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3. Building bridges for innovation in ageing: Synergies between action groups of the EIP on AHA

Author

Bousquet, Jean, Bewick, M., Cano, A., Eklund, P., Fico, G., Goswami, N., Guldemond, N.A., Henderson, D., Hinkema, M.J., Liotta, G., Mair, A., Molloy, W., Monaco, A., Monsonis-Paya, I., Nizinska, A., Papadopoulos, H., Pavlickova, A., Pecorelli, S., Prados-Torres, A., Roller-Wirnsberger, R.E., Somekh, D., Vera-Muñoz, C., Visser, F., Farrell, J., Malva, J., Andersen Ranberg, K., Camuzat, T., Carriazo, A.M., Crooks, G., Gutter, Z., Iaccarino, G., de Keenoy, E. Manuel, Moda, G., Rodriguez-Mañas, L., Vontetsianos, T., Abreu, C., Alonso, J., Alonso-Bouzon, C., Ankri, J., Arredondo, M.T., Avolio, F., Bedbrook, A., Białoszewski, A.Z., Blain, H., Bourret, R., Cabrera-Umpierrez, M.F., Catala, A., O'Caoimh, R., Cesari, M., Chavannes, N.H., Correia-Da-Sousa, J., Dedeu, T., Ferrando, M., Ferri, M., Fokkens, W.J., Garcia-Lizana, F., Guérin, O., Hellings, P.W., Haahtela, T., Illario, M., Inzerilli, M.C., Lodrup Carlsen, K.C., Kardas, P., Keil, T., Maggio, M., Mendez-Zorrilla, A., Menditto, E., Mercier, J., Michel, J.P., Murray, R., Nogues, M., O'Byrne-Maguire, I., Pappa, D., Parent, A.S., Pastorino, M., Robalo-Cordeiro, C., Samolinski, B., Siciliano, P., Teixeira, A.M., Tsartara, S.I., Valiulis, A., Vandenplas, O., Vasankari, T., Vellas, B., Vollenbroek-Hutten, M., Wickman, M., Yorgancioglu, A., Zuberbier, T., Barbagallo, M., Canonica, G.W., Klimek, L., Maggi, S., Aberer, W., Akdis, C., Adcock, I.M., Agache, I., Albera, C., Alonso-Trujillo, F., Angel Guarcia, M., Annesi-Maesano, I., Apostolo, J., Arshad, S.H., Attalin, V., Avignon, A., Bachert, C., Baroni, I., Bel, E., Benson, M., Bescos, C., Blasi, F., Barbara, C., Bergmann, K.C., Bernard, P.L., Bonini, S., Bousquet, P.J., Branchini, B., Brightling, C.E., Bruguière, V., Bunu, C., Bush, A., Caimmi, D.P., Calderon, M.A., Canovas, G., Cardona, V., Carlsen, K.H., Cesario, A., Chkhartishvili, E., Chiron, R., Chivato, T., Chung, K.F., D'Angelantonio, M., de Carlo, G., Cholley, D., Chorin, F., Combe, B., Compas, B., Costa, D.J., Costa, E., Coste, O., Coupet, A. -L., Crepaldi, G., Custovic, A., Dahl, R., Dahlen, S.E., Demoly, P., Devillier, P., Didier, A., Dinh-Xuan, A.T., Djukanovic, R., Dokic, D., du Toit, G., Dubakiene, R., Dupeyron, A., Emuzyte, R., Fiocchi, A., Wagner, A., Fletcher, M., Fonseca, J., Fougère, B., Gamkrelidze, A., Garces, G., Garcia-Aymeric, J., Garcia-Zapirain, B., Gemicioğlu, B., Gouder, C., Hellquist-Dahl, B., Hermosilla-Gimeno, I., Héve, D., Holland, C., Humbert, M., Hyland, M., Johnston, S.L., Just, J., Jutel, M., Kaidashev, I.P., Kaitov, M., Kalayci, O., Kalyoncu, A.F., Keijser, W., Kerstjens, H., Knezović, J., Kowalski, M., Koppelman, G.H., Kotska, T., Kovac, M., Kull, I., Kuna, P., Kvedariene, V., Lepore, V., Macnee, W., Magnan, A., Majer, I., Manning, P., Marcucci, M., Marti, T., Masoli, M., Melen, E., Miculinic, N., Mihaltan, F., Milenkovic, B., Millot-Keurinck, J., Mlinarić, H., Momas, I., Montefort, S., Morais-Almeida, M., Moreno-Casbas, T., Mösges, R., Mullol, J., Nadif, R., Nalin, M., Navarro-Pardo, E., Nekam, K., Ninot, G., Paccard, D., Pais, S., Palummeri, E., Panzner, P., Papadopoulos, N.K., Papanikolaou, C., Passalacqua, G., Pastor, E., Perrot, M., Plavec, D., Popov, T.A., Postma, D.S., Price, D., Raffort, N., Reuzeau, J.C., Robine, J.M., Rodenas, F., Robusto, F., Roche, N., Romano, A., Romano, V., Rosado-Pinto, J., Roubille, F., Ruiz, F., Ryan, D., Salcedo, T., Schmid-Grendelmeier, P., Schulz, H., Schunemann, H.J., Serrano, E., Sheikh, A., Shields, M., Siafakas, N., Scichilone, N., Skrindo, I., Smit, H.A., Sourdet, S., Sousa-Costa, E., Spranger, O., Sooronbaev, T., Sruk, V., Sterk, P.J., Todo-Bom, A., Touchon, J., Tramontano, D., Triggiani, M., Valero, A.L., Valovirta, E., van Ganse, E., van Hage, M., van den Berge, M., Ventura, M.T., Vergara, I., Vezzani, G., Vidal, D., Viegi, G., Wagemann, M., Whalley, B., Wilson, N., Yiallouros, P.K., Žagar, M., Zaidi, A., Zidarn, M., Hoogerwerf, E.J., Usero, J., Zuffada, R., Senn, A., and de Oliveira-Alves, B.

Published
2017
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9. Erratum to: Building bridges for innovation in ageing: Synergies between action groups of the EIP on AHA

Author

Bousquet, Jean, Bewick, M., Cano, A., Eklund, P., Fico, G., Goswami, N., Guldemond, N.A., Henderson, D., Hinkema, M.J., Liotta, G., Mair, A., Molloy, W., Monaco, A., Monsonis-Paya, I., Nizinska, A., Papadopoulos, H., Pavlickova, A., Pecorelli, S., Prados-Torres, A., Roller-Wirnsberger, R.E., Somekh, D., Vera-Muñoz, C., Visser, F., Farrell, J., Malva, J., Andersen Ranberg, K., Camuzat, T., Carriazo, A.M., Crooks, G., Gutter, Z., Iaccarino, G., de Keenoy, E. Manuel, Moda, G., Rodriguez-Mañas, L., Vontetsianos, T., Abreu, C., Alonso, J., Alonso-Bouzon, C., Ankri, J., Arredondo, M.T., Avolio, F., Bedbrook, A., Białoszewski, A.Z., Blain, H., Bourret, R., Cabrera-Umpierrez, M.F., Catala, A., O'Caoimh, R., Cesari, M., Chavannes, N.H., Correia-Da-Sousa, J., Dedeu, T., Ferrando, M., Ferri, M., Fokkens, W.J., Garcia-Lizana, F., Guérin, O., Hellings, P.W., Haahtela, T., Illario, M., Inzerilli, M.C., Lodrup Carlsen, K.C., Kardas, P., Keil, T., Maggio, M., Mendez-Zorrilla, A., Menditto, E., Mercier, J., Michel, J.P., Murray, R., Nogues, M., O'Byrne-Maguire, I., Pappa, D., Parent, A.S., Pastorino, M., Robalo-Cordeiro, C., Samolinski, B., Siciliano, P., Teixeira, A.M., Tsartara, S.I., Valiulis, A., Vandenplas, O., Vasankari, T., Vellas, B., Vollenbroek-Hutten, M., Wickman, M., Yorgancioglu, A., Zuberbier, T., Barbagallo, M., Canonica, G.W., Klimek, L., Maggi, S., Aberer, W., Akdis, C., Adcock, I.M., Agache, I., Albera, C., Alonso-Trujillo, F., Angel Guarcia, M., Annesi-Maesano, I., Apostolo, J., Arshad, S.H., Attalin, V., Avignon, A., Bachert, C., Baroni, I., Bel, E., Benson, M., Bescos, C., Blasi, F., Barbara, C., Bergmann, K.C., Bernard, P.L., Bonini, S., Bousquet, P.J., Branchini, B., Brightling, C.E., Bruguière, V., Bunu, C., Bush, A., Caimmi, D.P., Calderon, M.A., Canovas, G., Cardona, V., Carlsen, K.H., Cesario, A., Chkhartishvili, E., Chiron, R., Chivato, T., Chung, K.F., D'Angelantonio, M., de Carlo, G., Cholley, D., Chorin, F., Combe, B., Compas, B., Costa, D.J., Costa, E., Coste, O., Coupet, A. -L., Crepaldi, G., Custovic, A., Dahl, R., Dahlen, S.E., Demoly, P., Devillier, P., Didier, A., Dinh-Xuan, A.T., Djukanovic, R., Dokic, D., du Toit, G., Dubakiene, R., Dupeyron, A., Emuzyte, R., Fiocchi, A., Wagner, A., Fletcher, M., Fonseca, J., Fougère, B., Gamkrelidze, A., Garces, G., Garcia-Aymeric, J., Garcia-Zapirain, B., Gemicioğlu, B., Gouder, C., Hellquist-Dahl, B., Hermosilla-Gimeno, I., Héve, D., Holland, C., Humbert, M., Hyland, M., Johnston, S.L., Just, J., Jutel, M., Kaidashev, I.P., Kaitov, M., Kalayci, O., Kalyoncu, A.F., Keijser, W., Kerstjens, H., Knezović, J., Kowalski, M., Koppelman, G.H., Kotska, T., Kovac, M., Kull, I., Kuna, P., Kvedariene, V., Lepore, V., Macnee, W., Magnan, A., Majer, I., Manning, P., Marcucci, M., Marti, T., Masoli, M., Melen, E., Miculinic, N., Mihaltan, F., Milenkovic, B., Millot-Keurinck, J., Mlinarić, H., Momas, I., Montefort, S., Morais-Almeida, M., Moreno-Casbas, T., Mösges, R., Mullol, J., Nadif, R., Nalin, M., Navarro-Pardo, E., Nekam, K., Ninot, G., Paccard, D., Pais, S., Palummeri, E., Panzner, P., Papadopoulos, N.K., Papanikolaou, C., Passalacqua, G., Pastor, E., Perrot, M., Plavec, D., Popov, T.A., Postma, D.S., Price, D., Raffort, N., Reuzeau, J.C., Robine, J.M., Rodenas, F., Robusto, F., Roche, N., Romano, A., Romano, V., Rosado-Pinto, J., Roubille, F., Ruiz, F., Ryan, D., Salcedo, T., Schmid-Grendelmeier, P., Schulz, H., Schunemann, H.J., Serrano, E., Sheikh, A., Shields, M., Siafakas, N., Scichilone, N., Skrindo, I., Smit, H.A., Sourdet, S., Sousa-Costa, E., Spranger, O., Sooronbaev, T., Sruk, V., Sterk, P.J., Todo-Bom, A., Touchon, J., Tramontano, D., Triggiani, M., Valero, A.L., Valovirta, E., van Ganse, E., van Hage, M., van den Berge, M., Ventura, M.T., Vergara, I., Vezzani, G., Vidal, D., Viegi, G., Wagemann, M., Whalley, B., Wilson, N., Yiallouros, P.K., Žagar, M., Zaidi, A., Zidarn, M., Hoogerwerf, E.J., Usero, J., Zuffada, R., Senn, A., and de Oliveira-Alves, B.

Published
2023
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22. Building bridges for innovation in ageing: Synergies between action groups of the EIP on AHA

Author

Bousquet, J. Bewick, M. Cano, A. Eklund, P. Fico, G. Goswami, N. Guldemond, N.A. Henderson, D. Hinkema, M.J. Liotta, G. Mair, A. Molloy, W. Monaco, A. Monsonis-Paya, I. Nizinska, A. Papadopoulos, H. Pavlickova, A. Pecorelli, S. Prados-Torres, A. Roller-Wirnsberger, R.E. Somekh, D. Vera-Muñoz, C. Visser, F. Farrell, J. Malva, J. Andersen Ranberg, K. Camuzat, T. Carriazo, A.M. Crooks, G. Gutter, Z. Iaccarino, G. de Keenoy, E.M. Moda, G. Rodriguez-Mañas, L. Vontetsianos, T. Abreu, C. Alonso, J. Alonso-Bouzon, C. Ankri, J. Arredondo, M.T. Avolio, F. Bedbrook, A. Białoszewski, A.Z. Blain, H. Bourret, R. Cabrera-Umpierrez, M.F. Catala, A. O’Caoimh, R. Cesari, M. Chavannes, N.H. Correia-Da-Sousa, J. Dedeu, T. Ferrando, M. Ferri, M. Fokkens, W.J. Garcia-Lizana, F. Guérin, O. Hellings, P.W. Haahtela, T. Illario, M. Inzerilli, M.C. Lodrup Carlsen, K.C. Kardas, P. Keil, T. Maggio, M. Mendez-Zorrilla, A. Menditto, E. Mercier, J. Michel, J.P. Murray, R. Nogues, M. O’Byrne-Maguire, I. Pappa, D. Parent, A.S. Pastorino, M. Robalo-Cordeiro, C. Samolinski, B. Siciliano, P. Teixeira, A.M. Tsartara, S.I. Valiulis, A. Vandenplas, O. Vasankari, T. Vellas, B. Vollenbroek-Hutten, M. Wickman, M. Yorgancioglu, A. Zuberbier, T. Barbagallo, M. Canonica, G.W. Klimek, L. Maggi, S. Aberer, W. Akdis, C. Adcock, I.M. Agache, I. Albera, C. Alonso-Trujillo, F. Angel Guarcia, M. Annesi-Maesano, I. Apostolo, J. Arshad, S.H. Attalin, V. Avignon, A. Bachert, C. Baroni, I. Bel, E. Benson, M. Bescos, C. Blasi, F. Barbara, C. Bergmann, K.C. Bernard, P.L. Bonini, S. Bousquet, P.J. Branchini, B. Brightling, C.E. Bruguière, V. Bunu, C. Bush, A. Caimmi, D.P. Calderon, M.A. Canovas, G. Cardona, V. Carlsen, K.H. Cesario, A. Chkhartishvili, E. Chiron, R. Chivato, T. Chung, K.F. D’Angelantonio, M. de Carlo, G. Cholley, D. Chorin, F. Combe, B. Compas, B. Costa, D.J. Costa, E. Coste, O. Coupet, A.-L. Crepaldi, G. Custovic, A. Dahl, R. Dahlen, S.E. Demoly, P. Devillier, P. Didier, A. Dinh-Xuan, A.T. Djukanovic, R. Dokic, D. du Toit, G. Dubakiene, R. Dupeyron, A. Emuzyte, R. Fiocchi, A. Wagner, A. Fletcher, M. Fonseca, J. Fougère, B. Gamkrelidze, A. Garces, G. Garcia-Aymeric, J. Garcia-Zapirain, B. Gemicioğlu, B. Gouder, C. Hellquist-Dahl, B. Hermosilla-Gimeno, I. Héve, D. Holland, C. Humbert, M. Hyland, M. Johnston, S.L. Just, J. Jutel, M. Kaidashev, I.P. Kaitov, M. Kalayci, O. Kalyoncu, A.F. Keijser, W. Kerstjens, H. Knezović, J. Kowalski, M. Koppelman, G.H. Kotska, T. Kovac, M. Kull, I. Kuna, P. Kvedariene, V. Lepore, V. Macnee, W. Magnan, A. Majer, I. Manning, P. Marcucci, M. Marti, T. Masoli, M. Melen, E. Miculinic, N. Mihaltan, F. Milenkovic, B. Millot-Keurinck, J. Mlinarić, H. Momas, I. Montefort, S. Morais-Almeida, M. Moreno-Casbas, T. Mösges, R. Mullol, J. Nadif, R. Nalin, M. Navarro-Pardo, E. Nekam, K. Ninot, G. Paccard, D. Pais, S. Palummeri, E. Panzner, P. Papadopoulos, N.K. Papanikolaou, C. Passalacqua, G. Pastor, E. Perrot, M. Plavec, D. Popov, T.A. Postma, D.S. Price, D. Raffort, N. Reuzeau, J.C. Robine, J.M. Rodenas, F. Robusto, F. Roche, N. Romano, A. Romano, V. Rosado-Pinto, J. Roubille, F. Ruiz, F. Ryan, D. Salcedo, T. Schmid-Grendelmeier, P. Schulz, H. Schunemann, H.J. Serrano, E. Sheikh, A. Shields, M. Siafakas, N. Scichilone, N. Siciliano, P. Skrindo, I. Smit, H.A. Sourdet, S. Sousa-Costa, E. Spranger, O. Sooronbaev, T. Sruk, V. Sterk, P.J. Todo-Bom, A. Touchon, J. Tramontano, D. Triggiani, M. Valero, A.L. Valovirta, E. van Ganse, E. van Hage, M. van den Berge, M. Ventura, M.T. Vergara, I. Vezzani, G. Vidal, D. Viegi, G. Wagemann, M. Whalley, B. Wilson, N. Yiallouros, P.K. Žagar, M. Zaidi, A. Zidarn, M. Hoogerwerf, E.J. Usero, J. Zuffada, R. Senn, A. de Oliveira-Alves, B.

Abstract

The Strategic Implementation Plan of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) proposed six Action Groups. After almost three years of activity, many achievements have been obtained through commitments or collaborative work of the Action Groups. However, they have often worked in silos and, consequently, synergies between Action Groups have been proposed to strengthen the triple win of the EIP on AHA. The paper presents the methodology and current status of the Task Force on EIP on AHA synergies. Synergies are in line with the Action Groups’ new Renovated Action Plan (2016-2018) to ensure that their future objectives are coherent and fully connected. The outcomes and impact of synergies are using the Monitoring and Assessment Framework for the EIP on AHA (MAFEIP). Eight proposals for synergies have been approved by the Task Force: Five cross-cutting synergies which can be used for all current and future synergies as they consider overarching domains (appropriate polypharmacy, citizen empowerment, teaching and coaching on AHA, deployment of synergies to EU regions, Responsible Research and Innovation), and three cross-cutting synergies focussing on current Action Group activities (falls, frailty, integrated care and chronic respiratory diseases). © 2017, Serdi and Springer-Verlag France.

Published
2017

23. Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)(Clin Transl Allergy (2016) 6 (29) DOI: 10.1186/s13601-016-0116-9)

Author

Bousquet, J. Farrell, J. Crooks, G. Hellings, P. Bel, E.H. Bewick, M. Chavannes, N.H. De Sousa, J.C. Cruz, A.A. Haahtela, T. Joos, G. Khaltaev, N. Malva, J. Muraro, A. Nogues, M. Palkonen, S. Pedersen, S. Robalo-Cordeiro, C. Samolinski, B. Strandberg, T. Valiulis, A. Yorgancioglu, A. Zuberbier, T. Bedbrook, A. Aberer, W. Adachi, M. Agusti, A. Akdis, C.A. Akdis, M. Ankri, J. Alonso, A. Annesi-Maesano, I. Ansotegui, I.J. Anto, J.M. Arnavielhe, S. Arshad, H. Bai, C. Baiardini, I. Bachert, C. Baigenzhin, A.K. Barbara, C. Bateman, E.D. Beghé, B. Kheder, A.B. Bennoor, K.S. Benson, M. Bergmann, K.C. Bieber, T. Bindslev-Jensen, C. Bjermer, L. Blain, H. Blasi, F. Boner, A.L. Bonini, M. Bonini, S. Bosnic-Anticevitch, S. Boulet, L.P. Bourret, R. Bousquet, P.J. Braido, F. Briggs, A.H. Brightling, C.E. Brozek, J. Buhl, R. Burney, P.G. Bush, A. Caballero-Fonseca, F. Caimmi, D. Calderon, M.A. Calverley, P.M. Camargos, P.A.M. Canonica, G.W. Camuzat, T. Carlsen, K.H. Carr, W. Carriazo, A. Casale, T. Cepeda Sarabia, A.M. Chatzi, L. Chen, Y.Z. Chiron, R. Chkhartishvili, E. Chuchalin, A.G. Chung, K.F. Ciprandi, G. Cirule, I. Cox, L. Costa, D.J. Custovic, A. Dahl, R. Dahlen, S.E. Darsow, U. De Carlo, G. De Blay, F. Dedeu, T. Deleanu, D. De Manuel Keenoy, E. Demoly, P. Denburg, J.A. Devillier, P. Didier, A. Dinh-Xuan, A.T. Djukanovic, R. Dokic, D. Douagui, H. Dray, G. Dubakiene, R. Durham, S.R. Dykewicz, M.S. El-Gamal, Y. Emuzyte, R. Fabbri, L.M. Fletcher, M. Fiocchi, A. Fink Wagner, A. Fonseca, J. Fokkens, W.J. Forastiere, F. Frith, P. Gaga, M. Gamkrelidze, A. Garces, J. Garcia-Aymerich, J. Gemicioǧlu, B. Gereda, J.E. González Diaz, S. Gotua, M. Grisle, I. Grouse, L. Gutter, Z. Guzmán, M.A. Heaney, L.G. Hellquist-Dahl, B. Henderson, D. Hendry, A. Heinrich, J. Heve, D. Horak, F. Hourihane, J.O.B. Howarth, P. Humbert, M. Hyland, M.E. Illario, M. Ivancevich, J.C. Jardim, J.R. Jares, E.J. Jeandel, C. Jenkins, C. Johnston, S.L. Jonquet, O. Julge, K. Jung, K.S. Just, J. Kaidashev, I.P. Khaitov, M.R. Kalayci, O. Kalyoncu, A.F. Keil, T. Keith, P.K. Klimek, L. Koffi N'Goran, B. Kolek, V. Koppelman, G.H. Kowalski, M.L. Kull, I. Kuna, P. Kvedariene, V. Lambrecht, B. Lau, S. Larenas-Linnemann, D. Laune, D. Le, L.T.T. Lieberman, P. Lipworth, B. Li, J. Lodrup Carlsen, K. Louis, R. MacNee, W. Magard, Y. Magnan, A. Mahboub, B. Mair, A. Majer, I. Makela, M.J. Manning, P. Mara, S. Marshall, G.D. Masjedi, M.R. Matignon, P. Maurer, M. Mavale-Manuel, S. Melén, E. Melo-Gomes, E. Meltzer, E.O. Menzies-Gow, A. Merk, H. Michel, J.P. Miculinic, N. Mihaltan, F. Milenkovic, B. Mohammad, G.M.Y. Molimard, M. Momas, I. Montilla-Santana, A. Morais-Almeida, M. Morgan, M. Mösges, R. Mullol, J. Nafti, S. Namazova-Baranova, L. Naclerio, R. Neou, A. Neffen, H. Nekam, K. Niggemann, B. Ninot, G. Nyembue, T.D. O'Hehir, R.E. Ohta, K. Okamoto, Y. Okubo, K. Ouedraogo, S. Paggiaro, P. Pali-Schöll, I. Panzner, P. Papadopoulos, N. Papi, A. Park, H.S. Passalacqua, G. Pavord, I. Pawankar, R. Pengelly, R. Pfaar, O. Picard, R. Pigearias, B. Pin, I. Plavec, D. Poethig, D. Pohl, W. Popov, T.A. Portejoie, F. Potter, P. Postma, D. Price, D. Rabe, K.F. Raciborski, F. Radier Pontal, F. Repka-Ramirez, S. Reitamo, S. Rennard, S. Rodenas, F. Roberts, J. Roca, J. Rodriguez Mañas, L. Rolland, C. Roman Rodriguez, M. Romano, A. Rosado-Pinto, J. Rosario, N. Rosenwasser, L. Rottem, M. Ryan, D. Sanchez-Borges, M. Scadding, G.K. Schunemann, H.J. Serrano, E. Schmid-Grendelmeier, P. Schulz, H. Sheikh, A. Shields, M. Siafakas, N. Sibille, Y. Similowski, T. Simons, F.E.R. Sisul, J.C. Skrindo, I. Smit, H.A. Solé, D. Sooronbaev, T. Spranger, O. Stelmach, R. Sterk, P.J. Sunyer, J. Thijs, C. To, T. Todo-Bom, A. Triggiani, M. Valenta, R. Valero, A.L. Valia, E. Valovirta, E. Van Ganse, E. Van Hage, M. Vandenplas, O. Vasankari, T. Vellas, B. Vestbo, J. Vezzani, G. Vichyanond, P. Viegi, G. Vogelmeier, C. Vontetsianos, T. Wagenmann, M. Wallaert, B. Walker, S. Wang, D.Y. Wahn, U. Wickman, M. Williams, D.M. Williams, S. Wright, J. Yawn, B.P. Yiallouros, P.K. Yusuf, O.M. Zaidi, A. Zar, H.J. Zernotti, M.E. Zhang, L. Zhong, N. Zidarn, M. Mercier, J.

Published
2017

24. Lifestyle Change as a Part of Complex Therapy of Chronic Systemic Inflammation in Metabolic Syndrome

Author

Kaidashev, I.P.

Abstract

From a perspective of integrative physiology, metabolic syndrome (MS) can be regarded as a syntropy of internal diseases, based on the systemic inflammation, insulin resistance, lipotoxicity and other processes which depend on the activation of NF-kB. The general aspects of the systemic inflammation role in the development of MS, especially the participation of the adipose tissue in the proinflammatory cytokines production, have been observed. The data of modern clinical trials about impact of lifestyle change (increased physical activity, dietary restrictions) on the level of systemic inflammation in patients with MS have been presented. The necessity for randomized controlled clinical trials in order to determine the regimen of physical training and dietary restriction, aimed at the reduction of systemic inflammation in MS, has been concluded., С позиций интегративной физиологии метаболический синдром (МС) можно рассматривать как синтропию заболеваний внутренних органов, в основе которой лежат системное воспаление, инсулинорезистентность, липотоксичность и другие процессы, зависящие от активации ядерного фактора NF-kB. Рассмотрены общие вопросы о роли системного воспаления в развитии МС, в частности участия жировой ткани в продукции провоспалительных цитокинов. Приведены данные современных клинических исследований о влиянии изменения образа жизни (увеличение физических нагрузок, ограничение рациона) на уровень системного воспаления у лиц с МС. Сделан вывод о необходимости проведения рандомизированных контролируемых клинических исследований для определения режимов физических тренировок и ограничения рациона питания, направленных на снижение уровня системного воспаления при МС., З позицій інтегративної фізіології метаболічний синдром (МС) можна розглядати як синтропію захворювань внутрішніх органів, в основі якої лежать системне запалення, інсулінорезистентність, ліпотоксичність та інші процеси, що залежать від активації ядерного фактора NF-kB. Розглянуто загальні питання щодо ролі системного запалення в розвитку МС, зокрема участі жирової тканини в продукції прозапальних цитокінів. Наведено дані сучасних клінічних досліджень про вплив зміни способу життя (збільшення фізичних навантажень, обмеження раціону) на рівень системного запалення в осіб із МС. Зроблено висновок про необхідність проведення рандомізованих контрольованих клінічних досліджень для визначення режимів фізичних тренувань та обмеження раціону харчування, що спрямовані на зниження рівня системного запалення при МС.

Published
2012
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28. Erratum to: Building bridges for innovation in ageing: Synergies between action groups of the EIP on AHA

Author

Bousquet, J. Bewick, M. Cano, A. Eklund, P. Fico, G. Goswami, N. Guldemond, N.A. Henderson, D. Hinkema, M.J. Liotta, G. Mair, A. Molloy, W. Monaco, A. Monsonis-Paya, I. Nizinska, A. Papadopoulos, H. Pavlickova, A. Pecorelli, S. Prados-Torres, A. Roller-Wirnsberger, R.E. Somekh, D. Vera-Muñoz, C. Visser, F. Farrell, J. Malva, J. Andersen Ranberg, K. Camuzat, T. Carriazo, A.M. Crooks, G. Gutter, Z. Iaccarino, G. de Keenoy, E.M. Moda, G. Rodriguez-Mañas, L. Vontetsianos, T. Abreu, C. Alonso, J. Alonso-Bouzon, C. Ankri, J. Arredondo, M.T. Avolio, F. Bedbrook, A. Białoszewski, A.Z. Blain, H. Bourret, R. Cabrera-Umpierrez, M.F. Catala, A. O’Caoimh, R. Cesari, M. Chavannes, N.H. Correia-Da-Sousa, J. Dedeu, T. Ferrando, M. Ferri, M. Fokkens, W.J. Garcia-Lizana, F. Guérin, O. Hellings, P.W. Haahtela, T. Illario, M. Inzerilli, M.C. Lodrup Carlsen, K.C. Kardas, P. Keil, T. Maggio, M. Mendez-Zorrilla, A. Menditto, E. Mercier, J. Michel, J.P. Murray, R. Nogues, M. O’Byrne-Maguire, I. Pappa, D. Parent, A.S. Pastorino, M. Robalo-Cordeiro, C. Samolinski, B. Siciliano, P. Teixeira, A.M. Tsartara, S.I. Valiulis, A. Vandenplas, O. Vasankari, T. Vellas, B. Vollenbroek-Hutten, M. Wickman, M. Yorgancioglu, A. Zuberbier, T. Barbagallo, M. Canonica, G.W. Klimek, L. Maggi, S. Aberer, W. Akdis, C. Adcock, I.M. Agache, I. Albera, C. Alonso-Trujillo, F. Angel Guarcia, M. Annesi-Maesano, I. Apostolo, J. Arshad, S.H. Attalin, V. Avignon, A. Bachert, C. Baroni, I. Bel, E. Benson, M. Bescos, C. Blasi, F. Barbara, C. Bergmann, K.C. Bernard, P.L. Bonini, S. Bousquet, P.J. Branchini, B. Brightling, C.E. Bruguière, V. Bunu, C. Bush, A. Caimmi, D.P. Calderon, M.A. Canovas, G. Cardona, V. Carlsen, K.H. Cesario, A. Chkhartishvili, E. Chiron, R. Chivato, T. Chung, K.F. D’Angelantonio, M. de Carlo, G. Cholley, D. Chorin, F. Combe, B. Compas, B. Costa, D.J. Costa, E. Coste, O. Coupet, A.-L. Crepaldi, G. Custovic, A. Dahl, R. Dahlen, S.E. Demoly, P. Devillier, P. Didier, A. Dinh-Xuan, A.T. Djukanovic, R. Dokic, D. du Toit, G. Dubakiene, R. Dupeyron, A. Emuzyte, R. Fiocchi, A. Wagner, A. Fletcher, M. Fonseca, J. Fougère, B. Gamkrelidze, A. Garces, G. Garcia-Aymeric, J. Garcia-Zapirain, B. Gemicioğlu, B. Gouder, C. Hellquist-Dahl, B. Hermosilla-Gimeno, I. Héve, D. Holland, C. Humbert, M. Hyland, M. Johnston, S.L. Just, J. Jutel, M. Kaidashev, I.P. Khaitov, M. Kalayci, O. Kalyoncu, A.F. Keijser, W. Kerstjens, H. Knezović, J. Kowalski, M. Koppelman, G.H. Kotska, T. Kovac, M. Kull, I. Kuna, P. Kvedariene, V. Lepore, V. Macnee, W. Maggio, M. Magnan, A. Majer, I. Manning, P. Marcucci, M. Marti, T. Masoli, M. Melen, E. Miculinic, N. Mihaltan, F. Milenkovic, B. Millot-Keurinck, J. Mlinarić, H. Momas, I. Montefort, S. Morais-Almeida, M. Moreno-Casbas, T. Mösges, R. Mullol, J. Nadif, R. Nalin, M. Navarro-Pardo, E. Nekam, K. Ninot, G. Paccard, D. Pais, S. Palummeri, E. Panzner, P. Papadopoulos, N.K. Papanikolaou, C. Passalacqua, G. Pastor, E. Perrot, M. Plavec, D. Popov, T.A. Postma, D.S. Price, D. Raffort, N. Reuzeau, J.C. Robine, J.M. Rodenas, F. Robusto, F. Roche, N. Romano, A. Romano, V. Rosado-Pinto, J. Roubille, F. Ruiz, F. Ryan, D. Salcedo, T. Schmid-Grendelmeier, P. Schulz, H. Schunemann, H.J. Serrano, E. Sheikh, A. Shields, M. Siafakas, N. Scichilone, N. Siciliano, P. Skrindo, I. Smit, H.A. Sourdet, S. Sousa-Costa, E. Spranger, O. Sooronbaev, T. Sruk, V. Sterk, P.J. Todo-Bom, A. Touchon, J. Tramontano, D. Triggiani, M. Tsartara, S.I. Valero, A.L. Valovirta, E. van Ganse, E. van Hage, M. van Den Berge, M. Vandenplas, O. Ventura, M.T. Vergara, I. Vezzani, G. Vidal, D. Viegi, G. Wagemann, M. Whalley, B. Wickman, M. Wilson, N. Yiallouros, P.K. Žagar, M. Zaidi, A. Zidarn, M. Hoogerwerf, E.J. Usero, J. Zuffada, R. Senn, A. de Oliveira-Alves, B.

Abstract

The authors would like to change and use the correct name of M. Khaitov which is M. Kaitov on this manuscript. The authors have incorrectly used her other name during the finalization of this research. With this, the authors hereby publish the correct author names as presented above. © 2016 Serdi and Springer-Verlag France

Published
2016

29. MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis

Author

Bousquet, J. Schünemann, H.J. Hellings, P.W. Arnavielhe, S. Bachert, C. Bedbrook, A. Bergmann, K.-C. Bosnic-Anticevich, S. Brozek, J. Calderon, M. Canonica, G.W. Casale, T.B. Chavannes, N.H. Cox, L. Chrystyn, H. Cruz, A.A. Dahl, R. De Carlo, G. Demoly, P. Devillier, P. Dray, G. Fletcher, M. Fokkens, W.J. Fonseca, J. Gonzalez-Diaz, S.N. Grouse, L. Keil, T. Kuna, P. Larenas-Linnemann, D. Lodrup Carlsen, K.C. Meltzer, E.O. Mullol, J. Muraro, A. Naclerio, R.N. Palkonen, S. Papadopoulos, N.G. Passalacqua, G. Price, D. Ryan, D. Samolinski, B. Scadding, G.K. Sheikh, A. Spertini, F. Valiulis, A. Valovirta, E. Walker, S. Wickman, M. Yorgancioglu, A. Haahtela, T. Zuberbier, T. Aberer, W. Adachi, M. Agache, I. Akdis, C. Akdis, M. Annesi-Maesano, I. Ansotegui, I.J. Anto, J.M. Arshad, S.H. Baiardini, I. Baigenzhin, A.K. Barbara, C. Bateman, E.D. Beghé, B. Bel, E.H. Ben Kheder, A. Bennoor, K.S. Benson, M. Bernstein, D. Michael, B. Thomas, B. Bindslev-Jensen, C. Bjermer, L. Blain, H. Boner, A. Bonini, M. Bonini, S. Bosse, I. Bouchard, J. Boulet, L.-P. Bourret, R.A. Bousquet, P.J. Braido, F. Briggs, A.H. Brightling, C.E. Buhl, R. Burney, P. Bush, A. Caballero-Fonseca, F. Caimmi, D.P. Camargos, P. Camuzat, T. Carlsen, K.-H. Carr, W. Casale, T.B. Sarabia, A.C. Chatzi, L. Chen, Y. Chiron, R. Chkhartishvili, E. Chuchalin, A. Ciprandi, G. Cirule, I. Correia de Sousa, J. Costa, D. Crooks, G. Custovic, A. Dahlen, S.-E. Darsow, U. De Blay, F. De Manuel Keenoy, E. Dedeu, T. Deleanu, D. Denburg, J. Didier, A. Dinh-Xuan, A.-T. Dokic, D. Douagui, H.B. Dubakiene, R. Durham, S. Dykewicz, M. El-Gamal, Y. Emuzyte, R. Fink-Wagner, A. Fiocchi, A. Forastiere, F. Gamkrelidze, A. Gemicioğlu, B. Gereda, J.E. Gerth van Wijk, R. Gotua, M. Grisle, I. Guzmán, M.A. Haahtela, T. Heinrich, J. Hellquist-Dahl, B. Horak, F. Howarth, P.H. Humbert, M. Hyland, M. Ivancevich, J.-C. Jares, E.J. Johnston, S.L. Jonquet, O. Joos, G. Jung, K.-S. Just, J. Jutel, M. Kaidashev, I.P. Khaitov, M. Kalayci, O. Kalyoncu, F. Keith, P. Khaltaev, N. Kleine-Tebbe, J. Klimek, L. N'Goran, B.K. Kolek, V. Koppelman, G.H. Kowalski, M. Kull, I. Kvedariene, V. Lambrecht, B. Lau, S. Laune, D. Le Thi Tuyet, L. Li, J. Lieberman, P. Lipworth, B.J. Renaud, L. Magard, Y. Magnan, A. Mahboub, B. Majer, I. Makela, M. Manning, P.J. Masjedi, M.R. Maurer, M. Mavale-Manuel, S. Melén, E. Melo-Gomes, E. Mercier, J. Merk, H. Miculinic, N. Mihaltan, F. Milenkovic, B. Mohammad, Y. Molimard, M. Momas, I. Montilla-Santana, A. Morais-Almeida, M. Mösges, R. Nadif, R. Namazova-Baranova, L. Neffen, H. Nekam, K. Neou, A. Niggemann, B. Nyembue, D. O'Hehir, R. Ohta, K. Okamoto, Y. Okubo, K. Ouedraogo, S. Paggiaro, P.-L. Pali-Schöll, I. Palmer, S. Panzner, P. Papi, A. Park, H.-S. Pavord, I. Pawankar, R. Pfaar, O. Picard, R. Pigearias, B. Pin, I. Plavec, D. Pohl, W. Popov, T. Postma, D.S. Potter, P. Poulsen, L.K. Rabe, K.F. Raciborski, F. Pontal, F.R. Reitamo, S. Repka-Ramirez, M.-S. Robalo-Cordeiro, C. Roberts, G. Rodenas, F. Rolland, C. Rodriguez, M.R. Romano, A. Rosado-Pinto, J. Rosario, N.A. Rosenwasser, L. Rottem, M. Sanchez-Borges, M. Sastre-Dominguez, J. Schmid-Grendelmeier, P. Serrano, E. Simons, F.E.R. Sisul, J.-C. Skrindo, I. Smit, H.A. Solé, D. Sooronbaev, T. Spranger, O. Stelmach, R. Strandberg, T. Sunyer, J. Thijs, C. Todo-Bom, A.-M. Triggiani, M. Valenta, R. Valero, A.L. van Hage, M. Vandenplas, O. Vezzani, G. Vichyanond, P. Viegi, G. Wagenmann, M. Wahn, U. De Yun, W. Williams, D. Wright, J. Yawn, B.P. Yiallouros, P. Yusuf, O.M. Zar, H.J. Zernotti, M. Zhang, L. Zhong, N. Zidarn, M.

Abstract

The selection of pharmacotherapy for patients with allergic rhinitis (AR) depends on several factors, including age, prominent symptoms, symptom severity, control of AR, patient preferences, and cost. Allergen exposure and the resulting symptoms vary, and treatment adjustment is required. Clinical decision support systems (CDSSs) might be beneficial for the assessment of disease control. CDSSs should be based on the best evidence and algorithms to aid patients and health care professionals to jointly determine treatment and its step-up or step-down strategy depending on AR control. Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR [fighting chronic diseases for active and healthy ageing]), one of the reference sites of the European Innovation Partnership on Active and Healthy Ageing, has initiated an allergy sentinel network (the MACVIA-ARIA Sentinel Network). A CDSS is currently being developed to optimize AR control. An algorithm developed by consensus is presented in this article. This algorithm should be confirmed by appropriate trials. © 2016 The Authors

Published
2016

30. ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle

Author

Bousquet, J. Hellings, P.W. Agache, I. Bedbrook, A. Bachert, C. Bergmann, K.C. Bewick, M. Bindslev-Jensen, C. Bosnic-Anticevitch, S. Bucca, C. Caimmi, D.P. Camargos, P.A.M. Canonica, G.W. Casale, T. Chavannes, N.H. Cruz, A.A. De Carlo, G. Dahl, R. Demoly, P. Devillier, P. Fonseca, J. Fokkens, W.J. Guldemond, N.A. Haahtela, T. Illario, M. Just, J. Keil, T. Klimek, L. Kuna, P. Larenas-Linnemann, D. Morais-Almeida, M. Mullol, J. Murray, R. Naclerio, R. O'Hehir, R.E. Papadopoulos, N.G. Pawankar, R. Potter, P. Ryan, D. Samolinski, B. Schunemann, H.J. Sheikh, A. Simons, F.E.R. Stellato, C. Todo-Bom, A. Tomazic, P.V. Valiulis, A. Valovirta, E. Ventura, M.T. Wickman, M. Young, I. Yorgancioglu, A. Zuberbier, T. Aberer, W. Akdis, C.A. Akdis, M. Annesi-Maesano, I. Ankri, J. Ansotegui, I.J. Anto, J.M. Arnavielhe, S. Asarnoj, A. Arshad, H. Avolio, F. Baiardini, I. Barbara, C. Barbagallo, M. Bateman, E.D. Beghé, B. Bel, E.H. Bennoor, K.S. Benson, M. Białoszewski, A.Z. Bieber, T. Bjermer, L. Blain, H. Blasi, F. Boner, A.L. Bonini, M. Bonini, S. Bosse, I. Bouchard, J. Boulet, L.P. Bourret, R. Bousquet, P.J. Braido, F. Briggs, A.H. Brightling, C.E. Brozek, J. Buhl, R. Bunu, C. Burte, E. Bush, A. Caballero-Fonseca, F. Calderon, M.A. Camuzat, T. Cardona, V. Carreiro-Martins, P. Carriazo, A.M. Carlsen, K.H. Carr, W. Cepeda Sarabia, A.M. Cesari, M. Chatzi, L. Chiron, R. Chivato, T. Chkhartishvili, E. Chuchalin, A.G. Chung, K.F. Ciprandi, G. De Sousa, J.C. Cox, L. Crooks, G. Custovic, A. Dahlen, S.E. Darsow, U. Dedeu, T. Deleanu, D. Denburg, J.A. De Vries, G. Didier, A. Dinh-Xuan, A.T. Dokic, D. Douagui, H. Dray, G. Dubakiene, R. Durham, S.R. Du Toit, G. Dykewicz, M.S. Eklund, P. El-Gamal, Y. Ellers, E. Emuzyte, R. Farrell, J. Fink Wagner, A. Fiocchi, A. Fletcher, M. Forastiere, F. Gaga, M. Gamkrelidze, A. Gemicioǧlu, B. Gereda, J.E. Van Wick, R.G. González Diaz, S. Grisle, I. Grouse, L. Gutter, Z. Guzmán, M.A. Hellquist-Dahl, B. Heinrich, J. Horak, F. Hourihane, J.O.B. Humbert, M. Hyland, M. Iaccarino, G. Jares, E.J. Jeandel, C. Johnston, S.L. Joos, G. Jonquet, O. Jung, K.S. Jutel, M. Kaidashev, I.P. Khaitov, M. Kalayci, O. Kalyoncu, A.F. Kardas, P. Keith, P.K. Kerkhof, M. Kerstjens, H.A.M. Khaltaev, N. Kogevinas, M. Kolek, V. Koppelman, G.H. Kowalski, M.L. Kuitunen, M. Kull, I. Kvedariene, V. Lambrecht, B. Lau, S. Laune, D. Le, L.T.T. Lieberman, P. Lipworth, B. Li, J. Lodrup Carlsen, K.C. Louis, R. Lupinek, C. MacNee, W. Magar, Y. Magnan, A. Mahboub, B. Maier, D. Majer, I. Malva, J. Manning, P. De Manuel Keenoy, E. Marshall, G.D. Masjedi, M.R. Mathieu-Dupas, E. Maurer, M. Mavale-Manuel, S. Melén, E. Melo-Gomes, E. Meltzer, E.O. Mercier, J. Merk, H. Miculinic, N. Mihaltan, F. Milenkovic, B. Millot-Keurinck, J. Mohammad, Y. Momas, I. Mösges, R. Muraro, A. Namazova-Baranova, L. Nadif, R. Neffen, H. Nekam, K. Nieto, A. Niggemann, B. Nogueira-Silva, L. Nogues, M. Nyembue, T.D. Ohta, K. Okamoto, Y. Okubo, K. Olive-Elias, M. Ouedraogo, S. Paggiaro, P. Pali-Schöll, I. Palkonen, S. Panzner, P. Papi, A. Park, H.S. Passalacqua, G. Pedersen, S. Pereira, A.M. Pfaar, O. Picard, R. Pigearias, B. Pin, I. Plavec, D. Pohl, W. Popov, T.A. Portejoie, F. Postma, D. Poulsen, L.K. Price, D. Rabe, K.F. Raciborski, F. Roberts, G. Robalo-Cordeiro, C. Rodenas, F. Rodriguez-Mañas, L. Rolland, C. Roman Rodriguez, M. Romano, A. Rosado-Pinto, J. Rosario, N. Rottem, M. Sanchez-Borges, M. Sastre-Dominguez, J. Scadding, G.K. Scichilone, N. Schmid-Grendelmeier, P. Serrano, E. Shields, M. Siroux, V. Sisul, J.C. Skrindo, I. Smit, H.A. Solé, D. Sooronbaev, T. Spranger, O. Stelmach, R. Sterk, P.J. Strandberg, T. Sunyer, J. Thijs, C. Triggiani, M. Valenta, R. Valero, A. Van Eerd, M. Van Ganse, E. Van Hague, M. Vandenplas, O. Varona, L.L. Vellas, B. Vezzani, G. Vazankari, T. Viegi, G. Vontetsianos, T. Wagenmann, M. Walker, S. Wang, D.Y. Wahn, U. Werfel, T. Whalley, B. Williams, D.M. Williams, S. Wilson, N. Wright, J. Yawn, B.P. Yiallouros, P.K. Yusuf, O.M. Zaidi, A. Zar, H.J. Zernotti, M.E. Zhang, L. Zhong, N. Zidarn, M.

Abstract

The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote the concept of multi-morbidity in asthma and rhinitis and (3) to develop guidelines with all stakeholders that could be used globally for all countries and populations. ARIA - disseminated and implemented in over 70 countries globally - is now focusing on the implementation of emerging technologies for individualized and predictive medicine. MASK [MACVIA (Contre les Maladies Chroniques pour un Vieillissement Actif)-ARIA Sentinel NetworK] uses mobile technology to develop care pathways for the management of rhinitis and asthma by a multi-disciplinary group and by patients themselves. An app (Android and iOS) is available in 20 countries and 15 languages. It uses a visual analogue scale to assess symptom control and work productivity as well as a clinical decision support system. It is associated with an inter-operable tablet for physicians and other health care professionals. The scaling up strategy uses the recommendations of the European Innovation Partnership on Active and Healthy Ageing. The aim of the novel ARIA approach is to provide an active and healthy life to rhinitis sufferers, whatever their age, sex or socio-economic status, in order to reduce health and social inequalities incurred by the disease. © 2016 The Author(s).

Published
2016

31. Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)(Clin Transl Allergy (2016) 6 (29) DOI: 10.1186/s13601-016-0116-9)

Author

Bousquet, J. Farrell, J. Crooks, G. Hellings, P. Bel, E.H. Bewick, M. Chavannes, N.H. De Sousa, J.C. Cruz, A.A. Haahtela, T. Joos, G. Khaltaev, N. Malva, J. Muraro, A. Nogues, M. Palkonen, S. Pedersen, S. Robalo-Cordeiro, C. Samolinski, B. Strandberg, T. Valiulis, A. Yorgancioglu, A. Zuberbier, T. Bedbrook, A. Aberer, W. Adachi, M. Agusti, A. Akdis, C.A. Akdis, M. Ankri, J. Alonso, A. Annesi-Maesano, I. Ansotegui, I.J. Anto, J.M. Arnavielhe, S. Arshad, H. Bai, C. Baiardini, I. Bachert, C. Baigenzhin, A.K. Barbara, C. Bateman, E.D. Beghé, B. Kheder, A.B. Bennoor, K.S. Benson, M. Bergmann, K.C. Bieber, T. Bindslev-Jensen, C. Bjermer, L. Blain, H. Blasi, F. Boner, A.L. Bonini, M. Bonini, S. Bosnic-Anticevitch, S. Boulet, L.P. Bourret, R. Bousquet, P.J. Braido, F. Briggs, A.H. Brightling, C.E. Brozek, J. Buhl, R. Burney, P.G. Bush, A. Caballero-Fonseca, F. Caimmi, D. Calderon, M.A. Calverley, P.M. Camargos, P.A.M. Canonica, G.W. Camuzat, T. Carlsen, K.H. Carr, W. Carriazo, A. Casale, T. Cepeda Sarabia, A.M. Chatzi, L. Chen, Y.Z. Chiron, R. Chkhartishvili, E. Chuchalin, A.G. Chung, K.F. Ciprandi, G. Cirule, I. Cox, L. Costa, D.J. Custovic, A. Dahl, R. Dahlen, S.E. Darsow, U. De Carlo, G. De Blay, F. Dedeu, T. Deleanu, D. De Manuel Keenoy, E. Demoly, P. Denburg, J.A. Devillier, P. Didier, A. Dinh-Xuan, A.T. Djukanovic, R. Dokic, D. Douagui, H. Dray, G. Dubakiene, R. Durham, S.R. Dykewicz, M.S. El-Gamal, Y. Emuzyte, R. Fabbri, L.M. Fletcher, M. Fiocchi, A. Fink Wagner, A. Fonseca, J. Fokkens, W.J. Forastiere, F. Frith, P. Gaga, M. Gamkrelidze, A. Garces, J. Garcia-Aymerich, J. Gemicioǧlu, B. Gereda, J.E. González Diaz, S. Gotua, M. Grisle, I. Grouse, L. Gutter, Z. Guzmán, M.A. Heaney, L.G. Hellquist-Dahl, B. Henderson, D. Hendry, A. Heinrich, J. Heve, D. Horak, F. Hourihane, J.O.B. Howarth, P. Humbert, M. Hyland, M.E. Illario, M. Ivancevich, J.C. Jardim, J.R. Jares, E.J. Jeandel, C. Jenkins, C. Johnston, S.L. Jonquet, O. Julge, K. Jung, K.S. Just, J. Kaidashev, I.P. Khaito and Bousquet, J. Farrell, J. Crooks, G. Hellings, P. Bel, E.H. Bewick, M. Chavannes, N.H. De Sousa, J.C. Cruz, A.A. Haahtela, T. Joos, G. Khaltaev, N. Malva, J. Muraro, A. Nogues, M. Palkonen, S. Pedersen, S. Robalo-Cordeiro, C. Samolinski, B. Strandberg, T. Valiulis, A. Yorgancioglu, A. Zuberbier, T. Bedbrook, A. Aberer, W. Adachi, M. Agusti, A. Akdis, C.A. Akdis, M. Ankri, J. Alonso, A. Annesi-Maesano, I. Ansotegui, I.J. Anto, J.M. Arnavielhe, S. Arshad, H. Bai, C. Baiardini, I. Bachert, C. Baigenzhin, A.K. Barbara, C. Bateman, E.D. Beghé, B. Kheder, A.B. Bennoor, K.S. Benson, M. Bergmann, K.C. Bieber, T. Bindslev-Jensen, C. Bjermer, L. Blain, H. Blasi, F. Boner, A.L. Bonini, M. Bonini, S. Bosnic-Anticevitch, S. Boulet, L.P. Bourret, R. Bousquet, P.J. Braido, F. Briggs, A.H. Brightling, C.E. Brozek, J. Buhl, R. Burney, P.G. Bush, A. Caballero-Fonseca, F. Caimmi, D. Calderon, M.A. Calverley, P.M. Camargos, P.A.M. Canonica, G.W. Camuzat, T. Carlsen, K.H. Carr, W. Carriazo, A. Casale, T. Cepeda Sarabia, A.M. Chatzi, L. Chen, Y.Z. Chiron, R. Chkhartishvili, E. Chuchalin, A.G. Chung, K.F. Ciprandi, G. Cirule, I. Cox, L. Costa, D.J. Custovic, A. Dahl, R. Dahlen, S.E. Darsow, U. De Carlo, G. De Blay, F. Dedeu, T. Deleanu, D. De Manuel Keenoy, E. Demoly, P. Denburg, J.A. Devillier, P. Didier, A. Dinh-Xuan, A.T. Djukanovic, R. Dokic, D. Douagui, H. Dray, G. Dubakiene, R. Durham, S.R. Dykewicz, M.S. El-Gamal, Y. Emuzyte, R. Fabbri, L.M. Fletcher, M. Fiocchi, A. Fink Wagner, A. Fonseca, J. Fokkens, W.J. Forastiere, F. Frith, P. Gaga, M. Gamkrelidze, A. Garces, J. Garcia-Aymerich, J. Gemicioǧlu, B. Gereda, J.E. González Diaz, S. Gotua, M. Grisle, I. Grouse, L. Gutter, Z. Guzmán, M.A. Heaney, L.G. Hellquist-Dahl, B. Henderson, D. Hendry, A. Heinrich, J. Heve, D. Horak, F. Hourihane, J.O.B. Howarth, P. Humbert, M. Hyland, M.E. Illario, M. Ivancevich, J.C. Jardim, J.R. Jares, E.J. Jeandel, C. Jenkins, C. Johnston, S.L. Jonquet, O. Julge, K. Jung, K.S. Just, J. Kaidashev, I.P. Khaito

Published
2017

32. Building bridges for innovation in ageing:synergies between action groups of the EIP on AHA

Author

Bousquet, Jean, Bewick, M., Cano, A., Eklund, P., Fico, G., Goswami, N., Guldemond, N. A., Henderson, D., Hinkema, M.J., Liotta, G., Mair, A., Molloy, W., Monaco, A., Monsonis-Paya, I., Nizinska, A., Papadopoulos, H., Pavlickova, A., Pecorelli, S., Prados-Torres, A., Roller-Wirnsberger, R.E., Somekh, D., Vera-Muñoz, C., Visser, F., Farrell, J., Malva, J., Andersen Ranberg, K., Camuzat, T., Carriazo, A.M., Crooks, G., Gutter, Z., Iaccarino, G., de Keenoy, E. Manuel, Moda, G., Rodriguez-Mañas, L., Vontetsianos, T., Abreu, C., Alonso, J., Alonso-Bouzon, C., Ankri, J., Arredondo, M.T., Avolio, F., Bedbrook, A., Białoszewski, A.Z., Blain, H., Bourret, R., Cabrera-Umpierrez, M.F., Catala, A., O’Caoimh, R., Cesari, M., Chavannes, N.H., Correia-da-Sousa, J., Dedeu, T., Ferrando, M., Ferri, M., Fokkens, W.J., Garcia-Lizana, F., Guérin, O., Hellings, P.W., Haahtela, T., Illario, M., Inzerilli, M.C., Lodrup Carlsen, K.C., Kardas, P., Keil, T., Maggio, M., Mendez-Zorrilla, A., Menditto, E., Mercier, J., Michel, J.P., Murray, R., Nogues, M., O’Byrne-Maguire, I., Pappa, D., Parent, A.S., Pastorino, M., Robalo-Cordeiro, C., Samolinski, B., Siciliano, P., Teixeira, A.M., Tsartara, S.I., Valiulis, A., Vandenplas, O., Vasankari, T., Vellas, B., Vollenbroek-Hutten, M., Wickman, M., Yorgancioglu, A., Zuberbier, T., Barbagallo, M., Canonica, G.W., Klimek, L., Maggi, S., Aberer, W., Akdis, C., Adcock, I.M., Agache, I., Albera, C., Alonso-Trujillo, F., Angel Guarcia, M., Annesi-Maesano, I., Apostolo, J., Arshad, S.H., Attalin, V., Avignon, A., Bachert, C., Baroni, I., Bel, E., Benson, M., Bescos, C., Blasi, F., Barbara, C., Bergmann, K.C., Bernard, P. L., Bonini, S., Bousquet, P.J., Branchini, B., Brightling, C.E., Bruguière, V., Bunu, C., Bush, A., Caimmi, D.P., Calderon, M. A., Canovas, G., Cardona, V., Carlsen, K.H., Cesario, A., Chkhartishvili, E., Chiron, R., Chivato, T., Chung, K.F., D’Angelantonio, M., de Carlo, G., Cholley, D., Chorin, F., Combe, B., Compas, B., Costa, D.J., Costa, E., Coste, O., Coupet, A.L., Crepaldi, G., Custovic, A., Dahl, R., Dahlen, S.E., Demoly, P., Devillier, P., Didier, A., Dinh-Xuan, A.T., Djukanovic, R., Dokic, D., du Toit, G., Dubakiene, R., Dupeyron, A., Emuzyte, R., Fiocchi, A., Wagner, A., Fletcher, M., Fonseca, J., Fougère, B., Gamkrelidze, A., Garces, G., Garcia-Aymeric, J., Garcia-Zapirain, B., Gemicioğlu, B., Gouder, C., Hellquist-Dahl, B., Hermosilla-Gimeno, I., Héve, D., Holland, C., Humbert, M., Hyland, M., Johnston, S.L., Just, J., Jutel, M., Kaidashev, I.P., Khaitov, M., Kalayci, O., Kalyoncu, A.F., Keijser, W., Kerstjens, H., Knezović, J., Kowalski, M., Koppelman, G.H., Kotska, T., Kovac, M., Kull, I., Kuna, P., Kvedariene, V., Lepore, V., Macnee, W., Magnan, A., Majer, I., Manning, P., Marcucci, M., Marti, T., Masoli, M., Melen, E., Miculinic, N., Mihaltan, F., Milenkovic, B., Millot-Keurinck, J., Mlinarić, H., Momas, I., Montefort, S., Morais-Almeida, M., Moreno-Casbas, T., Mösges, R., Mullol, J., Nadif, R., Nalin, M., Navarro-Pardo, E., Nekam, K., Ninot, G., Paccard, D., Pais, S., Palummeri, E., Panzner, P., Papadopoulos, N.K., Papanikolaou, C., Passalacqua, G., Pastor, E., Perrot, M., Plavec, D., Popov, T.A., Postma, D. S., Price, D., Raffort, N., Reuzeau, J.C., Robine, J.M., Rodenas, F., Robusto, F., Roche, N., Romano, A., Romano, V., Rosado-Pinto, J., Roubille, F., Ruiz, F., Ryan, D., Salcedo, T., Schmid-Grendelmeier, P., Schulz, H., Schunemann, H.J., Serrano, E., Sheikh, A., Shields, M., Siafakas, N., Scichilone, N., Skrindo, I., Smit, H. A., Sourdet, S., Sousa-Costa, E., Spranger, O., Sooronbaev, T., Sruk, V., Sterk, P. J., Todo-Bom, A., Touchon, J., Tramontano, D., Triggiani, M., Tsartara, S. I., Valero, A. L., Valovirta, E., van Ganse, E., van Hage, M., van Den Berge, M., Ventura, M. T., Vergara, I., Vezzani, G., Vidal, D., Viegi, G., Wagemann, M., Whalley, B., Wilson, N., Yiallouros, P. K., Žagar, M., Zaidi, A., Zidarn, M., Hoogerwerf, E. J., Usero, J., Zuffada, R., Senn, A., de Oliveira-Alves, B., Bousquet, Jean, Bewick, M., Cano, A., Eklund, P., Fico, G., Goswami, N., Guldemond, N. A., Henderson, D., Hinkema, M.J., Liotta, G., Mair, A., Molloy, W., Monaco, A., Monsonis-Paya, I., Nizinska, A., Papadopoulos, H., Pavlickova, A., Pecorelli, S., Prados-Torres, A., Roller-Wirnsberger, R.E., Somekh, D., Vera-Muñoz, C., Visser, F., Farrell, J., Malva, J., Andersen Ranberg, K., Camuzat, T., Carriazo, A.M., Crooks, G., Gutter, Z., Iaccarino, G., de Keenoy, E. Manuel, Moda, G., Rodriguez-Mañas, L., Vontetsianos, T., Abreu, C., Alonso, J., Alonso-Bouzon, C., Ankri, J., Arredondo, M.T., Avolio, F., Bedbrook, A., Białoszewski, A.Z., Blain, H., Bourret, R., Cabrera-Umpierrez, M.F., Catala, A., O’Caoimh, R., Cesari, M., Chavannes, N.H., Correia-da-Sousa, J., Dedeu, T., Ferrando, M., Ferri, M., Fokkens, W.J., Garcia-Lizana, F., Guérin, O., Hellings, P.W., Haahtela, T., Illario, M., Inzerilli, M.C., Lodrup Carlsen, K.C., Kardas, P., Keil, T., Maggio, M., Mendez-Zorrilla, A., Menditto, E., Mercier, J., Michel, J.P., Murray, R., Nogues, M., O’Byrne-Maguire, I., Pappa, D., Parent, A.S., Pastorino, M., Robalo-Cordeiro, C., Samolinski, B., Siciliano, P., Teixeira, A.M., Tsartara, S.I., Valiulis, A., Vandenplas, O., Vasankari, T., Vellas, B., Vollenbroek-Hutten, M., Wickman, M., Yorgancioglu, A., Zuberbier, T., Barbagallo, M., Canonica, G.W., Klimek, L., Maggi, S., Aberer, W., Akdis, C., Adcock, I.M., Agache, I., Albera, C., Alonso-Trujillo, F., Angel Guarcia, M., Annesi-Maesano, I., Apostolo, J., Arshad, S.H., Attalin, V., Avignon, A., Bachert, C., Baroni, I., Bel, E., Benson, M., Bescos, C., Blasi, F., Barbara, C., Bergmann, K.C., Bernard, P. L., Bonini, S., Bousquet, P.J., Branchini, B., Brightling, C.E., Bruguière, V., Bunu, C., Bush, A., Caimmi, D.P., Calderon, M. A., Canovas, G., Cardona, V., Carlsen, K.H., Cesario, A., Chkhartishvili, E., Chiron, R., Chivato, T., Chung, K.F., D’Angelantonio, M., de Carlo, G., Cholley, D., Chorin, F., Combe, B., Compas, B., Costa, D.J., Costa, E., Coste, O., Coupet, A.L., Crepaldi, G., Custovic, A., Dahl, R., Dahlen, S.E., Demoly, P., Devillier, P., Didier, A., Dinh-Xuan, A.T., Djukanovic, R., Dokic, D., du Toit, G., Dubakiene, R., Dupeyron, A., Emuzyte, R., Fiocchi, A., Wagner, A., Fletcher, M., Fonseca, J., Fougère, B., Gamkrelidze, A., Garces, G., Garcia-Aymeric, J., Garcia-Zapirain, B., Gemicioğlu, B., Gouder, C., Hellquist-Dahl, B., Hermosilla-Gimeno, I., Héve, D., Holland, C., Humbert, M., Hyland, M., Johnston, S.L., Just, J., Jutel, M., Kaidashev, I.P., Khaitov, M., Kalayci, O., Kalyoncu, A.F., Keijser, W., Kerstjens, H., Knezović, J., Kowalski, M., Koppelman, G.H., Kotska, T., Kovac, M., Kull, I., Kuna, P., Kvedariene, V., Lepore, V., Macnee, W., Magnan, A., Majer, I., Manning, P., Marcucci, M., Marti, T., Masoli, M., Melen, E., Miculinic, N., Mihaltan, F., Milenkovic, B., Millot-Keurinck, J., Mlinarić, H., Momas, I., Montefort, S., Morais-Almeida, M., Moreno-Casbas, T., Mösges, R., Mullol, J., Nadif, R., Nalin, M., Navarro-Pardo, E., Nekam, K., Ninot, G., Paccard, D., Pais, S., Palummeri, E., Panzner, P., Papadopoulos, N.K., Papanikolaou, C., Passalacqua, G., Pastor, E., Perrot, M., Plavec, D., Popov, T.A., Postma, D. S., Price, D., Raffort, N., Reuzeau, J.C., Robine, J.M., Rodenas, F., Robusto, F., Roche, N., Romano, A., Romano, V., Rosado-Pinto, J., Roubille, F., Ruiz, F., Ryan, D., Salcedo, T., Schmid-Grendelmeier, P., Schulz, H., Schunemann, H.J., Serrano, E., Sheikh, A., Shields, M., Siafakas, N., Scichilone, N., Skrindo, I., Smit, H. A., Sourdet, S., Sousa-Costa, E., Spranger, O., Sooronbaev, T., Sruk, V., Sterk, P. J., Todo-Bom, A., Touchon, J., Tramontano, D., Triggiani, M., Tsartara, S. I., Valero, A. L., Valovirta, E., van Ganse, E., van Hage, M., van Den Berge, M., Ventura, M. T., Vergara, I., Vezzani, G., Vidal, D., Viegi, G., Wagemann, M., Whalley, B., Wilson, N., Yiallouros, P. K., Žagar, M., Zaidi, A., Zidarn, M., Hoogerwerf, E. J., Usero, J., Zuffada, R., Senn, A., and de Oliveira-Alves, B.

Abstract

The Strategic Implementation Plan of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) proposed six Action Groups. After almost three years of activity, many achievements have been obtained through commitments or collaborative work of the Action Groups. However, they have often worked in silos and, consequently, synergies between Action Groups have been proposed to strengthen the triple win of the EIP on AHA. The paper presents the methodology and current status of the Task Force on EIP on AHA synergies. Synergies are in line with the Action Groups’ new Renovated Action Plan (2016-2018) to ensure that their future objectives are coherent and fully connected. The outcomes and impact of synergies are using the Monitoring and Assessment Framework for the EIP on AHA (MAFEIP). Eight proposals for synergies have been approved by the Task Force: Five cross-cutting synergies which can be used for all current and future synergies as they consider overarching domains (appropriate polypharmacy, citizen empowerment, teaching and coaching on AHA, deployment of synergies to EU regions, Responsible Research and Innovation), and three cross-cutting synergies focussing on current Action Group activities (falls, frailty, integrated care and chronic respiratory diseases).

Published
2017

33. MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): The new generation guideline implementation

Author

Bousquet, J. Schunemann, H.J. Fonseca, J. Samolinski, B. Bachert, C. Canonica, G.W. Casale, T. Cruz, A.A. Demoly, P. Hellings, P. Valiulis, A. Wickman, M. Zuberbier, T. Bosnic-Anticevitch, S. Bedbrook, A. Bergmann, K.C. Caimmi, D. Dahl, R. Fokkens, W.J. Grisle, I. Lodrup Carlsen, K. Mullol, J. Muraro, A. Palkonen, S. Papadopoulos, N. Passalacqua, G. Ryan, D. Valovirta, E. Yorgancioglu, A. Aberer, W. Agache, I. Adachi, M. Akdis, C.A. Akdis, M. Annesi-Maesano, I. Ansotegui, I.J. Anto, J.M. Arnavielhe, S. Arshad, H. Baiardini, I. Baigenzhin, A.K. Barbara, C. Bateman, E.D. Beghé, B. Bel, E.H. Ben Kheder, A. Bennoor, K.S. Benson, M. Bewick, M. Bieber, T. Bindslev-Jensen, C. Bjermer, L. Blain, H. Boner, A.L. Boulet, L.P. Bonini, M. Bonini, S. Bosse, I. Bourret, R. Bousquet, P.J. Braido, F. Briggs, A.H. Brightling, C.E. Brozek, J. Buhl, R. Burney, P.G. Bush, A. Caballero-Fonseca, F. Calderon, M.A. Camargos, P.A.M. Camuzat, T. Carlsen, K.H. Carr, W. Cepeda Sarabia, A.M. Chavannes, N.H. Chatzi, L. Chen, Y.Z. Chiron, R. Chkhartishvili, E. Chuchalin, A.G. Ciprandi, G. Cirule, I. Correia De Sousa, J. Cox, L. Crooks, G. Costa, D.J. Custovic, A. Dahlen, S.E. Darsow, U. De Carlo, G. De Blay, F. Dedeu, T. Deleanu, D. Denburg, J.A. Devillier, P. Didier, A. Dinh-Xuan, A.T. Dokic, D. Douagui, H. Dray, G. Dubakiene, R. Durham, S.R. Dykewicz, M.S. El-Gamal, Y. Emuzyte, R. Fink Wagner, A. Fletcher, M. Fiocchi, A. Forastiere, F. Gamkrelidze, A. Gemicioʇlu, B. Gereda, J.E. González Diaz, S. Gotua, M. Grouse, L. Guzmán, M.A. Haahtela, T. Hellquist-Dahl, B. Heinrich, J. Horak, F. Hourihane, J.O.B. Howarth, P. Humbert, M. Hyland, M.E. Ivancevich, J.C. Jares, E.J. Johnston, S.L. Joos, G. Jonquet, O. Jung, K.S. Just, J. Kaidashev, I.P. Kalayci, O. Kalyoncu, A.F. Keil, T. Keith, P.K. Khaltaev, N. Klimek, L. Koffi N'Goran, B. Kolek, V. Koppelman, G.H. Kowalski, M.L. Kull, I. Kuna, P. Kvedariene, V. Lambrecht, B. Lau, S. Larenas-Linnemann, D. Laune, D. Le, L.T.T. Lieberman, P. Lipworth, B. Li, J. Louis, R. Magard, Y. Magnan, A. Mahboub, B. Majer, I. Makela, M.J. Manning, P. De Manuel Keenoy, E. Marshall, G.D. Masjedi, M.R. Maurer, M. Mavale-Manuel, S. Melén, E. Melo-Gomes, E. Meltzer, E.O. Merk, H. Miculinic, N. Mihaltan, F. Milenkovic, B. Mohammad, Y. Molimard, M. Momas, I. Montilla-Santana, A. Morais-Almeida, M. Mösges, R. Namazova-Baranova, L. Naclerio, R. Neou, A. Neffen, H. Nekam, K. Niggemann, B. Nyembue, T.D. O'Hehir, R.E. Ohta, K. Okamoto, Y. Okubo, K. Ouedraogo, S. Paggiaro, P. Pali-Schöll, I. Palmer, S. Panzner, P. Papi, A. Park, H.S. Pavord, I. Pawankar, R. Pfaar, O. Picard, R. Pigearias, B. Pin, I. Plavec, D. Pohl, W. Popov, T.A. Portejoie, F. Postma, D. Potter, P. Price, D. Rabe, K.F. Raciborski, F. Radier Pontal, F. Repka-Ramirez, S. Robalo-Cordeiro, C. Rolland, C. Rosado-Pinto, J. Reitamo, S. Rodenas, F. Roman Rodriguez, M. Romano, A. Rosario, N. Rosenwasser, L. Rottem, M. Sanchez-Borges, M. Scadding, G.K. Serrano, E. Schmid-Grendelmeier, P. Sheikh, A. Simons, F.E.R. Sisul, J.C. Skrindo, I. Smit, H.A. Solé, D. Sooronbaev, T. Spranger, O. Stelmach, R. Strandberg, T. Sunyer, J. Thijs, C. Todo-Bom, A. Triggiani, M. Valenta, R. Valero, A.L. Van Hage, M. Vandenplas, O. Vezzani, G. Vichyanond, P. Viegi, G. Wagenmann, M. Walker, S. Wang, D.Y. Wahn, U. Williams, D.M. Wright, J. Yawn, B.P. Yiallouros, P.K. Yusuf, O.M. Zar, H.J. Zernotti, M.E. Zhang, L. Zhong, N. Zidarn, M. Mercier, J.

Abstract

Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for integrated care pathways, innovation in clinical trials and, above all, patient empowerment. MASK-rhinitis (MACVIA-ARIA Sentinel NetworK for allergic rhinitis) is a simple system centred around the patient which was devised to fill many of these gaps using Information and Communications Technology (ICT) tools and a clinical decision support system (CDSS) based on the most widely used guideline in allergic rhinitis and its asthma comorbidity (ARIA 2015 revision). It is one of the implementation systems of Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA). Three tools are used for the electronic monitoring of allergic diseases: a cell phone-based daily visual analogue scale (VAS) assessment of disease control, CARAT (Control of Allergic Rhinitis and Asthma Test) and e-Allergy screening (premedical system of early diagnosis of allergy and asthma based on online tools). These tools are combined with a clinical decision support system (CDSS) and are available in many languages. An e-CRF and an e-learning tool complete MASK. MASK is flexible and other tools can be added. It appears to be an advanced, global and integrated ICT answer for many unmet needs in allergic diseases which will improve policies and standards. © 2015 John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

Published
2015

34. MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis

Author

Bousquet, J. Schünemann, H.J. Hellings, P.W. Arnavielhe, S. Bachert, C. Bedbrook, A. Bergmann, K.-C. Bosnic-Anticevich, S. Brozek, J. Calderon, M. Canonica, G.W. Casale, T.B. Chavannes, N.H. Cox, L. Chrystyn, H. Cruz, A.A. Dahl, R. De Carlo, G. Demoly, P. Devillier, P. Dray, G. Fletcher, M. Fokkens, W.J. Fonseca, J. Gonzalez-Diaz, S.N. Grouse, L. Keil, T. Kuna, P. Larenas-Linnemann, D. Lodrup Carlsen, K.C. Meltzer, E.O. Mullol, J. Muraro, A. Naclerio, R.N. Palkonen, S. Papadopoulos, N.G. Passalacqua, G. Price, D. Ryan, D. Samolinski, B. Scadding, G.K. Sheikh, A. Spertini, F. Valiulis, A. Valovirta, E. Walker, S. Wickman, M. Yorgancioglu, A. Haahtela, T. Zuberbier, T. Aberer, W. Adachi, M. Agache, I. Akdis, C. Akdis, M. Annesi-Maesano, I. Ansotegui, I.J. Anto, J.M. Arshad, S.H. Baiardini, I. Baigenzhin, A.K. Barbara, C. Bateman, E.D. Beghé, B. Bel, E.H. Ben Kheder, A. Bennoor, K.S. Benson, M. Bernstein, D. Michael, B. Thomas, B. Bindslev-Jensen, C. Bjermer, L. Blain, H. Boner, A. Bonini, M. Bonini, S. Bosse, I. Bouchard, J. Boulet, L.-P. Bourret, R.A. Bousquet, P.J. Braido, F. Briggs, A.H. Brightling, C.E. Buhl, R. Burney, P. Bush, A. Caballero-Fonseca, F. Caimmi, D.P. Camargos, P. Camuzat, T. Carlsen, K.-H. Carr, W. Casale, T.B. Sarabia, A.C. Chatzi, L. Chen, Y. Chiron, R. Chkhartishvili, E. Chuchalin, A. Ciprandi, G. Cirule, I. Correia de Sousa, J. Costa, D. Crooks, G. Custovic, A. Dahlen, S.-E. Darsow, U. De Blay, F. De Manuel Keenoy, E. Dedeu, T. Deleanu, D. Denburg, J. Didier, A. Dinh-Xuan, A.-T. Dokic, D. Douagui, H.B. Dubakiene, R. Durham, S. Dykewicz, M. El-Gamal, Y. Emuzyte, R. Fink-Wagner, A. Fiocchi, A. Forastiere, F. Gamkrelidze, A. Gemicioğlu, B. Gereda, J.E. Gerth van Wijk, R. Gotua, M. Grisle, I. Guzmán, M.A. Haahtela, T. Heinrich, J. Hellquist-Dahl, B. Horak, F. Howarth, P.H. Humbert, M. Hyland, M. Ivancevich, J.-C. Jares, E.J. Johnston, S.L. Jonquet, O. Joos, G. Jung, K.-S. Just, J. Jutel, M. Kaidashev, I.P. Khaitov, M. Kalayci, O. Kalyoncu, F. Keith and Bousquet, J. Schünemann, H.J. Hellings, P.W. Arnavielhe, S. Bachert, C. Bedbrook, A. Bergmann, K.-C. Bosnic-Anticevich, S. Brozek, J. Calderon, M. Canonica, G.W. Casale, T.B. Chavannes, N.H. Cox, L. Chrystyn, H. Cruz, A.A. Dahl, R. De Carlo, G. Demoly, P. Devillier, P. Dray, G. Fletcher, M. Fokkens, W.J. Fonseca, J. Gonzalez-Diaz, S.N. Grouse, L. Keil, T. Kuna, P. Larenas-Linnemann, D. Lodrup Carlsen, K.C. Meltzer, E.O. Mullol, J. Muraro, A. Naclerio, R.N. Palkonen, S. Papadopoulos, N.G. Passalacqua, G. Price, D. Ryan, D. Samolinski, B. Scadding, G.K. Sheikh, A. Spertini, F. Valiulis, A. Valovirta, E. Walker, S. Wickman, M. Yorgancioglu, A. Haahtela, T. Zuberbier, T. Aberer, W. Adachi, M. Agache, I. Akdis, C. Akdis, M. Annesi-Maesano, I. Ansotegui, I.J. Anto, J.M. Arshad, S.H. Baiardini, I. Baigenzhin, A.K. Barbara, C. Bateman, E.D. Beghé, B. Bel, E.H. Ben Kheder, A. Bennoor, K.S. Benson, M. Bernstein, D. Michael, B. Thomas, B. Bindslev-Jensen, C. Bjermer, L. Blain, H. Boner, A. Bonini, M. Bonini, S. Bosse, I. Bouchard, J. Boulet, L.-P. Bourret, R.A. Bousquet, P.J. Braido, F. Briggs, A.H. Brightling, C.E. Buhl, R. Burney, P. Bush, A. Caballero-Fonseca, F. Caimmi, D.P. Camargos, P. Camuzat, T. Carlsen, K.-H. Carr, W. Casale, T.B. Sarabia, A.C. Chatzi, L. Chen, Y. Chiron, R. Chkhartishvili, E. Chuchalin, A. Ciprandi, G. Cirule, I. Correia de Sousa, J. Costa, D. Crooks, G. Custovic, A. Dahlen, S.-E. Darsow, U. De Blay, F. De Manuel Keenoy, E. Dedeu, T. Deleanu, D. Denburg, J. Didier, A. Dinh-Xuan, A.-T. Dokic, D. Douagui, H.B. Dubakiene, R. Durham, S. Dykewicz, M. El-Gamal, Y. Emuzyte, R. Fink-Wagner, A. Fiocchi, A. Forastiere, F. Gamkrelidze, A. Gemicioğlu, B. Gereda, J.E. Gerth van Wijk, R. Gotua, M. Grisle, I. Guzmán, M.A. Haahtela, T. Heinrich, J. Hellquist-Dahl, B. Horak, F. Howarth, P.H. Humbert, M. Hyland, M. Ivancevich, J.-C. Jares, E.J. Johnston, S.L. Jonquet, O. Joos, G. Jung, K.-S. Just, J. Jutel, M. Kaidashev, I.P. Khaitov, M. Kalayci, O. Kalyoncu, F. Keith

Abstract

The selection of pharmacotherapy for patients with allergic rhinitis (AR) depends on several factors, including age, prominent symptoms, symptom severity, control of AR, patient preferences, and cost. Allergen exposure and the resulting symptoms vary, and treatment adjustment is required. Clinical decision support systems (CDSSs) might be beneficial for the assessment of disease control. CDSSs should be based on the best evidence and algorithms to aid patients and health care professionals to jointly determine treatment and its step-up or step-down strategy depending on AR control. Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR [fighting chronic diseases for active and healthy ageing]), one of the reference sites of the European Innovation Partnership on Active and Healthy Ageing, has initiated an allergy sentinel network (the MACVIA-ARIA Sentinel Network). A CDSS is currently being developed to optimize AR control. An algorithm developed by consensus is presented in this article. This algorithm should be confirmed by appropriate trials. © 2016 The Authors

Published
2016

35. Building bridges for innovation in ageing:synergies between action groups of the EIP on AHA

Author

Bousquet, Jean, Bewick, M., Cano, A., Eklund, P., Fico, G., Goswami, N., Guldemond, N. A., Henderson, D., Hinkema, M.J., Liotta, G., Mair, A., Molloy, W., Monaco, A., Monsonis-Paya, I., Nizinska, A., Papadopoulos, H., Pavlickova, A., Pecorelli, S., Prados-Torres, A., Roller-Wirnsberger, R.E., Somekh, D., Vera-Muñoz, C., Visser, F., Farrell, J., Malva, J., Andersen Ranberg, K., Camuzat, T., Carriazo, A.M., Crooks, G., Gutter, Z., Iaccarino, G., de Keenoy, E. Manuel, Moda, G., Rodriguez-Mañas, L., Vontetsianos, T., Abreu, C., Alonso, J., Alonso-Bouzon, C., Ankri, J., Arredondo, M.T., Avolio, F., Bedbrook, A., Białoszewski, A.Z., Blain, H., Bourret, R., Cabrera-Umpierrez, M.F., Catala, A., O’Caoimh, R., Cesari, M., Chavannes, N.H., Correia-da-Sousa, J., Dedeu, T., Ferrando, M., Ferri, M., Fokkens, W.J., Garcia-Lizana, F., Guérin, O., Hellings, P.W., Haahtela, T., Illario, M., Inzerilli, M.C., Lodrup Carlsen, K.C., Kardas, P., Keil, T., Maggio, M., Mendez-Zorrilla, A., Menditto, E., Mercier, J., Michel, J.P., Murray, R., Nogues, M., O’Byrne-Maguire, I., Pappa, D., Parent, A.S., Pastorino, M., Robalo-Cordeiro, C., Samolinski, B., Siciliano, P., Teixeira, A.M., Tsartara, S.I., Valiulis, A., Vandenplas, O., Vasankari, T., Vellas, B., Vollenbroek-Hutten, M., Wickman, M., Yorgancioglu, A., Zuberbier, T., Barbagallo, M., Canonica, G.W., Klimek, L., Maggi, S., Aberer, W., Akdis, C., Adcock, I.M., Agache, I., Albera, C., Alonso-Trujillo, F., Angel Guarcia, M., Annesi-Maesano, I., Apostolo, J., Arshad, S.H., Attalin, V., Avignon, A., Bachert, C., Baroni, I., Bel, E., Benson, M., Bescos, C., Blasi, F., Barbara, C., Bergmann, K.C., Bernard, P. L., Bonini, S., Bousquet, P.J., Branchini, B., Brightling, C.E., Bruguière, V., Bunu, C., Bush, A., Caimmi, D.P., Calderon, M. A., Canovas, G., Cardona, V., Carlsen, K.H., Cesario, A., Chkhartishvili, E., Chiron, R., Chivato, T., Chung, K.F., D’Angelantonio, M., de Carlo, G., Cholley, D., Chorin, F., Combe, B., Compas, B., Costa, D.J., Costa, E., Coste, O., Coupet, A.L., Crepaldi, G., Custovic, A., Dahl, R., Dahlen, S.E., Demoly, P., Devillier, P., Didier, A., Dinh-Xuan, A.T., Djukanovic, R., Dokic, D., du Toit, G., Dubakiene, R., Dupeyron, A., Emuzyte, R., Fiocchi, A., Wagner, A., Fletcher, M., Fonseca, J., Fougère, B., Gamkrelidze, A., Garces, G., Garcia-Aymeric, J., Garcia-Zapirain, B., Gemicioğlu, B., Gouder, C., Hellquist-Dahl, B., Hermosilla-Gimeno, I., Héve, D., Holland, C., Humbert, M., Hyland, M., Johnston, S.L., Just, J., Jutel, M., Kaidashev, I.P., Khaitov, M., Kalayci, O., Kalyoncu, A.F., Keijser, W., Kerstjens, H., Knezović, J., Kowalski, M., Koppelman, G.H., Kotska, T., Kovac, M., Kull, I., Kuna, P., Kvedariene, V., Lepore, V., Macnee, W., Magnan, A., Majer, I., Manning, P., Marcucci, M., Marti, T., Masoli, M., Melen, E., Miculinic, N., Mihaltan, F., Milenkovic, B., Millot-Keurinck, J., Mlinarić, H., Momas, I., Montefort, S., Morais-Almeida, M., Moreno-Casbas, T., Mösges, R., Mullol, J., Nadif, R., Nalin, M., Navarro-Pardo, E., Nekam, K., Ninot, G., Paccard, D., Pais, S., Palummeri, E., Panzner, P., Papadopoulos, N.K., Papanikolaou, C., Passalacqua, G., Pastor, E., Perrot, M., Plavec, D., Popov, T.A., Postma, D. S., Price, D., Raffort, N., Reuzeau, J.C., Robine, J.M., Rodenas, F., Robusto, F., Roche, N., Romano, A., Romano, V., Rosado-Pinto, J., Roubille, F., Ruiz, F., Ryan, D., Salcedo, T., Schmid-Grendelmeier, P., Schulz, H., Schunemann, H.J., Serrano, E., Sheikh, A., Shields, M., Siafakas, N., Scichilone, N., Skrindo, I., Smit, H. A., Sourdet, S., Sousa-Costa, E., Spranger, O., Sooronbaev, T., Sruk, V., Sterk, P. J., Todo-Bom, A., Touchon, J., Tramontano, D., Triggiani, M., Tsartara, S. I., Valero, A. L., Valovirta, E., van Ganse, E., van Hage, M., van Den Berge, M., Ventura, M. T., Vergara, I., Vezzani, G., Vidal, D., Viegi, G., Wagemann, M., Whalley, B., Wilson, N., Yiallouros, P. K., Žagar, M., Zaidi, A., Zidarn, M., Hoogerwerf, E. J., Usero, J., Zuffada, R., Senn, A., de Oliveira-Alves, B., Bousquet, Jean, Bewick, M., Cano, A., Eklund, P., Fico, G., Goswami, N., Guldemond, N. A., Henderson, D., Hinkema, M.J., Liotta, G., Mair, A., Molloy, W., Monaco, A., Monsonis-Paya, I., Nizinska, A., Papadopoulos, H., Pavlickova, A., Pecorelli, S., Prados-Torres, A., Roller-Wirnsberger, R.E., Somekh, D., Vera-Muñoz, C., Visser, F., Farrell, J., Malva, J., Andersen Ranberg, K., Camuzat, T., Carriazo, A.M., Crooks, G., Gutter, Z., Iaccarino, G., de Keenoy, E. Manuel, Moda, G., Rodriguez-Mañas, L., Vontetsianos, T., Abreu, C., Alonso, J., Alonso-Bouzon, C., Ankri, J., Arredondo, M.T., Avolio, F., Bedbrook, A., Białoszewski, A.Z., Blain, H., Bourret, R., Cabrera-Umpierrez, M.F., Catala, A., O’Caoimh, R., Cesari, M., Chavannes, N.H., Correia-da-Sousa, J., Dedeu, T., Ferrando, M., Ferri, M., Fokkens, W.J., Garcia-Lizana, F., Guérin, O., Hellings, P.W., Haahtela, T., Illario, M., Inzerilli, M.C., Lodrup Carlsen, K.C., Kardas, P., Keil, T., Maggio, M., Mendez-Zorrilla, A., Menditto, E., Mercier, J., Michel, J.P., Murray, R., Nogues, M., O’Byrne-Maguire, I., Pappa, D., Parent, A.S., Pastorino, M., Robalo-Cordeiro, C., Samolinski, B., Siciliano, P., Teixeira, A.M., Tsartara, S.I., Valiulis, A., Vandenplas, O., Vasankari, T., Vellas, B., Vollenbroek-Hutten, M., Wickman, M., Yorgancioglu, A., Zuberbier, T., Barbagallo, M., Canonica, G.W., Klimek, L., Maggi, S., Aberer, W., Akdis, C., Adcock, I.M., Agache, I., Albera, C., Alonso-Trujillo, F., Angel Guarcia, M., Annesi-Maesano, I., Apostolo, J., Arshad, S.H., Attalin, V., Avignon, A., Bachert, C., Baroni, I., Bel, E., Benson, M., Bescos, C., Blasi, F., Barbara, C., Bergmann, K.C., Bernard, P. L., Bonini, S., Bousquet, P.J., Branchini, B., Brightling, C.E., Bruguière, V., Bunu, C., Bush, A., Caimmi, D.P., Calderon, M. A., Canovas, G., Cardona, V., Carlsen, K.H., Cesario, A., Chkhartishvili, E., Chiron, R., Chivato, T., Chung, K.F., D’Angelantonio, M., de Carlo, G., Cholley, D., Chorin, F., Combe, B., Compas, B., Costa, D.J., Costa, E., Coste, O., Coupet, A.L., Crepaldi, G., Custovic, A., Dahl, R., Dahlen, S.E., Demoly, P., Devillier, P., Didier, A., Dinh-Xuan, A.T., Djukanovic, R., Dokic, D., du Toit, G., Dubakiene, R., Dupeyron, A., Emuzyte, R., Fiocchi, A., Wagner, A., Fletcher, M., Fonseca, J., Fougère, B., Gamkrelidze, A., Garces, G., Garcia-Aymeric, J., Garcia-Zapirain, B., Gemicioğlu, B., Gouder, C., Hellquist-Dahl, B., Hermosilla-Gimeno, I., Héve, D., Holland, C., Humbert, M., Hyland, M., Johnston, S.L., Just, J., Jutel, M., Kaidashev, I.P., Khaitov, M., Kalayci, O., Kalyoncu, A.F., Keijser, W., Kerstjens, H., Knezović, J., Kowalski, M., Koppelman, G.H., Kotska, T., Kovac, M., Kull, I., Kuna, P., Kvedariene, V., Lepore, V., Macnee, W., Magnan, A., Majer, I., Manning, P., Marcucci, M., Marti, T., Masoli, M., Melen, E., Miculinic, N., Mihaltan, F., Milenkovic, B., Millot-Keurinck, J., Mlinarić, H., Momas, I., Montefort, S., Morais-Almeida, M., Moreno-Casbas, T., Mösges, R., Mullol, J., Nadif, R., Nalin, M., Navarro-Pardo, E., Nekam, K., Ninot, G., Paccard, D., Pais, S., Palummeri, E., Panzner, P., Papadopoulos, N.K., Papanikolaou, C., Passalacqua, G., Pastor, E., Perrot, M., Plavec, D., Popov, T.A., Postma, D. S., Price, D., Raffort, N., Reuzeau, J.C., Robine, J.M., Rodenas, F., Robusto, F., Roche, N., Romano, A., Romano, V., Rosado-Pinto, J., Roubille, F., Ruiz, F., Ryan, D., Salcedo, T., Schmid-Grendelmeier, P., Schulz, H., Schunemann, H.J., Serrano, E., Sheikh, A., Shields, M., Siafakas, N., Scichilone, N., Skrindo, I., Smit, H. A., Sourdet, S., Sousa-Costa, E., Spranger, O., Sooronbaev, T., Sruk, V., Sterk, P. J., Todo-Bom, A., Touchon, J., Tramontano, D., Triggiani, M., Tsartara, S. I., Valero, A. L., Valovirta, E., van Ganse, E., van Hage, M., van Den Berge, M., Ventura, M. T., Vergara, I., Vezzani, G., Vidal, D., Viegi, G., Wagemann, M., Whalley, B., Wilson, N., Yiallouros, P. K., Žagar, M., Zaidi, A., Zidarn, M., Hoogerwerf, E. J., Usero, J., Zuffada, R., Senn, A., and de Oliveira-Alves, B.

Abstract

The Strategic Implementation Plan of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) proposed six Action Groups. After almost three years of activity, many achievements have been obtained through commitments or collaborative work of the Action Groups. However, they have often worked in silos and, consequently, synergies between Action Groups have been proposed to strengthen the triple win of the EIP on AHA. The paper presents the methodology and current status of the Task Force on EIP on AHA synergies. Synergies are in line with the Action Groups’ new Renovated Action Plan (2016-2018) to ensure that their future objectives are coherent and fully connected. The outcomes and impact of synergies are using the Monitoring and Assessment Framework for the EIP on AHA (MAFEIP). Eight proposals for synergies have been approved by the Task Force: Five cross-cutting synergies which can be used for all current and future synergies as they consider overarching domains (appropriate polypharmacy, citizen empowerment, teaching and coaching on AHA, deployment of synergies to EU regions, Responsible Research and Innovation), and three cross-cutting synergies focussing on current Action Group activities (falls, frailty, integrated care and chronic respiratory diseases).

Published
2016

36. Генетичний поліморфізм ASP299GLY гена тол-подібного рецептора 4 в дітей із хелікобактерною інфекцією

Author

Abaturov, O.Ye., Gerasymenko, O.M., Shlykova, O.A., and Kaidashev, I.P.

Subjects
Helicobacter pylori infection, TLR4 ASP299GLY gene polymorphism, children, хеликобактерная инфекция, полиморфизм ASP299GLY гена ТLR4, дети, хелікобактерна інфекція, поліморфізм ASP299GLY гена ТLR4, діти
Abstract

The objective of the study was to determine the characteristics of H.pylori infection in children with Toll-like receptor 4 (TLR4) ASP299GLY gene polymorphism.Methods. 31 children aged 9 to 17 years with chronic gastroduodenal pathology were observed. The control group included 95 healthy individuals.Results. Among children with chronic gastroduodenal pathology, 16.13 % had heterozygous genotype Asp/Gly, which is higher than in the control group (P = 0.01). It was shown that in H.pylori positive children the frequency of the heterozygous genotype Asp/Gly was higher than in H. pylori negative patients (17.4 and 12.5 %, respectively, OR = 1.48; P = 0.75). Among H.pylori positive children heterozygous genotype Asp/Gly was detected more frequently in children infected with СagA-positive strains of H.pylori, compared to patients with СagA-negative status (P > 0.5). It is proved that in children with TLR4 ASP299GLY gene polymorphism a decrease in the expression of TLR4 in biopsy sample of the gastric mucosa and water-soluble sCD14 levels was observed, together with prominent inflammatory mucosal changes (Pu < 0.05).Conclusion. Among children with chronic inflammatory gastroduodenal diseases, genotype Asp/Gly SNP Asp299Gly of the gene TLR4 is observed significantly higher than in healthy population. Presence of genotype Asp/Gly in children predisposes to contamination with H.pylori., Целью исследования было определение особенностей хеликобактерной инфекции у детей с полиморфизмом ASP299GLY гена толл-подобного рецептора 4 (TLR4).Методы. Под наблюдением находился 31 ребенок в возрасте от 9 до 17 лет с хронической гастродуоденальной патологией. Группа контроля — 95 здоровых лиц.Результаты. Среди детей с хронической гастродуоденальной патологией гетерозиготный генотип Asp/Gly имели 16,13 % детей, что превышает показатели в группе контроля (Р = 0,01). Показано, что у детей с положительным Н.pylori-статусом частота гетерозиготного генотипа Asp/Gly была выше, чем у пациентов с Н.pylori-отрицательным статусом (17,4 и 12,5 % соответственно; ОШ = 1,48; Р = 0,75). Среди H.pylori-позитивных детей гетерозиготный генотип Asp/Gly регистрировался чаще у детей, инфицированных СagA-позитивными штаммами Н.pylori, чем у пациентов с СagA-отрицательным статусом (Р > 0,5). Доказано, что у детей с генотипом Asp/Gly полиморфизма гена TLR4 отмечалось снижение экспрессии TLR4 в биоптате слизистой оболочки желудка и уровня водорастворимого sCD14 при сохранении выраженных воспалительных изменений слизистой оболочки (Pu, Метою дослідження було визначення особливостей хелікобактерної інфекції у дітей із поліморфізмом ASP299GLY гена тол-подібного рецептора 4 (TLR4). Методи. Під наглядом була 31 дитина віком від 9 до 17 років із хронічною гастродуоденальною патологією. Група контролю — 95 здорових осіб.Результати. Серед дітей із хронічною гастродуоденальною патологією гетерозиготний генотип Asp/Gly мали 16,13 % дітей, що є вищим за показники групи контролю (Р = 0,01). Показано, що в дітей із позитивним Н.pylori-статусом питома вага гетерозиготного генотипу Asp/Gly була вищою, ніж у пацієнтів із Н.pylori-негативним статусом (17,4 та 12,5 % відповідно; ВШ = 1,48; P = 0,75). Серед H.pylori-позитивних дітей гетерозиготний генотип Asp/Gly виявлявся частіше в дітей, інфікованих СagA-позитивними штамами Н.pylori, ніж у пацієнтів із СagA-негативним статусом (Р > 0,5). Доведено, що в дітей із генотипом Asp/Gly поліморфізму гена TLR4 відзначалося зниження експресії TLR4 у біоптаті слизової оболонки шлунка й рівня водорозчинного sCD14 при збереженні виражених запальних змін слизової оболонки (Pu < 0,05). Висновок. Серед дітей із хронічними запальними гастродуоденальними захворюваннями вірогідно частіше, ніж у групі здорових осіб, зустрічається генотип Asp/Gly SNP Asp299Gly гена TLR4. Наявність у дітей генотипу Asp/Gly зумовлює схильність до інфікування Н.pylori.

Published
2013

37. MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): The new generation guideline implementation

Author

Bousquet, J. Schunemann, H.J. Fonseca, J. Samolinski, B. Bachert, C. Canonica, G.W. Casale, T. Cruz, A.A. Demoly, P. Hellings, P. Valiulis, A. Wickman, M. Zuberbier, T. Bosnic-Anticevitch, S. Bedbrook, A. Bergmann, K.C. Caimmi, D. Dahl, R. Fokkens, W.J. Grisle, I. Lodrup Carlsen, K. Mullol, J. Muraro, A. Palkonen, S. Papadopoulos, N. Passalacqua, G. Ryan, D. Valovirta, E. Yorgancioglu, A. Aberer, W. Agache, I. Adachi, M. Akdis, C.A. Akdis, M. Annesi-Maesano, I. Ansotegui, I.J. Anto, J.M. Arnavielhe, S. Arshad, H. Baiardini, I. Baigenzhin, A.K. Barbara, C. Bateman, E.D. Beghé, B. Bel, E.H. Ben Kheder, A. Bennoor, K.S. Benson, M. Bewick, M. Bieber, T. Bindslev-Jensen, C. Bjermer, L. Blain, H. Boner, A.L. Boulet, L.P. Bonini, M. Bonini, S. Bosse, I. Bourret, R. Bousquet, P.J. Braido, F. Briggs, A.H. Brightling, C.E. Brozek, J. Buhl, R. Burney, P.G. Bush, A. Caballero-Fonseca, F. Calderon, M.A. Camargos, P.A.M. Camuzat, T. Carlsen, K.H. Carr, W. Cepeda Sarabia, A.M. Chavannes, N.H. Chatzi, L. Chen, Y.Z. Chiron, R. Chkhartishvili, E. Chuchalin, A.G. Ciprandi, G. Cirule, I. Correia De Sousa, J. Cox, L. Crooks, G. Costa, D.J. Custovic, A. Dahlen, S.E. Darsow, U. De Carlo, G. De Blay, F. Dedeu, T. Deleanu, D. Denburg, J.A. Devillier, P. Didier, A. Dinh-Xuan, A.T. Dokic, D. Douagui, H. Dray, G. Dubakiene, R. Durham, S.R. Dykewicz, M.S. El-Gamal, Y. Emuzyte, R. Fink Wagner, A. Fletcher, M. Fiocchi, A. Forastiere, F. Gamkrelidze, A. Gemicioʇlu, B. Gereda, J.E. González Diaz, S. Gotua, M. Grouse, L. Guzmán, M.A. Haahtela, T. Hellquist-Dahl, B. Heinrich, J. Horak, F. Hourihane, J.O.B. Howarth, P. Humbert, M. Hyland, M.E. Ivancevich, J.C. Jares, E.J. Johnston, S.L. Joos, G. Jonquet, O. Jung, K.S. Just, J. Kaidashev, I.P. Kalayci, O. Kalyoncu, A.F. Keil, T. Keith, P.K. Khaltaev, N. Klimek, L. Koffi N'Goran, B. Kolek, V. Koppelman, G.H. Kowalski, M.L. Kull, I. Kuna, P. Kvedariene, V. Lambrecht, B. Lau, S. Larenas-Linnemann, D. Laune, D. Le, L.T.T. Lieberman, P. Lipworth, B. Li and Bousquet, J. Schunemann, H.J. Fonseca, J. Samolinski, B. Bachert, C. Canonica, G.W. Casale, T. Cruz, A.A. Demoly, P. Hellings, P. Valiulis, A. Wickman, M. Zuberbier, T. Bosnic-Anticevitch, S. Bedbrook, A. Bergmann, K.C. Caimmi, D. Dahl, R. Fokkens, W.J. Grisle, I. Lodrup Carlsen, K. Mullol, J. Muraro, A. Palkonen, S. Papadopoulos, N. Passalacqua, G. Ryan, D. Valovirta, E. Yorgancioglu, A. Aberer, W. Agache, I. Adachi, M. Akdis, C.A. Akdis, M. Annesi-Maesano, I. Ansotegui, I.J. Anto, J.M. Arnavielhe, S. Arshad, H. Baiardini, I. Baigenzhin, A.K. Barbara, C. Bateman, E.D. Beghé, B. Bel, E.H. Ben Kheder, A. Bennoor, K.S. Benson, M. Bewick, M. Bieber, T. Bindslev-Jensen, C. Bjermer, L. Blain, H. Boner, A.L. Boulet, L.P. Bonini, M. Bonini, S. Bosse, I. Bourret, R. Bousquet, P.J. Braido, F. Briggs, A.H. Brightling, C.E. Brozek, J. Buhl, R. Burney, P.G. Bush, A. Caballero-Fonseca, F. Calderon, M.A. Camargos, P.A.M. Camuzat, T. Carlsen, K.H. Carr, W. Cepeda Sarabia, A.M. Chavannes, N.H. Chatzi, L. Chen, Y.Z. Chiron, R. Chkhartishvili, E. Chuchalin, A.G. Ciprandi, G. Cirule, I. Correia De Sousa, J. Cox, L. Crooks, G. Costa, D.J. Custovic, A. Dahlen, S.E. Darsow, U. De Carlo, G. De Blay, F. Dedeu, T. Deleanu, D. Denburg, J.A. Devillier, P. Didier, A. Dinh-Xuan, A.T. Dokic, D. Douagui, H. Dray, G. Dubakiene, R. Durham, S.R. Dykewicz, M.S. El-Gamal, Y. Emuzyte, R. Fink Wagner, A. Fletcher, M. Fiocchi, A. Forastiere, F. Gamkrelidze, A. Gemicioʇlu, B. Gereda, J.E. González Diaz, S. Gotua, M. Grouse, L. Guzmán, M.A. Haahtela, T. Hellquist-Dahl, B. Heinrich, J. Horak, F. Hourihane, J.O.B. Howarth, P. Humbert, M. Hyland, M.E. Ivancevich, J.C. Jares, E.J. Johnston, S.L. Joos, G. Jonquet, O. Jung, K.S. Just, J. Kaidashev, I.P. Kalayci, O. Kalyoncu, A.F. Keil, T. Keith, P.K. Khaltaev, N. Klimek, L. Koffi N'Goran, B. Kolek, V. Koppelman, G.H. Kowalski, M.L. Kull, I. Kuna, P. Kvedariene, V. Lambrecht, B. Lau, S. Larenas-Linnemann, D. Laune, D. Le, L.T.T. Lieberman, P. Lipworth, B. Li

Abstract

Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for integrated care pathways, innovation in clinical trials and, above all, patient empowerment. MASK-rhinitis (MACVIA-ARIA Sentinel NetworK for allergic rhinitis) is a simple system centred around the patient which was devised to fill many of these gaps using Information and Communications Technology (ICT) tools and a clinical decision support system (CDSS) based on the most widely used guideline in allergic rhinitis and its asthma comorbidity (ARIA 2015 revision). It is one of the implementation systems of Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA). Three tools are used for the electronic monitoring of allergic diseases: a cell phone-based daily visual analogue scale (VAS) assessment of disease control, CARAT (Control of Allergic Rhinitis and Asthma Test) and e-Allergy screening (premedical system of early diagnosis of allergy and asthma based on online tools). These tools are combined with a clinical decision support system (CDSS) and are available in many languages. An e-CRF and an e-learning tool complete MASK. MASK is flexible and other tools can be added. It appears to be an advanced, global and integrated ICT answer for many unmet needs in allergic diseases which will improve policies and standards. © 2015 John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

Published
2015

42. MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis

Author

Bousquet, J., Schünemann, H.J., Hellings, P.W., Arnavielhe, S., Bachert, C., Bedbrook, A., Bergmann, K.C., Bosnic-Anticevich, S., Brozek, J., Calderon, M., Canonica, G.W., Casale, T.B., Chavannes, N.H., Cox, L., Chrystyn, H., Cruz, A.A., Dahl, R., De Carlo, G., Demoly, P., Devillier, P., Dray, G., Fletcher, M., Fokkens, W.J., Fonseca, J., Gonzalez-Diaz, S.N., Grouse, L., Keil, T., Kuna, P., Larenas-Linnemann, D., Lodrup Carlsen, K.C., Meltzer, E.O., Mullol, J., Muraro, A., Naclerio, R.N., Palkonen, S., Papadopoulos, N.G., Passalacqua, G., Price, D., Ryan, D., Samolinski, B., Scadding, G.K., Sheikh, A., Spertini, F., Valiulis, A., Valovirta, E., Walker, S., Wickman, M., Yorgancioglu, A., Haahtela, T., Zuberbier, T., MASK study group, Aberer, W., Adachi, M., Agache, I., Akdis, C., Akdis, M., Annesi-Maesano, I., Ansotegui, I.J., Anto, J.M., Arshad, S.H., Baiardini, I., Baigenzhin, A.K., Barbara, C., Bateman, E.D., Beghé, B., Bel, E.H., Ben Kheder, A., Bennoor, K.S., Benson, M., Bernstein, D., Michael, B., Thomas, B., Bindslev-Jensen, C., Bjermer, L., Blain, H., Boner, A., Bonini, M., Bonini, S., Bosse, I., Bouchard, J., Boulet, L.P., Bourret, R.A., Bousquet, P.J., Braido, F., Briggs, A.H., Brightling, C.E., Buhl, R., Burney, P., Bush, A., Caballero-Fonseca, F., Caimmi, D.P., Camargos, P., Camuzat, T., Carlsen, K.H., Carr, W., Casale, T.B., Sarabia, A.C., Chatzi, L., Chen, Y., Chiron, R., Chkhartishvili, E., Chuchalin, A., Ciprandi, G., Cirule, I., Correia de Sousa, J., Costa, D., Crooks, G., Custovic, A., Dahlen, S.E., Darsow, U., De Blay, F., De Manuel Keenoy, E., Dedeu, T., Deleanu, D., Denburg, J., Didier, A., Dinh-Xuan, A.T., Dokic, D., Douagui, H.B., Dubakiene, R., Durham, S., Dykewicz, M., El-Gamal, Y., Emuzyte, R., Fink-Wagner, A., Fiocchi, A., Forastiere, F., Gamkrelidze, A., Gemicioğlu, B., Gereda, J.E., Gerth van Wijk, R., Gotua, M., Grisle, I., Guzmán, M.A., Haahtela, T., Heinrich, J., Hellquist-Dahl, B., Horak, F., Howarth, P.H., Humbert, M., Hyland, M., Ivancevich, J.C., Jares, E.J., Johnston, S.L., Jonquet, O., Joos, G., Jung, K.S., Just, J., Jutel, M., Kaidashev, I.P., Khaitov, M., Kalayci, O., Kalyoncu, F., Keith, P., Khaltaev, N., Kleine-Tebbe, J., Klimek, L., N'Goran, B.K., Kolek, V., Koppelman, G.H., Kowalski, M., Kull, I., Kvedariene, V., Lambrecht, B., Lau, S., Laune, D., Le Thi Tuyet, L., Li, J., Lieberman, P., Lipworth, B.J., Renaud, L., Magard, Y., Magnan, A., Mahboub, B., Majer, I., Makela, M., Manning, P.J., Masjedi, M.R., Maurer, M., Mavale-Manuel, S., Melén, E., Melo-Gomes, E., Mercier, J., Merk, H., Miculinic, N., Mihaltan, F., Milenkovic, B., Mohammad, Y., Molimard, M., Momas, I., Montilla-Santana, A., Morais-Almeida, M., Mösges, R., Nadif, R., Namazova-Baranova, L., Neffen, H., Nekam, K., Neou, A., Niggemann, B., Nyembue, D., O'Hehir, R., Ohta, K., Okamoto, Y., Okubo, K., Ouedraogo, S., Paggiaro, P.L., Pali-Schöll, I., Palmer, S., Panzner, P., Papi, A., Park, H.S., Pavord, I., Pawankar, R., Pfaar, O., Picard, R., Pigearias, B., Pin, I., Plavec, D., Pohl, W., Popov, T., Postma, D.S., Potter, P., Poulsen, L.K., Rabe, K.F., Raciborski, F., Pontal, F.R., Reitamo, S., Repka-Ramirez, M.S., Robalo-Cordeiro, C., Roberts, G., Rodenas, F., Rolland, C., Rodriguez, M.R., Romano, A., Rosado-Pinto, J., Rosario, N.A., Rosenwasser, L., Rottem, M., Sanchez-Borges, M., Sastre-Dominguez, J., Schmid-Grendelmeier, P., Serrano, E., Simons, F.E., Sisul, J.C., Skrindo, I., Smit, H.A., Solé, D., Sooronbaev, T., Spranger, O., Stelmach, R., Strandberg, T., Sunyer, J., Thijs, C., Todo-Bom, A.M., Triggiani, M., Valenta, R., Valero, A.L., van Hage, M., Vandenplas, O., Vezzani, G., Vichyanond, P., Viegi, G., Wagenmann, M., Wahn, U., De Yun, W., Williams, D., Wright, J., Yawn, B.P., Yiallouros, P., Yusuf, O.M., Zar, H.J., Zernotti, M., Zhang, L., Zhong, N., and Zidarn, M.

Subjects
Adolescent, Adult, Age Factors, Algorithms, Clinical Decision-Making, Conjunctivitis, Allergic/diagnosis, Conjunctivitis, Allergic/prevention & control, Conjunctivitis, Allergic/therapy, Disease Management, Humans, Patient Satisfaction, Rhinitis, Allergic/diagnosis, Rhinitis, Allergic/prevention & control, Rhinitis, Allergic/therapy
Abstract

The selection of pharmacotherapy for patients with allergic rhinitis (AR) depends on several factors, including age, prominent symptoms, symptom severity, control of AR, patient preferences, and cost. Allergen exposure and the resulting symptoms vary, and treatment adjustment is required. Clinical decision support systems (CDSSs) might be beneficial for the assessment of disease control. CDSSs should be based on the best evidence and algorithms to aid patients and health care professionals to jointly determine treatment and its step-up or step-down strategy depending on AR control. Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR [fighting chronic diseases for active and healthy ageing]), one of the reference sites of the European Innovation Partnership on Active and Healthy Ageing, has initiated an allergy sentinel network (the MACVIA-ARIA Sentinel Network). A CDSS is currently being developed to optimize AR control. An algorithm developed by consensus is presented in this article. This algorithm should be confirmed by appropriate trials.

Published
2016

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