29 results on '"Junya Ota"'
Search Results
2. Phenotypic variability of RP1-related inherited retinal dystrophy associated with the c.5797 C > T (p.Arg1933*) variant in the Japanese population
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Keigo Natsume, Taro Kominami, Kensuke Goto, Yoshito Koyanagi, Taiga Inooka, Junya Ota, Kenichi Kawano, Kazuhisa Yamada, Daishi Okuda, Kenya Yuki, Koji M. Nishiguchi, and Hiroaki Ushida
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Retinitis pigmentosa ,Cone-rod dystrophy ,Macular dystrophy ,Medicine ,Science - Abstract
Abstract The phenotypes of RP1-related inherited retinal dystrophies (RP1-IRD), causing autosomal dominant (AD) and autosomal recessive (AR) diseases, vary depending on specific RP1 variants. A common nonsense mutation near the C-terminus, c.5797 C > T (p.Arg1933*), is associated with RP1-IRD, but the exact role of this mutation in genotype-phenotype correlation remains unclear. In this study, we retrospectively analyzed patients with RP1-IRD (N = 42) from a single center in Japan. AR RP1-IRD patients with the c.5797 C > T mutation (N = 14) mostly displayed macular dystrophy but rarely retinitis pigmentosa or cone-rod dystrophy. Conversely, AR RP1-IRD patients without the c.5797 C > T mutation, including those with other pathogenic RP1 variants, were mostly diagnosed with severe retinitis pigmentosa. Full-field electroretinograms were significantly better in patients homozygous or compound heterozygous for the c.5797 C > T mutation than in those without this mutation, corresponding to their milder phenotypes. Clinical tests also revealed a slower onset of age and a better mean deviation value with the static visual field in AR RP1-IRD patients with the c.5797 C > T mutation compared to those without. Therefore, the presence of c.5797 C > T may partly account for the phenotypic variety of RP1-IRD and may yield milder phenotypes. These findings may be useful for predicting the prognosis of RP1-IRD patients.
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- 2024
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3. Fundus autofluorescence features specific for EYS-associated retinitis pigmentosa.
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Taro Kominami, Tien-En Tan, Hiroaki Ushida, Kanika Jain, Kensuke Goto, Yasmin M Bylstra, Ai Fujita Sajiki, Ranjana S Mathur, Junya Ota, Weng Khong Lim, Koji M Nishiguchi, and Beau J Fenner
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Medicine ,Science - Abstract
PurposeTo assess the utility of fundus autofluorescence (FAF) patterns for predicting the EYS genotype in retinitis pigmentosa (RP) patients.MethodsThis retrospective, multi-institutional study analyzed FAF images from 200 RP patients (74 with EYS and 126 without EYS) from Singapore and Japan. Seven FAF patterns including the infinity sign and a broad banded hyper-autofluorescent leading edge were evaluated for their association with the EYS genotype.ResultsThe infinity sign and broad banded hyperautofluorescent leading edge occurred more frequently in EYS eyes (p = 0.0014 and p = 0.036 respectively). Logistic regression analysis showed that the infinity sign was predictive of EYS (p = 0.003). The combined FAF parameters predicted EYS with a specificity of 95.20%, sensitivity of 25.68% and accuracy of 69.50%, with a cut-off value 0.5 based on the probability of seven FAF parameters.ConclusionsIn this multinational cohort study of patients with RP, we demonstrated that specific FAF patterns, particularly the infinity sign, have clinical utility in identifying patients with EYS-associated disease. These findings may be useful for clinicians and geneticists when genotyping patients with RP, and may also enhance our understanding of underlying pathophysiology of EYS-associated RP, which is a prevalent cause of RP in Asia and elsewhere.
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- 2025
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4. Acute acquired comitant esotropia associated with Lhermitte–Duclos disease: a case report
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Junya Ota, Ryo Ando, Hiroaki Motegi, Hirokazu Sugino, Tomoko Mitsuhashi, and Susumu Ishida
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Acute acquired comitant esotropia ,Lhermitte–Duclos disease ,Papilledema ,Hydrocephalus ,A case report ,Medicine - Abstract
Abstract Background Acute acquired comitant esotropia caused by prolonged near work, such as the use of digital devices, has been frequently reported in recent years. However, intracranial examination is necessary even for patients with nonparalytic comitant esotropia. Lhermitte–Duclos disease is a rare tumor that grows in layers in the cerebellum. Among those with this disease, cases of esotropia have been reported due to abduction limitation of the eye, but there have been no reports of comitant esotropia. Here, we report the case of a young woman with acute acquired comitant esotropia who was found to have Lhermitte–Duclos disease. Case presentation A 16-year-old Japanese female patient, whose ethnicity was Asian, was referred to our hospital for acute acquired comitant esotropia. Fundus examination revealed papilledema in both eyes, and magnetic resonance imaging of the head revealed a cerebellar tumor in the right cerebellum with obstructive hydrocephalus. She underwent partial tumor resection, and a histopathological diagnosis of Lhermitte–Duclos disease was obtained. However, comitant esotropia status remained unchanged, and she underwent strabismus surgery. Finally, diplopia disappeared completely. Conclusion Neurological and intracranial imaging examinations are essential when acute acquired comitant esotropia is observed. Acute acquired comitant esotropia by Lhermitte–Duclos disease did not improve with partial tumor resection and required strabismus surgery, but good surgical results were obtained.
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- 2024
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5. Assessment of factors affecting flicker ERGs recorded with RETeval from data obtained from health checkup screening
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Taiga Inooka, Taro Kominami, Shunsuke Yasuda, Yoshito Koyanagi, Junya Ota, Satoshi Okado, Ryo Tomita, Yasuki Ito, Takeshi Iwase, Hiroko Terasaki, Koji M. Nishiguchi, and Shinji Ueno
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Medicine ,Science - Abstract
Purpose To determine the factors significantly associated with the amplitudes and implicit times of the flicker electroretinograms (ERGs) recorded with the RETeval system by analyzing the comprehensive data obtained during a health checkup screening. Methods Flicker ERGs were recorded with the RETeval system from 373 individuals who had a normal fundus and optical coherence tomography images. The sex, age, anthropometric, ophthalmologic, and hematologic data were collected from all participants who were 40- to 89-years-of-age. Univariable and multivariable linear mixed effects regression analyses were performed to identify factors that were significantly associated with the implicit times and amplitudes of the RETeval flicker ERGs. Results Univariable linear mixed effects regression analysis showed significant correlations between the implicit times and the best-corrected visual acuity, the age, the axial length, the blood sugar level, and the blood urea nitrogen level. Analyses by multivariable linear mixed effects regression identified that the axial length (β = 0.28), the age (β = 0.24), and the blood sugar level (β = 0.092) were three independent factors that were significantly correlated with the implicit times of the RETeval flicker ERGs. Univariable linear mixed effects regression analysis also showed significant correlations between the amplitudes of the RETeval flicker ERGs and the age, the platelet count, and the creatinine level. Multivariable linear mixed effects regression models identified the age (β = -0.092), the platelet count (β = 0.099), and the creatinine level (β = -0.12) as three independent factors that were significantly correlated with the amplitudes of the RETeval flicker ERGs. However, the smoking habits, body mass index, and the blood pressure were not significantly correlated with either the implicit times or amplitudes of the RETeval flicker ERGs. Conclusions Our results indicate that the age and some ophthalmologic and hematologic findings but not the anthropometric findings were significantly associated with the implicit times and amplitudes of the RETeval flicker ERGs. Thus, clinicians should remember these factors when analyzing the RETeval flicker ERGs.
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- 2023
6. Disease-specific variant interpretation highlighted the genetic findings in 2325 Japanese patients with retinitis pigmentosa and allied diseases.
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Kensuke Goto, Yoshito Koyanagi, Masato Akiyama, Yusuke Murakami, Masatoshi Fukushima, Kohta Fujiwara, Hanae Iijima, Mitsuyo Yamaguchi, Mikiko Endo, Kazuki Hashimoto, Masataka Ishizu, Toshiaki Hirakata, Kei Mizobuchi, Masakazu Takayama, Junya Ota, Ai Fujita Sajiki, Taro Kominami, Hiroaki Ushida, Kosuke Fujita, and Hiroki Kaneko
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Background As gene-specific therapy for inherited retinal dystrophy (IRD) advances, unified variant interpretation across institutes is becoming increasingly important. This study aims to update the genetic findings of 86 retinitis pigmentosa (RP)-related genes in a large number of Japanese patients with RP by applying the standardised variant interpretation guidelines for Japanese patients with IRD (J-IRD-VI guidelines) built upon the American College of Medical Genetics and Genomics and the Association for Molecular Pathology rules, and assess the contribution of these genes in RP–allied diseases. Methods We assessed 2325 probands with RP (n=2155, including n=1204 sequenced previously with the same sequencing panel) and allied diseases (n=170, newly analysed), including Usher syndrome, Leber congenital amaurosis and cone-rod dystrophy (CRD). Target sequencing using a panel of 86 genes was performed. The variants were interpreted according to the J-IRD-VI guidelines. Results A total of 3564 variants were detected, of which 524 variants were interpreted as pathogenic or likely pathogenic. Among these 524 variants, 280 (53.4%) had been either undetected or interpreted as variants of unknown significance or benign variants in our earlier study of 1204 patients with RP. This led to a genetic diagnostic rate in 38.6% of patients with RP, with EYS accounting for 46.7% of the genetically solved patients, showing a 9% increase in diagnostic rate from our earlier study. The genetic diagnostic rate for patients with CRD was 28.2%, with RP-related genes significantly contributing over other allied diseases. Conclusion A large-scale genetic analysis using the J-IRDVI guidelines highlighted the population-specific genetic findings for Japanese patients with IRD; these findings serve as a foundation for the clinical application of gene-specific therapies. [ABSTRACT FROM AUTHOR]
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- 2024
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7. Assessment of factors affecting flicker ERGs recorded with RETeval from data obtained from health checkup screening
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Taiga Inooka, Taro Kominami, Shunsuke Yasuda, Yoshito Koyanagi, Junya Ota, Satoshi Okado, Yasuki Ito, Hiroko Terasaki, Koji M. Nishiguchi, and Shinji Ueno
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genetic structures ,sense organs ,eye diseases - Abstract
The purpose of this study was to determine the ocular, sex- and age-specific, anthropometric, and hematologic factors that affect the implicit times and amplitudes of the flicker ERGs recorded with the RETeval system from individuals 40- to 89-years-of-age. Flicker ERGs were recorded with the RETeval system from 330 individuals who had normal fundus and OCT images. Univariate and multivariate regression analyses were performed to identify factors associated with the implicit times and amplitudes of the RETeval flicker ERGs. Univariate regression analyses showed significant correlations between the implicit times and the BCVA, age, axial length, blood sugar level, and BUN in both eyes. Multivariate regression analyses identified age and axial length as two independent factors that were significantly correlated with the implicit times of the RETeval flicker ERGs. Univariate regression analyses also showed significant correlations between the amplitudes and age, platelet count, HDL level, and creatinine level in both eyes. However, smoking habits, body mass index, and blood pressure were not correlated with the RETeval flicker ERGs. We conclude that age and some ophthalmologic and hematologic findings except for anthropometric findings were suggested to significantly affect the measurements of the RETeval flicker ERGs.
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- 2022
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8. Sensitivity Analysis of Drivetrain Oscillations in Electric Vehicles
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Markus Lienkamp, Junya Ota, and Matthias Foerth
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Physics ,Acoustics ,Modal analysis ,Drivetrain ,Sensitivity (control systems) - Abstract
The increase of electric mobility is leading to new drivetrain designs in vehicle development. A common problem in electric drivetrains are torsional oscillations caused by elastic components. These components are wheel shafts, tires and bushings. A common problem, its sensitivity to parameter variation has not yet been fully investigated. The objective of this study is to quantify the sensitivity of oscillation frequency, damping and coupling between components with respect to key drivetrain parameters. A parameter space is investigated using Monte-Carlo sampling. A linear state space model is parameterized for each sample. Modal analysis permits the analysis of oscillation frequency, damping and coupling between components using the state variables. Subsequently, a Gaussian mixture model clusters the resulting data to form mode groups. Finally, linear regressions quantify the sensitivities. The results show oscillation damping can be increased by stiff wheel shafts. Decoupling of components in oscillation modes is mainly achieved by separating the oscillation frequencies of the different modes.
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- 2018
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9. Investigation of serum antibody titers for periodontopathic bacteria in diabetic patients
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Junko Tagomori, Mayako Akamatsu, Satoru Morikawa, Hiroshi Ito, Junya Ota, Taneaki Nakagawa, Shunsuke Kasai, Yoshifumi Saisho, Toshihide Kawai, Chie Fukaya, and Toru Eguchi
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Titer ,business.industry ,Immunology ,Medicine ,business ,Periodontopathic bacteria ,Serum antibody - Published
- 2015
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10. Antibacterial activity of sitafloxacin against pathogens in artificial biofilms
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Eitoyo Kokubu, Chie Fukaya, Junya Ota, Shunsuke Kasai, Takumi Oishi, Kazuyuki Ishihara, Taneaki Nakagawa, and Atsushi Saito
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Sitafloxacin ,Chemistry ,medicine ,Biofilm ,Antibacterial activity ,medicine.drug ,Microbiology - Published
- 2015
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11. Relationship between periodontal disease and diabetic complications
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Satoru Morikawa, Mayako Akamatsu, Shunsuke Kasai, Toshihide Kawai, Chie Fukaya, Hiroshi Ito, Yoshifumi Saisho, Junya Ota, Taneaki Nakagawa, Toru Eguchi, and Junko Tagomori
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medicine.medical_specialty ,Periodontal disease ,business.industry ,Internal medicine ,medicine ,business - Published
- 2013
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12. Effects of plaque removal with SonicareⓇDiamondClean
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Soh Sato, Chie Fukaya, Taneaki Nakagawa, Tomoko Takashio, Junya Ota, Takuya Ueno, Shunsuke Kasai, Ryohei Nakayama, and Yuko Morozumi
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business.industry ,Plaque removal ,Medicine ,business - Published
- 2013
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13. Prevalence and risk factors for peri-implant diseases in Japanese adult dental patients
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Junya Ota, Yasuo Takeuchi, Tadashi Yasuda, Matsuo Yamamoto, Shinji Deguchi, Hirokazu Arita, Toshirou Hidaka, Takehiko Kubota, Hiromasa Yoshie, Yasushi Furuichi, Keita Inokuchi, Yorimasa Ogata, Takashi Yaegashi, Hisao Araki, Takashi Takiguchi, Yohei Nakayama, Kenji Nemoto, Keiko Yamaki, Yoshiaki Hasegawa, Keita Kubokawa, Takatoshi Ito, Etsuko Matsuzaki, Atsushi Saito, Noriharu Ikumi, Kazuhiro Gomi, Yuichi Ishihara, Hideki Kogai, Ryuji Sakagami, Toshiro Kodama, Yuichi Izumi, Toshiaki Yoshino, Kitetsu Shin, Yukie Takagi, Tokuya Onitsuka, Takenori Nozaki, Takashi Kado, Kazuyuki Noguchi, Daisuke Sasaki, Tetsuya Nishida, Mikimoto Kanazashi, Yukihiko Aoyama, Junichi Tatsumi, Taneaki Nakagawa, Toshiaki Shibutani, Shuichi Sato, Naritoshi Matsubara, Nobuo Yoshinari, Shinya Murakami, Taichi Ito, Tetsushi Hirose, Maki Tanaka, and Toshinaga Sase
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0301 basic medicine ,Adult ,Male ,Peri ,Dentistry ,Disease ,Plaque control ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Japan ,Risk Factors ,medicine ,Mucositis ,Prevalence ,Humans ,General Dentistry ,Aged ,Periodontitis ,Aged, 80 and over ,business.industry ,030206 dentistry ,Middle Aged ,medicine.disease ,Peri-Implantitis ,Dental patients ,030104 developmental biology ,Cross-Sectional Studies ,Multicenter study ,Female ,Implant ,business - Abstract
We investigated the prevalences and risk factors for peri-implant diseases in Japanese adult dental patients attending a follow-up visit at dental hospitals or clinics as part of their maintenance program. This cross-sectional multicenter study enrolled patients with dental implants who attended regular check-ups as part of a periodontal maintenance program during the period from October 2012 through September 2013. Patients with implants with at least 3 years of loading time were included in the study. The condition of peri-implant tissue was examined and classified into the following categories: healthy, peri-implant mucositis, and peri-implantitis. Patients were also evaluated for implant risk factors. A total of 267 patients (110 men, 157 women; mean age: 62.5 ± 10.7 years) were analyzed. The prevalence of patient-based peri-implant mucositis was 33.3% (n = 89), and the prevalence of peri-implantitis was 9.7% (n = 26). Poor oral hygiene and a history of periodontitis were strong risk factors for peri-implant disease. The present prevalences were lower than those previously reported. The quality of periodontal therapy before and after implant installation and patient compliance and motivation, as indicated by plaque control level, appear to be important in maintaining peri-implant tissue health.
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- 2016
14. Model Based Development of Future Small Electric Vehicle by Modelica
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Yutaka Hirano, Shintaro Inoue, and Junya Ota
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Vehicle dynamics ,Engineering ,business.product_category ,business.industry ,Electric vehicle ,Model-based design ,Control engineering ,Workload ,Energy consumption ,business ,Modelica ,Automotive engineering ,Yaw moment - Abstract
For future low carbon mobility society, new-type small electric vehicles (EVs) are developed actively in recent period. To reduce the energy consumption in various actual driving conditions, considering overall running resistance from tire characteristics, mechanical losses and electrical losses is necessary. In this paper, modelbased development of system performance of a new EV is described. Full vehicle model considering both vehicle dynamics and energy consumption was developed using Modelica. Research for both structure and specification of components of the vehicle and also of the control were performed to find the solution to satisfy both energy consumption and vehicle dynamics by using the full vehicle model. Finally trade-off between vehicle stability and energy consumption and also between driver workload and energy consumption by using direct yaw moment control was indicated.
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- 2015
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15. Model based performance development of a future small electric vehicle using Modelica
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Junya Ota, Yutaka Hirano, and Shintaro Inoue
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Vehicle dynamics ,Engineering ,business.product_category ,business.industry ,Electric vehicle ,Stability (learning theory) ,Control engineering ,Energy consumption ,business ,Yaw moment ,Automotive engineering ,Modelica - Abstract
For future low carbon mobility society, new-type small electric vehicles (EVs) are developed actively in recent period. To reduce the energy consumption in various actual driving conditions, considering overall running resistance from tire characteristics, mechanical losses and electrical losses is necessary. Also, to cope with reduced stability against external disturbances because of the light weight, it is necessary to apply vehicle dynamics control utilizing direct yaw moment control. In this paper, model-based performance development of a new electric vehicle is described. Full vehicle model considering both vehicle dynamics and energy consumption was developed using Modelica. Research for both structure and specification of components of the vehicle and also of the control were performed to find the solution to satisfy both energy consumption and vehicle dynamics by using the full vehicle model.
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- 2015
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16. Reduction of Turbine Bypass Blow off Steam by Lowering the Minimum Load of No. 4 Boiler
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Junya Ota
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Engineering ,business.industry ,Control theory ,Mechanical Engineering ,Media Technology ,Boiler (power generation) ,General Materials Science ,General Chemistry ,business ,Turbine ,Automotive engineering - Abstract
当工場の4号ボイラー(循環流動層式)は1995年に3号ボイラー(重油焚き)から燃料転換のため稼動した。4号ボイラーの最大蒸発量は120t/hで4台のマシンが稼動していた時は,95t/h~120t/hで運転していた。2002年より大型マシン1台の稼動日数が減少し,2003年1月より休止したため負荷は75t/h~96t/hとなった。低負荷運転では,火炉底部の燃焼空気吹き込み口のノズルが閉塞してくる。このため,最低負荷を75t/hにして運転していた。大型マシン休止後,その他のマシン休転整備時には工場使用電力が減少し,ボイラー負荷が75t/hでは,発電電力が多すぎて電力会社へ逆送となるため,タービンバイパスで大気放出する運転状態が発生してきた。大気放出を減少させるためには,ボイラーの負荷をさらに下げる必要があり,そのため燃焼用空気吹き込み口であるグリッドノズルの改造が必要となった。グリッドノズルの形状をピッグテイルノズルからアローヘッドノズルに変更することによりノズル穴にベッド材の侵入を防ぐようにし,低負荷運転でもノズルが閉塞しないように対策した。現在の最低負荷は62t/hまで下がっており,計算による閉塞率は23%と問題ない状況であり大気放出はせずに運転できている。ボイラーの低負荷対策による大気放出削減量は約600t/月となっている。
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- 2004
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17. Model-based Development of Future Small EVs using Modelica
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Junya Ota, Yutaka Hirano, and Shintaro Inoue
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Engineering ,business.product_category ,business.industry ,Rolling resistance ,Control engineering ,Aerodynamics ,Energy consumption ,Modelica ,Automotive engineering ,Vehicle dynamics ,Control system ,Model-based design ,Electric vehicle ,business - Abstract
To cope with demands for future low carbon society, development of new-type small electric vehicles (EVs) becomes very active. To reduce the energy consumption in various actual driving conditions, considering overall running resistance such as aerodynamic resistance, tire rolling resistance including cornering drag, mechanical and electrical losses, etc. will be necessary. On the other hand, to cope with reduced stability against external disturbances such as side wind because of the light weight, it was clarified that additional control of direct yaw moment is effective. In this paper, model-based development of a new electric vehicle using Modelica is described. Full vehicle model considering both vehicle dynamics and energy consumption was developed and utilized to investigate the best possible solutions for both basic design of the vehicle and design of the control system.
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- 2014
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18. Influence of anisotropic diffusion of Ga and Al atoms during AlGaAs growth for periodically-inverted AlGaAs waveguides
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Shigeki Yoshida, Tomonori Matsushita, Takashi Kondo, and Junya Ota
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Condensed Matter::Quantum Gases ,Materials science ,Condensed matter physics ,Anisotropic diffusion ,business.industry ,Atomic force microscopy ,Physics::Optics ,Cathodoluminescence ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,Waveguide (optics) ,Gallium arsenide ,chemistry.chemical_compound ,Optics ,chemistry ,Modulation ,Physics::Atomic and Molecular Clusters ,Physics::Atomic Physics ,Diffusion (business) ,business ,Spectroscopy - Abstract
We have investigated a quasi-phase-matching AlGaAs waveguide using cathodoluminescence spectroscopy and atomic force microscopy. We found that the anisotropic diffusion of Al/Ga atoms causes Al-composition modulation as well as interface corrugations.
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- 2012
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19. Periodic modulation of Al composition in a periodically-inverted AlGaAs waveguide
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Kazuhiro Iwamoto, Junya Ota, Tomonori Matsushita, and Takashi Kondo
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Waveguide (electromagnetism) ,Materials science ,Anisotropic diffusion ,business.industry ,Physics::Optics ,Cathodoluminescence ,Nonlinear optical crystal ,Epitaxy ,Modulation ,Physics::Atomic and Molecular Clusters ,Optoelectronics ,business ,Spectroscopy ,Layer (electronics) - Abstract
We have investigated a periodically-inverted Al0:40Ga0:60As layer in a quasi-phase-matching AlGaAs waveguide using cathodoluminescence spectroscopy, and found that Al-composition modulation is formed by the anisotropic diffusion of Al/Ga atoms during the molecular-beam epitaxy growth process.
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- 2011
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20. Impact of Photoelastic Effect on Phase-Matching Wavelengths in Periodically-Inverted AlGaAs Waveguides
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Koji Amazutsumi, Junya Ota, Tomonori Matsushita, and Takashi Kondo
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Wavelength ,Materials science ,Optics ,business.industry ,law ,Semiconductor materials ,Physical vapor deposition ,Optoelectronics ,business ,Waveguide ,Phase matching ,law.invention - Abstract
We have shown that photoelastic effect alters the phase-matching wavelengths of Type-I and Type-II quasi-phase-matched second-harmonic generation in a periodically-inverted AlGaAs waveguide through the uniaxial strain in the pseudomorphic AlGaAs layers.
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- 2011
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21. Quasi-Phase-Matched Difference Frequency Generation at 3.4 μm in High-Quality GaAs/AlGaAs Waveguides
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Junya Ota, Ikuma Ohta, Kaori Hanashima, Tomonori Matsushita, and Takeshi Kondo
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Frequency generation ,Quality (physics) ,Materials science ,business.industry ,Phase (waves) ,Optoelectronics ,business ,Gaas algaas - Published
- 2010
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22. Quasi-Phase-Matched Second-Harmonic Generation in High-Quarity AlGaAs Waveguides Pumped at 1.55 μm
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Junya Ota, Tomonori Matsushita, Takashi Kondo, and Ikuma Ohta
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Optics ,Materials science ,Ridge waveguides ,business.industry ,Wavelength-division multiplexing ,Phase (waves) ,Physics::Optics ,Second-harmonic generation ,Nonlinear optics ,Optoelectronics ,Wavelength conversion ,business ,Nonlinear optical crystal - Abstract
We have fabricated high-quality periodically-inverted AlGaAs ridge waveguides by introducing the low temperature MBE growth process, and achieved relatively low propagation losses and highly efficient quasi-phased matched second-harmonic generation pumped at 1.55 um.
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- 2010
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23. Wavelength Conversion in Semiconductor Waveguiding Devices
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Tae Woong Kim, Ikuma Ohta, Hiroshi Ishikawa, Takashi Kondo, Junya Ota, Kaori Hanashima, Kengo Ban, and Tomonori Matsushita
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Materials science ,Birefringence ,business.industry ,Physics::Optics ,Nonlinear optics ,Wavelength conversion ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,law.invention ,Nonlinear system ,Optical nonlinearity ,Optics ,Semiconductor ,law ,Optoelectronics ,Integrated optics ,business ,Nonlinear Sciences::Pattern Formation and Solitons ,Waveguide - Abstract
Wavelength conversion via quadratic optical nonlinearity in AlGaAs-based waveguiding devices will be presented. Efficient quasi-phase-matched nonlinear conversions are demonstrated in periodically inverted AlGaAs waveguides. A novel device utilizing birefringence in thin high-index-contrast waveguide is proposed.
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- 2009
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24. Quasi-Phase-Matched Second-Harmonic Generation in AlGaAs Waveguides Pumped at 1.5μm
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Junya Ota, Tomonori Matsushita, W. Narita, Ikuma Ohta, and Takashi Kondo
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Materials science ,business.industry ,Phase (waves) ,Second-harmonic generation ,Optoelectronics ,business - Published
- 2008
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25. Prevalence and risk factors for peri-implant diseases in Japanese adult dental patients.
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Yorimasa Ogata, Yohei Nakayama, Junichi Tatsumi, Takehiko Kubota, Shuichi Sato, Tetsuya Nishida, Yasuo Takeuchi, Tokuya Onitsuka, Ryuji Sakagami, Takenori Nozaki, Shinya Murakami, Naritoshi Matsubara, Maki Tanaka, Toshiaki Yoshino, Junya Ota, Taneaki Nakagawa, Yuichi Ishihara, Taichi Ito, Atsushi Saito, and Keiko Yamaki
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DENTAL implant complications ,DENTAL care ,PERIODONTICS ,MUCOSITIS ,DENTAL plaque ,PERIODONTITIS ,DISEASE prevalence ,CROSS-sectional method - Abstract
We investigated the prevalences and risk factors for peri-implant diseases in Japanese adult dental patients attending a follow-up visit at dental hospitals or clinics as part of their maintenance program. This cross-sectional multicenter study enrolled patients with dental implants who attended regular check-ups as part of a periodontal maintenance program during the period from October 2012 through September 2013. Patients with implants with at least 3 years of loading time were included in the study. The condition of peri-implant tissue was examined and classified into the following categories: healthy, peri-implant mucositis, and peri-implantitis. Patients were also evaluated for implant risk factors. A total of 267 patients (110 men, 157 women; mean age: 62.5 ± 10.7 years) were analyzed. The prevalence of patient-based peri-implant mucositis was 33.3% (n = 89), and the prevalence of peri-implantitis was 9.7% (n = 26). Poor oral hygiene and a history of periodontitis were strong risk factors for peri-implant disease. The present prevalences were lower than those previously reported. The quality of periodontal therapy before and after implant installation and patient compliance and motivation, as indicated by plaque control level, appear to be important in maintaining peri-implant tissue health. [ABSTRACT FROM AUTHOR]
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- 2017
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26. Extremely long carrier lifetime at intermediate states in wall-inserted type II quantum dot absorbers
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Junya Ota, Yasuhiko Takeda, Naoya Miyashita, Kazutaka Nishikawa, Yoshitaka Okada, and Daisuke Sato
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Materials science ,business.industry ,General Physics and Astronomy ,Electron ,Carrier lifetime ,Gallium arsenide ,chemistry.chemical_compound ,chemistry ,Quantum dot ,Excited state ,Valence band ,Optoelectronics ,Spontaneous emission ,Wall thickness ,business - Abstract
To realize highly efficient intermediate-band solar cells (IB-SCs), a long lifetime of photo-generated carriers in the IB is essential. We propose a new concept for this purpose based on IB absorbers using quantum-dots (QDs). By inserting potential walls between QDs and barriers that form a type II band alignment, electrons in the IB and holes in the valence band are farther separated compared to those in a conventional type II QD material, leading to significant reduction of radiative recombination. We designed a concrete structure using InAs QDs, GaAs1−xSbx barriers, and GaAs walls to find the suitable GaAs wall thickness and Sb content being 2 nm and x = 0.18, respectively, and demonstrated a lifetime of electrons excited to the IB as long as 220 ns.
- Published
- 2012
- Full Text
- View/download PDF
27. Extremely long carrier lifetime over 200 ns in GaAs wall-inserted type II InAs quantum dots
- Author
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Kazutaka Nishikawa, Yasuhiko Takeda, Junya Ota, Naoya Miyashita, Tomoyoshi Motohiro, Yoshitaka Okada, and Daisuke Sato
- Subjects
Photoluminescence ,Materials science ,Physics and Astronomy (miscellaneous) ,business.industry ,Electron ,Carrier lifetime ,Gallium arsenide ,chemistry.chemical_compound ,Semiconductor quantum dots ,chemistry ,Quantum dot ,Valence band ,Optoelectronics ,business ,Spectroscopy - Abstract
To realize highly efficient intermediate-band (IB) solar cells, long lifetime of photo-generated carriers in the IB is essential. For this purpose, we propose a concept for IB absorbers using GaAs wall-inserted type II InAs quantum-dots (QDs), in which electrons at the IB of the InAs QDs and holes in the valence band of the GaAsSb layers are farther separated compared to those in conventional type II QDs. We fabricated InAs/GaAs/GaAs0.82Sb0.18 type II QDs and performed time-resolved photoluminescence spectroscopy. The obtained lifetime was as long as 220 ns for electrons at the IB.
- Published
- 2012
- Full Text
- View/download PDF
28. Over 100 ns intrinsic radiative recombination lifetime in type II InAs/GaAs1−xSbx quantum dots
- Author
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Yasuhiko Takeda, Naoya Miyashita, Junya Ota, Kazutaka Nishikawa, Ken-ichi Yamanaka, Yoshitaka Okada, Daisuke Sato, and Tomoyoshi Motohiro
- Subjects
chemistry.chemical_compound ,Charge-carrier density ,Photoluminescence ,Chemistry ,Quantum dot ,General Physics and Astronomy ,Spontaneous emission ,Rate equation ,Atomic physics ,Intensity (heat transfer) ,Excitation ,Gallium arsenide - Abstract
We report very long intrinsic radiative recombination lifetime τrad in type II InAs quantum dots embedded in GaAs1−xSbx. The dependence of photoluminescence (PL) decay time τPL on both the Sb composition (x = 0–0.18) and excitation intensity (38–460 mW/cm2) was systematically investigated by time-resolved PL measurements with a time-correlated single-photon counting method. All PL decay curves exhibited non-exponential profiles, and τPL was strongly dependent on the excitation intensity. These properties were well explained by solving rate equations of carrier density with neglecting nonradiative process, in which τrad is inversely proportional to carrier density. The 18% Sb sample exhibited a τPL of over 100 ns under weak excitation, which is longer than twice the previously reported values. We evaluated the value of τrad in InAs/GaAs1−xSbx QDs relative to that in type I InAs/GaAs QDs based on an effective mass approximation and found that the observed extremely long τPL corresponds to τrad.
- Published
- 2012
- Full Text
- View/download PDF
29. Fabrication of Periodically-Inverted AlGaAs Waveguides for Quasi-Phase-Matched Wavelength Conversion at 1.55 µm
- Author
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Junya Ota, Takashi Kondo, Tomonori Matsushita, Wataru Narita, and Ikuma Ohta
- Subjects
Fabrication ,Materials science ,Physics and Astronomy (miscellaneous) ,business.industry ,Energy conversion efficiency ,General Engineering ,Phase (waves) ,General Physics and Astronomy ,Epitaxy ,law.invention ,Wavelength ,Optics ,law ,Chemical-mechanical planarization ,Optoelectronics ,business ,Waveguide ,Order of magnitude - Abstract
We have improved fabrication processes of periodically inverted AlGaAs waveguides for highly efficient quasi-phase-matched wavelength conversion. In order to reduce propagation losses in waveguiding devices fabricated based on sublattice reversal epitaxy, we have introduced template planarization by chemical mechanical polishing and low-temperature regrowth technique. Corrugations at the core/clad interface and the propagation loss at 1.55 µm has been reduced to 40 nm and 9 dB/cm, respectively. First-order quasi-phase-matched second-harmonic generation was demonstrated at 1.55 µm fundamental wavelength with a 1.47-mm-long device. Obtained internal conversion efficiency is 2.2%/W which is one order of magnitude lower than the theoretical value for an ideal lossless waveguide. A significant increase in the conversion efficiency is expected with a redesign of the device and further optimization of the fabrication processes.
- Published
- 2009
- Full Text
- View/download PDF
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