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The elderly population is growing driven by the increase in life expectancy, which in turn entails an increase in the number of people with chronic diseases such as dementia. The vast majority of people suffering from this illness is assisted by informal caregivers, who play a key role in fulfilling the patients#8217; needs, promoting the possibility for people with dementia to live in their home environment. The Internet as a support tool in psychoeducational programs can significantly improve accessibility of them, becoming a currently consolidated interactive resource for the training of patients with acute and chronic diseases, and their caregivers.A literature search of the Pubmed, PsyINFO, Scopus, SciELO and Psicodoc databases was performed to systematically review those studies related to web-based interventions for informal caregivers of people with dementia or cognitive impairment.On balance, the studies show a significant improvement after the psychoeducational intervention. Specifically, the improvement in caregivers#8217; wellbeing can be observed in the measures for self-efficacy, anxiety and depression.Online interventions are a promising strategy for the care of people with dementia. It would be advisable to perform further randomized trials to assess the reasons for lack of adherence to intervention, as well as usability studies to test the different software programs used.

Tryptophan, serotonin, and melatonin, present in Jerte Valley cherries, participate in sleep regulation and exhibit antioxidant properties. The effect of the intake of seven different Jerte Valley cherry cultivars on the sleep-wake cycle, 6-sulfatoxymelatonin levels, and urinary total antioxidant capacity in middle-aged and elderly participants was evaluated. Volunteers were subjected to actigraphic monitoring to record and display the temporal patterns of their nocturnal activity and rest. 6-sulfatoxymelatonin and total antioxidant capacity were quantified by enzyme-linked immunosorbent assay and colorimetric assay kits, respectively. The intake of each of the cherry cultivars produced beneficial effects on actual sleep time, total nocturnal activity, assumed sleep, and immobility. Also, there were significant increases in 6-sulfatoxymelatonin levels and total antioxidant capacity in urine after the intake of each cultivar. These findings suggested that the intake of Jerte Valley cherries exerted positive effect on sleep and may be seen as a potential nutraceutical tool to counteract oxidation.

Summary Background & aims The relationship between diet and health has led to intense research into bioactive compounds in foods. The present study evaluated the effect of the consumption twice a day of a nutraceutical product made with Jerte Valley cherries (Caceres, Extremadura, Spain) on nocturnal rest, urinary 6-sulfatoxymelatonin (aMT6-s), and urinary antioxidant capacity in young (20–30 yr-old), middle-aged (45–55 yr-old), and elderly (65–75 yr-old) subjects. Methods In volunteers ( n = 6 per age group), the temporal patterns of the individuals' activity and rest were recorded by actigraphic monitoring. For the quantification of aMT6-s, a commercial ELISA kit was used, and total antioxidant capacity was evaluated by means of a colorimetric assay kit. Results The intake of the product increased significantly the Actual Sleep Time and Immobility, and decreased significantly the Total Nocturnal Activity in all subjects. Moreover, it increased significantly the urinary aMT6-s and antioxidant capacity in all subjects with respect to their basal values. Conclusions The consumption of a nutraceutical product made with Jerte Valley cherries improves nocturnal rest and has an antioxidant effect in humans.