Search

Your search keyword '"KESESIDIS, NIKOLAOS"' showing total 9 results
Start Over Author "KESESIDIS, NIKOLAOS"
9 results on '"KESESIDIS, NIKOLAOS"'

4. A novel Dhillonvirus phage against Escherichia coli bearing a unique open reading frame of intergeneric origin.

Author

Vasileiadis, Anastasios, primary, Bozidis, Petros, additional, Konstantinidis, Konstantinos, additional, Kesesidis, Nikolaos, additional, Potamiti, Louiza, additional, Kolliopoulou, Anna, additional, Beloukas, Apostolos, additional, Panayiotidis, Mihalis I., additional, Gartzonika, Konstantina, additional, and Karakasiliotis, Ioannis, additional

Published
2023
Full Text
View/download PDF

5. Next-Generation Sequencing Analysis of Mutations in Circulating Tumor DNA from the Plasma of Patients with Head–Neck Cancer Undergoing Chemo-Radiotherapy Using a Pan-Cancer Cell-Free Assay

Author

Koukourakis, Michael I., primary, Xanthopoulou, Erasmia, additional, Koukourakis, Ioannis M., additional, Fortis, Sotirios P., additional, Kesesidis, Nikolaos, additional, Kakouratos, Christos, additional, Karakasiliotis, Ioannis, additional, and Baxevanis, Constantin N., additional

Published
2023
Full Text
View/download PDF

7. Emergence of Clonally-Related South Asian Clade I Clinical Isolates of Candida auris in a Greek COVID-19 Intensive Care Unit

Author

Katsiari, Maria, primary, Mavroidi, Angeliki, additional, Kesesidis, Nikolaos, additional, Palla, Eleftheria, additional, Zourla, Konstantina, additional, Ntorlis, Kyriakos, additional, Konstantinidis, Konstantinos, additional, Laskou, Maria, additional, Strigklis, Konstantinos, additional, Sakkalis, Anastasios, additional, Nikolaou, Charikleia, additional, Platsouka, Evangelia D., additional, Karakasiliotis, Ioannis, additional, Vrioni, Georgia, additional, and Tsakris, Athanasios, additional

Published
2023
Full Text
View/download PDF

8. p‐cymene impairs SARS‐CoV‐2 and Influenza A (H1N1) viral replication: In silico predicted interaction with SARS‐CoV‐2 nucleocapsid protein and H1N1 nucleoprotein

Author

Panagiotopoulos, Athanasios, primary, Tseliou, Melpomeni, additional, Karakasiliotis, Ioannis, additional, Kotzampasi, Danai‐Maria, additional, Daskalakis, Vangelis, additional, Kesesidis, Nikolaos, additional, Notas, George, additional, Lionis, Christos, additional, Kampa, Marilena, additional, Pirintsos, Stergios, additional, Sourvinos, George, additional, and Castanas, Elias, additional

Published
2021
Full Text
View/download PDF

9. Disruption of LEDGF/p75-directed integration derepresses antisense transcription of the HIV-1 genome.

Author

Tedbury PR, Mahboubi D, Puray-Chavez M, Shah R, Ukah OB, Wahoski CC, Fadel HJ, Poeschla EM, Gao X, McFadden WM, Gaitanidou M, Kesesidis N, Kirby KA, Vanderford TH, Kvaratskhelia M, Achuthan V, Behrens RT, Engelman AN, and Sarafianos SG

Abstract

Disruption of HIV-1 Integrase (IN) interactions with the host-factor Lens Epithelium-Derived Growth Factor (LEDGF)/p75 leads to decreased, random integration, increased latent infection, and described here, accumulation of HIV-1 antisense RNA (asRNA). asRNA increase was observed following interruptions of IN-LEDGF/p75 interactions either through pharmacologic perturbations of IN-LEDGF/p75 by treatment with allosteric HIV-1 integrase inhibitors (ALLINIs) or in cell lines with LEDGF genetic knockout. Additionally, by impairing Tat-dependent HIV transcription, asRNA abundance markedly increases. Illumina sequencing characterization of asRNA transcripts in primary T cells infected in the presence of ALLINIs showed that most initiate from within the HIV-1. Overall, loss of IN-LEDGF/p75 interactions increase asRNA abundance. Understanding the relationship between ALLINIs, integration sites, asRNA, and latency could aid in future therapeutic strategies., Competing Interests: Competing interests: Authors declare that they have no competing interests.

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results