1. Correlations Between Cutaneous Malignant Melanoma and Other Cancers: An Ecological Study in Forty European Countries
- Author
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José Luis Fernández-Crehuet Serrano, Rafael Fernández-Crehuet Navajas, Pablo Fernández-Crehuet Serrano, Mohamed Farouk Allam, [Serrano, Pablo Fernandez-Crehuet] Reina Sofia Univ Hosp, IMIBIC, Dept Dermatol, Cordoba, Spain, [Serrano, Jose Luis Fernandez-Crehuet] Alto Guadalquivir Hosp, Dept Dermatol, Jaen, Spain, [Allam, Mohamed Farouk] Univ Cordoba, Dept Prevent Med & Publ Hlth, Fac Med, Avenida Menendez Pidal,s n, Cordoba 14004, Spain, and [Navajas, Rafael Fernandez-Crehuet] Univ Cordoba, Dept Prevent Med & Publ Hlth, Fac Med, Avenida Menendez Pidal,s n, Cordoba 14004, Spain
- Subjects
Oncology ,Risk ,medicine.medical_specialty ,Colorectal cancer ,Estrogen-receptor ,United-states ,lcsh:Medicine ,Brief Communication ,Pooled analysis ,Association ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,Skin-cancer ,Internal medicine ,Epidemiology of cancer ,Carcinoma ,medicine ,Genetics ,ecological ,melanoma ,Testicular cancer ,Cancer ,Progression ,business.industry ,Melanoma ,Incidence (epidemiology) ,lcsh:R ,Public Health, Environmental and Occupational Health ,medicine.disease ,Non-hodgkins-lymphoma ,030220 oncology & carcinogenesis ,incidence ,epidemiology ,business ,Oral-contraceptive use - Abstract
Background: The presence of noncutaneous neoplasms does not seem to increase the risk of cutaneous malignant melanoma; however, it seems to be associated with the development of other hematological, brain, breast, uterine, and prostatic neoplasms. An ecological transversal study was conducted to study the geographic association between cutaneous malignant melanoma and 24 localizations of cancer in forty European countries. Methods: Cancer incidence rates were extracted from GLOBOCAN database of the International Agency for Research on Cancer. We analyzed the age-adjusted and gender-stratified incidence rates for different localizations of cancer in forty European countries and calculated their correlation using Pearson's correlation test. Results: In males, significant correlations were found between cutaneous malignant melanoma with testicular cancer (r = 0.83 [95% confidence interval (CI): 0.68-0.89]), myeloma (r = 0.68 [95% CI: 0.46-0.81]), prostatic carcinoma (r = 0.66 [95% CI: 0.43-0.80]), and non-Hodgkin lymphoma (NHL) (r = 0.63 [95% CI: 0.39-0.78]). In females, significant correlations were found between cutaneous malignant melanoma with breast cancer (r = 0.80 [95% CI: 0.64-0.88]), colorectal cancer (r = 0.72 [95% CI: 0.52-0.83]), and NHL (r = 0.71 [95% CI: 0.50-0.83]). Conclusions: These correlations call to conduct new studies about the epidemiology of cancer in general and cutaneous malignant melanoma risk factors in particular.
- Published
- 2016