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1. An evaluation of the effect of an educational intervention for Australian social workers on competence in delivering brief cognitive behavioural strategies: A randomised controlled trial

Author

Moulding R, Bland R, Joubert L, Blashki G, Armstrong G, Gunn J, and Naccarella L

Subjects
Public aspects of medicine, RA1-1270
Abstract

Abstract Background Broad community access to high quality evidence-based primary mental health care is an ongoing challenge around the world. In Australia one approach has been to broaden access to care by funding psychologists and other allied health care professionals to deliver brief psychological treatments to general practitioners' patients. To date, there has been a scarcity of studies assessing the efficacy of social worker delivered psychological strategies. This study aims to build the evidence base by evaluating the impact of a brief educational intervention on social workers' competence in delivering cognitive behavioural strategies (strategies derived from cognitive behavioural therapy). Methods A randomised controlled trial design was undertaken with baseline and one-week follow-up measurement of both objective and self-perceived competence. Simulated consultations with standardised depressed patients were recorded on videotape and objective competence was assessed by blinded reviewers using the Cognitive Therapy Scale. Questionnaires completed by participants were used to measure self-perceived competence. The training intervention was a 15 hour face-to-face course involving presentations, video example consultations, written materials and rehearsal of skills in pairs. Results 40 Melbourne-based (Australia) social workers enrolled and were randomised and 9 of these withdrew from the study before the pre training simulated consultation. 30 of the remaining 31 social workers (97%) completed all phases of the intervention and evaluation protocol (16 from intervention and 14 from control group). The intervention group showed significantly greater improvements than the control group in objective competence (mean improvement of 14.2 (7.38-21.02) on the 66 point Cognitive Therapy Scale) and in subjective confidence (mean improvement of 1.28 (0.84-1.72) on a 5 point Likert scale). On average, the intervention group improved from below to above the base competency threshold on the Cognitive Therapy Scale whilst the control group remained below. Conclusions Social workers can attain significant improvements in competency in delivering cognitive behavioural strategies from undertaking brief face to face training. This is relevant in the context of health reforms that involve social worker delivery of evidence based psychological care. Further research is required to assess how these improvements in competence translate into performance in practice and clinical outcomes for patients.

Published
2010
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3. Impact of the mutational load on the virological response to a first-line rilpivirine-based regimen.

Author

Dimeglio, Chloé, Raymond, Stéphanie, Nicot, Florence, Jeanne, Nicolas, Carcenac, Romain, Lefebvre, Caroline, Izopet, Jacques, Roussel, C, Guillou-Guillemette, H Le, Alloui, C, Bettinger, D, Pallier, C, Fleury, H, Bellecave, P, Recordon-Pinson, P, Payan, C, Vallet, S, Vabret, A, Dina, J, Henquell, C, Mirand, A, Bouvier-Alias, M, de Rougemont, A, Si-Mohammed, A, Santos, G Dos, Morand, P, Signori-Schmuck, A, Bocket, L, Rogez, S, Andre, P, Tardy, JC, Trabaud, MA, Tamalet, C, Delamare, C, Montes, B, Schvoerer, E, Jeulin, H, Ferré, V, Rodallec, A, Guen, L Le, Cottalorda, J, Guinard, J, Guiguon, A, Descamps, D, Charpentier, C, Visseaux, B, Peytavin, G, Krivine, A, Bouviers-Alias, M, Avettand-Fenoel, V, Marcelin, AG, Calvez, V, Soulié, C, Wirden, M, Morand-Joubert, L, Lambert-Niclot, S, Fofana, D, Delaugerre, C, Chaix, ML, Mahjoub, N, Amiel, C, Schneider, V, Giraudeau, G, Beby-Defaux, A, Brodard, V, Maillard, A, Plantier, JC, Mourez, T, Leoz, M, Chaplain, C, Bourlet, T, Fafi-Kremer, S, Stoll-Keller, F, Schmitt, MP, Barth, H, Yerly, S, Poggi, C, Izopet, J, Raymond, S, Barin, F, Chaillon, A, Marque-Juillet, S, Roque-Afonso, AM, Haïm-Boukobza, S, Flandre, P, Grudé, M, Assoumou, L, and Costagliola, D

Subjects
Clinical Research, Genetics, HIV/AIDS, Infectious Diseases, Infection, Antiretroviral Therapy, Highly Active, Drug Resistance, Viral, Female, Genome, Viral, Genotype, HIV Infections, HIV-1, High-Throughput Nucleotide Sequencing, Humans, Male, Mutation, Rilpivirine, Treatment Outcome, Viral Load, French National Agency for Research on AIDS and Viral Hepatitis (ANRS) AC11 Resistance Study Group, Microbiology, Medical Microbiology, Pharmacology and Pharmaceutical Sciences
Abstract

ObjectivesTo determine how the load of rilpivirine-resistant variants (mutational load) influences the virological response (VR) of HIV-1-infected patients to a rilpivirine-based first-line regimen.Patients and methodsFour hundred and eighty-nine patients infected with HIV-1 whose reverse transcriptase gene had been successfully resistance genotyped using next-generation sequencing were given a first-line regimen containing rilpivirine. Variables associated with the VR at 12 months were identified using a logistic model. The results were used to build a multivariate model for each mutational load threshold and the R2 variations were analysed to identify the mutational load threshold that best predicted the VR.ResultsThe mutational load at baseline was the only variable linked to the VR at 12 months (P  1700 copies/mL and to 50% when the mutational load was > 9000 copies/mL. The threshold of 9000 copies/mL was associated with the VR at 12 months with an OR of 36.7 (95% CI 4.7-285.1). The threshold of 1700 copies/mL was associated with the VR at 12 months with an OR of 7.2 (95% CI 1.4-36.8).ConclusionsThere is quantifiable evidence that determining a mutational load threshold can be used to identify those patients on a first-line regimen containing rilpivirine who are at risk of virological failure. The clinical management of HIV-infected patients can be improved by evaluating the frequency of mutant variants at a threshold of

Published
2019

4. Impact of Human Immunodeficiency Virus Type 1 Minority Variants on the Virus Response to a Rilpivirine-Based First-line Regimen

Author

Raymond, Stéphanie, Nicot, Florence, Pallier, Coralie, Bellecave, Pantxika, Maillard, Anne, Trabaud, Mary Anne, Morand-Joubert, Laurence, Rodallec, Audrey, Amiel, Corinne, Mourez, Thomas, Bocket, Laurence, Beby-Defaux, Agnès, Bouvier-Alias, Magali, Lambert-Niclot, Sidonie, Charpentier, Charlotte, Malve, Brice, Mirand, Audrey, Dina, Julia, Le Guillou-Guillemette, Hélène, Marque-Juillet, Stéphanie, Signori-Schmuck, Anne, Barin, Francis, Si-Mohamed, Ali, Fenoel, Véronique Avettand, Roussel, Catherine, Calvez, Vincent, Saune, Karine, Marcelin, Anne Geneviève, Rodriguez, Christophe, Descamps, Diane, Izopet, Jacques, Lagier, E, Roussel, C, Le Guillou-Guillemette, H, Alloui, C, Bettinger, D, Pallier, C, Fleury, H, Reigadas, S, Bellecave, P, Recordon-Pinson, P, Payan, C, Vallet, S, Vabret, A, Dina, J, Henquell, C, Mirand, A, Bouvier-Alias, M, de Rougemont, A, Dos Santos, G, Morand, P, Signori-Schmuck, A, Bocket, L, Rogez, S, Andre, P, Tardy, JC, Trabaud, MA, Tamalet, C, Delamare, C, Montes, B, Schvoerer, E, Ferré, V, André-Garnier, E, Cottalorda, J, Guinard, J, Guiguon, A, Descamps, D, Brun-Vézinet, F, Charpentier, C, Visseaux, B, Peytavin, G, Krivine, A, Si-Mohamed, A, Avettand-Fenoel, V, Marcelin, AG, Calvez, V, Lambert-Niclot, S, Soulié, C, Wirden, M, Morand-Joubert, L, Delaugerre, C, Chaix, ML, Amiel, C, Schneider, V, Giraudeau, G, Defaux, A Beby-, Brodard, V, Maillard, A, Plantier, JC, Chaplain, C, Bourlet, T, Fafi-Kremer, S, Stoll-Keller, F, Schmitt, MP, Barth, H, Yerly, S, Poggi, C, Izopet, J, Raymond, S, and Barin, F

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, Immunology, Sexually Transmitted Infections, Clinical Research, Infectious Diseases, Genetics, Minority Health, Antimicrobial Resistance, HIV/AIDS, 2.1 Biological and endogenous factors, Infection, Good Health and Well Being, Adult, Drug Resistance, Viral, Female, Genetic Variation, HIV Infections, HIV-1, Humans, Male, Mutation, Rilpivirine, Viral Load, minority resistant variants, rilpivirine, first-line antiretroviral therapy, ultra-deep sequencing, French National Agency for Research on AIDS and Viral Hepatitis (ANRS) AC11 Resistance Study Group, Biological Sciences, Medical and Health Sciences, Microbiology, Clinical sciences
Abstract

BackgroundMinority resistant variants of human immunodeficiency virus type 1 (HIV-1) could influence the virological response to treatment based on nonnucleoside reverse transcriptase inhibitors (NNRTIs). Data on minority rilpivirine-resistant variants are scarce. This study used next-generation sequencing (NGS) to identify patients harboring minority resistant variants to nucleos(t)ide reverse transcriptase inhibitors and NNRTIs and to assess their influence on the virological response (VR).MethodsAll the subjects, 541 HIV-1-infected patients started a first-line regimen containing rilpivirine. VR was defined as a HIV-1 RNA load 20% in 29% of samples. We identified 43 (8.8%) and 36 (7.4%) patients who harbored rilpivirine-resistant variants with a 1% sensitivity threshold according to the French National Agency for Research on AIDS and Viral Hepatitis and Stanford algorithms, respectively. The VR was 96.9% at month 12. Detection of minority rilpivirine resistant variants was not associated with virological failure (VF). Multivariate analysis indicated that VF at month 12 was associated with a CD4 count

Published
2018

8. Cross-resistance to elvitegravir and dolutegravir in 502 patients failing on raltegravir: a French national study of raltegravir-experienced HIV-1-infected patients

Author

Fourati, Slim, Charpentier, Charlotte, Amiel, Corinne, Morand-Joubert, Laurence, Reigadas, Sandrine, Trabaud, Mary-Anne, Delaugerre, Constance, Nicot, Florence, Rodallec, Audrey, Maillard, Anne, Mirand, Audrey, Jeulin, Hélène, Montès, Brigitte, Barin, Francis, Bettinger, Dominique, Le Guillou-Guillemette, Hélène, Vallet, Sophie, Signori-Schmuck, Anne, Descamps, Diane, Calvez, Vincent, Flandre, Philippe, Marcelin, Anne-Genevieve, Lagier, E, Roussel, C, Le Guillou, H, Alloui, C, Bettinger, D, Pallier, C, Fleury, H, Reigadas, S, Bellecave, P, Recordon-Pinson, P, Payan, C, Vallet, S, Vabret, A, Henquell, C, Mirand, A, Bouvier-Alias, M, de Rougemont, A, Dos Santos, G, Morand, P, Signori-Schmuck, A, Bocket, L, Rogez, S, Andre, P, Tardy, JC, Trabaud, MA, Tamalet, C, Delamare, C, Montes, B, Schvoerer, E, Ferre, V, André-Garnier, E, Cottalorda, J, Guinard, J, Guiguon, A, Descamps, D, Brun-Vézinet, F, Charpentier, C, Visseaux, B, Peytavin, G, Krivine, A, Si-Mohamed, A, Avettand-Fenoel, V, Marcelin, AG, Calvez, V, Lambert-Niclot, S, Soulié, C, Wirden, M, Morand-Joubert, L, Delaugerre, C, Chaix, ML, Amiel, C, Schneider, V, Giraudeau, G, Brodard, V, Maillard, A, Plantier, JC, Chaplain, C, Bourlet, T, Fafi-Kremer, S, Stoll-Keller, F, Schmitt, MP, Barth, H, Yerly, S, Poggi, C, Izopet, J, Raymond, S, Barin, F, Chaillon, A, Marque-Juillet, S, Roque-Afonso, AM, Haïm-Boukobza, S, Flandre, P, Grudé, M, Assoumou, L, Costagliola, D, Allegre, T, Schmit, JL, and Chennebault, JM

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Infectious Diseases, Genetics, Aetiology, 2.1 Biological and endogenous factors, Infection, Adult, Anti-HIV Agents, Drug Resistance, Viral, Female, France, HIV Infections, HIV Integrase, HIV Protease, HIV Reverse Transcriptase, HIV-1, Heterocyclic Compounds, 3-Ring, Humans, Male, Middle Aged, Mutant Proteins, Oxazines, Piperazines, Pyridones, Quinolones, Raltegravir Potassium, Sequence Analysis, DNA, integrase, inhibitors, mutations, patterns, ANRS AC11 Resistance Study Group, Microbiology, Pharmacology and Pharmaceutical Sciences, Clinical sciences, Pharmacology and pharmaceutical sciences
Abstract

ObjectivesThe objectives of this study were to determine the prevalence and patterns of resistance to integrase strand transfer inhibitors (INSTIs) in patients experiencing virological failure on raltegravir-based ART and the impact on susceptibility to INSTIs (raltegravir, elvitegravir and dolutegravir).Patients and methodsData were collected from 502 treatment-experienced patients failing a raltegravir-containing regimen in a multicentre study. Reverse transcriptase, protease and integrase were sequenced at failure for each patient. INSTI resistance-associated mutations investigated were those included in the last ANRS genotypic algorithm (v23).ResultsAmong the 502 patients, at failure, median baseline HIV-1 RNA (viral load) was 2.9 log10 copies/mL. Patients had been previously exposed to a median of five NRTIs, one NNRTI and three PIs. Seventy-one percent harboured HIV-1 subtype B and the most frequent non-B subtype was CRF02_AG (13.3%). The most frequent mutations observed were N155H/S (19.1%), Q148G/H/K/R (15.4%) and Y143C/G/H/R/S (6.7%). At failure, viruses were considered as fully susceptible to all INSTIs in 61.0% of cases, whilst 38.6% were considered as resistant to raltegravir, 34.9% to elvitegravir and 13.9% to dolutegravir. In the case of resistance to raltegravir, viruses were considered as susceptible to elvitegravir in 11% and to dolutegravir in 64% of cases. High HIV-1 viral load at failure (P

Published
2015

9. Antiretroviral-naive and -treated HIV-1 patients can harbour more resistant viruses in CSF than in plasma

Author

Soulie, C, Descamps, D, Grude, M, Schneider, V, Trabaud, M-A, Morand-Joubert, L, Delaugerre, C, Montes, B, Barin, F, Ferre, V, Raymond, S, Jeulin, H, Alloui, C, Yerly, S, Pallier, C, Reigadas, S, Signori-Schmuck, A, Guigon, A, Fafi-Kremer, S, Haim-Boukobza, S, Mirand, A, Maillard, A, Vallet, S, Roussel, C, Assoumou, L, Calvez, V, Flandre, P, Marcelin, A-G, Lagier, E, Le Guillou, H, Bettinger, D, Fleury, H, Bellecave, P, Recordon-Pinson, P, Payan, C, Vabret, A, Henquell, C, Bouvier-Alias, M, de Rougemont, A, Dos Santos, G, Morand, P, Bocket, L, Rogez, S, Andre, P, Tardy, JC, Trabaud, MA, Tamalet, C, Delamare, C, Schvoerer, E, Andre-Garnier, E, Cottalorda, J, Guinard, J, Guiguon, A, Brun-Vezinet, F, Charpentier, C, Visseaux, B, Peytavin, G, Krivine, A, Si-Mohamed, A, Avettand-Fenoel, V, Marcelin, AG, Lambert-Niclot, S, Wirden, M, Chaix, ML, Amiel, C, Giraudeau, G, Brodard, V, Plantier, JC, Chaplain, C, Bourlet, T, Stoll-Keller, F, Schmitt, MP, Barth, H, Poggi, C, Izopet, J, Chaillon, A, Marque-Juillet, S, and Roque-Afonso, AM

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, HIV/AIDS, Infectious Diseases, Antimicrobial Resistance, Genetics, Clinical Research, Neurosciences, Infection, Adult, Anti-HIV Agents, Antiretroviral Therapy, Highly Active, Drug Resistance, Viral, Female, Genotype, HIV Infections, HIV-1, Humans, Male, Microbial Sensitivity Tests, Middle Aged, Mutation, Nervous System Diseases, Viral Load, ANRS Resistance AC11 Group, ARV, CSF, HIV, resistance, Microbiology, Pharmacology and Pharmaceutical Sciences, Clinical sciences, Pharmacology and pharmaceutical sciences
Abstract

OBJECTIVES: The neurological disorders in HIV-1-infected patients remain prevalent. The HIV-1 resistance in plasma and CSF was compared in patients with neurological disorders in a multicentre study. METHODS: Blood and CSF samples were collected at time of neurological disorders for 244 patients. The viral loads were >50 copies/mL in both compartments and bulk genotypic tests were realized. RESULTS: On 244 patients, 89 and 155 were antiretroviral (ARV) naive and ARV treated, respectively. In ARV-naive patients, detection of mutations in CSF and not in plasma were reported for the reverse transcriptase (RT) gene in 2/89 patients (2.2%) and for the protease gene in 1/89 patients (1.1%). In ARV-treated patients, 19/152 (12.5%) patients had HIV-1 mutations only in the CSF for the RT gene and 30/151 (19.8%) for the protease gene. Two mutations appeared statistically more prevalent in the CSF than in plasma: M41L (P=0.0455) and T215Y (P=0.0455). CONCLUSIONS: In most cases, resistance mutations were present and similar in both studied compartments. However, in 3.4% of ARV-naive and 8.8% of ARV-treated patients, the virus was more resistant in CSF than in plasma. These results support the need for genotypic resistance testing when lumbar puncture is performed.

Published
2015

10. EE485 Cost-Effectiveness of a 4 Days-a-Week Triple Therapy in Persons Living with HIV: An Ancillary Study of the Anrs 170 Quatuor Noninferiority Trial

Author

Hejblum, G., primary, Daher, S., additional, Moulaire, P., additional, Amat, K.A., additional, Lambert-Niclot, S., additional, Allavena, C., additional, Katlama, C., additional, Lacombe, K., additional, Ponscarme, D., additional, Ghosn, J., additional, Gibowski, S., additional, Alvarez, J.C., additional, Capeau, J., additional, Morand-Joubert, L., additional, Costagliola, D., additional, De Truchis, P., additional, Landman, R., additional, and Assoumou, L., additional

Published
2023
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16. Vulnerabilities and life stressors of people presented to emergency departments with deliberate self-harm; consolidating the experiences to develop a continuum of care using a mixed-method framework

Author

Devassy, SM, Scaria, L, Varghese, J, Benny, AM, Hill, N, Joubert, L, Devassy, SM, Scaria, L, Varghese, J, Benny, AM, Hill, N, and Joubert, L

Abstract

OBJECTIVE: Suicide is a crucial public health concern. However, the interactions between bio psychosocial vulnerabilities and stressors leading to deliberate self-harm behavior remain unexplored, especially in the Indian context. This study examined the experiences leading to self-harm behavior among people who presented to emergency departments with suicidal attempts. METHODS: In this mixed-methods study, we enrolled 44 patients who presented with self-harm behavior at three tertiary health care facilities between October and December 2019. To collect quantitative data, we employed standardized tools: General Health Questionnaire (GHQ-28), General Help-Seeking Questionnaire, Mini International Neuropsychiatric Interview, and the Brief Resilience Scale. Further, we conducted semi-structured interviews to qualitatively explore participants' life experiences and other risk factors. Qualitative analyses were performed using thematic analysis and quantitative descriptive and inferential statistics were performed using STATA software. RESULTS: The mean age of subjects were 29.8 years. The mean suicidality score for the patients was 26 (±8.7). In univariate analysis, depression and anxiety were positively associated with suicidality. While help-seeking behavior and resilience were negatively associated with suicidality. Qualitative results were centered on three major themes; life stressors, family related stressors, and social support-related vulnerabilities. The subjects' lived experiences were introduced in the backdrop of the interplay of vulnerabilities and stressors. CONCLUSION: The biopsychosocial vulnerabilities remain dormant until it is activated by life stressors resulting in severe self-harm behaviors. Mental health team-driven assertive engagement, positive coping, and social support interventions would help prevent reattempts in people with self-harm behaviors.

Published
2023

21. Prevalence of baseline virological risk factors of increased virological failure to CAB+RPV among ARV-naive patients

Author

Charpentier, C., Storto, A., Soulie, C., Ferre, VM., Wirden, M., Joly, V., Lambert-Niclot, S., Morand-Joubert, L., Landman, R., Lacombe, K., Katlama, C., Ghosn, J., Marcelin, A-G., Calvez, V., and Descamps, D.

Subjects
Drug therapy, Development and progression, Genetic aspects, Patient outcomes, Health aspects, HIV infections -- Genetic aspects -- Development and progression -- Drug therapy, Gene mutation -- Health aspects, Drug resistance -- Genetic aspects, Antiretroviral agents -- Patient outcomes, Genetic polymorphisms -- Health aspects, Gene mutations -- Health aspects, Antiviral agents -- Patient outcomes, HIV infection -- Genetic aspects -- Development and progression -- Drug therapy
Abstract

Background: Multivariable baseline factor analysis across CAB+RPV phase 3 studies recently showed that HIV-1 subtypes A6/A1, characterized by the L74I integrase (IN) polymorphism, and presence of RPV resistance-associated mutations (RAM), [...]

Published
2021
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22. Echocardiographic features of infective endocarditis in South Africa: A prospective cohort study

Author

Alfonso Pecoraro, Herbst P, Joubert L, Hassen K, Pienaar C, Taljaard J, Prozesky H, Janson J, and Doubell A

Subjects
Cohort Studies, South Africa, Endocarditis, Echocardiography, Rheumatic Heart Disease, Humans, Endocarditis, Bacterial, Prospective Studies
Abstract

Background: Historically, infective endocarditis (IE) in South Africa (SA) was associated with the viridans group of streptococci affectingpatients with underlying rheumatic heart disease (RHD). A changing IE bacteriological profile raises the question of whether the profile of underlying valvular abnormality has changed.Objectives: To investigate the prevalence of underlying structural valve abnormalities and their aetiologies associated with IE in SA, and describe the typical imaging findings.Methods: The Tygerberg Endocarditis Cohort study prospectively enrolled patients with IE between November 2019 and April 2021. Patients underwent detailed transthoracic and transoesophageal echocardiography to assess their underlying cardiac and valvular structure.Results: Among 71 patients included, a predisposing endocardial abnormality was detected in 49.3%, with RHD the most common single identifiable aetiology (16.9%). The in-hospital mortality rate was similar in patients with and without a predisposing endocardial abnormality (20% v. 16.7%; p=0.72), as was the rate of embolic events (20% v. 27.2%; p=0.58). Significantly more patients with a predisposing endocardial abnormality had an indication for surgery (94.3% v. 69.4%; p10 mm was associated with an increased risk of in-hospital mortality (24% v. 5%; p=0.05).Conclusion: We observed a marked decrease in the prevalence of RHD in this cohort of patients with IE. The viridans group of streptococci was an uncommon cause of IE in patients with no predisposing endocardial abnormality detected. The presence of a predisposing endocardial abnormality was not associated with an increased risk of in-hospital mortality or embolic events. Linear vegetation length >10 mm was associated with an increased risk of in-hospital mortality in patients with left-sided IE.

Published
2022

24. Lesbianism: Deconstructing the Christian church and social hierarchies in South Africa.

Author

Joubert, L.

Subjects
*SOCIAL hierarchies, *LESBIAN identity, *LESBIANISM, *LESBIAN couples, *LGBTQ+ communities, *HETEROSEXUALITY
Abstract

Christianity's emphasis on faith in Jesus Christ can shape perceptions of LGBTQI individuals. The notion that heterosexuality is the only biblically sanctioned sexual orientation, rooted in patriarchal ideals, presents a religious challenge for the LGBTQI1 community. Lesbian couples and their children often face hostility and exclusion from local religious communities, due to their departure from heterosexual norms. This article employs Michel Foucault's discourse and power theory to examine how the Christian church and society maintain a fixed social hierarchy. It focuses on biblical discourses shaping lesbian identity and highlights how colonial influences have fuelled a homophobic interpretation of the Bible. The argument advocates for a more positive relationship between churches and the LGBTQI community, asserting that the Christian church and social hierarchies negatively impact on lesbian identity through the use of biblical text and patriarchal views. [ABSTRACT FROM AUTHOR]

Published
2023
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26. First cases of Omicron in France are exhibiting mild symptoms, November 2021–January 2022

Author

Andrieu, A., Broustal, O., Chene, S., Chent, S., Fougère, E., Gbaguidi, G., Hamidouche, M., Lamy, A., Mano, Q., Mastrovito, B., Mercier, A., Modenesi, G., Picard, G., Prudhomme, J., Rapilly, F., Riondel, A., Rivière, M., Villegas Ramirez, B., Zhu-Soubise, A., Zurbaran, M., Amzert, A., Andreoletti, L., Bal, A., Beaurepere, R., Behillil, S., Belec, L., Bernard, C., Bocket, L., Bouri, L., Bourlet, T., Bressollette-Bodin, C., Brichler, S., Brugerolles, C., Cado, S., Calvez, V., Capron, N., Castelain, S., Castro-Alvarez, J., Chaix, M.-L., Charpentier, C., Che, D., Chillou, C., Colson, P., Coudene, P., Crinquette, A., De Rougemont, A., Delagrèverie, H., Delamare, C., Denecker-Berardino, T., Descamps, D., Desroches, M., Destras, G., Dos Santos, G., Ducancelle, A., Ducreux, S., Duret, T., Enouf, V., Fafi-Kremer, S., Felici, C., Fourati, S., Fournier, P.-E., Gaudy, C., Germain, H., Giordanengo, V., Gorge, O., Haim-Boukobza, S., Henquell, C., Holstein, A., Houhamdi, L., Izopet, J., Jacomo, V., Jacques, A., Jaffar-Bandjee, M.-C., Jimenez, M., Josset, L., Kemeny, S., Lafon, M.-E., Le Bars, A., Le Corguille, G., Lepiller, Q., Levasseur, A., Leveque, N., Lina, B., Madelaine, C., Malabat, C., Marque-Juillet, S., Martin-Dunavit, T., Mavingui, P., Merens, A., Messak, I., Morand-Joubert, L., Naudot, X., Neybecker, P., Pawlotsky, J.-M., Pilorge, L., Plantier, J.-C., Poggi, C., Pretet, M., Ragot, C., Raoul, H., Rogez, S., Roque-Afonso, A.-M., Roquebert, B., Rousset, D., Rozenberg, F., Sagot, C., Sahnoune, S., Salgado, D., Sand, O., Saudemont, C., Schvoerer, E., Simon-Loriere, E., Stephan, R., Sudour, J., Thibault, V., Tuaillon, E., Vabret, A., Vallee, E., Van Der Werf, S., Van Helden, J., Verdurme, L., Vignola, A., Wilkinson, D., Yazdanpanah, Y., Maisa, A., Spaccaferri, G., Fournier, L., Schaeffer, J., Deniau, J., Rolland, P., and Coignard, B.

Published
2022
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27. ENhAncing Lifestyle Behaviors in EndometriaL CancEr (ENABLE): A Pilot Randomized Controlled Trial

Author

Edbrooke, L, Khaw, P, Freimund, A, Carpenter, D, McNally, O, Joubert, L, Loeliger, J, Traill, A, Gough, K, Mileshkin, L, Denehy, L, Edbrooke, L, Khaw, P, Freimund, A, Carpenter, D, McNally, O, Joubert, L, Loeliger, J, Traill, A, Gough, K, Mileshkin, L, and Denehy, L

Abstract

PURPOSE: Endometrial cancer is associated with the highest comorbid disease burden of any cancer. The aim of this trial was to assess the feasibility and safety of an allied health intervention during adjuvant treatment. METHODS: A mixed-methods pilot randomized (2:1) controlled trial with concealed allocation and assessor-blinding. Eligibility criteria: adjuvant endometrial cancer treatment scheduled, disease stage I-IIIC1, ECOG 0-2 and able to perform unsupervised physical activity (PA). Participants received usual care and 8 sessions of weekly, individualized, lifestyle education (diet and PA) with behavior change and social support (intervention group), delivered predominantly by telehealth, or usual care alone. Feasibility outcomes: recruitment and consent rates, decline reasons, program acceptability, intervention adherence and retention. RESULTS: 22/44 eligible patients (50%, 95%CI: 36%, 64%) were recruited over 10 months (14 intervention, 8 usual care). The recruitment rate was 2.2 patients/month (95%CI: 1.4, 3.3). Patients who declined had too much going on (7/22, 32%) or were not interested (6/22, 27%). Mean (SD) age and BMI were 63.2 years (6.8) and 31.9 kg/m2 (6.7). A majority were FIGO stage I (15/22, 68%) and received vaginal brachytherapy (14/22, 64%). Adherence was high, 11/14 (79%, 95%CI: 52%, 92%) participants attended >70% of scheduled sessions. Retention was 100% (95%CI: 85%, 100%) at 9 weeks, however completion of objective measures was impacted by COVID-19 restrictions. Telehealth and online questionnaires enabled participation. No serious adverse events occurred. CONCLUSION: The intervention was acceptable to participants with high levels of adherence and retention. Trial findings will be used to design a future RCT. TRIAL REGISTRATION: The trial was registered on www.anzctr.org.au (ACTRN12619000631101) 29/04/2019.

Published
2022

28. Do Social Media Impact Young Adult Mental Health and Well-Being? A Qualitative Study

Author

Dodemaide, P, Merolli, M, Hill, N, Joubert, L, Dodemaide, P, Merolli, M, Hill, N, and Joubert, L

Abstract

The Social Work profession recognises the ethical and educational implications of social media usage but remains cautious in embracing the technology in the context of clinical practice. Social media platforms allow their users to share thoughts, opinions, experiences, information, develop online communities and access social and emotional support. Social media-focused research in the mental health context has described the risk of vulnerable populations using social media. However, there is a dearth of research examining the lived experiences of young adult social media users or addressing both the perceived risks and benefits. Social Work clinicians need to understand the experience of clients and be able to respond to questions or challenges that service users using social media experience. Deploying inductive thematic content analysis, this study presents the qualitative findings of an online survey eliciting the experience of young adult social media users. Young adults reported varying perspectives, including preferences for anonymity, how social media is employed and consideration that specific platforms are either helpful or harmful. Results are discussed with consideration given to existing literature. This article contributes to the evidence-base for social work and other disciplines, allowing for a greater phenomenological understanding of young adults’ use of social media.

Published
2022

29. Effects of widespread community use of face masks on communication, participation, and quality of life in Australia during the COVID-19 pandemic

Author

Galvin, KL, Tomlin, D, Joubert, L, Story, L, Galvin, KL, Tomlin, D, Joubert, L, and Story, L

Abstract

The objective was to document the influence of face mask use by other people on communication experiences, participation in activities, and quality of life. Australian adults (n = 665) completed an online survey; 90.8% resided in a state with mandatory mask use outside the home and 44.1% self-reported hearing difficulties. Mask use was reported as negatively affecting communication quality in the community (90.2%) and workplace (91.8%), and with household members (59.1%), including an increased requirement for clarification and repetition, increased difficulty communicating, and decreased understanding. Masks influenced feelings when communicating in the community (74.1%) and workplace (76.7%), and with household members (43.6%), including increased fatigue and frustration, and decreased connection to others. Masks influenced the time spent communicating in the community (68.8%) and workplace (67.9%), and with household members (42.3%), including a decrease in the number of individuals communicated with, and the time spent communicating with each individual. Masks influenced participation in activities in the community (50.9%) and workplace (59.7%), and with household members (41.3%), including reduced participation in health-related activities, shopping, and socialising. Influences on quality of life included reduced physical and mental health, including increased loneliness. Female gender and greater self-reported hearing difficulties were significantly associated with increased influence of mask use. The wide-ranging influences of face mask use have implications for physical health and mental health, including social connectedness, and for employers and the economy. As an important measure for combatting disease spread, the negative impacts of mask use must be considered during policy formulation, and appropriate mitigating measures, such as educational campaigns, enacted.

Published
2022

30. FASE-family and social engagement model for prevention and management of self harm behavior-a study protocol for cluster randomized control trial in India

Author

Devassy, SM, Scaria, L, Benny, AM, Cheguvera, N, Varghese, J, Joubert, L, Devassy, SM, Scaria, L, Benny, AM, Cheguvera, N, Varghese, J, and Joubert, L

Abstract

BACKGROUND: Suicide is a substantial public health concern for countries worldwide. Effective preventive and curative interventions for self-harm behavior (SHB) are imperative for nations with an alarmingly high rate of suicide and self-harm behaviors. The intervention protocol named FASE (Family and Social Engagement) consists of comprehensive assessment, Attachment-Based Family Therapy (ABFT), and community linkages for people presenting with suicide or self-harm in emergency departments of tertiary hospitals. METHODS: This article reports the design and protocol for a cluster randomized control trial for suicide prevention and management. After the developed intervention is pilot tested in a tertiary hospital in Kerala, the intervention will be scaled up to be implemented in various tertiary hospitals in Kerala. Each hospital emergency department will be considered a cluster, and these clusters will be randomized to the intervention group and control group in a 1:1 ratio. The eligible people from the intervention clusters will undergo a baseline assessment, a structured moderate intense intervention with twelve sessions spread across 6 months by the trained social workers supervised by the Mental health team, and a follow-up assessment at the end. Participants will be recruited after obtaining consent and explaining the study. The primary outcome includes suicidality measured by the Depressive Symptom Inventory-Suicidality Subscale (DSI-SS), Depression, Anxiety and Stress Scale (DASS), MOS Social Support Survey, and Brief resilience scale (BRS). DISCUSSION: Knowledge generated from this trial can significantly affect new programmatic policy and clinical guidelines that will improve the reduction of suicide rates in the country. TRIAL REGISTRATION: Prospectively registered in Clinical Trial Registry India (ICMR-NIMS) on 18/10/2021 (ref number- REF/2021/10/048264).

Published
2022

31. Risks and Barriers in Substitute Care for the Children of Parents with Serious Mental Illness: A Mixed-Method Study in Kerala, India

Author

Devassy, SM, Scaria, L, Joubert, L, Devassy, SM, Scaria, L, and Joubert, L

Abstract

BACKGROUND: Mental illness in parents impairs their parenting capability, which has a lifelong detrimental impact on their children's physical and psychological health. In the current Indian context, due to weak social security nets, family is the only plausible intervention to ensure adequate substitute child care. Therefore, this study explores various risk factors and barriers to providing substitute family care. METHODS: We used a mixed-method approach to gather information from 94 substitute family caregivers. Quantitative screening data were collected from four hospitals using a clinical data mining tool and an interview guide to gather caregiver perspectives on economic, familial, and social risks and barriers associated with caring. We used thematic analysis to consolidate the qualitative findings. RESULTS: Most of the substitute caregivers were females from low-income households. The study identified 11 sub-themes and 23 specific themes associated with risks and barriers to substitute care. These themes fell into four broad areas: economic, familial, school-related risks, and specific cultural and service access barriers. Focus on economic interventions is likely to result in strengthening the substitute family caregiver. CONCLUSION: The paradigmatic shift of treatment focus from the patient to the entire household would benefit the children just as it does the patient.

Published
2022

32. First cases of Omicron in France are exhibiting mild symptoms, November 2021–January 2022

Author

Maisa, A., primary, Spaccaferri, G., additional, Fournier, L., additional, Schaeffer, J., additional, Deniau, J., additional, Rolland, P., additional, Coignard, B., additional, Andrieu, A., additional, Broustal, O., additional, Chene, S., additional, Chent, S., additional, Fougère, E., additional, Gbaguidi, G., additional, Hamidouche, M., additional, Lamy, A., additional, Mano, Q., additional, Mastrovito, B., additional, Mercier, A., additional, Modenesi, G., additional, Picard, G., additional, Prudhomme, J., additional, Rapilly, F., additional, Riondel, A., additional, Rivière, M., additional, Villegas Ramirez, B., additional, Zhu-Soubise, A., additional, Zurbaran, M., additional, Amzert, A., additional, Andreoletti, L., additional, Bal, A., additional, Beaurepere, R., additional, Behillil, S., additional, Belec, L., additional, Bernard, C., additional, Bocket, L., additional, Bouri, L., additional, Bourlet, T., additional, Bressollette-Bodin, C., additional, Brichler, S., additional, Brugerolles, C., additional, Cado, S., additional, Calvez, V., additional, Capron, N., additional, Castelain, S., additional, Castro-Alvarez, J., additional, Chaix, M.-L., additional, Charpentier, C., additional, Che, D., additional, Chillou, C., additional, Colson, P., additional, Coudene, P., additional, Crinquette, A., additional, De Rougemont, A., additional, Delagrèverie, H., additional, Delamare, C., additional, Denecker-Berardino, T., additional, Descamps, D., additional, Desroches, M., additional, Destras, G., additional, Dos Santos, G., additional, Ducancelle, A., additional, Ducreux, S., additional, Duret, T., additional, Enouf, V., additional, Fafi-Kremer, S., additional, Felici, C., additional, Fourati, S., additional, Fournier, P.-E., additional, Gaudy, C., additional, Germain, H., additional, Giordanengo, V., additional, Gorge, O., additional, Haim-Boukobza, S., additional, Henquell, C., additional, Holstein, A., additional, Houhamdi, L., additional, Izopet, J., additional, Jacomo, V., additional, Jacques, A., additional, Jaffar-Bandjee, M.-C., additional, Jimenez, M., additional, Josset, L., additional, Kemeny, S., additional, Lafon, M.-E., additional, Le Bars, A., additional, Le Corguille, G., additional, Lepiller, Q., additional, Levasseur, A., additional, Leveque, N., additional, Lina, B., additional, Madelaine, C., additional, Malabat, C., additional, Marque-Juillet, S., additional, Martin-Dunavit, T., additional, Mavingui, P., additional, Merens, A., additional, Messak, I., additional, Morand-Joubert, L., additional, Naudot, X., additional, Neybecker, P., additional, Pawlotsky, J.-M., additional, Pilorge, L., additional, Plantier, J.-C., additional, Poggi, C., additional, Pretet, M., additional, Ragot, C., additional, Raoul, H., additional, Rogez, S., additional, Roque-Afonso, A.-M., additional, Roquebert, B., additional, Rousset, D., additional, Rozenberg, F., additional, Sagot, C., additional, Sahnoune, S., additional, Salgado, D., additional, Sand, O., additional, Saudemont, C., additional, Schvoerer, E., additional, Simon-Loriere, E., additional, Stephan, R., additional, Sudour, J., additional, Thibault, V., additional, Tuaillon, E., additional, Vabret, A., additional, Vallee, E., additional, Van Der Werf, S., additional, Van Helden, J., additional, Verdurme, L., additional, Vignola, A., additional, Wilkinson, D., additional, and Yazdanpanah, Y., additional

Published
2022
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35. Virological failure of patients on maraviroc-based antiretroviral therapy

Author

Raymond, Stéphanie, Maillard, Anne, Amiel, Corinne, Peytavin, Gilles, Trabaud, Mary Anne, Desbois, Delphine, Bellecave, Pantxika, Delaugerre, Constance, Soulie, Cathia, Marcelin, Anne Geneviève, Descamps, Diane, Izopet, Jacques, Reigadas, S., Bellecave, P., Pinson-Recordon, P., Fleury, H., Masquelier, B., Signori-Schmuck, A., Morand, P., Bocket, L., Mouna, L., André, P., Tardy, J. C., Trabaud, M. A., Descamps, D., Charpentier, C., Peytavin, G., Brun-Vézinet, F., Haim-Boukobza, S., Roques, A. M., Soulié, C., Lambert-Niclot, S., Malet, I., Wirden, M., Fourati, S., Marcelin, A. G., Calvez, V., Flandre, P., Assoumou, L., Costagliola, D., Morand-Joubert, L., Delaugerre, C., Schneider, V., Amiel, C., Giraudeau, G., Maillard, A., Nicot, F., and Izopet, J.

Published
2015
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38. A faceta integralizadora da disciplina Resolução de Problemas do PROFMAT na Universidade Federal do Oeste da Bahia: Uma análise quantitativa

Author

Marcelo De Paula and Joubert Lima Ferreira

Subjects
Resolução, Problemas, Formação, PROFMAT, Special aspects of education, LC8-6691, Mathematics, QA1-939
Abstract

Este artigo apresenta a faceta integralizadora do componente curricular Resolução de Problemas do mestrado PROFMAT da Universidade Federal do Oeste da Bahia em relação aos demais componentes curriculares. Por meio de um estudo do rendimento acadêmico dos estudantes, mensuramos qual a sua relação com os demais componentes, e se há causalidade. Fazemos uma análise descritiva, seguida de uma análise inferencial para comparação dos rendimentos médios e apresentamos uma modelagem estatística por regressão assumindo o componente Resolução de Problemas como variável resposta e os demais componentes como variáveis explicativas, para detectar quais componentes explicam de fato o seu rendimento e o seu caráter integralizador no contexto da matriz curricular. O banco de dados foi obtido via solicitação à PROTIC-UFOB sem a identificação nominal dos estudantes. Em relação aos resultados, a análise descritiva mostrou que o componente curricular Avaliação Educacional apresentou o maior rendimento médio e a menor variabilidade (Coeficiente de Variação: CV=3,2%) e o componente curricular Probabilidade e Estatística apresentou o menor rendimento médio e a maior variabilidade (Coeficiente de Variação: CV=26,3%). Em relação à análise inferencial por meio da análise de variância (ANOVA) constatamos que há diferença significativa entre os rendimentos médios dos componentes curriculares ministrados no PROFMAT-UFOB (Valor-p < 0,05). No âmbito da modelagem estatística por regressão, os componentes curriculares que, de fato, contribuem ou influenciam no rendimento acadêmico do componente Resolução de Problemas são dois (i) Matemática Discreta e (ii) Números e Funções Reais, caracterizando a atual faceta integralizadora do componente.

Published
2024
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40. High seroconversion rate but low antibody titers after two injections of BNT162b2 (Pfizer-BioNTech) vaccine in patients treated with chemotherapy for solid cancers

Author

Palich, R., primary, Veyri, M., additional, Vozy, A., additional, Marot, S., additional, Gligorov, J., additional, Benderra, M.-A., additional, Maingon, P., additional, Morand-Joubert, L., additional, Adjoutah, Z., additional, Marcelin, A.-G., additional, Spano, J.-P., additional, and Barrière, J., additional

Published
2021
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41. Four year follow-up of simplification therapy with once-daily emtricitabine, didanosine and efavirenz in HIV-infected patients (ALIZE ANRS 099 trial)

Author

Gallien, Sébastien, Journot, Valérie, Rozenbaum, Willy, Yéni, Patrick, Morlat, Philippe, Poizot-Martin, Isabelle, Reynes, Jacques, Reliquet, Véronique, Leclercq, Pascale, Simon, François, Chêne, Geneviève, Molina, Jean-Michel, Molina, J.-M., Chêne, G., Rancinan, C., Collin, F., Journot, V., Ferchal, F., Morand-Joubert, L., Palmer, P., Charrois, A., Molina, J.-M., Chêne, G., Journot, V., Rancinan, C., Madelaine, I., Morlat, P., Rozenbaum, W., Sereni, D., Vilde, J. L., Ferchal, F., Morand-Joubert, L., Poizot-Martin, I., Rosenthal, E., Raffi, F., and Reynes, J.

Published
2011
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43. Integrated care improves risk-factor modification after stroke: initial results of the Integrated Care for the Reduction of Secondary Stroke Model

Author

Joubert, J., Reid, C., Barton, D., Cumming, T., McLean, A., Joubert, L., Barlow, J., Ames, D., and Davis, S.

Subjects
Interdisciplinary approach in education -- Models, Interdisciplinary approach in education -- Research, Stroke (Disease) -- Care and treatment, Stroke (Disease) -- Complications and side effects, Stroke (Disease) -- Risk factors, Stroke (Disease) -- Research, Practice guidelines (Medicine) -- Usage, Diseases -- Relapse, Diseases -- Risk factors, Diseases -- Prevention, Diseases -- Research, Health, Psychology and mental health
Published
2009

45. PROVE-Pre-Eclampsia Obstetric Adverse Events: Establishment of a Biobank and Database for Pre-Eclampsia

Author

Bergman, L, Bergman, K, Langenegger, E, Moodley, A, Griffith-Richards, S, Wikstrom, J, Hall, D, Joubert, L, Herbst, P, Schell, S, van Veen, T, Belfort, M, Tong, SYC, Walker, S, Hastie, R, Cluver, C, Bergman, L, Bergman, K, Langenegger, E, Moodley, A, Griffith-Richards, S, Wikstrom, J, Hall, D, Joubert, L, Herbst, P, Schell, S, van Veen, T, Belfort, M, Tong, SYC, Walker, S, Hastie, R, and Cluver, C

Abstract

Pre-eclampsia is a leading cause of maternal and perinatal morbidity and mortality. The burden of disease lies mainly in low-middle income countries. The aim of this project is to establish a pre-eclampsia biobank in South Africa to facilitate research in the field of pre-eclampsia with a focus on phenotyping severe disease.The approach of our biobank is to collect biological specimens, detailed clinical data, tests, and biophysical examinations, including magnetic resonance imaging (MRI) of the brain, MRI of the heart, transcranial Doppler, echocardiography, and cognitive function tests.Women diagnosed with pre-eclampsia and normotensive controls are enrolled in the biobank at admission to Tygerberg University Hospital (Cape Town, South Africa). Biological samples and clinical data are collected at inclusion/delivery and during the hospital stay. Special investigations as per above are performed in a subset of women. After two months, women are followed up by telephonic interviews. This project aims to establish a biobank and database for severe organ complications of pre-eclampsia in a low-middle income country where the incidence of pre-eclampsia with organ complications is high. The study integrates different methods to investigate pre-eclampsia, focusing on improved understanding of pathophysiology, prediction of organ complications, and potentially future drug evaluation and discovery.

Published
2021

47. National sentinel surveillance of transmitted drug resistance in antiretroviral-naive chronically HIV-infected patients in France over a decade: 2001–2011

Author

Descamps, Diane, Assoumou, Lambert, Chaix, Marie-Laure, Chaillon, Antoine, Pakianather, Sophie, de Rougemont, Alexis, Storto, Alexandre, Dos Santos, Georges, Krivine, Anne, Delaugerre, Constance, Montes, Brigitte, Izopet, Jacques, Charpentier, Charlotte, Wirden, Marc, Maillard, Anne, Morand-Joubert, Laurence, Pallier, Coralie, Plantier, Jean-Christophe, Guinard, Jérôme, Tamalet, Catherine, Cottalorda, Jacqueline, Marcelin, Anne-Geneviève, Desbois, Delphine, Henquell, Cecile, Calvez, Vincent, Brun-Vézinet, Françoise, Masquelier, Bernard, Costagliola, Dominique, Lagier, E., Roussel, C., Le Guillou-Guillemette, H., Alloui, C., Bettinger, D., Anies, G., Reigadas, S., Bellecave, P., Pinson-Recordon, P., Fleury, H., Masquelier, B., Vallet, S., Leroux, M., Dina, J., Vabret, A., Poveda, J. D., Mirand, A., Henquell, C., Bouvier-Alias, M., Noel, C., De Rougemont, A., Dos Santos, G., Yerly, S., Gaille, C., Caveng, W., Chapalay, S., Calmy, A., Signori-Schmuck, A., Morand, P., Pallier, C., Bocket, L., Mouna, L., Ranger-Rogez, S., André, P., Tardy, J. C., Trabaud, M. A., Tamalet, C., Delamare, C., Montes, B., Schvoerer, E., André-Garnier, E., Férré, V., Cottalorda, J., Guigon, A., Guinard, J., Descamps, D., Charpentier, C., Peytavin, G., Brun-Vézinet, F., Haim-Boukobza, S., Roques, A. M., Soulié, C., Lambert-Niclot, S., Malet, I., Wirden, M., Fourati, S., Marcelin, A. G., Calvez, V., Flandre, P., Assoumou, L., Costagliola, D., Morand-Joubert, L., Delaugerre, C., Schneider, V., Amiel, C., Giraudeau, G., Maillard, A., Plantier, J. C., Fafi-Kremer, S., Schmitt, M. P., Raymond, S., Izopet, J., Chaillon, A., Barin, F., and Marque Juillet, S.

Published
2013
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48. ESC Core Curriculum for the General Cardiologist (2013)

Author

Gillebert, Thierry C., Brooks, Nicholas, Fontes-Carvalho, Ricardo, Fras, Zlatko, Gueret, Pascal, Lopez-Sendon, Jose, Salvador, Maria Jesus, van den Brink, Renee B. A., Smiseth, Otto A., Griebenow, Reinhard, Kearney, Peter, Vahanian, Alec, Bauersachs, J., Bax, J., Burri, H., Caforio, A.L.P., Calvo, F., Charron, P., Ertl, G., Flachskampf, F., Giannuzzi, P., Gibbs, S., Gonçalves, L., González-Juanatey, J.R., Hall, J., Herpin, D., Iaccarino, G., Iung, B., Kitsiou, A., Lancellotti, P., McDonough, T., Monsuez, J.J., Nuñez, I.J., Plein, S., Porta-Sánchez, A., Priori, S., Price, S., Regitz-Zagrosek, V., Reiner, Z., Ruilope, L.M., Schmid, J.P., Sirnes, P. A., Sousa-Ouva, M., Stępińska, J., Szymanski, C., Taggart, D., Tendera, M., Tokgözog[Combining Caron]lu, L., Trindade, P., Zeppenfeld, K., Joubert, L., and Carrera, C.

Published
2013
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50. HIV-1 integrase variability and relationship with drug resistance in antiretroviral-naive and -experienced patients with different HIV-1 subtypes

Author

Reigadas, S., Marcelin, A. G., Houssaïni, A., Yerly, S., Descamps, D., Plantier, J. C., Ruffault, A., Amiel, C., Trabaud, M. A., Flandre, Philippe, Fleury, H., Masquelier, B., Roussel, C., Alloui, C., Leguillou-Guillemette, H., Bettinger, D., Pallier, C., Descamps, D., Brun-Vezinet, F., Peytavin, G., Masquelier, B., Pinson, P., Reigadas, S., Vallet, S., Poveda, J. D., Mirand, A., Krivine, A., Auvray, C., de Rougemont, A., Yerly, S., Signori-Schmuck, A., Bocket, L., Rogez, S., Tamalet, C., Schneider, V., Amiel, C., Bouvier-Alias, M., Montes, B., Schvoerer, E., Ferré, V., Chaix, M. L., Guinard, J., Haim-Boukobza, S., Soulié, C., Marcelin, A. G., Flandre, P., Assoumou, L., Calvez, V., Maillard, A., Morand-Joubert, L., Chaplain, C., Delaugerre, C., Bourlet, T., Bertsch, S., Plantier, J. C., Raymond, S., and Marque-Juillet, S.

Published
2013
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