1. CLINICAL AND HEMATOBIOCHEMICAL STUDY ON THE THERAPEUTIC EFFICACY OF A POLYHERBAL FORMULATION IN CATTLE AFFECTED BY LUMPY SKIN DISEASE.
- Author
-
Dhaka, Manoj Kumar, Singh, A. P., Kachhawa, J. P., Gupta, Sita Ram, and Mathur, Manisha
- Subjects
LUMPY skin disease ,BLOOD urea nitrogen ,CATTLE showing ,BLOOD diseases ,DAIRY farms ,RESPIRATION - Abstract
The proposed study was carried out on adult crossbred cattle showing classic clinical signs of Lumpy skin disease at private dairy farms as well as on animals of individual holdings in the Bikaner, Rajasthan. This was verified by clinical examinations and molecular diagnosis was preferred by PCR. The 16 cattle were selected for this experiment, which underwent clinical examinations and hematology and serum biochemistry parameters evaluation. Cattle were randomly divided into two groups, Group-II was treated with polyherbal preparation A and Group-III was treated with polyherbal preparation B. Eight healthy adult cattle were retained as the control group (Group-I). In LSD affected cattle, Major clinical manifestations were pyrexia, anorexia, emaciation, lymph node enlargement, skin nodules,lacrimation and oedema. Clinical vital parameters revealed significantly (p<0.05) higher values of rectal temperature, heart rate and respiration rate while significantly (p<0.05) decreased rumen motility. Haematological results showed significant (p<0.01) reduction in mean values of Hb, PCV, TEC, TLC and platelet count when compared to healthy cattle(Group-I). Significant neutrophilia and lymphopenia showed in DLC values, in affected cattle. Pre-treatment hypoproteinemia, hypoalbuminemia, and increased concentration of SGOT, SGPT, ALP, creatinine and blood urea nitrogen (BUN) showed by LSD affected cattle. After therapeutic management of LSD affected cattle with polyherbal formulations for 15 days in both groups, improvement towards normalcy in haemato-biochemical parameters were observed with variation in efficacies of different treatment regimens at different time intervals. Therapeutic effect of polyherbal formulations was observed in the LSD affected cattle that showed significant improvement in various clinical signs, haemato-biochemical parameters. [ABSTRACT FROM AUTHOR]
- Published
- 2024