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The 60 cases of primary renal pelvic and ureteral tumors treated at Mie University hospitals between January 1977 and December 1987 were reviewed and factors predicting the prognosis were investigated. The patients consisted of 47 men and 13 women (3.6: 1.0). Their ages ranged from 38 to 82 years with a mean of 65.2 years. According to Akaza's category classification of the ureteropelvic tumor, 42 cases were classified to category A, 15 cases category B and 1 case was classified to category C. Histologically, 59 transitional cell carcinomas and 1 squamous cell carcinoma were found. As to grading, 5 was G1, 31 G2, 21 G3 and 2 GX. As to staging, 20 were pT1, 10 pT2, 21 pT3, 3 pT4 and 6 pTX. Staging was correlated well with grading. Total nephroureterectomy with bladder cuff was performed on 39 patients and the other surgical treatments were done on 15 patients. Recurrence of the bladder tumor was found in 22.4%. The 5-year survival rate (Kaplan-Meier's method) was 47.8% for all of the patients. Among the patients with transitional cell carcinoma, the 5-year survival rate was 100% for G1, 57.6% for G2 and 28.6% for G3. As to staging the 5-year survival rate was 90.0% for below pT1, 20.0% for pT2 and 41.1% for pT3. The results from the present study suggest the prognosis is decided by grade and stage in pelvic and ureteral tumors, and it is wanted to develop a system of postoperative adjuvant therapy.

Effects of nickel and chromium contents on weldability of high tensile manganese-silicon steels were investigated. Fourteen experimental ingots which contained 0.06 to 0.93% nickel and 0.03 to 0.91% chromium added to a base composition of 0.16% carbon, 1.10% manganess, and 0.45% silicon, were made by melting in an approximately 700kg acid-lined, high frequency furnace and rolled into 20mm plate. Four commercial heats which were made in a 40ton capacity basic open hearth were tested together for comparison.Various weldability tests ; namely, tensile test, V-Charpy impact tests, Weld-maximum hardness test, Jominy test, kommerell test, Kinzel test, Slit-type cracking type, CTS cracking test, Gas cut bend test, and Fillet-weld break test were used.From the results of tensile and V-Carpy test described in the present paper, the following conclusions have been obtained ;1. The tensile strength increased at a rate of approximately 3kg/m2 per 1% increase of nickel both in as rolled and normalized conditions, and 3kg/mm2 in as rolled condition anp 6kg/mm2 in as normalized condition per 1% increase of chromium.2. Nickel increased the yield strength at a rate of approximately 4 to 5kg/mm2 per 1% increase while chromium showed no effect.3. The energy transition temperature in V-Charpy test was lowered by nickel addition, but was raised by chromium. However, distinct relationships were not found between the 15ft-lb transition temperatures and those alloying contents.4. The effect of nickel or chromium content on the tensile and yield strengths was very slight, provided the contents were limited in a range of nickel less than 0.25% and chromium less than 0.10%. However, the 15ft-lb transition temperature seems to be lowered slightly and the tensile elongation to be increased appreciably when the contents of nickel and chromium were reduced extremely, but the energy or shear fracture transition temperature is not affected.

Herein we report a 26-year-old patient in whom seminoma developed in the testicle which had been fixed 9 years earlier. Thirty five of such cases in the Japanese literature are reviewed.

Clomiphene citrate therapy was performed on 30 patients with idiopathic male infertility, who were intractable to non-hormonal therapy. Clomiphene citrate was administered orally at a dose of 25 mg per day for 25 days with 5 days of rest following Paulson' protocol, and we favorable results were obtained: Both sperm count and sperm motility improved in 11 cases (36.7%). Odera's score count decreased in 14 cases (46.7%), which were judged as effective. The wives of 4 patients treated by this therapy became pregnant. After this therapy, the serum levels of luteinizing hormone, follicle stimulating hormone, testosterone and prolactin were 1.90, 1.81, 1.89 and 1.22 times higher, respectively. These findings indicate that clomiphene citrate therapy is an effective for idiopathic male infertility, but we need to consider that the sudden and marked elevation of serum testosterone level by this therapy might affect male accessory sex organs such as the prostatic gland which shows androgen dependency later in life.

A 57-year-old woman visited the Mie University Hospital with the complaint of lower abdominal pain on December 2, 1987. Cystoscopic examination revealed a non-papillary tumor with a broad base in the left posterior wall. A diagnosis was made by biopsy of the bladder epithelium. Amyloid fibrils were confirmed in the biopsy specimen with polarization and electron microscopies. Symptomatic secondary amyloidosis of the bladder is very rare. To date, only 15 cases have been reported in the American and European literatures. This seems to be the first case reported in Japan.

A patient with a huge pelvic fibromatosis, a form of intra-abdominal desmoid, encroaching on the urinary bladder is described. Because of its rarity, there is frequently a lack of diagnostic awareness of this tumor, particularly in the gynecological or urological patient. Although this tumor is a locally invasive benign tumor which dose not metastasize, management by radical tumor excision without the sacrifice of the major pelvic nerves and vessels is mandatory, since this tumor has generally a high postsurgical recurrence rate.