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Return to work (RTW) after a coronary event remains a major concern. This systematic review and meta-analysis of prospective studies published between January 1988 and August 2020, aim to evaluate the prevalence of RTW after a coronary event (myocardial infarction, acute coronary syndrome, angina pectoris) and to assess the determinants of RTW (such as follow-up duration, date of recruitment, country, gender, occupational factors, etc.). PRISMA and MOOSE guidelines were followed. Study quality was assessed using the Newcastle–Ottawa Scale. Random-effects models were carried out to determine pooled prevalence estimates and 95% confident interval. A total of 43 prospective studies (34,964 patients) were investigated. RTW overall random effects pooled prevalence was estimated at 81.1% [95% CI 75.8–85.8]. Country, year of implementation or gender did not significantly modify the prevalence estimates. Lower level of education and degraded left ventricular ejection fraction decreased RTW prevalence estimates (respectively, 76.1% vs 85.6% and 65.3% vs 77.8%). RTW prevalence estimates were higher for white-collars (81.2% vs 65.0% for blue-collars) and people with low physical workload (78.3% vs 64.1% for elevated physical workload).Occupational physical constraints seem to have a negative role in RTW while psycho-logical factors at work are insufficiently investigated. A better understanding of the real-life working conditions influencing RTW would be useful to maintain coronary patients in the labor market.

Contexte Les biocides de la famille des isothiazolinones sont bien connus pour etre responsables de dermatites allergiques de contact lors d’un usage essentiellement personnel (cosmetiques) mais aussi professionnel, notamment chez les peintres. Recemment, quelques cas associant des dermatoses et des troubles respiratoires ont ete decrits uniquement chez des personnes exposees au methylisothiazolinone lors d’activite de bricolage en dehors d’un contexte professionnel. Objectif Decrire le cas d’un travailleur effectuant des travaux de renovation expose a plusieurs types de produits, presentant une toux persistante resistante aux traitements entrepris associee a un eczema. Methode Des pricks-tests, des patch-tests specifiques ainsi des explorations fonctionnelles respiratoires ont ete realises. Resultats Les tests realises confirment une sensibilisation a la methylisothiazolinone et au melange methylisothiazolinone/chloromethylisothiazolinone et une reactivite bronchique. La disparition des symptomes n’est obtenue qu’apres la non-exposition aux produits manipules. Conclusion Le cas de ce patient argumente la necessite d’une labellisation des produits professionnels contenant ce type de biocide comme potentiellement allergisant pour la peau et irritatif pour l’appareil respiratoire.