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46 results on '"Joshi, Kishore"'

4. Dosimetric Impact of Voluntary Deep Inspiration Breath Hold (DIBH) in Mediastinal Hodgkin Lymphomas: A Comparative Evaluation of Three Different Intensity Modulated Radiation Therapy (IMRT) Delivery Methods Using Voluntary DIBH and Free Breathing Techniques

Author

Mohanty, Samarpita, primary, Patil, Divya, additional, Joshi, Kishore, additional, Gamre, Poonam, additional, Mishra, Ajay, additional, Khairnar, Sunil, additional, Kakoti, Sangeeta, additional, Nayak, Lingaraj, additional, Punatar, Sachin, additional, Jain, Jeevanshu, additional, Phurailatpam, Reena, additional, and Goda, Jayant S., additional

Published
2024
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10. Development and validation of single-optimization knowledge-based volumetric modulated arc therapy model plan in nasopharyngeal carcinomas

Author

Sinha, Shwetabh, primary, Kumar, Anuj, additional, Maheshwari, Guncha, additional, Mohanty, Samarpita, additional, Joshi, Kishore, additional, Shinde, Prakash, additional, Gupta, Deeksha, additional, Kale, Shrikant, additional, Phurailatpam, Reena, additional, Swain, Monali, additional, Budrukkar, Ashwini, additional, Kinhikar, Rajesh, additional, and Ghosh-Laskar, Sarbani, additional

Published
2023
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11. Imaging-Based Patterns of Failure following Re-Irradiation for Recurrent/Progressive High-Grade Glioma

Author

Datta, Debanjali, primary, Dasgupta, Archya, additional, Chatterjee, Abhishek, additional, Sahu, Arpita, additional, Bhattacharya, Kajari, additional, Meena, Lilawati, additional, Joshi, Kishore, additional, Puranik, Ameya, additional, Dev, Indraja, additional, Moiyadi, Aliasgar, additional, Shetty, Prakash, additional, Singh, Vikas, additional, Patil, Vijay, additional, Menon, Nandini, additional, Sridhar, Sridhar, additional, Sahay, Ayushi, additional, and Gupta, Tejpal, additional

Published
2023
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12. Can knowledge based treatment planning of VMAT for post-mastectomy locoregional radiotherapy involving internal mammary chain and supraclavicular fossa improve performance efficiency?

Author

Phurailatpam, Reena, primary, Sah, Muktar kumar, additional, Wadasadawala, Tabassum, additional, Khan, Asfiya, additional, Palottukandy, Jithin, additional, Gayake, Umesh, additional, Jain, Jeevanshu, additional, Sarin, Rajiv, additional, Pathak, Rima, additional, Krishnamurthy, Revathy, additional, Joshi, Kishore, additional, and Swamidas, Jamema, additional

Published
2023
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13. Diagnostic Performance of Response Assessment FDG‐PET/CECT in HNSCC Treated With Definitive Radio(chemo)therapy Using NI‐RADS.

Author

Paul, Sonz, Gupta, Tejpal, Purandare, Nilendu, Joshi, Kishore, Ghosh‐Laskar, Sarbani, Budrukkar, Ashwini, Swain, Monali, Sinha, Shwetabh, Kumar, Anuj, Joshi, Amit, Prabhash, Kumar, Nair, Sudhir, Rangarajan, Venkatesh, and Agarwal, Jai Prakash

Abstract

Objective: To assess the diagnostic performance of response assessment 18F‐fluorodeoxyglucose positron emission tomography/contrast‐enhanced computed tomography (FDG‐PET/CECT) following definitive radio(chemo)therapy in head and neck squamous cell carcinoma (HNSCC) using Neck Imaging Reporting and Data System (NI‐RADS). Study Design: A retrospective analysis from a prospectively maintained dataset. Setting: Tertiary‐care comprehensive cancer center in a low‐middle‐income country. Methods: Adults with newly diagnosed, biopsy‐proven, nonmetastatic HNSCC treated with definitive radio(chemo)therapy were included. Posttreatment response assessment FDG‐PET/CECT scans were retrospectively assigned NI‐RADS categories (1‐3) for the primary site, neck, and both sites combined. Locoregional recurrence occurring within 2‐years was defined as the event of interest. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall accuracy were calculated. Locoregional control stratified by NI‐RADS categories was computed with the Kaplan‐Meier method and compared using the log‐rank test. Results: Posttreatment FDG‐PET/CECT scans were available in 190 patients constituting the present study cohort. Sensitivity, specificity, PPV, NPV, and overall accuracy of the NI‐RADS template for the primary site was 73.5%, 81.4%, 46.3%, 93.4%, and 80.0%, respectively. Similar metrics for the neck were 72.7%, 87.5%, 43.2%, 96.1%, and 85.8%, respectively. Combining primary site and neck, the corresponding metrics of diagnostic accuracy were 84.4%, 69.7%, 46.3%, 93.5%, and 73.2%, respectively. At a median follow‐up of 40 months, Kaplan‐Meier estimates of 2‐year locoregional control were significantly higher for NI‐RADS category 1 (94.2%) compared to NI‐RADS category 2 (69.4%) and category 3 (20.4%), respectively (stratified log‐rank p <.0001). Conclusion: FDG‐PET/CECT using the NI‐RADS template is associated with good diagnostic performance and prognostic utility in HNSCC treated with definitive radio(chemo)therapy. [ABSTRACT FROM AUTHOR]

Published
2023
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14. Impact of in-homogenity corrected dose calculation of clinical Brachytherapy sites

Author

Jamema, S V, Paul, Siji N, Devi, Reena, Joshi, Kishore, Budrukkar, Ashwini, Laskar, S, Laskar, S G, Mahantshetty, Umesh, Sawant, Mayur, Moundekar, Pooja, Deshpande, D D, MAGJAREVIC, Ratko, Editor-in-chief, Ladyzynsk, Piotr, Series editor, Ibrahim, Fatimah, Series editor, Lacković, Igor, Series editor, Rock, Emilio Sacristan, Series editor, and Jaffray, David A., editor

Published
2015
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16. Image-guidance triggered adaptive radiation therapy in head and neck squamous cell carcinoma: single-institution experience and implications for clinical practice

Author

Gupta, Tejpal, primary, Maheshwari, Guncha, additional, Joshi, Kishore, additional, Sawant, Priya, additional, Mishra, Ajay, additional, Khairnar, Sunil, additional, Patel, Prapti, additional, Sinha, Shwetabh, additional, Swain, Monali, additional, Budrukkar, Ashwini, additional, Ghosh-Laskar, Sarbani, additional, and Agarwal, Jai-Prakash, additional

Published
2022
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17. RADT-26. PATTERNS OF RECURRENCE IN PATIENTS TREATED WITH RE-IRRADIATION FOR RECURRENT HIGH-GRADE GLIOMA

Author

Datta, Debanjali, primary, Dasgupta, Archya, additional, Meena, Lilawati, additional, Chatterjee, Abhishek, additional, Sahu, Arpita, additional, Chaudhari, Amit, additional, Joshi, Kishore, additional, Puranik, Ameya, additional, Rangarajan, Venkatesh, additional, Singh, Vikas, additional, Shetty, Prakash, additional, Moiyadi, Aliasgar, additional, Menon, Nandini, additional, Patil, Vijay, additional, Sahay, Ayushi, additional, Sridhar, Epari, additional, Kinhikar, Rajesh, additional, and Gupta, Tejpal, additional

Published
2022
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18. CLRM-12 TITLE: STEREOTACTIC RADIOSURGERY (ADJUVANT OR NEOADJUVANT) COMPARED TO HIPPOCAMPAL AVOIDANCE WHOLE BRAIN RADIATION THERAPY WITH SIMULTANEOUS INTEGRATED BOOST FOR LIMITED BRAIN METASTASES (SRS-CHART): PHASE III OPEN-LABEL PARALLEL-GROUP RANDOMIZED CONTROLLED TRIAL

Author

Dasgupta, Archya, primary, Selvarajan, Jeevi, additional, Chatterjee, Abhishek, additional, Moiyadi, Aliasgar, additional, Shetty, Prakash, additional, Singh, Vikas, additional, Sahu, Arpita, additional, Bhattacharya, Kajari, additional, Sridhar, Epari, additional, Sahay, Ayushi, additional, Shah, Aekta, additional, Joshi, Kishore, additional, Kinhikar, Rajesh, additional, Kannan, Sadhana, additional, and Gupta, Tejpal, additional

Published
2022
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19. Implementation of a visual feedback system for motion management during radiation therapy

Author

Swamidas, Jamema, Rose, John, Chopra, Supriya, Paul, Siji, Joshi, Kishore, Panda, Subhajit, Ph, Reena, and Agarwal, Jai

Subjects
Human mechanics -- Control, Cancer -- Care and treatment, Radiotherapy -- Management, Imaging systems -- Usage, Feedback loops (Systems theory) -- Usage, Imaging technology, Company business management, Health
Abstract

Byline: Jamema. Swamidas, John. Rose, Supriya. Chopra, Siji. Paul, Kishore. Joshi, Subhajit. Panda, Reena. Ph, Jai. Agarwal Purpose: To describe the details of an in-house video goggles feedback system assembled [...]

Published
2021

20. Computerized tomography‑based first order tumor texture features in non‑small cell lung carcinoma treated with concurrent chemoradiation: A simplistic and potential surrogate imaging marker for survival.

Author

Nayak, Prashant, Sinha, Shwetabh, Goda, Jayant S., Sahu, Arpita, Joshi, Kishore, Choudhary, Oindrilla Roy, Mhatre, Ritesh, Mummudi, Naveen, and Agarwal, Jai Prakash

Subjects
BIOMARKERS, PROPORTIONAL hazards models, PROGNOSIS, COMPUTED tomography, CHEMORADIOTHERAPY
Abstract

Objectives: This study examines the role of tumor texture on computed tomography(CT) images as a complement to clinical prognostic factors in predicting survival in patients of non‑small cell lung carcinoma (NSCLC) treated with radical chemo‑radiation (CRT). Methods: A total of 93 patients with confirmed NSCLC treated with CRT accrued in a study approved by the institutional ethics committee were analyzed for CT‑based radiomic features. Pretreatment CT images were used to contour the primary tumor and texture features were computed by the image filtration method to differentially highlight fine to coarse textures. Texture parameters included mean intensity, entropy, kurtosis, standard deviation, and mean positive pixel and skewness. Optimal threshold cut‑off values of the above tumor texture features were analyzed. These features were explored as imaging biomarkers to predict survival using Kaplan–Meier and Cox proportional hazard model. Results: Median follow‑up of the entire cohort was 23.5 months [Interquartile range, IQR: 14–37] while for alive patients, median follow‑up was 31 months (IQR: 23–49), 47 (50.6%) patients had died at the last follow‑up. Univariate analysis revealed certain features like age, gender, response to therapy, and texture features like mean and kurtosis in CT images to be significant predictors of survival. In multivariate analysis, age (P = 0.006), gender (P = 0.004), treatment response (P < 0.0001), and two CT texture parameters: mean (P = 0.027) and kurtosis (P = 0.002) were independent prognostic factors of survival. Interpretation and Conclusion: CT‑derived tumor heterogeneity (mean and kurtosis) complements clinical factors for predicting survival in NSCLC patients treated with CRT. Tumor radiomics warrants further validation as potential prognostic biomarkers for these patients. [ABSTRACT FROM AUTHOR]

Published
2023
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22. Computerized tomography-based first order tumor texture features in non-small cell lung carcinoma treated with concurrent chemoradiation: A simplistic and potential surrogate imaging marker for survival

Author

Goda, JayantS, primary, Nayak, Prashant, additional, Sinha, Shwetabh, additional, Sahu, Arpita, additional, Joshi, Kishore, additional, Choudhary, OindrillaRoy, additional, Mhatre, Ritesh, additional, Mummudi, Naveen, additional, and Agarwal, JaiPrakash, additional

Published
2022
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27. Higher Education in India: Issues related to Access, Equity, Efficiency, Quality and Internationalization

Author

Joshi, Kishore M. and Ahir, Kinjal V.

Subjects
Higher education, India, access, equity, efficiency, quality, internationalization
Abstract

The Indian higher education system is the largest in the world in terms of the number of institutions and the second largest in enrolments. Access to higher education in India has grown tremendously in context of the number of institutions and enrolments. However, the Gross Enrolment Ratio (GER) is still much lower. Higher education in India faces six types of challenges related to equity each associated with gender, caste, interstate, religion, spatial, and income. In terms of efficiency while rates of returns were higher for higher education levels as compared to the lower levels of education in India, however, the problem of appropriate employment amongst higher education graduates still persists. Despite consistent efforts in enhancing the quality of higher education in India, effective measures are required to make it internationally competitive. Indian higher education will have to address equity, quality and efficiency issues in a pragmatic manner through effective policy framework to become globally competitive and relevant to the labour market demand., Academia, No 14 (2019)

Published
2019
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28. Stereotactic body radio therapy for inoperable large hepatocellular cancers: results from a clinical audit

Author

Chopra, Supriya, primary, George, Karishma, additional, Engineer, Reena, additional, Rajamanickam, Karthick, additional, Nojin, Siji, additional, Joshi, Kishore, additional, Swamidas, Jamema, additional, Shetty, Nitin, additional, Patkar, Shraddha, additional, Patil, Prachi, additional, Ostwal, Vikas, additional, Mehta, Shaesta, additional, and Goel, Mahesh, additional

Published
2019
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33. Protocol for a phase III randomized trial of chemoradiation and systemic chemotherapy vs. systemic chemotherapy alone in patients with unresectable nonmetastatic cholangiocarcinoma

Author

Chopra, Supriya, primary, Engineer, Reena, additional, Mathew, Ashwathy Susan, additional, Mehta, Shaesta, additional, Ostwal, Vikas, additional, Goel, Mahesh, additional, Rajamanickam, Karthick, additional, Patil, Prachi, additional, Gupta, Sudeep, additional, Shetty, Nitin, additional, Kannan, Sadhana, additional, Polnaya, Ashwin, additional, Patkar, Shraddha, additional, Rangarajan, Venkatesh, additional, Agarwal, Archi, additional, Ramadwar, Mukta, additional, Shrikhande, Shailesh, additional, Joshi, Kishore, additional, Dandpani, Epili, additional, and Shrivastava, Shyam Kishore, additional

Published
2017
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34. Protocol for an integrated phase II/III randomised controlled trial of transarterial chemotherapy and sorafenib with or without stereotactic body radiation therapy in patients with nonmetastatic unresectable hepatocellular carcinoma

Author

Chopra, Supriya, primary, Shetty, Nitin, additional, Goel, Mahesh, additional, Engineer, Reena, additional, Rajamanickam, Karthick, additional, Kulkarni, Suyash, additional, Polnaya, Ashwin, additional, Patkar, Shradha, additional, Ostwal, Vikas, additional, Ramadwar, Mukta, additional, Swamidas, Jamema, additional, Phurailatpam, Reena, additional, Paul, Siji N., additional, Dhandpani, Epili, additional, Joshi, Kishore, additional, Kannan, Sadhana, additional, Rangarajan, Venkatesh, additional, Mehta, Shaesta, additional, Patil, Prachi, additional, and Shrivastava, S. K., additional

Published
2017
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35. Sebis Double (H)Edged Sword On ODI Subscribers And Issuers

Author

Joshi, Kishore

Subjects
Hedging (Finance) -- Economic aspects -- Forecasts and trends, Derivatives (Financial instruments) -- Economic aspects -- Forecasts and trends, Market trend/market analysis, Business, international
Abstract

SEBI restricts the use of the ODI route, disallowing ODI issuance on derivatives unless held for hedging purposes; Purpose seems two-fold - (i) curbing speculative trading in derivatives through the [...]

Published
2017

45. Sts1 Plays a Key Role in Targeting Proteasomes to the Nucleus.

Author

Li Chen, Romero, Lizbeth, Show-Mei Chuang, Tournier, Vincent, Joshi, Kishore Kumar, Jung Ah Lee, Kovvali, Gopala, and Madura, Kiran

Subjects
*CELL nuclei, *NUCLEAR proteins, *GENETIC mutation, *BIOMOLECULES, *CELL adhesion molecules
Abstract

The evidence that nuclear proteins can be degraded by cytosolic proteasomes has received considerable experimental support. However, the presence of proteasome subunits in the nucleus also suggests that protein degradation could occur within this organelle. We determined that Sts1 can target proteasomes to the nucleus and facilitate the degradation of a nuclear protein. Specific sts1 mutants showed reduced nuclear proteasomes at the nonpermissive temperature. In contrast, high expression of Sts1 increased the levels of nuclear proteasomes. Sts1 targets proteasomes to the nucleus by interacting with Srp1, a nuclear import factor that binds nuclear localization signals. Deletion of the NLS in Sts1 prevented its interaction with Srp1 and caused proteasome mislocalization. In agreement with this observation, a mutation in Srp1 that weakened its interaction with Sts1 also reduced nuclear targeting of proteasomes. We reported that Sts1 could suppress growth and proteolytic defects of rad23Δ rpn10Δ. We show here that Sts1 suppresses a previously undetected proteasome localization defect in this mutant. Taken together, these findings explain the suppression of rad23Δ rpn10Δ by Sts1 and suggest that the degradation of nuclear substrates requires efficient proteasome localization. [ABSTRACT FROM AUTHOR]

Published
2011
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46. Higher education in Germany

Author

Michel-Schertges, Dirk, Schertges, Claudia, Joshi, Kishore M., and Paivandi, Saeed

Subjects
Videregående uddannelse, Internationale komparative undersøgelser
Published
2014

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