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6 results on '"Ju-Wei Shao"'

1. An analysis of the correlation between diabetic retinopathy and preretinal oxygen tension using three-dimensional spoiled gradient-recalled echo sequence imaging

Author

Min-Jie Zhou, Ju-Wei Shao, Jian Pu, Shu-Tian Xiang, Yi Liang, Qian He, Wei Su, and Cheng Liu

Subjects
Hyperglycemia, Diabetic retinopathy, Oxygen tension, Magnetic resonance imaging, Three-dimensional spoiled gradient-recalled echo, Medical technology, R855-855.5
Abstract

Abstract Background The aims of this study were to evaluate the levels of preretinal oxygen tension in patients with diabetes who did not have hypertension by using three-dimensional spoiled gradient-recalled (3D-SPGR) echo sequence imaging and to explore the correlation between diabetic retinopathy (DR) and changes in preretinal oxygen tension. Method This study involved 15 patients with type 2 diabetes without hypertension, who were divided into a diabetic retinopathy (DR) group (n = 10 eyes) and a diabetic non-retinopathy (NDR) group (n = 20 eyes), according to the results of a fundus photography test. Another healthy control group (n = 14 eyes) also participated in the study. The preretinal vitreous optic disc area, nasal side, and temporal side signal intensity of the eyes was assessed before and after oxygen inhalation with the use of 3D-SPGR echo magnetic resonance imaging (MRI). The signal acquisition time was 10, 20, 30, 40, and 50 min after oxygen inhalation. Results The results showed that, in the DR and NDR groups, the preretinal vitreous oxygen tension increased rapidly at 10 min after oxygen inhalation and peaked at 30–40 min, and the increased slope of the DR group was higher than that of the NDR group. The oxygen tension of the preretinal vitreous gradually increased after oxygen inhalation, and the difference between the DR and NDR groups and the control group was statistically significant (P

Published
2022
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2. Correlation Between IVIM-DWI Parameters and Pathological Classification of Idiopathic Orbital Inflammatory Pseudotumors: A Preliminary Study

Author

Jian Pu, Yi Liang, Qian He, Ju-Wei Shao, Min-Jie Zhou, Shu-Tian Xiang, Ying-Wen Li, Jian-Bo Li, and Shun-Jun Ji

Subjects
orbital cavity, inflammatory pseudotumor, magnetic resonance imaging, incoherent motion in voxels, pathology, typing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

ObjectiveTo investigate the correlation between intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) and the pathological classification of idiopathic orbital inflammatory pseudotumors (IOIPs).MethodsNineteen patients who were diagnosed with IOIPs (a total of 24 affected eyes) between November 2018 and December 2020 were included in the study. All the patients underwent magnetic resonance imaging orbital plain scans and IVIM-DWI multiparameter scans before an operation. The true diffusion coefficient (D), pseudodiffusion coefficient (D*), and perfusion fraction (f) values were obtained. Based on histopathology, the lesions were divided into three types: lymphocytic infiltration, fibrosclerotic, and mixed. The correlation between IVIM-DWI parameters and pathological classification was tested with the histopathological results as the gold standard. The data were analyzed using SPSS version 17.0, with P < 0.05 defined as significant.ResultsAmong the 19 patients (24 eyes) affected by IOIP, there were no significant differences between IOIP pathological classification and gender or age (P > 0.05). There were statistically significant differences between the D and f values for different pathological types of IOIP and IVIM parameters (P < 0.05), and there was no significant difference in D* value between the different pathological types (P > 0.05).ConclusionThe D and f values showed correlation with different types of IOIP, and the sensitivity of the D value was higher than that of the f value. The D* value showed no significant distinction between pathological types of IOIP.

Published
2022
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3. CT and MRI findings in relapsing primary malignant melanoma of the lacrimal sac: a case report and brief literature review

Author

Ju-Wei Shao, Jian-Hua Yin, Shu-Tian Xiang, Qian He, Hong Zhou, and Wei Su

Subjects
Ophthalmology, RE1-994
Abstract

Abstract Background Primary lacrimal sac melanoma is an extremely rare condition with fewer than 50 cases reported so far. Clinically, its symptoms resemble those of dacryocystitis, leading to frequent misdiagnosis. During diagnosis, imaging examination is often performed to differentiate tumors from inflammation. In this report, we present a case of primary lacrimal sac melanoma and summarize the CT and MRI characteristics of lacrimal sac melanoma. Case presentation We report a 50-year-old female patient who had undergone a dacryocystectomy for the left lacrimal sac mass. Postoperative pathological examination confirmed the presence of primary malignant melanoma. Three months later, a lump in the lacrimal sac area was found. The patient underwent CT and MR examinations. CT scan demonstrated a partially well-defined soft mass in the fossa of left lacrimal sac extending into the nasolacrimal duct and anterior ethmoid sinus. MRI revealed an intermediate signal intensity on T1 and iso-or hyper-signal on T2 weighted images. Histopathological examination on biopsy confirmed recurrence of primary lacrimal sac melanoma. Discussion and conclusions None has described the CT and MR findings of primary lacrimal sac melanoma so far. Typically, MR images show hyperintensity signal on T1-weighted images and hypointense signal on T2-weighted images owing to the paramagnetic properties of melanin. In contrast to previous reports and the present case, most cases do not present these typical signals. Thus, reporting such radiological findings is important to create awareness on variant images of primary lacrimal sac melanoma. This will reduce misdiagnosis and mistreatment.

Published
2020
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4. Correlation Between IVIM-DWI Parameters and Pathological Classification of Idiopathic Orbital Inflammatory Pseudotumors: A Preliminary Study

Author

Jian Pu, Yi Liang, Qian He, Ju-Wei Shao, Min-Jie Zhou, Shu-Tian Xiang, Ying-Wen Li, Jian-Bo Li, and Shun-Jun Ji

Subjects
Cancer Research, Oncology
Abstract

ObjectiveTo investigate the correlation between intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) and the pathological classification of idiopathic orbital inflammatory pseudotumors (IOIPs).MethodsNineteen patients who were diagnosed with IOIPs (a total of 24 affected eyes) between November 2018 and December 2020 were included in the study. All the patients underwent magnetic resonance imaging orbital plain scans and IVIM-DWI multiparameter scans before an operation. The true diffusion coefficient (D), pseudodiffusion coefficient (D*), and perfusion fraction (f) values were obtained. Based on histopathology, the lesions were divided into three types: lymphocytic infiltration, fibrosclerotic, and mixed. The correlation between IVIM-DWI parameters and pathological classification was tested with the histopathological results as the gold standard. The data were analyzed using SPSS version 17.0, with P < 0.05 defined as significant.ResultsAmong the 19 patients (24 eyes) affected by IOIP, there were no significant differences between IOIP pathological classification and gender or age (P > 0.05). There were statistically significant differences between the D and f values for different pathological types of IOIP and IVIM parameters (P < 0.05), and there was no significant difference in D* value between the different pathological types (P > 0.05).ConclusionThe D and f values showed correlation with different types of IOIP, and the sensitivity of the D value was higher than that of the f value. The D* value showed no significant distinction between pathological types of IOIP.

Published
2021

5. Three-dimensional-arterial spin labeling perfusion correlation with diabetes-associated cognitive dysfunction and vascular endothelial growth factor in type 2 diabetes mellitus rat

Author

Ying-Ying Zou, Qian He, Jing Fang, Shu-Tian Xiang, Ying Yang, Jin-De Wang, Wei Su, Jian-Bo Li, and Ju-Wei Shao

Subjects
medicine.medical_specialty, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Diabetes-associated cognitive dysfunction, Morris water navigation task, 030209 endocrinology & metabolism, Perfusion scanning, 030204 cardiovascular system & hematology, Hippocampus, Impaired glucose tolerance, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Diabetes mellitus, Internal medicine, Receptors, Internal Medicine, medicine, Hippocampus (mythology), business.industry, nutritional and metabolic diseases, Basic Study, medicine.disease, Streptozotocin, Perfusion imaging, Vascular endothelial growth factor, Endocrinology, chemistry, Cerebral blood flow, nervous system, Three-dimensional pseudo-continuous arterial spin labeling, business, Type 2, medicine.drug, circulatory and respiratory physiology
Abstract

Background Type 2 diabetes mellitus (T2DM) has been strongly associated with an increased risk of developing cognitive dysfunction and dementia. The mechanisms of diabetes-associated cognitive dysfunction (DACD) have not been fully elucidated to date. Some studies proved lower cerebral blood flow (CBF) in the hippocampus was associated with poor executive function and memory in T2DM. Increasing evidence showed that diabetes leads to abnormal vascular endothelial growth factor (VEGF) expression and CBF changes in humans and animal models. In this study, we hypothesized that DACD was correlated with CBF alteration as measured by three-dimensional (3D) arterial spin labeling (3D-ASL) and VEGF expression in the hippocampus. Aim To assess the correlation between CBF (measured by 3D-ASL and VEGF expression) and DACD in a rat model of T2DM. Methods Forty Sprague-Dawley male rats were divided into control and T2DM groups. The T2DM group was established by feeding rats a high-fat diet and glucose to induce impaired glucose tolerance and then injecting them with streptozotocin to induce T2DM. Cognitive function was assessed using the Morris water maze experiment. The CBF changes were measured by 3D-ASL magnetic resonance imaging. VEGF expression was determined using immunofluorescence. Results The escape latency time significantly reduced 15 wk after streptozotocin injection in the T2DM group. The total distance traveled was longer in the T2DM group; also, the platform was crossed fewer times. The percentage of distance in the target zone significantly decreased. CBF decreased in the bilateral hippocampus in the T2DM group. No difference was found between the right CBF value and the left CBF value in the T2DM group. The VEGF expression level in the hippocampus was lower in the T2DM group and correlated with the CBF value. The escape latency negatively correlated with the CBF value. The number of rats crossing the platform positively correlated with the CBF value. Conclusion Low CBF in the hippocampus and decreased VEGF expression might be crucial in DACD. CBF measured by 3D-ASL might serve as a noninvasive imaging biomarker for cognitive impairment associated with T2DM.

Published
2020

6. 320-slice CT angiography before hepatic intrahepatic portosystemic shunt for evaluating the puncture approach

Author

Zheng Lin Yang, Peng Wang, Ju Wei Shao, Na Ge, Wei Su, Jun Ren Zeng, Chong Wen Mao, Ying Wen Li, Shu Tian Xiang, and Qian He

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Cirrhosis, medicine.diagnostic_test, business.industry, Digital subtraction angiography, medicine.disease, Surgical planning, 030218 nuclear medicine & medical imaging, body regions, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Pediatrics, Perinatology and Child Health, Angiography, Medicine, Portal hypertension, 030211 gastroenterology & hepatology, Radiology, Portosystemic shunt, business, Vein, Computed tomography angiography
Abstract

Objective: This study aims to evaluate the value of 320 slice Computed Tomography Angiography (CTA) in evaluating puncture approaches by simulating Intrahepatic Portosystemic Shunt (IPS) in cirrhotic patients with portal hypertension. Methods: A total of 30 patients with hepatic cirrhosis and portal hypertension, who underwent IPS from November 2014 to January 2017 at Yunnan Province Second People's Hospital, were selected for this study. The CTA data acquired before surgery were retrospectively analysed. The puncture distances and puncture angles from the right hepatic vein, middle hepatic vein and left hepatic vein to the portal vein and its branches were measured and compared with those acquired by Digital Subtraction Angiography (DSA). Then, the differences between the puncture distances and angles acquired by CTA and DSA were evaluated. Results: Differences between puncture distances and angles acquired by CTA and DSA were not statistically significant (P>0.05). Conclusions: Puncture distances and angles acquired by CTA were consistent with those acquired by DSA. This can provide an imaging basis for the preoperative surgical planning of IPS.

Published
2018

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