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232 results on '"KAIDA, S."'

1. Coherent photoproduction of the neutral pion and eta meson on the deuteron at incident energies below 1.15 GeV

Author

Ishikawa, T., Fix, A., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Iwata, T., Kaida, S., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Obara, Y., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H. Y.

Subjects
Nuclear Experiment, High Energy Physics - Experiment, Nuclear Theory
Abstract

Coherent photoproduction of the neutral pion and eta meson on the deuteron, $\gamma{d}${$\to$}$\pi^0\eta{d}$, has been experimentally studied at incident photon energies ranging from the reaction threshold to 1.15 GeV. The total cross section demonstrates a rapid rise below 1 GeV. The data are underestimated by the existing theoretical calculations based on quasi-free $\pi^0 \eta$ photoproduction on the nucleon followed by deuteron coalescence. At the same time, the data are rather well reproduced by the calculations taking into account the final-state interaction. We have also measured for the first time the differential cross sections: the $\pi^0 \eta$ invariant-mass distribution $d\sigma/dM_{\pi \eta}$, the $\pi^0 d$ invariant-mass distribution $d\sigma/dM_{\pi d}$, the $\eta d$ invariant-mass distribution $d\sigma/dM_{\eta d}$, and the distribution over the deuteron emission angle $d\sigma/d\Omega_d$ in the overall center-of-mass frame. The measured cross section $d\sigma/d\Omega_d$ does not exhibit strongly backward-peaking behavior predicted by the calculations. At all incident energies, an increase in $d\sigma/dM_{\eta d}$ near the $\eta d$ threshold is observed, which indicates a bound or virtual $\eta d$ state resulting from a strong attraction between $\eta$ and a deuteron. The possibilities of using coherent $\pi^0\eta$ photoproduction on a nucleus to study the $\eta$-nuclear interaction are also discussed., Comment: 15 pages, 9 figures

Published
2022
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2. Resonance-like structure near the $\eta d$ threshold in the $\gamma{d}${$\to$}$\pi^0\eta{d}$ reaction

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Iwata, T., Kaida, S., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Obara, Y., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H. Y.

Subjects
Nuclear Experiment
Abstract

To investigate the interaction between the nucleon $N$ and nucleon resonance $N(1535)1/2^-$, the $\eta d$ threshold structure connected to the isoscalar $S$-wave $N$-$N(1535)1/2^-$ system has been experimentally studied in the $\gamma{d}${$\to$}$\pi^0\eta{d}$ reaction at incident photon energies ranging from the reaction threshold to 1.15 GeV. A strong enhancement is observed near the $\eta d$ threshold over the three-body phase-space contribution in the $\eta d$ invariant-mass distribution. An analysis incorporating the known isovector resonance $\mathcal{D}_{12}$ with a spin-parity of $2^+$ in the $\pi^0d$ channel reveals the existence of a narrow isoscalar resonance-like structure with $1^-$ in the $\eta d$ system. Using a Flatt\'e parametrization, the mass is found to be $2.427_{-0.006}^{+0.013}$ GeV, close to the $\eta d$ threshold, and the width is $\left(0.029_{-0.029}^{+0.006}{\rm\ GeV}\right)+\left(0.00_{-0.00}^{+0.41}\right) p_\eta c$, where $p_\eta$ denotes the $\eta$ momentum in the rest frame of the $\eta d$ system. The observed structure would be attributed to a predicted isoscalar $1^-$ $\eta NN$ bound state from $\eta NN$ and $\pi NN$ coupled-channel calculation, or an $\eta d$ virtual state owing to strong $\eta d$ attraction., Comment: 6 pages, 3 figures

Published
2021
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3. $\omega N$ scattering length from $\omega$ photoproduction on the proton near the threshold

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Hosaka, A., Iwata, T., Kaida, S., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nakamura, S. X., Nawa, K., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Sato, T., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H. Y.

Subjects
Nuclear Experiment
Abstract

Photoproduction of the $\omega$ meson on the proton has been experimentally studied near the threshold. The total cross sections are determined at incident energies ranging from 1.09 to 1.15 GeV. The 1/2 and 3/2 spin-averaged scattering length $a_{\omega p}$ and effective range $r_{\omega p}$ between the $\omega$ meson and proton are estimated from the shape of the total cross section as a function of the incident photon energy: $a_{\omega p} = \left(-0.97^{+0.16_{\rm stat}}_{-0.16_{\rm stat}}{}^{+0.03_{\rm syst}}_{-0.00_{\rm syst}}\right)+i \left(0.07^{+0.15_{\rm stat}}_{-0.14_{\rm stat}}{}^{+0.17_{\rm syst}}_{-0.09_{\rm syst}}\right)$ fm and $r_{\omega p}=\left(+2.78^{+0.68_{\rm stat}}_{-0.54_{\rm stat}}{}^{+0.11_{\rm syst}}_{-0.13_{\rm syst}}\right)+i\left(-0.01^{+0.46_{\rm stat}}_{-0.50_{\rm stat}}{}^{+0.07_{\rm syst}}_{-0.00_{\rm syst}}\right)$ fm, resulting in a repulsive force. The real and imaginary parts for $a_{\omega p}$ and $r_{\omega p}$ are determined separately for the first time. A small $P$-wave contribution does not affect the obtained values., Comment: 6 pages, 4 figures

Published
2019
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4. Non-strange Dibaryon Resonances Observed in the $\gamma d\to \pi^0\pi^0 d$ Reaction

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Iwata, T., Kaida, S., Kanda, H., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H. Y.

Subjects
Nuclear Experiment, High Energy Physics - Experiment
Abstract

Coherent double neutral-pion photoproduction on the deuteron, $\gamma{d}${$\to$}$\pi^0\pi^0{d}$, has been experimentally studied at incident photon energies ranging from 0.75 to 1.15 GeV. The total cross section as a function of the $\gamma{d}$ center-of-mass energy shows resonance-like behavior, which peaks at approximately 2.47 and 2.63 GeV. The measured angular distribution of deuteron emission is rather flat, which cannot be reproduced by the kinematics of quasi-free $\pi^0\pi^0$ production with deuteron coalescence. In $\pi^0d $ invariant-mass distributions, a clear peak is observed at $2.14{\pm}0.01$ GeV$/c^2$ with a width of $0.09{\pm}0.01$ GeV$/c^2$. The spin-parity of this state is restricted to $1^+$, $2^+$ or $3^-$ from the angular distributions of the two $\pi^0$s. The present work shows strong evidence for the existence of an isovector dibaryon resonance with a mass of 2.14 GeV$/c^2$. The $2^+$ assignment is consistent with the theoretically predicted ${\cal{D}}_{12}$ state, and also with the energy dependence of the $\pi{d}$ partial-wave amplitude $^3\!P_2$ for the $\pi^{\pm}d${$\to$}$\pi^{\pm}d$ and $\pi^+d${$\to$}${pp}$ reactions., Comment: 12 pages, 6 figures

Published
2018
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5. Study of Non-strange Dibaryon Resonances Via Coherent Double Neutral-Meson Photoproduction from the Deuteron

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Iwata, T., Kaida, S., Kanda, H., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., Yoshida, H. Y., Orr, N. A., editor, Ploszajczak, M., editor, Marqués, F. M., editor, and Carbonell, J., editor

Published
2020
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6. First measurement of coherent double neutral-pion photoproduction on the deuteron at incident energies below 0.9 GeV

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Iwata, T., Kaida, S., Kanda, H., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H. Y.

Subjects
Nuclear Experiment
Abstract

The total cross sections were measured for coherent double neutral-pion photoproduction on the deuteron at incident energies below 0.9 GeV for the first time. No clear resonance-like behavior is observed in the excitation function for $W_{\gamma d}=2.38$--2.61 GeV, where the $d^*(2380)$ dibaryon resonance observed at COSY is expected to appear. The measured excitation function is consistent with the existing theoretical calculation for this reaction. The upper limit of the total cross section is found to be $0.034$~$\mu$b for the dibaryon resonance at $W_{\gamma d}=2.37$~GeV (90\% confidence level) in the $\gamma d \to \pi^0\pi^0 d$ reaction., Comment: submitted to Physics Letters B

Published
2016
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7. An event mixing technique for Bose-Einstein correlations of two pions in photoproduction around 1 GeV

Author

He, Qing-Hua, Fujimura, H., Fukasawa, H., Hashimoto, R., Honda, Y., Ishikawa, T., Iwata, T., Kaida, S., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Ogushi, S., Okada, Y., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H. Y.

Subjects
Nuclear Experiment
Abstract

We have developed an event mixing technique to observe Bose-Einstein correlations (BEC) between two identical neutral pions produced in photo-induced reactions in the non-perturbative QCD energy region. It is found that the missing-mass consistency cut and the pion-energy cut are essential for the event mixing method to effectively extract BEC observables. A Monte Carlo (MC) simulation is used to validate these constraints and confirms the efficiency of this method. Our work paves the way for similar BEC studies at lower energies where the multiplicity of emitted bosons is limited.

Published
2016
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8. Study of Non-strange Dibaryon Resonances Via Coherent Double Neutral-Meson Photoproduction from the Deuteron

Author

Ishikawa, T., primary, Fujimura, H., additional, Fukasawa, H., additional, Hashimoto, R., additional, He, Q., additional, Honda, Y., additional, Iwata, T., additional, Kaida, S., additional, Kanda, H., additional, Kawano, A., additional, Kuwasaki, S., additional, Maeda, K., additional, Masumoto, S., additional, Miyabe, M., additional, Miyahara, F., additional, Mochizuki, K., additional, Muramatsu, N., additional, Nakamura, A., additional, Nawa, K., additional, Ogushi, S., additional, Okada, Y., additional, Okamura, K., additional, Onodera, Y., additional, Ozawa, K., additional, Sakamoto, Y., additional, Sato, M., additional, Shimizu, H., additional, Sugai, H., additional, Suzuki, K., additional, Tajima, Y., additional, Takahashi, S., additional, Taniguchi, Y., additional, Tsuchikawa, Y., additional, Yamazaki, H., additional, Yamazaki, R., additional, and Yoshida, H. Y., additional

Published
2020
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11. The FOREST detector for meson photoproduction experiments at ELPH

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., Ishida, T., Kaida, S., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Miyahara, F., Mochizuki, K., Nakabayashi, T., Nakamura, A., Nawa, K., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Saito, Y., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Takahashi, S., Tsuchikawa, Y., Yamazaki, H., and Yonemura, H.

Published
2016
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12. A fast profile monitor with scintillating fiber hodoscopes for high-intensity photon beams

Author

Ishikawa, T., Fujimura, H., Hamano, H., Hashimoto, R., Honda, Y., Ishida, T., Kaida, S., Kanda, H., Kido, S., Matsumura, Y., Miyabe, M., Mizutani, K., Nagasawa, I., Nakamura, A., Nanbu, K., Nawa, K., Ogushi, S., Shibasaki, Y., Shimizu, H., Sugai, H., Suzuki, K., Takahashi, K., Takahashi, S., Taniguchi, Y., Tokiyasu, A.O., Tsuchikawa, Y., and Yamazaki, H.

Published
2016
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16. MRI-detectable polymeric micelles incorporating platinum anticancer drugs enhance survival in an advanced hepatocellular carcinoma model

Author

Vinh NQ, Naka S, Cabral H, Murayama H, Kaida S, Kataoka K, Morikawa S, and Tani T

Subjects
Medicine (General), R5-920
Abstract

Nguyen Quoc Vinh,1 Shigeyuki Naka,1 Horacio Cabral,2 Hiroyuki Murayama,1 Sachiko Kaida,1 Kazunori Kataoka,2 Shigehiro Morikawa,3 Tohru Tani4 1Department of Surgery, Shiga University of Medical Science, Shiga, Japan; 2Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan; 3Department of Nursing, Shiga University of Medical Science, Shiga, Japan; 4Biomedical Innovation Center, Shiga University of Medical Science, Shiga, Japan Abstract: Hepatocellular carcinoma (HCC) is one of the most intractable and lethal cancers; most cases are diagnosed at advanced stages with underlying liver dysfunction and are frequently resistant to conventional chemotherapy and radiotherapy. The development of tumor-targeting systems may improve treatment outcomes. Nanomedicine platforms are of particular interest for enhancing chemotherapeutic efficiency, and they include polymeric micelles, which enable targeting of multiple drugs to solid tumors, including imaging and therapeutic agents. This allows concurrent diagnosis, targeting strategy validation, and efficacy assessment. We used polymeric micelles containing the T1-weighted magnetic resonance imaging contrast agent gadolinium-diethylenetriaminpentaacetic acid (Gd-DTPA) and the parent complex of the anticancer drug oxaliplatin [(1,2-diaminocyclohexane)platinum(II) (DACHPt)] for simultaneous imaging and therapy in an orthotopic rat model of HCC. The Gd-DTPA/DACHPt-loaded micelles were injected into the hepatic artery, and magnetic resonance imaging performance and antitumor activity against HCC, as well as adverse drug reactions were assessed. After a single administration, the micelles achieved strong and specific tumor contrast enhancement, induced high levels of tumor apoptosis, and significantly suppressed tumor size and growth. Moreover, the micelles did not induce severe adverse reactions and significantly improved survival outcomes in comparison to oxaliplatin or saline controls. Our results suggest that Gd-DTPA/DACHPt-loaded micelles are a promising approach for effective diagnosis and treatment of advanced HCC. Keywords: Gd-DTPA/DACHPt-loaded micelles, polymeric micelles, drug delivery, hepatocellular carcinoma

Published
2015

17. Coherent neutral pion and eta meson photoproduction on the deuteron

Author

Ishikawa, Takatsugu, primary, Fujimura, H., additional, Fukasawa, H., additional, Hashimoto, R., additional, He, Q., additional, Honda, Y., additional, Kaida, S., additional, Kasagi, J., additional, Kuwasaki, S., additional, Miyabe, M., additional, Miyahara, F., additional, Mochizuki, K., additional, Muramatsu, N., additional, Nakamura, A., additional, Nawa, K., additional, Ogushi, S., additional, Okada, Y., additional, Okamura, K., additional, Onodera, Y., additional, Sato, M., additional, Shimizu, H., additional, Sugai, H., additional, Suzuki, K., additional, Takahashi, S., additional, Taniguchi, Y., additional, Tsuchikawa, Y., additional, Yamazaki, H., additional, Yamazaki, R., additional, Iwata, T., additional, Tajima, Y., additional, Yoshida, H. Y., additional, Kawano, A., additional, Sakamoto, Y., additional, Maeda, K., additional, Masumoto, S., additional, Obara, Y., additional, and Ozawa, K., additional

Published
2022
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18. Coherent photoproduction of the neutral-pion and η -meson on the deuteron at incident energies below 1.15 GeV

Author

Ishikawa, T., primary, Fix, A., additional, Fujimura, H., additional, Fukasawa, H., additional, Hashimoto, R., additional, He, Q., additional, Honda, Y., additional, Iwata, T., additional, Kaida, S., additional, Kasagi, J., additional, Kawano, A., additional, Kuwasaki, S., additional, Maeda, K., additional, Masumoto, S., additional, Miyabe, M., additional, Miyahara, F., additional, Mochizuki, K., additional, Muramatsu, N., additional, Nakamura, A., additional, Nawa, K., additional, Obara, Y., additional, Ogushi, S., additional, Okada, Y., additional, Okamura, K., additional, Onodera, Y., additional, Ozawa, K., additional, Sakamoto, Y., additional, Sato, M., additional, Shimizu, H., additional, Sugai, H., additional, Suzuki, K., additional, Tajima, Y., additional, Takahashi, S., additional, Taniguchi, Y., additional, Tsuchikawa, Y., additional, Yamazaki, H., additional, Yamazaki, R., additional, and Yoshida, H. Y., additional

Published
2022
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19. Resonance-like structure near the ηd threshold in the γd→π0ηd reaction

Author

Ishikawa, T., primary, Fujimura, H., additional, Fukasawa, H., additional, Hashimoto, R., additional, He, Q., additional, Honda, Y., additional, Iwata, T., additional, Kaida, S., additional, Kasagi, J., additional, Kawano, A., additional, Kuwasaki, S., additional, Maeda, K., additional, Masumoto, S., additional, Miyabe, M., additional, Miyahara, F., additional, Mochizuki, K., additional, Muramatsu, N., additional, Nakamura, A., additional, Nawa, K., additional, Obara, Y., additional, Ogushi, S., additional, Okada, Y., additional, Okamura, K., additional, Onodera, Y., additional, Ozawa, K., additional, Sakamoto, Y., additional, Sato, M., additional, Shimizu, H., additional, Sugai, H., additional, Suzuki, K., additional, Tajima, Y., additional, Takahashi, S., additional, Taniguchi, Y., additional, Tsuchikawa, Y., additional, Yamazaki, H., additional, Yamazaki, R., additional, and Yoshida, H. Y., additional

Published
2021
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20. Study for the ω–N Interaction Through ω Photoproduction Near the Threshold

Author

Hashimoto, R., Fujimura, H., Fukasawa, H., He, Q. H., Honda, Y., Ishikawa, T., Iwata, T., Kaida, S., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Ogushi, S., Okada, Y., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H. Y.

Published
2013
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21. π 0 and η Photoproduction on the Deuteron at ELPH, Tohoku University

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Iwata, T., Kaida, S., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Ogushi, S., Okada, Y., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H. Y.

Published
2013
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22. Resonance-like structure near the $��d$ threshold in the $��{d}${$\to$}$��^0��{d}$ reaction

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Iwata, T., Kaida, S., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Obara, Y., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H. Y.

Subjects
FOS: Physical sciences, High Energy Physics::Experiment, Nuclear Experiment (nucl-ex)
Abstract

To investigate the interaction between the nucleon $N$ and nucleon resonance $N(1535)1/2^-$, the $��d$ threshold structure connected to the isoscalar $S$-wave $N$-$N(1535)1/2^-$ system has been experimentally studied in the $��{d}${$\to$}$��^0��{d}$ reaction at incident photon energies ranging from the reaction threshold to 1.15 GeV. A strong enhancement is observed near the $��d$ threshold over the three-body phase-space contribution in the $��d$ invariant-mass distribution. An analysis incorporating the known isovector resonance $\mathcal{D}_{12}$ with a spin-parity of $2^+$ in the $��^0d$ channel reveals the existence of a narrow isoscalar resonance-like structure with $1^-$ in the $��d$ system. Using a Flatt�� parametrization, the mass is found to be $2.427_{-0.006}^{+0.013}$ GeV, close to the $��d$ threshold, and the width is $\left(0.029_{-0.029}^{+0.006}{\rm\ GeV}\right)+\left(0.00_{-0.00}^{+0.41}\right) p_��c$, where $p_��$ denotes the $��$ momentum in the rest frame of the $��d$ system. The observed structure would be attributed to a predicted isoscalar $1^-$ $��NN$ bound state from $��NN$ and $��NN$ coupled-channel calculation, or an $��d$ virtual state owing to strong $��d$ attraction., 6 pages, 3 figures

Published
2021
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23. Double neutral pion photoproduction off the proton with FOREST at ELPH

Author

He Q., Fujimura H., Fukasawa H., Hashimoto R., Honda Y., Ishikawa T., Iwata T., Kaida S., Kasagi J., Kawano A., Kuwasaki S., Maeda K., Masumoto S., Miyabe M., Miyahara F., Mochizuki K., Muramatsu N., Nakamura A., Nawa K., Ogushi S., Okada Y., Onodera Y., Ozawa K., Sakamoto Y., Sato M., Shimizu H., Sugai H., Suzuki K., Tajima Y., Takahashi S., Taniguchi Y., Tsuchikawa Y., Yamazaki H., Yamazaki R., and Yoshida H. Y.

Subjects
Physics, QC1-999
Abstract

Total cross section for the double neutral pion photoproduction off the proton is presented in the incident photon energy range of 0.58 to 1.15 GeV. The data were accumulated in the years 2009–2010, recorded by a 4π EM calorimeter at ELPH, named FOREST. The number of recorded events obtained during this period is 1.6×109 for a hydrogen target. Two neutral pions are reconstructed via detecting their decay products, four gammas (2π0 → 4γ). Compared to the previous results obtained by other groups, our data are in good agreement with theirs within error bars.

Published
2016
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24. ωN scattering length from ω photoproduction on the proton near the threshold

Author

Ishikawa, T., primary, Fujimura, H., additional, Fukasawa, H., additional, Hashimoto, R., additional, He, Q., additional, Honda, Y., additional, Hosaka, A., additional, Iwata, T., additional, Kaida, S., additional, Kasagi, J., additional, Kawano, A., additional, Kuwasaki, S., additional, Maeda, K., additional, Masumoto, S., additional, Miyabe, M., additional, Miyahara, F., additional, Mochizuki, K., additional, Muramatsu, N., additional, Nakamura, A., additional, Nakamura, S. X., additional, Nawa, K., additional, Ogushi, S., additional, Okada, Y., additional, Okamura, K., additional, Onodera, Y., additional, Ozawa, K., additional, Sakamoto, Y., additional, Sato, M., additional, Sato, T., additional, Shimizu, H., additional, Sugai, H., additional, Suzuki, K., additional, Tajima, Y., additional, Takahashi, S., additional, Taniguchi, Y., additional, Tsuchikawa, Y., additional, Yamazaki, H., additional, Yamazaki, R., additional, and Yoshida, H. Y., additional

Published
2021
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26. Non-strange dibaryons studied in the γd → π0π0d reaction

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Iwata, T., Kaida, S., Kanda, H., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H.Y.

Published
2019
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27. ωN scattering length from ω photoproduction on the proton near the reaction threshold

Author

Ishikawa, T., primary, Fujimura, H., additional, Fukasawa, H., additional, Hashimoto, R., additional, He, Q., additional, Honda, Y., additional, Hosaka, A., additional, Iwata, T., additional, Kaida, S., additional, Kasagi, J., additional, Kawano, A., additional, Kuwasaki, S., additional, Maeda, K., additional, Masumoto, S., additional, Miyabe, M., additional, Miyahara, F., additional, Mochizuki, K., additional, Muramatsu, N., additional, Nakamura, A., additional, Nakamura, S. X., additional, Nawa, K., additional, Ogushi, S., additional, Okada, Y., additional, Okamura, K., additional, Onodera, Y., additional, Ozawa, K., additional, Sakamoto, Y., additional, Sato, M., additional, Sato, T., additional, Shimizu, H., additional, Sugai, H., additional, Suzuki, K., additional, Tajima, Y., additional, Takahashi, S., additional, Taniguchi, Y., additional, Tsuchikawa, Y., additional, Yamazaki, H., additional, Yamazaki, R., additional, and Yoshida, H. Y., additional

Published
2020
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28. Non-strange Dibaryons Studied in Coherent Double Neutral-meson Photoproduction on the Deuteron

Author

Ishikawa, T., primary, Fujimura, H., additional, Fukasawa, H., additional, Hashimoto, R., additional, He, Q., additional, Honda, Y., additional, Iwata, T., additional, Kaida, S., additional, Kanda, H., additional, Kasagi, J., additional, Kawano, A., additional, Kuwasaki, S., additional, Maeda, K., additional, Masumoto, S., additional, Miyabe, M., additional, Miyahara, F., additional, Mochizuki, K., additional, Muramatsu, N., additional, Nakamura, A., additional, Nawa, K., additional, Ogushi, S., additional, Okada, Y., additional, Onodera, Y., additional, Ozawa, K., additional, Sakamoto, Y., additional, Sato, M., additional, Shimizu, H., additional, Sugai, H., additional, Suzuki, K., additional, Tajima, Y., additional, Takahashi, S., additional, Taniguchi, Y., additional, Tsuchikawa, Y., additional, Yamazaki, H., additional, Yamazaki, R., additional, and Yoshida, H.Y., additional

Published
2020
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29. $\eta N$ Scattering Parameters and Possible $\eta 'd$ Bound State from $\eta $ Photoproduction on the Deuteron

Author

Ishikawa, T., primary, Aoki, K., additional, Fujimura, H., additional, Fukasawa, H., additional, Fujioka, H., additional, Hashimoto, R., additional, He, Q., additional, Honda, Y., additional, Hotta, T., additional, Inoue, Y., additional, Itahashi, K., additional, Iwata, T., additional, Kaida, S., additional, Kanda, H., additional, Kasagi, J., additional, Kawano, A., additional, Kusawaki, S., additional, Kawai, H., additional, Maeda, K., additional, Masumoto, S., additional, Matsumura, Y., additional, Miyabe, M., additional, Miyahara, F., additional, Mochizuki, K., additional, Miyata, S., additional, Muramatsu, N., additional, Nakamura, A., additional, Nawa, K., additional, Nishi, T., additional, Ohgushi, S., additional, Okada, Y., additional, Ohnishi, H., additional, Onodera, Y., additional, Ozawa, K., additional, Sakamoto, Y., additional, Sato, M., additional, Shimizu, H., additional, Sugai, H., additional, Suzuki, K., additional, Shirai, R., additional, Tabata, M., additional, Tajima, Y., additional, Takahashi, S., additional, Taniguchi, Y., additional, Tokiyasu, A.O., additional, Tsuchikawa, Y., additional, Yamazaki, H., additional, Yamazaki, R., additional, Yoshida, C., additional, and Yoshida, H.Y., additional

Published
2020
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30. Non-strange dibaryons studied in the → Reaction

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Iwata, T., Kaida, S., Kanda, H., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H.Y.

Abstract

Coherent double neutral-pion photoproduction on the deuteron, γd→π0π0d, has been experimentally studied at incident photon energies ranging from 0.75 to 1.15 GeV. The total cross section as a function of the γd center-of-mass energy shows resonance-like behavior, which peaks at approximately 2.47 and 2.63 GeV. The measured angular distribution of deuteron emission is rather flat, which cannot be reproduced by the kinematics of quasi-free π0π0 production with deuteron coalescence. In π0d invariant-mass distributions, a clear peak is observed at 2.14±0.01 GeV/c2 with a width of 0.09±0.01 GeV/c2. The spin-parity of this state is restricted to 1+, 2+ or 3− from the angular distributions of the two π0s. The present work shows strong evidence for the existence of an isovector dibaryon resonance with a mass of 2.14 GeV/c2. The 2+ assignment is consistent with the theoretically predicted D12 state, and also with the energy dependence of the πd partial-wave amplitude P23 for the π±d→π±d and π+d→pp reactions.

Published
2019

31. $��N$ scattering length from $��$ photoproduction on the proton near the threshold

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Hosaka, A., Iwata, T., Kaida, S., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nakamura, S. X., Nawa, K., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Sato, T., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H. Y.

Subjects
FOS: Physical sciences, Nuclear Experiment (nucl-ex)
Abstract

Photoproduction of the $��$ meson on the proton has been experimentally studied near the threshold. The total cross sections are determined at incident energies ranging from 1.09 to 1.15 GeV. The 1/2 and 3/2 spin-averaged scattering length $a_{��p}$ and effective range $r_{��p}$ between the $��$ meson and proton are estimated from the shape of the total cross section as a function of the incident photon energy: $a_{��p} = \left(-0.97^{+0.16_{\rm stat}}_{-0.16_{\rm stat}}{}^{+0.03_{\rm syst}}_{-0.00_{\rm syst}}\right)+i \left(0.07^{+0.15_{\rm stat}}_{-0.14_{\rm stat}}{}^{+0.17_{\rm syst}}_{-0.09_{\rm syst}}\right)$ fm and $r_{��p}=\left(+2.78^{+0.68_{\rm stat}}_{-0.54_{\rm stat}}{}^{+0.11_{\rm syst}}_{-0.13_{\rm syst}}\right)+i\left(-0.01^{+0.46_{\rm stat}}_{-0.50_{\rm stat}}{}^{+0.07_{\rm syst}}_{-0.00_{\rm syst}}\right)$ fm, resulting in a repulsive force. The real and imaginary parts for $a_{��p}$ and $r_{��p}$ are determined separately for the first time. A small $P$-wave contribution does not affect the obtained values., 6 pages, 4 figures

Published
2019
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33. ωN scattering length from ω photoproduction on the proton near the threshold.

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Hosaka, A., Iwata, T., Kaida, S., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., and Nakamura, S. X.

Subjects
PROTONS, PHOTONS, MESONS
Abstract

Photoproduction of the ω meson on the proton has been experimentally studied near the threshold. The total cross sections are determined at incident energies ranging from 1.09 to 1.15 GeV. The 1/2 and 3/2 spin-averaged scattering length aωp and effective range rωp between the ω meson and proton are estimated from the shape of the total cross section as a function of the incident photon energy: aωp=(−0.97±0.16)+ i (0.07±0.15) fm and rωp=(+2.78±0.61)+ i (−0.01±0.48) fm, which suggests a repulsive force. The real and imaginary parts for aωp and rωp are determined separately for the first time. The details of the analysis and discussions are described in Ref. [1]. [ABSTRACT FROM AUTHOR]

Published
2020
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34. Non-strange Dibaryon Resonances Observed in the $��d\to ��^0��^0 d$ Reaction

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Iwata, T., Kaida, S., Kanda, H., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Takahashi, S., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H. Y.

Subjects
High Energy Physics - Experiment (hep-ex), Nuclear Theory, FOS: Physical sciences, Nuclear Experiment (nucl-ex), Nuclear Experiment
Abstract

Coherent double neutral-pion photoproduction on the deuteron, $��{d}${$\to$}$��^0��^0{d}$, has been experimentally studied at incident photon energies ranging from 0.75 to 1.15 GeV. The total cross section as a function of the $��{d}$ center-of-mass energy shows resonance-like behavior, which peaks at approximately 2.47 and 2.63 GeV. The measured angular distribution of deuteron emission is rather flat, which cannot be reproduced by the kinematics of quasi-free $��^0��^0$ production with deuteron coalescence. In $��^0d $ invariant-mass distributions, a clear peak is observed at $2.14{\pm}0.01$ GeV$/c^2$ with a width of $0.09{\pm}0.01$ GeV$/c^2$. The spin-parity of this state is restricted to $1^+$, $2^+$ or $3^-$ from the angular distributions of the two $��^0$s. The present work shows strong evidence for the existence of an isovector dibaryon resonance with a mass of 2.14 GeV$/c^2$. The $2^+$ assignment is consistent with the theoretically predicted ${\cal{D}}_{12}$ state, and also with the energy dependence of the $��{d}$ partial-wave amplitude $^3\!P_2$ for the $��^{\pm}d${$\to$}$��^{\pm}d$ and $��^+d${$\to$}${pp}$ reactions., 12 pages, 6 figures

Published
2018
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35. First measurement of coherent double neutral-pion photoproduction on the deuteron at incident energies below 0.9 GeV

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Iwata, T., Kaida, S., Kanda, H., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., Ogushi, S., Okada, Y., Okamura, K., Onodera, Y., Ozawa, K., Sakamoto, Y., Sato, M., Shimizu, H., Sugai, H., Suzuki, K., Tajima, Y., Taniguchi, Y., Tsuchikawa, Y., Yamazaki, H., Yamazaki, R., and Yoshida, H.Y.

Published
2017
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36. ηN SCATTERING PARAMETERS AND POSSIBLE η'd BOUND STATE FROM η PHOTOPRODUCTION ON THE DEUTERON.

Author

ISHIKAWA, T., AOKI, K., FUJIMURA, H., FUKASAWA, H., FUJIOKA, H., HASHIMOTO, R., HE, Q., HONDA, Y., HOTTA, T., INOUE, Y., ITAHASHI, K., IWATA, T., KAIDA, S., KANDA, H., KASAGI, J., KAWANO, A., KUSAWAKI, S., KAWAI, H., MAEDA, K., and MASUMOTO, S.

Subjects
DEUTERONS, DIFFERENTIAL cross sections, BOUND states, MESONS, NUCLEON-nucleon interactions, PARTICLES (Nuclear physics)
Abstract

Two physics programs, determination of low-energy scattering parameters between the eta meson (η) and nucleon (N), and search for a possible bound state between the eta prime meson (η') and deuteron, using η photo-production from the deuteron target are conducted at the Research Center for Electron Photon Science (ELPH), Tohoku University. Among the twobody dynamics of the meson-nucleon systems, the ηN interaction is not well-known although it has been found attractive. An experiment is carried out to determine the low-energy ηN scattering parameters using a special kinematics. The energy and momentum of the emitted proton (p) are measured at 0 degrees for η photoproduction on the deuteron (d) at incident energies around 0.94 GeV, which gives the low relative momentum between η and neutron (n) in the final state. Low-energy ηn scattering is likely to take place in this condition, and the scattering parameters can be determined from the differential cross section as a function of the ηn invariant mass. The measurement is currently in progress to determine the real part of the ηn scattering length. A possible η'd bound state is theoretically predicted, and a structure corresponding to the state can be observed via the γd → ηd reaction at incident energies around 1.2 GeV. In the case of backward η emission, the structure becomes prominent because a background contribution coming from quasi-free single-step η emission is highly suppressed. The γd → ηd reaction has been also studied at ELPH below the incident energy of 1.15 GeV. The angular differential cross sections are determined at backward η emission angles. The tail of the corresponding peak is not observed, and the background level is much higher than predicted. [ABSTRACT FROM AUTHOR]

Published
2020
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37. Comparative evaluation of total phenolics, total flavonoids and antioxidant capacity of dried shrimp and fermented shrimp products

Author

Kaida, S. T., Rahmat, A., Ramli, Nurul Shazini, Kaida, S. T., Rahmat, A., and Ramli, Nurul Shazini

Abstract

The planktonic shrimp (Acetes indicus) is known as ‘geragau’ by local people in Malaysia. The fermented shrimp products, ‘belacan’ (shrimp paste) and ‘cincalok’ (fermented shrimp sauce) have attracted considerable attention due to their delicacy. The present work aimed to compare total phenolic content, total flavonoid content and antioxidant capacity of dried shrimp and its fermented products, ‘belacan’ and ‘cincalok’. Total phenolic (TPC) and flavanoid content (TFC) were determined using Folin-ciocalteu and aluminium trichloride colorimetric method respectively. Antioxidant capacity were determined using beta-carotene bleaching method and 2,2-diphenyl-1-picylhydrazyl (DPPH) radical scavenging assay. Results showed that fermented shrimp products (‘belacan’ and ‘cincalok’) had higher TPC content (p<0.05) compared to dried shrimp. However, ‘cincalok’ had the highest TFC and antioxidant capacity followed by ‘belacan’ and dried shrimp (p<0.05). The present study suggested that fermented shrimp products exhibited excellent antioxidant capacity compared to dried shrimp which might be due the preservation of the bioactive compounds and/or production of new antioxidant compounds during the fermentation process of ‘belacan’ and ‘cincalok’.

Published
2017

38. An event mixing technique for Bose-Einstein correlations of two pions in photoproduction around 1 GeV

Author

He, Qing-Hua, primary, Fujimura, H., additional, Fukasawa, H., additional, Hashimoto, R., additional, Honda, Y., additional, Ishikawa, T., additional, Iwata, T., additional, Kaida, S., additional, Kasagi, J., additional, Kawano, A., additional, Kuwasaki, S., additional, Maeda, K., additional, Masumoto, S., additional, Miyabe, M., additional, Miyahara, F., additional, Mochizuki, K., additional, Muramatsu, N., additional, Nakamura, A., additional, Nawa, K., additional, Ogushi, S., additional, Okada, Y., additional, Onodera, Y., additional, Ozawa, K., additional, Sakamoto, Y., additional, Sato, M., additional, Shimizu, H., additional, Sugai, H., additional, Suzuki, K., additional, Tajima, Y., additional, Takahashi, S., additional, Taniguchi, Y., additional, Tsuchikawa, Y., additional, Yamazaki, H., additional, Yamazaki, R., additional, and Yoshida, H. Y., additional

Published
2016
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39. Near Threshold K0Λ Photoproduciton on the Neutron Studied with an Electromagnetic Calorimeter FOREST

Author

Tsuchikawa, Y., primary, Fujimura, H., additional, Fukasawa, H., additional, Hashimoto, R., additional, He, Q., additional, Honda, Y., additional, Ishikawa, T., additional, Iwata, T., additional, Kaida, S., additional, Kasagi, J., additional, Kawano, A., additional, Kuwasaki, S., additional, Maeda, K., additional, Masumoto, S., additional, Miyabe, M., additional, Miyahara, F., additional, Mochizuki, K., additional, Muramatsu, N., additional, Nakamura, A., additional, Nawa, K., additional, Ogushi, S., additional, Okada, Y., additional, Onodera, Y., additional, Ozawa, K., additional, Sakamoto, Y., additional, Sato, M., additional, Shimizu, H., additional, Sugai, H., additional, Suzuki, K., additional, Tajima, Y., additional, Takahashi, S., additional, Taniguchi, Y., additional, Yamazaki, H., additional, Yamazaki, R., additional, and Yoshida, H. Y., additional

Published
2016
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40. Fasting gastric pH of Japanese subjects stratified by IgG concentration against Helicobacter pylori and pepsinogen status

Author

Kishikawa, H, Nishida, J, Ichikawa, H, Kaida, S, Takarabe, S, Matsukubo, T, Miura, S, Morishita, T, and Hibi, T

Subjects
Adult, Aged, 80 and over, Male, Gastric Juice, Helicobacter pylori, Fasting, Hydrogen-Ion Concentration, Middle Aged, Antibodies, Bacterial, Endoscopy, Gastrointestinal, Helicobacter Infections, Asian People, Gastric Mucosa, Immunoglobulin G, Pepsinogen A, Humans, Female, Atrophy, Early Detection of Cancer, Aged
Abstract

The clinical significance of Helicobacter pylori antibody titer has been controversial, and the association between the extent of gastric atrophy or acid secretion and H. pylori antibody concentration has not been elucidated.Serum pepsinogen, H. pylori antibody concentration, and fasting gastric pH (as an indicator of acid secretion) were measured in 231 patients undergoing upper gastrointestinal endoscopy. "Atrophic" pepsinogen was defined as pepsinogen-I70 ng/mL and pepsinogen-I/II ratio3. Other levels of pepsinogen were defined as "normal". Fasting gastric pH was analyzed in subjects stratified by pepsinogen level and by H. pylori antibody concentration.Helicobacter pylori antibody concentration showed no significant relationship with fasting gastric pH when all subjects were analyzed together. In H. pylori-seronegative subjects, fasting gastric pH was within the normal range, irrespective of the extent of mucosal atrophy. In H. pylori-seropositive subjects, H. pylori antibody concentration was positively correlated with fasting gastric pH in subjects with "normal" pepsinogen, but inversely correlated in those with "atrophic" pepsinogen. Particularly in subjects with low H. pylori antibody concentration and atrophic mucosa, a group reportedly at high risk of noncardia cancer, the most impaired acid secretion was shown among subjects with atrophic mucosa. The relationship between acid secretion and H. pylori antibody concentration differs depending on the presence of mucosal atrophy. Our findings provide a possible rationalization for measuring both serum pepsinogen levels and H. pylori antibody concentration in gastric cancer screening.

Published
2011

42. A detailed test of a BSO calorimeter with 100–800 MeV positrons

Author

Ishikawa, T., primary, Fujimura, H., additional, Hashimoto, R., additional, Kaida, S., additional, Kasagi, J., additional, Kitazawa, R., additional, Kuwasaki, S., additional, Nakamura, A., additional, Nawa, K., additional, Okada, Y., additional, Sato, M., additional, Shimizu, H., additional, Suzuki, K., additional, Tajima, Y., additional, Takahashi, S., additional, Tsuchikawa, Y., additional, Yamazaki, H., additional, and Yoshida, H.Y., additional

Published
2012
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46. π and η Photoproduction on the Deuteron at ELPH, Tohoku University.

Author

Ishikawa, T., Fujimura, H., Fukasawa, H., Hashimoto, R., He, Q., Honda, Y., Iwata, T., Kaida, S., Kasagi, J., Kawano, A., Kuwasaki, S., Maeda, K., Masumoto, S., Miyabe, M., Miyahara, F., Mochizuki, K., Muramatsu, N., Nakamura, A., Nawa, K., and Ogushi, S.

Subjects
DEUTERONS, BARYON spectra, QUANTUM chromodynamics, PHYSICS experiments, ELECTROMAGNETISM, NUCLEAR cross sections
Abstract

Baryon spectroscopy is important to understand Quantum Chromodynamics at low energies. In this purpose, a series of π and η photoproduction experiments was carried out with an electro-magnetic calorimeter FOREST at Research Center for Electron Photon Science, Tohoku University. The incident tagged bremsstrahlung photon energy ranges from 550 to 1,150 MeV. The differential and total cross sections obtained for π and η photoproduction processes on the proton are consistent with the SAID and MAID calculations. The analysis of π and η photoproduction on the neutron is underway. [ABSTRACT FROM AUTHOR]

Published
2013
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47. Safety, tolerability, and exposure of ciclesonide nasal spray in healthy and asymptomatic subjects with seasonal allergic rhinitis.

Author

Nave R, Wingertzahn MA, Brookman S, Kaida S, and Matsunaga T

Abstract

Ciclesonide is an intranasal corticosteroid in development for the treatment of allergic rhinitis. To assess the safety, tolerability, and pharmacokinetics of ciclesonide, adult healthy volunteers and asymptomatic subjects with seasonal allergic rhinitis were randomized to receive intranasal ciclesonide or placebo for 14 days. Serum concentrations of ciclesonide and its active metabolite, desisobutyryl-ciclesonide, were measured using high-performance liquid chromatography assay with tandem mass spectrometric detection, with lower limits of quantification of 25 and 10 pg/mL, respectively. Adrenal function was monitored by diurnal serum free and 24-hour urine cortisol concentrations. Despite the use of a sensitive assay and a high ciclesonide dose (800 microg/d), serum levels of ciclesonide and desisobutyryl-ciclesonide were below the lower limits of quantification for the majority of samples assayed. Ciclesonide was well tolerated and did not appear to affect serum or urine free cortisol levels. The low systemic exposure and favorable safety profile support the continued clinical development of ciclesonide nasal spray. [ABSTRACT FROM AUTHOR]

Published
2006

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