1. Coxsackievirus A24 causing acute conjunctivitis in a 2023 outbreak in Vietnam
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Huy Tran, Thao Ha, Linh Hoang, Yen Tran, Kevin Ruder, Lina Zhong, Cindi Chen, YuHeng Liu, Danny Yu, Thomas Abraham, Armin Hinterwirth, Michael Deiner, Travis C. Porco, Thomas M. Lietman, Thuy Doan, Gerami D. Seitzman, Lalitha Prajna, N. Venkatesh Prajna, Ramesh Gunasekaran, Sankalp Singh Sharma, Vishnu Teja, Meenu Chaudhary, Sanjeeta Sitaula, Ali Sié, Boubacar Coulibaly, Mamadou Bountogo, Thanapong Somkijrungroj, Vannarut Satitpitakul, Linh Hoàng Mai, Thảo Hạ Xuân, Cristhian A. Urzua, Fabian Vega, Felipe Salgado, Loreto Cuitino, Fernando Pérez Pérez, Jaime Macías Martínez, Van Charles Lansingh, Sukhumal Thanapaisal, Wipada Laovirojjanakul, George McKie, Program Officer, Kenia Chavez, Travis Redd, Winston Chamberlain, Angel Cheng, Vivien Tham, Wiwan Sansanayudh, Abba Kaka Hajia Yakoura, Abdou Amza, Abdoul Salam Youssoufou Souley, Adam Nouhou Diori, Beido Nassirou, Boubacar Kadri, Boubacar Mariama, Cissé Mamadou Ibrahim, Lamyne Aboubacar Roufaye, Ramatou Boulhassane, Saley Ali, Zakou Abdou, Lee Goren, Irit Bahar, Ruti Sella, Clare Kelliher, Laura Green, Hon Shing Ong, Jod Mehta, Yu-Chi Liu, Benjamin A. Pinsky, De-Kuang Hwang, Nai-Wen Fan, Hong Sheng Chiong, Javier Lacorzana, Maria Cabrera-Aguas, Stephanie Watson, Edmund Tsui, Nina M. Cherian, Rachel Feit-Leichman, Reginald E. Hughes, Jr, Tania Onclinx, Joseph K Privratsky, Carol Yu, Esmeralda McClean, Iliana Molina, David Liu, Elodie Lebas, Emily Colby, Gerami Seitzman, Thomas Lietman, Thuy Doan, Principal Investigator, Travis Porco, Stephen McLeod, Kuniyoshi Kanai, Meredith Whiteside, Steven Yeh, Tolulope Fashina, James Chodosh, Bridgit Tarkap, Jambi N. Garap, Magdalene Mangot, Edwin Amel, Fasihah Taleo, Johnson Kasso, Kalbule Willie, Madopule Nanu, Prudence Rymill, and Anthony W. Solomon
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Coxsackievirus ,Epidemic ,Conjunctivitis ,Keratoconjunctivitis (EKC) ,Vietnam ,Infectious and parasitic diseases ,RC109-216 - Abstract
Objectives: To determine the associated pathogen during the 2023 conjunctivitis outbreak in Vietnam Methods: RNA-sequencing was used to identify pathogens before and during the outbreak. Results: 24 patients with infectious conjunctivitis between March and October 2023 from Hai Yen Vision Institute in Vietnam were swabbed. Coxsackievirus A24v was the most common pathogen identified. Phylogenetic analysis of these strains demonstrates similarities to the Coxsackievirus identified in the 2022 India outbreak. Human adenovirus D was also circulating. Ocular findings of tearing, purulence, and itching were common in this outbreak. Conclusions: Multiple viruses can co-circulate during conjunctivitis outbreaks. Hemorrhagic conjunctivitis, commonly associated with coxsackievirus conjunctivitis, was not a common clinical sign in this outbreak. Repeat genetic surveillance, with the notable inclusion of RNA virus detection strategies, is important for outbreak detection.
- Published
- 2024
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