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Confluent and reticulate papillomatosis (CRP) is an idiopathic disorder characterized by persistent patches and plaques that are centrally confluent and peripherally reticulate. Although CRP primarily occurs sporadically, there may be a familial predisposition to the development of CRP. Minocycline has been reported as effective in the treatment of CRP, seemingly due to its antimicrobial and anti-inflammatory activity. We describe a case of familial CRP involving 2 brothers who were successfully treated with minocycline.

Amelanotic malignant melanoma (AMM) is characterized by little or no visible pigment. The diagnosis of AMM is a challenge for clinicians because it is a rare entity that presents with various clinical features. We describe a case of AMM on the lower lip in a 63-year-woman, which manifested as an erythematous mass that resembled grouped papules.