10 results on '"Köster, Lennart"'
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2. Mechanismen zur automatisierten Qualitätssicherung und Validierung der Daten in medizinischen Registern
- Author
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Köster, Lennart
- Subjects
610 Medical sciences Medicine ,600 Technology (Applied sciences) - Abstract
Seltene Erkrankungen sind aufgrund der geringen Fallzahlen eine Herausforderung für die klinische Forschung. Register stellen eines der Instrumente zur systematischen Dokumentation von Verläufen von seltenen Erkrankungen dar. Ihre Aussagekraft hängt stark von der Qualität der Daten ab und somit von Mechanismen, welche die Qualität absichern sollen. Für einen Verbund aus drei Registern (CERTAIN, CERTAIN-LI und KRhOKo) sollten die Maßnahmen zur Sicherung die Datenqualität auf der Basis von automatischen Mechanismen verbessert werden. Hierfür wurde ein allgemeines Vorgehen zur Verbesserung der Datenqualität auf Basis der Qualitätsindikatoren (QI) der TMF-Leitlinie zum adaptiven Management von Datenqualität in Kohortenstudien und Registern entwickelt. Dieses Vorgehen bündelt die 51 QI der Leitlinie in vier QI-Kategorien mit unterschiedlichen Ansatzpunkten zur Verbesserung der Datenqualität: Registerplanung, automatische Validierung, Report und Datenverifizierung. Anhand des allgemeinen Vorgehens kann eine Gewichtung der QI für die Berechnung des Gesamtscores der TMF-Leitlinie erfolgen. Diese stützt sich auf eine initial durchzuführende Analyse der QI der TMF-Leitlinie im Hinblick auf die Kriterien Anwendbarkeit, Implementierbarkeit und Aussagekraft. Auf Basis des Ergebnisses der QI-Analyse verbleiben nur die für das jeweilige Register relevanten QI, für die über eine Priorisierung der QI innerhalb der identifizierten QI-Kategorien die Gewichte bestimmt werden können. Das allgemeine Vorgehen wurde für die drei genannten Register vollständig für alle QI der Leitlinie durchgeführt und die Ergebnisse der QI-Analyse, der Priorisierung der QI und der Zuweisung der Gewichte wurden detailliert dargestellt. Die QI-Analyse umfasst alle QI der TMF-Leitlinie und bietet eine detaillierte Betrachtung der QI. Aus diesen Ergebnissen wurde eine QI-Empfehlung entwickelt, die das entwickelte Vorgehen allgemein für elektronische Register vereinfacht und eine beispielhafte Priorisierung der QI bereitstellt. Auf Basis der QI-Analyse für die drei Register wurden Software-Komponenten zur Verbesserung der Datenqualität in Form von generischen Java-Modulen für die QI der Kategorie „automatische Validierung“ entwickelt, diese in die drei Register eingefügt und als Teil der Maßnahmen zur Sicherung der Datenqualität während der Dateneingabe genutzt. Die hierfür entwickelten Konzepte und Implementierungen wurden allgemein gehalten, so dass eine Übertragbarkeit der Konzepte und Java-Module auf andere Register gegeben ist. Die Effektivität dieser neuen Software-Komponenten konnte durch die umfangreiche Auswertung der Datenqualität des Datenbestandes des CERTAIN-Registers im Rahmen dieser Dissertation bestätigt werden. Somit konnte hier ein allgemeines Vorgehen zur Verbesserung der Datenqualität in medizinischen Registern durch automatisierte Mechanismen sowie ein Beispiel einer konkreten Umsetzung dieses Vorgehens und der Mechanismen dargestellt werden. Die QI-Empfehlung und die Ergebnisse der QI-Analyse für die drei Register stehen für andere zur Verbesserung ihrer Datenqualität als Basis zur Verfügung. Gleiches gilt für die Konzepte der entwickelten Software-Komponenten.
- Published
- 2019
3. Architecture of a consent management suite and integration into IHE-based regional health information networks
- Author
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Köster Lennart, Birkle Markus, Heinze Oliver, and Bergh Björn
- Subjects
Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Abstract Background The University Hospital Heidelberg is implementing a Regional Health Information Network (RHIN) in the Rhine-Neckar-Region in order to establish a shared-care environment, which is based on established Health IT standards and in particular Integrating the Healthcare Enterprise (IHE). Similar to all other Electronic Health Record (EHR) and Personal Health Record (PHR) approaches the chosen Personal Electronic Health Record (PEHR) architecture relies on the patient's consent in order to share documents and medical data with other care delivery organizations, with the additional requirement that the German legislation explicitly demands a patients' opt-in and does not allow opt-out solutions. This creates two issues: firstly the current IHE consent profile does not address this approach properly and secondly none of the employed intra- and inter-institutional information systems, like almost all systems on the market, offers consent management solutions at all. Hence, the objective of our work is to develop and introduce an extensible architecture for creating, managing and querying patient consents in an IHE-based environment. Methods Based on the features offered by the IHE profile Basic Patient Privacy Consent (BPPC) and literature, the functionalities and components to meet the requirements of a centralized opt-in consent management solution compliant with German legislation have been analyzed. Two services have been developed and integrated into the Heidelberg PEHR. Results The standard-based Consent Management Suite consists of two services. The Consent Management Service is able to receive and store consent documents. It can receive queries concerning a dedicated patient consent, process it and return an answer. It represents a centralized policy enforcement point. The Consent Creator Service allows patients to create their consents electronically. Interfaces to a Master Patient Index (MPI) and a provider index allow to dynamically generate XACML-based policies which are stored in a CDA document to be transferred to the first service. Three workflows have to be considered to integrate the suite into the PEHR: recording the consent, publishing documents and viewing documents. Conclusions Our approach solves the consent issue when using IHE profiles for regional health information networks. It is highly interoperable due to the use of international standards and can hence be used in any other region to leverage consent issues and substantially promote the use of IHE for regional health information networks in general.
- Published
- 2011
- Full Text
- View/download PDF
4. The Deployment of Intelligent Local-Based Information Systems (ilbi): A Case Study of the European Football Championship 2008.
- Author
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Peters, Mike, Piazolo, Felix, Köster, Lennart, and Promberger, Kurt
- Subjects
INFORMATION resources management ,MOBILE communication systems ,TOURISTS ,RADIO frequency identification systems - Abstract
Together with other cities in Austria and Switzerland, the city of Innsbruck hosted the UEFA (Union of European Football Association) EURO 2008™. The European Football Championships is the world's third-largest sport event. During this event, the mobile information system ilbi (intelligent local-based information), was tested. ilbi provides on-site information for tourists, event visitors, and locals with the help of radio frequency identification technology. The case study presented in this article shows options and challenges when installing a radio frequency identification based mobile information system at destinations. Recent literature in the field of mobile information systems in destinations is reviewed, and the case study of ilbi is presented. The article concludes with recommendations for further initiatives in the field of mobile location orientated information systems. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF
5. Integrating data from multiple sources for data completeness in a web-based registry for pediatric renal transplantation - the CERTAIN Registry.
- Author
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Köster, Lennart, Krupka, Kai, Höcker, Britta, Rahmel, Axel, Samuel, Undine, Zanen, Wouter, Opelz, Gerhard, Süsal, Caner, Döhler, Bernd, Plotnicki, Lukasz, Kohl, Christian D., Knaup, Petra, and Tönshoff, Burkhard
- Subjects
DATA analysis ,MEDICAL registries ,HUMAN ecology ,POPULATION research ,DATA quality - Abstract
Patient registries are a useful tool to measure outcomes and compare the effectiveness of therapies in a specific patient population. High data quality and completeness are therefore advantageous for registry analysis. Data integration from multiple sources may increase completeness of the data. The pediatric renal transplantation registry CERTAIN identified Eurotransplant (ET) and the Collaborative Transplant Study (CTS) as possible partners for data exchange. Import and export interfaces with CTS and ET were implemented. All parties reached their projected goals and benefit from the exchange. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
6. Architecture of a consent management suite and integration into IHE-based Regional Health Information Networks.
- Author
-
Heinze, Oliver, Birkle, Markus, Köster, Lennart, and Bergh, Björn
- Abstract
Background: The University Hospital Heidelberg is implementing a Regional Health Information Network (RHIN) in the Rhine-Neckar-Region in order to establish a shared-care environment, which is based on established Health IT standards and in particular Integrating the Healthcare Enterprise (IHE). Similar to all other Electronic Health Record (EHR) and Personal Health Record (PHR) approaches the chosen Personal Electronic Health Record (PEHR) architecture relies on the patient's consent in order to share documents and medical data with other care delivery organizations, with the additional requirement that the German legislation explicitly demands a patients' opt-in and does not allow opt-out solutions. This creates two issues: firstly the current IHE consent profile does not address this approach properly and secondly none of the employed intra- and inter-institutional information systems, like almost all systems on the market, offers consent management solutions at all. Hence, the objective of our work is to develop and introduce an extensible architecture for creating, managing and querying patient consents in an IHE-based environment.Methods: Based on the features offered by the IHE profile Basic Patient Privacy Consent (BPPC) and literature, the functionalities and components to meet the requirements of a centralized opt-in consent management solution compliant with German legislation have been analyzed. Two services have been developed and integrated into the Heidelberg PEHR.Results: The standard-based Consent Management Suite consists of two services. The Consent Management Service is able to receive and store consent documents. It can receive queries concerning a dedicated patient consent, process it and return an answer. It represents a centralized policy enforcement point. The Consent Creator Service allows patients to create their consents electronically. Interfaces to a Master Patient Index (MPI) and a provider index allow to dynamically generate XACML-based policies which are stored in a CDA document to be transferred to the first service. Three workflows have to be considered to integrate the suite into the PEHR: recording the consent, publishing documents and viewing documents.Conclusions: Our approach solves the consent issue when using IHE profiles for regional health information networks. It is highly interoperable due to the use of international standards and can hence be used in any other region to leverage consent issues and substantially promote the use of IHE for regional health information networks in general. [ABSTRACT FROM AUTHOR]- Published
- 2011
- Full Text
- View/download PDF
7. Integrating data from multiple sources for data completeness in a web-based registry for pediatric renal transplantation--the CERTAIN Registry.
- Author
-
Köster L, Krupka K, Höcker B, Rahmel A, Samuel U, Zanen W, Opelz G, Süsal C, Döhler B, Plotnicki L, Kohl CD, Knaup P, and Tönshoff B
- Subjects
- Child, Preschool, Data Accuracy, Database Management Systems, Europe, Female, Humans, Infant, Information Storage and Retrieval methods, Kidney Transplantation classification, Male, Meaningful Use organization & administration, Software, Tissue Donors, Transplant Recipients, Electronic Health Records organization & administration, Internet organization & administration, Kidney Transplantation statistics & numerical data, Medical Record Linkage methods, Pediatrics organization & administration, Registries
- Abstract
Patient registries are a useful tool to measure outcomes and compare the effectiveness of therapies in a specific patient population. High data quality and completeness are therefore advantageous for registry analysis. Data integration from multiple sources may increase completeness of the data. The pediatric renal transplantation registry CERTAIN identified Eurotransplant (ET) and the Collaborative Transplant Study (CTS) as possible partners for data exchange. Import and export interfaces with CTS and ET were implemented. All parties reached their projected goals and benefit from the exchange.
- Published
- 2015
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