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7 results on '"Joseph Polito"'

2. Peginterferon alfa-2b and weight-based or flat-dose ribavirin in chronic hepatitis C patients: A randomized trial

Author

Stuart C. Gordon, Rvikumar Vemuru, Mark Eisner, Jay Cowan, James Ehrlich, Alain Ades, Clifford A. Brass, Micheal David Bernstein, Steve Chen, Donald Hillebrand, Donald Wadland, Lyle Shlager, C. Smith, Lou Gelrud, Mark Levstik, Helen Wong, Stephen A. Harrison, Andrew Nelson, Raj Bhandari, David Dies, Mordechai Rabinovitz, Edward A. Galen, B. Freilich, K. Digregorio, Curt Hagendom, Thomas Hargrave, Paul Bermanski, David Maccini, Samuel B. Ho, Ronald Pruitt, Terence Reisman, Thomas Allen, Robert S. Brown, Michael Cox, David Schulman, Ramsey Cheung, Fred Kilby, J. Lynn Cochran, Thomas McDonald, James Thornton, John Jolley, John Serini, Albert D. Min, Fredrich Loura, Lino Deguzman, Luis Marsano, Robert Finkel, Helen S. Te, Michael G Rahmin, Mark Jonas, Kip Lyche, Jean Luc Szpakowski, George Abraham, Alex D. Lee, Pabak Mukhopadhyay, Firdous Siddiqui, Robert Strauss, William Kaplan, Michael Ryan, Eliot Godofsky, Stephen J. Lanspa, Lawton Shick, Jose Franco, Louis Griffel, Rise Stribling, Avanish Aggarwal, Clive Albert, Thomas Rosenfield, Rockford Yapp, Vijay Balan, Arthur Berman, Nezam H. Afdhal, Maurice Cerulli, Paul Yudelman, Robert Herring, Donate Ricci, Michael Henry, Michael Bloom, Daniel Meline, Barry Migicovsky, Peter Varunok, Peter W Gardner, Gerald Siciliano, Natarjan Bala, Craig J. Peine, P. Kwo, Thomas Noble, David F. Stein, Thuan T. Nguyen, Geoffrey Zucker, Julie E Spivack, John Kichner, Robert G. Gish, Michael Fried, Murali Shankar, Norman Gitlin, James E. Nelson, David Hurwich, Darrell Schwertner, Ronald Wasserman, Douglas D. Dalke, Thai Van Pham, Geronimo Sahagun, Norah A. Terrault, Naoky Tsai, Steven Han, Tarek Hassanein, Thomas Sepe, Seth Richter, Howard Paul Monsour, Micheal Lyons, R. Agrawal, Bennett Cecil, Joseph Polito, Douglas Levin, James Srour, Allan Weston, Larry Weprin, Raymond Kenny, Edward Lebovics, Michael Demicco, Terry Box, Kenneth Diamond, Lawrence Kim, Stephen Kelly, Martin Black, Jeffrey Fenyves, Ellen Shaw, Raymond A. Rubin, James E. Cox, Franco Felizarta, John E. Gross, Ira Lobis, David H. Van Thiel, Bonnie Bock, Lawrence Stein, James D. Lewis, Steven Palley, Ronald Rinker, Joanna Ready, Vinod K. Rustgi, Michael Epstein, David H Berman, Gary Matusow, Walid Baddoura, Gerond Lake-Bakaar, John S. Goff, Scott Wiesen, Neil Brodsky, Fredric Regenstein, Arnold Levin, Bhupinder S. Anand, Stephen Esposito, K. Rajender Reddy, Lisa Ozick, Adil E. Wakil, Karl Esrason, Pierre Nader, David Nunes, David Feldman, K. Ganeshappa, Alan Fixelle, Martha Ghosh, Douglas Brouillette, Victor Araya, Hillel Tobias, David Pound, Louis R. Lambiase, S. Lawrence Rothman, Mark J. Murphy, Jonathan David, James Levin, Steve Carlson, Nathan Kam, Michael S. Dragutsky, Trong Nguyen Tuan, Graham Woolf, Whit Knapple, Donna Goldman, Kenneth R. DeVault, Simon Cofrancesco, Mitchell L. Shiffman, Charles Bedard, Paul Y. Kwo, Rodger Perez, Steven L. Flamm, Keith Tolman, Hulya Levendoglu, Timothy Cavacini, Robert Reindollar, Vance VanDrake, Donald M. Jensen, David Winston, Robert A. Levine, Robert Manning, John R. Lake, John J. Santoro, Scott Becker, Mary Pat Pauly, John M. Vierling, Joseph DePasquale, Jorge Herrera, Diana Sylvestre, Natarajan Ravendhran, Mark Smith, Kevin Dye, M. Davis, Frank Klion, Kevin Behrle, Alan Epstein, William Lyles, Brian K. Hudes, Greg Galler, David I. Bernstein, Jonathon Jensen, Jeffery Cooley, Thomas J. Layden, Carl D'Angelo, Fredric D. Gordon, Myron Brand, David Gabbazaideh, Leon Rigberg, Neville R. Pimstone, Jonathan McCone, Ira M. Jacobson, Tim M Jenkins, John W. King, Harry Matossian, William A. Ross, and Rudra Rai

Subjects
Adult, Male, medicine.medical_specialty, Adolescent, Genotype, Hepatitis C virus, Alpha interferon, Hepacivirus, Interferon alpha-2, medicine.disease_cause, Antiviral Agents, Gastroenterology, Polyethylene Glycols, chemistry.chemical_compound, Pegylated interferon, Internal medicine, Ribavirin, medicine, Humans, Prospective Studies, Interferon alfa, Aged, Dose-Response Relationship, Drug, Hepatology, business.industry, Body Weight, Interferon-alpha, Middle Aged, Hepatitis C, Recombinant Proteins, Surgery, Treatment Outcome, chemistry, RNA, Viral, Peginterferon alfa-2b, Drug Therapy, Combination, Female, business, Viral load, medicine.drug
Abstract

This prospective, multicenter, community-based and academic-based, open-label, investigator-initiated, U.S. study evaluated efficacy and safety of pegylated interferon (PEG-IFN) alfa-2b plus a flat or weight-based dose of ribavirin (RBV) in adults with chronic hepatitis C. Patients (n = 5027) were randomly assigned to receive PEG-IFN alfa-2b 1.5 μg/kg/week plus flat-dose (800 mg/day) or weight-based (800-1400 mg/day) RBV for 48 weeks (patients with genotype 1, 4, 5, or 6) and for 24 or 48 weeks (genotype 2/3 patients). Primary end point was sustained virologic response (undetectable [

Published
2007

3. Factors predictive of difficult colonoscopy

Author

Edward B. Gottfried, Gary Bernstein, William E. Cohn, Joseph Polito, Joseph C. Anderson, Scott Ingber, Eugene Coman, and Catherine R. Messina

Subjects
Male, medicine.medical_specialty, Time Factors, Constipation, medicine.medical_treatment, Laxative, Colonoscopy, Disease, Body Mass Index, Sex Factors, Risk Factors, medicine, Humans, Intubation, Radiology, Nuclear Medicine and imaging, Prospective Studies, Prospective cohort study, medicine.diagnostic_test, business.industry, General surgery, Age Factors, Gastroenterology, Middle Aged, Surgery, Logistic Models, Diverticular disease, Feasibility Studies, Female, Clinical Competence, medicine.symptom, business, Body mass index
Abstract

Background: Prediction of a technically difficult colonoscopy may influence patient selection and procedure scheduling. Identification of predictive factors may be difficult because a common endpoint used to evaluate the success of colonoscopy is intubation of the cecum, which is usually achieved. The goal of this study was to examine the feasibility of using an alternative measure, time required for cecal intubation, to identify factors that can impact performance of colonoscopy. Methods: The time required for cecal intubation was prospectively recorded for 802 consecutive outpatient colonoscopies performed by 7 experienced gastroenterologists. Patient data collected included height, weight, age, bowel habits, surgical history, and findings at colonoscopy. Forty-seven examinations that were stopped because of disease or unacceptable bowel preparation were excluded. The impact of the patient characteristics of the remaining sample of 755 patients on the median time required for cecal intubation for men and women was examined. Results: Older age and female gender, body mass index ≤25.0 (regardless of gender), diverticular disease in women, and a history of constipation or reported laxative use in men were predictors of difficult colonoscopy. Conclusions: By using median time required for cecal intubation, several patient characteristics were identified that may predict technical difficulty at colonoscopy. These findings have implications for practice and teaching. (Gastrointest Endosc 2001;54:558-62.)

Published
2001

5. SNAP/SOS: A package for simulating and analyzing safeguards systems

Author

Jerome Sabuda, Joseph Polito, and Floyd H. Grant

Subjects
Engineering, business.industry, Control (management), Snap, ComputerApplications_COMPUTERSINOTHERSYSTEMS, Simulation system, computer.software_genre, Computer Graphics and Computer-Aided Design, Nuclear facilities, Computer graphics, Modeling and Simulation, Operating system, Graphics, business, Software engineering, computer, Software, Network analysis
Abstract

The effective analysis of safeguards systems at nuclear facilities requires significant effort. The Safeguards Network Analysis Pro cedure (SNAP) and the SNAP Operating System (SOS) reduce that effort to a manageable level. SNAP provides a detailed analysis of site safeguards for tactical evaluation. SOS helps the analyst organize and manage the SNAP effort effectively. SOS provides a database for model storage, automatic model genera tion, and computer graphics. The SOS/SNAP combination is a working example of a simulation system including executive- level control, database system, and facilities for model creation, editing, and output analysis.

Published
1983

6. A Computer Simulation of Visual Recognition Performance

Author

Valerie J. Gawron, Joseph Polito, K. Ronald Laughery, and Charles C. Jorgensen

Subjects
Engineering, Operator performance, Variables, Injury control, business.industry, media_common.quotation_subject, Poison control, General Medicine, Observer (special relativity), Distance to target, Time on task, Visual recognition, Computer vision, Artificial intelligence, business, Simulation, media_common
Abstract

As part of an ongoing program to develop computer models of human performance (MOPADS, Model of Operator Performance in Air Defense Systems), a computer model of visual recognition performance was developed. The model predicts the probability of an observer detecting and recognizing a target as a function of several independent variables. The values of these variables can be defined by the user (e.g., number of observers, observer's time on task) or be provided from an ongoing simulation of an air defense scenario (e.g., distance to target, target speed).

Published
1983

7. Solution of Spatial Equilibrium Problems with Benders Decomposition

Author

Bruce A. McCarl, Joseph Polito, and Thomas L. Morin

Subjects
Mathematical logic, Mathematical optimization, nonlinear [economics, planning, programming], Mathematical model, Linear programming, Iterative method, Strategy and Management, Quadratic programming, Management Science and Operations Research, Benders' decomposition, Spatial equilibrium, Nonlinear programming, Mathematics
Abstract

Spatial equilibrium problems are frequently formulated as large scale quadratic programming problems or linear complementarity problems. We show that these problems can be reduced to two or more smaller problems with Generalized Benders Decomposition. The procedure then becomes iterative with the repetitive solution of the smaller problems. In practice, the iterative procedure has converged rapidly.

Published
1980
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