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7. The environmental monitoring system at the COSINE-100 experiment

Author

H. Kim, G. Adhikari, E. Barbosa de Souza, N. Carlin, J.J. Choi, S. Choi, M. Djamal, A.C. Ezeribe, L.E. França, C. Ha, I.S. Hahn, E.J. Jeon, J.H. Jo, H.W. Joo, W.G. Kang, M. Kauer, H.J. Kim, K.W. Kim, S.H. Kim, S.K. Kim, W.K. Kim, Y.D. Kim, Y.H. Kim, Y.J. Ko, E.K. Lee, H. Lee, H.S. Lee, H.Y. Lee, I.S. Lee, J. Lee, J.Y. Lee, M.H. Lee, S.H. Lee, S.M. Lee, D.S. Leonard, B.B. Manzato, R.H. Maruyama, R.J. Neal, S.L. Olsen, B.J. Park, H.K. Park, H.S. Park, K.S. Park, R.L.C. Pitta, H. Prihtiadi, S.J. Ra, C. Rott, K.A. Shin, A. Scarff, N.J.C. Spooner, W.G. Thompson, L. Yang, and G.H. Yu

Subjects
High Energy Physics - Experiment (hep-ex), Physics - Instrumentation and Detectors, FOS: Physical sciences, Instrumentation and Detectors (physics.ins-det), Instrumentation, Mathematical Physics, High Energy Physics - Experiment
Abstract

The COSINE-100 experiment is designed to test the DAMA experiment which claimed an observation of a dark matter signal from an annual modulation in their residual event rate. To measure the 1 %-level signal amplitude, it is crucial to control and monitor nearly all environmental quantities that might systematically mimic the signal. The environmental monitoring also helps ensure a stable operation of the experiment. Here, we describe the design and performance of the centralized environmental monitoring system for the COSINE-100 experiment., 13 pages, 11 figures

Published
2021

9. Validation of Freezing-of-Gait Monitoring Using Smartphone

Author

Won-Jin Yi, Beomseok Jeon, Hong Ji Lee, Han Byul Kim, Hye Young Park, Woong-Woo Lee, Hyo Seon Jeon, Sang Kyong Kim, Chae Won Shin, and K.S. Park

Subjects
medicine.medical_specialty, Parkinson's disease, genetic structures, 0206 medical engineering, Health Informatics, 02 engineering and technology, Motor symptoms, 03 medical and health sciences, 0302 clinical medicine, Gait (human), Physical medicine and rehabilitation, Health Information Management, Accelerometry, Image Processing, Computer-Assisted, Humans, Medicine, Gait, Gait Disorders, Neurologic, business.industry, Parkinson Disease, General Medicine, medicine.disease, 020601 biomedical engineering, Telemedicine, Smartphone, business, Algorithms, 030217 neurology & neurosurgery
Abstract

Freezing of gait (FOG) is a commonly observed motor symptom for patients with Parkinson's disease (PD). The symptoms of FOG include reduced step lengths or motor blocks, even with an evident intention of walking. FOG should be monitored carefully because it not only lowers the patient's quality of life, but also significantly increases the risk of injury.In previous studies, patients had to wear several sensors on the body and another computing device was needed to run the FOG detection algorithm. Moreover, the features used in the algorithm were based on low-level and hand-crafted features. In this study, we propose a FOG detection system based on a smartphone, which can be placed in the patient's daily wear, with a novel convolutional neural network (CNN).The walking data of 32 PD patients were collected from the accelerometer and gyroscope embedded in the smartphone, located in the trouser pocket. The motion signals measured by the sensors were converted into the frequency domain and stacked into a 2D image for the CNN input. A specialized CNN model for FOG detection was determined through a validation process.We compared our performances with the results acquired by the previously reported settings. The proposed architecture discriminated the freezing events from the normal activities with an average sensitivity of 93.8% and a specificity of 90.1%.Using our methodology, the precise and continuous monitoring of freezing events with unconstrained sensing can assist patients in managing their chronic disease in daily life effectively.

Published
2018
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10. A simplified method to predict fatigue damage of offshore riser subjected to vortex-induced vibration by adopting current index concept

Author

H.S. Choi, Su Young Yu, Do Kyun Kim, E. W. C. Wong, Atilla Incecik, and K.S. Park

Subjects
Environmental Engineering, Index (economics), Current load, Computer simulation, business.industry, 020101 civil engineering, Ocean Engineering, Fatigue damage, 02 engineering and technology, Structural engineering, 01 natural sciences, 010305 fluids & plasmas, 0201 civil engineering, Vibration, Vortex-induced vibration, 0103 physical sciences, Environmental science, Submarine pipeline, Current (fluid), business
Abstract

In the present study, an innovative method for estimating fatigue performance of risers under vortex-induced vibration (VIV) is proposed. Generally, fatigue performance is affected by the surrounding environment such as wind, wave, and current. It is well known that current is the most influential load among all for offshore risers. In structural safety aspect, strength and fatigue are the most important factors for riser design. In addition, fatigue design is affinitive to the VIV phenomenon. For the analysis of fatigue performance of riser, SHEAR7 numerical simulation code which is commonly used in offshore industry is applied. In order to identify the relation between current load and fatigue performance of riser, Fatigue damage versus Current index (F-C) diagram has been proposed. F-C diagram may cover change of current profiles and help predict the fatigue damage under VIV. In case of current profile, a total of sixty cases of current scenarios are considered based on six representative sea-states. The obtained results from this study will be a useful guideline to predict the effect of current on the fatigue performance of riser.

Published
2018
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11. An empirical formulation for predicting the ultimate strength of stiffened panels subjected to longitudinal compression

Author

Do Kyun Kim, Mungyung Kim, O.J. Hwang, K.S. Park, and Hui Ling Lim

Subjects
Engineering, Environmental Engineering, business.industry, 020101 civil engineering, Ocean Engineering, 02 engineering and technology, Function (mathematics), Structural engineering, Span (engineering), Compression (physics), Nonlinear finite element analysis, 01 natural sciences, 010305 fluids & plasmas, 0201 civil engineering, Residual strength, Buckling, 0103 physical sciences, Ultimate tensile strength, Empirical formula, business
Abstract

There are several methods such as experimental, numerical, and analytical methods which are the mostly adopted in the verification of proposed design code or guidelines to calculate the ultimate strength performance of stiffened panel structures. This study proposes an advanced empirical formula shape, which is a function of plate slenderness ratio and column slenderness ratio with two (2) correction coefficients ( C 1 and C 2 ), used to predict the ultimate strength performance of stiffened panel structures in ships. In addition, the two aforementioned correction coefficients were decided and verified by obtaining the result of an ANSYS nonlinear finite element analysis. An average level of initial imperfection and 2 bay – 2 span (1/2 – 1 – 1/2) model were adopted in the proposed empirical formula. The effects of residual strength were not considered in this study. A total of 124 stiffened panels with four different plate slenderness ratios ( β ) and changing column slenderness ratio (λ) were selected for the simulation scenarios. To confirm the accuracy of the obtained formula, a statistical analysis was also conducted on the ANSYS results and other existing formulas. The proposed method and its details were documented.

Published
2017
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12. Differential protein stability and clinical responses ofEML4-ALK fusion variants to various ALK inhibitors in advancedALK-rearranged non-small cell lung cancer

Author

K.S. Park, C.G. Woo, Sun Whe Kim, Mark W. Richards, J.Y. Song, Richard Bayliss, S.J. Jang, Jene Choi, B. Lee, D.H. Lee, and S. Seo

Subjects
Male, 0301 basic medicine, Alectinib, Lung Neoplasms, Oncogene Proteins, Fusion, Pyridines, Kaplan-Meier Estimate, Bioinformatics, 0302 clinical medicine, Piperidines, Carcinoma, Non-Small-Cell Lung, hemic and lymphatic diseases, Genotype, Anaplastic lymphoma kinase, Sulfones, In Situ Hybridization, Fluorescence, Protein Stability, Hematology, Middle Aged, Oncology, 030220 oncology & carcinogenesis, Female, medicine.drug, Adult, medicine.drug_class, Carbazoles, Antineoplastic Agents, Disease-Free Survival, Article, 03 medical and health sciences, Crizotinib, medicine, Humans, Progression-free survival, Lung cancer, Protein Kinase Inhibitors, Aged, Retrospective Studies, Ceritinib, business.industry, medicine.disease, ALK inhibitor, Pyrimidines, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer research, Pyrazoles, business, Multiplex Polymerase Chain Reaction
Abstract

Background Anaplastic lymphoma kinase (ALK) inhibition using crizotinib has become the standard of care in advancedALK-rearranged non-small cell lung cancer (NSCLC), but the treatment outcomes and duration of response vary widely. Echinoderm microtubule-associated protein-like 4 (EML4)-ALK is the most common translocation, and the fusion variants show different sensitivity to crizotinibin vitro. However, there are only limited data on the specificEML4-ALK variants and clinical responses of patients to various ALK inhibitors. Patients and methods By multiplex reverse-transcriptase PCR, which detects 12 variants of knownEML4-ALK rearrangements, we retrospectively determinedALK fusion variants in 54 advancedALK rearrangement-positive NSCLCs. We subdivided the patients into two groups (variants 1/2/others and variants 3a/b) by protein stability and evaluated correlations of the variant status with clinical responses to crizotinib, alectinib, or ceritinib. Moreover, we established the EML4-ALK variant-expressing system and analyzed patterns of sensitivity of the variants to ALK inhibitors. Results Of the 54 tumors analyzed,EML4-ALK variants 3a/b (44.4%) was the most common type, followed by variants 1 (33.3%) and 2 (11.1%). The 2-year progression-free survival (PFS) rate was 76.0% [95% confidence interval (CI) 56.8–100] in groupEML4-ALK variants 1/2/others versus 26.4% (95% CI 10.5–66.6) in group variants 3a/b (P = 0.034) among crizotinib-treated patients. Meanwhile, the 2-year PFS rate was 69.0% (95% CI 49.9–95.4) in group variants 1/2/others versus 32.7% (95% CI 15.6–68.4) in group variants 3a/b (P = 0.108) among all crizotinib-, alectinib-, and ceritinib-treated patients. Variant 3a- or 5a-harboring cells were resistant to ALK inhibitors with >10-fold higher half maximal inhibitory concentrationin vitro. Conclusion Our findings show that groupEML4-ALK variants 3a/b may be a major source of ALK inhibitor resistance in the clinic. The variant-specific genotype of theEML4-ALK fusion allows for more precise stratification of patients with advanced NSCLC.

Published
2017
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14. The Role of Consolidative Radiotherapy after Complete Remission to R-CHOP Immunochemotherapy in Stage III-IV Diffuse Large B-Cell Lymphoma: A Single Institutional Experience

Author

J.H. Hong, Y.W. Jeon, S.E. Jung, K.S. Park, J.H. O, H.H. Lee, S.G. Cho, and B.O. Choi

Subjects
Oncology, Cancer Research, medicine.medical_specialty, Radiation, business.industry, medicine.medical_treatment, Complete remission, medicine.disease, Radiation therapy, Internal medicine, medicine, Radiology, Nuclear Medicine and imaging, Stage (cooking), business, Diffuse large B-cell lymphoma
Published
2019
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17. Factors influencing Korean nurses’ attitudes towards hospice care

Author

K.S. Park and H.A. Yeom

Subjects
medicine.medical_specialty, Palliative care, business.industry, Work experience, Unit (housing), Nursing, Scale (social sciences), Family medicine, medicine, Descriptive research, business, End-of-life care, General Nursing, Hospice care, Health policy
Abstract

Background While the need for hospice care is increasing in Korea, there is limited research describing the way hospice care is understood by hospital ward nurses who may have relatively limited opportunities for hospice education in their workplace. Aim This study aimed to describe Korean nurses’ attitudes towards hospice care and to examine the relationships between nurses’ attitudes towards hospice care and their demographic and work-related characteristics. Methods This was a cross-sectional descriptive study. A total of 348 registered nurses recruited from six general hospitals were surveyed using a structured questionnaire. Measurements included general and work-related characteristics and the Frommelt Attitude Toward Care of the Dying Scale. Results The mean score for nurses’ attitudes towards hospice care was 2.52 out of a maximum of 3.0. More positive attitudes towards hospice care were associated with older age, married status, a higher level of education, working at a hospice unit, a higher job position, more years of work experience, having previous experience caring for dying patients and having received education in hospice care. Factors predicting nurses’ attitudes towards hospice care included the number of years of work experience and working at a hospice unit in a hospital, with an explanatory power of 22%. Limitations The study was conducted in tertiary care hospitals in Seoul metropolitan area; results may therefore differ in other geographical regions. Conclusion Education on hospice care should be targeted to less experienced, younger staff nurses who have no previous education on hospice care or have not worked in a hospice unit. Implication for Nursing and Health Policy Tertiary hospitals need to provide more opportunities for their nurses to obtain continuing education on hospice care or increase the number of courses available at the institutional level in order to enhance their nurses’ attitudes towards hospice care.

Published
2014
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20. Development of Multiple Slim Type Damper System and Performance Test

Author

D.H. Park, D. Kim, E.H. Sung, K.S. Park, H.J. Cho, and J.H. Park

Subjects
Engineering, Scale (ratio), business.industry, Vibration control, Linkage (mechanical), Structural engineering, Type (model theory), Damper, law.invention, Damping capacity, Dynamic loading, Control theory, law, Damping torque, business
Abstract

For the vibration control of residential buildings, a multiple type slim damper system is developed and dynamic performance test is performed in this study. In conventional damping systems, larger installation space is required in order to achieve acceptable seismic performance, and as a result, it is difficult to determine efficient damping capacity of the device. The proposed damping device is composed of several small slim type dampers and linkage units. It can control damping capacity easily by changing the number of the small damper. To evaluate the proposed damping device, three slim type dampers (single-type, triple-type and penta-type) are designed and manufactured in real scale. Dynamic loading tests are performed by using the three manufactured dampers. From the tests, it is shown that damping coefficient is proportional to the number of the damper combined. Thus, test results validates the practicality of the proposed slim type dampers. applying nonlinear curve fitting technique, numerical model of the dampers are developed and presented.

Published
2014
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23. THE RISK OF MORTALITY AND CARDIOVASCULAR DISEASE IS INCREASED IN FIREFIGHTERS WITH ELEVATED BLOOD PRESSURE COMPARED TO THE GENERAL POPULATION

Author

C. Kim, C.J. Lee, K.S. Park, N. Nor, S. Park, and S.-J. Chang

Subjects
education.field_of_study, medicine.medical_specialty, Physiology, business.industry, Population, Disease, 030204 cardiovascular system & hematology, Affect (psychology), Elevated blood, 03 medical and health sciences, 0302 clinical medicine, Increased risk, Blood pressure, Emergency medicine, Internal Medicine, Risk of mortality, Medicine, 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, business, education
Abstract

Objective:Firefighters are known to have increased risk of cardiovascular disease when on duty. However, there are no studies that investigated how blood pressure levels affect the cardiovascular risk of firefighters when compared to age-gender matched control.Design and method:This retrospective co

Published
2019
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25. EFFECT OF BORDEAUX MIXTURE SPRAY ON FRUIT QUALITY OF 'KYOHO' GRAPE AND COPPER ACCUMULATION IN THE SOIL

Author

T.J. Lim, K.S. Park, S.M. Jung, Y.Y. Huh, J.H. Roh, and J.C. Nam

Subjects
Horticulture, Agronomy, biology, Chemistry, Bordeaux mixture, Plasmopara viticola, Soil water, Downy mildew, chemistry.chemical_element, Copper levels, biology.organism_classification, Copper
Abstract

In 2008, residual copper contents in soils of Korean vineyards under different Bordeaux mixture spray programs were determined. In all 25 vineyards tested, copper contents in the soil were below the 50 mg kg-1 soil maximum contamination standard. However, as the number of sprays increased, the residual copper content also increased. The effects of Bordeaux mixture on ‘Kyoho’ grape quality and incidence of downy mildew were also investigated. Grape quality was improved in many Bordeaux mixture treated blocks because most leaves were not infected with downy mildew (Plasmopara viticola). The effect of bagging ‘Kyoho’ grape bunches before spraying with Bordeaux mixture was also determined. Grape bunches without paper bags had poor appearance, which reduces the market price, and elevated copper levels in the grape juice. Copper concentration in the naked bunches sprayed with Bordeaux mixture was close to the maximum limit of 20 mg kg-1 fruit for table grapes.

Published
2013
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26. Measurement of the mass difference between top quark and antiquark in pp collisions at s=8 TeV

Author

Chatrchyan, S. Khachatryan, V. Sirunyan, A.M. Tumasyan, A. Adam, W. Bergauer, T. Dragicevic, M. Erö, J. Fabjan, C. Friedl, M. Frühwirth, R. Ghete, V.M. Hartl, C. Hörmann, N. Hrubec, J. Jeitler, M. Kiesenhofer, W. Knünz, V. Krammer, M. Krätschmer, I. Liko, D. Mikulec, I. Rabady, D. Rahbaran, B. Rohringer, H. Schöfbeck, R. Strauss, J. Taurok, A. Treberer-Treberspurg, W. Waltenberger, W. Wulz, C.-E. Mossolov, V. Shumeiko, N. Suarez Gonzalez, J. Alderweireldt, S. Bansal, M. Bansal, S. Cornelis, T. De Wolf, E.A. Janssen, X. Knutsson, A. Luyckx, S. Mucibello, L. Ochesanu, S. Roland, B. Rougny, R. Van Haevermaet, H. Van Mechelen, P. Van Remortel, N. Van Spilbeeck, A. Blekman, F. Blyweert, S. D'Hondt, J. Heracleous, N. Kalogeropoulos, A. Keaveney, J. Kim, T.J. Lowette, S. Maes, M. Olbrechts, A. Strom, D. Tavernier, S. Van Doninck, W. Van Mulders, P. Van Onsem, G.P. Villella, I. Caillol, C. Clerbaux, B. De Lentdecker, G. Favart, L. Gay, A.P.R. Hreus, T. Léonard, A. Marage, P.E. Mohammadi, A. Perniè, L. Reis, T. Seva, T. Thomas, L. Vander Velde, C. Vanlaer, P. Wang, J. Adler, V. Beernaert, K. Benucci, L. Cimmino, A. Costantini, S. Dildick, S. Garcia, G. Klein, B. Lellouch, J. Mccartin, J. Ocampo Rios, A.A. Ryckbosch, D. Sigamani, M. Strobbe, N. Thyssen, F. Tytgat, M. Walsh, S. Yazgan, E. Zaganidis, N. Basegmez, S. Beluffi, C. Bruno, G. Castello, R. Caudron, A. Ceard, L. Da Silveira, G.G. Delaere, C. du Pree, T. Favart, D. Forthomme, L. Giammanco, A. Hollar, J. Jez, P. Komm, M. Lemaitre, V. Liao, J. Militaru, O. Nuttens, C. Pagano, D. Pin, A. Piotrzkowski, K. Popov, A. Quertenmont, L. Selvaggi, M. Vidal Marono, M. Vizan Garcia, J.M. Beliy, N. Caebergs, T. Daubie, E. Hammad, G.H. Alves, G.A. Correa Martins Junior, M. Dos Reis Martins, T. Pol, M.E. Souza, M.H.G. Aldá Júnior, W.L. Carvalho, W. Chinellato, J. Custódio, A. Da Costa, E.M. De Jesus Damiao, D. De Oliveira Martins, C. Fonseca De Souza, S. Malbouisson, H. Malek, M. Matos Figueiredo, D. Mundim, L. Nogima, H. Prado Da Silva, W.L. Santaolalla, J. Santoro, A. Sznajder, A. Tonelli Manganote, E.J. Vilela Pereira, A. Bernardes, C.A. Dias, F.A. Fernandez Perez Tomei, T.R. Gregores, E.M. Lagana, C. Mercadante, P.G. Novaes, S.F. Padula, S.S. Genchev, V. Iaydjiev, P. Marinov, A. Piperov, S. Rodozov, M. Sultanov, G. Vutova, M. Dimitrov, A. Glushkov, I. Hadjiiska, R. Kozhuharov, V. Litov, L. Pavlov, B. Petkov, P. Bian, J.G. Chen, G.M. Chen, H.S. Chen, M. Du, R. Jiang, C.H. Liang, D. Liang, S. Meng, X. Plestina, R. Tao, J. Wang, X. Wang, Z. Asawatangtrakuldee, C. Ban, Y. Guo, Y. Li, Q. Li, W. Liu, S. Mao, Y. Qian, S.J. Wang, D. Zhang, L. Zou, W. Avila, C. Carrillo Montoya, C.A. Chaparro Sierra, L.F. Florez, C. Gomez, J.P. Gomez Moreno, B. Sanabria, J.C. Godinovic, N. Lelas, D. Polic, D. Puljak, I. Antunovic, Z. Kovac, M. Brigljevic, V. Kadija, K. Luetic, J. Mekterovic, D. Morovic, S. Sudic, L. Attikis, A. Mavromanolakis, G. Mousa, J. Nicolaou, C. Ptochos, F. Razis, P.A. Finger, M. Finger, M., Jr. El-khateeb, E. Elkafrawy, T. Mahmoud, M.A. Mohamed, A. Radi, A. Salama, E. Kadastik, M. Müntel, M. Murumaa, M. Raidal, M. Rebane, L. Tiko, A. Eerola, P. Fedi, G. Voutilainen, M. Härkönen, J. Karimäki, V. Kinnunen, R. Kortelainen, M.J. Lampén, T. Lassila-Perini, K. Lehti, S. Lindén, T. Luukka, P. Mäenpää, T. Peltola, T. Tuominen, E. Tuominiemi, J. Tuovinen, E. Wendland, L. Tuuva, T. Besancon, M. Couderc, F. Dejardin, M. Denegri, D. Fabbro, B. Faure, J.L. Ferri, F. Ganjour, S. Givernaud, A. Gras, P. Hamel de Monchenault, G. Jarry, P. Locci, E. Malcles, J. Nayak, A. Rander, J. Rosowsky, A. Titov, M. Baffioni, S. Beaudette, F. Busson, P. Charlot, C. Daci, N. Dahms, T. Dalchenko, M. Dobrzynski, L. Florent, A. Granier de Cassagnac, R. Haguenauer, M. Miné, P. Mironov, C. Naranjo, I.N. Nguyen, M. Ochando, C. Paganini, P. Sabes, D. Salerno, R. Sirois, Y. Veelken, C. Yilmaz, Y. Zabi, A. Agram, J.-L. Andrea, J. Bloch, D. Brom, J.-M. Chabert, E.C. Collard, C. Conte, E. Drouhin, F. Fontaine, J.-C. Gelé, D. Goerlach, U. Goetzmann, C. Juillot, P. Le Bihan, A.-C. Van Hove, P. Gadrat, S. Beauceron, S. Beaupere, N. Boudoul, G. Brochet, S. Chasserat, J. Chierici, R. Contardo, D. Depasse, P. El Mamouni, H. Fan, J. Fay, J. Gascon, S. Gouzevitch, M. Ille, B. Kurca, T. Lethuillier, M. Mirabito, L. Perries, S. Ruiz Alvarez, J.D. Sgandurra, L. Sordini, V. Vander Donckt, M. Verdier, P. Viret, S. Xiao, H. Tsamalaidze, Z. Autermann, C. Beranek, S. Bontenackels, M. Calpas, B. Edelhoff, M. Feld, L. Hindrichs, O. Klein, K. Ostapchuk, A. Perieanu, A. Raupach, F. Sammet, J. Schael, S. Sprenger, D. Weber, H. Wittmer, B. Zhukov, V. Ata, M. Caudron, J. Dietz-Laursonn, E. Duchardt, D. Erdmann, M. Fischer, R. Güth, A. Hebbeker, T. Heidemann, C. Hoepfner, K. Klingebiel, D. Knutzen, S. Kreuzer, P. Merschmeyer, M. Meyer, A. Olschewski, M. Padeken, K. Papacz, P. Reithler, H. Schmitz, S.A. Sonnenschein, L. Teyssier, D. Thüer, S. Weber, M. Cherepanov, V. Erdogan, Y. Flügge, G. Geenen, H. Geisler, M. Haj Ahmad, W. Hoehle, F. Kargoll, B. Kress, T. Kuessel, Y. Lingemann, J. Nowack, A. Nugent, I.M. Perchalla, L. Pooth, O. Stahl, A. Asin, I. Bartosik, N. Behr, J. Behrenhoff, W. Behrens, U. Bell, A.J. Bergholz, M. Bethani, A. Borras, K. Burgmeier, A. Cakir, A. Calligaris, L. Campbell, A. Choudhury, S. Costanza, F. Diez Pardos, C. Dooling, S. Dorland, T. Eckerlin, G. Eckstein, D. Eichhorn, T. Flucke, G. Geiser, A. Grebenyuk, A. Gunnellini, P. Habib, S. Hauk, J. Hempel, M. Horton, D. Jung, H. Kasemann, M. Katsas, P. Kleinwort, C. Krämer, M. Krücker, D. Lange, W. Leonard, J. Lipka, K. Lohmann, W. Lutz, B. Mankel, R. Marfin, I. Melzer-Pellmann, I.-A. Meyer, A.B. Mittag, G. Mnich, J. Mussgiller, A. Naumann-Emme, S. Novgorodova, O. Nowak, F. Perrey, H. Petrukhin, A. Pitzl, D. Placakyte, R. Raspereza, A. Ribeiro Cipriano, P.M. Riedl, C. Ron, E. Sahin, M.Ö. Salfeld-Nebgen, J. Schmidt, R. Schoerner-Sadenius, T. Schröder, M. Stein, M. Vargas Trevino, A.D.R. Walsh, R. Wissing, C. Aldaya Martin, M. Blobel, V. Enderle, H. Erfle, J. Garutti, E. Goebel, K. Görner, M. Gosselink, M. Haller, J. Höing, R.S. Kirschenmann, H. Klanner, R. Kogler, R. Lange, J. Marchesini, I. Ott, J. Peiffer, T. Pietsch, N. Poehlsen, J. Rathjens, D. Sander, C. Schettler, H. Schleper, P. Schlieckau, E. Schmidt, A. Seidel, M. Sola, V. Stadie, H. Steinbrück, G. Troendle, D. Usai, E. Vanelderen, L. Barth, C. Baus, C. Berger, J. Böser, C. Butz, E. Chwalek, T. De Boer, W. Descroix, A. Dierlamm, A. Feindt, M. Guthoff, M. Hartmann, F. Hauth, T. Held, H. Hoffmann, K.H. Husemann, U. Katkov, I. Kornmayer, A. Kuznetsova, E. Lobelle Pardo, P. Martschei, D. Mozer, M.U. Müller, T. Niegel, M. Nürnberg, A. Oberst, O. Quast, G. Rabbertz, K. Ratnikov, F. Röcker, S. Schilling, F.-P. Schott, G. Simonis, H.J. Stober, F.M. Ulrich, R. Wagner-Kuhr, J. Wayand, S. Weiler, T. Wolf, R. Zeise, M. Anagnostou, G. Daskalakis, G. Geralis, T. Kesisoglou, S. Kyriakis, A. Loukas, D. Markou, A. Markou, C. Ntomari, E. 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Tadel, M. Tu, Y. Vartak, A. Wasserbaech, S. Würthwein, F. Yagil, A. Yoo, J. Barge, D. Campagnari, C. Danielson, T. Flowers, K. Geffert, P. George, C. Golf, F. Incandela, J. Justus, C. Magaña Villalba, R. Mccoll, N. Pavlunin, V. Richman, J. Rossin, R. Stuart, D. To, W. West, C. Apresyan, A. Bornheim, A. Bunn, J. Chen, Y. Di Marco, E. Duarte, J. Kcira, D. Mott, A. Newman, H.B. Pena, C. Rogan, C. Spiropulu, M. Timciuc, V. Wilkinson, R. Xie, S. Zhu, R.Y. Azzolini, V. Calamba, A. Carroll, R. Ferguson, T. Iiyama, Y. Jang, D.W. Paulini, M. Russ, J. Vogel, H. Vorobiev, I. Cumalat, J.P. Drell, B.R. Ford, W.T. Gaz, A. Luiggi Lopez, E. Nauenberg, U. Smith, J.G. Stenson, K. Ulmer, K.A. Wagner, S.R. Alexander, J. Chatterjee, A. Eggert, N. Gibbons, L.K. Hopkins, W. Khukhunaishvili, A. Kreis, B. Mirman, N. Nicolas Kaufman, G. Patterson, J.R. Ryd, A. Salvati, E. Sun, W. Teo, W.D. Thom, J. Thompson, J. Tucker, J. Weng, Y. Winstrom, L. Wittich, P. Winn, D. Abdullin, S. Albrow, M. Anderson, J. Apollinari, G. Bauerdick, L.A.T. Beretvas, A. Berryhill, J. Bhat, P.C. Burkett, K. Butler, J.N. Chetluru, V. Cheung, H.W.K. Chlebana, F. Cihangir, S. Elvira, V.D. Fisk, I. Freeman, J. Gao, Y. Gottschalk, E. Gray, L. Green, D. Gutsche, O. Hare, D. Harris, R.M. Hirschauer, J. Hooberman, B. Jindariani, S. Johnson, M. Joshi, U. Kaadze, K. Klima, B. Kwan, S. Linacre, J. Lincoln, D. Lipton, R. Lykken, J. Maeshima, K. Marraffino, J.M. Martinez Outschoorn, V.I. Maruyama, S. Mason, D. McBride, P. Mishra, K. Mrenna, S. Musienko, Y. Nahn, S. Newman-Holmes, C. O'Dell, V. Prokofyev, O. Ratnikova, N. Sexton-Kennedy, E. Sharma, S. Spalding, W.J. Spiegel, L. Taylor, L. Tkaczyk, S. Tran, N.V. Uplegger, L. Vaandering, E.W. Vidal, R. Whitmore, J. Wu, W. Yang, F. Yun, J.C. Acosta, D. Avery, P. Bourilkov, D. Cheng, T. Das, S. De Gruttola, M. Di Giovanni, G.P. Dobur, D. Field, R.D. Fisher, M. Fu, Y. Furic, I.K. Hugon, J. Kim, B. Konigsberg, J. Korytov, A. Kropivnitskaya, A. Kypreos, T. Low, J.F. Matchev, K. Milenovic, P. Mitselmakher, G. Muniz, L. Rinkevicius, A. Shchutska, L. Skhirtladze, N. Snowball, M. Yelton, J. Zakaria, M. Gaultney, V. Hewamanage, S. Linn, S. Markowitz, P. Martinez, G. Rodriguez, J.L. Adams, T. Askew, A. Bochenek, J. Chen, J. Diamond, B. Haas, J. Hagopian, S. Hagopian, V. Johnson, K.F. Prosper, H. Veeraraghavan, V. Weinberg, M. Baarmand, M.M. Dorney, B. Hohlmann, M. Kalakhety, H. Yumiceva, F. Adams, M.R. Apanasevich, L. Bazterra, V.E. Betts, R.R. Bucinskaite, I. Cavanaugh, R. Evdokimov, O. Gauthier, L. Gerber, C.E. Hofman, D.J. Khalatyan, S. Kurt, P. Moon, D.H. O'Brien, C. Silkworth, C. Turner, P. Varelas, N. Akgun, U. Albayrak, E.A. Bilki, B. Clarida, W. Dilsiz, K. Duru, F. Merlo, J.-P. Mermerkaya, H. Mestvirishvili, A. Moeller, A. Nachtman, J. Ogul, H. Onel, Y. Ozok, F. Sen, S. Tan, P. Tiras, E. Wetzel, J. Yetkin, T. Yi, K. Barnett, B.A. Blumenfeld, B. Bolognesi, S. Fehling, D. Gritsan, A.V. Maksimovic, P. Martin, C. Swartz, M. Whitbeck, A. Baringer, P. Bean, A. Benelli, G. Kenny III, R.P. Murray, M. Noonan, D. Sanders, S. Sekaric, J. Stringer, R. Wang, Q. Wood, J.S. Barfuss, A.F. Chakaberia, I. Ivanov, A. Khalil, S. Makouski, M. Maravin, Y. Saini, L.K. Shrestha, S. Svintradze, I. Gronberg, J. Lange, D. Rebassoo, F. Wright, D. Baden, A. Calvert, B. Eno, S.C. Gomez, J.A. Hadley, N.J. Kellogg, R.G. Kolberg, T. Lu, Y. Marionneau, M. Mignerey, A.C. Pedro, K. Skuja, A. Temple, J. Tonjes, M.B. Tonwar, S.C. Apyan, A. Barbieri, R. Bauer, G. Busza, W. Cali, I.A. Chan, M. Di Matteo, L. Dutta, V. Gomez Ceballos, G. Goncharov, M. Gulhan, D. Klute, M. Lai, Y.S. Lee, Y.-J. Levin, A. Luckey, P.D. Ma, T. Paus, C. Ralph, D. Roland, C. Roland, G. Stephans, G.S.F. Stöckli, F. Sumorok, K. Velicanu, D. Veverka, J. Wyslouch, B. Yang, M. Yoon, A.S. Zanetti, M. Zhukova, V. Dahmes, B. De Benedetti, A. Gude, A. Kao, S.C. Klapoetke, K. Kubota, Y. Mans, J. Pastika, N. Rusack, R. Singovsky, A. Tambe, N. Turkewitz, J. Acosta, J.G. Cremaldi, L.M. Kroeger, R. Oliveros, S. Perera, L. Rahmat, R. Sanders, D.A. Summers, D. Avdeeva, E. Bloom, K. Bose, S. Claes, D.R. Dominguez, A. Gonzalez Suarez, R. Keller, J. Kravchenko, I. Lazo-Flores, J. Malik, S. Meier, F. Snow, G.R. Dolen, J. Godshalk, A. Iashvili, I. Jain, S. Kharchilava, A. Kumar, A. Rappoccio, S. Wan, Z. Alverson, G. Barberis, E. Baumgartel, D. Chasco, M. Haley, J. Massironi, A. Nash, D. Orimoto, T. Trocino, D. Wood, D. Zhang, J. Anastassov, A. Hahn, K.A. Kubik, A. Lusito, L. Mucia, N. Odell, N. Pollack, B. Pozdnyakov, A. Schmitt, M. Stoynev, S. Sung, K. Velasco, M. Won, S. Berry, D. Brinkerhoff, A. Chan, K.M. Drozdetskiy, A. Hildreth, M. Jessop, C. Karmgard, D.J. Kolb, J. Lannon, K. Luo, W. Lynch, S. Marinelli, N. Morse, D.M. Pearson, T. Planer, M. Ruchti, R. Slaunwhite, J. Valls, N. Wayne, M. Wolf, M. Antonelli, L. Bylsma, B. Durkin, L.S. Flowers, S. Hill, C. Hughes, R. Kotov, K. Ling, T.Y. Puigh, D. Rodenburg, M. Smith, G. Vuosalo, C. Winer, B.L. Wolfe, H. Wulsin, H.W. Berry, E. Elmer, P. Halyo, V. Hebda, P. Hegeman, J. Hunt, A. Jindal, P. Koay, S.A. Lujan, P. Marlow, D. Medvedeva, T. Mooney, M. Olsen, J. Piroué, P. Quan, X. Raval, A. Saka, H. Stickland, D. Tully, C. Werner, J.S. Zenz, S.C. Zuranski, A. Brownson, E. Lopez, A. Mendez, H. Ramirez Vargas, J.E. Alagoz, E. Benedetti, D. Bolla, G. Bortoletto, D. De Mattia, M. Everett, A. Hu, Z. Jones, M. Jung, K. Kress, M. Leonardo, N. Lopes Pegna, D. Maroussov, V. Merkel, P. Miller, D.H. Neumeister, N. Radburn-Smith, B.C. Shipsey, I. Silvers, D. Svyatkovskiy, A. Wang, F. Xie, W. Xu, L. Yoo, H.D. Zablocki, J. Zheng, Y. Parashar, N. Adair, A. Akgun, B. Ecklund, K.M. Geurts, F.J.M. Li, W. Michlin, B. Padley, B.P. Redjimi, R. Roberts, J. Zabel, J. Betchart, B. Bodek, A. Covarelli, R. de Barbaro, P. Demina, R. Eshaq, Y. Ferbel, T. Garcia-Bellido, A. Goldenzweig, P. Han, J. Harel, A. Miner, D.C. Petrillo, G. Vishnevskiy, D. Zielinski, M. Bhatti, A. Ciesielski, R. Demortier, L. Goulianos, K. Lungu, G. Malik, S. Mesropian, C. Arora, S. Barker, A. Chou, J.P. Contreras-Campana, C. Contreras-Campana, E. Duggan, D. Ferencek, D. Gershtein, Y. Gray, R. Halkiadakis, E. Hidas, D. Lath, A. Panwalkar, S. Park, M. Patel, R. Rekovic, V. Robles, J. Salur, S. Schnetzer, S. Seitz, C. Somalwar, S. Stone, R. Thomas, S. Thomassen, P. Walker, M. Rose, K. Spanier, S. Yang, Z.C. York, A. Bouhali, O. Eusebi, R. Flanagan, W. Gilmore, J. Kamon, T. Khotilovich, V. Krutelyov, V. Montalvo, R. Osipenkov, I. Pakhotin, Y. Perloff, A. Roe, J. Safonov, A. Sakuma, T. Suarez, I. Tatarinov, A. Toback, D. Akchurin, N. Cowden, C. Damgov, J. Dragoiu, C. Dudero, P.R. Kovitanggoon, K. Kunori, S. Lee, S.W. Libeiro, T. Volobouev, I. Appelt, E. Delannoy, A.G. Greene, S. Gurrola, A. Johns, W. Maguire, C. Mao, Y. Melo, A. Sharma, M. Sheldon, P. Snook, B. Tuo, S. Velkovska, J. Arenton, M.W. Boutle, S. Cox, B. Francis, B. Goodell, J. Hirosky, R. Ledovskoy, A. Lin, C. Neu, C. Wood, J. Gollapinni, S. Harr, R. Karchin, P.E. Kottachchi Kankanamge Don, C. Lamichhane, P. Sakharov, A. Belknap, D.A. Borrello, L. Carlsmith, D. Cepeda, M. Dasu, S. Duric, S. Friis, E. Grothe, M. Hall-Wilton, R. Herndon, M. Hervé, A. Klabbers, P. Klukas, J. Lanaro, A. Loveless, R. Mohapatra, A. Ojalvo, I. Perry, T. Pierro, G.A. Polese, G. Ross, I. Sarangi, T. Savin, A. Smith, W.H. Aziz, T. Banerjee, S. Chatterjee, R.M. Dugad, S. Ganguly, S. Ghosh, S. Guchait, M. Gurtu, A. Kole, G. Kumar, S. Maity, M. Majumder, G. Mazumdar, K. Mohanty, G.B. Parida, B. Sudhakar, K. Wickramage, N.

Subjects
High Energy Physics::Experiment
Abstract

The invariance of the standard model (SM) under the CPT transformation predicts equality of particle and antiparticle masses. This prediction is tested by measuring the mass difference between the top quark and antiquark (Δmt=mt−mt‾) that are produced in pp collisions at a center-of-mass energy of 8 TeV, using events with a muon or an electron and at least four jets in the final state. The analysis is based on data corresponding to an integrated luminosity of 19.6 fb−1collected by the CMS experiment at the LHC, and yields a value of Δmt=−0.15±0.19(stat)±0.09(syst) GeV, which is consistent with the SM expectation. This result is significantly more precise than previously reported measurements. © 2017 The Author(s)

Published
2017

28. <Field action report> Development and Application of Participatory Action Oriented Training(PAOT) for Improvement of Agricultural Working Environment in Korea

Author

J.S. Kim, K.H. Woo, Y.S. Min, B.K. Kim, K.S. Choi, and K.S. Park

Subjects
Engineering, Schedule (workplace), Medical education, Work (electrical), business.industry, Agriculture, Brainstorming, Questionnaire, Citizen journalism, Operations management, business, Occupational safety and health, Checklist
Abstract

Objectives: This study was conducted to develop a Korean version of the Participatory Action Oriented Training (PAOT) program and training materials for improvement of agricultural working environments. Methods: The PAOT manual and checklist were developed on the basis of the original English version of the training materials, a questionnaire survey of agricultural health and safety professionals, and a brainstorming conference. Good example pictures were collected through visits to agricultural workers' houses, and an easily understandable picture was drawn by an animation specialist. A PAOT action manual and five types of action checklists were developed for use in different agricultural environments. Each action checklist contained six categories and 38 items of agricultural health and safety principles; the six categories were material storage and handling, work stations and tools, machine safety, physical environment, working schedule and organization, and basic health and safety management. Incorporating these training materials, a one-day Korean PAOT program was developed. Results: Among 307 candidate agricultural workers from four rural Korean villages, 94 workers (59 males, 35 females) participated in a PAOT from July 2007 to Oct 2008. The PAOT program was successful and the mean self-estimated satisfaction score of the participants was greater than 90%. Conclusions: A Korean PAOT program and training materials were successfully developed and applied to Korean agricultural workers. Although more studies are needed, it is expected that PAOT will greatly contribute to the improvement of agricultural working conditions and health and safety through the use of agricultural workers' self initiatives.

Published
2010
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29. Superconformal filling of 41nm trenches with Cu electroless deposition on Au-activated self-assembled monolayer

Author

K.S. Park, Sung-Goon Kang, Chong Seung Yoon, Jae Hong Kim, Won-Kyu Han, Hyeun Hwan An, Gil-Ho Hwang, Seok-Jun Hong, M.J. Lee, and G. Hong

Subjects
Materials science, Annealing (metallurgy), Nanoparticle, Self-assembled monolayer, Nanotechnology, Condensed Matter Physics, Silane, Catalysis, chemistry.chemical_compound, chemistry, Chemical engineering, Electrical resistivity and conductivity, Monolayer, Trench, General Materials Science
Abstract

In order to completely fill a 41 nm trench pattern with Cu using electroless deposition (ELD), we introduced a method of forming Au catalytic layer based on a self-assembled monolayer (SAM) of aminopropyltriethoxy silane molecules as a coupling agent. The nano-sized Au catalyst layer was deposited on Ta/SiO2/Si substrate through electrostatic interactions between the positively charged amine-SAM layer on the substrate and the negatively charged Au nanoparticles. The interspacing among Au nanoparticles was adjusted by controlling the pH in order to obtain a close-packed catalytic layer. The size of deposited Au nanoparticle catalyst was approximately 4 nm and uniform distribution was obtained at pH 6. After Au catalysts were formed on the amine-coated substrate at pH 6, the substrate soaked in electroless bath with polyethylene glycol as an inhibiting additive. Cross-section views showed that the Cu completely filled the pattern without voids or seams. The electrical resistivity of the electrolessly deposited Cu films with 41 nm thickness was determined to be 2.6 μΩ cm after the annealing process; a this resistivity is 1.4 times lower than recommended by the International Technology Roadmap for Semiconductors. Therefore, the SAM modified ELD is a promising method for filling a 41 nm trench pattern with Cu.

Published
2010
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30. Light radiation through a transparent cathode plate with single-walled carbon nanotube field emitters

Author

J.H. Sok, K.S. Park, Yongho Seo, S.H. Lee, C.S. Lee, Jeungchoon Goak, Naesung Lee, H.S. Lee, E.S. Jang, and J.H. Han

Subjects
Materials science, Liquid-crystal display, business.industry, General Physics and Astronomy, Surfaces and Interfaces, General Chemistry, Backlight, Condensed Matter Physics, Cathode, Surfaces, Coatings and Films, Anode, law.invention, Field electron emission, Optics, Thin-film transistor, law, Heat generation, Light emission, business
Abstract

In the conventional carbon nanotube backlight units (CNT-BLUs), light passes through the phosphor-coated anode glass plate, which thus faces closely the thin film transistor (TFT) backplate of a liquid crystal display panel. This configuration makes heat dissipation structurally difficult because light emission and heat generation occur simultaneously at the anode. We propose a novel configuration of a CNT-BLU where the cathode rather than the anode faces the TFT backplate by turning it upside down. In this design, light passes through the transparent cathode glass plate while heating occurs at the anode. We demonstrated a novel design of CNT-BLU by fabricating transparent single-walled CNT field emitters on the cathode and by coating a reflecting metal layer on the anode. This study hopefully provides a clue to solve the anode-heating problem which would be inevitably confronted for high-luminance and large-area CNT-BLUs.

Published
2010
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31. 446 Protective Effect of DA-9401 in Finasteride-Induced Apoptosis in Rat Testis: Inositol Requiring Kinase 1 and C-Jun N-Terminal Kinase Pathway

Author

Sung Won Lee, M.R. Chae, K.K. Karna, K.K. Soni, K.S. Park, Yu Seob Shin, Jong Kwan Park, S.K. Yang, Hye Kyung Kim, Bo Ram Choi, and Chul Young Kim

Subjects
Psychiatry and Mental health, chemistry.chemical_compound, Endocrinology, Reproductive Medicine, chemistry, Kinase, Apoptosis, Urology, Endocrinology, Diabetes and Metabolism, c-jun, Finasteride, Inositol, Molecular biology
Published
2018
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33. Complete filling of 41nm trench pattern using Cu seed layer deposited by SAM-modified electroless plating and electron-beam evaporation

Author

G. Hong, Sukjoon Hong, K.S. Park, Haoqun An, S.G. Kang, Jae Hong Kim, Gil-Ho Hwang, Chong Seung Yoon, M.J. Lee, and Won-Kyu Han

Subjects
Materials science, Fabrication, Metallurgy, General Physics and Astronomy, Surfaces and Interfaces, General Chemistry, Condensed Matter Physics, Electron beam physical vapor deposition, Evaporation (deposition), Surfaces, Coatings and Films, Electrical resistivity and conductivity, Trench, Composite material, Electroplating, Layer (electronics), Electrical conductor
Abstract

To overcome the limitation of the sputtered Cu seed layer in electroplating of Cu interconnects imposed by the shadow effect, a new method for depositing a Cu seed layer on a 41 nm trench pattern based on combination of electroless plating (ELP) and electron-beam (E-Beam) evaporation was developed. A Cu seed layer formed by ELP alone was too thin to be used for electroplating due to its high resistivity. To solve this problem, an additional Cu layer was deposited on top of the trench by E-Beam evaporator to enhance the electrical conductivity of the Cu seed layer. The electrical resistivity of the resulting Cu layer was reduced to 4.8 μΩ cm, which was sufficient for the conductive seed layer for electroplating the 41 nm trench pattern. The gap-filling capability also improved and there were no voids or seams in the 41 nm trench pattern. The proposed method can be an effective solution for fabrication of a conductive seed layer to fill a 41 nm trench pattern by electroplating.

Published
2010
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34. Effect of micro and nanoparticle inorganic fillers on the field emission characteristics of photosensitive carbon nanotube pastes

Author

Yongho Seo, Jeungchoon Goak, Ki Buem Kim, Jihan Kim, H.S. Lee, K.S. Park, and Naesung Lee

Subjects
Materials science, Physics::Medical Physics, Mixing (process engineering), General Physics and Astronomy, Nanoparticle, Surfaces and Interfaces, General Chemistry, Carbon nanotube, Condensed Matter Physics, Surfaces, Coatings and Films, law.invention, Condensed Matter::Materials Science, Field electron emission, Inorganic filler, law, Composite material, Common emitter
Abstract

We successfully fabricated field emitter arrays of carbon nanotube (CNT) dots of 10 μm diameter with excellent field emission properties by using photosensitive CNT paste. The CNT paste was investigated in terms of morphologies, current–voltage properties, and luminous uniformities by varying the mixing ratios of micro and nanoparticle inorganic fillers and the amount of CNTs added into the paste. The 3:1 mixing of micro and nanoparticle fillers and the addition of 5% CNTs in the paste brought about the best field emission characteristics of dot-patterned CNT field emitter arrays.

Published
2010
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35. Effect of the Molding Conditions on Formability in Progressive Glass Molding Press

Author

D.S. Kim, K.S. Park, and T.S. Jung

Subjects
Pressing, Taguchi methods, Materials science, Aspheric lens, Design of experiments, Metallurgy, Formability, Mechanical engineering, Polishing, Molding (process), Grinding
Abstract

Remarkable progress had been made in both technology and production of optical elements including aspheric lens. In the past, precision optical glass lenses were produced through multiple processes such as grinding and polishing, but mass production of aspheric lenses requiring high accuracy and having complex profile was rather difficult. Against such a background, the high-precision optical GMP process was developed with an eye on mass production of precision optical glass pasts by molding press. This GMP process can produce with precision and good repeatability special form lenses such as for cameras, video cameras, aspheric lenses for optical items. In this study, Design Of Experiment(Taguchi method) was adopted to find a tendency of molding conditions that influence formability. Three main factors for molding conditions were selected based on pressure at pressing stage and temperature, pressure at cooling stage. Also, the DOE was carried out and the interference patterns were measured to evaluate the formability of GMP process. From the results, it was found that the cooling pressure is the most sensitive parameter for progressive GMP process.

Published
2009
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36. Influence of Human Allogenic Bone Marrow and Cord Blood–Derived Mesenchymal Stem Cell Secreting Trophic Factors on ATP (adenosine-5′-triphosphate)/ADP (adenosine-5′-diphosphate) Ratio and Insulin Secretory Function of Isolated Human Islets From Cadaveric Donor

Author

Y.S. Kim, S.H. Kim, C.H. Kwon, Jae-Won Joh, K.W. Kim, J.B. Park, S.H. Oh, M.S. Lee, K.S. Park, M.K. Lee, Y.R. Ahn, J.H. Kim, B.K. Choi, and S.J. Kim

Subjects
endocrine system, medicine.medical_specialty, endocrine system diseases, Angiogenesis, medicine.medical_treatment, Islets of Langerhans Transplantation, Bone Marrow Cells, Enzyme-Linked Immunosorbent Assay, Cell Separation, Biology, Islets of Langerhans, Adenosine Triphosphate, Internal medicine, Cadaver, Centrifugation, Density Gradient, medicine, Humans, Transplantation, geography, geography.geographical_feature_category, Insulin, Mesenchymal stem cell, Mesenchymal Stem Cells, Fetal Blood, Islet, Adenosine, Coculture Techniques, Tissue Donors, Adenosine Diphosphate, Diabetes Mellitus, Type 1, medicine.anatomical_structure, Endocrinology, Surgery, Hepatocyte growth factor, Cord Blood Stem Cell Transplantation, Bone marrow, medicine.drug
Abstract

Successful islet transplantation (ITx) is not only dependent on the number of islets, but also their quality, including viability, metabolic activity, and function. Islet quality decreases during cultivation after the isolation procedure. To overcome this obstacle, we established the practice of islet and mesenchymal stem cells (MSCs) coculture. This coculture condition improved the ATP (adenosine-5'-triphosphate)/ADP (adenosine-5'-diphosphate) ratio and insulin secretory function in vitro. It is believed that the enhancement of islet quality in islet-MSCs cocultures may be caused by the secretion of active agents by MSCs. Herein we have shown that interleukin-6 (IL-6), vascular endothelial growth factor-A (VEGF-A), hepatocyte growth factor (HGF), and transforming growth factor-beta (TGF-beta) were significantly increased as measured by enzyme-linked immunosorbent assay (ELISA) in MSCs-cultured medium, factors that have been shown to improve the survival, function, and angiogenesis/revascularization of islets. These results indicated that the quality of human islets was enhanced by trophic molecules secreted by MSCs, which influence the intracellular islet ATP content and insulin secretory function.

Published
2009
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37. Development of Functional Human Immune System With the Transplantations of Human Fetal Liver/Thymus Tissues and Expanded Hematopoietic Stem Cells in RAG2−/−γc−/− MICE

Author

S.K. Lee, B.-K. Choi, D.Y. Jung, C.H. Kwon, S.-J. Kim, Mijeong Kang, S.-Y. Joo, K.S. Park, G.O. Jung, G.S. Choi, J.B. Park, and Jae-Won Joh

Subjects
Fetal Tissue Transplantation, Transplantation, Heterologous, CD34, Antigens, CD34, Stem cell factor, Mice, SCID, Thymus Gland, Biology, Mice, Immune system, In vivo, Animals, Humans, Mice, Knockout, Transplantation, Hematopoietic Stem Cell Transplantation, Flow Cytometry, Molecular biology, Liver Transplantation, DNA-Binding Proteins, Haematopoiesis, Liver, Lymphocyte Transfusion, Immunology, Surgery, Subrenal Capsule Assay, Stem cell, Ex vivo
Abstract

Background There is an increasing need for suitable animal models for the study of the human immune system and disease. The purpose of this study was to develop a practical in vivo model of human immune cell repopulation using ex vivo expanded human fetal liver-derived CD34+ hematopoietic stem cells and subrenally coimplanted fetal liver/thymus tissues. Methods Freshly isolated fetal liver-derived CD34+ hematopoietic stem cells were frozen until injected and ex vivo expanded with various cytokines for 7 days. After fetal liver/thymus tissues were subrenally coimplanted into preirradiated Rag2−/−γc−/− mice, frozen and ex vivo expanded CD34+ cells were injected intravenously. The peripheral blood of the mice was monitored for the detection of human cell engraftment using flow cytometry. Then we confirmed human T-cell function by in vitro function assays. Results After fetal liver/thymus tissues were coimplanted into the irradiated Rag2−/−γc−/− mice, with frozen and ex vivo expanded CD34+ hematopoietic stem cells, human cell engraftments were determined using hCD45 and multilineage markers. The cultured cells with the cytokine combination of stem cell factor, thrombopoietin, Flk2/Flk3 ligand (FL), and interleukin-3 showed stable and long-term engraftment compared to other combinations. The ex vivo expanded human fetal liver-derived CD34+ hematopoietic stem cells, under our culture conditions, accomplished a large volume of expanded cells that were sustained, demonstrating self-renewal of the evaluated markers, which may have indicated long- term repopulation activity. Conclusion The results of this study demonstrated a practical mouse model of expanded human immune cells especially T cells in Rag2−/−γc−/− mice.

Published
2009
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38. Use of Epigenetic Modification to Induce FOXP3 Expression in Naïve T Cells

Author

J.H. Kwan, C. Moon, Sung Joo Kim, S.H. Kim, K.S. Park, H.S. Lee, B.K. Choi, G.S. Choi, J.B. Park, and Jae-Won Joh

Subjects
CD4-Positive T-Lymphocytes, T-Lymphocytes, Blotting, Western, chemical and pharmacologic phenomena, Biology, Decitabine, T-Lymphocytes, Regulatory, Immunophenotyping, Mice, Interleukin 21, medicine, Animals, Humans, Cytotoxic T cell, IL-2 receptor, Interleukin-7 receptor, DNA Modification Methylases, Mice, Inbred BALB C, Transplantation, Interleukin-2 Receptor alpha Subunit, CD28, FOXP3, Forkhead Transcription Factors, hemic and immune systems, T lymphocyte, Molecular biology, Trichostatin A, Gene Expression Regulation, Immunology, Azacitidine, Surgery, Spleen, medicine.drug
Abstract

We investigated whether epigenetic modification agents can convert naïve T cells to regulatory T cells (T(regs)) which are responsible for limiting immune responses and maintaining self-tolerance. We treated splenic CD4(+)/CD25(-) naïve T cells from BALB/c mice with the DNA-methyltransferase inhibitor 5-aza-2'-deoxycytidine (5AzaD) or the histone protein deacetylase (HDAC) inhibitor Trichostatin A (TSA), and measured the effects on the expression of FOXP3, which encodes a transcription factor (FOXP3) that regulates T(reg) development. FOXP3 expression in naïve T cells was increased by 5AzaD or TSA treatment, administered 72 hours after T-cell receptor (TCR) stimulation with anti-CD3 plus anti-CD28. The T(regs) induced by 5AzaD or TSA expressed greater amounts of the FOXP3 protein than the control and the natural T(regs). The analysis of T(reg)-associated markers also showed T(reg) phenotypes (CD25(+)/CTLA4(+)/GITR(+)/CD127(-)). Finally, the induced T(reg) population also displayed T-cell suppression. These data suggested that epigenetic modification agents can induce FOXP3 expression, promoting the conversion of naïve T cells to T(regs).

Published
2009
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39. Reconstitution of Human Lymphocytes Following Ex Vivo Expansion of Human Umbilical Cord Blood CD34+ Cells and Transplantation in Rag2−/− γc−/− Mice Model

Author

S.H. Kim, J.M. Chun, S.K. Lee, C. Moon, Jae-Won Joh, C.H. Kwon, G.O. Jung, S.Y. Joo, B.K. Choi, S.J. Kim, J.B. Park, G.S. Choi, and K.S. Park

Subjects
Umbilical Veins, Cell Transplantation, Lymphocyte, Transplantation, Heterologous, Cell Culture Techniques, Antigens, CD34, Stem cell factor, CD19, Mice, Antigens, CD, medicine, Animals, Humans, Mice, Knockout, Transplantation, biology, Infant, Newborn, Fetal Blood, Hematopoietic Stem Cells, Molecular biology, Recombinant Proteins, DNA-Binding Proteins, Haematopoiesis, medicine.anatomical_structure, Immunology, biology.protein, Leukocyte Common Antigens, Interleukin-3, Surgery, Bone marrow, Stem cell, Ex vivo
Abstract

Background. Due to ethical issues, in vivo studies of the human immune system have been difficult. Thus, small-animal xenotransplantation models have been employed, although they scarcely sustain a human immune response. In this study, we compared human cell repopulation tendencies and functionality in Rag2 -/- γc -/- mice following various ex vivo expanded human hematopoietic stem cells (HSCs). Methods. Human umbilical cord blood (UCB) CD34 + cells were cultured for 7 days with a cytokine combination of stem cell factor, Flk2/Flt3 ligand, and thrombopoietin, with absence or presence of rhIL-3, then transplanted into Rag2 -/- γc -/- mice. Reconstituted human lymphocytes were analyzed based on the expression of CD45 as well as CD3, CD19, and CD56 in peripheral blood (PB) until 16 weeks after transplantation. BrdU assay and functional analysis of reconstituted human lymphocytes used PHA- or rhIL-2-stimulated splenocytes and bone marrow cells from recipient mice. Results. The percentage of human CD45 dim cells, not CD45 bright cells, in PB of mice transplanted with cultured HSCs with rhIL-3 was much higher than in the group without rhIL-3 (approximately 2.5-fold at week 10 posttransplantation). The humanized mice showed systemic repopulation with a comprehensive array of human lymphohematopoietic cells, including T, B, natural killer (NK) cells, and even dendritic cells. However, the expression level was also dim. The number of CD3 + T cells and CD56 + NK cells was especially increased in the presence of rhIL-3. In addition, after in vitro restimulation proliferation assays and NK activity of interferon-y secretion showed greater effects in the presence of rhIL-3. Conclusion. These data suggested that the development of a diverse repopulation of human lymphocytes was possible in Rag2 -/- γc -/- mice after transplantation of cultured UCB CD34 + HSCs with interleukin-3.

Published
2008
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40. Measurement of the ratio B(D0→π+π−π0)/B(D0→K−π+π0) and the time-integrated CP asymmetry in D0→π+π−π0

Author

K. Arinstein, I. Adachi, H. Aihara, V. Aulchenko, T. Aushev, T. Aziz, S. Bahinipati, A.M. Bakich, V. Balagura, E. Barberio, A. Bay, I. Bedny, K. Belous, V. Bhardwaj, U. Bitenc, S. Blyth, A. Bondar, A. Bozek, M. Bračko, T.E. Browder, Y. Chao, A. Chen, W.T. Chen, B.G. Cheon, R. Chistov, I.-S. Cho, Y. Choi, S. Cole, J. Dalseno, M. Danilov, M. Dash, A. Drutskoy, S. Eidelman, D. Epifanov, N. Gabyshev, P. Goldenzweig, B. Golob, H. Ha, J. Haba, K. Hara, K. Hayasaka, H. Hayashii, M. Hazumi, Y. Hoshi, W.-S. Hou, T. Iijima, K. Inami, A. Ishikawa, H. Ishino, R. Itoh, M. Iwasaki, Y. Iwasaki, N.J. Joshi, D.H. Kah, H. Kaji, J.H. Kang, N. Katayama, H. Kawai, T. Kawasaki, H. Kichimi, S.K. Kim, Y.J. Kim, K. Kinoshita, S. Korpar, Y. Kozakai, P. Križan, P. Krokovny, R. Kumar, C.C. Kuo, Y. Kuroki, A. Kuzmin, Y.-J. Kwon, J.S. Lange, J.S. Lee, M.J. Lee, S.E. Lee, T. Lesiak, A. Limosani, S.-W. Lin, C. Liu, Y. Liu, D. Liventsev, F. Mandl, S. McOnie, W. Mitaroff, K. Miyabayashi, H. Miyake, H. Miyata, Y. Miyazaki, R. Mizuk, G.R. Moloney, T. Mori, E. Nakano, M. Nakao, S. Nishida, O. Nitoh, S. Ogawa, T. Ohshima, S. Okuno, H. Ozaki, P. Pakhlov, G. Pakhlova, C.W. Park, H. Park, K.S. Park, R. Pestotnik, L.E. Piilonen, A. Poluektov, H. Sahoo, Y. Sakai, O. Schneider, J. Schümann, C. Schwanda, A.J. Schwartz, K. Senyo, M.E. Sevior, M. Shapkin, V. Shebalin, H. Shibuya, J.-G. Shiu, B. Shwartz, J.B. Singh, A. Sokolov, A. Somov, S. Stanič, M. Starič, T. Sumiyoshi, S.Y. Suzuki, F. Takasaki, M. Tanaka, G.N. Taylor, Y. Teramoto, I. Tikhomirov, S. Uehara, K. Ueno, T. Uglov, Y. Unno, S. Uno, Y. Usov, G. Varner, K. Vervink, S. Villa, A. Vinokurova, C.H. Wang, M.-Z. Wang, P. Wang, X.L. Wang, Y. Watanabe, E. Won, B.D. Yabsley, H. Yamamoto, Y. Yamashita, C.C. Zhang, Z.P. Zhang, V. Zhilich, V. Zhulanov, A. Zupanc, and O. Zyukova

Subjects
Physics, Nuclear and High Energy Physics, 010308 nuclear & particles physics, Branching fraction, Analytical chemistry, Value (computer science), Inverse, 01 natural sciences, law.invention, KEKB, law, 0103 physical sciences, Pi, 010306 general physics, Collider
Abstract

We report a high-statistics measurement of the relative branching fraction Br(D0 --> pi+pi-pi0)/Br(D0 --> K-pi+pi0). A 357 inverse fb data sample collected with the Belle detector at the KEKB asymmetric-energy e+e- collider was used for the analysis. The relative branching fraction Br(D0 --> pi+pi-pi0)/Br(D0 --> K-pi+pi0) is determined with an accuracy comparable to the latest world average value.

Published
2008
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41. Search for new phenomena in monophoton final states in proton–proton collisions at s=8 TeV

Author

Khachatryan, V. Sirunyan, A.M. Tumasyan, A. Adam, W. Bergauer, T. Dragicevic, M. Erö, J. Friedl, M. Frühwirth, R. Ghete, V.M. Hartl, C. Hörmann, N. Hrubec, J. Jeitler, M. Kiesenhofer, W. Knünz, V. Krammer, M. Krätschmer, I. Liko, D. Mikulec, I. Rabady, D. Rahbaran, B. Rohringer, H. Schöfbeck, R. Strauss, J. Treberer-Treberspurg, W. Waltenberger, W. Wulz, C.-E. Mossolov, V. Shumeiko, N. Suarez Gonzalez, J. Alderweireldt, S. Bansal, M. Bansal, S. Cornelis, T. De Wolf, E.A. Janssen, X. Knutsson, A. Lauwers, J. Luyckx, S. Ochesanu, S. Rougny, R. Van De Klundert, M. Van Haevermaet, H. Van Mechelen, P. Van Remortel, N. Van Spilbeeck, A. Blekman, F. Blyweert, S. D'Hondt, J. Daci, N. Heracleous, N. Keaveney, J. Lowette, S. Maes, M. Olbrechts, A. Python, Q. Strom, D. Tavernier, S. Van Doninck, W. Van Mulders, P. Van Onsem, G.P. Villella, I. Caillol, C. Clerbaux, B. De Lentdecker, G. Dobur, D. Favart, L. Gay, A.P.R. Grebenyuk, A. Léonard, A. Mohammadi, A. Perniè, L. Reis, T. Seva, T. Thomas, L. Vander Velde, C. Vanlaer, P. Wang, J. Zenoni, F. Adler, V. Beernaert, K. Benucci, L. Cimmino, A. Costantini, S. Crucy, S. Dildick, S. Fagot, A. Garcia, G. Mccartin, J. Ocampo Rios, A.A. Ryckbosch, D. Salva Diblen, S. Sigamani, M. Strobbe, N. Thyssen, F. Tytgat, M. Yazgan, E. Zaganidis, N. Basegmez, S. Beluffi, C. Bruno, G. Castello, R. Caudron, A. Ceard, L. Da Silveira, G.G. Delaere, C. du Pree, T. Favart, D. Forthomme, L. Giammanco, A. Hollar, J. Jafari, A. Jez, P. Komm, M. Lemaitre, V. Nuttens, C. Pagano, D. Perrini, L. Pin, A. Piotrzkowski, K. Popov, A. Quertenmont, L. Selvaggi, M. Vidal Marono, M. Vizan Garcia, J.M. Beliy, N. Caebergs, T. Daubie, E. Hammad, G.H. Aldá Júnior, W.L. Alves, G.A. Brito, L. Correa Martins Junior, M. Dos Reis Martins, T. Mora Herrera, C. Pol, M.E. Carvalho, W. Chinellato, J. Custódio, A. Da Costa, E.M. De Jesus Damiao, D. De Oliveira Martins, C. Fonseca De Souza, S. Malbouisson, H. Matos Figueiredo, D. Mundim, L. Nogima, H. Prado Da Silva, W.L. Santaolalla, J. Santoro, A. Sznajder, A. Tonelli Manganote, E.J. Vilela Pereira, A. Bernardes, C.A. Dogra, S. Fernandez Perez Tomei, T.R. Gregores, E.M. Mercadante, P.G. Novaes, S.F. Padula, S.S. Aleksandrov, A. Genchev, V. Iaydjiev, P. Marinov, A. Piperov, S. Rodozov, M. Sultanov, G. Vutova, M. Dimitrov, A. Glushkov, I. Hadjiiska, R. Litov, L. Pavlov, B. Petkov, P. Bian, J.G. Chen, G.M. Chen, H.S. Chen, M. Cheng, T. Du, R. Jiang, C.H. Plestina, R. Romeo, F. Tao, J. Wang, Z. Asawatangtrakuldee, C. Ban, Y. Li, Q. Liu, S. Mao, Y. Qian, S.J. Wang, D. Zou, W. Avila, C. Chaparro Sierra, L.F. Florez, C. Gomez, J.P. Gomez Moreno, B. Sanabria, J.C. Godinovic, N. Lelas, D. Polic, D. Puljak, I. Antunovic, Z. Kovac, M. Brigljevic, V. Kadija, K. Luetic, J. Mekterovic, D. Sudic, L. Attikis, A. Mavromanolakis, G. Mousa, J. Nicolaou, C. Ptochos, F. Razis, P.A. Bodlak, M. Finger, M. Finger, M., Jr. Assran, Y. Elgammal, S. Mahmoud, M.A. Radi, A. Kadastik, M. Murumaa, M. Raidal, M. Tiko, A. Eerola, P. Fedi, G. Voutilainen, M. Härkönen, J. Karimäki, V. Kinnunen, R. Kortelainen, M.J. Lampén, T. Lassila-Perini, K. Lehti, S. Lindén, T. Luukka, P. Mäenpää, T. Peltola, T. Tuominen, E. Tuominiemi, J. Tuovinen, E. Wendland, L. Talvitie, J. Tuuva, T. Besancon, M. Couderc, F. Dejardin, M. Denegri, D. Fabbro, B. Faure, J.L. Favaro, C. Ferri, F. Ganjour, S. Givernaud, A. Gras, P. Hamel de Monchenault, G. Jarry, P. Locci, E. Malcles, J. Neveu, J. Rander, J. Rosowsky, A. Titov, M. Baffioni, S. Beaudette, F. Busson, P. Charlot, C. Dahms, T. Dalchenko, M. Dobrzynski, L. Filipovic, N. Florent, A. Granier de Cassagnac, R. Mastrolorenzo, L. Miné, P. Mironov, C. Naranjo, I.N. Nguyen, M. Ochando, C. Paganini, P. Regnard, S. Salerno, R. Sauvan, J.B. Sirois, Y. Veelken, C. Yilmaz, Y. Zabi, A. Agram, J.-L. Andrea, J. Aubin, A. Bloch, D. Brom, J.-M. Chabert, E.C. Collard, C. Conte, E. Fontaine, J.-C. Gelé, D. Goerlach, U. Goetzmann, C. Le Bihan, A.-C. Van Hove, P. Gadrat, S. Beauceron, S. Beaupere, N. Boudoul, G. Bouvier, E. Brochet, S. Carrillo Montoya, C.A. Chasserat, J. Chierici, R. Contardo, D. Depasse, P. El Mamouni, H. Fan, J. Fay, J. Gascon, S. Gouzevitch, M. Ille, B. Kurca, T. Lethuillier, M. Mirabito, L. Perries, S. Ruiz Alvarez, J.D. Sabes, D. Sgandurra, L. Sordini, V. Vander Donckt, M. Verdier, P. Viret, S. Xiao, H. Rurua, L. Autermann, C. Beranek, S. Bontenackels, M. Edelhoff, M. Feld, L. Heister, A. Hindrichs, O. Klein, K. Ostapchuk, A. Raupach, F. Sammet, J. Schael, S. Weber, H. Wittmer, B. Zhukov, V. Ata, M. Brodski, M. Dietz-Laursonn, E. Duchardt, D. Erdmann, M. Fischer, R. Güth, A. Hebbeker, T. Heidemann, C. Hoepfner, K. Klingebiel, D. Knutzen, S. Kreuzer, P. Merschmeyer, M. Meyer, A. Millet, P. Olschewski, M. Padeken, K. Papacz, P. Reithler, H. Schmitz, S.A. Sonnenschein, L. Teyssier, D. Thüer, S. Weber, M. Cherepanov, V. Erdogan, Y. Flügge, G. Geenen, H. Geisler, M. Haj Ahmad, W. Hoehle, F. Kargoll, B. Kress, T. Kuessel, Y. Künsken, A. Lingemann, J. Nowack, A. Nugent, I.M. Perchalla, L. Pooth, O. Stahl, A. Asin, I. Bartosik, N. Behr, J. Behrenhoff, W. Behrens, U. Bell, A.J. Bergholz, M. Bethani, A. Borras, K. Burgmeier, A. Cakir, A. Calligaris, L. Campbell, A. Choudhury, S. Costanza, F. Diez Pardos, C. Dolinska, G. Dooling, S. Dorland, T. Eckerlin, G. Eckstein, D. Eichhorn, T. Flucke, G. Garay Garcia, J. Geiser, A. Gunnellini, P. Hauk, J. Hempel, M. Horton, D. Jung, H. Kalogeropoulos, A. Kasemann, M. Katsas, P. Kieseler, J. Kleinwort, C. Korol, I. Krücker, D. Lange, W. Leonard, J. Lipka, K. Lobanov, A. Lohmann, W. Lutz, B. Mankel, R. Marfin, I. Melzer-Pellmann, I.-A. Meyer, A.B. Mittag, G. Mnich, J. Mussgiller, A. Naumann-Emme, S. Nayak, A. Novgorodova, O. Ntomari, E. Perrey, H. Pitzl, D. Placakyte, R. Raspereza, A. Ribeiro Cipriano, P.M. Roland, B. Ron, E. Sahin, M.Ö. Salfeld-Nebgen, J. Saxena, P. Schmidt, R. Schoerner-Sadenius, T. Schröder, M. Seitz, C. Spannagel, S. Vargas Trevino, A.D.R. Walsh, R. Wissing, C. Aldaya Martin, M. Blobel, V. Centis Vignali, M. Draeger, A.R. Erfle, J. Garutti, E. Goebel, K. Görner, M. Haller, J. Hoffmann, M. Höing, R.S. Kirschenmann, H. Klanner, R. Kogler, R. Lange, J. Lapsien, T. Lenz, T. Marchesini, I. Ott, J. Peiffer, T. Perieanu, A. Pietsch, N. Poehlsen, J. Poehlsen, T. Rathjens, D. Sander, C. Schettler, H. Schleper, P. Schlieckau, E. Schmidt, A. Seidel, M. Sola, V. Stadie, H. Steinbrück, G. Troendle, D. Usai, E. Vanelderen, L. Vanhoefer, A. Barth, C. Baus, C. Berger, J. Böser, C. Butz, E. Chwalek, T. De Boer, W. Descroix, A. Dierlamm, A. Feindt, M. Frensch, F. Giffels, M. Gilbert, A. Hartmann, F. Hauth, T. Husemann, U. Katkov, I. Kornmayer, A. Kuznetsova, E. Lobelle Pardo, P. Mozer, M.U. Müller, T. Nürnberg, A. Quast, G. Rabbertz, K. Röcker, S. Simonis, H.J. Stober, F.M. Ulrich, R. Wagner-Kuhr, J. Wayand, S. Weiler, T. Wolf, R. Anagnostou, G. Daskalakis, G. Geralis, T. Giakoumopoulou, V.A. Kyriakis, A. Loukas, D. Markou, A. Markou, C. Psallidas, A. Topsis-Giotis, I. Agapitos, A. Kesisoglou, S. Panagiotou, A. Saoulidou, N. Stiliaris, E. Aslanoglou, X. Evangelou, I. Flouris, G. Foudas, C. Kokkas, P. Manthos, N. Papadopoulos, I. Paradas, E. Strologas, J. Bencze, G. Hajdu, C. Hidas, P. Horvath, D. Sikler, F. Veszpremi, V. Vesztergombi, G. Zsigmond, A.J. Beni, N. Czellar, S. Karancsi, J. Molnar, J. Palinkas, J. Szillasi, Z. Makovec, A. Raics, P. Trocsanyi, Z.L. Ujvari, B. Swain, S.K. Beri, S.B. Bhatnagar, V. Gupta, R. Bhawandeep, U. Kalsi, A.K. Kaur, M. Kumar, R. Mittal, M. Nishu, N. Singh, J.B. Kumar, A. Kumar, A. Ahuja, S. Bhardwaj, A. Choudhary, B.C. Kumar, A. Malhotra, S. Naimuddin, M. Ranjan, K. Sharma, V. Banerjee, S. Bhattacharya, S. Chatterjee, K. Dutta, S. Gomber, B. Jain, S. Jain, S. Khurana, R. Modak, A. Mukherjee, S. Roy, D. Sarkar, S. Sharan, M. Abdulsalam, A. Dutta, D. Kailas, S. Kumar, V. Mohanty, A.K. Pant, L.M. Shukla, P. Topkar, A. Aziz, T. Banerjee, S. Bhowmik, S. Chatterjee, R.M. Dewanjee, R.K. Dugad, S. Ganguly, S. Ghosh, S. Guchait, M. Gurtu, A. Kole, G. Kumar, S. Maity, M. Majumder, G. Mazumdar, K. Mohanty, G.B. Parida, B. Sudhakar, K. Wickramage, N. Bakhshiansohi, H. Behnamian, H. Etesami, S.M. Fahim, A. Goldouzian, R. Khakzad, M. Mohammadi Najafabadi, M. Naseri, M. Paktinat Mehdiabadi, S. Rezaei Hosseinabadi, F. Safarzadeh, B. Zeinali, M. Felcini, M. Grunewald, M. Abbrescia, M. Calabria, C. Chhibra, S.S. Colaleo, A. Creanza, D. De Filippis, N. De Palma, M. Fiore, L. Iaselli, G. Maggi, G. Maggi, M. My, S. Nuzzo, S. Pompili, A. Pugliese, G. Radogna, R. Selvaggi, G. Sharma, A. Silvestris, L. Venditti, R. Abbiendi, G. Benvenuti, A.C. Bonacorsi, D. Braibant-Giacomelli, S. Brigliadori, L. Campanini, R. Capiluppi, P. Castro, A. Cavallo, F.R. Codispoti, G. Cuffiani, M. Dallavalle, G.M. Fabbri, F. Fanfani, A. Fasanella, D. Giacomelli, P. Grandi, C. Guiducci, L. Marcellini, S. Masetti, G. Montanari, A. Navarria, F.L. Perrotta, A. Primavera, F. Rossi, A.M. Rovelli, T. Siroli, G.P. Tosi, N. Travaglini, R. Albergo, S. Cappello, G. Chiorboli, M. Costa, S. Giordano, F. Potenza, R. Tricomi, A. Tuve, C. Barbagli, G. Ciulli, V. Civinini, C. D'Alessandro, R. Focardi, E. Gallo, E. Gonzi, S. Gori, V. Lenzi, P. Meschini, M. Paoletti, S. Sguazzoni, G. Tropiano, A. Benussi, L. Bianco, S. Fabbri, F. Piccolo, D. Ferretti, R. Ferro, F. Lo Vetere, M. Robutti, E. Tosi, S. Dinardo, M.E. Fiorendi, S. Gennai, S. Gerosa, R. Ghezzi, A. Govoni, P. Lucchini, M.T. Malvezzi, S. Manzoni, R.A. Martelli, A. Marzocchi, B. Menasce, D. Moroni, L. Paganoni, M. Pedrini, D. Ragazzi, S. Redaelli, N. Tabarelli de Fatis, T. Buontempo, S. Cavallo, N. Di Guida, S. Fabozzi, F. Iorio, A.O.M. Lista, L. Meola, S. Merola, M. Paolucci, P. Azzi, P. Bacchetta, N. Bisello, D. Branca, A. Carlin, R. Checchia, P. Dall'Osso, M. Dorigo, T. Galanti, M. Gasparini, U. Giubilato, P. Gozzelino, A. Kanishchev, K. Lacaprara, S. Margoni, M. Meneguzzo, A.T. Pazzini, J. Pozzobon, N. Ronchese, P. Simonetto, F. Torassa, E. Tosi, M. Vanini, S. Ventura, S. Zotto, P. Zucchetta, A. Zumerle, G. Gabusi, M. Ratti, S.P. Re, V. Riccardi, C. Salvini, P. Vitulo, P. Biasini, M. Bilei, G.M. Ciangottini, D. Fanò, L. Lariccia, P. Mantovani, G. Menichelli, M. Saha, A. Santocchia, A. Spiezia, A. Androsov, K. Azzurri, P. Bagliesi, G. Bernardini, J. Boccali, T. Broccolo, G. Castaldi, R. Ciocci, M.A. Dell'Orso, R. Donato, S. Fiori, F. Foà, L. Giassi, A. Grippo, M.T. Ligabue, F. Lomtadze, T. Martini, L. Messineo, A. Moon, C.S. Palla, F. Rizzi, A. Savoy-Navarro, A. Serban, A.T. Spagnolo, P. Squillacioti, P. Tenchini, R. Tonelli, G. Venturi, A. Verdini, P.G. Vernieri, C. Barone, L. Cavallari, F. D'imperio, G. Del Re, D. Diemoz, M. Jorda, C. Longo, E. Margaroli, F. Meridiani, P. Micheli, F. Nourbakhsh, S. Organtini, G. Paramatti, R. Rahatlou, S. Rovelli, C. Santanastasio, F. Soffi, L. Traczyk, P. Amapane, N. Arcidiacono, R. Argiro, S. Arneodo, M. Bellan, R. Biino, C. Cartiglia, N. Casasso, S. Costa, M. Degano, A. Demaria, N. Finco, L. Mariotti, C. Maselli, S. Migliore, E. Monaco, V. Musich, M. Obertino, M.M. Ortona, G. Pacher, L. Pastrone, N. Pelliccioni, M. Pinna Angioni, G.L. Potenza, A. Romero, A. Ruspa, M. Sacchi, R. Solano, A. Staiano, A. Tamponi, U. Belforte, S. Candelise, V. Casarsa, M. Cossutti, F. Della Ricca, G. Gobbo, B. La Licata, C. Marone, M. Schizzi, A. Umer, T. Zanetti, A. Chang, S. Kropivnitskaya, A. Nam, S.K. Kim, D.H. Kim, G.N. Kim, M.S. Kong, D.J. Lee, S. Oh, Y.D. Park, H. Sakharov, A. Son, D.C. Kim, T.J. Kim, J.Y. Song, S. Choi, S. Gyun, D. Hong, B. Jo, M. Kim, H. Kim, Y. Lee, B. Lee, K.S. Park, S.K. Roh, Y. Choi, M. Kim, J.H. Park, I.C. Ryu, G. Ryu, M.S. Choi, Y. Choi, Y.K. Goh, J. Kim, D. Kwon, E. Lee, J. Seo, H. Yu, I. Juodagalvis, A. Komaragiri, J.R. Md Ali, M.A.B. Casimiro Linares, E. Castilla-Valdez, H. De La Cruz-Burelo, E. Heredia-de La Cruz, I. Hernandez-Almada, A. Lopez-Fernandez, R. Sanchez-Hernandez, A. Carrillo Moreno, S. Vazquez Valencia, F. Pedraza, I. Salazar Ibarguen, H.A. Morelos Pineda, A. Krofcheck, D. Butler, P.H. Reucroft, S. Ahmad, A. Ahmad, M. Hassan, Q. Hoorani, H.R. Khan, W.A. Khurshid, T. Shoaib, M. Bialkowska, H. Bluj, M. Boimska, B. Frueboes, T. Górski, M. Kazana, M. Nawrocki, K. Romanowska-Rybinska, K. Szleper, M. Zalewski, P. Brona, G. Bunkowski, K. Cwiok, M. Dominik, W. Doroba, K. Kalinowski, A. Konecki, M. Krolikowski, J. Misiura, M. Olszewski, M. Wolszczak, W. Bargassa, P. Beirão Da Cruz E Silva, C. Faccioli, P. Ferreira Parracho, P.G. Gallinaro, M. Lloret Iglesias, L. Nguyen, F. Rodrigues Antunes, J. Seixas, J. Varela, J. Vischia, P. Afanasiev, S. Bunin, P. Golutvin, I. Karjavin, V. Konoplyanikov, V. Kozlov, G. Lanev, A. Malakhov, A. Matveev, V. Moisenz, P. Palichik, V. Perelygin, V. Savina, M. Shmatov, S. Shulha, S. Skatchkov, N. Smirnov, V. Zarubin, A. Golovtsov, V. Ivanov, Y. Kim, V. Levchenko, P. Murzin, V. Oreshkin, V. Smirnov, I. Sulimov, V. Uvarov, L. Vavilov, S. Vorobyev, A. Vorobyev, A. Andreev, Y. Dermenev, A. Gninenko, S. 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Hernandez, J.M. Josa, M.I. Navarro De Martino, E. Pérez-Calero Yzquierdo, A. Puerta Pelayo, J. Quintario Olmeda, A. Redondo, I. Romero, L. Soares, M.S. Albajar, C. de Trocóniz, J.F. Missiroli, M. Moran, D. Brun, H. Cuevas, J. Fernandez Menendez, J. Folgueras, S. Gonzalez Caballero, I. Brochero Cifuentes, J.A. Cabrillo, I.J. Calderon, A. Duarte Campderros, J. Fernandez, M. Gomez, G. Graziano, A. Lopez Virto, A. Marco, J. Marco, R. Martinez Rivero, C. Matorras, F. Munoz Sanchez, F.J. Piedra Gomez, J. Rodrigo, T. Rodríguez-Marrero, A.Y. Ruiz-Jimeno, A. Scodellaro, L. Vila, I. Vilar Cortabitarte, R. Abbaneo, D. Auffray, E. Auzinger, G. Bachtis, M. Baillon, P. Ball, A.H. Barney, D. Benaglia, A. Bendavid, J. Benhabib, L. Benitez, J.F. Bernet, C. Bloch, P. Bocci, A. Bonato, A. Bondu, O. Botta, C. Breuker, H. Camporesi, T. Cerminara, G. Colafranceschi, S. D'Alfonso, M. d'Enterria, D. Dabrowski, A. David, A. De Guio, F. De Roeck, A. De Visscher, S. Di Marco, E. Dobson, M. Dordevic, M. 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Miceli, T. Mulhearn, M. Pellett, D. Pilot, J. Ricci-Tam, F. Searle, M. Shalhout, S. Smith, J. Squires, M. Stolp, D. Tripathi, M. Wilbur, S. Yohay, R. Cousins, R. Everaerts, P. Farrell, C. Hauser, J. Ignatenko, M. Rakness, G. Takasugi, E. Valuev, V. Weber, M. Burt, K. Clare, R. Ellison, J. Gary, J.W. Hanson, G. Heilman, J. Ivova Rikova, M. Jandir, P. Kennedy, E. Lacroix, F. Long, O.R. Luthra, A. Malberti, M. Olmedo Negrete, M. Shrinivas, A. Sumowidagdo, S. Wimpenny, S. Branson, J.G. Cerati, G.B. Cittolin, S. D'Agnolo, R.T. Holzner, A. Kelley, R. Klein, D. Letts, J. Macneill, I. Olivito, D. Padhi, S. Palmer, C. Pieri, M. Sani, M. Sharma, V. Simon, S. Sudano, E. Tadel, M. Tu, Y. Vartak, A. Welke, C. Würthwein, F. Yagil, A. Barge, D. Bradmiller-Feld, J. Campagnari, C. Danielson, T. Dishaw, A. Dutta, V. Flowers, K. Franco Sevilla, M. Geffert, P. George, C. Golf, F. Gouskos, L. Incandela, J. Justus, C. Mccoll, N. Richman, J. Stuart, D. To, W. West, C. Yoo, J. Apresyan, A. Bornheim, A. 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Joshi, U. Kaadze, K. Klima, B. Kreis, B. Kwan, S. Linacre, J. Lincoln, D. Lipton, R. Liu, T. Lykken, J. Maeshima, K. Marraffino, J.M. Martinez Outschoorn, V.I. Maruyama, S. Mason, D. McBride, P. Merkel, P. Mishra, K. Mrenna, S. Musienko, Y. Nahn, S. Newman-Holmes, C. O'Dell, V. Prokofyev, O. Sexton-Kennedy, E. Sharma, S. Soha, A. Spalding, W.J. Spiegel, L. Taylor, L. Tkaczyk, S. Tran, N.V. Uplegger, L. Vaandering, E.W. Vidal, R. Whitbeck, A. Whitmore, J. Yang, F. Acosta, D. Avery, P. Bortignon, P. Bourilkov, D. Carver, M. Curry, D. Das, S. De Gruttola, M. Di Giovanni, G.P. Field, R.D. Fisher, M. Furic, I.K. Hugon, J. Konigsberg, J. Korytov, A. Kypreos, T. Low, J.F. Matchev, K. Milenovic, P. Mitselmakher, G. Muniz, L. Rinkevicius, A. Shchutska, L. Snowball, M. Sperka, D. Yelton, J. Zakaria, M. Hewamanage, S. Linn, S. Markowitz, P. Martinez, G. Rodriguez, J.L. Adams, T. Askew, A. Bochenek, J. Diamond, B. Haas, J. Hagopian, S. Hagopian, V. Johnson, K.F. Prosper, H. Veeraraghavan, V. Weinberg, M. Baarmand, M.M. Hohlmann, M. Kalakhety, H. Yumiceva, F. Adams, M.R. Apanasevich, L. Bazterra, V.E. Berry, D. Betts, R.R. Bucinskaite, I. Cavanaugh, R. Evdokimov, O. Gauthier, L. Gerber, C.E. Hofman, D.J. Khalatyan, S. Kurt, P. Moon, D.H. O'Brien, C. Silkworth, C. Turner, P. Varelas, N. Bilki, B. Clarida, W. Dilsiz, K. Duru, F. Haytmyradov, M. Merlo, J.-P. Mermerkaya, H. Mestvirishvili, A. Moeller, A. Nachtman, J. Ogul, H. Onel, Y. Ozok, F. Penzo, A. Rahmat, R. Sen, S. Tan, P. Tiras, E. Wetzel, J. Yi, K. Barnett, B.A. Blumenfeld, B. Bolognesi, S. Fehling, D. Gritsan, A.V. Maksimovic, P. Martin, C. Swartz, M. Baringer, P. Bean, A. Benelli, G. Bruner, C. Kenny III, R.P. Malek, M. Murray, M. Noonan, D. Sanders, S. Sekaric, J. Stringer, R. Wang, Q. Wood, J.S. Chakaberia, I. Ivanov, A. Khalil, S. Makouski, M. Maravin, Y. Saini, L.K. Shrestha, S. Skhirtladze, N. Svintradze, I. Gronberg, J. Lange, D. Rebassoo, F. Wright, D. Baden, A. Belloni, A. Calvert, B. Eno, S.C. Gomez, J.A. Hadley, N.J. Kellogg, R.G. Kolberg, T. Lu, Y. Marionneau, M. Mignerey, A.C. Pedro, K. Skuja, A. Tonjes, M.B. Tonwar, S.C. Apyan, A. Barbieri, R. Bauer, G. Busza, W. Cali, I.A. Chan, M. Di Matteo, L. Gomez Ceballos, G. Goncharov, M. Gulhan, D. Klute, M. Lai, Y.S. Lee, Y.-J. Levin, A. Luckey, P.D. Ma, T. Paus, C. Ralph, D. Roland, C. Roland, G. Stephans, G.S.F. Stöckli, F. Sumorok, K. Velicanu, D. Veverka, J. Wyslouch, B. Yang, M. Zanetti, M. Zhukova, V. Dahmes, B. Gude, A. Kao, S.C. Klapoetke, K. Kubota, Y. Mans, J. Pastika, N. Rusack, R. Singovsky, A. Tambe, N. Turkewitz, J. Acosta, J.G. Oliveros, S. Avdeeva, E. Bloom, K. Bose, S. Claes, D.R. Dominguez, A. Gonzalez Suarez, R. Keller, J. Knowlton, D. Kravchenko, I. Lazo-Flores, J. Malik, S. Meier, F. Ratnikov, F. Snow, G.R. Zvada, M. Dolen, J. Godshalk, A. Iashvili, I. Kharchilava, A. Kumar, A. Rappoccio, S. Alverson, G. Barberis, E. Baumgartel, D. Chasco, M. Haley, J. Massironi, A. Morse, D.M. Nash, D. Orimoto, T. Trocino, D. Wang, R.-J. Wood, D. Zhang, J. Hahn, K.A. Kubik, A. Mucia, N. Odell, N. Pollack, B. Pozdnyakov, A. Schmitt, M. Stoynev, S. Sung, K. Velasco, M. Won, S. Brinkerhoff, A. Chan, K.M. Drozdetskiy, A. Hildreth, M. Jessop, C. Karmgard, D.J. Kellams, N. Lannon, K. Luo, W. Lynch, S. Marinelli, N. Pearson, T. Planer, M. Ruchti, R. Valls, N. Wayne, M. Wolf, M. Woodard, A. Antonelli, L. Brinson, J. Bylsma, B. Durkin, L.S. Flowers, S. Hart, A. Hill, C. Hughes, R. Kotov, K. Ling, T.Y. Puigh, D. Rodenburg, M. Smith, G. Winer, B.L. Wolfe, H. Wulsin, H.W. Driga, O. Elmer, P. Hardenbrook, J. Hebda, P. Hunt, A. Koay, S.A. Lujan, P. Marlow, D. Medvedeva, T. Mooney, M. Olsen, J. Piroué, P. Quan, X. Saka, H. Stickland, D. Tully, C. Werner, J.S. Zuranski, A. Brownson, E. Mendez, H. Ramirez Vargas, J.E. Barnes, V.E. Benedetti, D. Bortoletto, D. De Mattia, M. Gutay, L. Hu, Z. Jha, M.K. Jones, M. Jung, K. Kress, M. Leonardo, N. Lopes Pegna, D. Maroussov, V. Miller, D.H. Neumeister, N. Radburn-Smith, B.C. Shi, X. Shipsey, I. Silvers, D. Svyatkovskiy, A. Wang, F. Xie, W. Xu, L. Yoo, H.D. Zablocki, J. Zheng, Y. Parashar, N. Stupak, J. Adair, A. Akgun, B. Ecklund, K.M. Geurts, F.J.M. Li, W. Michlin, B. Padley, B.P. Redjimi, R. Roberts, J. Zabel, J. Betchart, B. Bodek, A. Covarelli, R. de Barbaro, P. Demina, R. Eshaq, Y. Ferbel, T. Garcia-Bellido, A. Goldenzweig, P. Han, J. Harel, A. Khukhunaishvili, A. Korjenevski, S. Petrillo, G. Vishnevskiy, D. Ciesielski, R. Demortier, L. Goulianos, K. Lungu, G. Mesropian, C. Arora, S. Barker, A. Chou, J.P. Contreras-Campana, C. Contreras-Campana, E. Duggan, D. Ferencek, D. Gershtein, Y. Gray, R. Halkiadakis, E. Hidas, D. Kaplan, S. Lath, A. Panwalkar, S. Park, M. Patel, R. Salur, S. Schnetzer, S. Somalwar, S. Stone, R. Thomas, S. Thomassen, P. Walker, M. Rose, K. Spanier, S. York, A. Bouhali, O. Castaneda Hernandez, A. Eusebi, R. Flanagan, W. Gilmore, J. Kamon, T. Khotilovich, V. Krutelyov, V. Montalvo, R. Osipenkov, I. Pakhotin, Y. Perloff, A. Roe, J. Rose, A. Safonov, A. Suarez, I. Tatarinov, A. Akchurin, N. Cowden, C. Damgov, J. Dragoiu, C. Dudero, P.R. Faulkner, J. Kovitanggoon, K. Kunori, S. Lee, S.W. Libeiro, T. Volobouev, I. Appelt, E. Delannoy, A.G. Greene, S. Gurrola, A. Johns, W. Maguire, C. Mao, Y. Melo, A. Sharma, M. Sheldon, P. Snook, B. Tuo, S. Velkovska, J. Arenton, M.W. Boutle, S. Cox, B. Francis, B. Goodell, J. Hirosky, R. Ledovskoy, A. Li, H. Lin, C. Neu, C. Wood, J. Clarke, C. Harr, R. Karchin, P.E. Kottachchi Kankanamge Don, C. Lamichhane, P. Sturdy, J. Belknap, D.A. Carlsmith, D. Cepeda, M. Dasu, S. Dodd, L. Duric, S. Friis, E. Hall-Wilton, R. Herndon, M. Hervé, A. Klabbers, P. Lanaro, A. Lazaridis, C. Levine, A. Loveless, R. Mohapatra, A. Ojalvo, I. Perry, T. Pierro, G.A. Polese, G. Ross, I. Sarangi, T. Savin, A. Smith, W.H. Taylor, D. Verwilligen, P. Vuosalo, C. Woods, N. CMS Collaboration

Subjects
High Energy Physics::Experiment, Nuclear Experiment
Abstract

Results are presented from a search for new physics in final states containing a photon and missing transverse momentum. The data correspond to an integrated luminosity of 19.6 fb−1 collected in proton–proton collisions at s=8 TeV with the CMS experiment at the LHC. No deviation from the standard model predictions is observed for these final states. New, improved limits are set on dark matter production and on parameters of models with large extra dimensions. In particular, the first limits from the LHC on branon production are found and significantly extend previous limits from LEP and the Tevatron. An upper limit of 14.0 fb on the cross section is set at the 95% confidence level for events with a monophoton final state with photon transverse momentum greater than 145 GeV and missing transverse momentum greater than 140 GeV. © 2016 CERN for the benefit of the CMS Collaboration

Published
2016

42. Unconstrained detection of freezing of Gait in Parkinson's disease patients using smartphone

Author

Sungjun Kwon, Woong-Woo Lee, Chae Won Shin, Beom S. Jeon, K.S. Park, Hyeyoung Park, Hyo Seon Jeon, Won-Jin Yi, Hong Ji Lee, Hanbyul Kim, and Sang Kyong Kim

Subjects
Male, medicine.medical_specialty, Parkinson's disease, Waist, Activities of daily living, Walking, Accelerometer, Health problems, Accelerometry, medicine, Humans, Gait, Gait Disorders, Neurologic, Aged, business.industry, Body position, Parkinson Disease, Fall risk, medicine.disease, medicine.anatomical_structure, Physical therapy, Accidental Falls, Female, Smartphone, Ankle, business, Algorithms
Abstract

Freezing of gait (FOG) is a common motor impairment to suffer an inability to walk, experienced by Parkinson's disease (PD) patients. FOG interferes with daily activities and increases fall risk, which can cause severe health problems. We propose a novel smartphone-based system to detect FOG symptoms in an unconstrained way. The feasibility of single device to sense gait characteristic was tested on the various body positions such as ankle, trouser pocket, waist and chest pocket. Using measured data from accelerometer and gyroscope in the smartphone, machine learning algorithm was applied to classify freezing episodes from normal walking. The performance of AdaBoost.M1 classifier showed the best sensitivity of 86% at the waist, 84% and 81% in the trouser pocket and at the ankle respectively, which is comparable to the results of previous studies.

Published
2015
Full Text
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44. Synthesis and Characterization of the ZnO-TiO2 Nanoparticles by a Hydrothermal Processing

Author

K.S. Park, Soo-Ryong Kim, Byung Ik Kim, Jong Kyu Lee, Dong Sik Bae, and June-Hee Kim

Subjects
Materials science, Precipitation (chemistry), Mechanical Engineering, Inorganic chemistry, Nanoparticle, chemistry.chemical_element, Zinc, Hydrothermal circulation, chemistry.chemical_compound, Ammonium hydroxide, chemistry, Chemical engineering, Mechanics of Materials, Particle, General Materials Science, Particle size, Zinc titanate
Abstract

Zinc titanate nanoparticles were prepared under high temperature and pressure conditions by precipitation from metal precursors with aqueous ammonium hydroxide. Zinc titanates powders were obtained in the temperature range of 180-230 for 4 h. The phase of synthesized particle with calcined at 800 for 2h. ZnTiO3, Zn2TiO4, Zn2Ti3O8, TiO2, ZnO. The average particle size and distribution of the synthesized zinc titanate nanoparticles were below 100 nm and narrow, respectively.

Published
2006
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45. Search for neutrinoless decays τ→3ℓ

Author

Y. Yusa, T. Nagamine, A. Yamaguchi, K. Abe, T. Abe, I. Adachi, H. Aihara, M. Akatsu, Y. Asano, V. Aulchenko, T. Aushev, S. Bahinipati, A.M. Bakich, E. Banas, I. Bedny, U. Bitenc, I. Bizjak, A. Bondar, A. Bozek, M. Bračko, T.E. Browder, M.-C. Chang, B.G. Cheon, R. Chistov, Y. Choi, A. Chuvikov, M. Danilov, L.Y. Dong, S. Eidelman, V. Eiges, Y. Enari, S. Fratina, N. Gabyshev, A. Garmash, T. Gershon, G. Gokhroo, B. Golob, J. Haba, H. Hayashii, M. Hazumi, L. Hinz, T. Hokuue, Y. Hoshi, W.-S. Hou, T. Iijima, K. Inami, A. Ishikawa, R. Itoh, H. Iwasaki, M. Iwasaki, J.H. Kang, J.S. Kang, P. Kapusta, N. Katayama, H. Kawai, T. Kawasaki, H. Kichimi, H.O. Kim, P. Koppenburg, S. Korpar, P. Križan, P. Krokovny, A. Kuzmin, Y.-J. Kwon, S.H. Lee, T. Lesiak, J. Li, S.-W. Lin, J. MacNaughton, T. Matsumoto, A. Matyja, Y. Mikami, W. Mitaroff, H. Miyata, D. Mohapatra, G.R. Moloney, T. Mori, Y. Nagasaka, E. Nakano, M. Nakao, H. Nakazawa, Z. Natkaniec, S. Nishida, O. Nitoh, T. Nozaki, S. Ogawa, T. Ohshima, T. Okabe, S. Okuno, S.L. Olsen, W. Ostrowicz, H. Ozaki, P. Pakhlov, H. Palka, H. Park, K.S. Park, N. Parslow, J.-P. Perroud, L.E. Piilonen, A. Poluektov, N. Root, H. Sagawa, S. Saitoh, Y. Sakai, T.R. Sarangi, O. Schneider, A.J. Schwartz, S. Semenov, K. Senyo, M.E. Sevior, H. Shibuya, B. Shwartz, J.B. Singh, N. Soni, S. Stanič, M. Starič, K. Sumisawa, T. Sumiyoshi, S. Suzuki, O. Tajima, F. Takasaki, K. Tamai, N. Tamura, M. Tanaka, Y. Teramoto, T. Tomura, T. Tsuboyama, T. Tsukamoto, S. Uehara, T. Uglov, Y. Unno, S. Uno, G. Varner, C.C. Wang, C.H. Wang, Y. Yamada, Y. Yamashita, M. Yamauchi, H. Yanai, J. Zhang, Z.P. Zhang, V. Zhilich, T. Ziegler, and D. Žontar

Subjects
Nuclear physics, Physics, Particle physics, Nuclear and High Energy Physics, KEKB, Electron–positron annihilation, TAU lepton flavor violation, Lepton
Abstract

We have searched for neutrinoless τ lepton decays into three charged leptons using an 87.1fb-1 data sample collected with the Belle detector at the KEKB e+e- collider. Since the number of signal candidate events is compatible with that expected from the background, we set 90% confidence level upper limits on the branching fractions in the range (1.9-3.5)×10-7 for various decay modes τ -→l-l+l- where l represents e or μ. © 2004 Published by Elsevier B.V.

Published
2004
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46. Rayleigh–Bénard convection of viscoelastic fluids in arbitrary finite domains

Author

K.S. Park and H.M. Park

Subjects
Fluid Flow and Transfer Processes, Convection, Hopf bifurcation, Physics, Hydrodynamic stability, Natural convection, Mechanical Engineering, Rayleigh number, Mechanics, Condensed Matter Physics, Deborah number, Physics::Fluid Dynamics, symbols.namesake, Classical mechanics, Chebyshev pseudospectral method, symbols, Rayleigh–Bénard convection
Abstract

In the present work, we consider the linear hydrodynamic stability problems of viscoelastic fluids in arbitrary finite domains. The effects of domain shapes on the critical Rayleigh number and convection pattern are investigated by means of a linear stability analysis employing a Chebyshev pseudospectral method. It is shown that the domain shape can change the viscoelastic parameter values where the Hopf bifurcation occurs in the Rayleigh–Benard convection. The results of the present investigation may be exploited to design shapes of convection box where the Hopf bifurcation occurs at realistic low values of Deborah number. This will enhance the usefulness of the natural convection system as a rheometry tool.

Published
2004
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47. Cytological observations of cucumber plants during induced resistance elicited by rhizobacteria

Author

K.S Park, Joseph W. Kloepper, W.D Fowler, Y.C Jeun, and C.H Kim

Subjects
Appressorium, biology, Inoculation, fungi, Colletotrichum orbiculare, food and beverages, Pseudomonas fluorescens, Rhizobacteria, biology.organism_classification, Microbiology, chemistry.chemical_compound, chemistry, Insect Science, Serratia marcescens, Agronomy and Crop Science, Pathogen, Salicylic acid
Abstract

Expression of induced resistance was cytologically compared between cucumber plants induced with either plant growth-promoting rhizobacteria (PGPR) or chemicals. Inoculation with PGPR strains Serratia marcescens (90–166) and Pseudomonas fluorescens (89B61) induced systemic protection in the aerial part of cucumber plants against the anthracnose pathogen Colletotrichum orbiculare. Disease development was significantly reduced in these plants compared to control plants that were not inoculated with the PGPR strains. Inoculation with the PGPR strains caused no visible toxicity, necrosis, or other morphological changes. Induction with dl -3-aminobutyric acid (BABA) or amino salicylic acid (ASA) also significantly reduced disease development. Soil drench with 10 mM BABA and 1.0 mM ASA-induced resistance in cucumber leaves without any toxicity to the plants. Higher concentrations of ASA (up to 10 mM) were phytotoxic, resulting in plant stunting and blighted appearance of leaves. Cytological studies using fluorescent microscopy revealed a higher frequency of autofluorescent epidermal cells, which are related to accumulation of phenolic compounds, at the sites of fungal penetration in plants induced with PGPR and challenged by the pathogen. Neither spore-germination rate nor formation of appressoria was affected by PGPR treatments. In contrast, both BABA and ASA significantly reduced spore-germination rate and appressoria formation, while there were no differences from controls in the frequency of autofluorescent epidermal cells at the sites of fungal penetration. Our findings suggest that PGPR and chemical inducers cause different plant responses during induced resistance.

Published
2004
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48. Search for the Electric Dipole Moment of the τ Lepton

Author

K. Inami, K. Abe, R. Abe, T. Abe, I. Adachi, H. Aihara, M. Akatsu, Y. Asano, T. Aso, V. Aulchenko, T. Aushev, A.M. Bakich, Y. Ban, E. Banas, P.K. Behera, I. Bizjak, A. Bondar, T.E. Browder, P. Chang, Y. Chao, B.G. Cheon, R. Chistov, Y. Choi, Y.K. Choi, L.Y. Dong, S. Eidelman, V. Eiges, Y. Enari, C. Fukunaga, N. Gabyshev, A. Garmash, T. Gershon, B. Golob, C. Hagner, F. Handa, T. Hara, H. Hayashii, M. Hazumi, I. Higuchi, T. Higuchi, T. Hokuue, Y. Hoshi, W.-S. Hou, H.-C. Huang, T. Igaki, T. Iijima, A. Ishikawa, H. Ishino, R. Itoh, H. Iwasaki, H.K. Jang, J.H. Kang, J.S. Kang, N. Katayama, H. Kawai, Y. Kawakami, N. Kawamura, T. Kawasaki, H. Kichimi, H.O. Kim, Hyunwoo Kim, J.H. Kim, S.K. Kim, S. Korpar, P. Krokovny, R. Kulasiri, A. Kuzmin, Y.-J. Kwon, J.S. Lange, G. Leder, S.H. Lee, J. Li, D. Liventsev, R.-S. Lu, J. MacNaughton, F. Mandl, T. Matsuishi, S. Matsumoto, T. Matsumoto, W. Mitaroff, H. Miyake, H. Miyata, T. Nagamine, Y. Nagasaka, T. Nakadaira, E. Nakano, M. Nakao, J.W. Nam, S. Nishida, T. Nozaki, S. Ogawa, T. Ohshima, T. Okabe, S. Okuno, S.L. Olsen, W. Ostrowicz, H. Ozaki, P. Pakhlov, H. Park, K.S. Park, L.S. Peak, J.-P. Perroud, L.E. Piilonen, K. Rybicki, H. Sagawa, S. Saitoh, Y. Sakai, M. Satapathy, O. Schneider, S. Semenov, K. Senyo, M.E. Sevior, H. Shibuya, B. Shwartz, V. Sidorov, J.B. Singh, N. Soni, S. Stanič, M. Starič, A. Sugi, A. Sugiyama, K. Sumisawa, T. Sumiyoshi, S. Suzuki, S.Y. Suzuki, T. Takahashi, F. Takasaki, K. Tamai, N. Tamura, J. Tanaka, M. Tanaka, G.N. Taylor, Y. Teramoto, S. Tokuda, T. Tomura, T. Tsuboyama, T. Tsukamoto, S. Uehara, Y. Unno, S. Uno, G. Varner, K.E. Varvell, C.C. Wang, Y. Watanabe, B.D. Yabsley, Y. Yamada, A. Yamaguchi, Y. Yamashita, Y. Yusa, Z.P. Zhang, V. Zhilich, and D. Žontar

Subjects
Physics, Nuclear and High Energy Physics, Particle physics, Electric dipole moment, Form factor (quantum field theory), FOS: Physical sciences, Observable, Optimal observable, Atomic and Molecular Physics, and Optics, High Energy Physics - Experiment, law.invention, High Energy Physics - Experiment (hep-ex), Dipole, CP violation, KEKB, law, Tau, Signature (topology), Collider, Lepton
Abstract

We have searched for a T/CP violation signature arising from an electric dipole form factor (d_tau) of the tau lepton in the e+e- -> tau+tau- reaction. Using an optimal observable method for 29.5 fb^{-1} of data collected with the Belle detector at the KEKB collider at sqrt{s}=10.58 GeV, we obtained the preliminary result Re(d_tau) = (1.15 +- 1.70) x 10^{-17} ecm and Im(d_tau) = (-0.83 +- 0.86) x 10^{-17} ecm for the real and imaginary parts of d_tau, respectively, and set the 95% confidence level limits -2.2 < Re(d_tau) < 4.5 (10^{-17} ecm) and -2.5 < Im(d_tau) < 0.8 (10^{-17} ecm)., Invited talk at the Seventh International Workshop on Tau Lepton Physics (TAU02), Santa Cruz, Ca, USA, Sept 2002, 8 pages, LaTeX, 19 eps figures

Published
2003
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49. Effects of Ascorbic Acid and Antioxidants on the Lipid Oxidation and Volatiles of Irradiated Ground Beef

Author

Dong U. Ahn, K. C. Nam, Byungrok Min, Seung-Cheol Lee, and K.S. Park

Subjects
Antioxidant, medicine.medical_treatment, Food preservation, food and beverages, chemistry.chemical_element, Shelf life, Ascorbic acid, Sulfur, chemistry, Biochemistry, Lipid oxidation, medicine, Tocopherol, Food science, Irradiation, Food Science
Abstract

Beef loins, aged for different lengths of time post slaughter, were treated with ionizing radiation, irradiated ground beef produced volatile sulfur compounds (S-volatiles) responsible for the unique irradiation odor and accelerated lipid oxidation. The quality charges by irradiation became greater as aging and storage time increased. During aerobic storage, the S-volatiles disappeared whereas volatile aldehydes drastically increased in irradiated beef.Addition of ascorhic acid at 0.1% (wt/wt) or sesanol) α-locopherol at each 0.01% level to ground breef before irradiation effectively reduced lipid oxidation and S volatiles. As storage time increased, however, the antioxident effect of sesanol + tocopherol in irradiated ground beef was superior to that of ascorbic acid.

Published
2003
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50. Study of →Dππ decays

Author

A Satpathy, K Abe, R Abe, T Abe, I Adachi, H Aihara, M Akatsu, Y Asano, T Aso, T Aushev, A.M Bakich, Y Ban, A Bay, I Bedny, P.K Behera, A Bondar, A Bozek, M Bračko, T.E Browder, B.C.K Casey, P Chang, Y Chao, K.-F Chen, B.G Cheon, R Chistov, S.-K Choi, Y Choi, M Danilov, L.Y Dong, S Eidelman, V Eiges, C Fukunaga, N Gabyshev, A Garmash, T Gershon, B Golob, J Haba, T Hara, N.C Hastings, H Hayashii, M Hazumi, I Higuchi, L Hinz, T Hokuue, W.-S Hou, H.-C Huang, T Igaki, Y Igarashi, T Iijima, K Inami, A Ishikawa, R Itoh, H Iwasaki, Y Iwasaki, H.K Jang, J.H Kang, P Kapusta, S.U Kataoka, N Katayama, H Kawai, Y Kawakami, N Kawamura, T Kawasaki, H Kichimi, D.W Kim, H.J Kim, Hyunwoo Kim, S.K Kim, K Kinoshita, S Kobayashi, P Krokovny, R Kulasiri, S Kumar, A Kuzmin, Y.-J Kwon, S.H Lee, J Li, D Liventsev, R.-S Lu, J MacNaughton, G Majumder, F Mandl, S Matsumoto, T Matsumoto, W Mitaroff, K Miyabayashi, H Miyake, H Miyata, T Mori, T Nagamine, Y Nagasaka, T Nakadaira, E Nakano, M Nakao, H Nakazawa, J.W Nam, Z Natkaniec, S Nishida, O Nitoh, S Noguchi, S Ogawa, T Ohshima, T Okabe, S Okuno, S.L Olsen, Y Onuki, W Ostrowicz, H Ozaki, P Pakhlov, H Palka, C.W Park, K.S Park, J.-P Perroud, M Peters, L.E Piilonen, K Rybicki, H Sagawa, S Saitoh, Y Sakai, M Satapathy, O Schneider, S Schrenk, C Schwanda, S Semenov, K Senyo, R Seuster, H Shibuya, V Sidorov, J.B Singh, N Soni, S Stanič, M Starič, A Sugi, K Sumisawa, T Sumiyoshi, S Suzuki, S.Y Suzuki, S.K Swain, T Takahashi, F Takasaki, K Tamai, N Tamura, J Tanaka, M Tanaka, G.N Taylor, Y Teramoto, T Tomura, K Trabelsi, T Tsuboyama, T Tsukamoto, S Uehara, K Ueno, S Uno, G Varner, C.H Wang, J.G Wang, M.-Z Wang, E Won, B.D Yabsley, Y Yamada, A Yamaguchi, Y Yamashita, M Yamauchi, H Yanai, Y Yuan, C.C Zhang, Z.P Zhang, and V Zhilich

Subjects
Nuclear physics, Hadronic decay, Physics, Nuclear and High Energy Physics, Particle physics, KEKB, Annihilation, Branching fraction, Pi, Omega
Abstract

We report on a study of $\bar{B^{0}} \to D^{(*) 0} \pi^+ \pi^-$ decays using 29.1 fb$^{-1}$ of $e^{+}e^{-}$ annihilation data recorded at the $\Upsilon(4S)$ resonance with the Belle detector at the KEKB storage ring. Making no assumptions about the intermediate mechanism, the branching fractions for $\bar{B}^0 \to D^0 \pi^+ \pi^-$ and $\bar{B}^0 \to D^{* 0} \pi^+ \pi^-$ are determined to be $(8.0 \pm 0.6 \pm 1.5) \times 10^{-4} $ and $ (6.2 \pm 1.2 \pm 1.8) \times 10^{-4}$ respectively. An analysis of $\bar{B^{0}} \to D^{0} \pi^+ \pi^-$ candidates yields to the first observation of the color-suppressed hadronic decay $\bar{B}^0 \to D^0 \rho^0$ with the branching fraction $(2.9 \pm 1.0 \pm 0.4) \times 10^{-4}$. We measure the ratio of branching fractions ${\mathcal B}(\bar{B^0} \to D^0 \rho^0) / {\mathcal B}(\bar{B^0} \to D^0 \omega)$ = 1.6 $\pm$ 0.8.

Published
2003
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