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2. Databases for Congenital Heart Defect Public Health Studies Across the Lifespan

Author

Tiffany J. Riehle‐Colarusso, Lisa Bergersen, Craig S. Broberg, Cynthia H. Cassell, Darryl T. Gray, Scott D. Grosse, Jeffrey P. Jacobs, Marshall L. Jacobs, Russell S. Kirby, Lazaros Kochilas, Asha Krishnaswamy, Arianne Marelli, Sara K. Pasquali, Thalia Wood, Matthew E. Oster, Ginnie Lee Abarbanell, Faith Adams, Steven W. Allen, Sydney Allen, Anand Ambrose, Carl Lewis Backer, Andrea Baer, Carissa Marie Baker‐Smith, Mona Barmash, Amy Basken, Cassandra Bates, Sarosh Percy Batlivala, Robert H. Beekman, John William Belmont, Joshua Benke, Stuart Berger, JR Bockerstette, Jeffrey R. Boris, Lorenzo Botto, Jackie Boucher, Dana Brock Hageman, Cheryl Brosig Soto, Kristin Marie Burns, Lenore Cameron, Robert M. Campbell, Steven E. Colan, Lynn Colegrove, Christina Coleman, Angie Colson, Adolfo Correa, Pamela Costa, Chris Couser, Melissa Lynnn Crenshaw, Tessa Crume, Rachel Daskalov, Mark D. Del Monte, Lindsay DeSantis, Kaitlin Doherty, Kenneth Dooley, Charles (Wes) Duke, Pirooz Eghtesady, Saiza Elayda, Alison Ellison, Tim Elsner, Cori Erntz, Michelle Z. Esquivel, Bethany Evans, Lloyd Robert Feit, Marcia Feldkamp, William Foley, Elyse Foster, Wayne Franklin, Bridget Freeley, Frank M. Galioto, Mary George, Michael H. Gewitz, Katja Michelle Gist, Thomas Glenn, Melissa (Jill) Glidewell, Lorraine A. Gore, Johanna Gray, Hannah Green, Michelle Z. Gurvitz, Sonia Handa, Melissa Harvey, Emilie Heath, Danielle Hile, John Smith Hokanson, Margaret (Peggy) Honein, Marius M. Hubbell, Jeff Hudson, Kelly Huhn, Dawn Ilardi, Dawn C. Jacobs, Robert Douglas Benjamin Jaquiss, Kathy J. Jenkins, Anitha John, Patrick Johnson, Shakila Johnson, Emily Jones, Antonios P. Jossif, Jonathan Ross Kaltman, David Kasnic, Alex R. Kemper, Natalie Kenny, Paul Khairy, Valerie King, Donna Knapp, Daisuke Kobayashi, Adrienne Kovacs, James Kucik, Karen S. Kuehl, Alexandra Kuznetsov, Scott Leezer, Jodi Lemacks, Patty Libby, Paul H. Lipkin, Michele Ann Lloyd‐Puryear, Keila Natilde Lopez, Nicolas L. Madsen, Cara Mai, Monica Mann, Bradley Marino, Gerard Robert Martin, G. Paul Matherne, Phillip Mauller, Susan May, Edward R. B. McCabe, Nancy McCabe, Michelle McCardle, Ty McCathran, Amy McCathran, Michael E. McConnell, Kristine Brite McCormick, Eric Melsom, William Kelly Milionis, Paula Miller, Erika Miller, Stephanie Mitchell, Cynthia A. Moore, Laura Morris, Angela Murray, Kathleen Mussatto, Steven R. Neish, Sue Nelson, Jane W. Newburger, Jeremy Nicolarsen, Autumn Niggles, Jacqueline Anne Noonan, Gail Ober, Lori O'Keefe, Marc Overcash, Jennifer Page, Matthew Vaughn Park, Mehul D. Patel, Jasmin Patel, Gail Denise Pearson, Cindy Pellegrini, Corrie Pierce, Nelangi M. Pinto, Kara Polen, Jose Alcides Quinones, Carol Raimondi, Pat Richter, Michelle Rintamaki, Elisa Robles, Geoffrey L. Rosenthal, Grahame Rush, Laura Russell, Annamarie Saarinen, Craig Andrew Sable, Joel Saltz, Terri Schaefer, Kathryn Schubert, Vida Schwartz, Stuart K. Shapira, Kathleen Sheehan, Brenda Silverman, Regina Simeone, Juanita Smith, Kimberly E. Smith, Kristina Smith, Marci Sontag, Shubhika Srivastava, Corrie Stassen, Corey Stiver, Kathryn Taubert, Judy Thibadeau, John P. Thomas, Dena Thomas, Vivian Baldassari Thorne, Linda Tiernan, Susan Timmins, Colby Tiner, Natalie Torentinos, Glenn Tringali, James S. Tweddell, Lisa M. Vasquez, Amy Verstappen, Janice Ware, Caron Watkins, Catherine L. Webb, Ellen Weiss, Marina Weiss, Gil Wernovsky, Gretchen Whitehurst, Herbert Whitley, Jennifer Witten, Austin Henry Wong, Matthew Wright, Robert Wynbrant, and Bistra Zheleva

Subjects
Heart Defects, Congenital, Gerontology, medicine.medical_specialty, databases, Databases, Factual, Epidemiology, Heart defect, 030204 cardiovascular system & hematology, Global Health, Pediatrics, 03 medical and health sciences, Health services, 0302 clinical medicine, 030225 pediatrics, Contemporary Review, Global health, Humans, Medicine, Contemporary Reviews, Quality and Outcomes, Life span, business.industry, Public health, Health Services, congenital heart defects, Disease control, Public Health, Mortality/Survival, Morbidity, Cardiology and Cardiovascular Medicine, Mortality survival, business, public health science
Abstract

In a 2012 meeting at the Centers for Disease Control and Prevention (CDC), key experts and stakeholders identified public health knowledge gaps about congenital heart defects (CHDs), namely prevalence of CHDs across the life span, long‐term outcomes of persons with CHDs, and health services

Published
2016

3. Steady-State Pharmacokinetics of Rivastigmine in Patients with Mild to Moderate Alzheimer’s Disease Not Affected by Co-Administration of Memantine

Author

Joshua R. Shua-Haim, Juanita Smith, Françoise Pommier, Gilbert Lefèvre, Greg Sedek, Franck Picard, and Sandeep Athalye

Subjects
Male, Benzylamines, Evening, Phenylcarbamates, Rivastigmine, Phenols, Pharmacokinetics, Alzheimer Disease, Memantine, Phenethylamines, medicine, Humans, Pharmacology (medical), Aged, Cholinesterase, Aged, 80 and over, Cross-Over Studies, biology, business.industry, General Medicine, Middle Aged, Crossover study, Regimen, Area Under Curve, Concomitant, Anesthesia, biology.protein, Female, Cholinesterase Inhibitors, business, Excitatory Amino Acid Antagonists, medicine.drug
Abstract

Background and objective: It has been shown that combining memantine and a cholinesterase inhibitor, which each affect different neurotransmitter systems, may offer further improvements in efficacy over either treatment alone in patients with Alzheimer’s disease. The present study was conducted to determine if memantine has any effects on the steady-state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer’s disease. Methods: Rivastigmine-treated Alzheimer’s disease patients who had been maintained on a fixed regimen of twice-daily rivastigmine for ≥2 months were eligible to enter the study. Sixteen patients (seven males and nine females, age range 64–88 years, weight range 51.8–104 kg) were enrolled in this open-label, crossover tudy, which consisted of a 28-day screening period, a 36-hour baseline period, and a 35-day combination treatment phase. The patients spent the baseline period and day 35 at the study centre, where plasma samples for pharmacokinetic evaluation were taken at specified time intervals over a 10-hour time period. In addition, 10-hour (evening pre-dose) memantine plasma samples were taken on days 21, 34 and 35. Results: The combination of memantine (10 mg twice daily) with rivastigmine (1.5–6 mg twice daily) was safe and well tolerated. At each dose level of rivastigmine, the area under the concentration-time curve (AUC) values of rivastigmine and its metabolite as well as the metabolite-to-parent AUC ratios were unaffected by co-administration of memantine, confirming the absence of a meaningful pharmacokinetic drug-drug interaction. Conclusion: Under the study conditions, the extent of systemic exposure to rivastigmine and its metabolite NAP226-90 at steady state did not appear to be affected by concomitant administration of memantine.

Published
2008

4. Depression among Alzheimer's caregivers: Identifying risk factors

Author

Todd Haim, Yen-Hong Kuo, Juanita Smith, Yong Shi, and Joshua R. Shua-Haim

Subjects
Adult, Gerontology, Activities of daily living, Cross-sectional study, Disease, Logistic regression, 03 medical and health sciences, 0302 clinical medicine, 0504 sociology, Alzheimer Disease, Risk Factors, medicine, Humans, Depression (differential diagnoses), Aged, Aged, 80 and over, Depressive Disorder, Major, General Neuroscience, 05 social sciences, 050401 social sciences methods, Cognition, Middle Aged, medicine.disease, 030227 psychiatry, Psychiatry and Mental health, Clinical Psychology, Cross-Sectional Studies, Geriatric Depression Scale, Geriatrics and Gerontology, Alzheimer's disease, Psychology, Clinical psychology
Abstract

Purpose: The purpose of this study was to reveal risk factors contributing to the development of depression among caregivers of Alzheimer's disease patients.Methods: In a cross-sectional study, all caregivers of consecutive Alzheimer's disease patients were asked to participate in the study. Patient and caregiver depression was evaluated by using the Yesavage Geriatric Depression Scale (GDS). Information regarding patients' functional status, driving status, and type of behavioral abnormalities was obtained from caregivers. Patients' functional status was evaluated by using the Katz Activity of Daily Living (ADL) scale. The Folstein Mini-Mental Status Examination (MMSE) was used to evaluate cognition. Risk factors for Alzheimer's caregiver depression were assessed by means of logistic regression analysis.Results: A total of 92 patients and caregivers were evaluated. Fifteen were excluded due to incomplete data. A total of 77 pairs were included in this analysis. The age of caregivers ranged from 28 to 88 years. Mean (standard deviation [SD]) age was 63.1 (SD = 16.3) years old. Husbands and wives (caregivers) accounted for 49.4 percent; daughters or sons (or daughters-or sons-in-law) accounted for 42.9 percent. There were 29 caregivers (38 percent) found to be depressed. By using multivariate analysis, the following factors have been identified as risk factors for depression in Alzheimer's caregivers: depression in the dementia patient; ADL functional scores of 12 or greater; and the presence of hallucinations.Conclusion: Three risk factors were found to have a strong association with Alzheimer's caregiver depression. Early recognition of such risk factors may help to identify Alzheimer's caregivers with depression.

Published
2001

5. P3‐412: The impact of Alzheimer's support group activities on relatives of patients in long‐term care facilities

Author

Mira Ahuja, Suhas Patel, Tomer Shua-Haim, Juanita Smith, and Joshua R. Shua-Haim

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, medicine.medical_treatment, Support group, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Long-term care, Developmental Neuroscience, medicine, Neurology (clinical), Geriatrics and Gerontology, Psychiatry, business
Published
2012

6. P1‐340: The efficacy of dextromethorphan HBr and quinidine sulfate (Neudexta) treatment on agitation in patients with Alzheimer's disease: The caregivers' voice and clinical experience

Author

Juanita Smith and Joshua R. Shua-Haim

Subjects
Epidemiology, business.industry, Health Policy, Dextromethorphan hbr, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Quinidine Sulfate, Anesthesia, Medicine, In patient, Neurology (clinical), Geriatrics and Gerontology, business
Published
2012

7. P2‐165: Use of standard tests to predict the rate of cognitive deterioration in patients with Alzheimer's disease: A one‐year prospective study

Author

Camille Silay, Juanita Smith, Joshua R. Shua-Haim, and Suhas Patel

Subjects
Pediatrics, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Cognitive deterioration, Medicine, In patient, Neurology (clinical), Geriatrics and Gerontology, business, Prospective cohort study
Published
2010

8. Photosensitized oxidation of ascorbic acid in urine and blood serum

Author

Florence L. MacLeod, Juanita Smith Carr, and Mary L. Dodds

Subjects
Serum, Nutrition and Dietetics, Chromatography, Light, Medicine (miscellaneous), Riboflavin, Urine, Ascorbic Acid, Ascorbic acid, Light effect, chemistry.chemical_compound, Blood serum, Blood, chemistry, Biochemistry, Carbohydrate Metabolism, Humans, Dehydroascorbic acid, Oxidation-Reduction
Published
2010

9. P4–406: Safety & tolerability of memantine slow titration used in combination therapy with acetylcholinesterase inhibitor medications or as mono–therapy in the treatment of patients with vascular dementia and Alzheimer's disease. The caregiver's impression

Author

Suhas Patel, Evgenia Forman, Joshua R. Shua-Haim, and Juanita Smith

Subjects
medicine.medical_specialty, Combination therapy, Epidemiology, business.industry, medicine.drug_class, Health Policy, Memantine, Safety tolerability, Disease, medicine.disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Acetylcholinesterase inhibitor, Internal medicine, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Vascular dementia, medicine.drug
Published
2006

10. P4–404: Safety, tolerability & clinical impression of high dose rivastigmine treatment for patients with Alzheimer's disease

Author

Suhas Patel, Juanita Smith, and Joshua R. Shua-Haim

Subjects
Rivastigmine, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Safety tolerability, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Internal medicine, medicine, Neurology (clinical), Geriatrics and Gerontology, business, medicine.drug
Published
2006

11. P1–446: Safety & efficacy of oxcarbazepine in the treatment of hypersexuality in Alzheimer's disease patients residing in a special care unit in an assisted living facility

Author

Suhas Patel, Evgenia Forman, Juanita Smith, and Joshua R. Shua-Haim

Subjects
Special care unit, medicine.medical_specialty, Epidemiology, business.industry, Health Policy, media_common.quotation_subject, Assisted Living Facility, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Presentation, Developmental Neuroscience, Family medicine, medicine, Hypersexuality, Neurology (clinical), Geriatrics and Gerontology, medicine.symptom, business, Oxcarbazepine, medicine.drug, media_common
Published
2006

12. P4–403: Results of next day crossover of donepezil to extended release galantamine in Alzheimer's disease patients: A six–month follow up study

Author

Suhas Patel, Joshua R. Shua-Haim, Elena Regalman, and Juanita Smith

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Crossover, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Internal medicine, medicine, Galantamine, Neurology (clinical), Geriatrics and Gerontology, Extended release, Donepezil, business, medicine.drug, Month follow up
Published
2006

13. P4–401: Combination therapy of rivastigmine & memantine for the treatment of Alzheimer's disease: Safety, tolerability and the caregiver's voice

Author

Joshua R. Shua-Haim, Suhas Patel, Juanita Smith, and Evgenia Forman

Subjects
Rivastigmine, Pediatrics, medicine.medical_specialty, Combination therapy, Epidemiology, business.industry, Health Policy, media_common.quotation_subject, Memantine, S Voice, Safety tolerability, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Presentation, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, media_common, medicine.drug
Published
2006

14. P4–405: Combination therapy of long acting galantamine & memantine for the treatment of Alzheimer's disease: Safety, tolerability and the caregiver's voice. A cross section study after six months of treatment

Author

Suhas Patel, Joshua R. Shua-Haim, Juanita Smith, and Elena Regalman

Subjects
medicine.medical_specialty, Combination therapy, Epidemiology, business.industry, Cross-sectional study, Health Policy, Memantine, Safety tolerability, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Long acting, Developmental Neuroscience, Internal medicine, medicine, Galantamine, Neurology (clinical), Geriatrics and Gerontology, business, medicine.drug
Published
2006

15. P4–402: Galantamine delays nursing home transfers in Alzheimer's disease (AD) patients residing in assisted living facilities

Author

Suhas Patel, Sonia Rijhsinghani, Juanita Smith, and Joshua R. Shua-Haim

Subjects
Gerontology, Epidemiology, business.industry, Health Policy, Assisted Living Facility, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Galantamine, Medicine, Neurology (clinical), Geriatrics and Gerontology, Nursing homes, business, medicine.drug
Published
2006

16. P4–410: Steady–state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer's disease are not affected by co–administration of memantine

Author

Sandeep Athalye, Greg Sedek, Picard Frank, Françoise Pommier, Juanita Smith, Joshua R. Shua-Haim, and Gilbert Lefèvre

Subjects
Rivastigmine, biology, Epidemiology, business.industry, Health Policy, Memantine, Disease, Pharmacology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Pharmacokinetics, medicine, biology.protein, In patient, Neurology (clinical), Steady state (chemistry), Geriatrics and Gerontology, business, medicine.drug, Co administration, Cholinesterase
Abstract

Background and objective: It has been shown that combining memantine and a cholinesterase inhibitor, which each affect different neurotransmitter systems, may offer further improvements in efficacy over either treatment alone in patients with Alzheimer’s disease. The present study was conducted to determine if memantine has any effects on the steady-state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer’s disease.

Published
2006

17. Dextromethorphan HBr and quindine sulphate (Nuedexta) for the treatment of pseudobulbar affect (PBA) in an Alzheimer's disease patient residing in a nursing home: A Case Report

Author

Joshua Shua-Haim, Juanita Smith, and Patricia Brogan

Subjects
medicine.medical_specialty, Pseudobulbar affect, business.industry, Health Policy, Dextromethorphan hbr, Disease patient, General Medicine, medicine, Geriatrics and Gerontology, medicine.symptom, Psychiatry, business, Nursing homes, General Nursing
Published
2012

22. P1-377 Safety, tolerability, and caregiver's impressions of combination therapy with rivastigmine and memantine for the treatment of Alzheimer's disease

Author

Paul P. Lee, Sameer Patel, Suhas Patel, Mark D. Pass, Juanita Smith, and Joshua R. Shuan-Haim

Subjects
Rivastigmine, Aging, medicine.medical_specialty, Combination therapy, business.industry, General Neuroscience, Memantine, Safety tolerability, Disease, Internal medicine, medicine, Neurology (clinical), Geriatrics and Gerontology, business, Developmental Biology, medicine.drug
Published
2004

23. P1-045 A retrospective analysis of nursing home transfer rates for Alzheimer's disease patients residing in assisted living facilities treated with galantamine

Author

Juanita Smith, Sameer Patel, Suhas Patel, Joshua R. Shua-Haim, and Mark D. Pass

Subjects
Gerontology, Aging, business.industry, General Neuroscience, Assisted Living Facility, Disease, Galantamine, medicine, Retrospective analysis, Neurology (clinical), Geriatrics and Gerontology, Nursing homes, business, Developmental Biology, medicine.drug
Published
2004

24. P1-337 Safety and tolerability of high dose donepezil in patients with Alzheimer's disease. A preliminary report of a pilot study

Author

Suhas Patel, Juanita Smith, Joshua R. Shua-Haim, Mark D. Pass, Pritesh Patel, Sameer Patel, and Paul P. Lee

Subjects
Aging, medicine.medical_specialty, business.industry, General Neuroscience, Disease, Tolerability, Preliminary report, Internal medicine, medicine, In patient, Neurology (clinical), Geriatrics and Gerontology, Donepezil, business, Developmental Biology, medicine.drug
Published
2004

25. P1-385 A head study of donepezil, rivastigmine, and galantamine for the treatment of Alzheimer's disease: safety, tolerability, clinical and caregiver impressions after 9 months of treatment

Author

Joshua R. Shua-Haim, Suhas Patel, Paul P. Lee, Pritesh Patel, Sameer Patel, Mark D. Pass, and Juanita Smith

Subjects
Rivastigmine, Aging, medicine.medical_specialty, business.industry, General Neuroscience, Safety tolerability, Disease, Internal medicine, Galantamine, Medicine, Head (vessel), Neurology (clinical), Geriatrics and Gerontology, business, Donepezil, Developmental Biology, medicine.drug
Published
2004

28. P1-308 Galantamine in the treatment of moderate to advanced Alzheimer's disease: clinical and pharmacoeconomic outcomes in the assisted living environment

Author

Joshua R. Shua-Haim, Suhas Patel, Juanita Smith, Sameer Patel, and Mark D. Pass

Subjects
Aging, medicine.medical_specialty, business.industry, General Neuroscience, Disease, Galantamine, Medicine, Neurology (clinical), Geriatrics and Gerontology, business, Psychiatry, Developmental Biology, Assisted living, medicine.drug
Published
2004

32. Big differences in little people

Author

Juanita Smith

Subjects
Humans, Infant, Female, General Medicine, Growth, General Nursing, Pediatric Nursing
Published
1988

33. Brand Whitlock: His Life and His Fiction

Author

Ernest Warren Baughman, George Warren Arms, Charles Burnet Judah, Kytle, Juanita Smith, Ernest Warren Baughman, George Warren Arms, Charles Burnet Judah, and Kytle, Juanita Smith

Subjects
English Language and Literature
Abstract

Brand Whitlock lived a varied and active life during an extremely complex period of our history. The threads have not, by any means, been disentangled, but there are some generalizations which may be made. Even though they offer the difficulties that all generalizations do, the following tentative conclusions may be of some help in fitting the man into his time; they may be used, perhaps, as a framework on which to hang the complexities.

Published
1958

34. Brand Whitlock: His Life and His Fiction

Author

Kytle, Juanita Smith

Subjects
English Language and Literature
Abstract

Brand Whitlock lived a varied and active life during an extremely complex period of our history. The threads have not, by any means, been disentangled, but there are some generalizations which may be made. Even though they offer the difficulties that all generalizations do, the following tentative conclusions may be of some help in fitting the man into his time; they may be used, perhaps, as a framework on which to hang the complexities.

Published
1958

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