6 results on '"José Benjamín Guerrero López"'
Search Results
2. Study protocol for pragmatic trials of Internet-delivered guided and unguided cognitive behavior therapy for treating depression and anxiety in university students of two Latin American countries: the Yo Puedo Sentirme Bien study
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Corina Benjet, Ronald C. Kessler, Alan E. Kazdin, Pim Cuijpers, Yesica Albor, Nayib Carrasco Tapias, Carlos C. Contreras-Ibáñez, Ma Socorro Durán González, Sarah M. Gildea, Noé González, José Benjamín Guerrero López, Alex Luedtke, Maria Elena Medina-Mora, Jorge Palacios, Derek Richards, Alicia Salamanca-Sanabria, and Nancy A. Sampson
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Depression ,Anxiety ,iCBT ,Latin America ,College students ,Precision treatment algorithm ,Medicine (General) ,R5-920 - Abstract
Abstract Background Major depressive disorder (MDD) and generalized anxiety disorder (GAD) are highly prevalent among university students and predict impaired college performance and later life role functioning. Yet most students do not receive treatment, especially in low-middle-income countries (LMICs). We aim to evaluate the effects of expanding treatment using scalable and inexpensive Internet-delivered transdiagnostic cognitive behavioral therapy (iCBT) among college students with symptoms of MDD and/or GAD in two LMICs in Latin America (Colombia and Mexico) and to investigate the feasibility of creating a precision treatment rule (PTR) to predict for whom iCBT is most effective. Methods We will first carry out a multi-site randomized pragmatic clinical trial (N = 1500) of students seeking treatment at student mental health clinics in participating universities or responding to an email offering services. Students on wait lists for clinic services will be randomized to unguided iCBT (33%), guided iCBT (33%), and treatment as usual (TAU) (33%). iCBT will be provided immediately whereas TAU will be whenever a clinic appointment is available. Short-term aggregate effects will be assessed at 90 days and longer-term effects 12 months after randomization. We will use ensemble machine learning to predict heterogeneity of treatment effects of unguided versus guided iCBT versus TAU and develop a precision treatment rule (PTR) to optimize individual student outcome. We will then conduct a second and third trial with separate samples (n = 500 per arm), but with unequal allocation across two arms: 25% will be assigned to the treatment determined to yield optimal outcomes based on the PTR developed in the first trial (PTR for optimal short-term outcomes for Trial 2 and 12-month outcomes for Trial 3), whereas the remaining 75% will be assigned with equal allocation across all three treatment arms. Discussion By collecting comprehensive baseline characteristics to evaluate heterogeneity of treatment effects, we will provide valuable and innovative information to optimize treatment effects and guide university mental health treatment planning. Such an effort could have enormous public-health implications for the region by increasing the reach of treatment, decreasing unmet need and clinic wait times, and serving as a model of evidence-based intervention planning and implementation. Trial status IRB Approval of Protocol Version 1.0; June 3, 2020. Recruitment began on March 1, 2021. Recruitment is tentatively scheduled to be completed on May 30, 2024. Trial registration ClinicalTrials.gov NCT04780542 . First submission date: February 28, 2021.
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- 2022
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3. Evaluation of quality of life and depression in patients with rheumatoid arthritis in a General Hospital
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José Benjamín Guerrero-López, Ricardo Ortiz García, Danelia Mendieta Cabrera, and María del Carmen Lara-Muñoz
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030203 arthritis & rheumatology ,medicine.medical_specialty ,Visual analogue scale ,business.industry ,Beck Depression Inventory ,General Medicine ,medicine.disease ,Comorbidity ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,Rheumatoid arthritis ,Physical therapy ,Outpatient clinic ,Medicine ,030212 general & internal medicine ,business ,Rheumatism ,Depression (differential diagnoses) - Abstract
Introduction Rheumatoid arthritis (RA) is a chronic, inflammatory, and multisystemic disease that has an impact on the quality of life and is associated with depressive symptoms. Objectives To evaluate the quality of life, overall health status, and depression in patients with RA. Patients and methods A cross-sectional study was conducted in the outpatient Rheumatology Outpatient Department of a General Hospital in Mexico City. All patients met the criteria for rheumatoid arthritis according to the American Rheumatism Association, 1987. Clinical and sociodemographic characteristics were recorded. Four measurement tools were used: Arthritis Impact Measurement Scale (AIMS), Dunbar Questionnaire, a Visual Analog Scale, and the Beck Depression Inventory. Results A total of 43 patients aged ≥ 18 years were evaluated. The highest AIMS scores were in social activity (6.49±1.93), pain (4.70±2.04), depression (4.70±2.23), and physical activity (4.03±2.10). The mean score with the Dunbar questionnaire was 6.48±1.87, the mean Visual Analog Scale score was 69.41±24.67, and the mean of the Beck inventory was 15.74±9.85. Conclusions The presence of anxiety and depression has an impact on the quality of life of patients with RA, but not on the presence of comorbidity or disease activity. Depressive symptoms are common in patients with RA, and should therefore be considered when evaluating this rheumatological disease.
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- 2017
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4. Evaluation of trait and state anxiety levels in a group of peri- and postmenopausal women
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Margus Salinas, Mónica Flores-Ramos, José Benjamín Guerrero-López, and Roberto Silvestri Tomassoni
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Adult ,medicine.medical_specialty ,Peri ,Anxiety ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,medicine ,Humans ,Aged ,030219 obstetrics & reproductive medicine ,Postmenopausal women ,Obstetrics ,General Medicine ,Middle Aged ,Perimenopause ,Postmenopause ,Cross-Sectional Studies ,Hot Flashes ,Trait ,Hormonal therapy ,Female ,medicine.symptom ,Psychology ,030217 neurology & neurosurgery ,Clinical psychology - Abstract
Our objective was to evaluate levels of trait and state anxiety in a group of peri- and postmenopausal women and to explore the relation of hormonal therapy to levels of anxiety. Peri- (n = 63) and postmenopausal (n = 236) women were evaluated between March and September 2013. The assessed variables were menopausal status, anxiety (using the state and trait anxiety inventory), and sociodemographic and clinical variables. Use of psychotropic medications and hormone therapy was also ascertained. The mean age of the participants was 51.9 years, ranging from 31 to 69 years. The mean state anxiety scores, as well as the mean trait anxiety scores, were higher in perimenopausal than postmenopausal women. High state anxiety (above the 75th percentile), but not high trait anxiety, was related to perimenopausal status. Anxiety levels appeared to be higher among perimenopausal than postmenopausal women, as also occurs with depressive symptoms. Anxiety state provides data about recent anxiety symptoms in women; however, anxiety trait could be present in some women before perimenopause. Our findings suggest that perimenopause is a period with increased anxiety levels in some women.
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- 2017
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5. Evaluation of quality of life and depression in patients with rheumatoid arthritis in a General Hospital
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María del Carmen Lara-Muñoz, José Benjamín Guerrero-López, Ricardo Ortiz García, and Danelia Mendieta Cabrera
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030203 arthritis & rheumatology ,0301 basic medicine ,Quality of life ,business.industry ,Depression ,Calidad de vida ,Artritis reumatoide ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Rheumatology ,Depresión ,Medicine ,Rheumatoid arthritis ,business ,Humanities - Abstract
Introduction: Rheumatoid arthritis (RA) is a chronic, inflammatory, and multisystemic disease that has an impact on the quality of life and is associated with depressive symptoms. Objectives: To evaluate the quality of life, overall health status, and depression in patients with RA. Patients and methods: A cross-sectional study was conducted in the outpatient Rheumatology Outpatient Department of a General Hospital in Mexico City. All patients met the criteria for rheumatoid arthritis according to the American Rheumatism Association, 1987. Clinical and sociodemographic characteristics were recorded. Four measurement tools were used: Arthritis Impact Measurement Scale (AIMS), Dunbar Questionnaire, a Visual Analog Scale, and the Beck Depression Inventory. Results: A total of 43 patients aged ≥ 18 years were evaluated. The highest AIMS scores were in social activity (6.49±1.93), pain (4.70±2.04), depression (4.70±2.23), and physical activity (4.03±2.10). The mean score with the Dunbar questionnaire was 6.48±1.87, the mean Visual Analog Scale score was 69.41±24.67, and the mean of the Beck inventory was 15.74±9.85. Conclusions: The presence of anxiety and depression has an impact on the quality of life of patients with RA, but not on the presence of comorbidity or disease activity. Depressive symptoms are common in patients with RA, and should therefore be considered when evaluating this rheumatological disease. resumen Introducción: La artritis reumatoide (AR) es una enfermedad que afecta la calidad de vida de quienes la padecen y se asocia a sintomatologia depresiva. Objetivos: Evaluar la calidad de vida, el estado global de salud y depresión en pacientes con AR. Pacientes y métodos: Se trata de un estudio transversal y comparativo. Se incluyeron 43 adultos mayores, ≥ de 18 anos, con diagnóstico de AR según los criterios de la American Rheumatism Association de 1987, que acudían al servicio de consulta externa de Reumatologia de un hospital general en la ciudad de México. Se determinaron características clínicas y sociodemográficas. Se les aplicaron 4 índices: Escala de Medición del Impacto de la Artritis (AIMS), Cuestionario de Dunbar, Escala Análoga Visual y el Inventario de Depresión de Beck. Resultados: Se evaluaron 43 pacientes mayores de 18 anos, en su mayoría del sexo femenino. Para la AIMS, las puntuaciones más altas fueron en actividad social (6, 49 ± 1, 93), dolor (4,70 ± 2,04), depresión (4,70 ± 2,23) y actividad física (4,03 ± 2,10). Para el cuestionario de Dunbar la puntuación promedio fue de 6, 48 ± 1, 87, en la escala análoga visual la puntuación media fue de 69,41 ± 24,67, finalmente, en el inventario de Beck el promedio fue de 15,74 ±9,85. Conclusiones: La presencia de ansiedad y depresión se relacionan con la calidad de vida de los pacientes con AR mas no con la presencia de comorbilidad o actividad de la enfermedad. Los síntomas depresivos son comunes en pacientes con AR por lo que deben considerarse al evaluar esta enfermedad reumatológica.
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- 2017
6. [Factors that predict depression in medical students]
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José Benjamín, Guerrero López, Gerardo, Heinze Martin, Silvia, Ortiz de León, Jacqueline, Cortés Morelos, Virginia, Barragán Pérez, and Mónica, Flores-Ramos
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Male ,Young Adult ,Students, Medical ,Adolescent ,Depression ,Risk Factors ,Humans ,Female ,Forecasting - Abstract
High prevalence of depression and anxiety symptoms has been observed in medical students.To identify predictors of depressive symptoms according to CES-D in students during their first year of medical education.We evaluated 517 students in their first year of medical education with the following instruments: Centers for Epidemiology Studies for Depression Scale, State-Trait anxiety inventory, and stressors list. A linear regression analysis was carried out to evaluate variables predicting high CES-D scores.We observed that anxiety and depressive symptoms were more frequent in women, as well as stressors. Predictors of depression were state of anxiety, stressors, and low socioeconomic level.It is important to implement support measures for students who live with stress factors, suffering anxiety, or with a low socioeconomic level.
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- 2013
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