rachevski, A. Rademakers, A. Rademakers, O. Radomski, S. Räihä, T.S. Rak, J. Rakotozafindrabe, A. Ramello, L. Ramírez Reyes, A. Rammler, M. Raniwala, R. Raniwala, S. Räsänen, S.S. Read, K.F. Real, J.S. Redlich, K. Renfordt, R. Reolon, A.R. Reshetin, A. Rettig, F. Revol, J.-P. Reygers, K. Ricaud, H. Riccati, L. Ricci, R.A. Richter, M. Riedler, P. Riegler, W. Riggi, F. Rivetti, A. Rodríguez Cahuantzi, M. Rohr, D. Röhrich, D. Romita, R. Ronchetti, F. Rosinský, P. Rosnet, P. Rossegger, S. Rossi, A. Roukoutakis, F. Rousseau, S. Roy, C. Roy, P. Rubio Montero, A.J. Rui, R. Rusanov, I. Ryabinkin, E. Rybicki, A. Sadovsky, S. Šafařík, K. Sahoo, R. Sahu, P.K. Saiz, P. Sakai, S. Sakata, D. Salgado, C.A. Samanta, T. Sambyal, S. Samsonov, V. Šándor, L. Sandoval, A. Sano, M. Sano, S. Santo, R. Santoro, R. Sarkamo, J. Saturnini, P. Scapparone, E. Scarlassara, F. Scharenberg, R.P. Schiaua, C. Schicker, R. Schmidt, C. Schmidt, H.R. Schreiner, S. Schuchmann, S. Schukraft, J. Schutz, Y. Schwarz, K. Schweda, K. Scioli, G. Scomparin, E. Scott, P.A. Scott, R. Segato, G. Senyukov, S. Seo, J. Serci, S. Serradilla, E. Sevcenco, A. Shabratova, G. Shahoyan, R. Sharma, N. Sharma, S. Shigaki, K. Shimomura, M. Shtejer, K. Sibiriak, Y. Siciliano, M. Sicking, E. Siemiarczuk, T. Silenzi, A. Silvermyr, D. Simonetti, G. Singaraju, R. Singh, R. Sinha, B.C. Sinha, T. Sitar, B. Sitta, M. Skaali, T.B. Skjerdal, K. Smakal, R. Smirnov, N. Snellings, R. Søgaard, C. Soloviev, A. Soltz, R. Son, H. Song, M. Soos, C. 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Vikhlyantsev, O. Vilakazi, Z. Villalobos Baillie, O. Vinogradov, A. Vinogradov, L. Vinogradov, Y. Virgili, T. Viyogi, Y.P. Vodopyanov, A. Voloshin, K. Voloshin, S. Volpe, G. vonHaller, B. Vranic, D. Vrláková, J. Vulpescu, B. Wagner, B. Wagner, V. Wan, R. Wang, D. Wang, Y. Wang, Y. Watanabe, K. Wessels, J.P. Westerhoff, U. Wiechula, J. Wikne, J. Wilde, M. Wilk, A. Wilk, G. Williams, M.C.S. Windelband, B. Yang, H. Yasnopolskiy, S. Yi, J. Yin, Z. Yokoyama, H. Yoo, I.-K. Yuan, X. Yushmanov, I. Zabrodin, E. Zampolli, C. Zaporozhets, S. Zarochentsev, A. Závada, P. Zbroszczyk, H. Zelnicek, P. Zenin, A. Zgura, I. Zhalov, M. Zhang, X. Zhou, D. Zichichi, A. Zinovjev, G. Zoccarato, Y. Zynovyev, M. The ALICE Collaboration
Subjects: High Energy Physics::Experiment, Nuclear Experiment
Abstract: The production of mesons containing strange quarks (K0 S, ϕ) and both singly and doubly strange baryons (⋀, ⊼, and Ξ− +Ξ+) are measured at mid-rapidity in pp collisions at √s = 0.9 TeV with the ALICE experiment at the LHC. The results are obtained from the analysis of about 250 k minimum bias events recorded in 2009. Measurements of yields (dN/dy) and transverse momentum spectra at mid-rapidity for inelastic pp collisions are presented. For mesons, we report yields (〈dN/dy〉) of 0.184 ± 0.002(stat.) ± 0.006(syst.) for K0 S and 0.021 ± 0.004(stat.) ± 0.003(syst.) for ϕ. For baryons, we find 〈dN/dy〉 = 0.048 ± 0.001(stat.) ± 0.004(syst.) for ⋀, 0.047 ± 0.002(stat.) ± 0.005(syst.) for ⊼ and 0.0101 ± 0.0020(stat.) ± 0.0009(syst.) for Ξ− +Ξ+. The results are also compared with predictions for identified particle spectra from QCD-inspired models and provide a baseline for comparisons with both future pp measurements at higher energies and heavy-ion collisions. © CERN for the benefit of the ALICE collaboration 2011.
Published: 2011

50. Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

Author: Strawbridge, R.J. Dupuis, J. Prokopenko, I. Barker, A. Ahlqvist, E. Rybin, D. Petrie, J.R. Travers, M.E. Bouatia-Naji, N. Dimas, A.S. Nica, A.C. Wheeler, E. Chen, H. Voight, B.F. Taneera, J. Kanoni, S. Peden, J.F. Turrini, F. Gustafsson, S. Zabena, C. Almgren, P. Barker, D.J.P. Barnes, D. Dennison, E.M. Eriksson, J.G. Eriksson, P. Eury, E. Folkersen, L. Fox, C.S. Frayling, T.M. Goel, A. Gu, H.F. Horikoshi, M. Isomaa, B. Jackson, A.U. Jameson, K.A. Kajantie, E. Kerr-Conte, J. Kuulasmaa, T. Kuusisto, J. Loos, R.J.F. Luan, J. Makrilakis, K. Manning, A.K. Martínez-Larrad, M.T. Narisu, N. Mannila, M.N. Öhrvik, J. Osmond, C. Pascoe, L. Payne, F. Sayer, A.A. Sennblad, B. Silveira, A. Stančcáková, A. Stirrups, K. Swift, A.J. Syvänen, A.-C. Tuomi, T. Van't Hooft, F.M. Walker, M. Weedon, M.N. Xie, W. Zethelius, B. Scott, L.J. Steinthorsdottir, V. Morris, A.P. Dina, C. Welch, R.P. Zeggini, E. Huth, C. Aulchenko, Y.S. Thorleifsson, G. Mcculloch, L.J. Ferreira, T. Grallert, H. Amin, N. Wu, G. Willer, C.J. Raychaudhuri, S. McCarroll, S.A. Hofmann, O.M. Qi, L. Segre, A.V. Van Hoek, M. Navarro, P. Ardlie, K. Balkau, B. Benediktsson, R. Bennett, A.J. Blagieva, R. Boerwinkle, E. Bonnycastle, L.L. Bostrom, K.B. Bravenboer, B. Bumpstead, S. Burtt, N.P. Charpentier, G. Chines, P.S. Cornelis, M. Couper, D.J. Crawford, G. Doney, A.S.F. Elliott, K.S. Elliott, A.L. Erdos, M.R. Franklin, C.S. Ganser, M. Gieger, C. Grarup, N. Green, T. Griffin, S. Groves, C.J. Guiducci, C. Hadjadj, S. Hassanali, N. Herder, C. Johnson, P.R.V. Jorgensen, T. Kao, W.H.L. Klopp, N. Kong, A. Kraft, P. Lauritzen, T. Li, M. Lieverse, A. Lindgren, C.M. Lyssenko, V. Marre, M. Meitinger, T. Midthjell, K. Morken, M.A. Nilsson, P. Owen, K.R. Perry, J.R.B. Petersen, A.-K. Platou, C. Proenca, C. Rathmann, W. Rayner, N.W. Robertson, N.R. Rocheleau, G. Roden, M. Sampson, M.J. Saxena, R. Shields, B.M. Shrader, P. Sigurdsson, G. Sparso, T. Strassburger, K. Stringham, H.M. Sun, Q. Thorand, B. Tichet, J. Van Dam, R.M. Van Haeften, T.W. Van Herpt, T. Van Vliet-Ostaptchouk, J.V. Walters, G.B. Wijmenga, C. Witteman, J.C.M. Bergman, R.N. Cauchi, S. Collins, F.S. Gloyn, A.L. Gyllensten, U. Hansen, T. Hide, W.A. Hitman, G.A. Hofman, A. Hunter, D.J. Hveem, K. Laakso, M. Mohlke, K.L. Morris, A.D. Palmer, C.N.A. Pramstaller, P.P. Rudan, I. Sijbrands, E. Stein, L.D. Tuomilehto, J. Uitterlinden, A.G. Wareham, N.J. Watanabe, R.M. Abecasis, G.R. Boehm, B.O. Campbell, H. Daly, M.J. Hattersley, A.T. Hu, F.B. Meigs, J.B. Pankow, J.S. Pedersen, O. Wichmann, H.-E. Barroso, I. Groop, L. Sladek, R. Thorsteinsdottir, U. Wilson, J.F. Illig, T. Froguel, P. Van Duijn, C.M. Stefansson, K. Altshuler, D. Boehnke, M. McCarthy, M.I. Speliotes, E.K. Berndt, S.I. Monda, K.L. Allen, H.L. Magi, R. Randall, J.C. Vedantam, S. Winkler, T.W. Workalemahu, T. Heid, I.M. Wood, A.R. Weyant, R.J. Estrada, K. Liang, L. Nemesh, J. Park, J.-H. Kilpelainen, T.O. Yang, J. Esko, T. Feitosa, M.F. Kutalik, Z. Mangino, M. Scherag, A. Smith, A.V. Zhao, J.H. Aben, K.K. Absher, D.M. Dixon, A.L. Fisher, E. Glazer, N.L. Goddard, M.E. Heard-Costa, N.L. Hoesel, V. Hottenga, J.-J. Johansson, A. Johnson, T. Ketkar, S. Lamina, C. Li, S. Moffatt, M.F. Myers, R.H. Peters, M.J. Preuss, M. Ripatti, S. Rivadeneira, F. Sandholt, C. Timpson, N.J. Tyrer, J.P. Van Wingerden, S. White, C.C. Wiklund, F. Barlassina, C. Chasman, D.I. Cooper, M.N. Jansson, J.-O. Lawrence, R.W. Pellikka, N. Shi, J. Thiering, E. Alavere, H. Alibrandi, M.T.S. Arnold, A.M. Aspelund, T. Atwood, L.D. Balmforth, A.J. Ben-Shlomo, Y. Bergmann, S. Biebermann, H. Blakemore, A.I.F. Boes, T. Bornstein, S.R. Brown, M.J. Buchanan, T.A. Busonero, F. Cappuccio, F.P. Cavalcanti-Proenca, C. Chen, Y.-D.I. Chen, C.-M. Clarke, R. Coin, L. Connell, J. Day, I.N.M. Den Heijer, M. Duan, J. Ebrahim, S. Elliott, P. Elosua, R. Eiriksdottir, G. Facheris, M.F. Felix, S.B. Fischer-Posovszky, P. Folsom, A.R. Friedrich, N. Freimer, N.B. Fu, M. Gaget, S. Gejman, P.V. Geus, E.J.C. Gjesing, A.P. Goyette, P. Grasler, J. Greenawalt, D.M. Gudnason, V. Hartikainen, A.-L. Hall, A.S. Havulinna, A.S. Hayward, C. Heath, A.C. Hengstenberg, C. Hicks, A.A. Hinney, A. Homuth, G. Hui, J. Igl, W. Iribarren, C. Jacobs, K.B. Jarick, I. Jewell, E. John, U. Jousilahti, P. Jula, A. Kaakinen, M. Kaplan, L.M. Kathiresan, S. Kettunen, J. Kinnunen, L. Knowles, J.W. Kolcic, I. König, I.R. Koskinen, S. Kovacs, P. Kvaloy, K. Laitinen, J. Lantieri, O. Lanzani, C. Launer, L.J. Lecoeur, C. Lehtimaki, T. Lettre, G. Liu, J. Lokki, M.-L. Lorentzon, M. Luben, R.N. Ludwig, B. Manunta, P. Marek, D. Martin, N.G. McArdle, W.L. McCarthy, A. McKnight, B. Melander, O. Meyre, D. Montgomery, G.W. Mulic, R. Ngwa, J.S. Nelis, M. Neville, M.J. Nyholt, D.R. O'Donnell, C.J. O'Rahilly, S. Ong, K.K. Oostra, B. Pare, G. Parker, A.N. Perola, M. Pichler, I. Pietilainen, K.H. Platou, C.G.P. Polasek, O. Pouta, A. Rafelt, S. Raitakari, O. Rayner, N.W. Ridderstrale, M. Rief, W. Ruokonen, A. Rzehak, P. Salomaa, V. Sanders, A.R. Sandhu, M.S. Sanna, S. Saramies, J. Savolainen, M.J. Scherag, S. Schipf, S. Schreiber, S. Schunkert, H. Silander, K. Sinisalo, J. Siscovick, D.S. Smit, J.H. Soranzo, N. Sovio, U. Stephens, J. Surakka, I. Tammesoo, M.-L. Tardif, J.-C. Teder-Laving, M. Teslovich, T.M. Thompson, J.R. Thomson, B. Tonjes, A. Van Meurs, J.B.J. Van Ommen, G.-J. Vatin, V. Viikari, J. Visvikis-Siest, S. Vitart, V. Vogel, C.I.G. Waite, L.L. Wallaschofski, H. Widen, E. Wiegand, S. Wild, S.H. Willemsen, G. Witte, D.R. Xu, J. Zhang, Q. Zgaga, L. Ziegler, A. Zitting, P. Beilby, J.P. Farooqi, I.S. Hebebrand, J. Huikuri, H.V. James, A.L. Kahonen, M. Levinson, D.F. Macciardi, F. Nieminen, M.S. Ohlsson, C. Palmer, L.J. Ridker, P.M. Stumvoll, M. Beckmann, J.S. Boeing, H. Boomsma, D.I. Caulfield, M.J. Chanock, S.J. Cupples, L.A. Smith, G.D. Erdmann, J. Gronberg, H. Hall, P. Harris, T.B. Hayes, R.B. Heinrich, J. Jarvelin, M.-R. Kaprio, J. Karpe, F. Khaw, K.-T. Kiemeney, L.A. Krude, H. Lawlor, D.A. Metspalu, A. Munroe, P.B. Ouwehand, W.H. Penninx, B.W. Peters, A. Quertermous, T. Reinehr, T. Rissanen, A. Samani, N.J. Schwarz, P.E.H. Shuldiner, A.R. Spector, T.D. Uda, M. Valle, T.T. Wabitsch, M. Waeber, G. Watkins, H. Wright, A.F. Zillikens, M.C. Chatterjee, N. Purcell, S. Schadt, E.E. Visscher, P.M. Assimes, T.L. Borecki, I.B. Deloukas, P. Haritunians, T. Kaplan, R.C. O'Connell, J.R. Peltonen, L. Schlessinger, D. Strachan, D.P. North, K.E. Hirschhorn, J.N. Ingelsson, E. Parts, L. Glass, D. Nisbet, J. Barrett, A. Sekowska, M. Potter, S. Grundberg, E. Small, K. Hedman, A.K. Bataille, V. Bell, J.T. Surdulescu, G. Ingle, C. Nestle, F.O. Di Meglio, P. Min, J.L. Wilk, A. Hammond, C.J. Yang, T.-P. Montgomery, S.B. Zondervan, K.T. Durbin, R. Ahmadi, K. Dermitzakis, E.T. Reilly, M.P. Holm, H. Stewart, A.F.R. Barbalic, M. Aherrahrou, Z. Allayee, H. Anand, S.S. Andersen, K. Anderson, J.L. Ardissino, D. Ball, S.G. Barnes, T.A. Becker, D.M. Becker, L.C. Berger, K. Bis, J.C. Boekholdt, S.M. Braund, P.S. Burnett, M.S. Buysschaert, I. Carlquist, J.F. Chen, L. Codd, V. Davies, R.W. Cichon, S. Dedoussis, G.V. Demissie, S. Dehghan, A. Devaney, J.M. Diemert, P. Do, R. Doering, A. Eifert, S. El Mokhtari, N.E. Ellis, S.G. Engert, J.C. Epstein, S.E. De Faire, U. Fischer, M. Freyer, J. Gigante, B. Girelli, D. Gretarsdottir, S. Gulcher, J.R. Halperin, E. Hammond, N. Hazen, S.L. Horne, B.D. Jones, G.T. Jukema, J.W. Kaiser, M.A. Kastelein, J.J.P. Kolovou, G. Laaksonen, R. Lambrechts, D. Leander, K. Li, M. Lieb, W. Loley, C. Lotery, A.J. Mannucci, P.M. Maouche, S. Martinelli, N. McKeown, P.P. Meisinger, C. Merlini, P.A. Mooser, V. Morgan, T. Mühleisen, T.W. Muhlestein, J.B. Münzel, T. Musunuru, K. Nahrstaedt, J. Nelson, C.P. Nöthen, M.M. Olivieri, O. Patel, R.S. Patterson, C.C. Peyvandi, F. Qu, L. Quyyumi, A.A. Rader, D.J. Rallidis, L.S. Rice, C. Rosendaal, F.R. Rubin, D. Sampietro, M.L. Sandhu, M.S. Schadt, E. Schäfer, A. Schillert, A. Schrezenmeir, J. Schwartz, S.M. Sivananthan, M. Sivapalaratnam, S. Smith, T.B. Snoep, J.D. Spertus, J.A. Stark, K. Stoll, M. Wilson Tang, W.H. Tennstedt, S. Thorgeirsson, G. Tomaszewski, M. Van Rij, A.M. Wells, G.A. Wild, P.S. Willenborg, C. Wright, B.J. Ye, S. Zeller, T. Cambien, F. Goodall, A.H. Marz, W. Blankenberg, S. Roberts, R. McPherson, R. Hopewell, J.C. Parish, S. Offer, A. Bowman, L. Sleight, P. Armitage, J. Peto, R. Collins, R. Chambers, J.C. Ahmed, N. Donnelly, P. Kooner, A.S. Scott, J. Sehmi, J. Zhang, W. Kooner, J. Sabater-Lleal, M. Mälarstig, A. Hellénius, M.-L. Olsson, G. Rust, S. Assmann, G. Seedorf, U. Barlera, S. Tognoni, G. Franzosi, M.G. Linksted, P. Ongen, H. Kyriakou, T. Green, F. Farrall, M. Saleheen, D. Rasheed, A. Zaidi, M. Shah, N. Samuel, M. Mallick, N. Azhar, M. Zaman, K. Samad, A. Ishaq, M. Gardezi, A. Memon, F.-U.-R. Frossard, P. Danesh, J. Östenson, C.-G. Lind, L. Cooper, C.C. Serrano-Ríos, M. Ferrannini, E. Forsen, T.J. Pattou, F. Langenberg, C. Hamsten, A. Florez, J.C.
Subjects: endocrine system, endocrine system diseases, nutritional and metabolic diseases
Abstract: OBJECTIVE - Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating proinsulin levels are associated with impaired b-cell function, raised glucose levels, insulin resistance, and type 2 diabetes (T2D). Studies of the insulin processing pathway could provide new insights about T2D pathophysiology. RESEARCH DESIGN AND METHODS - We have conducted a meta-analysis of genome-wide association tests of ;2.5 million genotyped or imputed single nucleotide polymorphisms (SNPs) and fasting proinsulin levels in 10,701 nondiabetic adults of European ancestry, with follow-up of 23 loci in up to 16,378 individuals, using additive genetic models adjusted for age, sex, fasting insulin, and study-specific covariates. RESULTS - Nine SNPs at eight loci were associated with proinsulin levels (P < 5 × 10-8). Two loci (LARP6 and SGSM2) have not been previously related to metabolic traits, one (MADD) has been associated with fasting glucose, one (PCSK1) has been implicated in obesity, and four (TCF7L2, SLC30A8, VPS13C/ C2CD4A/B, and ARAP1, formerly CENTD2) increase T2D risk. The proinsulin-raising allele of ARAP1 was associated with a lower fasting glucose (P = 1.7 3 10-4), improved b-cell function (P = 1.1 × 10-5), and lower risk of T2D (odds ratio 0.88; P = 7.8 × 10-6). Notably, PCSK1 encodes the protein prohormone convertase 1/3, the first enzyme in the insulin processing pathway. A genotype score composed of the nine proinsulin-raising alleles was not associated with coronary disease in two large case-control datasets. CONCLUSIONS - We have identified nine genetic variants associated with fasting proinsulin. Our findings illuminate the biology underlying glucose homeostasis and T2D development in humans and argue against a direct role of proinsulin in coronary artery disease pathogenesis. © 2011 by the American Diabetes Association.
Published: 2011

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