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3 results on '"Juan Francisco Maldonado"'

1. Detection and partial characterization of antimutagenic compounds from white shrimp (Litopenaeus vannamei) cephalothorax

Author

Héctor-Enrique Trujillo-Ruiz, Carmen-María López-Saiz, Alejandro-Monserrat García-Alegría, Idalia Osuna-Ruiz, Hisila Del Carmen Santacruz-Ortega, María-Mercedes Meza-Montenegro, Juan-Francisco Maldonado-Escalante, Susana-Gabriela Cruz-Ramirez, and Armando Burgos Hernández

Subjects
Antioxidant, antimutagenic, bioactivity, by-product, shrimp, Nutrition. Foods and food supply, TX341-641, Food processing and manufacture, TP368-456
Abstract

Mutations are the result of effects produced by mutagenic agents, which may be responsible for the generation of chronic-degenerative diseases such as cancer. The aim of this work was to detect and characterize compounds with antimutagenic activity in white shrimp (Litopenaeus vannamei) cephalothorax. A serial extraction was carried out where different organic solvents, and its biological activity was evaluated. The antioxidant capacity was evaluated by DPPH and ABTS assay, where the methanol and water-soluble extracts had the highest antioxidant capacity. Antimutagenicity was evaluated by the Ames test, where the methanol-soluble extract showed the highest antimutagenic activity. The methanolic extract was fractionated by open column chromatography, the fractions obtained were determined antioxidant and antimutagenic activity and the ability to protect DNA from oxidative damage. Fraction H27 provided DNA the highest protection against the damage caused by H2O2. Partial chemical-characterization of fraction H27 suggests the presence of aromatic, hydroxylated, unsaturated compounds.

Published
2024
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2. Vamos pal perreo: Historias, argüendes, poemas y dibujos sobre reguetón

Author

Nadia Lartigue, Juan Francisco Maldonado, Isaura Leonardo, Jorge Comensals, Antonio Nieto, Yásyana Elena A. Gil, Irasema Fernández, Ollin Velasco, Rafa G. Escalona, Efraín Constantino Estrada, Ingrid Solana, Gabriel Elías, Zulema de la Rúa, Patricia Salinas, Jorge Carrasco, Nicté Toxqui, Rodrigo García Bonillas, Goy

Published
2021

3. An integrated health risk assessment of indigenous children exposed to arsenic in Sonora, Mexico

Author

Iram Mondaca Fernández, María Mercedes Meza Montenegro, R. Clark Lantz, Jefferey L. Burgess, Leticia Yañez Estrada, Ana Gabriela Dévora Figueroa, Diana Meza Figueroa, José de Jesús Balderas Cortés, Leticia García Rico, Juan Francisco Maldonado Escalante, and Marco Antonio Martínez Cinco

Subjects
021110 strategic, defence & security studies, medicine.medical_specialty, Health risk assessment, business.industry, Health, Toxicology and Mutagenesis, Ecological Modeling, Public health, 0211 other engineering and technologies, chemistry.chemical_element, 02 engineering and technology, Urine, Pollution, Comet assay, chemistry, Environmental health, Relative risk, Medicine, business, Cancer risk, ARSENIC EXPOSURE, Arsenic
Abstract

Exposure to inorganic arsenic (InAs) through drinking water, even at low to moderate concentrations, is a global public health problem. The objectives of this study were to estimate the risk ratio (HQ), cancer risk (R), and DNA damage (comet assay) of children from three indigenous Yaqui populations located in southern Sonora, Mexico, who were exposed to InAs through drinking water. A cross-sectional study was employed, and analysis of InAs in water and urine was performed via HPLC/ICP-MS. InAs levels in drinking water from Potam, Vicam, and Cocorit were 108.2, 36.0, and 6.2 μg/L−1 respectively. Children from Potam had arsenic concentrations in urine of 107.1 μg As L−1 compared with 40.3 μg As L−1 for the children of Cocorit. The HQ values for the children of Potam, Vicam, and Cocorit were 16.64, 6.02, and 0.94, while the R values were 9.4E-04, 3.5E-04, and 5.7E-05, respectively. Children with the highest arsenic exposure had significantly increased DNA damage (OTM = 14.4 vs. 4.3) [p < 0.0005] whi...

Published
2018
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