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Data Availability: Findings from the study will be disseminated at national and international conferences. All baseline data generated or analysed during this study are included in this published article. Electronic supplementary material is available online at https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-023-03173-7#Sec51 . Copyright © The Author(s) 2023. Background: Physical activity and emotional self-management has the potential to enhance health-related quality of life (HRQoL), but few people with chronic kidney disease (CKD) have access to resources and support. The Kidney BEAM trial aims to evaluate whether an evidence-based physical activity and emotional wellbeing self-management programme (Kidney BEAM) leads to improvements in HRQoL in people with CKD. Methods: This was a prospective, multicentre, randomised waitlist-controlled trial, with health economic analysis and nested qualitative studies. In total, three hundred and four adults with established CKD were recruited from 11 UK kidney units. Participants were randomly assigned to the intervention (Kidney BEAM) or a wait list control group (1:1). The primary outcome was the between-group difference in Kidney Disease Quality of Life (KDQoL) mental component summary score (MCS) at 12 weeks. Secondary outcomes included the KDQoL physical component summary score, kidney-specific scores, fatigue, life participation, depression and anxiety, physical function, clinical chemistry, healthcare utilisation and harms. All outcomes were measured at baseline and 12 weeks, with long-term HRQoL and adherence also collected at six months follow-up. A nested qualitative study explored experience and impact of using Kidney BEAM. Results: 340 participants were randomised to Kidney BEAM (n = 173) and waiting list (n = 167) groups. There were 96 (55%) and 89 (53%) males in the intervention and waiting list groups respectively, and the mean (SD) age was 53 (14) years in both groups. Ethnicity, body mass, CKD stage, and history of diabetes and hypertension were comparable across groups. The mean (SD) of the MCS was similar in both groups, 44.7 (10.8) and 45.9 (10.6) in the intervention and waiting list groups respectively. Conclusion: Results from this trial will establish whether the Kidney BEAM self management programme is a cost-effective method of enhancing mental and physical wellbeing of people with CKD. Trial Registration: NCT04872933. Registered 5th May 2021. This study was funded by a grant from Kidney Research UK. Funding for Kidney Beam is currently supported by the four major UK charities: Kidney Research UK, Kidney Care UK, National Kidney Federation and UK Kidney Association. HMLY is funded by the NIHR [NIHR302926].

Introduction Monitoring Health Related Quality of Life (HRQoL) in different stages of chronic kidney disease is advised by all nephrology societies. We aimed to study the relation between quality of life and dialysis adequacy. Methods One hundred patients (51% males), on regular hemodialysis 3/week for > 6 months in two hospitals were included. Single pool Kt/V was used to assess dialysis adequacy. Patients were grouped into 3 divisions according to Kt/v: Group A > 1.5 (n = 24), group B 1.2–1.5 (n = 54) and group C n = 22). KDQOL-SF™ questionnaire was used to study quality of life in our groups. Group C was reassessed after 3 months of improving Kt/v. Results Mean values were: Kt/V (1.48 ± 0.41), Cognitive Function (84.27 ± 9.96), Work status (30.00 ± 33.33), Energy (45.70 ± 13.89), Physical Function and Role limitations due to physical function (45.30 ± 12.39 and 31.25 ± 19.26, respectively). Group A had significantly higher scores of KDQOL-SF except Role limitations due to Physical Function. All subscales improved in group C after Kt/v improvement except 3 subscales, namely, work status, patient satisfaction and role limitation due to physical and emotional functions. Conclusion Inadequate HD badly affects quality of life and improving adequacy refines many components of quality of life.

AIM: To assess changes in quality of life (QL) and cognitive functions in patients with end-stage renal failure (ESRF) treated with hemodialysis using a succinate-containing dialyzing solution (SCDS)/MATERIAL AND METHODS: Sixty-seven patients with ESRF on hemodialysis using SCDS were examined. The investigators determined QL indicators using a Russianized variant of the Kidney Disease Quality of Life Short Form (KDQOL-SF) and the indicators of cognitive functions by the Benton visual retention test intended to evaluate visual short-term memory. The 6-minute walk test was used to evaluate exercise tolerance. The patients were examined before and 6 months after initiation of SCDS use/RESULTS: Following 6 months of SCDS treatment, the patients showed positive changes in a number of QL indicators. Their exercise capacity (p=0.03) and the quality of sleep (p=0.03), and social interaction (p=0.02) were improved. The magnitude of the complaints related to disease and treatment decreased (p=0.001). The level of patient frustration was reduced (p

Background: Chronic kidney disease is a worldwide health problem. Circumstances that caused the condition of end-stage renal failure causes a decrease in quality of life with a high mortality rate ranging from 22% per year. Many ways to assess the quality of life, form-36 (SF-36) has undergone several revisions refi nement. Serum ferritin continues to be the focus of attention. Nearly half of all hemodialysis patients had serum ferritin > 500 ng/ml. Serum ferritin is a marker of infl ammation that is a good, low levels correlated with iron defi ciency and high levels correlated with infl ammation.Objective: To determine the correlation of high levels of serum ferritin to decline in the quality of life in patients with CRF who had been undergoing hemodialysisMethods: This study was a cross sectional study to determine whether high levels of serum ferritin may have an impact on the decline in the quality of life in patients with chronic renal failure (CRF) who had undergone regular hemodialysis. The study was conducted at Hospital Hemodialysis Unit Dr. Sardjito,Yogyakarta. Result: A total of 61 patients who met the inclusion criteria to undergo research. Score KDQOL-SF in this study, negative correlations (weak) significant in sleep (sleep disorders) 58.79 ± 1.95 (r = -0.306) and (p = 0.017). On the Role Physical scores (physical activity) 24.59 ± 3.21 obtained a negative correlation (weak) signifi cant (r = -0.268) and (p = 0.037). For Emotional Well Being scores (emotional condition) 70.85 ± 1.39 (r = -0.374) and (p = 0.003). On the score of Energy Fatigue (physical fatigue) 62.29 ± 1.61 (r = -0.261) and (p = 0.043).Conclusion: Overall, this study shows the lack of statistically signifi cant results showed a high correlation ferritin directly on quality of life.Keywords: chronic renal failure, hemodialysis, ferritin, KDQOL-SF

We retrospectively evaluated demographic and biochemical parameters associated with depression and health-related quality of life (HRQOL) in maintenance peritoneal dialysis (PD) patients. This study included 105 patients maintaining PD at Seoul National University Hospital. Data were collected from electronic medical record. Korean Beck's Depression Inventory and Korean version of Kidney Disease Quality of Life short form, version 1.3 were used to evaluate depression and HRQOL, respectively. Moderate to severe depression was found in 24.8% of patients. Patients with lower normalized protein equivalent of nitrogen appearance (nPNA) (< 1.2 g/kg/day), lower weekly renal Kt/Vurea (< 0.2), and lower serum albumin level (≤ 4.0 g/dL) were associated with depression (P < 0.05). Among them, lower weekly renal Kt/Vurea was the only independent risk factor associated with depression (OR = 3.1, P = 0.007). Depressed patients showed significantly lower scores in every dimension of HRQOL (P < 0.001). Lower weekly renal Kt/Vurea (β = 0.24, P = 0.005) and lower nPNA (β = 0.15, P = 0.03) were the independent risk factors associated with lower kidney dialysis component summary, whereas lower plasma hemoglobin level was the consistent risk factor for lower physical component summary (β = 0.22, P = 0.03) and mental component summary (β = 0.22, P = 0.01). Depression is a prevalent psychological problem in PD population. Residual renal function is the most important factor associated with depression and impaired HRQOL in PD patients.

Filiació URV: SIInclòs a la memòria: SITítol en castellà: [Valoración de la calidad de vida relacionada con la salud en la enfermedad renal crónica terminal mediante un cuestionario de resultados percibidos por los pacientes] Objective: Evaluate the health-related quality of life for patiens with end-stage renal disease and identify the most significant differences depending on gender and treatment received. Methods and Materials: Observational, analytical and cross-sectional study (second semester 2014) carried out on patiens having high-flux hemodialysis or On-line hemodiafiltration treatment. We did descriptive and inferential statistics and the results with signification grades equal or less than 5% (p

Background Little is known how health related quality of life (HRQOL) change in the transition from dialysis to renal transplantation (RTX). Longitudinal data addressing the patient-related outcomes are scarce, and particularly data regarding kidney-specific HRQOL are lacking. Thus, the aim of the current study was to assess HRQOL in patients followed from dialysis to RTX. Furthermore, to compare HRQOL in RTX patients and the general population. Methods In a prospective study, HRQOL was measured in a cohort of 110 patients (median age 53.5 (IQR 39–62) years, GFR 54 (45–72) ml/min/1.73 m2) in dialysis and after RTX using the self-administered Kidney Disease and Quality of Life Short Form version 1.3 (KDQOL-SF). Generic HRQOL in the RTX patients was compared to that of the general population (n = 5903) using the SF-36. Clinical important change after RTX was defined as difference in HRQOL of SD/2. Results Follow-up time was 55 (IQR 50–59) months, and time after RTX was 41 (34–51) months. Four of nine domains in kidney-specific HRQOL improved after RTX, i.e. burden of kidney disease, effect of kidney disease, symptoms and work status. In SF-36, general health, vitality, social function and role physical improved after RTX, but none of the domains improved sufficiently to be regarded as clinically relevant change. There were highly significant differences in HRQOL between RTX patients and the general population after adjustment for age and gender for all items of SF-36 except for bodily pain and mental health. Conclusions HRQOL improved in the transition from dialysis to transplantation, but clinical relevant change was only obtained in the kidney specific domains. HRQOL was perceived considerably poorer in RTX patients than in the general population. Our observations point to the need of improving HRQOL even after RTX, and should encourage further longitudinal research and clinical attention during treatment shift.

ΣΚΟΠΟΣ: Η αξιολόγηση της ποιότητας ζωής ασθενών που υποβάλλονται σε χρόνια περιοδική αιμοκάθαρση στα νότια προάστια της Αττικής και η διερεύνηση του βαθμού στον οποίο ορισμένοι διαφορετικοί δημογραφικοί και κλινικοί παράγοντες επιδρούν στις διάφορες διαστάσεις της. ΥΛΙΚΟ-ΜΕΘΟΔΟΣ: Για τη μέτρηση της ποιότητας ζωής των ασθενών επιλέχθηκε δείγμα 71 ατόμων από τους αιμοκαθαιρόμενους ασθενείς ιδιωτικού νεφρολογικού κέντρου. Η ποιότητα ζωής μετρήθηκε με τη χρήση του εξειδικευμένου εργαλείου για νεφροπαθείς, KDQOL-SFTM Τα ερωτηματολόγια συμπληρώθηκαν, είτε με τη μέθοδο της προσωπικής συνέντευξης είτε με ιδιόχειρη συμπλήρωση, τον Ιούλιο του 2014. ΑΠΟΤΕΛΕΣΜΑΤΑ: Όταν χορηγήθηκε το ερωτηματολόγιο, μόλις το 14% των ασθενών του δείγματος εργαζόταν, ενώ από τις κλίμακες του KDQOL-SFTM χαμηλότερες τιμές καταγράφηκαν στην εργασία, στο φόρτο της νεφροπάθειας, στο σωματικό ρόλο, στη γενική υγεία και στη σωματική λειτουργικότητα. Η σύγκριση των κλιμάκων του SF-36 του δείγματος με τον Ελληνικό γενικό πληθυσμό παρουσίασε στατιστικά σημαντικές διαφορές (p, OBJECTIVE: Evaluate the health - related quality of life in patients on chronic periodic hemodialysis in the southern suburbs of Athens and explore the impact of some different demographic and clinical factors on its’ dimensions. METHOD: In order to measure the quality of life of patients, a sample of 71 individuals from a private dialysis center was selected. Health-related quality of life was measured using the specialized tool for renal disease, KDQOL-SFTM. The questionnaires were completed, either by personal interview or hand filling, in July 2014. RESULTS: When the questionnaire was administered, only 14% of the patients were working. The scales of the KDQOL-SF™ with the lowest prices recorded were: working status, burden of kidney disease, physical role, general health and physical functioning. The comparison of the sample’s scales of SF-36 with the Greek general population showed statistically significant differences (p

Made available in DSpace on 2016-03-22T17:27:11Z (GMT). No. of bitstreams: 1 roberta.pdf: 549584 bytes, checksum: 578a2ebea42126a08e5dde83cea1bd93 (MD5) Previous issue date: 2012-06-06 Objective: Evaluate the quality of life of patients with chronic kidney disease on hemodialysis and identify possible associations with clinical and sociodemographic variables. Method: Cross-sectional study with 68 patients with chronic renal disease on hemodialysis at the Hospital Universitário São Francisco de Paula, in Pelotas, RS. For quality of life evaluation, two instruments were used: a generic (WHOQOL-bref) and a specific (KDQOL-SF). Results: From the studied patients, 56% were men, 53% were older than 60 years and 62% had no steady partner. The mean time on hemodialysis was 26.7 months and median 14.5 months. The physical and psychological domains were more affected when compared to social and environmental domains, which had more satisfactory results (WHOQOL-bref). Concerning to the dimensions of the KDQOL-SF, the areas that obtained the highest scores were: hemodialysis staff encouragement, symptoms / problems, quality of social interaction, cognitive function and social support. The dimensions that presented more prejudice were associated with the professional role, burden of kidney disease, emotional function and general health perception. Conclusion: The patients with chronic kidney disease in hemodialysis during the treatment have significant changes in their quality of life. The knowledge of the most affected areas by the disease may assist in defining ways of serving and promoting the wellbeing of patient Objetivo: Avaliar a qualidade de vida de pacientes renais crônicos em hemodiálise e identificar possíveis associações com variáveis clínicas e sociodemográficas. Método: Estudo transversal realizado com 68 pacientes portadores de doença renal crônica, submetidos à hemodiálise no Hospital Universitário São Francisco de Paula, na cidade de Pelotas, RS. Para avaliação da qualidade de vida foram utilizados dois instrumentos; um genérico (WHOQOL-Abreviado) e outro específico (KDQOL-SF). Resultados: Dos pacientes incluídos no estudo, 56% eram homens, 53% tinham idade superior a 60 anos, e 62% não tinham companheiro fixo. O tempo médio em hemodiálise foi 26,7 meses e mediana 14,5 meses. Os domínios físico e psicológico se mostraram mais comprometidos quando comparados aos domínios social e ambiental, que tiveram resultados mais satisfatórios (WHOQOL-abreviado). Quanto às dimensões do KDQOL-SF, as áreas que obtiveram as maiores pontuações foram estímulo por parte da equipe, sintomas/problemas, qualidade da interação social, função cognitiva e suporte social. As dimensões que apresentaram mais prejuízo estiveram associadas ao papel profissional, sobrecarga da doença renal, função emocional e percepção da saúde geral. Conclusão: O portador de Insuficiência Renal Crônica em vigência do tratamento de hemodiálise tem alterações significativas em sua qualidade de vida. O conhecimento das áreas mais comprometidas pela doença poderá auxiliar na definição de melhores formas de atendimento e promoção do bem-estar do paciente

RESUMO INTRODUÇÃO: Qualidade de vida é uma dimensão que tem sido amplamente investigada na saúde da população, independente da faixa etária. Uma condição crônica é um fator que interfere na realização das atividades da vida diária e na percepção de bem-estar individual, como é o caso dos pacientes em tratamento por hemodiálise. OBJETIVO: Descrever as características e analisar as possíveis associações entre a Insuficiência Renal Crônica (IRC) e a qualidade de vida em uma amostra representativa de pacientes com o agravo no município de Caruaru, PE. MÉTODO: A pesquisa foi realizada nos centros de tratamentos dialíticos na cidade de Caruaru, onde toda a população com IRC é atendida (n = 192), sendo 82 pacientes do Centro Regional de Hemodiálise do Agreste (CRHA) e 110 da clínica SOS Rim - Clínica Nefrológica de Caruaru. Para a composição da amostra foi realizado um censo e todos os pacientes cadastrados foram pré-selecionados inicialmente para o estudo. RESULTADOS: Verificou-se que a maioria dos participantes relatou algum grau de incômodo: dores musculares (69,4%), cãibras (89,8%), coceiras (67,3%), fraqueza muscular (73,5%), diminuição de líquido (91,8%), diminuição alimentar (85,7%) e capacidade de trabalhar (75,5%). Já quando questionados se o esforço físico interfere na sua qualidade de vida, este estudo revelou que 70,3% afirmam que sim. Em relação à saúde, 80,6% das pessoas dizem que a doença renal crônica interfere de forma negativa na qualidade de vida. CONCLUSÃO: Os dados indicam que pacientes com IRC apresentam diminuição na qualidade de vida graças a repercussões musculoesqueléticas, tais como cãibras, fraqueza muscular e esforço físico. INTRODUCTION: Life quality has been a subject of growing research in studies of population health, in all times of ages. A chronic condition is a factor that interferes with the conduct of activities of daily living and the perception of individual well-being, as is the case of patients being treated by hemodialysis. OBJECTIVE: To describe the characteristics and to analyze the possible associations between the CRF and life quality related to health in a representative sample of patients which was worsted in the city of Caruaru, PE. METHOD: The survey was conducted in dialysis treatment centers in Caruaru city, where all population with CRF is attended (n = 192), being 82 patients of the Regional Hemodialysis Center (Centro Regional de Hemodiálise do Agreste - CRHA) and 110 patients of the SOS Rim Clinic - Caruaru's Nephrological Clinical. For the composition of the sample was accomplished a census and all patients enrolled were initially preselected first for study. RESULTS: It was verified that the majority of study participants reported some degree of discomfort: muscle pain (69.4%), cramps (89.8%), itching (67.3%), weakness (73.5%), reduced net (91.8%), decreased food (85.7%) and ability to work (75.5%). When asked if the physical effort interferes with their quality of life, this study revealed that 70.3% say so. In relation to health, 80.6% of people say that kidney disease interferes in a negative way on the quality of life. CONCLUSION: The data in this study indicate that patients with CRF have decreased in life quality due to musculoskeletal repercussions such as cramps, muscle weakness and physical effort.

Este artigo pretende descrever e comparar a qualidade de vida relacionada com a saúde nas pessoas com insuficiência renal crónica em diálise de acordo com os diferentes tipos de admissão. Foi desenvolvido um estudo não experimental, transversal e descritivo numa amostra de 231 pessoas com insuficiência renal crónica, conforme o tipo de admissão à diálise e que efectuavam tratamento dialítico no nordeste transmontano. Utilizou-se o instrumento de medição KDQOL constituído por uma medida genérica de saúde - o SF-36 - e uma específica deste quadro clínico - o ESRD. Dos participantes estudados, a maioria era do sexo masculino (56,3%), casados (68,4%), reformados ou pensionistas (84,9%), provenientes de zona rural (67,4%) e com um nível de instrução básico ou inferior (89,1%). A idade dos respondentes variou entre os 18 e os 88 anos, com uma média de 61,6 anos e uma mediana de 65 anos. O tempo de diálise destes doentes foi entre 15 dias e 24 anos e o tipo de tratamento mais prevalente foi a hemodiálise (94,8%). A maior parte dos doentes apresentou outras doenças associadas (56,3%) e complicações (91%), tendo sido a diabetes a doença associada mais referida (26,4%) e o cansaço (69,7%), as mãos e pés adormecidos (58,9%), as cãibras (54,5%), as dores musculares (52,4%) e a comichão (51,5%), as complicações mais assinaladas. Os doentes com admissão programada para diálise apresentaram uma qualidade de vida mais satisfatória do que os admitidos de forma urgente, com diferenças estatisticamente significativas na actividade profissional, no desempenho físico, no desempenho emocional, na função social e na vitalidade. Os resultados evidenciaram também um impacto negativo de algumas variáveis sócio-demográficas e clínicas. Nesta investigação é reconhecida a importância da avaliação da qualidade de vida relacionada com a saúde, como um indicador de excelência dos cuidados de saúde, reflectindo a voz do utente.

Texto completo: acesso restrito. p. 545-557 Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-01-24T15:50:32Z No. of bitstreams: 1 art%3A10.1007%2Fs11136-006-9143-7.pdf: 191775 bytes, checksum: bca7bf4b36e1915b707d6bf08f97eb3d (MD5) Approved for entry into archive by Solange Gomes (soldella@ufba.br) on 2014-08-11T19:18:19Z (GMT) No. of bitstreams: 1 art%3A10.1007%2Fs11136-006-9143-7.pdf: 191775 bytes, checksum: bca7bf4b36e1915b707d6bf08f97eb3d (MD5) Made available in DSpace on 2014-08-11T19:18:19Z (GMT). No. of bitstreams: 1 art%3A10.1007%2Fs11136-006-9143-7.pdf: 191775 bytes, checksum: bca7bf4b36e1915b707d6bf08f97eb3d (MD5) Previous issue date: 2007 Objective: To identify modifiable factors associated with health-related quality of life (HRQOL) among chronic hemodialysis patients. Methods: Analysis of baseline data of 9,526 hemodialysis patients from seven countries enrolled in phase I of the Dialysis Outcomes and Practice Patterns Study (DOPPS). Using the Kidney Disease Quality of Life Short Form (KDQOL-SFTM), we determined scores for 8 generic scale summaries derived from these scales, i.e., the physical component summary [PCS] and mental component summary [MCS], and 11 kidney disease-targeted scales. Regression models were used to adjust for differences in comorbidities and sociodemographic and treatment factors. The Benjamin-Hochberg procedure was used to correct P-values for multiple comparisons. Results: Unemployment and psychiatric disease were independently and significantly associated with lower scores for all generic and several kidney disease-targeted HRQOL measures. Several other comorbidities, lower educational level, lower income, and hypoalbuminemia were also independently and significantly associated with lower scores of PCS and/or MCS and several generic and kidney disease-targeted scales. Hemodialysis by catheter was associated with significantly lower PCS scores, partially explained by the correlation with covariates. Conclusion: Associations of poorer HRQOL with preventable or controllable factors support a greater focus on psychosocial and medical interventions to improve the well-being of hemodialysis patients.

Texto completo: acesso restrito. p. 545-557 Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-01-24T15:50:32Z No. of bitstreams: 1 art%3A10.1007%2Fs11136-006-9143-7.pdf: 191775 bytes, checksum: bca7bf4b36e1915b707d6bf08f97eb3d (MD5) Approved for entry into archive by Solange Gomes (soldella@ufba.br) on 2014-08-11T19:18:19Z (GMT) No. of bitstreams: 1 art%3A10.1007%2Fs11136-006-9143-7.pdf: 191775 bytes, checksum: bca7bf4b36e1915b707d6bf08f97eb3d (MD5) Made available in DSpace on 2014-08-11T19:18:19Z (GMT). No. of bitstreams: 1 art%3A10.1007%2Fs11136-006-9143-7.pdf: 191775 bytes, checksum: bca7bf4b36e1915b707d6bf08f97eb3d (MD5) Previous issue date: 2007 Objective: To identify modifiable factors associated with health-related quality of life (HRQOL) among chronic hemodialysis patients. Methods: Analysis of baseline data of 9,526 hemodialysis patients from seven countries enrolled in phase I of the Dialysis Outcomes and Practice Patterns Study (DOPPS). Using the Kidney Disease Quality of Life Short Form (KDQOL-SFTM), we determined scores for 8 generic scale summaries derived from these scales, i.e., the physical component summary [PCS] and mental component summary [MCS], and 11 kidney disease-targeted scales. Regression models were used to adjust for differences in comorbidities and sociodemographic and treatment factors. The Benjamin-Hochberg procedure was used to correct P-values for multiple comparisons. Results: Unemployment and psychiatric disease were independently and significantly associated with lower scores for all generic and several kidney disease-targeted HRQOL measures. Several other comorbidities, lower educational level, lower income, and hypoalbuminemia were also independently and significantly associated with lower scores of PCS and/or MCS and several generic and kidney disease-targeted scales. Hemodialysis by catheter was associated with significantly lower PCS scores, partially explained by the correlation with covariates. Conclusion: Associations of poorer HRQOL with preventable or controllable factors support a greater focus on psychosocial and medical interventions to improve the well-being of hemodialysis patients.

The objective of the present study was to translate the Kidney Disease Quality of Life - Short Form (KDQOL-SF 1.3) questionnaire into Portuguese to adapt it culturally and validate it for the Brazilian population. The KDQOL-SF was translated into Portuguese and back-translated twice into English. Patient difficulties in understanding the questionnaire were evaluated by a panel of experts and solved. Measurement properties such as reliability and validity were determined by applying the questionnaire to 94 end-stage renal disease patients on chronic dialysis. The Nottingham Health Profile Questionnaire, the Karnofsky Performance Scale and the Kidney Disease Questionnaire were administered to test validity. Some activities included in the original instrument were considered to be incompatible with the activities usually performed by the Brazilian population and were replaced. The mean scores for the 19 components of the KDQOL-SF questionnaire in Portuguese ranged from 22 to 91. The components Social support and Dialysis staff encouragement had the highest scores (86.7 and 90.8, respectively). The test-retest reliability and the inter-observer reliability of the instrument were evaluated by the intraclass correlation coefficient. The coefficients for both reliability tests were statistically significant for all scales of the KDQOL-SF (P < 0.001), ranging from 0.492 to 0.936 for test-retest reliability and from 0.337 to 0.994 for inter-observer reliability. The Cronbach's alpha coefficient was higher than 0.80 for most of components. The Portuguese version of the KDQOL-SF questionnaire proved to be valid and reliable for the evaluation of quality of life of Brazilian patients with end-stage renal disease on chronic dialysis. Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de Medicina UNIFESP, EPM, Depto. de Medicina SciELO

The objective of the present study was to translate the Kidney Disease Quality of Life - Short Form (KDQOL-SF™1.3) questionnaire into Portuguese to adapt it culturally and validate it for the Brazilian population. The KDQOL-SF was translated into Portuguese and back-translated twice into English. Patient difficulties in understanding the questionnaire were evaluated by a panel of experts and solved. Measurement properties such as reliability and validity were determined by applying the questionnaire to 94 end-stage renal disease patients on chronic dialysis. The Nottingham Health Profile Questionnaire, the Karnofsky Performance Scale and the Kidney Disease Questionnaire were administered to test validity. Some activities included in the original instrument were considered to be incompatible with the activities usually performed by the Brazilian population and were replaced. The mean scores for the 19 components of the KDQOL-SF questionnaire in Portuguese ranged from 22 to 91. The components "Social support" and "Dialysis staff encouragement" had the highest scores (86.7 and 90.8, respectively). The test-retest reliability and the inter-observer reliability of the instrument were evaluated by the intraclass correlation coefficient. The coefficients for both reliability tests were statistically significant for all scales of the KDQOL-SF (P < 0.001), ranging from 0.492 to 0.936 for test-retest reliability and from 0.337 to 0.994 for inter-observer reliability. The Cronbach's alpha coefficient was higher than 0.80 for most of components. The Portuguese version of the KDQOL-SF questionnaire proved to be valid and reliable for the evaluation of quality of life of Brazilian patients with end-stage renal disease on chronic dialysis.

OBJETIVO: Realizar a tradução para o português e a adaptação cultural do instrumento Kidney Disease Quality of Life Short Form - KDQOL-SF TM para sua posterior validação no Brasil. MÉTODOS: O instrumento foi traduzido da versão original (Inglês) para a língua portuguesa pelos autores e por tradutor juramentado e, posteriormente, revisado e avaliado quanto ao grau de dificuldade das traduções e equivalência por tradutor especialista. O instrumento foi, então, aplicado em 30 pacientes com insuficiência renal crônica terminal, em tratamento dialítico, selecionados aleatoriamente. RESULTADOS: A idade média dos pacientes foi 47±9 anos (variação, 23 a 60 anos), com escolaridade básica incompleta em 53% deles, sendo 60% do sexo feminino. A maioria dos pacientes (63%) realizava hemodiálise e o período de tratamento nos 30 dias antecedentes à aplicação do questionário foi de pelo menos 12 horas ou mais por semana. O tempo de tratamento dialítico era de 0-2 anos para 70% dos pacientes. A viabilidade do instrumento e as dificuldades encontradas pelos pacientes foram avaliadas por um painel de profissionais e as mudanças foram feitas baseadas nas dificuldades de compreensão. As atividades do instrumento original incompatíveis com atividades realizadas habitualmente pela população brasileira foram substituídas. Foram modificadas expressões da tradução, por termos sugeridos pelos pacientes e especialistas brasileiros e a explicação de cinco itens foi colocada entre parênteses para facilitar a compreensão. As palavras de uso comum da língua portuguesa foram mantidas. CONCLUSÃO: A tradução e a adaptação cultural do questionário KDQOL-SF para o português foram realizadas, tendo sido cumprida esta importante etapa para sua validação e utilização em nosso meio. BACKGROUND: The objective of this study was to translate from English into Portuguese and to perform cultural adaptation of the Kidney Disease Quality of Life Short Form - KDQOL-SF TM to make possible its validation in Brazil. METHODS: This instrument was translated from the original English version into Portuguese language by the authors and it was also translated by a certified translator and revised by a specialized translator who evaluated the level of difficulty for translation. Thirty end-stage renal disease patients undergoing dialysis were randomly selected to participate in the study. RESULTS: The mean age of patients was 47±9 years (23 to 60 yr), and the predominant education level was incomplete elementary school (1st to 8th grade=53%); 60% of the patients were female. The majority of patients (63%) were undergoing hemodialysis and the period of treatment within the last 30 days was 12 hours or more per week. The time of dialysis treatment was 0-2 years for 70% of the patients. The feasibility of the instrument and the difficulties found by the patients were evaluated by a panel of experts and changes were made regarding difficulties of comprehension. Some activities were substituted since they were not regular for the Brazilian population. There were modifications in expressions of translation for terms suggested by patients and Brazilian experts and, for five items it was suggested to include an explanation in parentheses. Common words used in the Portuguese language were chosen. CONCLUSIONS: The translation and cross-cultural adaptation of the KDQOL questionnaire to Portuguese were concluded, having been accomplished this important stage for its validation and use in our environment.

Filiació URV: SIInclòs a la memòria: SITítol en castellà: [Valoración de la calidad de vida relacionada con la salud en la enfermedad renal crónica terminal mediante un cuestionario de resultados percibidos por los pacientes] Objective: Evaluate the health-related quality of life for patiens with end-stage renal disease and identify the most significant differences depending on gender and treatment received. Methods and Materials: Observational, analytical and cross-sectional study (second semester 2014) carried out on patiens having high-flux hemodialysis or On-line hemodiafiltration treatment. We did descriptive and inferential statistics and the results with signification grades equal or less than 5% (p

RESUMO INTRODUÇÃO: Qualidade de vida é uma dimensão que tem sido amplamente investigada na saúde da população, independente da faixa etária. Uma condição crônica é um fator que interfere na realização das atividades da vida diária e na percepção de bem-estar individual, como é o caso dos pacientes em tratamento por hemodiálise. OBJETIVO: Descrever as características e analisar as possíveis associações entre a Insuficiência Renal Crônica (IRC) e a qualidade de vida em uma amostra representativa de pacientes com o agravo no município de Caruaru, PE. MÉTODO: A pesquisa foi realizada nos centros de tratamentos dialíticos na cidade de Caruaru, onde toda a população com IRC é atendida (n = 192), sendo 82 pacientes do Centro Regional de Hemodiálise do Agreste (CRHA) e 110 da clínica SOS Rim - Clínica Nefrológica de Caruaru. Para a composição da amostra foi realizado um censo e todos os pacientes cadastrados foram pré-selecionados inicialmente para o estudo. RESULTADOS: Verificou-se que a maioria dos participantes relatou algum grau de incômodo: dores musculares (69,4%), cãibras (89,8%), coceiras (67,3%), fraqueza muscular (73,5%), diminuição de líquido (91,8%), diminuição alimentar (85,7%) e capacidade de trabalhar (75,5%). Já quando questionados se o esforço físico interfere na sua qualidade de vida, este estudo revelou que 70,3% afirmam que sim. Em relação à saúde, 80,6% das pessoas dizem que a doença renal crônica interfere de forma negativa na qualidade de vida. CONCLUSÃO: Os dados indicam que pacientes com IRC apresentam diminuição na qualidade de vida graças a repercussões musculoesqueléticas, tais como cãibras, fraqueza muscular e esforço físico.