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6. Reference Ranges of Ventricular Morphology and Function in Healthy Chinese Adults: A Multicenter 3 T MRI Study

Author

Xu, Ziqian, primary, Li, Weihao, additional, Wang, Jiaqi, additional, Wang, Fei, additional, Sun, Bin, additional, Xiang, Shifeng, additional, Luo, Xiao, additional, Meng, Yanfeng, additional, Wang, Xiang, additional, Wang, Ximing, additional, Song, Jianxun, additional, Zhang, Min, additional, Xu, Dinghu, additional, Zhou, Xiaoyue, additional, Ju, Zhiguo, additional, Sun, Jiayu, additional, Han, Yuchi, additional, and Chen, Yucheng, additional

Published
2023
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7. Reference Ranges of Ventricular Morphology and Function in Healthy Chinese Adults: A Multicenter 3 T MRI Study.

Author

Xu, Ziqian, Li, Weihao, Wang, Jiaqi, Wang, Fei, Sun, Bin, Xiang, Shifeng, Luo, Xiao, Meng, Yanfeng, Wang, Xiang, Wang, Ximing, Song, Jianxun, Zhang, Min, Xu, Dinghu, Zhou, Xiaoyue, Ju, Zhiguo, Sun, Jiayu, Han, Yuchi, and Chen, Yucheng

Subjects
MORPHOLOGY, MAGNETIC resonance imaging, MANN Whitney U Test, AGE groups, BODY surface area
Abstract

Background: Magnetic resonance imaging (MRI) reference ranges for ventricular morphology and function in the Chinese population are lacking. Purpose: To establish the MRI reference ranges of left and right ventricular (LV and RV) morphology and function based on a large multicenter cohort. Study Type: Prospective. Population: One thousand and twelve healthy Chinese Han adults. Field Strength/Sequence: Balanced steady‐state free procession cine sequence at 3.0 T. Assessment: Biventricular end‐diastolic, end‐systolic, stroke volume, and ejection fraction (EDV, ESV, SV, and EF), LV mass (LVM), end‐diastolic and end‐systolic dimension (LVEDD and LVESD), anteroseptal wall thickness (AS), and posterolateral wall thickness (PL) were measured. Body surface area (BSA) and height were used to index biventricular parameters. Parameters were compared between age groups and sex. Statistical Tests: Independent‐samples t‐tests or Mann–Whitney U test to compare mean values between sexes; ANOVA or Kruskal–Wallis test to compare mean values among age groups; linear regression to assess the relationships between cardiac parameters and age (correlation coefficient, r). A P value <0.05 was considered statistically significant. Results: The biventricular volumes, LVM, LVEDD, RVEDV/LVEDV ratio, LVESD, AS, and PL were significantly greater in males than in females, even after indexing to BSA or height, while LVEF and RVEF were significantly lower in males than in females. For both sexes, age was significantly negatively correlated with biventricular volumes (male and female: LVEDV [r = −0.491; r = −0.373], LVESV [r = −0.194; r = −0.184], RVEDV [r = −0.639; r = −0.506], RVESV [r = −0.270; r = −0.223]), with similar correlations after BSA normalization. LVEF (r = 0.043) and RVEF (r = 0.033) showed a significant correlation with age in females, but not in males (P = 0.889; P = 0.282). Data Conclusion: MRI reference ranges for biventricular morphology and function in Chinese adults are presented and show significant associations with age and sex. Level of Evidence: 2 Technical Efficacy: Stage 2 [ABSTRACT FROM AUTHOR]

Published
2024
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21. Effects of Plant Growth Substances on Biomass and Lipid Production in Diatoms

Author

Ju Zhiguo, Ding Zhen, Li Kangjun, Li Yuan, Ding Lixiao, and Zhang Qingna

Subjects
lcsh:GE1-350, Plant growth, Biomass, food and beverages, Stage ii, Chloride, chemistry.chemical_compound, Increased lipid, chemistry, Botany, Pinnularia gibba, medicine, lipids (amino acids, peptides, and proteins), Food science, Abscisic acid, Gibberellic acid, lcsh:Environmental sciences, General Environmental Science, medicine.drug, Plant growth regulator biomass lipids micro algae diatoms
Abstract

The effects of plant growth stimulating substances like naphthalene-acetic acid (NAA), Gibberellic acid 3 (GA 3 ) and 6-benzylaminopurine (6-BA), or plant growth inhibiting substances like abscisic Acid (ABA) and ((2-chloroethyl) trimethylammonium chloride) (CCC), or their combinations, on biomass and lipid production in Pinnularia gibba var. linearis and Chaetoceros gracilis were studied. When applied at day 1 (stage I), treatments with NAA, GA 3 and 6-BA or their combinations enhanced biomass production but reduced lipid contents. The total lipids, however, were higher in these treatments than that in the control. 6-BA was more effective in stimulating total lipid production. No difference was found among the treatments with NAA, GA 3 or their combination. Adding NAA or GA 3 to 6-BA did not enhance biomass or lipid production compared with 6-BA alone. When applied at day 4 (stage II), growth stimulating substances increased biomass production compared with the control but did not affect total lipid production. Less biomass was obtained when the treatments were applied at day 4 compared with that applied at day 1. Treatments with growth inhibitors like ABA, CCC or ABA + CCC at day 1 reduced biomass production and total lipids, although lipid contents were increased by the treatments. When treated with ABA, CCC and ABA + CCC at day 4 , however, they did not reduce biomass production while increased lipid contents and total lipids.

Published
2013

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