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1. Prediction models used in the progression of chronic kidney disease: A scoping review.

Author

David K E Lim, James H Boyd, Elizabeth Thomas, Aron Chakera, Sawitchaya Tippaya, Ashley Irish, Justin Manuel, Kim Betts, and Suzanne Robinson

Subjects
Medicine, Science
Abstract

ObjectiveTo provide a review of prediction models that have been used to measure clinical or pathological progression of chronic kidney disease (CKD).DesignScoping review.Data sourcesMedline, EMBASE, CINAHL and Scopus from the year 2011 to 17th February 2022.Study selectionAll English written studies that are published in peer-reviewed journals in any country, that developed at least a statistical or computational model that predicted the risk of CKD progression.Data extractionEligible studies for full text review were assessed on the methods that were used to predict the progression of CKD. The type of information extracted included: the author(s), title of article, year of publication, study dates, study location, number of participants, study design, predicted outcomes, type of prediction model, prediction variables used, validation assessment, limitations and implications.ResultsFrom 516 studies, 33 were included for full-text review. A qualitative analysis of the articles was compared following the extracted information. The study populations across the studies were heterogenous and data acquired by the studies were sourced from different levels and locations of healthcare systems. 31 studies implemented supervised models, and 2 studies included unsupervised models. Regardless of the model used, the predicted outcome included measurement of risk of progression towards end-stage kidney disease (ESKD) of related definitions, over given time intervals. However, there is a lack of reporting consistency on details of the development of their prediction models.ConclusionsResearchers are working towards producing an effective model to provide key insights into the progression of CKD. This review found that cox regression modelling was predominantly used among the small number of studies in the review. This made it difficult to perform a comparison between ML algorithms, more so when different validation methods were used in different cohort types. There needs to be increased investment in a more consistent and reproducible approach for future studies looking to develop risk prediction models for CKD progression.

Published
2022
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2. Double-beta decay of $$^{130}\hbox {Te}$$ 130Te to the first $$0^+$$ 0+ excited state of $$^{130}\hbox {Xe}$$ 130Xe with CUORE-0

Author

C. Alduino, K. Alfonso, D. R. Artusa, F. T. Avignone III, O. Azzolini, T. I. Banks, G. Bari, J. W. Beeman, F. Bellini, A. Bersani, M. Biassoni, C. Brofferio, C. Bucci, A. Camacho, A. Caminata, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Carbone, L. Cardani, P. Carniti, N. Casali, L. Cassina, D. Chiesa, N. Chott, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, J. S. Cushman, A. D’Addabbo, I. Dafinei, C. J. Davis, S. Dell’Oro, M. M. Deninno, S. Di Domizio, M. L. Di Vacri, A. Drobizhev, D. Q. Fang, M. Faverzani, J. Feintzeig, G. Fernandes, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, L. Gladstone, P. Gorla, C. Gotti, T. D. Gutierrez, E. E. Haller, K. Han, E. Hansen, K. M. Heeger, R. Hennings-Yeomans, K. P. Hickerson, H. Z. Huang, R. Kadel, G. Keppel, Yu. G. Kolomensky, A. Leder, C. Ligi, K. E. Lim, X. Liu, Y. G. Ma, M. Maino, L. Marini, M. Martinez, R. H. Maruyama, Y. Mei, N. Moggi, S. Morganti, P. J. Mosteiro, T. Napolitano, C. Nones, E. B. Norman, A. Nucciotti, T. O’Donnell, F. Orio, J. L. Ouellet, C. E. Pagliarone, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, G. Piperno, C. Pira, S. Pirro, S. Pozzi, E. Previtali, C. Rosenfeld, C. Rusconi, S. Sangiorgio, D. Santone, N. D. Scielzo, V. Singh, M. Sisti, A. R. Smith, L. Taffarello, M. Tenconi, F. Terranova, C. Tomei, S. Trentalange, M. Vignati, S. L. Wagaarachchi, B. S. Wang, H. W. Wang, J. Wilson, L. A. Winslow, T. Wise, A. Woodcraft, L. Zanotti, G. Q. Zhang, B. X. Zhu, S. Zimmermann, and S. Zucchelli

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We report on a search for double beta decay of $$^{130}\hbox {Te}$$ 130Te to the first $$0^{+}$$ 0+ excited state of $$^{130}\hbox {Xe}$$ 130Xe using a $$9.8\,\hbox {kg}\cdot \hbox {yr}$$ 9.8kg·yr exposure of $$^{130}\hbox {Te}$$ 130Te collected with the CUORE-0 experiment. In this work we exploit different topologies of coincident events to search for both the neutrinoless and two-neutrino double beta decay modes. We find no evidence for either mode and place lower bounds on the half-lives: $$T^{0\nu }_{0^+_1}>7.9\cdot 10^{23}\hbox {yr}$$ T01+0ν>7.9·1023yr and $$T^{2\nu }_{0^+_1}>2.4\cdot 10^{23}\hbox {yr}$$ T01+2ν>2.4·1023yr ($$90\%\,\hbox {CL}$$ 90%CL ). Combining our results with those obtained by the CUORICINO experiment, we achieve the most stringent constraints available for these processes: $$T^{0\nu }_{0^+_1}>1.4\cdot 10^{24}\hbox {yr}$$ T01+0ν>1.4·1024yr and $$T^{2\nu }_{0^+_1}>2.5\cdot 10^{23}\hbox {yr}$$ T01+2ν>2.5·1023yr ($$90\%\,\hbox {CL}$$ 90%CL ).

Published
2019
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3. Initial performance of the COSINE-100 experiment

Author

G. Adhikari, P. Adhikari, E. Barbosa de Souza, N. Carlin, S. Choi, W. Q. Choi, M. Djamal, A. C. Ezeribe, C. Ha, I. S. Hahn, A. J. F. Hubbard, E. J. Jeon, J. H. Jo, H. W. Joo, W. G. Kang, W. Kang, M. Kauer, B. H. Kim, H. Kim, H. J. Kim, K. W. Kim, M. C. Kim, N. Y. Kim, S. K. Kim, Y. D. Kim, Y. H. Kim, V. A. Kudryavtsev, H. S. Lee, J. Lee, J. Y. Lee, M. H. Lee, D. S. Leonard, K. E. Lim, W. A. Lynch, R. H. Maruyama, F. Mouton, S. L. Olsen, H. K. Park, H. S. Park, J. S. Park, K. S. Park, W. Pettus, Z. P. Pierpoint, H. Prihtiadi, S. Ra, F. R. Rogers, C. Rott, A. Scarff, N. J. C. Spooner, W. G. Thompson, L. Yang, and S. H. Yong

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract COSINE is a dark matter search experiment based on an array of low background NaI(Tl) crystals located at the Yangyang underground laboratory. The assembly of COSINE-100 was completed in the summer of 2016 and the detector is currently collecting physics quality data aimed at reproducing the DAMA/LIBRA experiment that reported an annual modulation signal. Stable operation has been achieved and will continue for at least 2 years. Here, we describe the design of COSINE-100, including the shielding arrangement, the configuration of the NaI(Tl) crystal detection elements, the veto systems, and the associated operational systems, and we show the current performance of the experiment.

Published
2018
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4. Low energy analysis techniques for CUORE

Author

C. Alduino, K. Alfonso, D. R. Artusa, F. T. Avignone, O. Azzolini, G. Bari, J. W. Beeman, F. Bellini, G. Benato, A. Bersani, M. Biassoni, A. Branca, C. Brofferio, C. Bucci, A. Camacho, A. Caminata, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Cardani, P. Carniti, N. Casali, L. Cassina, D. Chiesa, N. Chott, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, J. S. Cushman, A. D’Addabbo, D. D’Aguanno, I. Dafinei, C. J. Davis, S. Dell’Oro, M. M. Deninno, S. Di Domizio, M. L. Di Vacri, A. Drobizhev, D. Q. Fang, M. Faverzani, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, L. Gladstone, P. Gorla, C. Gotti, T. D. Gutierrez, E. E. Haller, K. Han, E. Hansen, K. M. Heeger, R. Hennings-Yeomans, H. Z. Huang, R. Kadel, G. Keppel, Yu. G. Kolomensky, A. Leder, C. Ligi, K. E. Lim, Y. G. Ma, M. Maino, L. Marini, M. Martinez, R. H. Maruyama, Y. Mei, N. Moggi, S. Morganti, P. J. Mosteiro, T. Napolitano, M. Nastasi, C. Nones, E. B. Norman, V. Novati, A. Nucciotti, T. O’Donnell, J. L. Ouellet, C. E. Pagliarone, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, G. Pessina, G. Piperno, C. Pira, S. Pirro, S. Pozzi, E. Previtali, C. Rosenfeld, C. Rusconi, M. Sakai, S. Sangiorgio, D. Santone, B. Schmidt, J. Schmidt, N. D. Scielzo, V. Singh, M. Sisti, A. R. Smith, L. Taffarello, F. Terranova, C. Tomei, M. Vignati, S. L. Wagaarachchi, B. S. Wang, H. W. Wang, B. Welliver, J. Wilson, L. A. Winslow, T. Wise, A. Woodcraft, L. Zanotti, G. Q. Zhang, S. Zimmermann, and S. Zucchelli

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract CUORE is a tonne-scale cryogenic detector operating at the Laboratori Nazionali del Gran Sasso (LNGS) that uses tellurium dioxide bolometers to search for neutrinoless double-beta decay of $$^{130}$$ 130 Te. CUORE is also suitable to search for low energy rare events such as solar axions or WIMP scattering, thanks to its ultra-low background and large target mass. However, to conduct such sensitive searches requires improving the energy threshold to 10 keV. In this paper, we describe the analysis techniques developed for the low energy analysis of CUORE-like detectors, using the data acquired from November 2013 to March 2015 by CUORE-0, a single-tower prototype designed to validate the assembly procedure and new cleaning techniques of CUORE. We explain the energy threshold optimization, continuous monitoring of the trigger efficiency, data and event selection, and energy calibration at low energies in detail. We also present the low energy background spectrum of CUORE-0 below $$60 \, \mathrm {keV}$$ 60 keV . Finally, we report the sensitivity of CUORE to WIMP annual modulation using the CUORE-0 energy threshold and background, as well as an estimate of the uncertainty on the nuclear quenching factor from nuclear recoils inCUORE-0.

Published
2017
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5. CUORE sensitivity to $$0\nu \beta \beta $$ 0 ν β β decay

Author

C. Alduino, K. Alfonso, D. R. Artusa, F. T. Avignone, O. Azzolini, T. I. Banks, G. Bari, J. W. Beeman, F. Bellini, G. Benato, A. Bersani, M. Biassoni, A. Branca, C. Brofferio, C. Bucci, A. Camacho, A. Caminata, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Carbone, L. Cardani, P. Carniti, N. Casali, L. Cassina, D. Chiesa, N. Chott, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, J. S. Cushman, A. D’Addabbo, I. Dafinei, C. J. Davis, S. Dell’Oro, M. M. Deninno, S. Di Domizio, M. L. Di Vacri, A. Drobizhev, D. Q. Fang, M. Faverzani, G. Fernandes, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, L. Gladstone, P. Gorla, C. Gotti, T. D. Gutierrez, E. E. Haller, K. Han, E. Hansen, K. M. Heeger, R. Hennings-Yeomans, K. P. Hickerson, H. Z. Huang, R. Kadel, G. Keppel, Yu. G. Kolomensky, A. Leder, C. Ligi, K. E. Lim, Y. G. Ma, M. Maino, L. Marini, M. Martinez, R. H. Maruyama, Y. Mei, N. Moggi, S. Morganti, P. J. Mosteiro, T. Napolitano, M. Nastasi, C. Nones, E. B. Norman, V. Novati, A. Nucciotti, T. O’Donnell, J. L. Ouellet, C. E. Pagliarone, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, G. Piperno, C. Pira, S. Pirro, S. Pozzi, E. Previtali, C. Rosenfeld, C. Rusconi, M. Sakai, S. Sangiorgio, D. Santone, B. Schmidt, J. Schmidt, N. D. Scielzo, V. Singh, M. Sisti, A. R. Smith, L. Taffarello, M. Tenconi, F. Terranova, C. Tomei, S. Trentalange, M. Vignati, S. L. Wagaarachchi, B. S. Wang, H. W. Wang, B. Welliver, J. Wilson, L. A. Winslow, T. Wise, A. Woodcraft, L. Zanotti, G. Q. Zhang, B. X. Zhu, S. Zimmermann, and S. Zucchelli

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We report a study of the CUORE sensitivity to neutrinoless double beta ( $$0\nu \beta \beta $$ 0 ν β β ) decay. We used a Bayesian analysis based on a toy Monte Carlo (MC) approach to extract the exclusion sensitivity to the $$0\nu \beta \beta $$ 0 ν β β decay half-life ( $$T_{1/2}^{\,0\nu }$$ T 1 / 2 0 ν ) at $$90\%$$ 90 % credibility interval (CI) – i.e. the interval containing the true value of $$T_{1/2}^{\,0\nu }$$ T 1 / 2 0 ν with $$90\%$$ 90 % probability – and the $$3~\sigma $$ 3 σ discovery sensitivity. We consider various background levels and energy resolutions, and describe the influence of the data division in subsets with different background levels. If the background level and the energy resolution meet the expectation, CUORE will reach a $$90\%$$ 90 % CI exclusion sensitivity of $$2\cdot 10^{25}$$ 2 · 10 25 year with 3 months, and $$9\cdot 10^{25}$$ 9 · 10 25 year with 5 years of live time. Under the same conditions, the discovery sensitivity after 3 months and 5 years will be $$7\cdot 10^{24}$$ 7 · 10 24 year and $$4\cdot 10^{25}$$ 4 · 10 25 year, respectively.

Published
2017
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6. The projected background for the CUORE experiment

Author

C. Alduino, K. Alfonso, D. R. Artusa, F. T. Avignone, O. Azzolini, T. I. Banks, G. Bari, J. W. Beeman, F. Bellini, G. Benato, A. Bersani, M. Biassoni, A. Branca, C. Brofferio, C. Bucci, A. Camacho, A. Caminata, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Carbone, L. Cardani, P. Carniti, N. Casali, L. Cassina, D. Chiesa, N. Chott, M. Clemenza, S. Copello, C. Cosmelli, O. Cremonesi, R. J. Creswick, J. S. Cushman, A. D’Addabbo, I. Dafinei, C. J. Davis, S. Dell’Oro, M. M. Deninno, S. Di Domizio, M. L. Di Vacri, A. Drobizhev, D. Q. Fang, M. Faverzani, G. Fernandes, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, L. Gladstone, P. Gorla, C. Gotti, T. D. Gutierrez, E. E. Haller, K. Han, E. Hansen, K. M. Heeger, R. Hennings-Yeomans, K. P. Hickerson, H. Z. Huang, R. Kadel, G. Keppel, Yu. G. Kolomensky, A. Leder, C. Ligi, K. E. Lim, Y. G. Ma, M. Maino, L. Marini, M. Martinez, R. H. Maruyama, Y. Mei, N. Moggi, S. Morganti, P. J. Mosteiro, T. Napolitano, M. Nastasi, C. Nones, E. B. Norman, V. Novati, A. Nucciotti, T. O’Donnell, J. L. Ouellet, C. E. Pagliarone, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, G. Piperno, C. Pira, S. Pirro, S. Pozzi, E. Previtali, C. Rosenfeld, C. Rusconi, M. Sakai, S. Sangiorgio, D. Santone, B. Schmidt, J. Schmidt, N. D. Scielzo, V. Singh, M. Sisti, A. R. Smith, L. Taffarello, M. Tenconi, F. Terranova, C. Tomei, S. Trentalange, M. Vignati, S. L. Wagaarachchi, B. S. Wang, H. W. Wang, B. Welliver, J. Wilson, L. A. Winslow, T. Wise, A. Woodcraft, L. Zanotti, G. Q. Zhang, B. X. Zhu, S. Zimmermann, S. Zucchelli, and M. Laubenstein

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The Cryogenic Underground Observatory for Rare Events (CUORE) is designed to search for neutrinoless double beta decay of $$^{130}$$ 130 Te with an array of 988 TeO $$_2$$ 2 bolometers operating at temperatures around 10 mK. The experiment is currently being commissioned in Hall A of Laboratori Nazionali del Gran Sasso, Italy. The goal of CUORE is to reach a 90% C.L. exclusion sensitivity on the $$^{130}$$ 130 Te decay half-life of 9 $$\times $$ × 10 $$^{25}$$ 25 years after 5 years of data taking. The main issue to be addressed to accomplish this aim is the rate of background events in the region of interest, which must not be higher than 10 $$^{-2}$$ - 2 counts/keV/kg/year. We developed a detailed Monte Carlo simulation, based on results from a campaign of material screening, radioassays, and bolometric measurements, to evaluate the expected background. This was used over the years to guide the construction strategies of the experiment and we use it here to project a background model for CUORE. In this paper we report the results of our study and our expectations for the background rate in the energy region where the peak signature of neutrinoless double beta decay of $$^{130}$$ 130 Te is expected.

Published
2017
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7. Investing in scholarship for health professions education: Learning from the past to move into the future

Author

V. K. E. Lim, A. A. Baba, and Vishna Devi Nadarajah

Subjects
Education, Medical, 020205 medical informatics, business.industry, Malaysia, 02 engineering and technology, General Medicine, Public relations, Health professions, Investment (macroeconomics), Education, 03 medical and health sciences, Scholarship, 0302 clinical medicine, Health Occupations, Political science, 0202 electrical engineering, electronic engineering, information engineering, Key (cryptography), Humans, 030212 general & internal medicine, Fellowships and Scholarships, business, Delivery of Health Care
Abstract

There have been recent discourses of what scholarship means for health professions education (HPE) and how it may need a rethink during the pandemic. One key take home message from these discourses is the role of institutions in nurturing and investing in scholarship. Given the current challenges faced by both higher education and healthcare, there is a risk that activities and resources for scholarship in HPE may be neglected. How do institutions make a case for continuous investment in HPE scholarship? Despite being a relatively new and small private university with no public funding, IMU has made fairly significant progress in delivering a unique model of HPE programmes with HPE scholarly output. This commentary discusses the importance of investing in scholarship for HPE with the International Medical University (IMU) in Kuala Lumpur, Malaysia as a case study. Examples of institutional initiatives that support and enhance scholarship are presented based on the recent AMEE guide (142) on redefining scholarship.

Published
2021
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8. COVID-19 in adult patients with pre-existing chronic cardiac, respiratory and metabolic disease: a critical literature review with clinical recommendations

Author

Tan Kok Leong, Paul Hession, Lokman Hakim Sulaiman, V. K. E. Lim, Chee H Liew, Bryan Chang Wei Lim, and Gerard T Flaherty

Subjects
medicine.medical_specialty, lcsh:Arctic medicine. Tropical medicine, Coronavirus disease 2019 (COVID-19), lcsh:RC955-962, Disease, Review, Chronic illness, law.invention, law, Diabetes mellitus, Pandemic, Medicine, Co-morbidities, Social isolation, Metabolic disease, Intensive care medicine, Travel, Novel coronavirus, business.industry, SARS-CoV-2, Public Health, Environmental and Occupational Health, COVID-19, medicine.disease, Mental health, Intensive care unit, Infectious Diseases, medicine.symptom, business
Abstract

Background A high burden of severe disease and death from the coronavirus disease 2019 (COVID-19) has been consistently observed in older patients, especially those with pre-existing medical co-morbidities. The global pandemic lockdown has isolated many patients with chronic illnesses from their routine medical care. This narrative review article analyses the multitude of issues faced by individuals with underlying medical conditions during the COVID-19 pandemic. Methods Sources for this publication were identified through searches of PubMed for articles published between 31st December 2019 and 4th June 2020, using combinations of search terms. Guidelines and updates from reputable agencies were also consulted. Only articles published in the English language were included. Results The volume of literature on COVID-19 continues to expand, with 17,845 articles indexed on PubMed by 4th June 2020, 130 of which were deemed particularly relevant to the subject matter of this review. Older patients are more likely to progress to severe COVID-19 disease requiring intensive care unit (ICU) admission. Patients with pre-existing cardiovascular disease, especially hypertension and coronary heart disease, are at greatly increased risk of developing severe and fatal COVID-19 disease. A controversial aspect of the management of COVID-19 disease has been the use of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. Obese COVID-19 patients are more likely to require complex ICU management. Putative mechanisms of increased COVID-19 disease severity in diabetes include hyperglycaemia, altered immune function, sub-optimal glycaemic control during hospitalisation, a pro-thrombotic and pro-inflammatory state. Patients with mental health disorders are particularly vulnerable to social isolation, and this has been compounded by the suspension of non-emergency care in hospitals around the world, making it difficult for patients with chronic mental illness to attend outpatient appointments. Conclusions The global pandemic of COVID-19 disease has had a disproportionately negative impact on patients living with chronic medical illness. Future research should be directed at efforts to protect vulnerable patients from possible further waves of COVID-19 and minimising the negative impact of pandemic mitigation strategies on these individuals.

Published
2020
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9. CUORE opens the door to tonne-scale cryogenics experiments

Author

L. Canonica, L. Marini, Kevin Hickerson, J. Schmidt, Massimiliano Clemenza, Carlo Cosmelli, S. Copello, L. Gladstone, M. Guerzoni, L. Ma, J. Johnston, A. Leder, M. Iannone, Irene Nutini, Paolo Carniti, Vladimir Datskov, R. J. Creswick, M. M. Deninno, G. Fantini, F. Bellini, I. C. Bandac, Yu-Gang Ma, D. Santone, V. Sharma, C. Brofferio, P. J. Mosteiro, A. Caminata, Ezio Previtali, B. Welliver, Evelyn Ferri, H. Z. Huang, G. Keppel, K. E. Lim, X. G. Cao, F. Bragazzi, Ettore Fiorini, V. Novati, C. Rusconi, N. Chott, T. Wise, C. Crescentini, R. Gaigher, L. Zanotti, Andrea Giachero, C. Maiano, N. Moggi, C. Martinez Amaya, S. S. Nagorny, A. Pelosi, G. Piperno, D. Q. Adams, L. Risegari, K. Alfonso, F. Terranova, Davide Chiesa, C. Rosenfeld, Deqing Fang, S. Pagan, S. Dell'Oro, M. L. Di Vacri, D. Mayer, Samuele Sangiorgio, Stefano Nisi, P. T. Surukuchi, S. Morganti, S. Zucchelli, J. Camilleri, A. Nucciotti, M. Sisti, P. Gorla, E. V. Hansen, F. Ferroni, C. Tomei, Elena Sala, L. Ioannucci, D. Speller, F. Alessandria, M. I. Martínez, Eugene E. Haller, C. Alduino, F. Rimondi, G. Ceruti, K. Wilson, L. Taffarello, Marisa Pedretti, R. Hennings-Yeomans, S. Pirro, Carlo Ligi, M. Faverzani, M. Beretta, Y. Mei, M. Tessaro, Jeffrey W. Beeman, M. Capodiferro, A. Bersani, N. D. Scielzo, M. Barucci, L. Cappelli, D. Biare, C. J. Davis, A. Camacho, Jonathan Ouellet, D. Conventi, J. Wallig, K. M. Heeger, L. Pagnanini, A. Giuliani, G. Bari, M. Cariello, Lindley Winslow, A. Campani, S. L. Wagaarachchi, M. Maino, Guoqiang Zhang, M. Carrettoni, R. Mazza, A. Branca, A. Bryant, J. Nikkel, C. Pira, H.W. Wang, M. Perego, T. I. Banks, S. Zimmermann, Ke Han, Reina H. Maruyama, S. Ghislandi, T. O'Donnell, S. Di Domizio, Simone Capelli, R. W. Kadel, Stuart J. Freedman, G. Ventura, A. Drobizhev, C. Bulfon, C. Zarra, Laura Cardani, V. Dompè, M. Balata, L. Di Paolo, A. D'Addabbo, L. Pattavina, B. K. Fujikawa, Stefano Pozzi, Alan R. Smith, D. Orlandi, Larissa M. Ejzak, M. Vignati, B. X. Zhu, V. Pettinacci, L. Kogler, E. Celi, L. Tatananni, S.H. Fu, E. Andreotti, M. A. Franceschi, R. Cereseto, I. Dafinei, M. Sakai, D. D'Aguanno, F. Stivanello, R. G. Huang, D. Schaeffer, C. Guandalini, F. Orio, Vasundhara Singh, B. Schmidt, B. S. Wang, O. Azzolini, Kai Vetter, M. Olcese, Jeremy S. Cushman, V. Palmieri, Eric B. Norman, M. Guetti, T. Napolitano, M. Biassoni, F. Del Corso, R. Faccini, Giovanni Benato, A. Buccheri, C. Salvioni, Yu. G. Kolomensky, R. Pedrotta, Lorenzo Cassina, C. Nones, A. Puiu, Marco Pallavicini, S. Quitadamo, G. Pessina, James R. Wilson, R. Liu, Massimiliano Nastasi, M. Pavan, E. Olivieri, L. Gironi, F. T. Avignone, Claudio Gotti, N. Casali, F. Reindl, Oliviero Cremonesi, J. Goett, M. Tenconi, C. Pagliarone, C. Rossi, A. Chiarini, C. Bucci, T. D. Gutierrez, Adams, D, Alduino, C, Alessandria, F, Alfonso, K, Andreotti, E, Avignone, F, Azzolini, O, Balata, M, Bandac, I, Banks, T, Bari, G, Barucci, M, Beeman, J, Bellini, F, Benato, G, Beretta, M, Bersani, A, Biare, D, Biassoni, M, Bragazzi, F, Branca, A, Brofferio, C, Bryant, A, Buccheri, A, Bucci, C, Bulfon, C, Camacho, A, Camilleri, J, Caminata, A, Campani, A, Canonica, L, Cao, X, Capelli, S, Capodiferro, M, Cappelli, L, Cardani, L, Cariello, M, Carniti, P, Carrettoni, M, Casali, N, Cassina, L, Celi, E, Cereseto, R, Ceruti, G, Chiarini, A, Chiesa, D, Chott, N, Clemenza, M, Conventi, D, Copello, S, Cosmelli, C, Cremonesi, O, Crescentini, C, Creswick, R, Cushman, J, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Datskov, V, Davis, C, Corso, F, Dell'Oro, S, Deninno, M, Di Domizio, S, Dompe, V, Di Vacri, M, Di Paolo, L, Drobizhev, A, Ejzak, L, Faccini, R, Fang, D, Fantini, G, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fu, S, Fujikawa, B, Gaigher, R, Ghislandi, S, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Goett, J, Gorla, P, Gotti, C, Guandalini, C, Guerzoni, M, Guetti, M, Gutierrez, T, Haller, E, Han, K, Hansen, E, Heeger, K, Hennings-Yeomans, R, Hickerson, K, Huang, R, Huang, H, Iannone, M, Ioannucci, L, Johnston, J, Kadel, R, Keppel, G, Kogler, L, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Liu, R, Ma, L, Ma, Y, Maiano, C, Maino, M, Marini, L, Martinez, M, Amaya, C, Maruyama, R, Mayer, D, Mazza, R, Mei, Y, Moggi, N, Morganti, S, Mosteiro, P, Nagorny, S, Napolitano, T, Nastasi, M, Nikkel, J, Nisi, S, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Olcese, M, Olivieri, E, Orio, F, Orlandi, D, Ouellet, J, Pagan, S, Pagliarone, C, Pagnanini, L, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pedretti, M, Pedrotta, R, Pelosi, A, Perego, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Puiu, A, Quitadamo, S, Reindl, F, Rimondi, F, Risegari, L, Rosenfeld, C, Rossi, C, Rusconi, C, Sakai, M, Sala, E, Salvioni, C, Sangiorgio, S, Santone, D, Schaeffer, D, Schmidt, B, Schmidt, J, Scielzo, N, Sharma, V, Singh, V, Sisti, M, Smith, A, Speller, D, Stivanello, F, Surukuchi, P, Taffarello, L, Tatananni, L, Tenconi, M, Terranova, F, Tessaro, M, Tomei, C, Ventura, G, Vetter, K, Vignati, M, Wagaarachchi, S, Wallig, J, Wang, B, Wang, H, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zarra, C, Zhang, G, Zhu, B, Zimmermann, S, Zucchelli, S, Adams D.Q., Alduino C., Alessandria F., Alfonso K., Andreotti E., Avignone F.T., Azzolini O., Balata M., Bandac I., Banks T.I., Bari G., Barucci M., Beeman J.W., Bellini F., Benato G., Beretta M., Bersani A., Biare D., Biassoni M., Bragazzi F., Branca A., Brofferio C., Bryant A., Buccheri A., Bucci C., Bulfon C., Camacho A., Camilleri J., Caminata A., Campani A., Canonica L., Cao X.G., Capelli S., Capodiferro M., Cappelli L., Cardani L., Cariello M., Carniti P., Carrettoni M., Casali N., Cassina L., Celi E., Cereseto R., Ceruti G., Chiarini A., Chiesa D., Chott N., Clemenza M., Conventi D., Copello S., Cosmelli C., Cremonesi O., Crescentini C., Creswick R.J., Cushman J.S., D'Addabbo A., D'Aguanno D., Dafinei I., Datskov V., Davis C.J., Del Corso F., Dell'Oro S., Deninno M.M., Di Domizio S., Dompe V., Di Vacri M.L., Di Paolo L., Drobizhev A., Ejzak L., Faccini R., Fang D.Q., Fantini G., Faverzani M., Ferri E., Ferroni F., Fiorini E., Franceschi M.A., Freedman S.J., Fu S.H., Fujikawa B.K., Gaigher R., Ghislandi S., Giachero A., Gironi L., Giuliani A., Gladstone L., Goett J., Gorla P., Gotti C., Guandalini C., Guerzoni M., Guetti M., Gutierrez T.D., Haller E.E., Han K., Hansen E.V., Heeger K.M., Hennings-Yeomans R., Hickerson K.P., Huang R.G., Huang H.Z., Iannone M., Ioannucci L., Johnston J., Kadel R., Keppel G., Kogler L., Kolomensky Y.G., Leder A., Ligi C., Lim K.E., Liu R., Ma L., Ma Y.G., Maiano C., Maino M., Marini L., Martinez M., Amaya C.M., Maruyama R.H., Mayer D., Mazza R., Mei Y., Moggi N., Morganti S., Mosteiro P.J., Nagorny S.S., Napolitano T., Nastasi M., Nikkel J., Nisi S., Nones C., Norman E.B., Novati V., Nucciotti A., Nutini I., O'Donnell T., Olcese M., Olivieri E., Orio F., Orlandi D., Ouellet J.L., Pagan S., Pagliarone C.E., Pagnanini L., Pallavicini M., Palmieri V., Pattavina L., Pavan M., Pedretti M., Pedrotta R., Pelosi A., Perego M., Pessina G., Pettinacci V., Piperno G., Pira C., Pirro S., Pozzi S., Previtali E., Puiu A., Quitadamo S., Reindl F., Rimondi F., Risegari L., Rosenfeld C., Rossi C., Rusconi C., Sakai M., Sala E., Salvioni C., Sangiorgio S., Santone D., Schaeffer D., Schmidt B., Schmidt J., Scielzo N.D., Sharma V., Singh V., Sisti M., Smith A.R., Speller D., Stivanello F., Surukuchi P.T., Taffarello L., Tatananni L., Tenconi M., Terranova F., Tessaro M., Tomei C., Ventura G., Vetter K.J., Vignati M., Wagaarachchi S.L., Wallig J., Wang B.S., Wang H.W., Welliver B., Wilson J., Wilson K., Winslow L.A., Wise T., Zanotti L., Zarra C., Zhang G.Q., Zhu B.X., Zimmermann S., Zucchelli S., Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, and CUORE

Subjects
Cryostat, Nuclear and High Energy Physics, Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, FOS: Physical sciences, Cryogenic temperatures, Dilution refrigerator, Low temperature calorimeter, Neutrinoless double beta decay, Rare event searches, Ton-scale detector, Cryogenic temperatures, Neutrinoless double beta decay, Dilution refrigerator, Ton-scale detector, Low temperature calorimeter, Rare event searches, cryogenics, CUORE performance, Cryogenics, Rare event searche, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 7. Clean energy, 01 natural sciences, CUORE, double-beta decay: (0neutrino), Double beta decay, 0103 physical sciences, Cryogenic particle detectors, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Nuclear Experiment (nucl-ex), Aerospace engineering, 010306 general physics, Nuclear Experiment, activity report, Physics, 010308 nuclear & particles physics, business.industry, Astrophysics::Instrumentation and Methods for Astrophysics, Cryogenic temperature, Instrumentation and Detectors (physics.ins-det), CUORE performance, Semiconductor detector, cryogenics: design, cryogenics, Neutrino, business, performance
Abstract

The past few decades have seen major developments in the design and operation of cryogenic particle detectors. This technology offers an extremely good energy resolution - comparable to semiconductor detectors - and a wide choice of target materials, making low temperature calorimetric detectors ideal for a variety of particle physics applications. Rare event searches have continued to require ever greater exposures, which has driven them to ever larger cryogenic detectors, with the CUORE experiment being the first to reach a tonne-scale, mK-cooled, experimental mass. CUORE, designed to search for neutrinoless double beta decay, has been operational since 2017 at a temperature of about 10 mK. This result has been attained by the use of an unprecedentedly large cryogenic infrastructure called the CUORE cryostat: conceived, designed and commissioned for this purpose. In this article the main characteristics and features of the cryogenic facility developed for the CUORE experiment are highlighted. A brief introduction of the evolution of the field and of the past cryogenic facilities are given. The motivation behind the design and development of the CUORE cryogenic facility is detailed as are the steps taken toward realization, commissioning, and operation of the CUORE cryostat. The major challenges overcome by the collaboration and the solutions implemented throughout the building of the cryogenic facility will be discussed along with the potential improvements for future facilities. The success of CUORE has opened the door to a new generation of large-scale cryogenic facilities in numerous fields of science. Broader implications of the incredible feat achieved by the CUORE collaboration on the future cryogenic facilities in various fields ranging from neutrino and dark matter experiments to quantum computing will be examined., Comment: 45 pages, 14 figures

Published
2022
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10. Prediction models used in the progression of chronic kidney disease: A scoping review

Author

David K. E. Lim, James H. Boyd, Elizabeth Thomas, Aron Chakera, Sawitchaya Tippaya, Ashley Irish, Justin Manuel, Kim Betts, and Suzanne Robinson

Subjects
Multidisciplinary, Disease Progression, Humans, Kidney Failure, Chronic, Renal Insufficiency, Chronic, Delivery of Health Care, Uncategorized
Abstract

Objective To provide a review of prediction models that have been used to measure clinical or pathological progression of chronic kidney disease (CKD). Design Scoping review. Data sources Medline, EMBASE, CINAHL and Scopus from the year 2011 to 17th February 2022. Study selection All English written studies that are published in peer-reviewed journals in any country, that developed at least a statistical or computational model that predicted the risk of CKD progression. Data extraction Eligible studies for full text review were assessed on the methods that were used to predict the progression of CKD. The type of information extracted included: the author(s), title of article, year of publication, study dates, study location, number of participants, study design, predicted outcomes, type of prediction model, prediction variables used, validation assessment, limitations and implications. Results From 516 studies, 33 were included for full-text review. A qualitative analysis of the articles was compared following the extracted information. The study populations across the studies were heterogenous and data acquired by the studies were sourced from different levels and locations of healthcare systems. 31 studies implemented supervised models, and 2 studies included unsupervised models. Regardless of the model used, the predicted outcome included measurement of risk of progression towards end-stage kidney disease (ESKD) of related definitions, over given time intervals. However, there is a lack of reporting consistency on details of the development of their prediction models. Conclusions Researchers are working towards producing an effective model to provide key insights into the progression of CKD. This review found that cox regression modelling was predominantly used among the small number of studies in the review. This made it difficult to perform a comparison between ML algorithms, more so when different validation methods were used in different cohort types. There needs to be increased investment in a more consistent and reproducible approach for future studies looking to develop risk prediction models for CKD progression.

Published
2022
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11. Transfer of knowledge, skills and confidence from a faculty development programme for health professions educators into practice

Author

C. F. Chia, Vishna Devi Nadarajah, S. Kutzsche, and V. K. E. Lim

Subjects
Medical education, Teaching, education, Professional development, General Medicine, Health professions, Faculty, Education, Health Occupations, Humans, Learning, Faculty development, Psychology, Teaching learning
Abstract

Faculty development programmes should incorporate the transfer of knowledge, skills, and confidence from the training to educational practice. However, there is a risk that transfer may fail due to inadequate integration of knowledge, skills, and confidence. The study evaluated transfer levels, guided by learned principles from a faculty development programme.The submitted self-reports on a pedagogical intervention of 92 out of 190 health professions educators who participated in a mandatory teaching and learning training programme, were analysed by a mixed-method approach guided by a structured conceptual framework.Overall 93.4% reported the successful transfer of learning. Participants incorporated sustainable changed practice (level A, 57.6%), showed reflection on the impact of changed practice (level B, 21.7%), and performed effect analysis (level C, 14.1%). The rest planned application of learning (level D, 4.4%) and identified gaps in current practice or developed an idea for educational intervention but did not implement (level E, 2.2%).The majority of participants transferred their learning. Faculty development programmes must ensure successful transfer of knowledge, skills, and confidence from the training to educational practice to ensure sustainable development of teaching and learning practices.

Published
2020

12. Double-beta decay of $^{130}\hbox {Te}$ to the first $0^+$ excited state of $^{130}\hbox {Xe}$ with CUORE-0

Author

Alan R. Smith, Massimiliano Clemenza, Carlo Cosmelli, Oliviero Cremonesi, L. Canonica, L. Marini, Kevin Hickerson, L. Gladstone, M. Faverzani, C. Rosenfeld, R. Hennings-Yeomans, P. Gorla, F. Ferroni, B. X. Zhu, C. Tomei, S. Zucchelli, R. J. Creswick, Emanuele Ferri, Eugene E. Haller, C. Brofferio, James R. Wilson, P. J. Mosteiro, S. Zimmermann, C. Bucci, T. D. Gutierrez, Miriam Lucio Martinez, S. Morganti, D. R. Artusa, Monica Sisti, V. Palmieri, C. J. Davis, L. Carbone, N. Casali, A. Camacho, S. Copello, Eric B. Norman, T. Napolitano, Jeremy S. Cushman, G. Piperno, G. Bari, L. Zanotti, Ke Han, Reina H. Maruyama, Yu. G. Kolomensky, Luigi Cappelli, Davide Chiesa, K. E. Lim, Paolo Carniti, N. D. Scielzo, S. L. Wagaarachchi, Stuart J. Freedman, L. Taffarello, M. Maino, Lorenzo Cassina, Jeffrey W. Beeman, S. Trentalange, M. Biassoni, M. M. Deninno, S. Di Domizio, Y. Mei, I. Dafinei, Guimin Zhang, A. Bersani, A. D'Addabbo, N. Moggi, Simone Capelli, R. W. Kadel, M. Pavan, L. Gironi, F. T. Avignone, Claudio Gotti, H. Z. Huang, B. K. Fujikawa, S. Pirro, Stefano Dell'Oro, Carlo Ligi, Stefano Pozzi, C. Pira, Samuele Sangiorgio, H. W. Wang, G. Keppel, Xi-Guang Cao, A. Leder, F. Bellini, A. Nucciotti, Yu-Gang Ma, T. O'Donnell, A. Caminata, Ezio Previtali, T. I. Banks, K. M. Heeger, M. Vignati, A. Woodcraft, X. Liu, A. Giuliani, G. Fernandes, C. Alduino, F. Orio, Vasundhara Singh, J. Feintzeig, D. Santone, F. Terranova, Ettore Fiorini, E. V. Hansen, N. Chott, M. Tenconi, B. S. Wang, Marco Pallavicini, O. Azzolini, G. Pessina, K. Alfonso, M. L. Di Vacri, C. Nones, C. Rusconi, V. Pettinacci, L. Cardani, Lindley Winslow, L. Pattavina, A. Drobizhev, M. A. Franceschi, A. Giachero, D. Q. Fang, J. L. Ouellet, C. Pagliarone, T. Wise, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, CUORE, and Département de Physique des Particules (ex SPP) (DPhP)

Subjects
Semileptonic decay, topology, Physics and Astronomy (miscellaneous), energy levels: splitting, data acquisition, detector: mass, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 01 natural sciences, energy: transition, CUORE, background: low, double-beta decay: (0neutrino), Double beta decay, 0103 physical sciences, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, Engineering (miscellaneous), Physics, S076H0N, 010308 nuclear & particles physics, excited state: energy, particle: Majorana, semileptonic decay, Excited state, xenon: nuclide, tellurium: nuclide, Neutrino, Atomic physics, Radioactive decay
Abstract

We report on a search for double beta decay of $$^{130}\hbox {Te}$$130Te to the first $$0^{+}$$0+ excited state of $$^{130}\hbox {Xe}$$130Xe using a $$9.8\,\hbox {kg}\cdot \hbox {yr}$$9.8kg·yr exposure of $$^{130}\hbox {Te}$$130Te collected with the CUORE-0 experiment. In this work we exploit different topologies of coincident events to search for both the neutrinoless and two-neutrino double beta decay modes. We find no evidence for either mode and place lower bounds on the half-lives: $$T^{0\nu }_{0^+_1}>7.9\cdot 10^{23}\hbox {yr}$$T01+0ν>7.9·1023yr and $$T^{2\nu }_{0^+_1}>2.4\cdot 10^{23}\hbox {yr}$$T01+2ν>2.4·1023yr ($$90\%\,\hbox {CL}$$90%CL). Combining our results with those obtained by the CUORICINO experiment, we achieve the most stringent constraints available for these processes: $$T^{0\nu }_{0^+_1}>1.4\cdot 10^{24}\hbox {yr}$$T01+0ν>1.4·1024yr and $$T^{2\nu }_{0^+_1}>2.5\cdot 10^{23}\hbox {yr}$$T01+2ν>2.5·1023yr ($$90\%\,\hbox {CL}$$90%CL).

Published
2019
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13. First Results from CUORE: A Search for Lepton Number Violation via 0νββ Decay of Te130

Author

R. Gaigher, Massimiliano Clemenza, Carlo Cosmelli, Marisa Pedretti, M. M. Deninno, C. Nones, F. Rimondi, R. Cereseto, I. Dafinei, C. Brofferio, G. Pessina, K. Wilson, Davide Chiesa, A. Caminata, Ezio Previtali, Marco Pallavicini, Jonathan Ouellet, Y. G. Ma, G. Bari, B. Welliver, C. Crescentini, H. Z. Huang, Jeffrey W. Beeman, M. Capodiferro, N. D. Scielzo, G. Keppel, K. E. Lim, E. V. Hansen, A. Bersani, Lucia Canonica, Stefano Dell'Oro, J. Schmidt, L. Ioannucci, S. Di Domizio, V. Pettinacci, F. Bellini, X. Liu, N. Casali, D. D'Aguanno, L. Gladstone, F. Bragazzi, D. Schaeffer, A. Giuliani, M. Guerzoni, P. J. Mosteiro, J. Wallig, C. Maiano, C. Zarra, Laura Cardani, I. C. Bandac, S. S. Nagorny, M. Pavan, R. J. Creswick, N. Chott, B. K. Fujikawa, C. Rusconi, R. Hennings-Yeomans, S. L. Wagaarachchi, Eric B. Norman, C. Pagliarone, M. Vignati, B. X. Zhu, C. Martinez Amaya, C. Arnaboldi, Lindley Winslow, R. W. Kadel, Stefano Zucchelli, S. Zimmermann, K. Alfonso, F. Reindl, M. L. Di Vacri, M. Maino, C. Rossi, M. Faverzani, M. Iannone, C. Bucci, T. D. Gutierrez, Miriam Lucio Martinez, Irene Nutini, Vladimir Datskov, B. S. Wang, G. Ventura, L. Tatananni, A. Chiarini, F. Stivanello, S. Copello, T. I. Banks, Paolo Carniti, C. Bulfon, M. Balata, L. Pattavina, C. Salvioni, L. Zanotti, Jeremy S. Cushman, L. Gironi, G. Piperno, M. Tenconi, F. T. Avignone, F. Orio, Claudio Gotti, M. Cariello, L. Taffarello, B. Schmidt, V. Novati, Virendra Singh, Oliviero Cremonesi, J. Goett, Guimin Zhang, Y. Mei, C. Pira, M. Tessaro, E. Andreotti, O. Azzolini, L. Di Paolo, A. D'Addabbo, Larissa M. Ejzak, M. Sakai, Silvia Capelli, S. Pirro, Xi-Guang Cao, Massimiliano Nastasi, Carlo Ligi, M. Barucci, D. Biare, K. M. Heeger, M. Carrettoni, C. Rosenfeld, P. Gorla, F. Ferroni, C. Tomei, A. Bryant, Emanuele Ferri, Eugene E. Haller, G. Ceruti, C. J. Davis, A. Camacho, L. Kogler, S. Morganti, F. Terranova, S. Pozzi, E. Olivieri, James R. Wilson, E. Fiorini, A. Pelosi, Alan R. Smith, Ke Han, A. Branca, Reina H. Maruyama, N. Moggi, H. W. Wang, Stuart J. Freedman, T. O'Donnell, A. Leder, L. Risegari, Samuele Sangiorgio, Stefano Nisi, T. Wise, A. Nucciotti, M. Sisti, C. Alduino, D. Santone, Yu. G. Kolomensky, Luigi Cappelli, F. Alessandria, R. Pedrotta, D. Conventi, L. Marini, Kevin Hickerson, C. Guandalini, E. Sala, V. Palmieri, A. Giachero, T. Napolitano, D. Q. Fang, M. Biassoni, A. Buccheri, M. Olcese, F. Del Corso, R. Faccini, Giovanni Benato, L. Cassina, A. Drobizhev, D. Orlandi, and M. A. Franceschi

Subjects
Physics, Particle physics, 010308 nuclear & particles physics, Bolometer, Statistical sensitivity, General Physics and Astronomy, 01 natural sciences, Lepton number, law.invention, MAJORANA, Full width at half maximum, CUORE, law, Double beta decay, 0103 physical sciences, Neutrino, 010306 general physics
Abstract

The CUORE experiment, a ton-scale cryogenic bolometer array, recently began operation at the Laboratori Nazionali del Gran Sasso in Italy. The array represents a significant advancement in this technology, and in this work we apply it for the first time to a high-sensitivity search for a lepton-number-violating process: ^{130}Te neutrinoless double-beta decay. Examining a total TeO_{2} exposure of 86.3 kg yr, characterized by an effective energy resolution of (7.7±0.5) keV FWHM and a background in the region of interest of (0.014±0.002) counts/(keV kg yr), we find no evidence for neutrinoless double-beta decay. Including systematic uncertainties, we place a lower limit on the decay half-life of T_{1/2}^{0ν}(^{130}Te)>1.3×10^{25} yr (90% C.L.); the median statistical sensitivity of this search is 7.0×10^{24} yr. Combining this result with those of two earlier experiments, Cuoricino and CUORE-0, we find T_{1/2}^{0ν}(^{130}Te)>1.5×10^{25} yr (90% C.L.), which is the most stringent limit to date on this decay. Interpreting this result as a limit on the effective Majorana neutrino mass, we find m_{ββ}

Published
2018
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14. Study of Rare Nuclear Processes with CUORE

Author

C. Pira, L. Canonica, L. Marini, T. Wise, L. Taffarello, C. Pagliarone, Vasundhara Singh, A. Bersani, B. Schmidt, B. S. Wang, O. Azzolini, Carlo Cosmelli, L. Gladstone, H. Z. Huang, G. Keppel, K. E. Lim, C. Brofferio, Davide Chiesa, C. Rusconi, A. Drobizhev, R. J. Creswick, M. Faverzani, Oliviero Cremonesi, M. M. Deninno, M. A. Franceschi, Marco Pallavicini, L. Pattavina, L. Gironi, F. Bellini, F. T. Avignone, Jeremy S. Cushman, G. Pessina, M. Pavan, C. Rosenfeld, S. Pirro, Nicholas Scielzo, P. Gorla, F. Ferroni, C. Tomei, Emanuele Ferri, C. J. Davis, A. Camacho, James R. Wilson, Giovanni Benato, C. Bucci, T. D. Gutierrez, H. W. Wang, T. O'Donnell, Monica Sisti, V. Palmieri, S. Di Domizio, D. Q. Fang, N. Casali, S. Zucchelli, Eric B. Norman, Laura Cardani, B. K. Fujikawa, Stefano Pozzi, T. Napolitano, N. Moggi, Silvia Capelli, F. Reindl, M. Vignati, Massimiliano Nastasi, V. Novati, M. Biassoni, C. Nones, Samuele Sangiorgio, A. Nucciotti, C. Alduino, K. Wilson, Ettore Fiorini, Jonathan Ouellet, G. Bari, Andrea Giachero, K. Alfonso, M. I. Martínez, M. L. Di Vacri, Lorenzo Cassina, Yu. G. Kolomensky, D. Santone, S. Zimmermann, Ioan Dafinei, S. Copello, L. Zanotti, Paolo Carniti, Claudio Gotti, Stefano Dell'Oro, M. Clemenza, A. Giuliani, N. Chott, S. L. Wagaarachchi, D. D'Aguanno, S. Morganti, S. S. Nagorny, Lindley Winslow, L. Cappelli, A. Leder, Irene Nutini, Y. Mei, V. Dompè, Yu-Gang Ma, A. Caminata, M. Sakai, Ezio Previtali, R. Hennings-Yeomans, Xi-Guang Cao, A. D'Addabbo, B. Welliver, K. M. Heeger, Carlo Ligi, J. Schmidt, Ke Han, A. Branca, Reina H. Maruyama, Stuart J. Freedman, F. Terranova, Guimin Zhang, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, CUORE, Alduino, C., Alfonso, K., Avignone, F.T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., Camacho, A., Caminata, A., Canonica, L., Cao, X.G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R.J., Cushman, J.S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C.J., Dell'Oro, S., Deninno, M.M., Di Domizio, S., Di Vacri, M.L., Dompe, V., Drobizhev, A., Fang, D.Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M.A., Freedman, S.J., Fujikawa, B.K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T.D., Han, K., Heeger, K.M., Hennings-Yeomans, R., Huang, H.Z., Keppel, G., Kolomensky, Yu.G., Leder, A., Ligi, C., Lim, K.E., Ma, Y.G., Marini, L., Martinez, M., Maruyama, R.H., Mei, Y., Moggi, N., Morganti, S., Nagorny, S.S., Napolitano, T., Nastasi, M., Nones, C., Norman, E.B., Novati, V., Nucciotti, A., Nutini, I., O'Donnell, T., Ouellet, J.L., Pagliarone, C.E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Reindl, F., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Schmidt, J., Scielzo, N.D., Singh, V., Sisti, M., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S.L., Wang, B.S., Wang, H.W., Welliver, B., Wilson, J., Wilson, K., Winslow, L.A., Wise, T., Zanotti, L., Zhang, G.Q., Zimmermann, S., Zucchelli, S., Centre de Sciences Nucléaires et de Sciences de la Matière ( CSNSM ), Université Paris-Sud - Paris 11 ( UP11 ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Département de Physique des Particules (ex SPP) ( DPP ), Institut de Recherches sur les lois Fondamentales de l'Univers ( IRFU ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D’Addabbo, A, D’Aguanno, D, Dafinei, I, Davis, C, Dell’Oro, S, Deninno, M, Di Domizio, S, Di Vacri, M, Dompè, V, Drobizhev, A, Fang, D, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Hennings-Yeomans, R, Huang, H, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Ma, Y, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Nagorny, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O’Donnell, T, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, N, Singh, V, Sisti, M, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zhang, G, Zimmermann, S, Zucchelli, S, and Département de Physique des Particules (ex SPP) (DPhP)

Subjects
Second-order weak decay, Particle physics, CUORE, Double beta decay, Low-temperature detectors, Rare events searches, Second-order weak decays, Atomic and Molecular Physics, and Optics, Nuclear and High Energy Physics, Astronomy and Astrophysics, Physics - Instrumentation and Detectors, Atomic and Molecular Physics, and Optic, rare events searches, FOS: Physical sciences, double beta decay, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 7. Clean energy, 01 natural sciences, Low-temperature detector, low-temperature detectors, 23.40.-s, 07.57.Kp, second-order weak decays, Atomic and Molecular Physics, 0103 physical sciences, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Nuclear Experiment (nucl-ex), [ PHYS.NEXP ] Physics [physics]/Nuclear Experiment [nucl-ex], Detector array, 010306 general physics, Nuclear Experiment, [ PHYS.PHYS.PHYS-INS-DET ] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Nuclear and High Energy Physic, Physics, 010308 nuclear & particles physics, Instrumentation and Detectors (physics.ins-det), Neutrino, and Optics, Rare events searche, Tellurium compounds, FIS/04 - FISICA NUCLEARE E SUBNUCLEARE, Radioactive decay, 07.20.Mc
Abstract

TeO2 bolometers have been used for many years to search for neutrinoless double beta decay in 130-Te. CUORE, a tonne-scale TeO2 detector array, recently published the most sensitive limit on the half-life, $T_{1/2}^{0��} > 1.5 \times 10^{25}\,$yr, which corresponds to an upper bound of $140-400$~meV on the effective Majorana mass of the neutrino. While it makes CUORE a world-leading experiment looking for neutrinoless double beta decay, it is not the only study that CUORE will contribute to in the field of nuclear and particle physics. As already done over the years with many small-scale experiments, CUORE will investigate both rare decays (such as the two-neutrino double beta decay of 130-Te and the hypothesized electron capture in 123-Te), and rare processes (e.g., dark matter and axion interactions). This paper describes some of the achievements of past experiments that used TeO2 bolometers, and perspectives for CUORE., 36 pages, 13 figures, sumbitted to IJMPA Special Issue "Results and Developments in the investigation of rare nuclear decays and processes"

Published
2018
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15. Initial performance of the COSINE-100 experiment

Author

Z. P. Pierpoint, Yong Hamb Kim, S.H. Yong, F. R. Rogers, W. A. Lynch, W.G. Kang, N.Y. Kim, Hongjoo Kim, Hansoo Park, H. Prihtiadi, N. J. C. Spooner, V. A. Kudryavtsev, P. Adhikari, E. Barbosa de Souza, A. C. Ezeribe, Stephen L. Olsen, Kangsoon Park, M. Kauer, J.S. Park, A. Scarff, J. H. Jo, Seonho Choi, Insik Hahn, W. Q. Choi, W. Kang, Liang Yang, W. G. Thompson, Govinda Adhikari, Eunju Jeon, F. Mouton, Jimmy H. M. Lee, H. W. Joo, K. E. Lim, Reina H. Maruyama, Walter C. Pettus, Hyun Su Lee, A. J. F. Hubbard, M.C. Kim, K. W. Kim, Mitra Djamal, Carsten Rott, Moo Hyun Lee, C. Ha, S. J. Ra, H. Kim, Joo Young Lee, B.H. Kim, N. Carlin, Sun Kee Kim, D. S. Leonard, Y.D. Kim, Hyang Kyu Park, Massachusetts Institute of Technology. Department of Physics, and Rogers, Field Rose

Subjects
Physics - Instrumentation and Detectors, Physics and Astronomy (miscellaneous), Dark matter, FOS: Physical sciences, lcsh:Astrophysics, 7. Clean energy, 01 natural sciences, Signal, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), Optics, lcsh:QB460-466, 0103 physical sciences, Trigonometric functions, ddc:530, lcsh:Nuclear and particle physics. Atomic energy. Radioactivity, 010306 general physics, Instrumentation and Methods for Astrophysics (astro-ph.IM), Engineering (miscellaneous), Physics, 010308 nuclear & particles physics, business.industry, Detector, Instrumentation and Detectors (physics.ins-det), Modulation, Electromagnetic shielding, Underground laboratory, lcsh:QC770-798, business, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

COSINE is a dark matter search experiment based on an array of low background NaI(Tl) crystals located at the Yangyang underground laboratory. The assembly of COSINE-100 was completed in the summer of 2016 and the detector is currently collecting physics quality data aimed at reproducing the DAMA/LIBRA experiment that reported an annual modulation signal. Stable operation has been achieved and will continue for at least 2 years. Here, we describe the design of COSINE-100, including the shielding arrangement, the configuration of the NaI(Tl) crystal detection elements, the veto systems, and the associated operational systems, and we show the current performance of the experiment., Institute for Basic Science ( IBS-R016-A1), University of Illinois at Urbana-Champaign, Alfred P. Sloan Foundation (Fellowship), National Science Foundation (U.S.) (Grant PHY-1457995), National Science Foundation (U.S.) (Grant PHY-1151795), National Science Foundation (U.S.) (Grant DGE-1122492), National Science Foundation (U.S.) (Grant DGE1256259), Wisconsin IceCube Particle Astrophysics Center, University of Wisconsin. Alumni Research Foundation, Yale University, United States. National Nuclear Security Administration (Grant DE-FC52-08NA28752), Science and Technology Facilities Council (Great Britain) (Grant ST/N000277/1), Science and Technology Facilities Council (Great Britain) (Grant ST/K001337/1), Conselho Nacional de Pesquisas (Brazil) (Grant 2017/02952-0 FAPESP)

Published
2017

16. CUORE: first results and prospects

Author

A. Leder, A. Bersani, T. Wise, D. Santone, Giovanni Benato, Ioan Dafinei, M. Faverzani, Y. u. G. Kolomensky, Ettore Fiorini, J. S. Wilson, L. Taffarello, Oliviero Cremonesi, Andrea Giachero, C. Pagliarone, Laura Cardani, V. Palmieri, R. Hennings-Yeomans, Eric B. Norman, Silvio Morganti, T. D. Gutierrez, F. Terranova, T. Napolitano, B. K. Fujikawa, Stefano Pozzi, M. Biassoni, S. S. Nagorny, Vivek Singh, N. Chott, Ezio Previtali, B. Welliver, K. Alfonso, Luigi Cappelli, Davide Chiesa, Massimiliano Clemenza, Carlo Cosmelli, M. Vignati, K. E. Lim, A. Drobizhev, H. Z. Huang, L. Zanotti, Lindley Winslow, Nicholas Scielzo, Lorenzo Cassina, Laura Gladstone, Deqing Fang, C. Brofferio, Claudia Nones, J. Schmidt, Hongwei Wang, Carlo Ligi, K. Wilson, R. J. Creswick, M. A. Franceschi, T. O'Donnell, C. Rusconi, Jonathan Ouellet, G. Bari, Claudio Gotti, Marco Pallavicini, L. Pattavina, Irene Nutini, N. Casali, Yu-Gang Ma, G. Pessina, M. M. Deninno, F. Reindl, Lucia Canonica, F. Bellini, Guoqiang Zhang, V. Novati, G. Keppel, Ke Han, A. Branca, Reina H. Maruyama, Stefano Pirro, L. Marini, D. D'Aguanno, Y. Mei, M. Sakai, Xi-Guang Cao, K. M. Heeger, M. I. Martínez, A. Giuliani, N. Moggi, V. Dompè, Jeremy S. Cushman, C. Pira, Samuele Sangiorgio, Stefano Dell'Oro, A. Nucciotti, Claudia Tomei, C. Alduino, S. Zimmermann, S. Copello, S. L. Wagaarachchi, Paolo Carniti, Stefano Zucchelli, C. Bucci, B. S. Wang, O. Azzolini, L. Gironi, F. T. Avignone, Silvia Capelli, Massimiliano Nastasi, C. Rosenfeld, P. Gorla, F. Ferroni, Emanuele Ferri, Monica Sisti, C. J. Davis, A. Camacho, Maria Laura Di Vacri, B. Schmidt, A. Caminata, M. Pavan, Sergio Di Domizio, A. D'Addabbo, S. J. Freedman, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Novati, V, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Dell'Oro, S, Deninno, M, Di Domizio, S, Di Vacri, M, Dompe, V, Drobizhev, A, Fang, D, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Hennings-Yeomans, R, Huang, H, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Ma, Y, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Nagorny, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, N, Singh, V, Sisti, M, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zhang, G, Zimmermann, S, and Zucchelli, S

Subjects
7. Clean energy, law.invention, crystal, Nuclear physics, CUORE, bolometer, double-beta decay: (0neutrino), law, Double beta decay, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Cherenkov, Sensitivity (control systems), talk: Uppsala 2017/09/25, Cherenkov radiation, scintillation counter, Physics, lifetime, Scintillation, background, Bolometer, sensitivity, Upgrade, cryogenics, Neutrinoless Double Beta Decay, Cryogenic detector, Scintillating bolometer, Scintillation counter, upgrade, upper limit, experimental results
Abstract

International audience; CUORE is the first bolometric tonne-scale experiment aiming at the investigation of neutrinoless double-beta (0$\nu$2$\beta$) decay of $^{130}$Te. The cryogenic commissioning followed by the detector installation and cool down took place during 2016. After the optimisation of all the detectors, the data-taking started in spring 2017. We report about the results of the first dataset acquired in May, which led to a limit on the 0$\nu$2$\beta$ half-life of $^{130}$Te of 6.6$\times$10$^{24}$ yr. An upgrade of CUORE, named CUPID, is planned to improve the 0$\nu$2$\beta$-decay sensitivity via passive and active background reduction and crystal enrichment. Some technologies for CUPID are currently under study and two of them are presented here, involving the detection of Cherenkov and scintillation light emitted by enriched $^{130}$TeO$_2$ and Li$^{100}_2$MoO$_4$ crystals respectively. This will allow us to reject the currently dominant a background.

Published
2017
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17. Initial performance of the CUORE detector

Author

D. Santone, L. Zanotti, Carlo Ligi, Ettore Fiorini, L. Gladstone, N. Chott, K. Wilson, H. Z. Huang, Lorenzo Cassina, T. Wise, C. Pagliarone, M. Faverzani, G. Keppel, K. E. Lim, N. D. Scielzo, Stuart Freedman, R. J. Creswick, A. Drobizhev, Jonathan Ouellet, G. Bari, K. Alfonso, M. L. Di Vacri, Davide Chiesa, L. Canonica, Y. Mei, M. A. Franceschi, B. Schmidt, L. Marini, L. Taffarello, Monica Sisti, H. W. Wang, L. Gironi, F. T. Avignone, T. O'Donnell, B. S. Wang, A. Bersani, A. Giuliani, Virendra Singh, O. Azzolini, S. Morganti, M. Sakai, S. Copello, M. Pavan, Y. G. Ma, M. M. Deninno, S. S. Nagorny, Paolo Carniti, Xi-Guang Cao, K. M. Heeger, S. Zimmermann, C. Pira, I. Dafinei, John Wilson, Claudio Gotti, F. Bellini, V. Palmieri, N. Moggi, C. Rosenfeld, V. Novati, Silvia Capelli, Samuele Sangiorgio, S. L. Wagaarachchi, Massimiliano Nastasi, S. Zucchelli, A. Nucciotti, Lindley Winslow, Eric B. Norman, C. Alduino, Oliviero Cremonesi, A. Giachero, A. D'Addabbo, Guoqiang Zhang, T. Napolitano, P. Gorla, F. Ferroni, C. Tomei, Stefano Dell'Oro, S. Pirro, C. Bucci, T. D. Gutierrez, Miriam Lucio Martinez, D. Q. Fang, Yu. G. Kolomensky, Luigi Cappelli, Jeremy S. Cushman, Emanuele Ferri, M. Biassoni, N. Casali, D. D'Aguanno, C. J. Davis, F. Reindl, Ke Han, A. Branca, Reina H. Maruyama, L. Pattavina, Giovanni Benato, Irene Nutini, A. Camacho, J. Schmidt, C. Nones, R. Hennings-Yeomans, S. Di Domizio, F. Terranova, A. Caminata, Ezio Previtali, B. Welliver, Laura Cardani, Marco Pallavicini, B. K. Fujikawa, Massimiliano Clemenza, Stefano Pozzi, Carlo Cosmelli, G. Pessina, M. Vignati, C. Brofferio, C. Rusconi, A. Leder, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Département de Physique des Particules (ex SPP) (DPhP), Cushman, J, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Dell'Oro, S, Deninno, M, Domizio, S, Vacri, M, Drobizhev, A, Fang, D, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Hennings-Yeomans, R, Huang, H, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Ma, Y, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Nagorny, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, N, Singh, V, Sisti, M, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zhang, G, Zimmermann, S, and Zucchelli, S

Subjects
Cryostat, History, Cryogenics, 01 natural sciences, tellurium: oxygen, Neutrinoless Double Beta Decay, Cryogenic detector, bolometer, Education, law.invention, Nuclear physics, CUORE, double-beta decay: (0neutrino), Observatory, law, Double beta decay, 0103 physical sciences, Calibration, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, activity report, Physics, 010308 nuclear & particles physics, Detector, Bolometer, calibration, Computer Science Applications, cryogenics, tellurium: nuclide, performance
Abstract

CUORE, the Cryogenic Underground Observatory for Rare Events, is an experiment searching for the neutrinoless double-beta decay of 130Te. The first CUORE dataset was acquired in May and June 2017 and consisted of 10.6 kg-yr of TeO2 exposure, with several days of calibration data before and after the physics dataset. We discuss here the initial performance of the CUORE detector and cryostat in this first dataset.

Published
2017
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18. First results from the CUORE experiment

Author

M. Faverzani, N. Casali, A. Bersani, C. Nones, Davide Chiesa, Ettore Fiorini, S. L. Wagaarachchi, C. Rosenfeld, K. Wilson, S. S. Nagorny, F. Reindl, C. Bucci, T. D. Gutierrez, Miriam Lucio Martinez, P. Gorla, F. Ferroni, A. Giuliani, C. Tomei, Jonathan Ouellet, Andrea Giachero, Guoqiang Zhang, G. Bari, Emanuele Ferri, Yu. G. Kolomensky, N. Chott, T. Wise, Marco Pallavicini, S. Di Domizio, J. Schmidt, C. J. Davis, A. Camacho, Jeremy S. Cushman, L. Gladstone, H. Z. Huang, Lindley Winslow, S. Morganti, C. Pagliarone, L. Gironi, Laura Cardani, Carlo Cosmelli, L. Taffarello, B. K. Fujikawa, G. Pessina, G. Keppel, K. E. Lim, F. T. Avignone, Monica Sisti, Stefano Pozzi, Carlo Ligi, Giovanni Benato, Ke Han, A. Branca, Reina H. Maruyama, Virendra Singh, K. Alfonso, Stuart J. Freedman, N. Moggi, Lorenzo Cassina, M. L. Di Vacri, V. Palmieri, S. Zucchelli, C. Pira, Samuele Sangiorgio, A. Drobizhev, S. Zimmermann, Eric B. Norman, N. D. Scielzo, M. Vignati, A. Nucciotti, L. Pattavina, B. Schmidt, T. Napolitano, F. Terranova, Stefano Dell'Oro, C. Alduino, R. J. Creswick, B. S. Wang, M. Clemenza, Claudio Gotti, V. Novati, Silvia Capelli, Massimiliano Nastasi, O. Azzolini, C. Brofferio, V. Dompè, M. Biassoni, A. D'Addabbo, Y. Mei, C. Rusconi, I. Dafinei, John Wilson, H. W. Wang, M. Sakai, T. O'Donnell, Xi-Guang Cao, M. A. Franceschi, K. M. Heeger, Oliviero Cremonesi, S. Copello, A. Caminata, Ezio Previtali, Paolo Carniti, B. Welliver, M. M. Deninno, M. Pavan, Y. G. Ma, Irene Nutini, F. Bellini, R. Hennings-Yeomans, L. Cappelli, Stefano Pirro, D. D'Aguanno, D. Q. Fang, L. Canonica, L. Marini, A. Leder, D. Santone, L. Zanotti, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Dell'Oro, S, Deninno, M, Domizio, S, Vacri, M, Dompe, V, Drobizhev, A, Fang, D, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Hennings-Yeomans, R, Huang, H, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Ma, Y, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Nagorny, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, N, Singh, V, Sisti, M, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zhang, G, Zimmermann, S, Zucchelli, S, and Département de Physique des Particules (ex SPP) (DPhP)

Subjects
History, Cryogenic system, hierarchy, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 01 natural sciences, 030218 nuclear medicine & medical imaging, Education, Neutrinoless Double Beta Decay, Cryogenic detector, bolometer, Combinatorics, decoupling, 03 medical and health sciences, 0302 clinical medicine, CUORE, double-beta decay: (0neutrino), bolometer, Double beta decay, tellurium, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Physics, lifetime, 010308 nuclear & particles physics, temperature, sensitivity, Double beta decay - Cryogenic equipment - Majorana neutrino, Computer Science Applications, talk: Sudbury 2017/07/24, observatory, cryogenics, mass: Majorana, experimental results
Abstract

Author(s): Alduino, C; Alfonso, K; Avignone, FT; Azzolini, O; Bari, G; Bellini, F; Benato, G; Bersani, A; Biassoni, M; Branca, A; Brofferio, C; Bucci, C; Camacho, A; Caminata, A; Canonica, L; Cao, XG; Capelli, S; Cappelli, L; Cardani, L; Carniti, P; Casali, N; Cassina, L; Chiesa, D; Chott, N; Clemenza, M; Copello, S; Cosmelli, C; Cremonesi, O; Creswick, RJ; Cushman, JS; D'Addabbo, A; D'Aguanno, D; Dafinei, I; Davis, CJ; Dell'Oro, S; Deninno, MM; Domizio, SD; Vacri, MLD; Dompe, V; Drobizhev, A; Fang, DQ; Faverzani, M; Ferri, E; Ferroni, F; Fiorini, E; Franceschi, MA; Freedman, SJ; Fujikawa, BK; Giachero, A; Gironi, L; Giuliani, A; Gladstone, L; Gorla, P; Gotti, C; Gutierrez, TD; Han, K; Heeger, KM; Hennings-Yeomans, R; Huang, HZ; Keppel, G; Kolomensky, YG; Leder, A; Ligi, C; Lim, KE; Ma, YG; Marini, L; Martinez, M; Maruyama, RH; Mei, Y; Moggi, N; Morganti, S; Nagorny, SS; Napolitano, T; Nastasi, M; Nones, C; Norman, EB; Novati, V; Nucciotti, A; Nutini, I; O'Donnell, T; Ouellet, JL; Pagliarone, CE; Pallavicini, M; Palmieri, V; Pattavina, L | Abstract: CUORE (Cryogenic Underground Observatory for Rare Events) is a ton-scale experiment aiming to the search of neutrino-less double beta decay in 130Te with a projected sensitivity on the Majorana effective mass close to the inverted hierarchy region. The CUORE detector consists of a segmented array of 988 TeO2 bolometers, organized in 19 towers and operated at a temperature of about 10 mK thanks to a custom cryogenic system which, besides the uncommon scale, observes several constraints from the radio-purity of the materials to the mechanical decoupling of the cooling systems. The successful commissioning of the CUORE cryogenic system has been completed early in 2016 and represents an outstanding achievement by itself. The installation of the detector proceeded along 2016 followed by the cooldown to base temperature at the beginning of 2017. The CUORE detector is now operational and has been taking science data since Spring 2017. With the first ∼3 weeks of collected data, we present here the most stringent constraint on the 130Te half-live for the neutrino-less double beta decay.

Published
2017
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19. Clcn7

Author

J, Caetano-Lopes, S G, Lessard, S, Hann, K, Espinoza, K S, Kang, K E, Lim, D J, Horan, H R, Noonan, D, Hu, R, Baron, A G, Robling, and M L, Warman

Subjects
Heterozygote, Homozygote, Osteoclasts, Cell Count, Organ Size, Bone and Bones, Article, Disease Models, Animal, Interferon-gamma, Mice, Phenotype, Chloride Channels, Loss of Function Mutation, Osteopetrosis, Cancellous Bone, Animals, Gene Knock-In Techniques, Alleles, Genes, Dominant
Abstract

Dominant negative mutations in CLCN7, which encodes a homodimeric chloride channel needed for matrix acidification by osteoclasts, cause Albers-Schönberg disease (also known as autosomal dominant osteopetrosis type 2). More than 25 different CLCN7 mutations have been identified in patients affected with Albers-Schönberg disease, but only one mutation (Clcn7G213R) has been introduced in mice to create an animal model of this disease. Here we describe a mouse with a different osteopetrosis-causing mutation (Clcn7F318L). Compared to Clcn7+/+ mice, 12-week-old Clcn7F318L/+ mice have significantly increased trabecular bone volume, consistent with Clcn7F318L acting as a dominant negative mutation. Clcn7F318L/F318L and Clcn7F318L/G213R mice die by 1 month of age and resemble Clcn7 knockout mice, which indicate that p.F318L mutant protein is non-functional and p.F318L and p.G213R mutant proteins do not complement one another. Since it has been reported that treatment with interferon gamma (IFN-G) improves bone properties in Clcn7G213R/+ mice, we treated Clcn7F318L/+ mice with IFN-G and observed a decrease in osteoclast number and mineral apposition rate, but no overall improvement in bone properties. Our results suggest that the benefits of IFN-G therapy in patients with Albers-Schönberg disease may be mutation-specific.

Published
2017

20. Analysis of the XENON100 dark matter search data

Author

S. E. A. Orrigo, Marc Schumann, P. Shagin, J. A. M. Lopes, A. Kish, Luke Goetzke, Jean-Pierre Cussonneau, K. E. Lim, Elena Aprile, E. Nativ, W. Hampel, M. Selvi, Ehud Duchovni, K. Bokeloh, E. K. U. Gross, João Cardoso, Hui Wang, Uwe Oberlack, Jochen Schreiner, M. Weber, F. Gao, A. Behrens, T. Marrodán Undagoitia, F. V. Massoli, Qing Lin, M. Le Calloch, J.M.F. dos Santos, O. Vitells, Ch. Weinheimer, A. Rizzo, P. Beltrame, W. Fulgione, N. Priel, C. Grignon, A. J. Melgarejo Fernandez, A. Teymourian, M. Garbini, K. Arisaka, S. Rosendahl, Sebastian Lindemann, M. Alfonsi, F. Arneodo, W. T. Chen, Ran Budnik, Kaixuan Ni, R. Persiani, Karl Giboni, David B. Cline, G. Sartorelli, Laura Baudis, C. Balan, Giacomo Bruno, Hardy Simgen, A. D. Ferella, H. Contreras, E. Pantic, K. Lung, Ethan Brown, M. P. Decowski, Manfred Lindner, Y. Mei, P. R. Scovell, Guillaume Plante, Y. Meng, A. Molinario, S. Fattori, C. Levy, B. Choi, D. Thers, R. F. Lang, J. Lamblin, H. Landsman, L. Scotto Lavina, The XENON100 Collaboration, Astroparticle Physics (IHEF, IoP, FNWI), Aprile, E., Alfonsi, M., Arisaka, K., Arneodo, F., Balan, C., Baudis, L., Behrens, A., Beltrame, P., Bokeloh, K., Brown, E., Bruno, G., Budnik, R., Cardoso, J.M.R., Chen, W.-T., Choi, B., Cline, D.B., Contreras, H., Cussonneau, J.P., Decowski, M.P., Duchovni, E., Fattori, S., Ferella, A.D., Fulgione, W., Gao, F., Garbini, M., Giboni, K.-L., Goetzke, L.W., Grignon, C., Gross, E., Hampel, W., Kish, A., Lamblin, J., Landsman, H., Lang, R.F., Le Calloch, M., Levy, C., Lim, K.E., Lin, Q., Lindemann, S., Lindner, M., Lopes, J.A.M., Lung, K., Marrodán Undagoitia, T., Massoli, F.V., Mei, Y., Melgarejo Fernandez, A.J., Meng, Y., Molinario, A., Nativ, E., Ni, K., Oberlack, U., Orrigo, S.E.A., Pantic, E., Persiani, R., Plante, G., Priel, N., Rizzo, A., Rosendahl, S., Dos Santos, J.M.F., Sartorelli, G., Schreiner, J., Schumann, M., Scotto Lavina, L., Scovell, P.R., Selvi, M., Shagin, P., Simgen, H., Teymourian, A., Thers, D., Vitells, O., Wang, H., Weber, M., and Weinheimer, C.

Subjects
Large Underground Xenon experiment, Physics - Instrumentation and Detectors, Xenon, WIMP, Physics::Instrumentation and Detectors, Direct detection, Dark matter, chemistry.chemical_element, FOS: Physical sciences, DarkSide, WIMP Argon Programme, Nuclear physics, Statistical analysis, Nuclear Experiment, Instrumentation and Methods for Astrophysics (astro-ph.IM), Physics, Time projection chamber, Astrophysics::Instrumentation and Methods for Astrophysics, Astronomy and Astrophysics, Instrumentation and Detectors (physics.ins-det), WIMPs, chemistry, Weakly interacting massive particles, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

The XENON100 experiment, situated in the Laboratori Nazionali del Gran Sasso, aims at the direct detection of dark matter in the form of weakly interacting massive particles (WIMPs), based on their interactions with xenon nuclei in an ultra low background dual-phase time projection chamber. This paper describes the general methods developed for the analysis of the XENON100 data. These methods have been used in the 100.9 and 224.6 live days science runs from which results on spin-independent elastic, spin-dependent elastic and inelastic WIMP-nucleon cross-sections have already been reported., Comment: 18 pages, 17 figures, information for the 224.6 live days run included

Published
2014
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21. Results from CUORE and CUORE-0

Author

C. Rosenfeld, P. Gorla, F. Ferroni, C. Tomei, Emanuele Ferri, H. W. Wang, C. J. Davis, A. Camacho, Carlo Ligi, S. J. Freedman, M. M. Deninno, H. Z. Huang, N. D. Scielzo, E. Fiorini, N. Moggi, Massimiliano Clemenza, Lucia Canonica, Yu. G. Kolomensky, Luigi Cappelli, C. Pagliarone, S. S. Nagorny, Monica Sisti, F. Bellini, Samuele Sangiorgio, R. Hennings-Yeomans, S. Pozzi, Oliviero Cremonesi, S. Zimmermann, A. Nucciotti, B. Schmidt, A. Caminata, C. Alduino, M. Faverzani, T. Wise, R. J. Creswick, K. Alfonso, C. Bucci, Miriam Lucio Martinez, Marco Pallavicini, L. Pattavina, A. Woodcraft, Lindley Winslow, Jonathan Ouellet, B. Welliver, M. L. Di Vacri, G. Pessina, G. Bari, L. Taffarello, C. Brofferio, P. J. Mosteiro, Guimin Zhang, L. Gironi, F. T. Avignone, Lorenzo Cassina, V. Singh, S. L. Wagaarachchi, Giovanni Benato, C. Pira, N. Casali, C. Cosmelli, C. Nones, V. Palmieri, T. D. Gutierrez, E. Previtali, F. Terranova, C. Rusconi, Eric B. Norman, A. D'Addabbo, M. Sakai, T. Napolitano, Simone Capelli, N. Chott, L. Marini, V. Novati, D. D'Aguanno, M. Biassoni, S. Copello, S. Morganti, Paolo Carniti, Ke Han, A. Branca, Reina H. Maruyama, Y. Mei, Stefano Dell'Oro, Stefano Zucchelli, Xi-Guang Cao, K. M. Heeger, J. Schmidt, T. O'Donnell, Yu-Gang Ma, G. Keppel, D. R. Artusa, M. Pavan, Massimiliano Nastasi, A. Giuliani, A. Bersani, I. Dafinei, Davide Chiesa, K. E. Lim, Jeremy S. Cushman, L. Zanotti, A. Leder, A. Drobizhev, D. Santone, J. S. Wilson, B. S. Wang, O. Azzolini, M. A. Franceschi, C. Gotti, A. Giachero, D. Q. Fang, L. Gladstone, S. Pirro, S. Di Domizio, Laura Cardani, B. K. Fujikawa, M. Vignati, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPhP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Département de Physique des Particules (ex SPP) (DPP), Moggi, N, Alduino, C, Alfonso, K, Artusa, D, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Dell'Oro, S, Deninno, M, Di Domizio, S, Di Vacri, M, Drobizhev, A, Fang, D, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Hennings-Yeomans, R, Huang, H, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Ma, Y, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Morganti, S, Mosteiro, P, Nagorny, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Novati, V, Nucciotti, A, O'Donnell, T, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, N, Singh, V, Sisti, M, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Welliver, B, Wilson, J, Winslow, L, Wise, T, Woodcraft, A, Zanotti, L, Zhang, G, Zimmermann, S, Zucchelli, S, Moggi, N., Alduino, C., Alfonso, K., Artusa, D. R., Avignone, F. T., Azzolini, O., Bari, G., Bellini, F., Benato, G., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., A., Camacho, Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., D'Aguanno, D., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Han, K., Heeger, K. M., Hennings-Yeomans, R., Huang, H. Z., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Ma, Y. G., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Morganti, S., Mosteiro, P. J., Nagorny, S. S., Napolitano, T., Nastasi, M., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., O'Donnell, T., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sakai, M., Sangiorgio, S., Santone, D., Schmidt, B., Schmidt, J., Scielzo, N. D., Singh, V., Sisti, M., Taffarello, L., Terranova, F., Tomei, C., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Welliver, B., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., S., Zimmermann, Zucchelli, S., and Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11)

Subjects
Cryostat, Particle physics, detector: performance, Physics::Instrumentation and Detectors, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 01 natural sciences, 7. Clean energy, tellurium: oxygen, law.invention, Physics and Astronomy (all), CUORE, background: low, Contamination, double-beta decay: (0neutrino), bolometer, Observatory, law, Double beta decay, Validation, 0103 physical sciences, Neutrino Physics, 010306 general physics, Double Beta Decay, Particle Physics, Physics, Neutrino Physics, Double Beta Decay, Particle Physics, 010308 nuclear & particles physics, Bolometer, Detector, observatory, cryogenics, High Energy Physics::Experiment, tellurium: nuclide, experimental results
Abstract

International audience; The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta decay that has been able to reach the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. The construction of the experiment and the installation of all towers in the cryostat was completed in August 2016: the experiment is now in data taking phase. In this talk, beyond updating the physics results from CUORE-0, we will discuss the achievements and technical challenges of the CUORE construction phase, with particular emphasis on the background reduction strategy, the performance of the detector during pre-operation and the projected first results from the full detector run.

Published
2017
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22. CUORE sensitivity to $0\nu \beta \beta $ decay

Author

L. Gladstone, T. I. Banks, James R. Wilson, D. R. Artusa, Vasundhara Singh, R. J. Creswick, Monica Sisti, M. Faverzani, B. Schmidt, B. S. Wang, Ettore Fiorini, S. Copello, K. Alfonso, M. L. Di Vacri, Lindley Winslow, C. Bucci, T. D. Gutierrez, O. Azzolini, Paolo Carniti, A. Bersani, L. Zanotti, G. Piperno, Claudio Gotti, L. Pattavina, M. M. Deninno, A. D'Addabbo, Stefano Dell'Oro, Guimin Zhang, Jeremy S. Cushman, M. Maino, Massimiliano Nastasi, L. Gironi, S. L. Wagaarachchi, E. V. Hansen, N. Casali, F. T. Avignone, H. W. Wang, F. Bellini, S. Zimmermann, S. Pirro, Carlo Ligi, Simone Capelli, R. W. Kadel, T. O'Donnell, M. Tenconi, C. Pira, S. Trentalange, A. Leder, C. Pagliarone, N. Moggi, T. Wise, M. Pavan, Oliviero Cremonesi, H. Z. Huang, G. Keppel, Davide Chiesa, C. Rosenfeld, D. Santone, Samuele Sangiorgio, K. E. Lim, Ioan Dafinei, C. Nones, P. Gorla, A. Nucciotti, F. Ferroni, Jeffrey W. Beeman, C. Tomei, C. Alduino, B. X. Zhu, V. Novati, V. Pettinacci, Emanuele Ferri, Eugene E. Haller, S. Morganti, M. I. Martínez, Nicholas Scielzo, A. Giuliani, G. Fernandes, A. Camacho, N. Chott, Alan R. Smith, C. J. Davis, Marco Pallavicini, G. Pessina, L. Taffarello, Massimiliano Clemenza, Carlo Cosmelli, C. Brofferio, P. J. Mosteiro, C. Rusconi, Y. Mei, M. Sakai, S. Di Domizio, R. Hennings-Yeomans, Xi-Guang Cao, Laura Cardani, K. M. Heeger, B. K. Fujikawa, Stefano Pozzi, A. Drobizhev, M. Vignati, Giovanni Benato, M. A. Franceschi, Ke Han, A. Branca, Reina H. Maruyama, Stuart J. Freedman, S. Zucchelli, A. Woodcraft, V. Palmieri, Eric B. Norman, T. Napolitano, F. Terranova, Jonathan Ouellet, G. Bari, M. Biassoni, A. Giachero, D. Q. Fang, L. Canonica, L. Marini, Kevin Hickerson, Y. G. Ma, J. Schmidt, L. Carbone, Yu. G. Kolomensky, Luigi Cappelli, Lorenzo Cassina, A. Caminata, Ezio Previtali, B. Welliver, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, CUORE, Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre de Sciences Nucléaires et de Sciences de la Matière ( CSNSM ), Université Paris-Sud - Paris 11 ( UP11 ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Département de Physique des Particules (ex SPP) ( DPP ), Institut de Recherches sur les lois Fondamentales de l'Univers ( IRFU ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay, and Département de Physique des Particules (ex SPP) (DPhP)

Subjects
Particle physics, Physics - Instrumentation and Detectors, Physics and Astronomy (miscellaneous), Data division, energy resolution, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 01 natural sciences, statistics: Bayesian, CUORE, double-beta decay: (0neutrino), Double beta decay, 0103 physical sciences, Beta (velocity), Sensitivity (control systems), [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], [ PHYS.NEXP ] Physics [physics]/Nuclear Experiment [nucl-ex], 010306 general physics, Nuclear Experiment, Engineering (miscellaneous), [ PHYS.PHYS.PHYS-INS-DET ] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Physics, 010308 nuclear & particles physics, background, sensitivity, Beta decay, Background level, numerical calculations: Monte Carlo, Energy (signal processing)
Abstract

We report a study of the CUORE sensitivity to neutrinoless double beta ($0\nu\beta\beta$) decay. We used a Bayesian analysis based on a toy Monte Carlo (MC) approach to extract the exclusion sensitivity to the $0\nu\beta\beta$ decay half-life ($T_{1/2}^{0\nu}$) at $90\%$ credibility interval (CI) -- i.e. the interval containing the true value of $T_{1/2}^{0\nu}$ with $90\%$ probability -- and the $3 \sigma$ discovery sensitivity. We consider various background levels and energy resolutions, and describe the influence of the data division in subsets with different background levels. If the background level and the energy resolution meet the expectation, CUORE will reach a $90\%$ CI exclusion sensitivity of $2\cdot10^{25}$ yr with $3$ months, and $9\cdot10^{25}$ yr with $5$ years of live time. Under the same conditions, the discovery sensitivity after $3$ months and $5$ years will be $7\cdot10^{24}$ yr and $4\cdot10^{25}$ yr, respectively., Comment: 10 pages, 3 figures, 4 tables

Published
2017
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23. The State of ESKAPE in Malaysia

Author

V. K. E. Lim, Soo-Sum Lean, Hannah C. McNeil, and Stuart C. Clarke

Subjects
0301 basic medicine, Microbiology (medical), Cross Infection, business.industry, 030106 microbiology, Malaysia, General Medicine, State (functional analysis), Gram-Positive Bacteria, 03 medical and health sciences, Infectious Diseases, Drug Resistance, Multiple, Bacterial, Gram-Negative Bacteria, Prevalence, Medicine, Humans, Pharmacology (medical), Economic system, business, Gram-Negative Bacterial Infections, Gram-Positive Bacterial Infections
Published
2016

24. The Cryogenic Underground Observatory for Rare Events: Status and Prospects

Author

L. Cardani, Massimiliano Clemenza, Carlo Cosmelli, Y. Mei, K. M. Heeger, L. Gladstone, A. Bersani, N. Moggi, A. Woodcraft, Lorenzo Cassina, Ke Han, A. Branca, Reina H. Maruyama, Stuart J. Freedman, F. Terranova, N. Casali, Samuele Sangiorgio, A. Nucciotti, R. J. Creswick, Marco Pallavicini, C. Alduino, L. Zanotti, G. Piperno, G. Pessina, M. Faverzani, C. Brofferio, P. J. Mosteiro, Carlo Ligi, Yu-Gang Ma, Jeremy S. Cushman, M. Pavan, Oliviero Cremonesi, A. R. Smith, A. Caminata, Xu Cao, C. Nones, M. M. Deninno, I. Dafinei, E. Previtali, L. Canonica, A. Drobizhev, Davide Chiesa, K. E. Lim, S. Zucchelli, L. Marini, Kevin Hickerson, M. Tenconi, M. A. Franceschi, S. Morganti, R. Hennings-Yeomans, A. Giachero, V. Palmieri, Jeffrey W. Beeman, G. Fernandes, D. Q. Fang, Yu. G. Kolomensky, Luigi Cappelli, Eric B. Norman, C. Bucci, T. D. Gutierrez, Miriam Lucio Martinez, Jonathan Ouellet, T. Napolitano, A. Leder, N. Chott, G. Bari, L. Pattavina, Claudio Gotti, A. Giuliani, M. Biassoni, L. Carbone, S. Trentalange, D. Santone, C. Pagliarone, H. C. Huang, N. D. Scielzo, James R. Wilson, T. Wise, G. Keppel, D. R. Artusa, Monica Sisti, L. Gironi, S. Zimmermann, B. S. Wang, F. T. Avignone, O. Azzolini, S. Copello, Paolo Carniti, Stefano Dell'Oro, A. D'Addabbo, L. Taffarello, M. Maino, H. W. Wang, T. O'Donnell, Virendra Singh, Ettore Fiorini, C. Rosenfeld, Guimin Zhang, P. Gorla, F. Ferroni, C. Tomei, Emanuele Ferri, Eugene E. Haller, C. Pira, A. Camacho, K. Alfonso, M. L. Di Vacri, E. V. Hansen, T. I. Banks, C. Rusconi, B. X. Zhu, V. Novati, V. Pettinacci, Stefano Pirro, C. J. Davis, S. L. Wagaarachchi, Lindley Winslow, Simone Capelli, R. W. Kadel, F. Bellini, S. Di Domizio, B. K. Fujikawa, Stefano Pozzi, M. Vignati, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Massachusetts Institute of Technology. Department of Physics, Massachusetts Institute of Technology. Department of Nuclear Science and Engineering, and Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11)

Subjects
Physics, CUORE, nucleus, Solar neutrino problem, tellurium: oxygen, Gran Sasso, Nuclear physics, observatory, MAJORANA, talk: Adelaide 2016/09/11, mass: hierarchy, bolometer, double-beta decay: (0neutrino), Observatory, Double-beta decay: (0neutrino) | observatory | neutrino: Majorana | neutrino: mass | mass: hierarchy | Gran Sasso | nucleus | CUORE | tellurium: oxygen | bolometer | experimental results, Double beta decay, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], neutrino: Majorana, Dilution refrigerator, neutrino: mass, Neutrino, Neutrino oscillation, experimental results
Abstract

International audience; The Cryogenic Underground Observatory for Rare Events (CUORE) is a large-scale double beta decay experiment utilizing cryogenic bolometers that is currently being commissioned at the Gran Sasso National Laboratory (LNGS) in Italy. Its primary focus is to search for the neutrinoless double beta decay of 130Te with a projected sensitivity to Majorana neutrino masses near the inverted mass hierarchy region. The detector is composed of 988 5x5x5-cm3 TeO2 crystals of natural isotopic composition arranged in 19 towers of 52 crystals each, all housed in a common dilution refrigerator. A single CUORE-like tower, CUORE-0, was assembled and operated as a stand-alone detector for a period of approximately two years. In this report, the results from CUORE-0 and the current status and physics potential of CUORE are presented.

Published
2016
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25. Status and prospects for CUORE

Author

Claudio Gotti, L. Canonica, L. Marini, Kevin Hickerson, A. D'Addabbo, M. Faverzani, A. Leder, A. Giachero, Lindley Winslow, Jeremy S. Cushman, S. Zimmermann, D. Q. Fang, D. Santone, N. Casali, L. Taffarello, Virendra Singh, Jonathan Ouellet, James R. Wilson, A. Bersani, B. X. Zhu, G. Bari, E. V. Hansen, M. M. Deninno, F T Avignone Iii., C. J. Davis, Guimin Zhang, A. Caminata, G. Keppel, D. R. Artusa, A. Drobizhev, Massimiliano Clemenza, Carlo Cosmelli, I. Dafinei, Monica Sisti, N. D. Scielzo, Ezio Previtali, S. Morganti, L. Gironi, M. A. Franceschi, C. Rusconi, F. Bellini, S. L. Wagaarachchi, Oliviero Cremonesi, L. Carbone, S. Copello, N. Moggi, A. Giuliani, G. Fernandes, F. Orio, L. Gladstone, Samuele Sangiorgio, N. Chott, Yu. G. Kolomensky, Luigi Cappelli, A. Nucciotti, V. Pettinacci, Paolo Carniti, B. S. Wang, L. Cardani, M. L. Di Vacri, C. Alduino, Ke Han, A. Branca, Reina H. Maruyama, L. Zanotti, S. Di Domizio, O. Azzolini, S. Trentalange, Stuart J. Freedman, A. Woodcraft, Carlo Ligi, Lorenzo Cassina, S. Pirro, C. Brofferio, P. J. Mosteiro, Simone Capelli, R. Hennings-Yeomans, B. K. Fujikawa, Stefano Pozzi, M. Pavan, A. R. Smith, Davide Chiesa, R. W. Kadel, R. J. Creswick, F. Terranova, S. Zucchelli, K. E. Lim, Jeffrey W. Beeman, V. Palmieri, M. Vignati, G. Piperno, C. Rosenfeld, Y. Mei, Eric B. Norman, P. Gorla, T. Napolitano, Xi-Guang Cao, F. Ferroni, C. Tomei, Ettore Fiorini, K. M. Heeger, C. Bucci, T. D. Gutierrez, Miriam Lucio Martinez, Emanuele Ferri, Eugene E. Haller, V. Novati, Yu-Gang Ma, M. Biassoni, A. Camacho, M. Maino, K. Alfonso, M. Tenconi, H. W. Wang, T. O'Donnell, Stefano Dell'Oro, X. Liu, C. Pagliarone, T. Wise, H. Z. Huang, L. Pattavina, T. I. Banks, Marco Pallavicini, G. Pessina, C. Nones, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Canonica, L., Alduino, C., Alfonso, K., Artusa, D. R., Avignone, F. T., Azzolini, O., Banks, T. I., Bari, G., Beeman, J. W., Bellini, F., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., A., Camacho, Caminata, A., Cao, X. G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., G., Fernande, Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Liu, X., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Napolitano, T., Nones, C., Norman, E. B., Novati, V., Nucciotti, A., O'Donnell, T., Orio, F., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Piperno, G., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sangiorgio, S., Santone, D., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Trentalange, S., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zhu, B. X., S., Zimmermann, Zucchelli, S., Département de Physique des Particules (ex SPP) (DPhP), Canonica, L, Alduino, C, Alfonso, K, Artusa, D, Avignone, F, Azzolini, O, Banks, T, Bari, G, Beeman, J, Bellini, F, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Cao, X, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D'Addabbo, A, Dafinei, I, Davis, C, Dell'Oro, S, Deninno, M, Di Domizio, S, Di Vacri, M, Drobizhev, A, Fang, D, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Haller, E, Han, K, Hansen, E, Heeger, K, Hennings-Yeomans, R, Hickerson, K, Huang, H, Kadel, R, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Liu, X, Ma, Y, Maino, M, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Mosteiro, P, Napolitano, T, Nones, C, Norman, E, Novati, V, Nucciotti, A, O'Donnell, T, Orio, F, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sangiorgio, S, Santone, D, Scielzo, N, Singh, V, Sisti, M, Smith, A, Taffarello, L, Tenconi, M, Terranova, F, Tomei, C, Trentalange, S, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Wilson, J, Winslow, L, Wise, T, Woodcraft, A, Zanotti, L, Zhang, G, Zhu, B, Zimmermann, S, Zucchelli, S, and Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11)

Subjects
Physics, History, CUORE, 010308 nuclear & particles physics, energy resolution, double beta decay, sensitivity, 01 natural sciences, Computer Science Applications, Education, Nuclear physics, Physics and Astronomy (all), double-beta decay: (0neutrino), cryogenics, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Activity report | double-beta decay: (0neutrino) | cryogenics | CUORE | energy resolution | sensitivity, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], cryogenic, 010306 general physics, Humanities, activity report
Abstract

Author(s): Canonica, L; Alduino, C; Alfonso, K; Artusa, DR; Avignone, FT; Azzolini, O; Banks, TI; Bari, G; Beeman, JW; Bellini, F; Bersani, A; Biassoni, M; Branca, A; Brofferio, C; Bucci, C; Camacho, A; Caminata, A; Cao, XG; Capelli, S; Cappelli, L; Carbone, L; Cardani, L; Carniti, P; Casali, N; Cassina, L; Chiesa, D; Chott, N; Clemenza, M; Copello, S; Cosmelli, C; Cremonesi, O; Creswick, RJ; Cushman, JS; D'Addabbo, A; Dafinei, I; Davis, CJ; Dell'Oro, S; Deninno, MM; Di Domizio, S; Di Vacri, ML; Drobizhev, A; Fang, DQ; Faverzani, M; Fernandes, G; Ferri, E; Ferroni, F; Fiorini, E; Franceschi, MA; Freedman, SJ; Fujikawa, BK; Giachero, A; Gironi, L; Giuliani, A; Gladstone, L; Gorla, P; Gotti, C; Gutierrez, TD; Haller, EE; Han, K; Hansen, E; Heeger, KM; Hennings-Yeomans, R; Hickerson, KP; Huang, HZ; Kadel, R; Keppel, G; Kolomensky, YG; Leder, A; Ligi, C; Lim, KE; Liu, X; Ma, YG; Maino, M; Marini, L; Martinez, M; Maruyama, RH; Mei, Y; Moggi, N; Morganti, S; Mosteiro, PJ; Napolitano, T; Nones, C; Norman, EB; Novati, V; Nucciotti, A | Abstract: CUORE is a cryogenic detector consisting of 988 TeO2 crystals, 750 g each, and will be operated at a temperature of ∼10 mK, to search for neutrinoless double beta decay (0νββ) of 130Te. The detector, in the final stages of construction at the Laboratori Nazionali del Gran Sasso (Italy), will start its operations in 2016. CUORE-0, its pilot experiment, has proven the feasibility of CUORE, demonstrating that the target background of 0.01 counts/keV/kg/y and the energy resolution of 5 keV are within reach. CUORE-0 also made the most precise measurement of the 2νββ decay. The expected sensitivity of CUORE to the 0νββ 130Te half-life is 9 •1025y, for 5 years of data taking. Here, we report the most recent results of CUORE-0, their implications for CUORE, and the current status of the CUORE experiment.

Published
2016
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26. Analysis techniques for the evaluation of the neutrinoless double-βdecay lifetime inTe130with the CUORE-0 detector

Author

L. Marini, N. Casali, C. Bucci, T. D. Gutierrez, M. Tenconi, M. Pavan, D. Santone, K. Alfonso, R. Hennings-Yeomans, A. Caminata, Marco Pallavicini, S. Zucchelli, L. Pattavina, Ioan Dafinei, Oliviero Cremonesi, Alan R. Smith, G. Fernandes, G. Pessina, M. Faverzani, L. Zanotti, Massimiliano Clemenza, Monica Sisti, C. Rosenfeld, L. Gladstone, A. Bersani, L. Cardani, Jonathan Ouellet, E. Previtali, P. Gorla, F. Ferroni, C. Tomei, L. Carbone, A. Woodcraft, C. Pagliarone, A. Giuliani, G. Bari, Stuart Freedman, R. J. Creswick, V. Palmieri, T. I. Banks, Eugene E. Haller, C. Brofferio, P. J. Mosteiro, S. L. Wagaarachchi, M. I. Martínez, S. Pozzi, L. Gironi, Eric B. Norman, F. T. Avignone, A. Dally, S. Zimmermann, Evelyn Ferri, James R. Wilson, Silvio Morganti, Jeremy S. Cushman, C. J. Davis, S. Di Domizio, Nicholas Scielzo, F. Terranova, S. Trentalange, D. R. Artusa, K. P. Hickerson, B. K. Fujikawa, G. Ventura, N. Moggi, G. Piperno, Liu Xt, M. M. Deninno, C. Gotti, M. Biassoni, T. Wise, A. Giachero, Lucia Canonica, Yinina Ma, M. Vignati, D. Q. Fang, N. Chott, Samuele Sangiorgio, A. Nucciotti, B. X. Zhu, F. Bellini, Davide Chiesa, K. E. Lim, Lorenzo Cassina, L. Taffarello, Ke Han, C. Nones, C. Alduino, S. Pirro, Jeffrey W. Beeman, Reina H. Maruyama, H. W. Wang, A. Drobizhev, T. O'Donnell, Elena Sala, Guimin Zhang, Y. Mei, Stefano Dell'Oro, F. Orio, Vasundhara Singh, Xi-Guang Cao, K. M. Heeger, Luigi Cappelli, H. Z. Huang, B. S. Wang, O. Azzolini, Yu G. Kolomensky, C. Cosmelli, Simone Capelli, R. W. Kadel, E. Fiorini, M. L. Di Vacri, S. Copello, Paolo Carniti, G. Keppel, Lindley Winslow, M. Maino, E. V. Hansen, C. Rusconi, and V. Pettinacci

Subjects
Physics, 010308 nuclear & particles physics, Detector, Bremsstrahlung, 01 natural sciences, Beta decay, Upper and lower bounds, Nuclear physics, MAJORANA, CUORE, 0103 physical sciences, Beta (velocity), Neutrino, 010306 general physics
Abstract

We describe in detail the methods used to obtain the lower bound on the lifetime of neutrinoless double-beta (0 nu beta beta) decay in Te-130 and the associated limit on the effective Majorana mass of the neutrino using the CUORE-0 detector. CUORE-0 is a bolometric detector array located at the Laboratori Nazionali del Gran Sasso that was designed to validate the background reduction techniques developed for CUORE, a next-generation experiment scheduled to come online in 2016. CUORE-0 is also a competitive 0 nu beta beta decay search in its own right and functions as a platform to further develop the analysis tools and procedures to be used in CUORE. These include data collection, event selection and processing, as well as an evaluation of signal efficiency. In particular, we describe the amplitude evaluation, thermal gain stabilization, energy calibration methods, and the analysis event selection used to create our final 0 nu beta beta search spectrum. We define our high level analysis procedures, with emphasis on the new insights gained and challenges encountered. We outline in detail our fitting methods near the hypothesized 0 nu beta beta decay peak and catalog the main sources of systematic uncertainty. Finally, we derive the 0 nu beta beta decay half-life limits previously reported for CUORE-0, T-1/2(0 nu) > 2.7 x 10(24) yr, and in combination with the Cuoricino limit, T-1/2(0 nu) > 4.0 x 10(24) yr.

Published
2016
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27. The Process of Medical Curriculum Development in Malaysia

Author

V. K. E. Lim

Subjects
Medical education, Medical curriculum, business.industry, Process (engineering), education, Medical school, Medicine, Christian ministry, business, Curriculum, humanities, Unit (housing), Accreditation
Abstract

The first medical school established in Malaysia was the Faculty of Medicine at the University of Malaya in 1963 (Danaraj, 1988). Today, there are 33 medical schools, both public and private. All medical schools require accreditation by the National Accreditation Board and the Malaysian Medical Council. These two regulatory bodies set the minimum standards for accreditation and they include standards that pertain to curricular issues. Apart from adhering to major broad principles, medical schools generally are given a free hand in designing and developing their own curricula. The faculty members of the school determine the nature of the curriculum with the dean playing a vital role in moderating competing demands from the various academic departments. The influence of the Medical Education Department or Unit varies. The Ministry of Health, as the predominant employer of doctors, gives regular feedback to the deans on the performance of their graduates. There has not been any major initiative to involve other important stakeholders, including the public, in the design and development of medical curricula in the country.

Published
2012
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28. A practical investigation on nickel plated copper heat spreader with different catalytic activation processes for flip-chip ball grid array packages

Author

Ibrahim Ahmad, Foong Chee Seng, Rozaidi Razid, V. K. E. Lim, and Nowshad Amin

Subjects
Materials science, Mineralogy, Heat sink, Condensed Matter Physics, Thermal diffusivity, Atomic and Molecular Physics, and Optics, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Diffusion layer, Thermal conductivity, Ball grid array, Heat spreader, Water cooling, Electrical and Electronic Engineering, Composite material, Safety, Risk, Reliability and Quality, Flip chip
Abstract

This study investigates the effects of two different catalytic activation techniques on the thermal performance of the flip-chip heat spreaders. The two activation techniques studied are thin nickel–copper strike and galvanic initiation. Thermal diffusivity and surface roughness of these heat spreaders were studied using the Nano-flash Apparatus and Infinite Focus Microscopy. High temperature storage tests were carried out to investigate the extent of intermetallic diffusion between the nickel and copper layers. The results show that heat spreaders with thin nickel–copper strike catalytic activation technique have a lower thermal diffusivity due to the low thermal conductivity of nickel–copper layer. Moreover, the nickel–copper layers grew thicker from around 0.2 μm at initial time to around 0.55 μm after high temperature storage duration of 168 h. On the other hand, heat spreaders processed using the galvanic initiation technique did not form any nickel–copper intermetallic diffusion layer. As a conclusion, the galvanic initiation technique can potentially provide better thermal performance for heat spreaders used in semiconductor packages.

Published
2009
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29. Medical education in Malaysia

Author

V. K. E. Lim

Subjects
Medical education, Physical infrastructure, Kuala lumpur, Education, Medical, business.industry, media_common.quotation_subject, Malaysia, Medical school, MEDLINE, General Medicine, Independence, Accreditation, Education, Physicians, Humans, Medicine, Quality (business), Curriculum, business, Schools, Medical, media_common
Abstract

Malaysia has a long history of medical education, with Singapore becoming the first medical school to serve the region after its foundation in 1905. The first school to be established in Kuala Lumpur after independence from the British was the Faculty of Medicine at the University of Malaya in 1963. Whilst today there are 21 public and private medical schools, all offering a 5 year undergraduate programme, some private schools have diversified by developing international collaboration and conduct twinning or credit-transfer programmes. All medical schools require accreditation by the National Accreditation Board and the Malaysian Medical Council. Although the criteria for accreditation is comprehensive and covers a broad range of areas of assessment, it is debatable whether it always matches the needs of the country. The dramatic increase in medical schools in the last two decades has posed challenges in terms of maintenance of quality, physical infrastructure and suitably qualified faculty.

Published
2008
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30. Measurement of muon annual modulation and muon-induced phosphorescence in NaI(TI) crystals with DM-Ice17

Author

Max Robinson, S. M. Paling, Walter C. Pettus, Liang Yang, J. J. Cherwinka, N. J. C. Spooner, B. N. Reilly, K. E. Lim, P. Sandstrom, K. M. Heeger, L. Hsu, M. Kauer, Albrecht Karle, S. Telfer, Reina H. Maruyama, V. A. Kudryavtsev, A. J. F. Hubbard, Francis Halzen, Calum Michael Macdonald, Darren Grant, and Z. P. Pierpoint

Subjects
Physics, Scintillation, Muon, Photon, Cosmology and Nongalactic Astrophysics (astro-ph.CO), Physics - Instrumentation and Detectors, 010308 nuclear & particles physics, Physics::Instrumentation and Detectors, Dark matter, FOS: Physical sciences, Instrumentation and Detectors (physics.ins-det), 01 natural sciences, High Energy Physics - Experiment, Nuclear physics, Crystal, High Energy Physics - Experiment (hep-ex), Amplitude, 0103 physical sciences, High Energy Physics::Experiment, 010306 general physics, Phosphorescence, Astrophysics - Instrumentation and Methods for Astrophysics, Instrumentation and Methods for Astrophysics (astro-ph.IM), Energy (signal processing), Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We report the measurement of muons and muon-induced phosphorescence in DM-Ice17, a NaI(Tl) direct detection dark matter experiment at the South Pole. Muon interactions in the crystal are identified by their observed pulse shape and large energy depositions. The measured muon rate in DM-Ice17 is 2.93 +/- 0.04 muons/crystal/day with a modulation amplitude of 12.3 +/- 1.7%, consistent with expectation. Following muon interactions, we observe long-lived phosphorescence in the NaI(Tl) crystals with a decay time of 5.5 +/- 0.5 s. The prompt energy deposited by a muon is correlated to the amount of delayed phosphorescence, the brightest of which consist of tens of millions of photons. These photons are distributed over tens of seconds with a rate and arrival timing that do not mimic a scintillation signal above 2 keVee. While the properties of phosphorescence vary among individual crystals, the annually-modulating signal observed by DAMA cannot be accounted for by phosphorescence with the characteristics observed in DM-Ice17., 9 pages, 8 figures

Published
2016

31. Results from the CUORE-0 Experiment

Author

S. Pirro, N. Casali, G. Yu Kolomensky, N. Chott, Davide Chiesa, K. E. Lim, A. Caminata, Jeffrey W. Beeman, S. Zucchelli, Ezio Previtali, A. Bersani, D. Santone, F. Orio, Massimiliano Clemenza, Carlo Cosmelli, H. Z. Huang, C. Pagliarone, T. Wise, A. Dally, M. Tenconi, G. Bari, Claudio Gotti, L. Zanotti, L. Marini, M. L. Di Vacri, Kevin Hickerson, L. Pattavina, M. M. Deninno, B. S. Wang, C. Nones, G. Keppel, D. R. Artusa, Monica Sisti, L. Cappelli, Lucia Canonica, C. Brofferio, P. J. Mosteiro, A. Drobizhev, O. Azzolini, L. Gironi, Ke Han, Reina H. Maruyama, M. Pavan, F. Bellini, F. T. Avignone, S. Copello, L. Gladstone, Oliviero Cremonesi, V. Palmieri, Lorenzo Cassina, G. Piperno, Paolo Carniti, I. Dafinei, John Wilson, R. J. Creswick, Eric B. Norman, R. Hennings-Yeomans, M. I. Martínez, Elena Sala, Y. Mei, C. Rosenfeld, Marco Pallavicini, S. Zimmermann, M. Biassoni, Yu-Gang Ma, N. Moggi, C. Bucci, T. D. Gutierrez, S. Morganti, G. Pessina, P. Gorla, F. Ferroni, C. Tomei, L. Carbone, J. L. Ouellet, Emanuele Ferri, Eugene E. Haller, Samuele Sangiorgio, Xi-Guang Cao, A. Nucciotti, C. Alduino, A. R. Smith, A. Giachero, G. Ventura, K. M. Heeger, S. Trentalange, M. Faverzani, Stefano Dell'Oro, D. Q. Fang, Jeremy S. Cushman, M. Maino, F. Terranova, N. D. Scielzo, H. W. Wang, X. Liu, T. O'Donnell, S. L. Wagaarachchi, A. Giuliani, G. Fernandes, S. Di Domizio, Simone Capelli, R. W. Kadel, B. K. Fujikawa, Stefano Pozzi, Ettore Fiorini, K. Alfonso, M. Vignati, Lindley Winslow, E. V. Hansen, C. Rusconi, V. Pettinacci, L. Cardani, Guimin Zhang, L. Taffarello, Virendra Singh, B. X. Zhu, C. J. Davis, T. I. Banks, Canonica, L, Alduino, C, Alfonso, K, Artusa, D, Avignone, F, Azzolini, O, Banks, T, Bari, G, Beeman, J, Bellini, F, Bersani, A, Biassoni, M, Brofferio, C, Bucci, C, Caminata, A, Cao, X, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, Dafinei, I, Dally, A, Davis, C, Dell'Oro, S, Deninno, M, Di Domizio, S, Di Vacri, M, Drobizhev, A, Fang, D, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Haller, E, Han, K, Hansen, E, Heeger, K, Hennings Yeomans, R, Hickerson, K, Huang, H, Kadel, R, Keppel, G, Yu Kolomensky, G, Lim, K, Liu, X, Ma, Y, Maino, M, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Mosteiro, P, Nones, C, Norman, E, Nucciotti, A, O'Donnell, T, Orio, F, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sala, E, Sangiorgio, S, Santone, D, Scielzo, N, Singh, V, Sisti, M, Smith, A, Taffarello, L, Tenconi, M, Terranova, F, Tomei, C, Trentalange, S, Ventura, G, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Wilson, J, Winslow, L, Wise, T, Zanotti, L, Zhang, G, Zhu, B, Zimmermann, S, Zucchelli, S, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Département de Physique des Particules (ex SPP) (DPhP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay

Subjects
Semileptonic decay, Physics, History, detector: performance, background, neutrino: Majorana: mass, energy resolution, temperature, Astrophysics, bolometer: crystal, Lower limit, tellurium: oxygen, Computer Science Applications, Education, Gran Sasso, Double-beta decay: (0neutrino) | neutrino: Majorana: mass | detector: performance | energy resolution | temperature | background | Gran Sasso | bolometer: crystal | tellurium: oxygen | experimental results, talk: Torino 2015/09/07, Physics and Astronomy (all), CUORE, Effective energy, double-beta decay: (0neutrino), [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], experimental results
Abstract

Author(s): Chiesa, D; Adams, DQ; Alduino, C; Alfonso, K; Avignone, FT; Azzolini, O; Bari, G; Bellini, F; Benato, G; Bersani, A; Biassoni, M; Branca, A; Brofferio, C; Bucci, C; Caminata, A; Campani, A; Canonica, L; Cao, XG; Capelli, S; Cappelli, L; Cardani, L; Carniti, P; Casali, N; Cassina, L; Chott, N; Clemenza, M; Copello, S; Cosmelli, C; Cremonesi, O; Creswick, RJ; Cushman, JS; D'Addabbo, A; D'Aguanno, D; Dafinei, I; Davis, CJ; Dell'Oro, S; Deninno, MM; Di Domizio, S; Dompe, V; Drobizhev, A; Fang, DQ; Faverzani, M; Ferri, E; Ferroni, F; Fiorini, E; Franceschi, MA; Freedman, SJ; Fujikawa, BK; Giachero, A; Gironi, L; Giuliani, A; Gladstone, L; Gorla, P; Gotti, C; Gutierrez, TD; Han, K; Heeger, KM; Hennings-Yeomans, R; Huang, RG; Huang, HZ; Johnston, J; Keppel, G; Kolomensky, YG; Leder, A; Ligi, C; Ma, YG; Marini, L; Martinez, M; Maruyama, RH; Mei, Y; Moggi, N; Morganti, S; Nagorny, SS; Napolitano, T; Nastasi, M; Nones, C; Norman, EB; Novati, V; Nucciotti, A; Nutini, I; O'Donnell, T; Ouellet, JL; Pagliarone, CE; Pallavicini, M; Palmieri, V | Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is the first bolometric experiment searching for neutrinoless double beta (0νββ) decay that has been able to reach the 1-ton scale. The detector consists of an array of 988 TeO2 crystals arranged in a cylindrical compact structure of 19 towers. The construction of the experiment and, in particular, the installation of all towers in the cryostat was completed in 2016 and data taking started in 2017. In this conference we present the 0νββ decay results of CUORE from examining a total TeO2 exposure of 86.3 kg yr, characterized by an effective energy resolution of 7.7 keV FWHM and a background in the region of interest of 0.014 counts/(keV kg yr). Based on these data, CUORE places a lower limit on the 0νββ decay half-life of (90% C.L.). We then discuss the latest updates in the analysis of background and in the evaluation of the half-life of 2νββ decay of 130Te.

Published
2016
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32. Neutrinoless double-beta decay search with CUORE and CUORE-0 experiments

Author

Oliviero Cremonesi, F. Orio, B. S. Wang, O. Azzolini, A. Caminata, Alan R. Smith, C. Pira, L. Pattavina, Nicholas Scielzo, P. Gorla, F. Ferroni, A. Bersani, C. Tomei, Guoqiang Zhang, Emanuele Ferri, N. Casali, Eugene E. Haller, Larissa M. Ejzak, M. M. Deninno, B. X. Zhu, T. I. Banks, S. Pirro, L. Gironi, Ke Han, F. T. Avignone, Reina H. Maruyama, G. Piperno, Stuart J. Freedman, A. Camacho, A. Woodcraft, Jeremy S. Cushman, Lucia Canonica, F. Bellini, D. Santone, Ioan Dafinei, C. Nones, Davide Chiesa, K. E. Lim, M. I. Martínez, Y. L. Li, C. Rosenfeld, V. Palmieri, M. Maino, S. Zucchelli, A. Giuliani, H. Z. Huang, M. Tenconi, N. Moggi, Jeffrey W. Beeman, R. J. Creswick, J. L. Ouellet, F. Terranova, L. Carbone, A. Dally, Eric B. Norman, H. W. Wang, Ezio Previtali, C. Pagliarone, L. Zanotti, Samuele Sangiorgio, Stefano Nisi, Claudio Gotti, S. Trentalange, C. Bucci, T. O'Donnell, H. A. Farach, T. Wise, Silvio Morganti, T. Napolitano, G. Bari, T. D. Gutierrez, A. Nucciotti, Kevin Hickerson, Marco Pallavicini, James R. Wilson, Elena Sala, Y. Mei, M. Faverzani, L. Taffarello, M. Balata, G. Fernandes, G. Pessina, S. Di Domizio, G. Keppel, D. R. Artusa, M. Biassoni, N. Chott, R. Hennings-Yeomans, C. Zarra, Xi-Guang Cao, B. K. Fujikawa, K. M. Heeger, Stefano Pozzi, Monica Sisti, M. Vignati, S. Copello, C. Maiano, D. Q. Fang, A. Drobizhev, D. Orlandi, M. A. Franceschi, G. Ventura, Ettore Fiorini, Andrea Giachero, M. Pavan, Massimiliano Clemenza, Carlo Cosmelli, C. Brofferio, W. D. Tian, M. L. Di Vacri, Simone Capelli, R. W. Kadel, Stefano Dell'Oro, X. Liu, Yu. G. Kolomensky, Luigi Cappelli, Lorenzo Cassina, Carlo Ligi, Vladimir Datskov, Yu-Gang Ma, L. Wielgus, C. Rusconi, Lindley Winslow, X. Z. Cai, V. Pettinacci, L. Cardani, Moggi, N., Artusa, D.R., Avignone, F.T., Azzolini, O., Balata, M., Banks, T.I., Bari, G., Beeman, J., Bellini, F., Bersani, A., Biassoni, M., Brofferio, C., Bucci, C., Cai, X.Z., Camacho, A., Caminata, A., Canonica, L., Cao, X.G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R.J., Cushman, J.S., Dafinei, I., Dally, A., Datskov, V., Dell'Oro, S., Deninno, M.M., Di Domizio, S., Di Vacri, M.L., Drobizhev, A., Ejzak, L., Fang, D.Q., Farach, H.A., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M.A., Freedman, S.J., Fujikawa, B.K., Giachero, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T.D., Haller, E.E., Han, K., Heeger, K.M., Hennings-Yeomans, R., Hickerson, K.P., Huang, H.Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Li, Y.L., Ligi, C., Lim, K.E., Liu, X., Ma, Y.G., Maiano, C., Maino, M., Martinez, M., Maruyama, R.H., Mei, Y., Morganti, S., Napolitano, T., Nisi, S., Nones, C., Norman, E.B., Nucciotti, A., O'Donnell, T., Orio, F., Orlandi, D., Ouellet, J.L., Pagliarone, C.E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sala, E., Sangiorgio, S., Santone, D., Scielzo, N.D., Sisti, M., Smith, A.R., Taffarello, L., Tenconi, M., Terranova, F., Tian, W.D., Tomei, C., Trentalange, S., Ventura, G., Vignati, M., Wang, B.S., Wang, H.W., Wielgus, L., Wilson, J., Winslow, L.A., Wise, T., Woodcraft, A., Zanotti, L., Zarra, C., Zhang, G.Q., Zhu, B.X., Zucchelli, S., European Organization for Nuclear Research (CERN), CSNSM PS1, Centre de Spectrométrie Nucléaire et de Spectrométrie de Masse (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11)-Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Fabbri, F, Giacomelli, P, Moggi, N, Artusa, D, Avignone, F, Azzolini, O, Balata, M, Banks, T, Bari, G, Beeman, J, Bellini, F, Bersani, A, Biassoni, M, Brofferio, C, Bucci, C, Cai, X, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, Dafinei, I, Dally, A, Datskov, V, Dell'Oro, S, Deninno, M, Di Domizio, S, Di Vacri, M, Drobizhev, A, Ejzak, L, Fang, D, Farach, H, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Haller, E, Han, K, Heeger, K, Hennings Yeomans, R, Hickerson, K, Huang, H, Kadel, R, Keppel, G, Kolomensky, Y, Li, Y, Ligi, C, Lim, K, Liu, X, Ma, Y, Maiano, C, Maino, M, Martinez, M, Maruyama, R, Mei, Y, Morganti, S, Napolitano, T, Nisi, S, Nones, C, Norman, E, Nucciotti, A, O'Donnell, T, Orio, F, Orlandi, D, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sala, E, Sangiorgio, S, Santone, D, Scielzo, N, Sisti, M, Smith, A, Taffarello, L, Tenconi, M, Terranova, F, Tian, W, Tomei, C, Trentalange, S, Ventura, G, Vignati, M, Wang, B, Wang, H, Wielgus, L, Wilson, J, Winslow, L, Wise, T, Woodcraft, A, Zanotti, L, Zarra, C, Zhang, G, Zhu, B, and Zucchelli, S

Subjects
Particle physics, QC1-999, double beta decay, 7. Clean energy, 01 natural sciences, law.invention, Nuclear physics, Physics and Astronomy (all). CONTAMINATION, Physics and Astronomy (all), CUORE, bolometer, Observatory, law, Cryogenic Underground Observatory for Rare Events (CUORE), Laboratorio Nazionale del Gran Sasso, Double beta decay, 0103 physical sciences, Mass scale, [PHYS.COND]Physics [physics]/Condensed Matter [cond-mat], 010306 general physics, Physics, [PHYS]Physics [physics], 010308 nuclear & particles physics, BOLOMETERS, Bolometer, CONTAMINATION, MAJORANA, [PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci], Neutrino
Abstract

International audience; The Cryogenic Underground Observatory for Rare Events (CUORE) is an upcoming experiment designed to search for the neutrinoless double-beta decays. Observation of the process would unambiguously establish that neutrinos are Majorana particles and provide information on their absolute mass scale hierarchy. CUORE is now under construction and will consist of an array of 988 TeO2 crystal bolometers operated at 10 mK, but the first tower (CUORE-0) is already taking data. The experimental techniques used will be presented as well as the preliminary CUORE-0 results. The current status of the full-mass experiment and its expected sensitivity will then be discussed.

Published
2016
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33. CUORE-0 detector: design, construction and operation

Author

N. Casali, R. Mazza, S. Zimmermann, C. Rosenfeld, G. Ventura, M. I. Martínez, P. Gorla, F. Ferroni, C. Tomei, Emanuele Ferri, Eugene E. Haller, G. Ceruti, A. Leder, Alan R. Smith, S. Copello, L. Ioannucci, Paolo Carniti, M. Iannone, David Miller, Massimiliano Nastasi, S. L. Wagaarachchi, R. Gaigher, M. Maino, H. W. Wang, C. Cosmelli, T. O'Donnell, Yu-Gang Ma, C. Nones, D. Conventi, A. Giuliani, S. Trentalange, Simone Capelli, R. W. Kadel, B. X. Zhu, Massimiliano Clemenza, S. Di Domizio, G. Fernandes, L. Tatananni, G. Piperno, Ettore Fiorini, R. Michinelli, Davide Chiesa, Claudio Gotti, C. Zarra, K. E. Lim, S. Zucchelli, N. Moggi, F. Orio, Vasundhara Singh, B. K. Fujikawa, James R. Wilson, N. Chott, Samuele Sangiorgio, Stefano Nisi, Stefano Pozzi, A. Nucciotti, C. J. Davis, Oliviero Cremonesi, G. Keppel, D. R. Artusa, Monica Sisti, C. Brofferio, C. Alduino, P. J. Mosteiro, K. Alfonso, F. Bragazzi, G. Erme, M. L. Di Vacri, T. I. Banks, G. Bari, B. S. Wang, Y. u. G. Kolomensky, D. Santone, Ioan Dafinei, L. Carbone, A. Bersani, Marco Pallavicini, O. Azzolini, Lindley Winslow, M. Vignati, M. Cariello, M. Balata, H. Z. Huang, L. Taffarello, G. Pessina, Stefano Dell'Oro, M. Pavan, L. Zanotti, E. V. Hansen, X. Liu, Luigi Cappelli, R. Pedrotta, Nicholas Scielzo, A. Caminata, J. Wallig, Ezio Previtali, Lorenzo Cassina, A. Pelosi, Jeremy S. Cushman, C. Bulfon, F. Stivanello, C. Rusconi, M. Faverzani, V. Pettinacci, R. Cereseto, L. Pattavina, L. Cardani, G. Pancaldi, D. Biare, M. Perego, L. Canonica, L. Marini, Kevin Hickerson, A. Buccheri, A. Giachero, M. Capodiferro, D. Q. Fang, V. Palmieri, Eric B. Norman, J. W. Beeman, S. Meijer, Silvio Morganti, M. Guetti, Guoqiang Zhang, M. Biassoni, J. L. Ouellet, Ke Han, Reina H. Maruyama, A. Drobizhev, Stuart J. Freedman, C. Pagliarone, D. Orlandi, T. Wise, A. Chiarini, S. Pirro, F. Terranova, Elena Sala, Y. Mei, M. Tessaro, L. Gladstone, R. Hennings-Yeomans, Xi-Guang Cao, R. J. Creswick, K. M. Heeger, M. M. Deninno, F. Bellini, M. Tenconi, C. Bucci, T. D. Gutierrez, L. DiPaolo, L. Gironi, F. T. Avignone, A. D'Addabbo, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPhP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, CUORE, Alduino, C, Alfonso, K, Artusa, D, Iii, F, Azzolini, O, Balata, M, Banks, T, Bari, G, Beeman, J, Bellini, F, Bersani, A, Biare, D, Biassoni, M, Bragazzi, F, Brofferio, C, Buccheri, A, Bucci, C, Bulfon, C, Caminata, A, Canonica, L, Cao, X, Capelli, S, Capodiferro, M, Cappelli, L, Carbone, L, Cardani, L, Cariello, M, Carniti, P, Casali, N, Cassina, L, Cereseto, R, Ceruti, G, Chiarini, A, Chiesa, D, Chott, N, Clemenza, M, Conventi, D, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D'Addabbo, A, Dafinei, I, Davis, C, Dell'Oro, S, Deninno, M, Domizio, S, Vacri, M, Dipaolo, L, Drobizhev, A, Erme, G, Fang, D, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Freedman, S, Fujikawa, B, Gaigher, R, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Guetti, M, Gutierrez, T, Haller, E, Han, K, Hansen, E, Heeger, K, Hennings Yeomans, R, Hickerson, K, Huang, H, Iannone, M, Ioannucci, L, Kadel, R, Keppel, G, Kolomensky, Y, Leder, A, Lim, K, Liu, X, Ma, Y, Maino, M, Marini, L, Martinez, M, Maruyama, R, Mazza, R, Mei, Y, Meijer, S, Michinelli, R, Miller, D, Moggi, N, Morganti, S, Mosteiro, P, Nastasi, M, Nisi, S, Nones, C, Norman, E, Nucciotti, A, O'Donnell, T, Orio, F, Orlandi, D, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pancaldi, G, Pattavina, L, Pavan, M, Pedrotta, R, Pelosi, A, Perego, M, Pessina, G, Pettinacci, V, Piperno, G, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sala, E, Sangiorgio, S, Santone, D, Scielzo, N, Singh, V, Sisti, M, Smith, A, Stivanello, F, Taffarello, L, Tatananni, L, Tenconi, M, Terranova, F, Tessaro, M, Tomei, C, Trentalange, S, Ventura, G, Vignati, M, Wagaarachchi, S, Wallig, J, Wang, B, Wang, H, Wilson, J, Winslow, L, Wise, T, Zanotti, L, Zarra, C, Zhang, G, Zhu, B, Zimmermann, S, Zucchelli, S, Cuore, Collaboration, Alduino, C., Alfonso, K., Artusa, D. R., Avignone III, F. T., Azzolini, O., Balata, M., Banks, T. I., Bari, G., Beeman, J. W., Bellini, F., Bersani, A., Biare, D., Biassoni, M., Bragazzi, F., Brofferio, C., Buccheri, A., Bucci, C., Bulfon, C., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Capodiferro, M., Cappelli, L., Carbone, L., Cardani, L., Cariello, M., Carniti, P., Casali, N., Cassina, L., Cereseto, R., Ceruti, G., Chiarini, A., Chiesa, D., Chott, N., Clemenza, M., Conventi, D., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Dipaolo, L., Drobizhev, A., Erme, G., Fang, D. Q., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Freedman, S. J., Fujikawa, B. K., Gaigher, R., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Guetti, M., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Iannone, M., Ioannucci, L., Kadel, R., Keppel, G., Kolomensky, Yu. G., Leder, A., Lim, K. E., Liu, X., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mazza, R., Mei, Y., Meijer, S., Michinelli, R., Miller, D., Moggi, N., Morganti, S., Mosteiro, P. J., Nastasi, M., Nisi, S., Nones, C., Norman, E. B., Nucciotti, A., O'Donnell, T., Orio, F., Orlandi, D., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pancaldi, G., Pattavina, L., Pavan, M., Pedrotta, R., Pelosi, A., Perego, M., Pessina, G., Pettinacci, V., Piperno, G., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sala, E., Sangiorgio, S., Santone, D., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Stivanello, F., Taffarello, L., Tatananni, L., Tenconi, M., Terranova, F., Tessaro, M., Tomei, C., Trentalange, S., Ventura, G., Vignati, M., Wagaarachchi, S. L., Wallig, J., Wang, B. S., Wang, H. W., Wilson, J., Winslow, L. A., Wise, T., Zanotti, L., Zarra, C., Zhang, G. Q., Zhu, B. X., Zimmermann, S., and Zucchelli, S.

Subjects
J.2, Physics - Instrumentation and Detectors, Cryogenics, Cryogenic, FOS: Physical sciences, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], CUORE Experiment, 01 natural sciences, tellurium: oxygen, Calorimeters, Double-beta decay detectors, Instrumentation, Mathematical Physics, CUORE, bolometer, 0103 physical sciences, Neutrino Physics, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Double Beta Decay (0 Neutrino), Nuclear Experiment (nucl-ex), 010306 general physics, Nuclear Experiment, detector: design, Physics, Cryogenic Engineering, Calorimeter, 010308 nuclear & particles physics, Instrumentation and Detectors (physics.ins-det), Bolometers, Cryostat, Double-beta decay detector, tellurium: nuclide, Physics - Instrumentation and Detector, Bolometers, Cryogenic Engineering, Double Beta Decay (0 Neutrino), CUORE Experiment, Neutrino Physics, Cryostat, Humanities, Tellurium compounds
Abstract

The CUORE experiment will search for neutrinoless double-beta decay of $^{130}$Te with an array of 988 TeO$_2$ bolometers arranged in 19 towers. CUORE-0, the first tower assembled according to the CUORE procedures, was built and commissioned at Laboratori Nazionali del Gran Sasso, and took data from March 2013 to March 2015. In this paper we describe the design, construction and operation of the CUORE-0 experiment, with an emphasis on the improvements made over a predecessor experiment, Cuoricino. In particular, we demonstrate with CUORE-0 data that the design goals of CUORE are within reach., Comment: 39 pages, 26 figures

Published
2016
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34. Status of the CUORE and results from the CUORE-0 neutrinoless double beta decay experiments

Author

M. M. Deninno, S. Di Domizio, C. Zarra, Lucia Canonica, B. K. Fujikawa, Stefano Pozzi, Stefano Dell'Oro, F. Bellini, X. Liu, Massimiliano Nastasi, L. Gironi, F. T. Avignone, A. Giuliani, T. I. Banks, N. Casali, S. Pirro, M. Vignati, A. Bersani, F. Orio, Massimiliano Clemenza, Carlo Cosmelli, C. Rosenfeld, M. Balata, G. Bari, Vladimir Datskov, L. Pattavina, G. Ventura, S. Trentalange, S. Copello, N. Moggi, C. Nones, Yu-Gang Ma, B. S. Wang, R. J. Creswick, P. Gorla, Samuele Sangiorgio, Stefano Nisi, O. Azzolini, Y. L. Li, Oliviero Cremonesi, Marisa Pedretti, A. Nucciotti, C. Brofferio, H. Z. Huang, F. Ferroni, C. Tomei, M. Tenconi, Emanuele Ferri, Ettore Fiorini, H. A. Farach, Andrea Giachero, M. Faverzani, Eugene E. Haller, G. Fernandes, L. Taffarello, Marco Pallavicini, Jeremy S. Cushman, W. D. Tian, Alan R. Smith, N. Chott, G. Pessina, M. L. Di Vacri, Davide Chiesa, K. E. Lim, Nicholas Scielzo, A. Camacho, S. Zucchelli, L. Carbone, C. Bucci, T. D. Gutierrez, Guimin Zhang, Jeffrey W. Beeman, John Wilson, A. Dally, Claudio Gotti, M. Maino, C. Pira, Yu. G. Kolomensky, Luigi Cappelli, Simone Capelli, H. W. Wang, R. W. Kadel, G. Keppel, D. R. Artusa, Larissa M. Ejzak, B. X. Zhu, T. O'Donnell, Monica Sisti, Lorenzo Cassina, V. Pettinacci, L. Cardani, C. Maiano, Lindley Winslow, X. Z. Cai, L. Wielgus, Carlo Ligi, C. Rusconi, G. Piperno, S. Morganti, M. I. Martínez, Ioan Dafinei, L. Zanotti, M. Pavan, A. Drobizhev, D. Orlandi, Kevin Hickerson, M. A. Franceschi, D. Q. Fang, C. Pagliarone, T. Wise, V. Palmieri, A. Caminata, Elena Sala, Ezio Previtali, Y. Mei, Eric B. Norman, T. Napolitano, R. Hennings-Yeomans, Xi-Guang Cao, K. M. Heeger, M. Biassoni, Ke Han, Reina H. Maruyama, Stuart J. Freedman, J. L. Ouellet, A. Woodcraft, F. Terranova, Sisti, M, Artusa, D, Avignone, F, Azzolini, O, Balata, M, Banks, T, Bari, G, Beeman, J, Bellini, F, Bersani, A, Biassoni, M, Brofferio, C, Bucci, C, Cai, X, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, Dafinei, I, Dally, A, Datskov, V, Dell'Oro, S, Deninno, M, Di Domizio, S, di Vacri, M, Drobizhev, A, Ejzak, L, Fang, D, Farach, H, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Haller, E, Han, K, Heeger, K, Hennings Yeomans, R, Hickerson, K, Huang, H, Kadel, R, Keppel, G, Kolomensky, Y, Li, Y, Ligi, C, Lim, K, Liu, X, Ma, Y, Maiano, C, Maino, M, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nisi, S, Nones, C, Norman, E, Nucciotti, A, O'Donnell, T, Orio, F, Orlandi, D, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pedretti, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sala, E, Sangiorgio, S, Scielzo, N, Smith, A, Taffarello, L, Tenconi, M, Terranova, F, Tian, W, Tomei, C, Trentalange, S, Ventura, G, Vignati, M, Wang, B, Wang, H, Wielgus, L, Wilson, J, Winslow, L, Wise, T, Woodcraft, A, Zanotti, L, Zarra, C, Zhang, G, Zhu, B, Zucchelli, S, Sisti, M., Artusa, D.R., Avignone, F.T., Azzolini, O., Balata, M., Banks, T.I., Bari, G., Beeman, J., Bellini, F., Bersani, A., Biassoni, M., Brofferio, C., Bucci, C., Cai, X.Z., Camacho, A., Caminata, A., Canonica, L., Cao, X.G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R.J., Cushman, J.S., Dafinei, I., Dally, A., Datskov, V., Dell'Oro, S., Deninno, M.M., Di Domizio, S., di Vacri, M.L., Drobizhev, A., Ejzak, L., Fang, D.Q., Farach, H.A., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M.A., Freedman, S.J., Fujikawa, B.K., Giachero, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T.D., Haller, E.E., Han, K., Heeger, K.M., Hennings-Yeomans, R., Hickerson, K.P., Huang, H.Z., Kadel, R., Keppel, G., Kolomensky, Yu.G., Li, Y.L., Ligi, C., Lim, K.E., Liu, X., Ma, Y.G., Maiano, C., Maino, M., Martinez, M., Maruyama, R.H., Mei, Y., Moggi, N., Morganti, S., Napolitano, T., Nastasi, M., Nisi, S., Nones, C., Norman, E.B., Nucciotti, A., O'Donnell, T., Orio, F., Orlandi, D., Ouellet, J.L., Pagliarone, C.E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pedretti, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, Stefano, Previtali, E., Rosenfeld, C., Rusconi, C., Sala, E., Sangiorgio, S., Scielzo, N.D., Smith, A.R., Taffarello, L., Tenconi, M., Terranova, F., Tian, W.D., Tomei, C., Trentalange, S., Ventura, G., Vignati, M., Wang, B.S., Wang, H.W., Wielgus, L., Wilson, J., Winslow, L.A., Wise, T., Woodcraft, A., Zanotti, L., Zarra, C., Zhang, G.Q., Zhu, B.X., and Zucchelli, S.

Subjects
Physics, Particle physics, Nuclear and High Energy Physics, 010308 nuclear & particles physics, Bolometer, Bolometers, 01 natural sciences, Beta decay, Double beta decay, Particle detector, Massless particle, Nuclear physics, CUORE, Neutrino mass, 0103 physical sciences, Neutrino, 010306 general physics, Neutrino ma, Radioactive decay, Lepton
Abstract

CUORE is a 741kg array of TeO 2 bolometers for the search of neutrinoless double beta decay of 130 Te. The detectoris being constructed at the Laboratori Nazionali del Gran Sasso, Italy, where it will start taking data in 2015. If thetarget background of 0.01counts/(keVkgy) will be reached, in five years of data taking CUORE will have a 1˙halflife sensitivity of 10 26 y. CUORE-0 is a smaller experiment constructed to test and demonstrate the performancesexpected for CUORE. The detector is a single tower of 52 CUORE-like bolometers that started taking data in spring2013. The status and perspectives of CUORE will be discussed, and the first CUORE-0 data will be presented.Keywords: Double beta decay, Neutrino mass, Bolometers1. IntroductionNeutrinos are massive particles. A beautiful proof ofthis important property was obtained by neutrino oscil-lation experiments more than a decade ago. Since then,the key role of neutrinoless double beta decay searcheshas been established, as attested by the growing numberof experimental proposals in the last years.Neutrinoless double beta decay ( 0 ) is a proposedvery rare nuclear process in which a nucleus transformsinto its (A,Z+2) isobar with the emission of two elec-trons. While the two neutrino channel ( 2 ) – wheretwo neutrinos are contemporary emitted in the decay – isallowed by the Standard Model of Particle Physics andhas been observed experimentally in a dozen of isotopeswith half-lives of the order 10

Published
2016

35. Search for Neutrinoless Double-Beta Decay ofTe130with CUORE-0

Author

Kevin Hickerson, A. Bersani, G. Piperno, L. Carbone, C. Pagliarone, Oliviero Cremonesi, A. Caminata, Ettore Fiorini, Alan R. Smith, L. Pattavina, Andrea Giachero, C. Bucci, T. D. Gutierrez, C. Rosenfeld, P. Gorla, A. Giuliani, H. Z. Huang, Larissa M. Ejzak, James R. Wilson, Nicholas Scielzo, T. Wise, F. Ferroni, C. Tomei, Emanuele Ferri, S. Di Domizio, G. Keppel, A. Drobizhev, N. Casali, K. Alfonso, Davide Chiesa, N. Moggi, M. L. Di Vacri, Eugene E. Haller, K. E. Lim, C. Rusconi, T. I. Banks, M. I. Martínez, D. R. Artusa, D. Orlandi, V. Pettinacci, L. Taffarello, Samuele Sangiorgio, Stefano Nisi, C. Zarra, M. Tenconi, Monica Sisti, A. Nucciotti, S. Copello, Jeffrey W. Beeman, B. K. Fujikawa, Stefano Pozzi, M. Faverzani, B. X. Zhu, S. L. Wagaarachchi, A. Dally, Lorenzo Cassina, Yu-Gang Ma, G. Ventura, V. Palmieri, Ezio Previtali, L. Gironi, Claudio Gotti, F. T. Avignone, G. Bari, Stefano Dell'Oro, M. Vignati, Eric B. Norman, X. Liu, N. Chott, Yu G. Kolomensky, Silvio Morganti, D. Q. Fang, F. Terranova, Marco Pallavicini, M. Maino, Lindley Winslow, D. Santone, Ioan Dafinei, H. W. Wang, T. O'Donnell, M. Pavan, Luigi Cappelli, G. Fernandes, S. Pirro, Elena Sala, S. Trentalange, E. V. Hansen, L. Wielgus, Y. Mei, L. Zanotti, G. Pessina, Simone Capelli, R. W. Kadel, J. L. Ouellet, Xi-Guang Cao, K. M. Heeger, R. Hennings-Yeomans, Guoqiang Zhang, S. Zucchelli, Ke Han, Reina H. Maruyama, C. Nones, Massimiliano Clemenza, Carlo Cosmelli, F. Orio, C. Brofferio, B. S. Wang, O. Azzolini, L. Cardani, Jeremy S. Cushman, Stuart Freedman, R. J. Creswick, M. Balata, M. M. Deninno, M. Biassoni, Lucia Canonica, F. Bellini, and Marisa Pedretti

Subjects
Physics, Nuclear physics, MAJORANA, CUORE, Double beta decay, General Physics and Astronomy, Beta (velocity), Detector array, Neutrino, Upper and lower bounds, Background level
Abstract

We report the results of a search for neutrinoless double-beta decay in a 9.8 kg yr exposure of Te-130 using a bolometric detector array, CUORE-0. The characteristic detector energy resolution and background level in the region of interest are 5.1 +/- 0.3 keV FWHM and 0.058 +/- 0.004(stat) +/- 0.002(syst)counts/(keV kg yr), respectively. The median 90% C.L. lower-limit half-life sensitivity of the experiment is 2.9 x 10(24) yr and surpasses the sensitivity of previous searches. We find no evidence for neutrinoless double-beta decay of Te-130 and place a Bayesian lower bound on the decay half-life, T-1/2(0 nu) > 2.7 x 10(24) yr at 90% C.L. Combining CUORE-0 data with the 19.75 kg yr exposure of Te-130 from the Cuoricino experiment we obtain T-1/2(0 nu) > 4.0 x 10(24) yr at 90% C.L. (Bayesian), the most stringent limit to date on this half-life. Using a range of nuclear matrix element estimates we interpret this as a limit on the effective Majorana neutrino mass, m beta beta < 270-760 meV.

Published
2015
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37. MDRO Beijing Consensus Meeting Report: Global burden of multidrug-resistant organisms’ current antimicrobial resistance problems in Asia-Pacific

Author

Gui-Qiang Wang, John D. Turnidge, Ian M. Gould, Jim Hutchinson, Timothy R. Walsh, V. K. E. Lim, and Jiunn-Jong Wu

Subjects
Microbiology (medical), business.industry, education, Immunology, Microbiology, Beijing Consensus, Biotechnology, Multiple drug resistance, Antibiotic resistance, Asia pacific, Environmental health, Immunology and Allergy, Antibiotic Stewardship, Medicine, business
Abstract

The International Society of Chemotherapy's Working Groups on Antibiotic Resistance and Antibiotic Stewardship convened a half-day workshop on the burden of multidrug-resistant organisms in the Asia-Pacific. This short review is a summary of their discussion and conclusions.

Published
2014
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38. Limits on spin-dependent WIMP-nucleon cross sections from 225 live days of XENON100 data

Author

Marc Schumann, P. Shagin, A. Behrens, Ehud Duchovni, E. Pantic, M. Messina, J. A. M. Lopes, A. Kish, M. Garbini, K. Arisaka, Jean-Pierre Cussonneau, Hardy Simgen, A. D. Ferella, D. Thers, Boris Bauermeister, R. F. Lang, João Cardoso, K. Lung, A. P. Colijn, T. Marrodán Undagoitia, Ch. Weinheimer, Laura Baudis, Hui Wang, F. Gao, M. P. Decowski, Manfred Lindner, C. Ghag, C. Levy, M. Selvi, W. T. Chen, J. Lamblin, H. Landsman, Daniel Lellouch, P. R. Scovell, H. Contreras, P. Beltrame, Florian Kaether, Kaixuan Ni, Ran Budnik, F. V. Massoli, A. Molinario, Qing Lin, B. Choi, J.M.F. dos Santos, L. Scotto Lavina, Sebastian Lindemann, S. Rosendahl, S. Fattori, A. Teymourian, N. Priel, C. Balan, W. Hampel, Karl Giboni, W. Fulgione, Ethan Brown, Elena Aprile, F. Arneodo, April S. Brown, Uwe Oberlack, K. E. Lim, Jochen Schreiner, C. Grignon, A. J. Melgarejo Fernandez, M. Le Calloch, M. Alfonsi, O. Vitells, A. Rizzo, S. E. A. Orrigo, Y. Meng, Giacomo Bruno, G. Sartorelli, M. Weber, G. Plante, Luke Goetzke, K. Bokeloh, E. K. U. Gross, R. Persiani, Astroparticle Physics (IHEF, IoP, FNWI), Laboratoire SUBATECH Nantes (SUBATECH), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Nantes (UN)-Mines Nantes (Mines Nantes), XENON100, E. Aprile, M. Alfonsi, K. Arisaka, F. Arneodo, C. Balan, L. Baudi, B. Bauermeister, A. Behren, P. Beltrame, K. Bokeloh, A. Brown, E. Brown, G. Bruno, R. Budnik, J. M. R. Cardoso, W.-T. Chen, B. Choi, A. P. Colijn, H. Contrera, J. P. Cussonneau, M. P. Decowski, E. Duchovni, S. Fattori, A. D. Ferella, W. Fulgione, F. Gao, M. Garbini, C. Ghag, K.-L. Giboni, L. W. Goetzke, C. Grignon, E. Gro, W. Hampel, F. Kaether, A. Kish, J. Lamblin, H. Landsman, R. F. Lang, M. Le Calloch, D. Lellouch, C. Levy, K. E. Lim, Q. Lin, S. Lindemann, M. Lindner, J. A. M. Lope, K. Lung, T. Marrodán Undagoitia, F. V. Massoli, A. J. Melgarejo Fernandez, Y. Meng, M. Messina, A. Molinario, K. Ni, U. Oberlack, S. E. A. Orrigo, E. Pantic, R. Persiani, G. Plante, N. Priel, A. Rizzo, S. Rosendahl, J. M. F. dos Santo, G. Sartorelli, J. Schreiner, M. Schumann, L. Scotto Lavina, P. R. Scovell, M. Selvi, P. Shagin, H. Simgen, A. Teymourian, D. Ther, O. Vitell, H. Wang, M. Weber, C. Weinheimer, and XENON100 collaboration

Subjects
Cosmology and Nongalactic Astrophysics (astro-ph.CO), [PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], Dark matter, General Physics and Astronomy, FOS: Physical sciences, 01 natural sciences, dark matter, Particle detector, High Energy Physics - Experiment, Nuclear physics, Cross section (physics), High Energy Physics - Experiment (hep-ex), High Energy Physics - Phenomenology (hep-ph), WIMP, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], 010306 general physics, Pseudovector, Instrumentation and Methods for Astrophysics (astro-ph.IM), Spin-½, Physics, 010308 nuclear & particles physics, [SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], High Energy Physics - Phenomenology, [PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph], Astrophysics - Instrumentation and Methods for Astrophysics, Nucleon, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We present new experimental constraints on the elastic, spin-dependent WIMP-nucleon cross section using recent data from the XENON100 experiment, operated in the Laboratori Nazionali del Gran Sasso in Italy. An analysis of 224.6 live days x 34 kg of exposure acquired during 2011 and 2012 revealed no excess signal due to axial-vector WIMP interactions with 129-Xe and 131-Xe nuclei. This leads to the most stringent upper limits on WIMP-neutron cross sections for WIMP masses above 6 GeV, with a minimum cross section of 3.5 x 10^{-40} cm^2 at a WIMP mass of 45 GeV, at 90% confidence level., Comment: 5 pages, 3 figures; corrected caption of figure 3

Published
2013
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39. Clinical guidelines for the management of cancer patients with neutropenia and unexplained fever

Author

A. Harryanto Reksodiputro, Shaeng Fung Lin, Cheng-Yi Liu, Dody Ranuhardy, Kazuo Tamura, Tetsuro Matsumoto, Saengsuree Jootar, Juan J. Picazo, Yung Ching Liu, V. K. E. Lim, Wang Chun, Altaf Ahmed, Panpit Suwangool, Adrian Ong, S. Visalachy Purushotaman, Shen Zhixiang, Dong-Gun Lee, Po-Ren Hsueh, Huang Xiao Jun, Manolito Chua, and Yasser Hussain

Subjects
Microbiology (medical), medicine.medical_specialty, Neutropenia, Guidelines as Topic, beta-Lactams, Fever of Unknown Origin, beta-Lactamases, Risk Factors, Neoplasms, Epidemiology, medicine, Humans, Pharmacology (medical), Fever of unknown origin, Risk factor, Intensive care medicine, Leukopenia, business.industry, Cancer, Bacterial Infections, General Medicine, medicine.disease, Antimicrobial, Anti-Bacterial Agents, Treatment Outcome, Infectious Diseases, Etiology, Drug Therapy, Combination, medicine.symptom, beta-Lactamase Inhibitors, business
Abstract

Neutropenia is a frequent complication in patients with malignancies undergoing cytostatic chemotherapy. It is also an important risk factor for infection. Fever is often the only sign of infection in neutropenic cancer patients. Although infections cannot be documented in a large proportion of febrile neutropenic cancer patients, empirical antimicrobial therapy based on clinical evidence and local data on microbiological epidemiology and susceptibility must be started immediately. The following recommendations for antimicrobial use in neutropenic patients with fever of unknown origin have been issued by a group of experts from countries belonging to the Asia–Pacific region. The task has been particularly challenging because of the significant differences among the participating countries, mainly in terms of microbiological epidemiology and resistance patterns. Indeed, in most countries of the region, and in contrast to the Western world, Gram-negative bacteria are the prevailing etiological agent of infections in febrile granulocytopenic patients. An additional difficulty has been the varying microbial susceptibility profiles and the high prevalence of methicillin-resistant Staphylococcus aureus (MRSA), coagulase-negative staphylococci, vancomycin-resistant enterococci, viridans group streptococci, ciprofloxacin-resistant Escherichia coli and Pseudomonas aeruginosa, among others. The recommendations that follow should be expected to provide general guidance to clinicians who care for febrile neutropenic cancer patients, rather than to operate as a substitute for their clinical judgment. 2. Definitions

Published
2005
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40. The distributed Slow Control System of the XENON100 experiment

Author

Y. Mei, E. Pantic, Jean-Pierre Cussonneau, F. V. Massoli, Qing Lin, A. Manzur, K. E. Lim, O. Vitells, A. C. C. Ribeiro, Giacomo Bruno, W. Fulgione, A. Rizzo, B. Choi, J. A. M. Lopes, L. Scotto Lavina, A. Kish, Ethan Brown, Gabriella Sartorelli, E. Duchovni, Laura Baudis, W. Hampel, A. D. Ferella, M. Weber, S. E. A. Orrigo, João Cardoso, M. Selvi, F. Gao, G. Plante, T. Marrodán Undagoitia, Kaixuan Ni, Ch. Weinheimer, P. Beltrame, R. Persiani, Hui Wang, W. T. Chen, S. Rosendahl, Marc Schumann, P. Shagin, A. Molinario, A. Teymourian, K. Arisaka, H. Simgen, Uwe Oberlack, P. R. Scovell, S. Fattori, Daniel McKinsey, H. Contreras, F. Arneodo, M. Garbini, Eilam Gross, Luke Goetzke, A. Behrens, K. Bokeloh, Y. Meng, Elena Aprile, E. Nativ, Ran Budnik, A. J. Melgarejo Fernandez, K. Lung, C. Levy, M. Alfonsi, J.M.F. dos Santos, R. F. Lang, M. Le Calloch, Stefan Lindemann, J. Lamblin, J. Schreiner, M. P. Decowski, Manfred Lindner, C. Balan, N. Priel, D. Thers, C. Grignon, K. L. Giboni, J. V. Patricio, E Aprile, M Alfonsi, K Arisaka, F Arneodo, C Balan, L Baudi, A Behren, P Beltrame, K Bokeloh, E Brown, G M Bruno, R Budnik, M Le Calloch, J M Cardoso, W -T Chen, B Choi, H Contrera, J -P Cussonneau, M P Decowski, E Duchovni, S Fattori, A D Ferella, W Fulgione, F Gao, M Garbini, K -L Giboni, L W Goetzke, C Grignon, E Gro, W Hampel, D N McKinsey, A Kish, J Lamblin, R F Lang, C Levy, K E Lim, Q Lin, S Lindemann, M Lindner, J A M Lope, K Lung, A Manzur, T Marrodán Undagoitia, F V Massoli, Y Mei, A J Melgarejo Fernandez, Y Meng, A Molinario, E Nativ, K Ni, U Oberlack, S E A Orrigo, E Pantic, J V Patricio, R Persiani, G Plante, N Priel, A C C Ribeiro, A Rizzo, S Rosendahl, J M F dos Santo, G Sartorelli, J Schreiner, M Schumann, L Scotto Lavina, P R Scovell, M Selvi, P Shagin, H Simgen, A Teymourian, D Ther, O Vitell, H Wang, M Weber, C Weinheimer, Laboratoire SUBATECH Nantes (SUBATECH), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Nantes (UN)-Mines Nantes (Mines Nantes), XENON100, IoP (FNWI), Gravitation and Astroparticle Physics Amsterdam, GRAPPA (ITFA, IoP, FNWI), Faculty of Science, and Other Research IHEF (IoP, FNWI)

Subjects
Physics - Instrumentation and Detectors, architecture, [PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], Java, Computer science, Real-time computing, FOS: Physical sciences, chemistry.chemical_element, Control and monitor systems online, Control systems, Detector control systems (detector and experiment monitoring and slow-control systems, architecture, hardware, algorithms, databases), algorithms, 01 natural sciences, Xenon, 0103 physical sciences, hardware, DETECTOR CONTROL SYSTEMS, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], CONTROL SYSTEMS, 010306 general physics, Instrumentation and Methods for Astrophysics (astro-ph.IM), Instrumentation, Mathematical Physics, computer.programming_language, Time projection chamber, 010308 nuclear & particles physics, business.industry, Detector control systems (detector and experiment monitoring and slow-control systems, Emphasis (telecommunications), Volume (computing), Instrumentation and Detectors (physics.ins-det), Modular design, [SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], chemistry, Control system, Astrophysics - Instrumentation and Methods for Astrophysics, databases), business, computer, System software
Abstract

The XENON100 experiment, in operation at the Laboratori Nazionali del Gran Sasso (LNGS) in Italy, was designed to search for evidence of dark matter interactions inside a volume of liquid xenon using a dual-phase time projection chamber. This paper describes the Slow Control System (SCS) of the experiment with emphasis on the distributed architecture as well as on its modular and expandable nature. The system software was designed according to the rules of Object-Oriented Programming and coded in Java, thus promoting code reusability and maximum flexibility during commissioning of the experiment. The SCS has been continuously monitoring the XENON100 detector since mid 2008, remotely recording hundreds of parameters on a few dozen instruments in real time, and setting emergency alarms for the most important variables., Comment: 12 pages, 4 figures

Published
2012
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41. Dark Matter Results from 100 Live Days of XENON100 Data

Author

K. Arisaka, Marc Schumann, P. Shagin, F. Arneodo, J. A. M. Lopes, A. Kish, G. Sartorelli, K. E. Lim, R. Santorelli, Manfred Lindner, C. W. Lam, K. Bokeloh, S. Fattori, A. Behrens, M. Selvi, J. Lamblin, Eilam Gross, Elena Aprile, David B. Cline, D. Thers, Y. Mei, E. Pantic, R. F. Lang, A. Teymourian, R. Persiani, Ethan Brown, T. Bruch, K. L. Giboni, Hardy Simgen, A. D. Ferella, Hongwei Wang, M. Weber, T. Marrodán Undagoitia, C. Levy, Ch. Weinheimer, B. Choi, G. Plante, K. Lung, Laura Baudis, J.M.F. dos Santos, Sebastian Lindemann, Kaixuan Ni, A. J. Melgarejo Fernandez, S. E. A. Orrigo, A. C. C. Ribeiro, Giacomo Bruno, O. Vitells, Uwe Oberlack, Qing Lin, Ehud Duchovni, A. Askin, João Cardoso, F. Gao, W. T. Chen, E. Aprile, K. Arisaka, F. Arneodo, A. Askin, L. Baudi, A. Behren, K. Bokeloh, E. Brown, T. Bruch, G. Bruno, J. M. R. Cardoso, W.-T. Chen, B. Choi, D. Cline, E. Duchovni, S. Fattori, A. D. Ferella, F. Gao, K.-L. Giboni, E. Gro, A. Kish, C. W. Lam, J. Lamblin, R. F. Lang, C. Levy, K. E. Lim, Q. Lin, S. Lindemann, M. Lindner, J. A. M. Lope, K. Lung, T. Marrodan Undagoitia, Y. Mei, A. J. Melgarejo Fernandez, K. Ni| U. Oberlack, S. E. A. Orrigo, E. Pantic, R. Persiani, G. Plante, A. C. C. Ribeiro, R. Santorelli, J. M. F. dos Santo, G. Sartorelli, M. Schumann, M. Selvi, P. Shagin, H. Simgen, A. Teymourian, D. Ther, O. Vitell, H. Wang, M. Weber, C. Weinheimer, Laboratoire SUBATECH Nantes (SUBATECH), Mines Nantes (Mines Nantes)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), and XENON100

Subjects
Physics, Cosmology and Nongalactic Astrophysics (astro-ph.CO), Large Underground Xenon experiment, 010308 nuclear & particles physics, DARK MATTER, Dark matter, Hadron, FOS: Physical sciences, General Physics and Astronomy, Elementary particle, Fermion, 01 natural sciences, Particle detector, High Energy Physics - Experiment, WIMPS, Nuclear physics, High Energy Physics - Experiment (hep-ex), XENON, WIMP, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], TPC, 010306 general physics, Nucleon, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We present results from the direct search for dark matter with the XENON100 detector, installed underground at the Laboratori Nazionali del Gran Sasso of INFN, Italy. XENON100 is a two-phase time projection chamber with a 62 kg liquid xenon target. Interaction vertex reconstruction in three dimensions with millimeter precision allows to select only the innermost 48 kg as ultra-low background fiducial target. In 100.9 live days of data, acquired between January and June 2010, no evidence for dark matter is found. Three candidate events were observed in a pre-defined signal region with an expected background of 1.8 +/- 0.6 events. This leads to the most stringent limit on dark matter interactions today, excluding spin-independent elastic WIMP-nucleon scattering cross-sections above 7.0x10^-45 cm^2 for a WIMP mass of 50 GeV/c^2 at 90% confidence level., 5 pages, 5 figures; matches accepted version

Published
2011
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42. Implications on inelastic dark matter from 100 live days of XENON100 data

Author

E. Pantic, Ethan Brown, M. Selvi, David B. Cline, Y. Mei, J.M.F. dos Santos, Hui Wang, T. Marrodán Undagoitia, Manfred Lindner, Ch. Weinheimer, B. Choi, A. Behrens, Sebastian Lindemann, Karl Giboni, K. Arisaka, R. Santorelli, F. Arneodo, M. Weber, G. Plante, Hardy Simgen, A. D. Ferella, S. Fattori, J. A. M. Lopes, K. Lung, A. Kish, Laura Baudis, A. Teymourian, C. W. Lam, D. Thers, R. F. Lang, A. C. C. Ribeiro, Giacomo Bruno, Elena Aprile, C. Levy, T. Bruch, Kaixuan Ni, K. E. Lim, S. E. A. Orrigo, J. Lamblin, Uwe Oberlack, O. Vitells, Ehud Duchovni, A. J. Melgarejo Fernandez, Qing Lin, A. Askin, João Cardoso, F. Gao, W. T. Chen, Marc Schumann, P. Shagin, G. Sartorelli, R. Persiani, K. Bokeloh, E. K. U. Gross, E. Aprile, K. Arisaka, F. Arneodo, A. Askin, L. Baudi, A. Behren, K. Bokeloh, E. Brown, T. Bruch, G. Bruno, J. M. R. Cardoso, W.-T. Chen, B. Choi, D. Cline, E. Duchovni, S. Fattori, A. D. Ferella, F. Gao, K.-L. Giboni, E. Gro, A. Kish, C. W. Lam, J. Lamblin, R. F. Lang, C. Levy, K. E. Lim, Q. Lin, S. Lindemann, M. Lindner, J. A. M. Lope, K. Lung, T. Marrodán Undagoitia, Y. Mei, A. J. Melgarejo Fernandez, K. Ni, U. Oberlack, S. E. A. Orrigo, E. Pantic, R. Persiani, G. Plante, A. C. C. Ribeiro, R. Santorelli, J. M. F. dos Santo, G Sartorelli, M. Schumann, M. Selvi, P. Shagin, H. Simgen, A. Teymourian, D. Ther, O. Vitell, H. Wang, M. Weber, C. Weinheimer, Laboratoire SUBATECH Nantes (SUBATECH), Mines Nantes (Mines Nantes)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), and XENON100

Subjects
Physics, Nuclear and High Energy Physics, Cosmology and Nongalactic Astrophysics (astro-ph.CO), 010308 nuclear & particles physics, Scattering, DARK MATTER, Signal region, Dark matter, FOS: Physical sciences, 01 natural sciences, WIMPS, Nuclear physics, XENON, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], TPC, 010306 general physics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The XENON100 experiment has recently completed a dark matter run with 100.9 live-days of data, taken from January to June 2010. Events in a 48kg fiducial volume in the energy range between 8.4 and 44.6 keVnr have been analyzed. A total of three events have been found in the predefined signal region, compatible with the background prediction of (1.8 \pm 0.6) events. Based on this analysis we present limits on the WIMP-nucleon cross section for inelastic dark matter. With the present data we are able to rule out the explanation for the observed DAMA/LIBRA modulation as being due to inelastic dark matter scattering off iodine at a 90% confidence level., Comment: 3 pages, 3 figures

Published
2011
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43. DNA fingerprinting of human isolates of Salmonella enterica serotype Paratyphi B in Malaysia

Author

V. K. E. Lim, Savithri D. Puthucheary, Rohani Md Yasin, Y.T. Koh, Kwai Lin Thong, Z. Taib, and Yee-Ling Goh

Subjects
DNA, Bacterial, Male, clone (Java method), Serotype, Microbial Sensitivity Tests, Applied Microbiology and Biotechnology, Microbiology, Drug Resistance, Bacterial, Paratyphoid Fever, medicine, Pulsed-field gel electrophoresis, Cluster Analysis, Humans, Child, Aged, Molecular epidemiology, biology, Paratyphoid fever, Malaysia, UPGMA, Infant, General Medicine, medicine.disease, biology.organism_classification, DNA Fingerprinting, Electrophoresis, Gel, Pulsed-Field, DNA profiling, Salmonella paratyphi B, Salmonella enterica, Child, Preschool, Biotechnology
Abstract

Y . L . G O H , R . Y A S I N , S . D . P U T H U C H E A R Y , Y . T . K O H , V . K . E . L I M , Z . T A I B A N D K . L . T H O N G . 2003. Aims: DNA fingerprinting of Salmonella enterica serotype Paratyphi B isolated in Malaysia during 1982‐83, 1992 and 1996‐2002 was carried out by pulsed-field gel electrophoresis (PFGE), antimicrobial susceptibility tests and D-tartrate utilization tests to assess the extent of genetic diversity of these isolates in Malaysia. Methods and Results: Eighty-six human isolates and one food isolate of Salm. Paratyphi B were analysed by PFGE, antimicrobial susceptibility tests and D-tartrate utilization tests. Sixty-five strains were d-tartratenegative (dT)) while 22 strains were D-tartrate-positive (dT+). Thirty-seven per cent of the Salm. Paratyphi B strains were resistant to one or more antimicrobial agents. PFGE analysis clearly distinguished the dT) and dT+ strains into two clusters based on the unweighted pair group average method (UPGMA). Twenty-two XbaI-pulsotypes were observed among the 65 dT) strains while 17 XbaI-pulsotypes were observed among the 22 isolates of Salm. Paratyphi B dT+. Conclusions: The present study showed that PFGE was very discriminative with 33AE7% of the strains yielding distinct fingerprints. Paratyphoid fever in Malaysia is probably caused by one predominant, endemic clone of Salm. Paratyphi B dT) with various subtypes. There was no association between the pulsotypes and the severity of the disease indicating that the severity of the disease is probably multifactorial. Significance and Impact of the Study: The findings of the present study verify the usefulness of PFGE in characterizing strains of Salm. Paratyphi B. This is the first report on the application of PFGE on a large collection of Salm. Paratyphi B in Malaysia.

Published
2003
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44. CUORE-0 results and prospects for the CUORE experiment

Author

L. Carbone, C. Pagliarone, T. Wise, D. Q. Fang, N. Casali, A. Drobizhev, D. Orlandi, M. A. Franceschi, Massimiliano Clemenza, N. D. Scielzo, Carlo Cosmelli, M. I. Martínez, C. Bucci, B. X. Zhu, M. Faverzani, C. Maiano, T. D. Gutierrez, Davide Chiesa, R. J. Creswick, A. Dally, M. Maino, A. Woodcraft, F. Orio, L. Pattavina, K. E. Lim, Lorenzo Cassina, Claudio Gotti, G. Bari, H. W. Wang, L. Zanotti, Jeffrey W. Beeman, T. O'Donnell, T. I. Banks, C. Brofferio, M. M. Deninno, Oliviero Cremonesi, V. Palmieri, N. Chott, L. Taffarello, M. Pavan, B. S. Wang, M. Balata, Eric B. Norman, E. Previtali, A. Bersani, C. Rosenfeld, T. Napolitano, Lucia Canonica, V. Pettinacci, Guimin Zhang, James R. Wilson, O. Azzolini, P. Gorla, F. Bellini, F. Ferroni, N. Moggi, S. Di Domizio, Y. L. Li, C. Pira, L. Cardani, C. Tomei, A. Caminata, Emanuele Ferri, F. Terranova, Eugene E. Haller, Kevin Hickerson, H. Z. Huang, M. Tenconi, M. Biassoni, C. Nones, Samuele Sangiorgio, Stefano Nisi, C. Zarra, A. Nucciotti, B. K. Fujikawa, Stefano Pozzi, J. L. Ouellet, G. Keppel, D. R. Artusa, A. Camacho, Larissa M. Ejzak, L. Wielgus, Monica Sisti, Marisa Pedretti, M. Vignati, S. Zucchelli, Jeremy S. Cushman, S. Pirro, L. Gironi, Vladimir Datskov, F. T. Avignone, Ke Han, Reina H. Maruyama, R. Hennings-Yeomans, Stuart J. Freedman, C. Rusconi, Massimiliano Nastasi, Yu-Gang Ma, A. Giuliani, Lindley Winslow, S. Trentalange, Elena Sala, Y. Mei, Yu. G. Kolomensky, Luigi Cappelli, I. Dafinei, Xi-Guang Cao, K. M. Heeger, Marco Pallavicini, G. Pessina, Simone Capelli, R. W. Kadel, Carlo Ligi, A. R. Smith, H. A. Farach, G. Fernandes, S. Morganti, G. Ventura, G. Piperno, Ettore Fiorini, Andrea Giachero, M. L. Di Vacri, S. Copello, Stefano Dell'Oro, X. Liu, European Organization for Nuclear Research (CERN), Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Analyse et de Mathématiques Appliquées (LAMA), Université Paris-Est Marne-la-Vallée (UPEM)-Fédération de Recherche Bézout-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire d'Orsay (IPNO), Cremonesi, O., Artusa, D. R., Avignone, F. T., Azzolini, O., Balata, M., Banks, T. I., Bari, G., Beeman, J., Bellini, F., Bersani, A., Biassoni, M., Brofferio, C., Bucci, C., Camacho, A., Caminata, A., Canonica, L., Cao, X., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Creswick, R. J., Cushman, J. S., Dafinei, I., Dally, A., Datskov, V., Dell’Oro, S., Deninno, M. M., Di Domizio, S., di Vacri, M. L., Drobizhev, A., Ejzak, L., Fang, D. Q., Farach, H. A., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Li, Y. L., Ligi, C., Lim, K. E., Liu, X., Ma, Y. G., Maiano, C., Maino, M., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Napolitano, T., Nastasi, M., Nisi, S., Nones, C., Norman, E. B., Nucciotti, A., O’Donnell, T., Orio, F., Orlandi, D., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pedretti, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sala, E., Sangiorgio, S., Scielzo, N. D., Sisti, M., Smith, A. R., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Trentalange, S., Ventura, G., Vignati, M., Wang, B. S., Wang, H. W., Wielgus, L., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zarra, C., Zhang, G. Q., Zhu, B. X., Zucchelli, S., Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Kearns, E, Feldman, G, Cremonesi, O, Artusa, D, Avignone, F, Azzolini, O, Balata, M, Banks, T, Bari, G, Beeman, J, Bellini, F, Bersani, A, Biassoni, M, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Creswick, R, Cushman, J, Dafinei, I, Dally, A, Datskov, V, Dell'Oro, S, Deninno, M, Di Domizio, S, di Vacri, M, Drobizhev, A, Ejzak, L, Fang, D, Farach, H, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Haller, E, Han, K, Heeger, K, Hennings-Yeomans, R, Hickerson, K, Huang, H, Kadel, R, Keppel, G, Kolomensky, Y, Li, Y, Ligi, C, Lim, K, Liu, X, Ma, Y, Maiano, C, Maino, M, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nisi, S, Nones, C, Norman, E, Nucciotti, A, O'Donnell, T, Orio, F, Orlandi, D, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pedretti, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sala, E, Sangiorgio, S, Scielzo, N, Sisti, M, Smith, A, Taffarello, L, Tenconi, M, Terranova, F, Tomei, C, Trentalange, S, Ventura, G, Vignati, M, Wang, B, Wang, H, Wielgus, L, Wilson, J, Winslow, L, Wise, T, Woodcraft, A, Zanotti, L, Zarra, C, Zhang, G, Zhu, B, and Zucchelli, S

Subjects
Particle physics, Physics - Instrumentation and Detectors, FOS: Physical sciences, 7. Clean energy, 01 natural sciences, Particle identification, VALIDATION, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), Physics and Astronomy (all), neutrino, CUORE, bolometer, Observatory, SIGNALS, Double beta decay, 0103 physical sciences, DETECTORS, [PHYS.COND]Physics [physics]/Condensed Matter [cond-mat], 010306 general physics, Physics, [PHYS]Physics [physics], 010308 nuclear & particles physics, BOLOMETERS, Instrumentation and Detectors (physics.ins-det), CUORICINO, MAJORANA, RADIOACTIVE CONTAMINATION, RARE EVENTS, Neutrino detector, [PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci], inverted hierarchy, NEUTRON, Neutrino, Bolometer, Inverted hierarchy, Radioactive decay
Abstract

With 741 kg of TeO2 crystals and an excellent energy resolution of 5 keV (0.2%) at the region of interest, the CUORE (Cryogenic Underground Observatory for Rare Events) experiment aims at searching for neutrinoless double beta decay of 130Te with unprecedented sensitivity. Expected to start data taking in 2015, CUORE is currently in an advanced construction phase at LNGS. CUORE projected neutrinoless double beta decay half-life sensitivity is 1.6E26 y at 1 sigma (9.5E25 y at the 90% confidence level), in five years of live time, corresponding to an upper limit on the effective Majorana mass in the range 40-100 meV (50-130 meV). Further background rejection with auxiliary bolometric detectors could improve CUORE sensitivity and competitiveness of bolometric detectors towards a full analysis of the inverted neutrino mass hierarchy. CUORE-0 was built to test and demonstrate the performance of the upcoming CUORE experiment. It consists of a single CUORE tower (52 TeO2 bolometers of 750 g each, arranged in a 13 floor structure) constructed strictly following CUORE recipes both for materials and assembly procedures. An experiment its own, CUORE-0 is expected to reach a sensitivity to the neutrinoless double beta decay half-life of 130Te around 3E24 y in one year of live time. We present an update of the data, corresponding to an exposure of 18.1 kg y. An analysis of the background indicates that the CUORE performance goal is satisfied while the sensitivity goal is within reach., 10 pages, 3 figures, to appear in the proceedings of NEUTRINO 2014, 26th International Conference on Neutrino Physics and Astrophysics, 2-7 June 2014, held at Boston, Massachusetts, USA

Published
2015
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45. First neutrinoless double beta decay results from CUORE-0

Author

A. Woodcraft, Massimiliano Clemenza, Carlo Cosmelli, Ettore Fiorini, Andrea Giachero, F. Terranova, Davide Chiesa, K. E. Lim, K. Alfonso, M. L. Di Vacri, G. Bari, Jeffrey W. Beeman, C. Rusconi, Stefano Dell'Oro, G. Piperno, M. Maino, C. Brofferio, X. Liu, A. Dally, D. Santone, H. W. Wang, N. Casali, T. O'Donnell, N. D. Scielzo, Ke Han, Reina H. Maruyama, Stuart J. Freedman, V. Pettinacci, A. Caminata, Ezio Previtali, A. Bersani, L. Taffarello, L. Cardani, T. I. Banks, Oliviero Cremonesi, Guimin Zhang, M. Balata, E. V. Hansen, L. Wielgus, C. Pira, M. M. Deninno, J. L. Ouellet, S. Zucchelli, S. Copello, N. Moggi, G. Fernandes, F. Orio, Paolo Carniti, Lucia Canonica, S. Pirro, F. Bellini, B. X. Zhu, R. Hennings-Yeomans, H. Z. Huang, M. Tenconi, Lindley Winslow, Kevin Hickerson, Samuele Sangiorgio, Stefano Nisi, A. Nucciotti, L. Zanotti, C. J. Davis, S. Morganti, B. S. Wang, C. Bucci, C. Alduino, M. Faverzani, T. D. Gutierrez, Miriam Lucio Martinez, S. L. Wagaarachchi, C. Nones, R. J. Creswick, O. Azzolini, S. Di Domizio, C. Zarra, D. Q. Fang, Simone Capelli, R. W. Kadel, B. K. Fujikawa, L. Gironi, V. Palmieri, Stefano Pozzi, F. T. Avignone, Lorenzo Cassina, Eric B. Norman, Marco Pallavicini, M. Vignati, T. Napolitano, N. Chott, G. Pessina, Claudio Gotti, M. Biassoni, Yu. G. Kolomensky, Luigi Cappelli, M. Pavan, I. Dafinei, Elena Sala, Y. Mei, A. Drobizhev, D. Orlandi, M. A. Franceschi, S. Zimmermann, Xi-Guang Cao, K. M. Heeger, Carlo Ligi, A. R. Smith, G. Ventura, Jeremy S. Cushman, Yu-Gang Ma, C. Rosenfeld, P. Gorla, F. Ferroni, C. Tomei, Emanuele Ferri, Eugene E. Haller, A. Camacho, L. Carbone, C. Pagliarone, T. Wise, A. Giuliani, S. Trentalange, L. Pattavina, James R. Wilson, G. Keppel, D. R. Artusa, Monica Sisti, CSNSM PS1, Centre de Spectrométrie Nucléaire et de Spectrométrie de Masse (CSNSM), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11)-Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Gironi, L., Alduino, C., Alfonso, K., Artusa, D. R., Avignone, F. T., Azzolini, O., Balata, M., Banks, T. I., Bari, G., Beeman, J. W., Bellini, F., Bersani, A., Biassoni, M., Brofferio, C., Bucci, C., Camacho, A., Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., Dafinei, I., Dally, A., Davis, C. J., Dell’Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Ligi, C., Lim, K. E., Liu, X., Ma, Y. G., Maino, M., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Napolitano, T., Nisi, S., Nones, C., Norman, E. B., Nucciotti, A., O’Donnell, T., Orio, F., Orlandi, D., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sala, E., Sangiorgio, S., Santone, D., Scielzo, N. D., Sisti, M., Smith, A. R., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Trentalange, S., Ventura, G., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Wielgus, L., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zarra, C., Zhang, G. Q., Zhu, B. X., Zimmermann, S., Zucchelli, S., Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Civitarese, O, Stekl, I, Suhonen, J, Gironi, L, Alduino, C, Alfonso, K, Artusa, D, Avignone, F, Azzolini, O, Balata, M, Banks, T, Bari, G, Beeman, J, Bellini, F, Bersani, A, Biassoni, M, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, Dafinei, I, Dally, A, Davis, C, Dell'Oro, S, Deninno, M, Di Domizio, S, Di Vacri, M, Drobizhev, A, Fang, D, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Haller, E, Han, K, Hansen, E, Heeger, K, Hennings Yeomans, R, Hickerson, K, Huang, H, Kadel, R, Keppel, G, Kolomensky, Y, Ligi, C, Lim, K, Liu, X, Ma, Y, Maino, M, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nisi, S, Nones, C, Norman, E, Nucciotti, A, O'Donnell, T, Orio, F, Orlandi, D, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sala, E, Sangiorgio, S, Santone, D, Scielzo, N, Sisti, M, Smith, A, Taffarello, L, Tenconi, M, Terranova, F, Tomei, C, Trentalange, S, Ventura, G, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Wielgus, L, Wilson, J, Winslow, L, Wise, T, Woodcraft, A, Zanotti, L, Zarra, C, Zhang, G, Zhu, B, Zimmermann, S, and Zucchelli, S

Subjects
01 natural sciences, 7. Clean energy, law.invention, Nuclear physics, double-beta decay: neutrinoless | bolometer | Gran Sasso | energy resolution | sensitivity | background | CUORE Author supplied: Bolometers | Double beta decay | Isotopes | Laboratory procedures, Physics and Astronomy (all), CUORE, law, Double beta decay, 0103 physical sciences, LABORATORI nazionali del Gran Sasso (Italy). Laboratory for Underground Nuclear Astrophysics, Bolometers, Double Beta Decay, Isotopes, Laboratory procedures, [PHYS.COND]Physics [physics]/Condensed Matter [cond-mat], 010303 astronomy & astrophysics, Physics, [PHYS]Physics [physics], Neutrinoless double beta decay, TeO2, bolometers, 010308 nuclear & particles physics, BOLOMETERS, Bolometer, Background level, Massless particle, NEUTRINOLESS double beta decay, ISOTOPES, Neutrino, Radioactive decay, Lepton, SENSITIVITY analysis
Abstract

International audience; The CUORE-0 experiment, a 52 bolometer array searching for neutrinoless double beta decay from 130Te, has started taking data in spring 2013 underground at the Laboratori Nazionali del Gran Sasso (LNGS). The excellent results obtained in terms of energy resolution and background level allowed this experiment to reach the sensitivity of Cuoricino in approximately half the runtime. Combining CUORE-0 data (9.8 kg·yr exposure of 130Te) with the 19.75 kg·yr exposure of the Cuoricino experiment, we obtain the most stringent limit to date on the half-life of this isotope (T1/2 > 4.0 × 1024 yr). In this article, we review the results from CUORE-0 and discuss the status and the physics potential of CUORE, a 19 times larger bolometer array that plans to begin operations by end of this year.

Published
2015
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46. The CUORE and CUORE-0 experiments at Gran Sasso

Author

Jeremy S. Cushman, S. Copello, G. Piperno, H. Z. Huang, Davide Chiesa, K. E. Lim, A. Caminata, R. W. Kadel, L. Taffarello, Ettore Fiorini, S. Zucchelli, Andrea Giachero, B. X. Zhu, A. Woodcraft, Oliviero Cremonesi, Massimiliano Clemenza, Carlo Cosmelli, W. D. Tian, A. Bersani, G. Ventura, B. S. Wang, Ezio Previtali, Jonathan Ouellet, M. L. Di Vacri, G. Bari, S. Morganti, H. A. Farach, N. Moggi, Deqing Fang, S. Dell'Oro, X. Z. Cai, A. Giuliani, G. Fernandes, S. Di Domizio, C. Brofferio, Samuele Sangiorgio, Xiangyu Cao, T. D. Gutierrez, F. Terranova, X. Liu, Carlo Ligi, T. I. Banks, A. Nucciotti, C. Zarra, L. Pattavina, V. Rampazzo, Marco Pallavicini, M. I. Martínez, M. Tenconi, Yan Li, Yu G. Kolomensky, M. Balata, Francesca Bellini, A. Drobizhev, L. Cappelli, B. K. Fujikawa, G. Pessina, M. Biassoni, Elena Sala, Stefano Pozzi, S. Trentalange, T. Napolitano, D. Orlandi, Y. Mei, R. Hennings-Yeomans, C. Rosenfeld, Marisa Pedretti, Nicholas Scielzo, M. A. Franceschi, M. Vignati, K. M. Heeger, N. Casali, Guoqiang Zhang, M. Pavan, K. Kazkaz, Alejandro E. Camacho, Hongwei Wang, Ke Han, Reina H. Maruyama, Stuart J. Freedman, C. Pira, L. Gironi, F. T. Avignone, Larissa M. Ejzak, Claudio Gotti, Vladimir Datskov, I. Dafinei, L. Cassina, Yu-Gang Ma, L. Canonica, Kevin Hickerson, N. Chott, C. Bucci, M. M. Deninno, L. Carbone, C. Pagliarone, T. Wise, Silvia Capelli, Massimiliano Nastasi, F. Orio, S. Nisi, James R. Wilson, Alan R. Smith, G. Keppel, D. R. Artusa, Monica Sisti, J. W. Beeman, C. Rusconi, M. Faverzani, V. Pettinacci, A. Dally, L. Cardani, Stefano Pirro, Eric B. Norman, Lindley Winslow, Claudia Tomei, O. Azzolini, L. Wielgus, C. Nones, R. J. Creswick, P. Gorla, F. Ferroni, Emanuele Ferri, Eugene E. Haller, L. Zanotti, M. Maino, T. O'Donnell, C. Maiano, European Organization for Nuclear Research (CERN), CSNSM PS1, Centre de Spectrométrie Nucléaire et de Spectrométrie de Masse (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), DAM Île-de-France (DAM/DIF), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11)-Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Giachero, A., Artusa, D.R., Avignone, F.T., Azzolini, O., Balata, M., Banks, T.I., Bari, G., Beeman, J., Bellini, F., Bersani, A., Biassoni, M., Brofferio, C., Bucci, C., Cai, X.Z., Camacho, A., Caminata, A., Canonica, L., Cao, X.G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R.J., Cushman, J.S., Dafinei, I., Dally, A., Datskov, V., Dell'Oro, S., Deninno, M.M., Di Domizio, S., Di Vacri, M.L., Drobizhev, A., Ejzak, L., Fang, D.Q., Farach, H.A., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M.A., Freedman, S.J., Fujikawa, B.K., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T.D., Haller, E.E., Han, K., Heeger, K.M., Hennings-Yeomans, R., Hickerson, K.P., Huang, H.Z., Kadel, R., Kazkaz, K., Keppel, G., Kolomensky, Yu.G., Li, Y.L., Ligi, C., Lim, K.E., Liu, X., Ma, Y.G., Maiano, C., Maino, M., Martinez, M., Maruyama, R.H., Mei, Y., Moggi, N., Morganti, S., Napolitano, T., Nastasi, M., Nisi, S., Nones, C., Norman, E.B., Nucciotti, A., O'Donnell, T., Orio, F., Orlandi, D., Ouellet, J.L., Pagliarone, C.E., Pallavicini, M., Pattavina, L., Pavan, M., Pedretti, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rampazzo, V., Rosenfeld, C., Rusconi, C., Sala, E., Sangiorgio, S., Scielzo, N.D., Sisti, M., Smith, A.R., Taffarello, L., Tenconi, M., Terranova, F., Tian, W.D., Tomei, C., Trentalange, S., Ventura, G., Vignati, M., Wang, B.S., Wang, H.W., Wielgus, L., Wilson, J., Winslow, L.A., Wise, T., Woodcraft, A., Zanotti, L., Zarra, C., Zhang, G.Q., Zhu, B.X., Zucchelli, S., Bravina, L., Giachero, A, Artusa, D, Avignone, F, Azzolini, O, Balata, M, Banks, T, Bari, G, Beeman, J, Bellini, F, Bersani, A, Biassoni, M, Brofferio, C, Bucci, C, Cai, X, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, Dafinei, I, Dally, A, Datskov, V, Dell'Oro, S, Deninno, M, Di Domizio, S, Di Vacri, M, Drobizhev, A, Ejzak, L, Fang, D, Farach, H, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Haller, E, Han, K, Heeger, K, Hennings Yeomans, R, Hickerson, K, Huang, H, Kadel, R, Kazkaz, K, Keppel, G, Kolomensky, Y, Li, Y, Ligi, C, Lim, K, Liu, X, Ma, Y, Maiano, C, Maino, M, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nisi, S, Nones, C, Norman, E, Nucciotti, A, O'Donnell, T, Orio, F, Orlandi, D, Ouellet, J, Pagliarone, C, Pallavicini, M, Pattavina, L, Pavan, M, Pedretti, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rampazzo, V, Rosenfeld, C, Rusconi, C, Sala, E, Sangiorgio, S, Scielzo, N, Sisti, M, Smith, A, Taffarello, L, Tenconi, M, Terranova, F, Tian, W, Tomei, C, Trentalange, S, Ventura, G, Vignati, M, Wang, B, Wang, H, Wielgus, L, Wilson, J, Winslow, L, Wise, T, Woodcraft, A, Zanotti, L, Zarra, C, Zhang, G, Zhu, B, and Zucchelli, S

Subjects
Physics, [PHYS]Physics [physics], Physics - Instrumentation and Detectors, QC1-999, Bolometer, FOS: Physical sciences, Instrumentation and Detectors (physics.ins-det), VALIDATION, law.invention, Nuclear physics, CONTAMINATION, Physics and Astronomy (all), CUORE, activity report | double-beta decay: (0neutrino) | CUORE | bolometer | sensitivity | performance | tellurium: nuclide | experimental results, Observatory, law, Double beta decay, [PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci], DOUBLE-BETA DECAY, [PHYS.COND]Physics [physics]/Condensed Matter [cond-mat], physics.ins-det, K OUTER CRYOSTAT, Bolometers, neutrinoless double beta decay
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is an experiment to search for neutrinoless double beta decay ($0\nu\beta\beta$) in $^{130}$Te and other rare processes. CUORE is a cryogenic detector composed of 988 TeO$_2$ bolometers for a total mass of about 741 kg. The detector is being constructed at the Laboratori Nazionali del Gran Sasso, Italy, where it will start taking data in 2015. If the target background of 0.01 counts/(keV$\cdot$kg$\cdot$y) will be reached, in five years of data taking CUORE will have an half life sensitivity around $1\times 10^{26}$ y at 90\% C.L. As a first step towards CUORE a smaller experiment CUORE-0, constructed to test and demonstrate the performances expected for CUORE, has been assembled and is running. The detector is a single tower of 52 CUORE-like bolometers that started taking data in spring 2013. The status and perspectives of CUORE will be discussed, and the first CUORE-0 data will be presented., Comment: Proceedings of a talk given at the International Conference of New Frontiers in Physics, ICNFP 2014; submitted at EPJ Web of Conferences

Published
2015
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47. First data from CUORE-0

Author

Ettore Fiorini, Andrea Giachero, S. Di Domizio, Y. L. Li, W. D. Tian, L. Wielgus, M. L. Di Vacri, D. Orlandi, C. Zarra, M. Tenconi, S. Zucchelli, B. X. Zhu, X. Liu, N. Chott, Alan R. Smith, M. A. Franceschi, B. K. Fujikawa, V. Rampazzo, R. J. Creswick, F. Orio, C. Rusconi, C. Rosenfeld, Kareem Kazkaz, Davide Chiesa, Massimiliano Clemenza, Carlo Cosmelli, P. Gorla, F. Ferroni, C. Tomei, Emanuele Ferri, Eugene E. Haller, A. De Biasi, T. I. Banks, Oliviero Cremonesi, J. Goett, A. Giuliani, K. E. Lim, A. Camacho, B. S. Wang, L. Cardani, C. Pira, Jeffrey W. Beeman, G. Bari, S. Pirro, A. Dally, A.M. Vignati, V. Palmieri, O. Azzolini, Pedretti, Larissa M. Ejzak, S. Trentalange, C. Brofferio, C. Maiano, L. Gironi, F. T. Avignone, A. Bersani, D. Q. Fang, Ioan Dafinei, M. M. Deninno, James R. Wilson, Eric B. Norman, Silvio Morganti, T. Napolitano, L. Taffarello, Carlo Ligi, M. Carrettoni, M. Maino, Lucia Canonica, G. Keppel, Nicholas Scielzo, D. R. Artusa, M. I. Martínez, Monica Sisti, F. Bellini, H. W. Wang, M. Biassoni, Lindley Winslow, G. Ventura, T. O'Donnell, X. Z. Cai, Ezio Previtali, G. Piperno, Claudio Gotti, C. P. Aguirre, H. A. Farach, N. Casali, L. Zanotti, C. Bucci, T. D. Gutierrez, Vladimir Datskov, J. L. Ouellet, Yu-Gang Ma, Ke Han, Reina H. Maruyama, M. Pavan, Stuart J. Freedman, M. Balata, T. Wise, N. Moggi, Elena Sala, Y. Mei, L. Carbone, Simone Capelli, R. W. Kadel, C. Nones, R. Hennings-Yeomans, Xi-Guang Cao, Yu. G. Kolomensky, K. M. Heeger, A. Woodcraft, Samuele Sangiorgio, Stefano Nisi, F. Terranova, A. Nucciotti, M. Faverzani, Marco Pallavicini, G. Fernandes, G. Pessina, H. Z. Huang, L. Pattavina, A.M. Vignati, C.P. Aguirre, D.R. Artusa, F.T. Avignone III, O. Azzolini, M. Balata, T.I. Bank, G. Bari, J. Beeman, F. Bellini, A. Bersani, M. Biassoni, C. Brofferio, C. Bucci, X.Z. Cai, A. Camacho, L. Canonica, X. Cao, S. Capelli, L. Carbone, L. Cardani, M. Carrettoni, N. Casali, D. Chiesa, N. Chott, M. Clemenza, C. Cosmelli, O. Cremonesi, R.J. Creswick, I. Dafinei, A. Dally, V. Datskov, A. De Biasi, M.M. Deninno, S. Di Domizio, M.L. di Vacri, L. Ejzak, D.Q. Fang, H.A. Farach, M. Faverzani, G. Fernande, E. Ferri, F. Ferroni, E. Fiorini, M.A. Franceschi, S.J. Freedman, B.K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, J. Goett, P. Gorla, C. Gotti, T.D. Gutierrez, E.E. Haller, K. Han, K.M. Heeger, R. Hennings-Yeoman, H.Z. Huang, R. Kadel, K. Kazkaz, G. Keppel, Yu.G. Kolomensky, Y.L. Li, C. Ligi, K.E. Lim, X. Liu, Y.G. Ma, C. Maiano, M. Maino, M. Martinez, R.H. Maruyama, Y. Mei, N. Moggi, S. Morganti, T. Napolitano, S. Nisi, C. None, E.B. Norman, A. Nucciotti, T. O’Donnell, F. Orio, D. Orlandi, J.L. Ouellet, M. Pallavicini, V. Palmieri, L. Pattavina, M. Pavan, Pedretti, G. Pessina, G. Piperno, C. Pira, S. Pirro, E. Previtali, V. Rampazzo, C. Rosenfeld, C. Rusconi, E. Sala, S. Sangiorgio, N.D. Scielzo, M. Sisti, A.R. Smith, L. Taffarello, M. Tenconi, F. Terranova, W.D. Tian, C. Tomei, S. Trentalange, G. Ventura, B.S. Wang, H.W. Wang, L. Wielgu, J. Wilson, L.A. Winslow, T. Wise, A. Woodcraft, L. Zanotti, C. Zarra, B.X. Zhu, S. Zucchelli, Vignati, A, Aguirre, C, Artusa, D, Avignone, F, Azzolini, O, Balata, M, Banks, T, Bari, G, Beeman, J, Bellini, F, Bersani, A, Biassoni, M, Brofferio, C, Bucci, C, Cai, X, Camacho, A, Canonica, L, Cao, X, Capelli, S, Carbone, L, Cardani, L, Carrettoni, M, Casali, N, Chiesa, D, Chott, N, Clemenza, M, Cosmelli, C, Cremonesi, O, Creswick, R, Dafinei, I, Dally, A, Datskov, V, De Biasi, A, Deninno, M, Di Domizio, S, Di Vacri, M, Ejzak, L, Fang, D, Farach, H, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Goett, J, Gorla, P, Gotti, C, Gutierrez, T, Haller, E, Han, K, Heeger, K, Hennings Yeomans, R, Huang, H, Kadel, R, Kazkaz, K, Keppel, G, Kolomensky, Y, Li, Y, Ligi, C, Lim, K, Liu, X, Ma, Y, Maiano, C, Maino, M, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nisi, S, Nones, C, Norman, E, Nucciotti, A, O'Donnell, T, Orio, F, Orlandi, D, Ouellet, J, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pedretti, N, Pessina, G, Piperno, G, Pira, C, Pirro, S, Previtali, E, Rampazzo, V, Rosenfeld, C, Rusconi, C, Sala, E, Sangiorgio, S, Scielzo, N, Sisti, M, Smith, A, Taffarello, L, Tenconi, M, Terranova, F, Tian, W, Tomei, C, Trentalange, S, Ventura, G, Wang, B, Wang, H, Wielgus, L, Wilson, J, Winslow, L, Wise, T, Woodcraft, A, Zanotti, L, Zarra, C, Zhu, B, and Zucchelli, S

Subjects
Physics, CUORE, bolometer, BOLOMETERS, Bolometer, Detector, half live, double beta decay, Physics and Astronomy(all), law.invention, Nuclear physics, neutrino, FIS/01 - FISICA SPERIMENTALE, law, Double beta decay, radioactivity, Sensitivity (control systems), Neutrino
Abstract

CUORE-0 is an experiment built to test and demonstrate the performance of the upcoming CUORE experiment. Com- posed of 52 TeO2 bolometers of 750g each, it is expected to reach a sensitivity to the 0νββ half-life of 130Te around 3 · 1024 y in one year of live time. We present the first data, corresponding to an exposure of 7.1kg y. An analysis of the background indicates that the CUORE sensitivity goal is within reach, validating our techniques to reduce the α radioactivity of the detector.

Published
2015

48. Lowering the CUORE energy threshold

Author

M. Faverzani, Yu. G. Kolomensky, Luigi Cappelli, Jeremy S. Cushman, Massimiliano Clemenza, Carlo Cosmelli, L. Gladstone, N. Casali, E. V. Hansen, A. Woodcraft, Lorenzo Cassina, Ke Han, A. Branca, Reina H. Maruyama, F. Terranova, Stuart J. Freedman, R. J. Creswick, L. Carbone, C. Pagliarone, Y. Mei, I. Dafinei, T. Wise, N. Moggi, V. Palmieri, C. Brofferio, P. J. Mosteiro, S. L. Wagaarachchi, K. M. Heeger, L. Gironi, Samuele Sangiorgio, A. Drobizhev, C. Rosenfeld, S. Zucchelli, A. Nucciotti, Eric B. Norman, Guimin Zhang, C. Alduino, Stefano Dell'Oro, S. Pirro, Simone Capelli, R. W. Kadel, T. Napolitano, Oliviero Cremonesi, A. Caminata, M. A. Franceschi, S. Zimmermann, P. Gorla, F. Ferroni, Marco Pallavicini, C. Rusconi, Jonathan Ouellet, M. M. Deninno, H. Z. Huang, C. Pira, M. Tenconi, C. Tomei, F. Orio, A. Giuliani, G. Pessina, Emanuele Ferri, Eugene E. Haller, T. I. Banks, M. Biassoni, G. Bari, X. Liu, L. Pattavina, S. Morganti, Avignone, F. T., Iii., B. S. Wang, S. Trentalange, G. Piperno, A. Camacho, S. Di Domizio, F. Bellini, O. Azzolini, Ettore Fiorini, B. K. Fujikawa, C. Nones, Stefano Pozzi, C. Bucci, T. D. Gutierrez, M. Pavan, M. Maino, Miriam Lucio Martinez, V. Pettinacci, R. Hennings-Yeomans, H. W. Wang, A. D'Addabbo, M. Vignati, T. O'Donnell, L. Cardani, Carlo Ligi, A. Giachero, A. R. Smith, X. G. Cao, James R. Wilson, L. Taffarello, K. Alfonso, G. Fernandes, G. Keppel, D. R. Artusa, Virendra Singh, M. L. Di Vacri, B. X. Zhu, Monica Sisti, D. Q. Fang, N. Chott, C. J. Davis, Yu-Gang Ma, S. Copello, Paolo Carniti, Lindley Winslow, Claudio Gotti, Davide Chiesa, K. E. Lim, Jeffrey W. Beeman, A. Bersani, L. Zanotti, A. Leder, D. Santone, N. D. Scielzo, E. Previtali, L. Canonica, L. Marini, Kevin Hickerson, Copello, S, Alduino, C, Alfonso, K, Artusa, D, Avignone, F, Azzolini, O, Banks, T, Bari, G, Beeman, J, Bellini, F, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D'Addabbo, A, Dafinei, I, Davis, C, Dell'Oro, S, Deninno, M, Di Domizio, S, Di Vacri, M, Drobizhev, A, Fang, D, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Haller, E, Han, K, Hansen, E, Heeger, K, Hennings-Yeomans, R, Hickerson, K, Huang, H, Kadel, R, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Liu, X, Ma, Y, Maino, M, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Mosteiro, P, Napolitano, T, Nones, C, Norman, E, Nucciotti, A, O'Donnell, T, Orio, F, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sangiorgio, S, Santone, D, Scielzo, N, Singh, V, Sisti, M, Smith, A, Taffarello, L, Tenconi, M, Terranova, F, Tomei, C, Trentalange, S, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Wilson, J, Winslow, L, Wise, T, Woodcraft, A, Zanotti, L, Zhang, G, Zhu, B, Zimmermann, S, Zucchelli, S, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Département de Physique des Particules (ex SPP) (DPhP), Copello, S., Alduino, C., Alfonso, K., Artusa, D. R., Avignone, F. T., Azzolini, O., Banks, T. I., Bari, G., Beeman, J. W., Bellini, F., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., A., Camacho, Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., D'Addabbo, A., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., G., Fernande, Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Liu, X., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Napolitano, T., Nones, C., Norman, E. B., Nucciotti, A., O'Donnell, T., Orio, F., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C. C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sangiorgio, S., Santone, D., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Trentalange, S., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zhu, B. X., S., Zimmermann, and Zucchelli, S.

Subjects
History, Particle physics, Physics::Instrumentation and Detectors, dark matter: direct detection, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], 01 natural sciences, Education, Physics and Astronomy (all), energy: threshold, Low energy, CUORE, double-beta decay: (0neutrino), bolometer, Double beta decay, 0103 physical sciences, semiconductor counter, 010306 general physics, detector: design, energy: low, Physics, 010308 nuclear & particles physics, Astrophysics::Instrumentation and Methods for Astrophysics, Energy: threshold | trigger: efficiency | dark matter: direct detection | axion: solar | energy: low | CUORE | double-beta decay | Gran Sasso | bolometer | observatory | calibration | sensitivity | performance | background | cryogenics, calibration, Gran Sasso, Computer Science Applications, Continuous data, cryogenics, trigger: efficiency, electronics: readout, axion: solar, National laboratory, tellurium compounds, Tellurium compounds, Data selection
Abstract

Author(s): Copello, S; Alduino, C; Alfonso, K; Artusa, DR; Avignone, FT; Azzolini, O; Banks, TI; Bari, G; Beeman, JW; Bellini, F; Bersani, A; Biassoni, M; Branca, A; Brofferio, C; Bucci, C; Camacho, A; Caminata, A; Canonica, L; Cao, XG; Capelli, S; Cappelli, L; Carbone, L; Cardani, L; Carniti, P; Casali, N; Cassina, L; Chiesa, D; Chott, N; Clemenza, M; Cosmelli, C; Cremonesi, O; Creswick, RJ; Cushman, JS; D'Addabbo, A; Dafinei, I; Davis, CJ; Dell'Oro, S; Deninno, MM; Di Domizio, S; Di Vacri, ML; Drobizhev, A; Fang, DQ; Faverzani, M; Fernandes, G; Ferri, E; Ferroni, F; Fiorini, E; Franceschi, MA; Freedman, SJ; Fujikawa, BK; Giachero, A; Gironi, L; Giuliani, A; Gladstone, L; Gorla, P; Gotti, C; Gutierrez, TD; Haller, EE; Han, K; Hansen, E; Heeger, KM; Hennings-Yeomans, R; Hickerson, KP; Huang, HZ; Kadel, R; Keppel, G; Kolomensky, YG; Leder, A; Ligi, C; Lim, KE; Liu, X; Ma, YG; Maino, M; Marini, L; Martinez, M; Maruyama, RH; Mei, Y; Moggi, N; Morganti, S; Mosteiro, PJ; Napolitano, T; Nones, C; Norman, EB; Nucciotti, A; O'Donnell, T | Abstract: The Cryogenic Underground Observatory for Rare Events (CUORE) is a ton-scale double beta decay experiment based on TeO2 cryogenic bolometers and is currently in the last construction stage at the Gran Sasso National Laboratory (LNGS). Its primary goal is to observe neutrino-less double beta decay of 130Te, however thanks to the ultra-low background and large projected exposure it could also be suitable for other rare event searches, as the detection of solar axions, neutrinos from type II supernovae or direct detection of dark matter. The sensitivity for these searches will depend on the performance achieved at the low energy threshold. For this reason a trigger algorithm based on continuous data filtering has been developed which will allow lowering the threshold down to the few keV region. The new trigger has been tested in CUORE-0, a single-tower CUORE prototype consisting of 52 TeO2 bolometers and recently concluded, and here we present the results in terms of trigger efficiency, data selection and low-energy calibration.

Published
2017
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49. Contamination of breast milk obtained by manual expression and breast pumps in mothers of very low birthweight infants

Author

N-Y. Boo, Hanafiah Alfizah, A J Nordiah, V. K. E. Lim, and A.H. Nor-Rohaini

Subjects
Adult, Male, Microbiology (medical), medicine.medical_specialty, Vlbw infants, education, Mammary gland, Food Contamination, Breast milk, law.invention, law, Intensive Care Units, Neonatal, Humans, Infant, Very Low Birth Weight, Medicine, skin and connective tissue diseases, Bacteria, Milk, Human, business.industry, Obstetrics, Infant, Newborn, General Medicine, Contamination, Manual expression, Surgery, Infectious Diseases, medicine.anatomical_structure, Female, Infant Food, Breast pump, business, Breast feeding, Food contaminant
Abstract

The objective of this study was to compare the rates of bacterial contamination of expressed breast milk (EBM) obtained by manual expression and breast pumps in mothers of very low birthweight (VLBW) infants (

Published
2001
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50. The CUORE and CUORE-0 experiments at LNGS

Author

Guimin Zhang, C. Pira, R. J. Creswick, A. Leder, S. Di Domizio, V. Pettinacci, B. X. Zhu, Stefano Pirro, Laura Cardani, D. Santone, J. S. Wilson, Ioan Dafinei, C. Rosenfeld, Stefano Dell'Oro, P. Gorla, L. Pattavina, F. Ferroni, C. Tomei, S. L. Wagaarachchi, E. V. Hansen, C. Cosmelli, B. K. Fujikawa, Emanuele Ferri, X. Liu, F. Orio, L. Carbone, S. Zimmermann, C. Pagliarone, Yu. G. Kolomensky, Luigi Cappelli, A. Bersani, G. Keppe, G. Pessina, C. J. Davis, Massimiliano Clemenza, R. Hennings-Yeomans, S. Pozzi, A. Camacho, Monica Sisti, N. Moggi, B. S. Wang, C. Rusconi, T. Wise, C. Brofferio, P. J. Mosteiro, T. I. Banks, M. M. Deninno, M. Vignati, C. Nones, O. Azzolini, G. Piperno, Samuele Sangiorgio, A. Nucciotti, M. Pavan, H. W. Wang, N. D. Scielzo, Stefano Zucchelli, N. Chott, C. Alduino, M. Faverzani, L. Taffarello, Lucia Canonica, F. Bellini, L. Zanotti, Davide Chiesa, K. Alfonso, M. L. Di Vacri, K. E. Lim, Lorenzo Cassina, V. Singh, C. Bucci, Miriam Lucio Martinez, Lindley Winslow, M. Maino, Jeffrey W. Beeman, H. Z. Huang, M. Tenconi, L. Marini, Kevin Hickerson, S. Copello, E. Fiorini, Silvia Capelli, Paolo Carniti, A. D'Addabbo, A. Giuliani, Jonathan Ouellet, L. Gironi, F. T. Avignone, S. J. Freedman, G. Bari, S. Trentalange, R. W. Kadel, A. Caminata, Ezio Previtali, Marco Pallavicini, G. Fernandes, D. R. Artusa, S. Morganti, Jeremy S. Cushman, Carlo Ligi, A. R. Smith, C. Gotti, A. Woodcraft, A. Giachero, D. Q. Fang, L. Gladstone, T. D. Gutierrez, F. Terranova, A. Drobizhev, M. A. Franceschi, Y. Mei, Xi-Guang Cao, K. M. Heeger, E. E. Haller, Ke Han, A. Branca, Reina H. Maruyama, N. Casali, Oliviero Cremonesi, T. O'Donnell, Yu-Gang Ma, V. Palmieri, Eric B. Norman, T. Napolitano, M. Biassoni, Bravina, L, Foka, Y, Kabana, S, D'Addabbo, A, Alduino, C, Alfonso, K, Artusa, D, Avignone, F, Azzolini, O, Banks, T, Bari, G, Beeman, J, Bellini, F, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, Dafinei, I, Davis, C, Dell'Oro, S, Deninno, M, Di Domizio, S, Di Vacri, M, Drobizhev, A, Fang, D, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Haller, E, Han, K, Hansen, E, Heeger, K, Hennings-Yeomans, R, Hickerson, K, Huang, H, Kadel, R, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Liu, X, Ma, Y, Maino, M, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Mosteiro, P, Napolitano, T, Nones, C, Norman, E, Nucciotti, A, O'Donnell, T, Orio, F, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sangiorgio, S, Santone, D, Scielzo, N, Singh, V, Sisti, M, Smith, A, Taffarello, L, Tenconi, M, Terranova, F, Tomei, C, Trentalange, S, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Wilson, J, Winslow, L, Wise, T, Woodcraft, A, Zanotti, L, Zhang, G, Zhu, B, Zimmermann, S, Zucchelli, S, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), D'Addabbo, A., Bravina, L., Alduino, C., Alfonso, K., Artusa, D. R., Avignone, F. T., Azzolini, O., Banks, T. I., Bari, G., Beeman, J. W., Bellini, F., Bersani, A., Biassoni, M., Branca, A., Brofferio, C., Bucci, C., A., Camacho, Caminata, A., Canonica, L., Cao, X. G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Carniti, P., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R. J., Cushman, J. S., Dafinei, I., Davis, C. J., Dell'Oro, S., Deninno, M. M., Di Domizio, S., Di Vacri, M. L., Drobizhev, A., Fang, D. Q., Faverzani, M., G., Fernande, Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M. A., Freedman, S. J., Fujikawa, B. K., Giachero, A., Gironi, L., Giuliani, A., Gladstone, L., Gorla, P., Gotti, C., Gutierrez, T. D., Haller, E. E., Han, K., Hansen, E., Heeger, K. M., Hennings-Yeomans, R., Hickerson, K. P., Huang, H. Z., Kadel, R., Keppel, G., Kolomensky, Yu. G., Leder, A., Ligi, C., Lim, K. E., Liu, X., Ma, Y. G., Maino, M., Marini, L., Martinez, M., Maruyama, R. H., Mei, Y., Moggi, N., Morganti, S., Mosteiro, P. J., Napolitano, T., Nones, C., Norman, E. B., Nucciotti, A., O'Donnell, T., Orio, F., Ouellet, J. L., Pagliarone, C. E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, S., Previtali, E., Rosenfeld, C., Rusconi, C., Sangiorgio, S., Santone, D., Scielzo, N. D., Singh, V., Sisti, M., Smith, A. R., Taffarello, L., Tenconi, M., Terranova, F., Tomei, C., Trentalange, S., Vignati, M., Wagaarachchi, S. L., Wang, B. S., Wang, H. W., Wilson, J., Winslow, L. A., Wise, T., Woodcraft, A., Zanotti, L., Zhang, G. Q., Zhu, B. X., S., Zimmermann, Zucchelli, S., Centre de Sciences Nucléaires et de Sciences de la Matière ( CSNSM ), Université Paris-Sud - Paris 11 ( UP11 ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Département de Physique des Particules (ex SPP) ( DPP ), Institut de Recherches sur les lois Fondamentales de l'Univers ( IRFU ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay, and Département de Physique des Particules (ex SPP) (DPhP)

Subjects
Cryostat, Physics - Instrumentation and Detectors, QC1-999, FOS: Physical sciences, double beta decay, Te-130, fabrication, 7. Clean energy, 01 natural sciences, tellurium: oxygen, crystal, law.invention, Nuclear physics, Physics and Astronomy (all), CUORE, bolometer, law, Observatory, Double Beta Decay: 0 neutrino | CUORE Experiment | | CUORE-0 Experiment | Activity report | performance | bolometer | cryogenics | crystal | tellurium: oxygen | fabrication, 0103 physical sciences, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, [ PHYS.PHYS.PHYS-INS-DET ] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010303 astronomy & astrophysics, activity report, Physics, Bolometer, Instrumentation and Detectors (physics.ins-det), cryogenics, performance
Abstract

The Cryogenic Underground Observatory for Rare Events (CUORE) is a 1-ton scale bolometric experiment devoted to the search of the neutrinoless double-beta decay (0{\nu}\b{eta}\b{eta}) in 130Te. The CUORE detector consists of an array of 988 TeO2 crystals operated at 10 mK. CUORE-0 is the CUORE demonstrator: it has been built to test the performance of the upcoming CUORE experiment and represents the largest 130Te bolometric setup ever operated. CUORE-0 has been running at Laboratori Nazionali del Gran Sasso (Italy) from 2013 to 2015. The final CUORE-0 analysis on 0{\nu}\b{eta}\b{eta} and the corresponding detector performance are presented. The present status of the CUORE experiment, now in its final construction and commissioning phase, are discussed. The results from assembly of the detector and the commissioning of the cryostat are reported., Comment: 10 pages, 7 figures, ICNFP2016 Proceeding

Published
2017
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